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In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: These findings indicate that GTN has a reduced efficacy and tolerability by comparison with DCF in the treatment of primary dysmenorrhea .
### Output Text: | These findings indicate that <span class="chemical">GTN</span> has a reduced efficacy and tolerability by comparison with <span class="chemical">DCF</span> in the treatment of primary dysmenorrhea . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Temocapril , a long - acting non - SH group angiotensin converting enzyme inhibitor , modulates glomerular injury in chronic puromycin aminonucleoside nephrosis .
### Output Text: | <span class="chemical">Temocapril</span> , a long - acting non - SH group <span class="chemical">angiotensin</span> converting enzyme inhibitor , modulates glomerular injury in chronic <span class="chemical">puromycin aminonucleoside</span> nephrosis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The purpose of the present study was to determine whether chronic administration of temocapril , a long - acting non - SH group angiotensin converting enzyme ( ACE ) inhibitor , reduced proteinuria , inhibited glomerular hypertrophy and prevented glomerulosclerosis in chronic puromycin aminonucleoside ( PAN ) - induced nephrotic rats .
### Output Text: | The purpose of the present study was to determine whether chronic administration of <span class="chemical">temocapril</span> , a long - acting non - SH group <span class="chemical">angiotensin</span> converting enzyme ( ACE ) inhibitor , reduced proteinuria , inhibited glomerular hypertrophy and prevented glomerulosclerosis in chronic <span class="chemical">puromycin aminonucleoside</span> ( <span class="chemical">PAN</span> ) - induced nephrotic rats . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Nephrosis was induced by injection of PAN ( 15mg / 100g body weight ) in male Sprague - Dawley ( SD ) rats .
### Output Text: | Nephrosis was induced by injection of <span class="chemical">PAN</span> ( 15mg / 100g body weight ) in male Sprague - Dawley ( SD ) rats . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Four groups were used , i ) the PAN group ( 14 ) , ii ) PAN / temocapril ( 13 ) , iii ) temocapril ( 14 ) and iv ) untreated controls ( 15 ) .
### Output Text: | Four groups were used , i ) the <span class="chemical">PAN</span> group ( 14 ) , ii ) <span class="chemical">PAN</span> / <span class="chemical">temocapril</span> ( 13 ) , iii ) <span class="chemical">temocapril</span> ( 14 ) and iv ) untreated controls ( 15 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Temocapril ( 8 mg / kg / day ) was administered to the rats which were killed at weeks 4 , 14 or 20 .
### Output Text: | <span class="chemical">Temocapril</span> ( 8 mg / kg / day ) was administered to the rats which were killed at weeks 4 , 14 or 20 . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: At each time point , systolic blood pressure ( BP ) , urinary protein excretion and renal histopathological findings were evaluated , and morphometric image analysis was done .
### Output Text: | At each time point , systolic blood pressure ( BP ) , urinary protein excretion and renal histopathological findings were evaluated , and morphometric image analysis was done . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Systolic BP in the PAN group was significantly high at 4 , 14 and 20 weeks , but was normal in the PAN / temocapril group .
### Output Text: | Systolic BP in the <span class="chemical">PAN</span> group was significantly high at 4 , 14 and 20 weeks , but was normal in the <span class="chemical">PAN</span> / <span class="chemical">temocapril</span> group . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Urinary protein excretion in the PAN group increased significantly , peaking at 8 days , then decreased at 4 weeks , but rose again significantly at 14 and 20 weeks .
### Output Text: | Urinary protein excretion in the <span class="chemical">PAN</span> group increased significantly , peaking at 8 days , then decreased at 4 weeks , but rose again significantly at 14 and 20 weeks . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Temocapril did not attenuate proteinuria at 8 days , but it did markedly lower it from weeks 4 to 20 .
### Output Text: | <span class="chemical">Temocapril</span> did not attenuate proteinuria at 8 days , but it did markedly lower it from weeks 4 to 20 . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The glomerulosclerosis index ( GSI ) was 6 . 21 % at 4 weeks and respectively 25 . 35 % and 30 . 49 % at 14 and 20 weeks in the PAN group .
