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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Unique identifiers: NCT01507831, NCT01623115, NCT01709500, NCT01617655, NCT01644175, NCT01644188, NCT01644474, NCT01730040, NCT01730053, and NCT01709513. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There was some evidence of a less steep socio-economic gradient in overweight in eight-year-old girls over time. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study confirms the well-known negative metabolic changes in PCOS patients. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Intraoperative radiographs may be valuable in setting of clinical suspicion. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although current consensus guidelines recommend consideration of CT in all TNBC larger than 5\xa0mm, clinicians should carefully discuss benefit/risk ratio with patients, given the unproven benefits. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | For a partial case-control study, log-linear model could estimate not only the main effect of environment but also gene-environment interaction. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We concluded that the effect of TAH or TAH+BSO operations were mainly on sexual desire and the number of weekly intercourse, and estrogen in the postoperative period did not make any difference between the two groups. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | High-risk populations may accept CESM as a screening exam and may prefer it over screening MRI if ongoing trials demonstrate screening CESM to be clinically non-inferior MRI. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study reveals a 4.6% annual increase in ED demand in WA in 2007-2013, mostly because of an increase in people with urgent and complex care needs, and not a shift (demand transfer) from primary care. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | palpation and Johnson's technique can be used as alternatives to ultrasound for EFW, particularly if the measurements are taken by experienced, skilled personnel. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | More than three-fourths of the patients in this study had a history of smoking, which is considered a triggering or aggravating factor for PPP. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is critically important to develop cost-effective strategies to reduce the TB burden. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | a high intake of fats, phosphorus, vitamin B5, vitamin E, and selenium intake and red meat appears to be related to the presence OSCC in Cordoba, Argentina. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These results should be confirmed in a larger trial and whether this advantage translates into an improvement in clinical outcome should be tested in a trial with primary clinical endpoints. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Success rates may be modest, but most adverse effects are mild and/or transient; however, significant loss of IOP control can occasionally occur. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | CLINICALTRIALS.GOV IDENTIFIER: NCT02244879. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our findings seem suggest that improving muscular fitness as well as an adherence to the SEADiet could be an important strategy to reduce clustered cardiometabolic risk in youth. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This suggests the need to compare acetate kinetics in normal and hyperinsulinaemic subjects. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Infusion sets containing di(2-ethylhexyl) phthalate should not be used with warming devices in order to avoid toxic effects. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, intensive prenatal nutrition counseling offered in an urban community health setting may decrease LGA births among a group of overweight and obese women from culturally diverse backgrounds at risk for adverse maternal and neonatal outcomes. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Surgeons should consider the predictors identified in our analysis to inform patients treated for tibial shaft fractures. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The participants had a high attendance rate in the program, which speaks to the likelihood of the applicability of the meditation program on an outpatient basis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | To confirm these findings, further prospective studies with larger sample size and longer follow-up are warranted. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Potentially pathogenic bacteria are detectable on ambulance staff uniforms when a shift ends. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A higher weight gain contributed in a negative manner to the presence of dyslipidemias in these patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Hypertension prevalence increased with age and was more prevalent among men than women. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Continuous monitoring of artemisinin effectiveness for malaria treatment should be established in high malaria transmission areas in sub-Saharan Africa where spread of resistance would be disastrous. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our findings suggest that tension and post-surgical factors play a causal role in this hitherto undescribed entity: post-reconstruction dermatitis of the breast. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Based on the findings of our study as well as other studies, we believe the minimally invasive percutaneous adhesiolysis procedure should be the first choice treatment option for patients with chronic lumbosacral radicular pain who present with clinical history and findings similar to those of the patients enrolled in our study. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The data were analyzed using IBM SPSS software version 22.0 (IBM Corporation, New York, USA); this cross-sectional study was conducted between April 2015 and May 2016.\xa0 |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We attempted to replicate these associations by similar analysis of two familial-obesity case-control cohorts and a population cohort, and detected GSVs at 11 out of 18 loci, at frequencies similar to those previously reported. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Follow-up data were obtained for 33 participants. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The stress level was found to be significantly associated with the risk of atopic dermatitis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Results - We found no statistically significant difference in the improvements in HOOS-PS between the treatment groups at 12-month follow-up. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | On Kaplan-Meier survival analysis, women with both an elevated level of CRP and a high NLR had a shorter admission-to-delivery interval compared to women with either an elevated level of CRP or a high NLR alone. