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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Median age of the 220 cases since 2015 is 2.5 years (2.5 years in intensive care cases), 94% were hospitalised, 17% (n\xa0=\xa038) in intensive care. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Further assessment was done via Quantitative Analgesic Questionnaire (QAQ) regarding the analgesics taken. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Radiographic scoring at each time interval showed reduction in both number of nodules (P = \u200a<0.0001) and largest nodule diameter (P =\u200a <0.0001) in all patients for at least 18 months following B cell depletion. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Eating competent individuals (37%, classified by ecSI 2.0TM) had a better quality of diet (p < 0.05 for all). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We conducted a secondary analysis of neuropsychological outcomes to evaluate whether progesterone is associated with improved recovery of cognitive and motor functioning. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Cardiorenal Syndrome Type 5 (CRS Type 5) reflects concomitant cardiac and renal dysfunctions in the setting of a wide spectrum of systemic disorders. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Findings have public health implications for India and suggest that caution should be taken when translating evidence across countries. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Usually candidate genes are identified according to a gene-by-gene comparison of expression. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The most common procedure was lobectomy (48%). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In stepwise multivariate linear regression analysis, blood HIV-1 RNA level (p<0.0001) was most strongly associated with seminal plasma HIV-1 RNA level. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Similarly, both rs3803300 GG genotype and G allele had obvious differences between case and control groups (P\u200a<\u200a.05) and it was closely associated with CHD susceptibility. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We performed flow cytometric immunophenotyping in 33 patients with common variable immunodeficiency, 23 with idiopathic primary hypogammaglobulinemia and 21 with IgG subclass deficiency, as well as in 47 asymptomatic first-degree family members of patients and 101 unrelated healthy controls. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Seventy-nine voles (10.78%; n=733) were positive for mycobacteria, with the highest prevalence in spring (13.15%; n=327). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Group 2 consisted of ten patients who, after similar ventral removal and bone interposition, were stabilised by ventral instrumentation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We found significant difference between the groups with respect to both ACE and MTHFR genotype distributions (p< 0.001, p< 0.001 respectively). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In cardiac resynchronization therapy (CRT), left ventricular (LV) pacing is achieved by positioning the LV lead in one of the tributaries of the coronary sinus (CS). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Escherichia coli sequence type 410 (ST410) has been reported worldwide as an extraintestinal pathogen associated with resistance to fluoroquinolones, third-generation cephalosporins, and carbapenems. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Globally, 507 (70.7%) HCSs showed protective antibody titres, and an anamnestic response was observed in more than 95% subjects receiving the booster dose. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Blood samples were drawn from patients with particular restriction for measuring serum aldosteronism, plasma renin activity, and serum potassium. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is unclear whether dietary lutein/zeaxanthin intake in colorectal cancer is associated with microRNA processing involved in DICER1 cleavage for messenger RNA translation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In summary, RTX therapy induces resolution of pulmonary granulomatous inflammation in GPA following prolonged B cell depletion. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Multivariable survival analyses identified carcinoembryonic antigen levels (hazard ratio [HR]\xa0=\xa03.056; 95% confidence interval [CI]\xa0=\xa01.354-6.897; P\xa0=\xa00.007), treatment strategy (HR\xa0=\xa00.212; 95% CI\xa0=\xa00.056-0.808; P\xa0=\xa00.023), and CD133+ CD44+ CD54+ cellular subpopulation of CTCs (HR\xa0=\xa06.459; 95% CI\xa0=\xa01.461-28.558; P\xa0=\xa00.014) as independent prognostic factors for CRC patients with liver metastasis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition, the vaginal and cervical wound infection rates after conization in patients treated with iodoform were significantly lower than the rates in those without iodoform treatment (p<0.05). |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These findings highlight the importance of health promotion to help drivers make better choices about their health behaviors, which are often underpinned by the limitations of their work environment. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A 32-element cardiac coil was used for data acquisition. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Results support the notion that communal living residents may develop more tolerant attitudes by striving toward superordinate community goals (objectives held by (a) the whole group and (b) which individual members could not achieve alone). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, results from high-income countries remain inconsistent, and there has been limited research from low- and middle-income countries. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There was no difference in MCP-1 -2518*G allele frequency between SSc patients and healthy subjects (patients: 0.23; controls: 0.24; P > .05). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We examined associations between the neighborhood availability (vendor density per km2 within 400\u202fm and 1600\u202fm buffers of households) and accessibility (distance from the household to the nearest vendor) of fruit/vegetable and highly processed/take-away food vendors with 11 cardiovascular risk factors, including adiposity measures, glucose-insulin, blood pressure, and lipid profile. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Background It is well known that white matter injuries observed at birth are associated with adverse neurodevelopmental outcomes later in life. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Their average age was 67 (range: 30-96) years and all were thoroughly investigated with a complete physical examination and laboratory tests as well as imaging studies and bone scans. