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In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The aim of this study was to determine whether myocardial contrast echocardiography performed with a stable solution of sonicated albumin could detect regions of myocardial underperfusion resulting from various degrees of coronary stenosis .
### Output Text: | The aim of this study was to determine whether myocardial contrast echocardiography performed with a stable solution of sonicated albumin could detect regions of myocardial underperfusion resulting from various degrees of coronary stenosis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The perfusion defect produced in 16 open chest dogs was compared with the anatomic area at risk measured by the postmortem dual - perfusion technique and with thallium - 201 single - photon emission tomography ( SPECT ) .
### Output Text: | The perfusion defect produced in 16 open chest dogs was compared with the anatomic area at risk measured by the postmortem dual - perfusion technique and with <span class="chemical">thallium</span> - 201 single - photon emission tomography ( SPECT ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: During a transient ( 20 - s ) coronary occlusion , a perfusion defect was observed with contrast echocardiography in 14 of the 15 dogs in which the occlusion was produced .
### Output Text: | During a transient ( 20 - s ) coronary occlusion , a perfusion defect was observed with contrast echocardiography in 14 of the 15 dogs in which the occlusion was produced . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The perfusion defect correlated significantly with the anatomic area at risk ( r = 0 . 74 ; p less than 0 . 002 ) .
### Output Text: | The perfusion defect correlated significantly with the anatomic area at risk ( r = 0 . 74 ; p less than 0 . 002 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: During dipyridamole - induced hyperemia , 12 of the 16 dogs with a partial coronary stenosis had a visible area of hypoperfusion by contrast echocardiography .
### Output Text: | During <span class="chemical">dipyridamole</span> - induced hyperemia , 12 of the 16 dogs with a partial coronary stenosis had a visible area of hypoperfusion by contrast echocardiography . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The four dogs without a perfusion defect had a stenosis that resulted in a mild ( 0 % to 50 % ) reduction in dipyridamole - induced hyperemia .
### Output Text: | The four dogs without a perfusion defect had a stenosis that resulted in a mild ( 0 % to 50 % ) reduction in <span class="chemical">dipyridamole</span> - induced hyperemia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The size of the perfusion defect during stenosis correlated significantly with the anatomic area at risk ( r = 0 . 61 ; p = 0 . 02 ) .
### Output Text: | The size of the perfusion defect during stenosis correlated significantly with the anatomic area at risk ( r = 0 . 61 ; p = 0 . 02 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Thallium - 201 SPECT demonstrated a perfusion defect in all 14 dogs analyzed during dipyridamole - induced hyperemia ; the size of the perfusion defect correlated with the anatomic area at risk ( r = 0 . 58 ; p less than 0 . 03 ) and with the perfusion defect by contrast echocardiography ( r = 0 . 58 ; p less than 0 . 03 ) .
### Output Text: | <span class="chemical">Thallium</span> - 201 SPECT demonstrated a perfusion defect in all 14 dogs analyzed during <span class="chemical">dipyridamole</span> - induced hyperemia ; the size of the perfusion defect correlated with the anatomic area at risk ( r = 0 . 58 ; p less than 0 . 03 ) and with the perfusion defect by contrast echocardiography ( r = 0 . 58 ; p less than 0 . 03 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Thus , myocardial contrast echocardiography can be used to visualize and quantitate the amount of jeopardized myocardium during moderate to severe degrees of coronary stenosis .
### Output Text: | Thus , myocardial contrast echocardiography can be used to visualize and quantitate the amount of jeopardized myocardium during moderate to severe degrees of coronary stenosis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: The results obtained show a correlation with the anatomic area at risk similar to that obtained with thallium - 201 SPECT .
### Output Text: | The results obtained show a correlation with the anatomic area at risk similar to that obtained with <span class="chemical">thallium</span> - 201 SPECT . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: The activation of spinal N - methyl - D - aspartate receptors may contribute to degeneration of spinal motor neurons induced by neuraxial morphine after a noninjurious interval of spinal cord ischemia .