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Further study is needed to verify this conclusion. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Negative sputum culture conversion was achieved and maintained in all except two mortalities. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These two gene pairs were validated in three independent data sets. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The physicochemical modification of allergen vaccines provides a chance for administering higher doses in a shorter period of time. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | E2 also suppressed ACTH ApEn (process randomness) during continuous cortisol feedback (P = 0.004). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This cross-sectional study was conducted among conveniently sampled patients attending dental clinics, located in Kuala Lumpur, Malaysia to assess association between self-medication with analgesics and patient's beliefs about medicines via Beliefs about Medicines Questionnaire. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The tolerance was assessed by recording all side effects related with immunotherapy. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Future studies are needed to determine if this intervention reduces falls risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | MATERIAL AND METHODS Medical records of 170 patients who underwent hysterectomy following cervical conization between November 2010 and September 2016 at the Zhenjiang 4th Hospital were reviewed. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Communal living participants who resided in the house for over 6 months showed the most substantial increases in tolerance. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Allergenic potency determined by enzyme allergosorbent test (EAST) inhibition and skin prick test showed that modified P. judaica pollen had a 99.9% less allergenicity than native extract. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The estimated NRS pain score on the day of surgery was 5.08 (95% confidence interval [CI] 4.97-5.19) in group N patients and 6.73 (95% CI 6.65-6.80) in group R patients (P\u200a<\u200a0.001). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We assessed the feasibility of hand-held photoscreeners to screen for vision disorders in pre-school children in Hawai'i. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therapies included opioids, nonsteroidal antiinflammatory drugs, acetaminophen-opioid combinations, postoperative continuous epidural infusion, anticonvulsants and tricyclic antidepressants for neuropathic pain, local anesthetic wound catheters, and continuous peripheral nerve block catheters. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Median time from onset of any symptoms to arrival at hospital was 22 hours longer for MPI poor adults compared to non-poor adults (123 vs. 101 hours) rising to a difference of 26 hours with adjustment in a multivariate regression model (95% confidence interval 7 to 46 hours; P = 0.009). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We found evidence of ST410 being a highly resistant globally distributed lineage, capable of patient-to-patient transmission causing hospital outbreaks. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The main outcome measures were mean ACTH concentrations, pulsatile ACTH secretion, and ACTH approximate entropy (ApEn). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | ROC curve of logARR and plasma renin activity in detection of primary aldosteronism with higher sensitivity and specificity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Reproductive factors have been linked to both breast cancer and DNA methylation, suggesting methylation as an important mechanism by which reproductive factors impact on disease risk. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These errors reflected the inability to define the word denoting the object more often than the inability to define the nature of the pictured object. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Carotid duplex ultrasound echobrightness, assessed in predefined tissue sites as a measure of arterial wall density, was significantly greater than age- and sex-matched controls in the intima-media (P<0.02), near adventitia (P<0.003), and deep adventitia (P<0.01), as was internal carotid artery mean flow velocity (P<0.0001). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Here, we investigated the function of local and systemic TNF in podocyte injury. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Future studies will link swallow imaging data of this kind with physiological and anatomical data in a manner not possible with human participants. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, there have been no controlled studies comparing patient-reported outcomes between them. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The subjects were previously randomized to either the control arm (n = 35) or the oxandrolone arm (0.1\u2009mg/kg twice/day for 12 months, n = 19). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this randomized controlled trial, we tested the hypothesis that patient-reported outcomes are better in patients who have undergone total hip arthroplasty (THA) with PA than in those who have undergone THA with LA, 12 months postoperatively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The genetically engineered V1442E-Na channel expressed in HEK cells shows marked enhancement of fast inactivation close to the resting potential, and enhanced use-dependent inactivation on high-frequency stimulation; S246L is likely a benign polymorphism. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Associations between environmental characteristics and likelihood of active commuting and public transit use were modeled using logistic regression with private transport (driving alone or carpool) as the reference category, adjusting for age, gender, and household car ownership. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Reducing DUP through better screening can decrease the psychosocial burden of disease and improve the trajectory of psychosis. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In patients at increased risk of CIN receiving prophylactic theophylline, hydration with sodium bicarbonate reduces contrast-induced renal impairment compared to hydration with saline. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Secondary outcomes were HOOS-Pain, HOOS-Quality-Of-Life, EQ-5D, UCLA Activity Score, and limping. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Before in-vivo calibration values from the CDI without gas calibration were significantly different from the ABL-values in accuracy as well as precision, whereas the results from the gas calibrated CDI were largely consistent with the ABL. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The time from search to transplant was identical for transplants using a KIR-genotyped versus a non-KIR-genotyped donor. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Four trajectories were identified: 73.2%(n\u2009=\u2009857) of the children showed a normal BMIz trajectory, 13.2%(n\u2009=\u2009155) a stable low-BMIz trajectory, 8.6%(n\u2009=\u2009100) a stable high-BMIz trajectory and 5.0%(n\u2009=\u200958) a rapid BMIz gain after 3 months trajectory. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Personality assessment can help a multidisciplinary gender dysphoria team detect potential psychopathological factors of vulnerability. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Moreover, they highlight the potential difficulty in replicating rare CNV associations across different populations. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Participants performed three 6-min walking trials while wearing a pair of insoles containing vibrating actuators. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Analyses of covariance did not reveal significant treatment effects for memory (Buschke immediate recall, p\u2009=\u20090.53; delayed recall, p\u2009=\u20090.94), attention (Trails A speed, p\u2009=\u20090.81 and errors, p\u2009=\u20090.22; Digit Span Forward length, p\u2009=\u20090.66), executive functioning (Trails B speed, p\u2009=\u20090.97 and errors, p\u2009=\u20090.93; Digit Span Backward length, p\u2009=\u20090.60), language (timed phonemic fluency, p\u2009=\u20090.05), and fine motor coordination/dexterity (Grooved Pegboard dominant hand time, p\u2009=\u20090.75 and peg drops, p\u2009=\u20090.59; nondominant hand time, p\u2009=\u20090.74 and peg drops, p\u2009=\u20090.61). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Deaths were attributed to central nervous system infection (11), malaria (3), urinary tract infection (2), gastrointestinal infection (1) and undifferentiated sepsis (1). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | DUP was estimated using Schedules of Clinical Assessment in Neuropsychiatry (SCAN). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Maximum expired ventilation (VEmax) was also measured in a subset of burned subjects. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Background. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Ongoing training was correlated with a reduction in DUP. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our results suggested that genetic variants associated with HBV-related hepatocarcinogenesis may already play an important role in the progression from CHB to LC. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The expression levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and high mobility group box 1 (HMGB1) in the cervical secretions and tissues were found to gradually increase, peaking at 2 weeks after conization, then significantly decreasing 3-6 weeks onwards. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Recent studies have reported multiple GSV loci associated with risk of obesity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Results show that there was a positive correlation between social anxiety symptoms and age, and girls reported more symptoms. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Participants beliefs in General-Harm (r = -0.243; p = 0.003) and General-Overuse (r = -0.203; p = 0.012) were negatively correlated with total QAQ point. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Median length of hospital stay was 5 days. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Prospective evaluation can rapidly identify KIR favorable genotype donors, but choosing more donors per search would substantially increase the likelihood of having a KIR best or better donor available for transplantation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The participants in\nthis study were women over 20 years old, who presented to Arnavutkoy State Hospital General surgery policlinic and\nSisli Hamidiye Etfal Family Medicine policlinic. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There was inconsistent evidence supporting a sustained first-grade treatment effect: Individualized instruction in first grade was necessary but not sufficient for stronger third-grade reading outcomes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The PaO2/FiO2 ratio in the E group was superior to that in the C group in the pneumoperitoneum period, though the difference was not significant (330\u200a±\u200a10 vs 305.56\u200a±\u200a4\u200amm Hg; P\u200a=\u200a0.09). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This study aimed to explore the associations of total stroke, including ischemic and hemorrhagic type, with sleep habits of a population in southern China. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Barriers to engaging in optimal energy balance focused more on motivation and attitude than on structural and material barriers. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Compared to leukocyte subset or CRP, NLR in women with funisitis was significantly higher than in women with HCA alone and showed higher predictive accuracy, along with 71.4% sensitivity, 77.9% specificity, 80.7% positive predictive value, and 67.8% negative predictive value for prediction of PIR. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Material and Methods. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We found that, regardless of treatment, bone metastases appeared in a certain number of patients and that after excluding patients with prostate cancer a bone metastasis was the first sign of "recurrence" in 1.3% of the patients with a known primary solid malignant tumour. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The AUC for plasma renin activity, logARR, and serum aldosterone are 0.855, 0.84, and 0.501, respectively. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In the combined groups, under both modes of cortisol addback, ACTH concentrations, pulsatile ACTH secretion, and ACTH secretory-burst mass correlated negatively and univariately with E2 levels (each P < 0.005). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The direct energetic nature of these relationships is indicated by (i) the manifestation of biomarker-specific negative immune effects only when examining growth over timeframes capturing active competition for energetic resources, (ii) the exaggerated impact of particularly costly inflammation on growth, and (iii) the ability of children with greater levels of body fat (i.e., energy reserves) to completely avoid the growth-inhibiting effects of acute inflammation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Ten patients had fracture before diagnosis of coeliac disease and six after diagnosis. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Thus, a protocol for clinicians to manage the patient presenting with oligometastatic prostate cancer would be a useful clinical tool. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Prediction of cancer progression after radical prostatectomy is one of the most challenging problems in the management of prostate cancer. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Bivariable and multivariable linear regression were used to assess relationships between PK parameters and covariates. |