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This retrospective study investigated the correlation between liver tests abnormalities and treatment outcomes in patients with unresectable advanced or metastatic soft tissue sarcomas (STS) treated with trabectedin 1.5 mg/m(2) once every 3 weeks at three reference centers in Italy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This study suggests that stress and parents' education level were associated with atopic dermatitis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is seemly that the optimal blastocyst and frozen blastocyst rates was higher in the low oxygen group, but the data did not reach a statistical significance. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We studied two male (Osteoporotic Fractures in Men Study [MrOS] US, MrOS Sweden) and one female (Study of Osteoporotic Fractures [SOF]) large prospective cohorts of older subjects, looking at BMD, BMD change, and radiographically and/or medically confirmed incident fractures (8067 subjects, 2185 incident nonvertebral or vertebral fractures). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Since 7 June 2018, an enterovirus D-68 (EV-D68) season (the third since 2015) is ongoing in Wales, with 114 confirmed cases thus far. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The modified extract of P. judaica is safe to treat sensitive patients, even at accelerated regimens, and induces significant immunological changes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Elderly non-fallers also demonstrated significant reductions in stride and stance time variability. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A subset of severely burned pediatric subjects from a prospective clinical trial (n = 222) were included in our study (n = 54, 7-18 years, ‚â•30% TBSA burn). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our simulation results show how this algorithm expands the search tree effectively and efficiently in a grid-world environment. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | High levels of circulating TNF and its receptors, TNFR1 and TNFR2, predict the progression of diabetic kidney disease (DKD), but their contribution to organ damage in DKD remains largely unknown. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The 30-day readmission rate was 9.4%. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Over a number of years a stable fusion can be achieved through either operation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Over a 6-year period, 226 cases had both MIF and one of these other methods performed for comparison. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The search process identified a mean of 30% KIR better or best donors; the success ranged from 24% to 38% in the 11 centers enrolling ‚â•8 patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, the incidence of itching was higher in group R (4.3%) than in group N (0.7%) (P\u200a<\u200a0.001). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | B3/H24Rx appears to have evolved by the acquisition of the extended-spectrum β-lactamase (ESBL)-encoding gene blaCTX-M-15 and an IncFII plasmid, encoding IncFIA and IncFIB. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The number of artificial cardiac pacemakers is increasing, as is the number of bodies being cremated. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Importantly, asymptomatic first-degree family members of patients were found to have an intermediate phenotype for peripheral B- and T-cell subsets. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We tested 1,084 haplotype-tagging and functional variants from 164 genes in mitotic regulatory pathways in 791 Caucasian women with breast cancer and 843 healthy controls for association with risk of overall and high grade breast cancer. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These findings provide evidence for immunologically and temporally diverse body fat-dependent tradeoffs between immune function and growth during childhood. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In HLA-DQ2/8-positive patients, ZO-1 protein expression in the rectosigmoid mucosa was reduced compared with that in HLA-DQ2/8-negative patients and colonic transit was slower than in HLA-DQ2/8-negative patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Angiogenin levels were determined by radioimmunoassay and ELISA. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The study was conducted by using a self-administered questionnaire among 384 adolescents (65.4% boys; M = 16.05 years, SD = 1.39) studying at secondary schools of Birgunj. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Of the 12 SNPs reported in HBV-related HCC GWASs, five SNPs (rs7574865 in STAT4, rs9267673 near C2, rs2647073 and rs3997872 near HLA-DRB1 and rs9275319 near HLA-DQ), were found to be significantly associated with the risk of HBV-related LC (rs7574865: P\u2009=\u20091.79\u2009√ó\u200910(-2), OR\u2009=\u20091.17, 95% CI\u2009=\u20091.03-1.34; rs9267673: P\u2009=\u20094.91\u2009√ó\u200910(-4), OR\u2009=\u20091.37, 95% CI\u2009=\u20091.15-1.63; rs2647073: P\u2009=\u20093.53\u2009√ó\u200910(-5), OR\u2009=\u20091.63, 95% CI\u2009=\u20091.29-2.06; rs3997872: P\u2009=\u20094.22\u2009√ó\u200910(-4), OR\u2009=\u20091.86, 95% CI\u2009=\u20091.32-2.62; rs9275319: P\u2009=\u20091.30\u2009√ó\u200910(-2), OR\u2009=\u20091.32, 95% CI\u2009=\u20091.06-1.64). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As a result, 97 patients were chosen as subjects and divided into two groups: hepatectomy with (group A: n=50) and without (group B: n=47) pre-operative TAE. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Half consumed fewer serves of fruit and 88% consumed fewer serves of vegetables than national recommendations. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Predictors of the stable high-BMIz and rapid BMIz gain trajectories were pre-pregnancy BMI, gestational weight gain, Malay and Indian ethnicity, while predictors of stable low-BMIz trajectory were preterm delivery and Indian ethnicity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A cross-sectional survey was conducted between 2014 and 2015 as part of a nationwide survey using stratified four-stage random sampling in Xinjiang. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Younger students were more likely to have atopic dermatitis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | After each blood sample the CDI was in-vivo calibrated to the values simultaneously obtained from the ABL. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Following propensity score matching analysis, 2582 patients were included in each group. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In conclusion, colorectal cancer risk was related to an interactive effect between dietary lutein/zeaxanthin intake and the DICER1 rs3742330 polymorphism. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Methods: A total\nof 489 patients were included in the study. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We evaluated whether radiologically derived measures of body composition could explain more of the interpatient variability in aminoglycoside pharmacokinetics (PK) than standard body size metrics. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, ancillary analyses revealed a moderational effect of religious affiliation in the relationship between prayer and pain severity as well as pain tolerance. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Using a longitudinal cluster-randomized controlled design, we examined whether students' reading outcomes differed when they received 1, 2, or 3 years of individualized reading instruction from first through third grade, compared with a treated control group. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Demographic and surgical parameters were assessed, as well as the compliance with ERAS protocol elements, length of hospital stay, number of complications, and readmissions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | ACTH concentrations were lower in women than men (P < 0.01), and in women in the E2+ compared with E2- group under both continuous (P = 0.01) and pulsatile (P = 0.006) cortisol feedback, despite higher cortisol binding globulin and lower free cortisol levels in women than men (P < 0.01). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Chi-square analysis revealed no significant difference in the proportion of subjects (263/280 progesterone, 283/295 placebo) with Galveston Orientation and Amnesia Test scores ‚â•75. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additionally, eating competence was associated with a lower prevalence of previously undiagnosed type 2 diabetes, abdominal obesity, metabolic syndrome and hypertriglyceridaemia, and with better insulin sensitivity (p < 0.05 for all). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Data from 717 subjects undergoing HbsAg Ab and HBc Ab testing during the preventive medical examination, and receiving a booster dose of HBV vaccine when resulting with a non-protective titer (<10\xa0mIU/mL), were collected and analyzed. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Transplant centers and donor registries must both commit extra effort to incorporate new characteristics (beyond HLA, age, and parity) into improved donor selection. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In contrast, circulating follicular helper T-cell frequency and expression of inducible T-cell co-stimulator and chemokine receptors were only significantly altered in patients with common variable immunodeficiency. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, among the three SNPs associated with the risk of HCV-related HCC in previous GWASs, none of them showed significant association with the risk of HBV-related LC. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study suggests that HIV-infected individuals younger than 40 years and those with lower education level are more likely to have poorer QoL, while those receiving ARV treatment tend to have better QoL. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Survival analysis supported this result, with cutaneous lesions only manifesting in the advanced stages of infection, and therefore only being found on older voles. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our analysis suggests that the ST410 lineage should be classified with the potential to cause new high-risk clones. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Tranexamic acid did not have a statistically significant effect on blood loss. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | During each trial, the noise stimulus was applied for 3 of the 6min, and differences in stride, stance, and swing time variability were analyzed between noise and no-noise conditions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Short, daily exposure to a psychosocial/physical stressor, during the first week of life, resulted by adulthood in significant changes in neocortical thickness and architecture, which were further modulated by exposure to behavioral testing. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In conclusion, contrast-enhanced whole-heart CMRA at 3.0T can depict the normal and variant cardiac venous anatomy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In contrast, we found no statistically significant relationship between stress and atopic dermatitis in girls. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | After in-vivo calibration there was no statistical difference between the values of the CDI with and without calibration. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The postoperative pulmonary complications within the first 5 days were also observed.We chose 10\u200acm H2O and 8\u200acm H2O as the "ideal" PEEP for the C and the E groups, respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The complex interplay of psychosocial, structural, and physiological processes offers significant challenges to groups with entrenched health challenges. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The administration of oxandrolone was associated with improved lung function in pediatric burned patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Ninety-five cases of acute Q fever were identified. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | No bone metastases were found at the time of the initial diagnosis, and the patients were then re-assessed every 6 months for the first 5 years and then once a year. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The assessment of co-existing psychological and psychiatric disorders is advocated in the Standards of Care for the health of transsexual people. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Autologous stem cell transplantation (ASCT) is the gold standard therapy for suitable multiple myeloma (MM) patients after induction with high dose therapy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Pulmonary nodules (median 4, range 2-6), with or without cavitation were present in all patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Self-medication with analgesics in dental pain management is a common practice as most of these medicines are available over-the-counter (OTC). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Both GRS63 and GRS16 were associated with fractures. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition to the well-known melanoma susceptibility genes confirmed in the meta-analysis (MC1R, CDKN2A, TERT, OCA2 and ARNT/SETDB1), we also identified additional novel genes using FUMA to map SNPs to genes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Land-use mix was significantly associated with the use of public transit compared to private transport (adjusted odds ratio (aOR) =5.2, p = 0.002). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Future research should seek to implement additional evidence-based actions to improve QoL in this population. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | An outbreak of Q fever occurred in South Wales, United Kingdom, from July 15 through September 30, 2002. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Osteoarthritis is a degenerative joint disorder resulting in destruction of articular cartilage, osteophyte formation, and subchondral bone sclerosis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The top-scoring pair (TSP) algorithm classifies phenotypes according to the relative expression of a pair of genes. |