### Output Text: | The glomerulosclerosis index ( GSI ) was 6 . 21 % at 4 weeks and respectively 25 . 35 % and 30 . 49 % at 14 and 20 weeks in the <span class="chemical">PAN</span> group . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: There was a significant correlation between urinary protein excretion and GSI ( r = 0 . 808 , p < 0 . 0001 ) .
### Output Text: | There was a significant correlation between urinary protein excretion and GSI ( r = 0 . 808 , p < 0 . 0001 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The ratio of glomerular tuft area to the area of Bowman ' s capsules ( GT / BC ) in the PAN group was significantly increased , but it was significantly lower in the PAN / temocapril group .
### Output Text: | The ratio of glomerular tuft area to the area of Bowman ' s capsules ( GT / BC ) in the <span class="chemical">PAN</span> group was significantly increased , but it was significantly lower in the <span class="chemical">PAN</span> / <span class="chemical">temocapril</span> group . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: It appears that temocapril was effective in retarding renal progression and protected renal function in PAN neprotic rats .
### Output Text: | It appears that <span class="chemical">temocapril</span> was effective in retarding renal progression and protected renal function in <span class="chemical">PAN</span> neprotic rats . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Pulmonary hypertension after ibuprofen prophylaxis in very preterm infants .
### Output Text: | Pulmonary hypertension after <span class="chemical">ibuprofen</span> prophylaxis in very preterm infants . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We report three cases of severe hypoxaemia after ibuprofen administration during a randomised controlled trial of prophylactic treatment of patent ductus arteriosus with ibuprofen in premature infants born at less than 28 weeks of gestation .
### Output Text: | We report three cases of severe hypoxaemia after <span class="chemical">ibuprofen</span> administration during a randomised controlled trial of prophylactic treatment of patent ductus arteriosus with <span class="chemical">ibuprofen</span> in premature infants born at less than 28 weeks of gestation . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Echocardiography showed severely decreased pulmonary blood flow .
### Output Text: | Echocardiography showed severely decreased pulmonary blood flow . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Hypoxaemia resolved quickly on inhaled nitric oxide therapy .
### Output Text: | Hypoxaemia resolved quickly on inhaled <span class="chemical">nitric oxide</span> therapy . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We suggest that investigators involved in similar trials pay close attention to pulmonary pressure if hypoxaemia occurs after prophylactic administration of ibuprofen .
### Output Text: | We suggest that investigators involved in similar trials pay close attention to pulmonary pressure if hypoxaemia occurs after prophylactic administration of <span class="chemical">ibuprofen</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Hyponatremia and syndrome of inappropriate anti - diuretic hormone reported with the use of Vincristine : an over - representation of Asians ?
### Output Text: | Hyponatremia and syndrome of inappropriate anti - diuretic hormone reported with the use of <span class="chemical">Vincristine</span> : an over - representation of Asians ? |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: PURPOSE : This retrospective study used a pharmaceutical company ' s global safety database to determine the reporting rate of hyponatremia and / or syndrome of inappropriate secretion of anti - diuretic hormone ( SIADH ) among vincristine - treated patients and to explore the possibility of at - risk population subgroups .
### Output Text: | PURPOSE : This retrospective study used a pharmaceutical company ' s global safety database to determine the reporting rate of hyponatremia and / or syndrome of inappropriate secretion of anti - diuretic hormone ( SIADH ) among <span class="chemical">vincristine</span> - treated patients and to explore the possibility of at - risk population subgroups . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: METHOD : We searched the Eli Lilly and Company ' s computerized adverse event database for all reported cases of hyponatremia and / or SIADH as of 1 November 1999 that had been reported during the use of vincristine .
### Output Text: | METHOD : We searched the Eli Lilly and Company ' s computerized adverse event database for all reported cases of hyponatremia and / or SIADH as of 1 November 1999 that had been reported during the use of <span class="chemical">vincristine</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: RESULTS : A total of 76 cases of hyponatremia and / or SIADH associated with vincristine use were identified .
