unprocessed
stringlengths 304
936
| processed
stringlengths 4
1.01k
|
|---|---|
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: BACKGROUND : Tacrolimus ointment is increasingly used for anti - inflammatory treatment of sensitive areas such as the face , and recent observations indicate that the treatment is effective in steroid - aggravated rosacea and perioral dermatitis .
### Output Text: | BACKGROUND : <span class="chemical">Tacrolimus</span> ointment is increasingly used for anti - inflammatory treatment of sensitive areas such as the face , and recent observations indicate that the treatment is effective in <span class="chemical">steroid</span> - aggravated rosacea and perioral dermatitis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We report on rosaceiform dermatitis as a complication of treatment with tacrolimus ointment .
### Output Text: | We report on rosaceiform dermatitis as a complication of treatment with <span class="chemical">tacrolimus</span> ointment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: OBSERVATIONS : Six adult patients with inflammatory facial dermatoses were treated with tacrolimus ointment because of the ineffectiveness of standard treatments .
### Output Text: | OBSERVATIONS : Six adult patients with inflammatory facial dermatoses were treated with <span class="chemical">tacrolimus</span> ointment because of the ineffectiveness of standard treatments . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Within 2 to 3 weeks of initially effective and well - tolerated treatment , 3 patients with a history of rosacea and 1 with a history of acne experienced sudden worsening with pustular rosaceiform lesions .
### Output Text: | Within 2 to 3 weeks of initially effective and well - tolerated treatment , 3 patients with a history of rosacea and 1 with a history of acne experienced sudden worsening with pustular rosaceiform lesions . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Biopsy revealed an abundance of Demodex mites in 2 of these patients .
### Output Text: | Biopsy revealed an abundance of Demodex mites in 2 of these patients . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: In 1 patient with eyelid eczema , rosaceiform periocular dermatitis gradually appeared after 3 weeks of treatment .
### Output Text: | In 1 patient with eyelid eczema , rosaceiform periocular dermatitis gradually appeared after 3 weeks of treatment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: In 1 patient with atopic dermatitis , telangiectatic and papular rosacea insidiously appeared after 5 months of treatment .
### Output Text: | In 1 patient with atopic dermatitis , telangiectatic and papular rosacea insidiously appeared after 5 months of treatment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSIONS : Our observations suggest that the spectrum of rosaceiform dermatitis as a complication of treatment with tacrolimus ointment is heterogeneous .
### Output Text: | CONCLUSIONS : Our observations suggest that the spectrum of rosaceiform dermatitis as a complication of treatment with <span class="chemical">tacrolimus</span> ointment is heterogeneous . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A variety of factors , such as vasoactive properties of tacrolimus , proliferation of Demodex due to local immunosuppression , and the occlusive properties of the ointment , may be involved in the observed phenomena .
### Output Text: | A variety of factors , such as vasoactive properties of <span class="chemical">tacrolimus</span> , proliferation of Demodex due to local immunosuppression , and the occlusive properties of the ointment , may be involved in the observed phenomena . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Future studies are needed to identify individual risk factors .
### Output Text: | Future studies are needed to identify individual risk factors . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Intravascular hemolysis and acute renal failure following intermittent rifampin therapy .
### Output Text: | Intravascular hemolysis and acute renal failure following intermittent <span class="chemical">rifampin</span> therapy . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Renal failure is a rare complication associated with the use of rifampin .
### Output Text: | Renal failure is a rare complication associated with the use of <span class="chemical">rifampin</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Intravascular hemolysis leading to acute renal failure following rifampin therapy is extremely rare .
### Output Text: | Intravascular hemolysis leading to acute renal failure following <span class="chemical">rifampin</span> therapy is extremely rare . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Two patients with leprosy who developed hemolysis and acute renal failure following rifampin are reported .
### Output Text: | Two patients with leprosy who developed hemolysis and acute renal failure following <span class="chemical">rifampin</span> are reported . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Structural abnormalities in the brains of human subjects who use methamphetamine .
### Output Text: | Structural abnormalities in the brains of human subjects who use <span class="chemical">methamphetamine</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We visualize , for the first time , the profile of structural deficits in the human brain associated with chronic methamphetamine ( MA ) abuse .
### Output Text: | We visualize , for the first time , the profile of structural deficits in the human brain associated with chronic <span class="chemical">methamphetamine</span> ( <span class="chemical">MA</span> ) abuse . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Studies of human subjects who have used MA chronically have revealed deficits in dopaminergic and serotonergic systems and cerebral metabolic abnormalities .
