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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The cost of extra sessions necessary to complete the FCU should be weighed against the potential benefit of reducing high-volume drinking when considering adding the FCU to an IMI for this population. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | ClinicalTrials.gov identifier: NCT00438698. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Symptoms develop earlier in patients with triple A syndrome, but the diagnosis is delayed and this has substantial nutritional impact. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The development of effective targeted therapies is essential for this breast cancer subtype. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Clinically, the implications of these findings will help to improve, specify, and increase the efficiency of the preoperative workup and counseling of patients with diabetes who need hip fracture surgery. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The prevalence of arterial hypertension in newly diagnosed type 2 diabetes is high. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Intraperitoneal chemotherapy can be used to prevent postoperative liver metastasis of gastric cancer. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Interventions to reduce indoor air pollution and to promote timely administration of measles vaccination are urgently needed to reduce the burden of severe pneumonia in children in Tanzania. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | DRD2 exhibits effects on weight gain from normal weight to overweight/obesity in adults, while, FTO is associated to weight gain from adolescence to young adulthood. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These results suggest that worry symptoms should be a focus of strategies to improve acute and maintenance treatment response in LLD. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Postprandial endothelial dysfunction is abnormal only in OH, and this effect does not appear to reflect increased inflammation. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Physicians' communication skills for frank and clear discussions about suicidality should be developed through various training courses. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These results should support allocative decisions of policymakers. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It adds to the literature suggesting that abdominoplasties in select patients may improve incontinence symptoms. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Quantitative assessment of patient requirements suggested that besides (tele)monitoring individualized care considering also noncardiac problems should be integrated in efforts to achieve more sustainable improvement in heart failure outcomes. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Measures oriented towards health behavior and psychosocial stress management should be encouraged among parents in order to decrease the risk of overweight/obesity in their children. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Among individuals with a history of SAMS, most will tolerate statin therapy. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Pre-operative body mass index was a useful predictor for recurrence and survival in patients who underwent microvascular reconstruction for head and neck squamous cell cancer. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Implications for Rehabilitation It is important to assess psychological factors such as poor pre-operative mental health and pain catastrophising in patients undergoing joint replacement surgery as these factors have an adverse effect on subjective patient outcomes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A negative result would be used to inform the research agenda and contribute to redefining future strategies for tackling obesity. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Findings provide additional support for the use of ERRT in treating nightmares and related difficulties and improving sleep. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The new point-of-care transcutaneous bilirubinometer, JM-103 Minolta, demonstrated good correlation with the serum bilirubin measurement in Chinese neonates aged 3 to 7 days. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, combining the data of both groups, significant improvements in HbA1c and BMI from baseline were observed. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The cell cycle progression test has a significant impact in assisting physicians and patients reach personalized treatment decisions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Combination of pertuzumab, trastuzumab and radiotherapy was well tolerated, which should be confirmed by the results of larger studies. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | cSEMSs for treatment of ABSs needed less endoscopic interventions to achieve similar efficacy as MPS and might become a new treatment standard. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Since this intervention was effective, it should be established in general practice as a means of improving patient knowledge about oral anticoagulation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Emergency and intensive care unit physicians were extremely reluctant to consider intensive care unit admission of patients aged > or =80 yrs, despite the presence of criteria indicating that intensive care unit admission was certainly or possibly appropriate. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | SLNB prior to NAT is an accurate method of axillary staging associated with a high identification rate. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Future study comparing results pre and post intervention is needed. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Ours is the first study to investigate genetic variability associated with inflammation, behaviorally related variables, and PCF for BCS. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The risk was similar to that in smokers, implying that smokers will not reduce their risk of type 2 diabetes by changing to snus use. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Ever consuming alcohol and ever smoking cigarette after starting ART, depression, not adhering to ART and being in the second lowest wealth quintile were significantly associated with malnutrition. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Bupivacaine could be a valid alternative to articaine especially due to its early postoperative pain prevention ability. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Thus, these substitutions could be useful to tackle the diabetes epidemic. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | MTA could be used as a safe medicament for pulpotomy in cariously exposed primary molars and could be a substitute for FC. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | (Funded by Pfizer; SPIRE-1 and SPIRE-2 ClinicalTrials.gov numbers, NCT01975376 and NCT01975389 .) |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Preconception supplementation with MM or IFA resulted in modest increases in maternal and infant iron stores but did not impact anemia. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Given that post-operative TSH levels were similar in the two groups, these observations are probably due to the correction of eSCH, suggesting a direct effect of eSCH on body weight regulation and lipid metabolism. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | While these SLIV programs are effective, to be as cost-effective as practice-based vaccination our SLIV programs would need to vaccinate more students and/or lower the costs for consent systems and project coordination. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These results suggest that adding social or affective components to physical activity may enhance engagement and retention in activity promotion efforts and their benefits on mental health. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This method provides an important technique that can be applied to other developing countries where a randomized study design is needed but infrastructure is lacking to implement more traditional participant selection methods. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Remaining at work also gives a better HRQoL. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | ANXA2 stromal expression might play a key role in aggressive tumor phenotype associated with increased EMT CTCs release, however, other factors beyond ANXA2 are responsible for coagulation activation mediated by CTCs in breast cancer patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, whilst the design was feasible, this trial has highlighted the lack of clinically and patient-relevant outcome measures that are appropriate for use in this setting for both research and clinical practice. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Prospective studies will clarify indications for RT in this patient population. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additionally, there is a need for improvement in the current health promotion programmes targeting breast cancer screening. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We believe that the atherogenic index also be used as a preliminary indication of accelerated atherosclerosis in FMF. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The CV risk factor reduction is related to the increased level of achieved free T(4) concentration. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Low newborn birth weight was related to the deteriorated nutritional status in terms of low anthropometric and abnormal biochemical measures. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The findings provide preliminary support for an indoor tanning intervention that engages tanners to challenge their beliefs about the benefits of indoor tanning. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Use of tolvaptan as an add-on therapy to loop diuretics can be considered an optimal therapeutic option in patients with insufficient response to loop diuretics. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Porous tantalum provided a reasonable alternative to bone graft in TTA. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Detrimental safety profile in pooled analysis supports current warnings. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The study suggests that individuals with high PBF make more impulsive food choices relative to those with low PBF, which could increase the risk of obesity over time. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Topical insulin is safe for human ocular usage. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Further, that these results would appear to corroborate the concept of increasing physical activity, including aerobic activity, as a preventative measure. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Eyes with better vision at baseline had a more favorable prognosis, whereas eyes with initial macular detachment, intraoperative iatrogenic break, or heavy SO showed more unfavorable outcomes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Elevated peak postoperative glucose levels were correlated with elevated HbA1c and were independently associated with major complications. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The use of a systematic intervention modeling process allows clearer understanding of the next appropriate steps which should involve further evaluation of the interventions using an interactive delivery method in a less selected group of study participants. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Rising plasma angiogenin levels in pregnancy may reflect persisting placental transformation and remodeling processes: in patients with highly pathologic Doppler flow findings these processes are disturbed and thus placental function is impaired. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Hair density and hair thickness of known nonbalding scalp regions showed some differences depending on the severity and the BASP subtypes in East Asian people with male pattern baldness. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These waters should be considered part of a healthy diet in order to prevent insulin resistance and cardiovascular disease. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Both placental BDNF gene expression and cord blood BDNF were downregulated in neonates with nondiabetic macrosomia compared with normal birth weight neonates. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although the incidence of BIS > 60 are very common in obese patients, true awareness during anaesthesia infrequent in this group of patients despite the type of anaesthesia, whether intravenous or inhalation. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This finding suggests that both GSTM1-null and GSTT1-null may contribute to the clinical course of T2DM patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | There is some research evidence that suggests that men and women approach potential drunk drivers differently. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In addition to being above the level of measurement uncertainty, a 20% change in retinal thickness in patients with macular edema seems to be optimal for clinically important changes in visual acuity and may be considered as an outcome for clinical trials of treatments for uveitic macular edema. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This study provides preliminary evidence that web-based computer-tailored interventions can be used to increase physical activity among breast cancer survivors. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Visual outcomes, PCO development over time and need for Nd:YAG laser treatment were similar for the two IOLs. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This intervention was successful in improving weight, engagement in strength exercises, increasing levels of moderate-intensity physical activity and consumption of fruit among retirement village residents. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The renal and cardiac TOD evolution, as well as the PAIx and CAIx, did not change in either group. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is concluded that oral NaAcetate could be used as both an alkalinizing agent and an alternative energy source in the horse. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | According to the microbiological culture results, a specific bacterium responsible for halitosis in children could not be identified and more sensitive methods might be used for this purpose. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These results provide initial support for PNC as a model for brief treatment with non-treatment seeking adolescents who are heavy users of cannabis. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | RELEVANCE TO CLINICAL PRACTICE: In clinical practice, breast-related stereotype threat should be measured together with prevalent symptoms (e.g. anxiety, depression and fatigue) in patients with breast cancer. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This study reveals the importance of considering proximity as an important dimension of exercise outcomes-particularly when promoting intrinsic motivation among relatively infrequent exercisers. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Either topical tretinoin (0.25%) or retinol (0.25%) can be used safely and effectively when applied in office immediately after SA peeling to ameliorate signs of photoaging. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In extremely premature newborns, incorrect UVC placement is significantly associated with death through its relation to severe periventricular hemorrhage. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Apple pectin may potentially be an alternative to aspirin for the prevention of NIF. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Both general and central adiposity have causal effects on CHD and type 2 diabetes mellitus. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Universities or colleges could serve as a research platform to evaluate such intervention strategies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, this volume reduction impacts cognition and clinical manifestation of the illnesses differentially. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Diabetics and controls exhibited increased adiponectin levels due to falciparum malaria but differed in response in terms of leptin levels. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Disease etiology, baseline factors (NYHA FC, PVRI and SVO(2)) and on-treatment factors (6MWD, SVO(2) and treprostinil dose) were predictors of survival in this study and may be used to aid in treatment optimization. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although further research from controlled studies is needed and despite the presence of other possible confounding factors, monitoring for neuropathy and vitamin B12 and folate levels merits consideration in patients on long-term treatment with new AEDs. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Salt water rinse can be used as adjunct to routine mechanical plaque control for prevention of oral diseases. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Sweet solution can be used as a simple and safe method to reduce the distress following immunization in infants up to 12 months. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | For Medicare beneficiaries with nonmetastatic breast cancer, residence in regions with higher breast cancer-related expenditures was not associated with better survival. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The reduction in median and peak concentrations of 1-hpur, which reflects total exposure to, and internal dose of PAHs, was most evident in workers employed in the units where preventive measures had been taken. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | CinnoVex can be used as a safe and effective alternative to Avonex in treatment of RRMS. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Public Health Implications. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The measurement of serum lactate level was a better marker of oxidative stress among patients with OSAS. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, with this cross-sectional study it is not possible to conclude if these factors play a role individually or collectively or are a serendipitous association, for which large scale analytical studies are required. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The introduction of ART can enhance dyslipidemia, increasing cardiovascular risk, especially among those who have classic risks of cardiovascular disease. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This may elevate the risk of atherosclerosis, particularly cardiovascular disorders. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Future clinical trials should explore the potential of high doses of nabiximols for cannabis dependence. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Pregnancies in youth with type 2 diabetes may be especially prone to result in congenital anomalies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Physiological and psychological impact of this type of event is still unclear. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The obesogenic effect of p,p-DDE is a major determinant responsible for the association of p,p-DDE with LV mass. |