### Output Text: | The activation of spinal <span class="chemical">N - methyl - D - aspartate</span> receptors may contribute to degeneration of spinal motor neurons induced by neuraxial <span class="chemical">morphine</span> after a noninjurious interval of spinal cord ischemia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: We investigated the relationship between the degeneration of spinal motor neurons and activation of N - methyl - d - aspartate ( NMDA ) receptors after neuraxial morphine following a noninjurious interval of aortic occlusion in rats .
### Output Text: | We investigated the relationship between the degeneration of spinal motor neurons and activation of <span class="chemical">N - methyl - d - aspartate</span> ( <span class="chemical">NMDA</span> ) receptors after neuraxial <span class="chemical">morphine</span> following a noninjurious interval of aortic occlusion in rats . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Spinal cord ischemia was induced by aortic occlusion for 6 min with a balloon catheter .
### Output Text: | Spinal cord ischemia was induced by aortic occlusion for 6 min with a balloon catheter . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: In a microdialysis study , 10 muL of saline ( group C ; n = 8 ) or 30 mug of morphine ( group M ; n = 8 ) was injected intrathecally ( IT ) 0 . 5 h after reflow , and 30 mug of morphine ( group SM ; n = 8 ) or 10 muL of saline ( group SC ; n = 8 ) was injected IT 0 . 5 h after sham operation .
### Output Text: | In a microdialysis study , 10 muL of saline ( group C ; n = 8 ) or 30 mug of <span class="chemical">morphine</span> ( group M ; n = 8 ) was injected intrathecally ( IT ) 0 . 5 h after reflow , and 30 mug of <span class="chemical">morphine</span> ( group SM ; n = 8 ) or 10 muL of saline ( group SC ; n = 8 ) was injected IT 0 . 5 h after sham operation . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Microdialysis samples were collected preischemia , before IT injection , and at 2 , 4 , 8 , 24 , and 48 h of reperfusion ( after IT injection ) .
### Output Text: | Microdialysis samples were collected preischemia , before IT injection , and at 2 , 4 , 8 , 24 , and 48 h of reperfusion ( after IT injection ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Second , we investigated the effect of IT MK - 801 ( 30 mug ) on the histopathologic changes in the spinal cord after morphine - induced spastic paraparesis .
### Output Text: | Second , we investigated the effect of IT <span class="chemical">MK - 801</span> ( 30 mug ) on the histopathologic changes in the spinal cord after <span class="chemical">morphine</span> - induced spastic paraparesis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: After IT morphine , the cerebrospinal fluid ( CSF ) glutamate concentration was increased in group M relative to both baseline and group C ( P < 0 . 05 ) .
### Output Text: | After IT <span class="chemical">morphine</span> , the cerebrospinal fluid ( CSF ) <span class="chemical">glutamate</span> concentration was increased in group M relative to both baseline and group C ( P < 0 . 05 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: This increase persisted for 8 hrs .
### Output Text: | This increase persisted for 8 hrs . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: IT MK - 801 significantly reduced the number of dark - stained alpha - motoneurons after morphine - induced spastic paraparesis compared with the saline group .
### Output Text: | IT <span class="chemical">MK - 801</span> significantly reduced the number of dark - stained alpha - motoneurons after <span class="chemical">morphine</span> - induced spastic paraparesis compared with the saline group . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: These data indicate that IT morphine induces spastic paraparesis with a concomitant increase in CSF glutamate , which is involved in NMDA receptor activation .
### Output Text: | These data indicate that IT <span class="chemical">morphine</span> induces spastic paraparesis with a concomitant increase in CSF <span class="chemical">glutamate</span> , which is involved in <span class="chemical">NMDA</span> receptor activation . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: We suggest that opioids may be neurotoxic in the setting of spinal cord ischemia via NMDA receptor activation .
### Output Text: | We suggest that opioids may be neurotoxic in the setting of spinal cord ischemia via <span class="chemical">NMDA</span> receptor activation . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Acute low back pain during intravenous administration of amiodarone : a report of two cases .
### Output Text: | Acute low back pain during intravenous administration of <span class="chemical">amiodarone</span> : a report of two cases . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Amiodarone represents an effective antiarrhythmic drug for cardioversion of recent - onset atrial fibrillation ( AF ) and maintenance of sinus rhythm .