### Output Text: | Studies of human subjects who have used <span class="chemical">MA</span> chronically have revealed deficits in dopaminergic and serotonergic systems and cerebral metabolic abnormalities . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Using magnetic resonance imaging ( MRI ) and new computational brain - mapping techniques , we determined the pattern of structural brain alterations associated with chronic MA abuse in human subjects and related these deficits to cognitive impairment .
### Output Text: | Using magnetic resonance imaging ( MRI ) and new computational brain - mapping techniques , we determined the pattern of structural brain alterations associated with chronic <span class="chemical">MA</span> abuse in human subjects and related these deficits to cognitive impairment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We used high - resolution MRI and surface - based computational image analyses to map regional abnormalities in the cortex , hippocampus , white matter , and ventricles in 22 human subjects who used MA and 21 age - matched , healthy controls .
### Output Text: | We used high - resolution MRI and surface - based computational image analyses to map regional abnormalities in the cortex , hippocampus , white matter , and ventricles in 22 human subjects who used <span class="chemical">MA</span> and 21 age - matched , healthy controls . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Cortical maps revealed severe gray - matter deficits in the cingulate , limbic , and paralimbic cortices of MA abusers ( averaging 11 . 3 % below control ; p < 0 . 05 ) .
### Output Text: | Cortical maps revealed severe gray - matter deficits in the cingulate , limbic , and paralimbic cortices of <span class="chemical">MA</span> abusers ( averaging 11 . 3 % below control ; p < 0 . 05 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: On average , MA abusers had 7 . 8 % smaller hippocampal volumes than control subjects ( p < 0 . 01 ; left , p = 0 . 01 ; right , p < 0 . 05 ) and significant white - matter hypertrophy ( 7 . 0 % ; p < 0 . 01 ) .
### Output Text: | On average , <span class="chemical">MA</span> abusers had 7 . 8 % smaller hippocampal volumes than control subjects ( p < 0 . 01 ; left , p = 0 . 01 ; right , p < 0 . 05 ) and significant white - matter hypertrophy ( 7 . 0 % ; p < 0 . 01 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Hippocampal deficits were mapped and correlated with memory performance on a word - recall test ( p < 0 . 05 ) .
### Output Text: | Hippocampal deficits were mapped and correlated with memory performance on a word - recall test ( p < 0 . 05 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: MRI - based maps suggest that chronic methamphetamine abuse causes a selective pattern of cerebral deterioration that contributes to impaired memory performance .
### Output Text: | MRI - based maps suggest that chronic <span class="chemical">methamphetamine</span> abuse causes a selective pattern of cerebral deterioration that contributes to impaired memory performance . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: MA may selectively damage the medial temporal lobe and , consistent with metabolic studies , the cingulate - limbic cortex , inducing neuroadaptation , neuropil reduction , or cell death .
### Output Text: | <span class="chemical">MA</span> may selectively damage the medial temporal lobe and , consistent with metabolic studies , the cingulate - limbic cortex , inducing neuroadaptation , neuropil reduction , or cell death . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Prominent white - matter hypertrophy may result from altered myelination and adaptive glial changes , including gliosis secondary to neuronal damage .
### Output Text: | Prominent white - matter hypertrophy may result from altered myelination and adaptive glial changes , including gliosis secondary to neuronal damage . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: These brain substrates may help account for the symptoms of MA abuse , providing therapeutic targets for drug - induced brain injury .
### Output Text: | These brain substrates may help account for the symptoms of <span class="chemical">MA</span> abuse , providing therapeutic targets for drug - induced brain injury . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator - activated receptor - alpha target gene activation .
### Output Text: | Disruption of hepatic lipid homeostasis in mice after <span class="chemical">amiodarone</span> treatment is associated with peroxisome proliferator - activated receptor - alpha target gene activation . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Amiodarone , an efficacious and widely used antiarrhythmic agent , has been reported to cause hepatotoxicity in some patients .
### Output Text: | <span class="chemical">Amiodarone</span> , an efficacious and widely used antiarrhythmic agent , has been reported to cause hepatotoxicity in some patients . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: To gain insight into the mechanism of this unwanted effect , mice were administered various doses of amiodarone and examined for changes in hepatic histology and gene regulation .