### Output Text: | RESULTS : A total of 76 cases of hyponatremia and / or SIADH associated with <span class="chemical">vincristine</span> use were identified . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The overall reporting rate was estimated to be 1 . 3 / 100 , 000 treated patients .
### Output Text: | The overall reporting rate was estimated to be 1 . 3 / 100 , 000 treated patients . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The average age of patients was 35 . 6 + / - 28 . 3 years , and 62 % were males .
### Output Text: | The average age of patients was 35 . 6 + / - 28 . 3 years , and 62 % were males . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Approximately 75 % of the patients were receiving treatment for leukemia or lymphoma .
### Output Text: | Approximately 75 % of the patients were receiving treatment for leukemia or lymphoma . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Among the 39 reports that included information on race , the racial distribution was : 1 Black , 3 Caucasian , and 35 Asian .
### Output Text: | Among the 39 reports that included information on race , the racial distribution was : 1 Black , 3 Caucasian , and 35 Asian . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSION : Our data suggest that Asian patients may be at increased risk of hyponatremia and / or SIADH associated with vincristine use .
### Output Text: | CONCLUSION : Our data suggest that Asian patients may be at increased risk of hyponatremia and / or SIADH associated with <span class="chemical">vincristine</span> use . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Although the overall reported rate of SIADH associated with vincristine is very low , physicians caring for Asian oncology patients should be aware of this potential serious but reversible adverse event .
### Output Text: | Although the overall reported rate of SIADH associated with <span class="chemical">vincristine</span> is very low , physicians caring for Asian oncology patients should be aware of this potential serious but reversible adverse event . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Delayed toxicity of cyclophosphamide on the bladder of DBA / 2 and C57BL / 6 female mouse .
### Output Text: | Delayed toxicity of <span class="chemical">cyclophosphamide</span> on the bladder of DBA / 2 and C57BL / 6 female mouse . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The present study describes the delayed development of a severe bladder pathology in a susceptible strain of mice ( DBA / 2 ) but not in a resistant strain ( C57BL / 6 ) when both were treated with a single 300 mg / kg dose of cyclophosphamide ( CY ) .
### Output Text: | The present study describes the delayed development of a severe bladder pathology in a susceptible strain of mice ( DBA / 2 ) but not in a resistant strain ( C57BL / 6 ) when both were treated with a single 300 mg / kg dose of <span class="chemical">cyclophosphamide</span> ( <span class="chemical">CY</span> ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Inbred DBA / 2 and C57BL / 6 female mice were injected with CY , and the effect of the drug on the bladder was assessed during 100 days by light microscopy using different staining procedures , and after 30 days by conventional electron microscopy .
### Output Text: | Inbred DBA / 2 and C57BL / 6 female mice were injected with <span class="chemical">CY</span> , and the effect of the drug on the bladder was assessed during 100 days by light microscopy using different staining procedures , and after 30 days by conventional electron microscopy . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Early CY toxicity caused a typical haemorrhagic cystitis in both strains that was completely repaired in about 7 - 10 days .
### Output Text: | Early <span class="chemical">CY</span> toxicity caused a typical haemorrhagic cystitis in both strains that was completely repaired in about 7 - 10 days . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: After 30 days of CY injection ulcerous and non - ulcerous forms of chronic cystitis appeared in 86 % of DBA / 2 mice but only in 4 % of C57BL / 6 mice .
### Output Text: | After 30 days of <span class="chemical">CY</span> injection ulcerous and non - ulcerous forms of chronic cystitis appeared in 86 % of DBA / 2 mice but only in 4 % of C57BL / 6 mice . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Delayed cystitis was characterized by infiltration and transepithelial passage into the lumen of inflammatory cells and by frequent exfoliation of the urothelium .
### Output Text: | Delayed cystitis was characterized by infiltration and transepithelial passage into the lumen of inflammatory cells and by frequent exfoliation of the urothelium . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Mast cells appeared in the connective and muscular layers of the bladder at a much higher number in DBA / 2 mice than in C57BL / 6 mice or untreated controls .