### Output Text: | <span class="chemical">Amiodarone</span> represents an effective antiarrhythmic drug for cardioversion of recent - onset atrial fibrillation ( AF ) and maintenance of sinus rhythm . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: We briefly describe two patients suffering from recent - onset atrial fibrillation , who experienced an acute devastating low back pain a few minutes after initiation of intravenous amiodarone loading .
### Output Text: | We briefly describe two patients suffering from recent - onset atrial fibrillation , who experienced an acute devastating low back pain a few minutes after initiation of intravenous <span class="chemical">amiodarone</span> loading . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Notably , this side effect has not been ever reported in the medical literature .
### Output Text: | Notably , this side effect has not been ever reported in the medical literature . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Clinicians should be aware of this reaction since prompt termination of parenteral administration leads to complete resolution .
### Output Text: | Clinicians should be aware of this reaction since prompt termination of parenteral administration leads to complete resolution . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Quantitative drug levels in stimulant psychosis : relationship to symptom severity , catecholamines and hyperkinesia .
### Output Text: | Quantitative drug levels in stimulant psychosis : relationship to symptom severity , <span class="chemical">catecholamines</span> and hyperkinesia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: To examine the relationship between quantitative stimulant drug levels , catecholamines , and psychotic symptoms , nineteen patients in a psychiatric emergency service with a diagnosis of amphetamine - or cocaine - induced psychosis were interviewed , and plasma and urine were collected for quantitative assays of stimulant drug and catecholamine metabolite levels .
### Output Text: | To examine the relationship between quantitative stimulant drug levels , <span class="chemical">catecholamines</span> , and psychotic symptoms , nineteen patients in a psychiatric emergency service with a diagnosis of <span class="chemical">amphetamine</span> - or <span class="chemical">cocaine</span> - induced psychosis were interviewed , and plasma and urine were collected for quantitative assays of stimulant drug and <span class="chemical">catecholamine</span> metabolite levels . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Methamphetamine or amphetamine levels were related to several psychopathology scores and the global hyperkinesia rating .
### Output Text: | <span class="chemical">Methamphetamine</span> or <span class="chemical">amphetamine</span> levels were related to several psychopathology scores and the global hyperkinesia rating . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: HVA levels were related to global hyperkinesia but not to psychopathology ratings .
### Output Text: | HVA levels were related to global hyperkinesia but not to psychopathology ratings . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Although many other factors such as sensitization may play a role , intensity of stimulant - induced psychotic symptoms and stereotypies appears to be at least in part dose - related .
### Output Text: | Although many other factors such as sensitization may play a role , intensity of stimulant - induced psychotic symptoms and stereotypies appears to be at least in part dose - related . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Pheochromocytoma unmasked by amisulpride and tiapride .
### Output Text: | Pheochromocytoma unmasked by <span class="chemical">amisulpride</span> and <span class="chemical">tiapride</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: OBJECTIVE : To describe the unmasking of pheochromocytoma in a patient treated with amisulpride and tiapride .
### Output Text: | OBJECTIVE : To describe the unmasking of pheochromocytoma in a patient treated with <span class="chemical">amisulpride</span> and <span class="chemical">tiapride</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: CASE SUMMARY : A 42 - year - old white man developed acute hypertension with severe headache and vomiting 2 hours after the first doses of amisulpride 100 mg and tiapride 100 mg .
### Output Text: | CASE SUMMARY : A 42 - year - old white man developed acute hypertension with severe headache and vomiting 2 hours after the first doses of <span class="chemical">amisulpride</span> 100 mg and <span class="chemical">tiapride</span> 100 mg . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Both drugs were immediately discontinued , and the patient recovered after subsequent nicardipine and verapamil treatment .
### Output Text: | Both drugs were immediately discontinued , and the patient recovered after subsequent <span class="chemical">nicardipine</span> and <span class="chemical">verapamil</span> treatment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Abdominal ultrasound showed an adrenal mass , and postoperative histologic examination confirmed the diagnosis of pheochromocytoma .
### Output Text: | Abdominal ultrasound showed an adrenal mass , and postoperative histologic examination confirmed the diagnosis of pheochromocytoma . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: DISCUSSION : Drug - induced symptoms of pheochromocytoma are often associated with the use of substituted benzamide drugs , but the underlying mechanism is unknown .