### Output Text: | To gain insight into the mechanism of this unwanted effect , mice were administered various doses of <span class="chemical">amiodarone</span> and examined for changes in hepatic histology and gene regulation . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Amiodarone induced hepatomegaly , hepatocyte microvesicular lipid accumulation , and a significant decrease in serum triglycerides and glucose .
### Output Text: | <span class="chemical">Amiodarone</span> induced hepatomegaly , hepatocyte microvesicular lipid accumulation , and a significant decrease in serum <span class="chemical">triglycerides</span> and <span class="chemical">glucose</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Northern blot analysis of hepatic RNA revealed a dose - dependent increase in the expression of a number of genes critical for fatty acid oxidation , lipoprotein assembly , and lipid transport .
### Output Text: | Northern blot analysis of hepatic RNA revealed a dose - dependent increase in the expression of a number of genes critical for <span class="chemical">fatty acid</span> oxidation , lipoprotein assembly , and lipid transport . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Many of these genes are regulated by the peroxisome proliferator - activated receptor - alpha ( PPARalpha ) , a ligand - activated nuclear hormone receptor transcription factor .
### Output Text: | Many of these genes are regulated by the peroxisome proliferator - activated receptor - alpha ( PPARalpha ) , a ligand - activated nuclear hormone receptor transcription factor . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The absence of induction of these genes as well as hepatomegaly in PPARalpha knockout [ PPARalpha - / - ] mice indicated that the effects of amiodarone were dependent upon the presence of a functional PPARalpha gene .
### Output Text: | The absence of induction of these genes as well as hepatomegaly in PPARalpha knockout [ PPARalpha - / - ] mice indicated that the effects of <span class="chemical">amiodarone</span> were dependent upon the presence of a functional PPARalpha gene . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Compared to wild - type mice , treatment of PPARalpha - / - mice with amiodarone resulted in an increased rate and extent of total body weight loss .
### Output Text: | Compared to wild - type mice , treatment of PPARalpha - / - mice with <span class="chemical">amiodarone</span> resulted in an increased rate and extent of total body weight loss . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The inability of amiodarone to directly activate either human or mouse PPARalpha transiently expressed in human HepG2 hepatoma cells indicates that the effects of amiodarone on the function of this receptor were indirect .
### Output Text: | The inability of <span class="chemical">amiodarone</span> to directly activate either human or mouse PPARalpha transiently expressed in human HepG2 hepatoma cells indicates that the effects of <span class="chemical">amiodarone</span> on the function of this receptor were indirect . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Based upon these results , we conclude that amiodarone disrupts hepatic lipid homeostasis and that the increased expression of PPARalpha target genes is secondary to this toxic effect .
### Output Text: | Based upon these results , we conclude that <span class="chemical">amiodarone</span> disrupts hepatic lipid homeostasis and that the increased expression of PPARalpha target genes is secondary to this toxic effect . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: These results provide important new mechanistic information regarding the hepatotoxic effects of amiodarone and indicate that PPARalpha protects against amiodarone - induced hepatotoxicity .
### Output Text: | These results provide important new mechanistic information regarding the hepatotoxic effects of <span class="chemical">amiodarone</span> and indicate that PPARalpha protects against <span class="chemical">amiodarone</span> - induced hepatotoxicity . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Safety and compliance with once - daily niacin extended - release / lovastatin as initial therapy in the Impact of Medical Subspecialty on Patient Compliance to Treatment ( IMPACT ) study .
### Output Text: | Safety and compliance with once - daily <span class="chemical">niacin extended - release / lovastatin</span> as initial therapy in the Impact of Medical Subspecialty on Patient Compliance to Treatment ( IMPACT ) study . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Niacin extended - release / lovastatin is a new combination product approved for treatment of primary hypercholesterolemia and mixed dyslipidemia .
### Output Text: | <span class="chemical">Niacin extended - release / lovastatin</span> is a new combination product approved for treatment of primary hypercholesterolemia and mixed dyslipidemia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: This open - labeled , multicenter study evaluated the safety of bedtime niacin extended - release / lovastatin when dosed as initial therapy and patient compliance to treatment in various clinical practice settings .
### Output Text: | This open - labeled , multicenter study evaluated the safety of bedtime <span class="chemical">niacin extended - release / lovastatin</span> when dosed as initial therapy and patient compliance to treatment in various clinical practice settings . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A total of 4 , 499 patients with dyslipidemia requiring drug intervention was enrolled at 1 , 081 sites .