### Output Text: | Mast cells appeared in the connective and muscular layers of the bladder at a much higher number in DBA / 2 mice than in C57BL / 6 mice or untreated controls . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Electron microscopy disclosed the absence of the typical discoidal vesicles normally present in the cytoplasm of surface cells .
### Output Text: | Electron microscopy disclosed the absence of the typical discoidal vesicles normally present in the cytoplasm of surface cells . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Instead , numerous abnormal vesicles containing one or several dark granules were observed in the cytoplasm of cells from all the epithelial layers .
### Output Text: | Instead , numerous abnormal vesicles containing one or several dark granules were observed in the cytoplasm of cells from all the epithelial layers . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Delayed cystitis still persisted in DBA / 2 mice 100 days after treatment .
### Output Text: | Delayed cystitis still persisted in DBA / 2 mice 100 days after treatment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: These results indicate that delayed toxicity of CY in female DBA / 2 mice causes a bladder pathology that is not observed in C57BL / 6 mice .
### Output Text: | These results indicate that delayed toxicity of <span class="chemical">CY</span> in female DBA / 2 mice causes a bladder pathology that is not observed in C57BL / 6 mice . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: This pathology resembles interstitial cystitis in humans and could perhaps be used as an animal model for studies on the disease .
### Output Text: | This pathology resembles interstitial cystitis in humans and could perhaps be used as an animal model for studies on the disease . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: High - dose 5 - fluorouracil / folinic acid in combination with three - weekly mitomycin C in the treatment of advanced gastric cancer .
### Output Text: | High - dose <span class="chemical">5 - fluorouracil</span> / <span class="chemical">folinic acid</span> in combination with three - weekly <span class="chemical">mitomycin C</span> in the treatment of advanced gastric cancer . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: A phase II study .
### Output Text: | A phase II study . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: BACKGROUND : The 24 - hour continuous infusion of 5 - fluorouracil ( 5 - FU ) and folinic acid ( FA ) as part of several new multidrug chemotherapy regimens in advanced gastric cancer ( AGC ) has shown to be effective , with low toxicity .
### Output Text: | BACKGROUND : The 24 - hour continuous infusion of <span class="chemical">5 - fluorouracil</span> ( <span class="chemical">5 - FU</span> ) and <span class="chemical">folinic acid</span> ( <span class="chemical">FA</span> ) as part of several new multidrug chemotherapy regimens in advanced gastric cancer ( AGC ) has shown to be effective , with low toxicity . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: In a previous phase II study with 3 - weekly bolus 5 - FU , FA and mitomycin C ( MMC ) we found a low toxicity rate and response rates comparable to those of regimens such as ELF , FAM or FAMTX , and a promising median overall survival .
### Output Text: | In a previous phase II study with 3 - weekly bolus <span class="chemical">5 - FU</span> , <span class="chemical">FA</span> and <span class="chemical">mitomycin C</span> ( <span class="chemical">MMC</span> ) we found a low toxicity rate and response rates comparable to those of regimens such as ELF , FAM or FAMTX , and a promising median overall survival . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: In order to improve this MMC - dependent schedule we initiated a phase II study with high - dose 5 - FU / FA and 3 - weekly bolus MMC .
### Output Text: | In order to improve this <span class="chemical">MMC</span> - dependent schedule we initiated a phase II study with high - dose <span class="chemical">5 - FU</span> / <span class="chemical">FA</span> and 3 - weekly bolus <span class="chemical">MMC</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: PATIENTS AND METHODS : From February , 1998 to September , 2000 we recruited 33 patients with AGC to receive weekly 24 - hour 5 - FU 2 , 600 mg / m ( 2 ) preceded by 2 - hour FA 500 mg / m ( 2 ) for 6 weeks , followed by a 2 - week rest period .