### Output Text: | DISCUSSION : Drug - induced symptoms of pheochromocytoma are often associated with the use of substituted <span class="chemical">benzamide</span> drugs , but the underlying mechanism is unknown . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: In our case , use of the Naranjo probability scale indicated a possible relationship between the hypertensive crisis and amisulpride and tiapride therapy .
### Output Text: | In our case , use of the Naranjo probability scale indicated a possible relationship between the hypertensive crisis and <span class="chemical">amisulpride</span> and <span class="chemical">tiapride</span> therapy . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSIONS : As of March 24 , 2005 , this is the first reported case of amisulpride - and tiapride - induced hypertensive crisis in a patient with pheochromocytoma .
### Output Text: | CONCLUSIONS : As of March 24 , 2005 , this is the first reported case of <span class="chemical">amisulpride</span> - and <span class="chemical">tiapride</span> - induced hypertensive crisis in a patient with pheochromocytoma . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Physicians and other healthcare professionals should be aware of this potential adverse effect of tiapride and amisulpride .
### Output Text: | Physicians and other healthcare professionals should be aware of this potential adverse effect of <span class="chemical">tiapride</span> and <span class="chemical">amisulpride</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Minor neurological dysfunction , cognitive development , and somatic development at the age of 3 to 7 years after dexamethasone treatment in very - low birth - weight infants .
### Output Text: | Minor neurological dysfunction , cognitive development , and somatic development at the age of 3 to 7 years after <span class="chemical">dexamethasone</span> treatment in very - low birth - weight infants . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: The objective of this study was to assess minor neurological dysfunction , cognitive development , and somatic development after dexamethasone therapy in very - low - birthweight infants .
### Output Text: | The objective of this study was to assess minor neurological dysfunction , cognitive development , and somatic development after <span class="chemical">dexamethasone</span> therapy in very - low - birthweight infants . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Thirty - three children after dexamethasone treatment were matched to 33 children without dexamethasone treatment .
### Output Text: | Thirty - three children after <span class="chemical">dexamethasone</span> treatment were matched to 33 children without <span class="chemical">dexamethasone</span> treatment . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Data were assessed at the age of 3 - 7 years .
### Output Text: | Data were assessed at the age of 3 - 7 years . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Dexamethasone was started between the 7th and the 28th day of life over 7 days with a total dose of 2 . 35 mg / kg / day .
### Output Text: | <span class="chemical">Dexamethasone</span> was started between the 7th and the 28th day of life over 7 days with a total dose of 2 . 35 mg / kg / day . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Exclusion criteria were asphyxia , malformations , major surgical interventions , small for gestational age , intraventricular haemorrhage grades III and IV , periventricular leukomalacia , and severe psychomotor retardation .
### Output Text: | Exclusion criteria were asphyxia , malformations , major surgical interventions , small for gestational age , intraventricular haemorrhage grades III and IV , periventricular leukomalacia , and severe psychomotor retardation . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Each child was examined by a neuropediatrician for minor neurological dysfunctions and tested by a psychologist for cognitive development with a Kaufman Assessment Battery for Children and a Draw - a - Man Test .
### Output Text: | Each child was examined by a neuropediatrician for minor neurological dysfunctions and tested by a psychologist for cognitive development with a Kaufman Assessment Battery for Children and a Draw - a - Man Test . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: There were no differences in demographic data , growth , and socio - economic status between the two groups .
### Output Text: | There were no differences in demographic data , growth , and socio - economic status between the two groups . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Fine motor skills and gross motor function were significantly better in the control group ( p < 0 . 01 ) .
### Output Text: | Fine motor skills and gross motor function were significantly better in the control group ( p < 0 . 01 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: In the Draw - a - Man Test , the control group showed better results ( p < 0 . 001 ) .
### Output Text: | In the Draw - a - Man Test , the control group showed better results ( p < 0 . 001 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: There were no differences in development of speech , social development , and the Kaufman Assessment Battery for Children .
### Output Text: | There were no differences in development of speech , social development , and the Kaufman Assessment Battery for Children . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: After dexamethasone treatment , children showed a higher rate of minor neurological dysfunctions .
### Output Text: | After <span class="chemical">dexamethasone</span> treatment , children showed a higher rate of minor neurological dysfunctions . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Neurological development was affected even without neurological diagnosis .