### Output Text: | A total of 4 , 499 patients with dyslipidemia requiring drug intervention was enrolled at 1 , 081 sites . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Patients were treated with 1 tablet ( 500 mg of niacin extended - release / 20 mg of lovastatin ) once nightly for 4 weeks and then 2 tablets for 8 weeks .
### Output Text: | Patients were treated with 1 tablet ( 500 mg of <span class="chemical">niacin</span> extended - release / 20 mg of <span class="chemical">lovastatin</span> ) once nightly for 4 weeks and then 2 tablets for 8 weeks . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Patients also received dietary counseling , educational materials , and reminders to call a toll - free number that provided further education about dyslipidemia and niacin extended - release / lovastatin .
### Output Text: | Patients also received dietary counseling , educational materials , and reminders to call a toll - free number that provided further education about dyslipidemia and <span class="chemical">niacin extended - release / lovastatin</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Primary end points were study compliance , increases in liver transaminases to > 3 times the upper limit of normal , and clinical myopathy .
### Output Text: | Primary end points were study compliance , increases in liver transaminases to > 3 times the upper limit of normal , and clinical myopathy . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Final study status was available for 4 , 217 patients ( 94 % ) .
### Output Text: | Final study status was available for 4 , 217 patients ( 94 % ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Compliance to niacin extended - release / lovastatin was 77 % , with 3 , 245 patients completing the study .
### Output Text: | Compliance to <span class="chemical">niacin extended - release / lovastatin</span> was 77 % , with 3 , 245 patients completing the study . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Patients in the southeast and those enrolled by endocrinologists had the lowest compliance and highest adverse event rates .
### Output Text: | Patients in the southeast and those enrolled by endocrinologists had the lowest compliance and highest adverse event rates . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Flushing was the most common adverse event , reported by 18 % of patients and leading to discontinuation by 6 % .
### Output Text: | Flushing was the most common adverse event , reported by 18 % of patients and leading to discontinuation by 6 % . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Incidence of increased aspartate aminotransferase and / or alanine aminotransferase > 3 times the upper limit of normal was < 0 . 3 % .
### Output Text: | Incidence of increased <span class="chemical">aspartate</span> aminotransferase and / or <span class="chemical">alanine</span> aminotransferase > 3 times the upper limit of normal was < 0 . 3 % . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: An increase of creatine phosphokinase to > 5 times the upper limit of normal occurred in 0 . 24 % of patients , and no cases of drug - induced myopathy were observed .
### Output Text: | An increase of <span class="chemical">creatine</span> phosphokinase to > 5 times the upper limit of normal occurred in 0 . 24 % of patients , and no cases of drug - induced myopathy were observed . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Niacin extended - release / lovastatin 1 , 000 / 40 mg , dosed as initial therapy , was associated with good compliance and safety and had very low incidences of increased liver and muscle enzymes .
### Output Text: | <span class="chemical">Niacin extended - release / lovastatin</span> 1 , 000 / 40 mg , dosed as initial therapy , was associated with good compliance and safety and had very low incidences of increased liver and muscle enzymes . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol .
### Output Text: | Protective effect of <span class="chemical">Terminalia chebula</span> against experimental myocardial injury induced by <span class="chemical">isoproterenol</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Cardioprotective effect of ethanolic extract of Terminalia chebula fruits ( 500 mg / kg body wt ) was examined in isoproterenol ( 200 mg / kg body wt ) induced myocardial damage in rats .
### Output Text: | Cardioprotective effect of <span class="chemical">ethanolic extract of Terminalia chebula fruits</span> ( 500 mg / kg body wt ) was examined in <span class="chemical">isoproterenol</span> ( 200 mg / kg body wt ) induced myocardial damage in rats . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: In isoproterenol administered rats , the level of lipid peroxides increased significantly in the serum and heart .
### Output Text: | In <span class="chemical">isoproterenol</span> administered rats , the level of lipid <span class="chemical">peroxides</span> increased significantly in the serum and heart . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A significant decrease was observed in the activity of the myocardial marker enzymes with a concomitant increase in their activity in serum .
### Output Text: | A significant decrease was observed in the activity of the myocardial marker enzymes with a concomitant increase in their activity in serum . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Histopathological examination was carried out to confirm the myocardial necrosis .