### Output Text: | PATIENTS AND METHODS : From February , 1998 to September , 2000 we recruited 33 patients with AGC to receive weekly 24 - hour <span class="chemical">5 - FU</span> 2 , 600 mg / m ( 2 ) preceded by 2 - hour <span class="chemical">FA</span> 500 mg / m ( 2 ) for 6 weeks , followed by a 2 - week rest period . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Bolus MMC 10 mg / m ( 2 ) was added in 3 - weekly intervals .
### Output Text: | Bolus <span class="chemical">MMC</span> 10 mg / m ( 2 ) was added in 3 - weekly intervals . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Treatment given on an outpatient basis , using portable pump systems , was repeated on day 57 .
### Output Text: | Treatment given on an outpatient basis , using portable pump systems , was repeated on day 57 . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Patients ' characteristics were : male / female ratio 20 / 13 ; median age 57 ( 27 - 75 ) years ; median WHO status 1 ( 0 - 2 ) .
### Output Text: | Patients ' characteristics were : male / female ratio 20 / 13 ; median age 57 ( 27 - 75 ) years ; median WHO status 1 ( 0 - 2 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: 18 patients had a primary AGC , and 15 showed a relapsed AGC .
### Output Text: | 18 patients had a primary AGC , and 15 showed a relapsed AGC . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Median follow - up was 11 . 8 months ( range of those surviving : 2 . 7 - 11 . 8 months ) .
### Output Text: | Median follow - up was 11 . 8 months ( range of those surviving : 2 . 7 - 11 . 8 months ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: RESULTS : 32 patients were evaluable for response - complete remission 9 . 1 % ( n = 3 ) , partial remission 45 . 5 % ( n = 15 ) , no change 27 . 3 % ( n = 9 ) , progressive disease 15 . 1 % ( n = 5 ) .
### Output Text: | RESULTS : 32 patients were evaluable for response - complete remission 9 . 1 % ( n = 3 ) , partial remission 45 . 5 % ( n = 15 ) , no change 27 . 3 % ( n = 9 ) , progressive disease 15 . 1 % ( n = 5 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Median overall survival time was 10 . 2 months [ 95 % confidence interval ( CI ) : 8 . 7 - 11 . 6 ] , and median progression - free survival time was 7 . 6 months ( 95 % CI : 4 . 4 - 10 . 9 ) .
### Output Text: | Median overall survival time was 10 . 2 months [ 95 % confidence interval ( CI ) : 8 . 7 - 11 . 6 ] , and median progression - free survival time was 7 . 6 months ( 95 % CI : 4 . 4 - 10 . 9 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The worst toxicities ( % ) observed were ( CTC - NCI 1 / 2 / 3 ) : leukopenia 45 . 5 / 18 . 2 / 6 . 1 , thrombocytopenia 33 . 3 / 9 . 1 / 6 . 1 , vomitus 24 . 2 / 9 . 1 / 0 , diarrhea 36 . 4 / 6 . 1 / 3 . 0 , stomatitis 18 . 2 / 9 . 1 / 0 , hand - foot syndrome 12 . 1 / 0 / 0 .
### Output Text: | The worst toxicities ( % ) observed were ( CTC - NCI 1 / 2 / 3 ) : leukopenia 45 . 5 / 18 . 2 / 6 . 1 , thrombocytopenia 33 . 3 / 9 . 1 / 6 . 1 , vomitus 24 . 2 / 9 . 1 / 0 , diarrhea 36 . 4 / 6 . 1 / 3 . 0 , stomatitis 18 . 2 / 9 . 1 / 0 , hand - foot syndrome 12 . 1 / 0 / 0 . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Two patients developed hemolytic - uremic syndrome ( HUS ) .
### Output Text: | Two patients developed hemolytic - uremic syndrome ( HUS ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSIONS : High - dose 5 - FU / FA / MMC is an effective and well - tolerated outpatient regimen for AGC ( objective response rate 54 . 6 % ) .
### Output Text: | CONCLUSIONS : High - dose <span class="chemical">5 - FU</span> / <span class="chemical">FA</span> / <span class="chemical">MMC</span> is an effective and well - tolerated outpatient regimen for AGC ( objective response rate 54 . 6 % ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: It may serve as an alternative to cisplatin - containing regimens ; however , it has to be considered that possibly HUS may occur .