### Output Text: | Neurological development was affected even without neurological diagnosis . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Further long - term follow - up studies will be necessary to fully evaluate the impact of dexamethasone on neurological and cognitive development .
### Output Text: | Further long - term follow - up studies will be necessary to fully evaluate the impact of <span class="chemical">dexamethasone</span> on neurological and cognitive development . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Valproic acid I : time course of lipid peroxidation biomarkers , liver toxicity , and valproic acid metabolite levels in rats .
### Output Text: | <span class="chemical">Valproic acid</span> I : time course of lipid peroxidation biomarkers , liver toxicity , and <span class="chemical">valproic acid</span> metabolite levels in rats . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: A single dose of valproic acid ( VPA ) , which is a widely used antiepileptic drug , is associated with oxidative stress in rats , as recently demonstrated by elevated levels of 15 - F ( 2t ) - isoprostane ( 15 - F ( 2t ) - IsoP ) .
### Output Text: | A single dose of <span class="chemical">valproic acid</span> ( <span class="chemical">VPA</span> ) , which is a widely used antiepileptic drug , is associated with oxidative stress in rats , as recently demonstrated by elevated levels of <span class="chemical">15 - F ( 2t ) - isoprostane</span> ( <span class="chemical">15 - F ( 2t ) - IsoP</span> ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: To determine whether there was a temporal relationship between VPA - associated oxidative stress and hepatotoxicity , adult male Sprague - Dawley rats were treated ip with VPA ( 500 mg / kg ) or 0 . 9 % saline ( vehicle ) once daily for 2 , 4 , 7 , 10 , or 14 days .
### Output Text: | To determine whether there was a temporal relationship between <span class="chemical">VPA</span> - associated oxidative stress and hepatotoxicity , adult male Sprague - Dawley rats were treated ip with <span class="chemical">VPA</span> ( 500 mg / kg ) or 0 . 9 % saline ( vehicle ) once daily for 2 , 4 , 7 , 10 , or 14 days . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Oxidative stress was assessed by determining plasma and liver levels of 15 - F ( 2t ) - IsoP , lipid hydroperoxides ( LPO ) , and thiobarbituric acid reactive substances ( TBARs ) .
### Output Text: | Oxidative stress was assessed by determining plasma and liver levels of <span class="chemical">15 - F ( 2t ) - IsoP</span> , <span class="chemical">lipid hydroperoxides</span> ( <span class="chemical">LPO</span> ) , and <span class="chemical">thiobarbituric acid reactive substances</span> ( <span class="chemical">TBARs</span> ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Plasma and liver 15 - F ( 2t ) - IsoP were elevated and reached a plateau after day 2 of VPA treatment compared to control .
### Output Text: | Plasma and liver <span class="chemical">15 - F ( 2t ) - IsoP</span> were elevated and reached a plateau after day 2 of <span class="chemical">VPA</span> treatment compared to control . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Liver LPO levels were not elevated until day 7 of treatment ( 1 . 8 - fold versus control , p < 0 . 05 ) .
### Output Text: | Liver <span class="chemical">LPO</span> levels were not elevated until day 7 of treatment ( 1 . 8 - fold versus control , p < 0 . 05 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Liver and plasma TBARs were not increased until 14 days ( 2 - fold vs . control , p < 0 . 05 ) .
### Output Text: | Liver and plasma <span class="chemical">TBARs</span> were not increased until 14 days ( 2 - fold vs . control , p < 0 . 05 ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Liver toxicity was evaluated based on serum levels of alpha - glutathione S - transferase ( alpha - GST ) and by histology .
### Output Text: | Liver toxicity was evaluated based on serum levels of alpha - <span class="chemical">glutathione</span> S - transferase ( alpha - GST ) and by histology . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Serum alpha - GST levels were significantly elevated by day 4 , which corresponded to hepatotoxicity as shown by the increasing incidence of inflammation of the liver capsule , necrosis , and steatosis throughout the study .
### Output Text: | Serum alpha - GST levels were significantly elevated by day 4 , which corresponded to hepatotoxicity as shown by the increasing incidence of inflammation of the liver capsule , necrosis , and steatosis throughout the study . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: The liver levels of beta - oxidation metabolites of VPA were decreased by day 14 , while the levels of 4 - ene - VPA and ( E ) - 2 , 4 - diene - VPA were not elevated throughout the study .