### Output Text: | Histopathological examination was carried out to confirm the myocardial necrosis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: T . chebula extract pretreatment was found to ameliorate the effect of isoproterenol on lipid peroxide formation and retained the activities of the diagnostic marker enzymes .
### Output Text: | <span class="chemical">T . chebula extract</span> pretreatment was found to ameliorate the effect of <span class="chemical">isoproterenol</span> on lipid <span class="chemical">peroxide</span> formation and retained the activities of the diagnostic marker enzymes . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A case of postoperative anxiety due to low dose droperidol used with patient - controlled analgesia .
### Output Text: | A case of postoperative anxiety due to low dose <span class="chemical">droperidol</span> used with patient - controlled analgesia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A multiparous woman in good psychological health underwent urgent caesarean section in labour .
### Output Text: | A multiparous woman in good psychological health underwent urgent caesarean section in labour . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Postoperatively , she was given a patient - controlled analgesia device delivering boluses of diamorphine 0 . 5 mg and droperidol 0 . 025 mg .
### Output Text: | Postoperatively , she was given a patient - controlled analgesia device delivering boluses of <span class="chemical">diamorphine</span> 0 . 5 mg and <span class="chemical">droperidol</span> 0 . 025 mg . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Whilst using the device she gradually became anxious , the feeling worsening after each bolus .
### Output Text: | Whilst using the device she gradually became anxious , the feeling worsening after each bolus . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The diagnosis of droperidol - induced psychological disturbance was not made straight away although on subsequent close questioning the patient gave a very clear history .
### Output Text: | The diagnosis of <span class="chemical">droperidol</span> - induced psychological disturbance was not made straight away although on subsequent close questioning the patient gave a very clear history . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: After she had received a total of only 0 . 9 mg droperidol , a syringe containing diamorphine only was substituted and her unease resolved completely .
### Output Text: | After she had received a total of only 0 . 9 mg <span class="chemical">droperidol</span> , a syringe containing <span class="chemical">diamorphine</span> only was substituted and her unease resolved completely . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We feel that , although the dramatic extrapyramidal side effects of dopaminergic antiemetics are well known , more subtle manifestations may easily be overlooked .
### Output Text: | We feel that , although the dramatic extrapyramidal side effects of dopaminergic antiemetics are well known , more subtle manifestations may easily be overlooked . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Accurate patient history contributes to differentiating diabetes insipidus : a case study .
### Output Text: | Accurate patient history contributes to differentiating diabetes insipidus : a case study . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: This case study highlights the important contribution of nursing in obtaining an accurate health history .
### Output Text: | This case study highlights the important contribution of nursing in obtaining an accurate health history . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The case discussed herein initially appeared to be neurogenic diabetes insipidus ( DI ) secondary to a traumatic brain injury .
### Output Text: | The case discussed herein initially appeared to be neurogenic diabetes insipidus ( DI ) secondary to a traumatic brain injury . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The nursing staff , by reviewing the patient ' s health history with his family , discovered a history of polydipsia and long - standing lithium use .
### Output Text: | The nursing staff , by reviewing the patient ' s health history with his family , discovered a history of polydipsia and long - standing <span class="chemical">lithium</span> use . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Lithium is implicated in drug - induced nephrogenic DI , and because the patient had not received lithium since being admitted to the hospital , his treatment changed to focus on nephrogenic DI .
### Output Text: | <span class="chemical">Lithium</span> is implicated in drug - induced nephrogenic DI , and because the patient had not received <span class="chemical">lithium</span> since being admitted to the hospital , his treatment changed to focus on nephrogenic DI . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: By combining information from the patient history , the physical examination , and radiologic and laboratory studies , the critical care team demonstrated that the patient had been self - treating his lithium - induced nephrogenic DI and developed neurogenic DI secondary to brain trauma .
### Output Text: | By combining information from the patient history , the physical examination , and radiologic and laboratory studies , the critical care team demonstrated that the patient had been self - treating his <span class="chemical">lithium</span> - induced nephrogenic DI and developed neurogenic DI secondary to brain trauma . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Thus successful treatment required that nephrogenic and neurogenic DI be treated concomitantly .
### Output Text: | Thus successful treatment required that nephrogenic and neurogenic DI be treated concomitantly . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Factors contributing to ribavirin - induced anemia .
### Output Text: | Factors contributing to <span class="chemical">ribavirin</span> - induced anemia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: BACKGROUND AND AIM : Interferon and ribavirin combination therapy for chronic hepatitis C produces hemolytic anemia .