### Output Text: | It may serve as an alternative to <span class="chemical">cisplatin</span> - containing regimens ; however , it has to be considered that possibly HUS may occur . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Persistent sterile leukocyturia is associated with impaired renal function in human immunodeficiency virus type 1 - infected children treated with indinavir .
### Output Text: | Persistent sterile leukocyturia is associated with impaired renal function in human immunodeficiency virus type 1 - infected children treated with <span class="chemical">indinavir</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: BACKGROUND : Prolonged administration of indinavir is associated with the occurrence of a variety of renal complications in adults .
### Output Text: | BACKGROUND : Prolonged administration of <span class="chemical">indinavir</span> is associated with the occurrence of a variety of renal complications in adults . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: These well - documented side effects have restricted the use of this potent protease inhibitor in children .
### Output Text: | These well - documented side effects have restricted the use of this potent protease inhibitor in children . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: DESIGN : A prospective study to monitor indinavir - related nephrotoxicity in a cohort of 30 human immunodeficiency virus type 1 - infected children treated with indinavir .
### Output Text: | DESIGN : A prospective study to monitor <span class="chemical">indinavir</span> - related nephrotoxicity in a cohort of 30 human immunodeficiency virus type 1 - infected children treated with <span class="chemical">indinavir</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: METHODS : Urinary pH , albumin , creatinine , the presence of erythrocytes , leukocytes , bacteria and crystals , and culture were analyzed every 3 months for 96 weeks .
### Output Text: | METHODS : Urinary pH , albumin , <span class="chemical">creatinine</span> , the presence of erythrocytes , leukocytes , bacteria and crystals , and culture were analyzed every 3 months for 96 weeks . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Serum creatinine levels were routinely determined at the same time points .
### Output Text: | Serum <span class="chemical">creatinine</span> levels were routinely determined at the same time points . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Steady - state pharmacokinetics of indinavir were done at week 4 after the initiation of indinavir .
### Output Text: | Steady - state pharmacokinetics of <span class="chemical">indinavir</span> were done at week 4 after the initiation of <span class="chemical">indinavir</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: RESULTS : The cumulative incidence of persistent sterile leukocyturia ( > or = 75 cells / micro L in at least 2 consecutive visits ) after 96 weeks was 53 % .
### Output Text: | RESULTS : The cumulative incidence of persistent sterile leukocyturia ( > or = 75 cells / micro L in at least 2 consecutive visits ) after 96 weeks was 53 % . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Persistent sterile leukocyturia was frequently associated with a mild increase in the urine albumin / creatinine ratio and by microscopic hematuria .
### Output Text: | Persistent sterile leukocyturia was frequently associated with a mild increase in the urine albumin / <span class="chemical">creatinine</span> ratio and by microscopic hematuria . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The cumulative incidence of serum creatinine levels > 50 % above normal was 33 % after 96 weeks .
### Output Text: | The cumulative incidence of serum <span class="chemical">creatinine</span> levels > 50 % above normal was 33 % after 96 weeks . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Children with persistent sterile leukocyturia more frequently had serum creatinine levels of 50 % above normal than those children without persistent sterile leukocyturia .
### Output Text: | Children with persistent sterile leukocyturia more frequently had serum <span class="chemical">creatinine</span> levels of 50 % above normal than those children without persistent sterile leukocyturia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: In children younger than 5 . 6 years , persistent sterile leukocyturia was significantly more frequent than in older children .
### Output Text: | In children younger than 5 . 6 years , persistent sterile leukocyturia was significantly more frequent than in older children . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A higher cumulative incidence of persistent leukocyturia was found in children with an area under the curve > 19 mg / L x h or a peak serum level of indinavir > 12 mg / L .
### Output Text: | A higher cumulative incidence of persistent leukocyturia was found in children with an area under the curve > 19 mg / L x h or a peak serum level of <span class="chemical">indinavir</span> > 12 mg / L . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: In 4 children , indinavir was discontinued because of nephrotoxicity .