### Output Text: | The liver levels of beta - oxidation metabolites of <span class="chemical">VPA</span> were decreased by day 14 , while the levels of <span class="chemical">4 - ene - VPA</span> and ( E ) - <span class="chemical">2 , 4 - diene - VPA</span> were not elevated throughout the study . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Overall , these findings indicate that VPA treatment results in oxidative stress , as measured by levels of 15 - F ( 2t ) - IsoP , which precedes the onset of necrosis , steatosis , and elevated levels of serum alpha - GST .
### Output Text: | Overall , these findings indicate that <span class="chemical">VPA</span> treatment results in oxidative stress , as measured by levels of <span class="chemical">15 - F ( 2t ) - IsoP</span> , which precedes the onset of necrosis , steatosis , and elevated levels of serum alpha - GST . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Assessment of perinatal hepatitis B and rubella prevention in New Hampshire delivery hospitals .
### Output Text: | Assessment of perinatal hepatitis B and rubella prevention in New Hampshire delivery hospitals . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: OBJECTIVE : To evaluate current performance on recommended perinatal hepatitis B and rubella prevention practices in New Hampshire .
### Output Text: | OBJECTIVE : To evaluate current performance on recommended perinatal hepatitis B and rubella prevention practices in New Hampshire . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: METHODS : Data were extracted from 2021 paired mother - infant records for the year 2000 birth cohort in New Hampshire ' s 25 delivery hospitals .
### Output Text: | METHODS : Data were extracted from 2021 paired mother - infant records for the year 2000 birth cohort in New Hampshire ' s 25 delivery hospitals . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Assessment was done on the following : prenatal screening for hepatitis B and rubella , administration of the hepatitis B vaccine birth dose to all infants , administration of hepatitis B immune globulin to infants who were born to hepatitis B surface antigen - positive mothers , rubella immunity , and administration of in - hospital postpartum rubella vaccine to rubella nonimmune women .
### Output Text: | Assessment was done on the following : prenatal screening for hepatitis B and rubella , administration of the hepatitis B vaccine birth dose to all infants , administration of hepatitis B immune globulin to infants who were born to <span class="chemical">hepatitis B surface antigen</span> - positive mothers , rubella immunity , and administration of in - hospital postpartum rubella vaccine to rubella nonimmune women . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: RESULTS : Prenatal screening rates for hepatitis B ( 98 . 8 % ) and rubella ( 99 . 4 % ) were high .
### Output Text: | RESULTS : Prenatal screening rates for hepatitis B ( 98 . 8 % ) and rubella ( 99 . 4 % ) were high . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Hepatitis B vaccine birth dose was administered to 76 . 2 % of all infants .
### Output Text: | Hepatitis B vaccine birth dose was administered to 76 . 2 % of all infants . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: All infants who were born to hepatitis B surface antigen - positive mothers also received hepatitis B immune globulin .
### Output Text: | All infants who were born to <span class="chemical">hepatitis B surface antigen</span> - positive mothers also received hepatitis B immune globulin . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Multivariate logistic regression showed that the month of delivery and infant birth weight were independent predictors of hepatitis B vaccination .
### Output Text: | Multivariate logistic regression showed that the month of delivery and infant birth weight were independent predictors of hepatitis B vaccination . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: The proportion of infants who were vaccinated in January and February 2000 ( 48 . 5 % and 67 . 5 % , respectively ) was less than any other months , whereas the proportion who were vaccinated in December 2000 ( 88 . 2 % ) was the highest .
### Output Text: | The proportion of infants who were vaccinated in January and February 2000 ( 48 . 5 % and 67 . 5 % , respectively ) was less than any other months , whereas the proportion who were vaccinated in December 2000 ( 88 . 2 % ) was the highest . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Women who were born between 1971 and 1975 had the highest rate of rubella nonimmunity ( 9 . 5 % ) .
### Output Text: | Women who were born between 1971 and 1975 had the highest rate of rubella nonimmunity ( 9 . 5 % ) . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: In - hospital postpartum rubella vaccine administration was documented for 75 . 6 % of nonimmune women .