### Output Text: | BACKGROUND AND AIM : <span class="chemical">Interferon</span> and <span class="chemical">ribavirin</span> combination therapy for chronic hepatitis C produces hemolytic anemia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: This study was conducted to identify the factors contributing to ribavirin - induced anemia .
### Output Text: | This study was conducted to identify the factors contributing to <span class="chemical">ribavirin</span> - induced anemia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: METHODS : Eighty - eight patients with chronic hepatitis C who received interferon - alpha - 2b at a dose of 6 MU administered intramuscularly for 24 weeks in combination with ribavirin administered orally at a dose of 600 mg or 800 mg participated in the study .
### Output Text: | METHODS : Eighty - eight patients with chronic hepatitis C who received <span class="chemical">interferon - alpha - 2b</span> at a dose of 6 MU administered intramuscularly for 24 weeks in combination with <span class="chemical">ribavirin</span> administered orally at a dose of 600 mg or 800 mg participated in the study . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A hemoglobin concentration of < 10 g / dL was defined as ribavirin - induced anemia .
### Output Text: | A hemoglobin concentration of < 10 g / dL was defined as <span class="chemical">ribavirin</span> - induced anemia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: RESULTS : Ribavirin - induced anemia occurred in 18 ( 20 . 5 % ) patients during treatment .
### Output Text: | RESULTS : <span class="chemical">Ribavirin</span> - induced anemia occurred in 18 ( 20 . 5 % ) patients during treatment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A 2 g / dL decrease in hemoglobin concentrations in patients with anemia was observed at week 2 after the start of treatment .
### Output Text: | A 2 g / dL decrease in hemoglobin concentrations in patients with anemia was observed at week 2 after the start of treatment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The hemoglobin concentration in patients with > or = 2 g / dL decrease at week 2 was observed to be significantly lower even after week 2 than in patients with < 2 g / dL decrease ( P < 0 . 01 ) .
### Output Text: | The hemoglobin concentration in patients with > or = 2 g / dL decrease at week 2 was observed to be significantly lower even after week 2 than in patients with < 2 g / dL decrease ( P < 0 . 01 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A significant relationship was observed between the rate of reduction of hemoglobin concentrations at week 2 and the severity of anemia ( P < 0 . 01 ) .
### Output Text: | A significant relationship was observed between the rate of reduction of hemoglobin concentrations at week 2 and the severity of anemia ( P < 0 . 01 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Such factors as sex ( female ) , age ( > or = 60 years old ) , and the ribavirin dose by body weight ( 12 mg / kg or more ) were significant by univariate analysis .
### Output Text: | Such factors as sex ( female ) , age ( > or = 60 years old ) , and the <span class="chemical">ribavirin</span> dose by body weight ( 12 mg / kg or more ) were significant by univariate analysis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSIONS : Careful administration is necessary in patients > or = 60 years old , in female patients , and in patients receiving a ribavirin dose of 12 mg / kg or more .
### Output Text: | CONCLUSIONS : Careful administration is necessary in patients > or = 60 years old , in female patients , and in patients receiving a <span class="chemical">ribavirin</span> dose of 12 mg / kg or more . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Patients who experience a fall in hemoglobin concentrations of 2 g / dL or more at week 2 after the start of treatment should be monitored with particular care .
### Output Text: | Patients who experience a fall in hemoglobin concentrations of 2 g / dL or more at week 2 after the start of treatment should be monitored with particular care . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Zidovudine - induced hepatitis .
### Output Text: | <span class="chemical">Zidovudine</span> - induced hepatitis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A case of acute hepatitis induced by zidovudine in a 38 - year - old patient with AIDS is presented .
### Output Text: | A case of acute hepatitis induced by <span class="chemical">zidovudine</span> in a 38 - year - old patient with AIDS is presented . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The mechanism whereby the hepatitis was induced is not known .
### Output Text: | The mechanism whereby the hepatitis was induced is not known . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: However , the patient tolerated well an alternative reverse transcriptase inhibitor , 2 ' 3 ' dideoxyinosine .
### Output Text: | However , the patient tolerated well an alternative reverse transcriptase inhibitor , <span class="chemical">2 ' 3 ' dideoxyinosine</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Physicians caring for patients with AIDS should be aware of this hitherto rarely reported complication .