### Output Text: | In 4 children , <span class="chemical">indinavir</span> was discontinued because of nephrotoxicity . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Subsequently , the serum creatinine levels decreased , the urine albumin / creatinine ratios returned to zero , and the leukocyturia disappeared within 3 months .
### Output Text: | Subsequently , the serum <span class="chemical">creatinine</span> levels decreased , the urine albumin / <span class="chemical">creatinine</span> ratios returned to zero , and the leukocyturia disappeared within 3 months . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSIONS : Children treated with indinavir have a high cumulative incidence of persistent sterile leukocyturia .
### Output Text: | CONCLUSIONS : Children treated with <span class="chemical">indinavir</span> have a high cumulative incidence of persistent sterile leukocyturia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Children with persistent sterile leukocyturia more frequently had an increase in serum creatinine levels of > 50 % above normal .
### Output Text: | Children with persistent sterile leukocyturia more frequently had an increase in serum <span class="chemical">creatinine</span> levels of > 50 % above normal . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Younger children have an additional risk for renal complications .
### Output Text: | Younger children have an additional risk for renal complications . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The impairment of the renal function in these children occurred in the absence of clinical symptoms of nephrolithiasis .
### Output Text: | The impairment of the renal function in these children occurred in the absence of clinical symptoms of nephrolithiasis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Indinavir - associated nephrotoxicity must be monitored closely , especially in children with risk factors such as persistent sterile leukocyturia , age < 5 . 6 years , an area under the curve of indinavir > 19 mg / L x h , and a C ( max ) > 12 mg / L .
### Output Text: | <span class="chemical">Indinavir</span> - associated nephrotoxicity must be monitored closely , especially in children with risk factors such as persistent sterile leukocyturia , age < 5 . 6 years , an area under the curve of <span class="chemical">indinavir</span> > 19 mg / L x h , and a C ( max ) > 12 mg / L . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Utility of troponin I in patients with cocaine - associated chest pain .
### Output Text: | Utility of troponin I in patients with <span class="chemical">cocaine</span> - associated chest pain . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Baseline electrocardiogram abnormalities and market elevations not associated with myocardial necrosis make accurate diagnosis of myocardial infarction ( MI ) difficult in patients with cocaine - associated chest pain .
### Output Text: | Baseline electrocardiogram abnormalities and market elevations not associated with myocardial necrosis make accurate diagnosis of myocardial infarction ( MI ) difficult in patients with <span class="chemical">cocaine</span> - associated chest pain . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Troponin sampling may offer greater diagnostic utility in these patients .
### Output Text: | Troponin sampling may offer greater diagnostic utility in these patients . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: OBJECTIVE : To assess outcomes based on troponin positivity in patients with cocaine chest pain admitted for exclusion of MI .
### Output Text: | OBJECTIVE : To assess outcomes based on troponin positivity in patients with <span class="chemical">cocaine</span> chest pain admitted for exclusion of MI . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: METHODS : Outcomes were examined in patients admitted for possible MI after cocaine use .
### Output Text: | METHODS : Outcomes were examined in patients admitted for possible MI after <span class="chemical">cocaine</span> use . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: All patients underwent a rapid rule - in protocol that included serial sampling of creatine kinase ( CK ) , CK - MB , and cardiac troponin I ( cTnI ) over eight hours .
### Output Text: | All patients underwent a rapid rule - in protocol that included serial sampling of <span class="chemical">creatine</span> kinase ( CK ) , CK - MB , and cardiac troponin I ( cTnI ) over eight hours . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Outcomes included CK - MB MI ( CK - MB > or = 8 ng / mL with a relative index [ ( CK - MB x 100 ) / total CK ] > or = 4 , cardiac death , and significant coronary disease ( > or = 50 % ) .
### Output Text: | Outcomes included CK - MB MI ( CK - MB > or = 8 ng / mL with a relative index [ ( CK - MB x 100 ) / total CK ] > or = 4 , cardiac death , and significant coronary disease ( > or = 50 % ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: RESULTS : Of the 246 admitted patients , 34 ( 14 % ) met CK - MB criteria for MI and 38 ( 16 % ) had cTnI elevations .
### Output Text: | RESULTS : Of the 246 admitted patients , 34 ( 14 % ) met CK - MB criteria for MI and 38 ( 16 % ) had cTnI elevations . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Angiography was performed in 29 of 38 patients who were cTnI - positive , with significant disease present in 25 ( 86 % ) .
### Output Text: | Angiography was performed in 29 of 38 patients who were cTnI - positive , with significant disease present in 25 ( 86 % ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Three of the four patients without significant disease who had cTnI elevations met CK - MB criteria for MI , and the other had a peak CK - MB level of 13 ng / mL .
### Output Text: | Three of the four patients without significant disease who had cTnI elevations met CK - MB criteria for MI , and the other had a peak CK - MB level of 13 ng / mL . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Sensitivities , specificities , and positive and negative likelihood ratios for predicting cardiac death or significant disease were high for both CK - MB MI and cTnI and were not significantly different .
### Output Text: | Sensitivities , specificities , and positive and negative likelihood ratios for predicting cardiac death or significant disease were high for both CK - MB MI and cTnI and were not significantly different . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSIONS : Most patients with cTnI elevations meet CK - MB criteria for MI , as well as have a high incidence of underlying significant disease .
### Output Text: | CONCLUSIONS : Most patients with cTnI elevations meet CK - MB criteria for MI , as well as have a high incidence of underlying significant disease . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Troponin appears to have an equivalent diagnostic accuracy compared with CK - MB for diagnosing necrosis in patients with cocaine - associated chest pain and suspected MI .
### Output Text: | Troponin appears to have an equivalent diagnostic accuracy compared with CK - MB for diagnosing necrosis in patients with <span class="chemical">cocaine</span> - associated chest pain and suspected MI . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Acute interstitial nephritis due to nicergoline ( Sermion ) .
### Output Text: | Acute interstitial nephritis due to <span class="chemical">nicergoline</span> ( <span class="chemical">Sermion</span> ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We report a case of acute interstitial nephritis ( AIN ) due to nicergoline ( Sermion ) .
### Output Text: | We report a case of acute interstitial nephritis ( AIN ) due to <span class="chemical">nicergoline</span> ( <span class="chemical">Sermion</span> ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A 50 - year - old patient admitted to our hospital for fever and acute renal failure .
### Output Text: | A 50 - year - old patient admitted to our hospital for fever and acute renal failure . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Before admission , he had been taking nicergoline and bendazac lysine due to retinal vein occlusion at ophthalmologic department .
### Output Text: | Before admission , he had been taking <span class="chemical">nicergoline</span> and <span class="chemical">bendazac lysine</span> due to retinal vein occlusion at ophthalmologic department . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Thereafter , he experienced intermittent fever and skin rash .
### Output Text: | Thereafter , he experienced intermittent fever and skin rash . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: On admission , clinical symptoms ( i . e . arthralgia and fever ) and laboratory findings ( i . e . eosinophilia and renal failure ) suggested AIN , and which was confirmed by pathologic findings on renal biopsy .
### Output Text: | On admission , clinical symptoms ( i . e . arthralgia and fever ) and laboratory findings ( i . e . eosinophilia and renal failure ) suggested AIN , and which was confirmed by pathologic findings on renal biopsy . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: A lymphocyte transformation test demonstrated a positive result against nicergoline .
### Output Text: | A lymphocyte transformation test demonstrated a positive result against <span class="chemical">nicergoline</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Treatment was consisted of withdrawal of nicergoline and intravenous methylprednisolone , and his renal function was completely recovered .
### Output Text: | Treatment was consisted of withdrawal of <span class="chemical">nicergoline</span> and intravenous <span class="chemical">methylprednisolone</span> , and his renal function was completely recovered . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: To our knowledge , this is the first report of nicergoline - associated AIN .
### Output Text: | To our knowledge , this is the first report of <span class="chemical">nicergoline</span> - associated AIN . |
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