### Output Text: | Physicians caring for patients with AIDS should be aware of this hitherto rarely reported complication . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Oxidative damage precedes nitrative damage in adriamycin - induced cardiac mitochondrial injury .
### Output Text: | Oxidative damage precedes nitrative damage in <span class="chemical">adriamycin</span> - induced cardiac mitochondrial injury . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The purpose of the present study was to determine if elevated reactive oxygen ( ROS ) / nitrogen species ( RNS ) reported to be present in adriamycin ( ADR ) - induced cardiotoxicity actually resulted in cardiomyocyte oxidative / nitrative damage , and to quantitatively determine the time course and subcellular localization of these postulated damage products using an in vivo approach .
### Output Text: | The purpose of the present study was to determine if elevated reactive <span class="chemical">oxygen</span> ( ROS ) / <span class="chemical">nitrogen</span> species ( RNS ) reported to be present in <span class="chemical">adriamycin</span> ( <span class="chemical">ADR</span> ) - induced cardiotoxicity actually resulted in cardiomyocyte oxidative / nitrative damage , and to quantitatively determine the time course and subcellular localization of these postulated damage products using an in vivo approach . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: B6C3 mice were treated with a single dose of 20 mg / kg ADR .
### Output Text: | B6C3 mice were treated with a single dose of 20 mg / kg <span class="chemical">ADR</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Ultrastructural damage and levels of 4 - hydroxy - 2 - nonenal ( 4HNE ) - protein adducts and 3 - nitrotyrosine ( 3NT ) were analyzed .
### Output Text: | Ultrastructural damage and levels of <span class="chemical">4 - hydroxy - 2 - nonenal</span> ( <span class="chemical">4HNE</span> ) - protein adducts and <span class="chemical">3 - nitrotyrosine</span> ( <span class="chemical">3NT</span> ) were analyzed . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Quantitative ultrastructural damage using computerized image techniques showed cardiomyocyte injury as early as 3 hours , with mitochondria being the most extensively and progressively injured subcellular organelle .
### Output Text: | Quantitative ultrastructural damage using computerized image techniques showed cardiomyocyte injury as early as 3 hours , with mitochondria being the most extensively and progressively injured subcellular organelle . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Analysis of 4HNE protein adducts by immunogold electron microscopy showed appearance of 4HNE protein adducts in mitochondria as early as 3 hours , with a peak at 6 hours and subsequent decline at 24 hours .
### Output Text: | Analysis of <span class="chemical">4HNE</span> protein adducts by immunogold electron microscopy showed appearance of <span class="chemical">4HNE</span> protein adducts in mitochondria as early as 3 hours , with a peak at 6 hours and subsequent decline at 24 hours . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: 3NT levels were significantly increased in all subcellular compartments at 6 hours and subsequently declined at 24 hours .
### Output Text: | <span class="chemical">3NT</span> levels were significantly increased in all subcellular compartments at 6 hours and subsequently declined at 24 hours . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Our data showed ADR induced 4HNE - protein adducts in mitochondria at the same time point as when mitochondrial injury initially appeared .
### Output Text: | Our data showed <span class="chemical">ADR</span> induced <span class="chemical">4HNE</span> - protein adducts in mitochondria at the same time point as when mitochondrial injury initially appeared . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: These results document for the first time in vivo that mitochondrial oxidative damage precedes nitrative damage .
### Output Text: | These results document for the first time in vivo that mitochondrial oxidative damage precedes nitrative damage . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The progressive nature of mitochondrial injury suggests that mitochondria , not other subcellular organelles , are the major site of intracellular injury .
### Output Text: | The progressive nature of mitochondrial injury suggests that mitochondria , not other subcellular organelles , are the major site of intracellular injury . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Sotalol - induced coronary spasm in a patient with dilated cardiomyopathy associated with sustained ventricular tachycardia .
### Output Text: | <span class="chemical">Sotalol</span> - induced coronary spasm in a patient with dilated cardiomyopathy associated with sustained ventricular tachycardia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A 54 - year - old man with severe left ventricular dysfunction due to dilated cardiomyopathy was referred to our hospital for symptomatic incessant sustained ventricular tachycardia ( VT ) .
### Output Text: | A 54 - year - old man with severe left ventricular dysfunction due to dilated cardiomyopathy was referred to our hospital for symptomatic incessant sustained ventricular tachycardia ( VT ) . |
Subsets and Splits