### Output Text: | In - hospital postpartum rubella vaccine administration was documented for 75 . 6 % of nonimmune women . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSION : This study documents good compliance in New Hampshire ' s birthing hospitals with national guidelines for perinatal hepatitis B and rubella prevention and highlights potential areas for improvement .
### Output Text: | CONCLUSION : This study documents good compliance in New Hampshire ' s birthing hospitals with national guidelines for perinatal hepatitis B and rubella prevention and highlights potential areas for improvement . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Succinylcholine - induced masseter muscle rigidity during bronchoscopic removal of a tracheal foreign body .
### Output Text: | <span class="chemical">Succinylcholine</span> - induced masseter muscle rigidity during bronchoscopic removal of a tracheal foreign body . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Masseter muscle rigidity during general anesthesia is considered an early warning sign of a possible episode of malignant hyperthermia .
### Output Text: | Masseter muscle rigidity during general anesthesia is considered an early warning sign of a possible episode of malignant hyperthermia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: The decision whether to continue or discontinue the procedure depends on the urgency of the surgery and severity of masseter muscle rigidity .
### Output Text: | The decision whether to continue or discontinue the procedure depends on the urgency of the surgery and severity of masseter muscle rigidity . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Here , we describe a case of severe masseter muscle rigidity ( jaw of steel ) after succinylcholine ( Sch ) administration during general anesthetic management for rigid bronchoscopic removal of a tracheal foreign body .
### Output Text: | Here , we describe a case of severe masseter muscle rigidity ( jaw of steel ) after <span class="chemical">succinylcholine</span> ( <span class="chemical">Sch</span> ) administration during general anesthetic management for rigid bronchoscopic removal of a tracheal foreign body . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Anesthesia was continued uneventfully with propofol infusion while all facilities were available to detect and treat malignant hyperthermia .
### Output Text: | Anesthesia was continued uneventfully with <span class="chemical">propofol</span> infusion while all facilities were available to detect and treat malignant hyperthermia . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: Dexrazoxane protects against myelosuppression from the DNA cleavage - enhancing drugs etoposide and daunorubicin but not doxorubicin .
### Output Text: | <span class="chemical">Dexrazoxane</span> protects against myelosuppression from the DNA cleavage - enhancing drugs <span class="chemical">etoposide</span> and <span class="chemical">daunorubicin</span> but not <span class="chemical">doxorubicin</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: PURPOSE : The anthracyclines daunorubicin and doxorubicin and the epipodophyllotoxin etoposide are potent DNA cleavage - enhancing drugs that are widely used in clinical oncology ; however , myelosuppression and cardiac toxicity limit their use .
### Output Text: | PURPOSE : The <span class="chemical">anthracyclines</span> <span class="chemical">daunorubicin</span> and <span class="chemical">doxorubicin</span> and the <span class="chemical">epipodophyllotoxin</span> <span class="chemical">etoposide</span> are potent DNA cleavage - enhancing drugs that are widely used in clinical oncology ; however , myelosuppression and cardiac toxicity limit their use . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Dexrazoxane ( ICRF - 187 ) is recommended for protection against anthracycline - induced cardiotoxicity .
### Output Text: | <span class="chemical">Dexrazoxane</span> ( <span class="chemical">ICRF - 187</span> ) is recommended for protection against <span class="chemical">anthracycline</span> - induced cardiotoxicity . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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### Input Text: EXPERIMENTAL DESIGN : Because of their widespread use , the hematologic toxicity following coadministration of dexrazoxane and these three structurally different DNA cleavage enhancers was investigated : Sensitivity of human and murine blood progenitor cells to etoposide , daunorubicin , and doxorubicin + / - dexrazoxane was determined in granulocyte - macrophage colony forming assays .
### Output Text: | EXPERIMENTAL DESIGN : Because of their widespread use , the hematologic toxicity following coadministration of <span class="chemical">dexrazoxane</span> and these three structurally different DNA cleavage enhancers was investigated : Sensitivity of human and murine blood progenitor cells to <span class="chemical">etoposide</span> , <span class="chemical">daunorubicin</span> , and <span class="chemical">doxorubicin</span> + / - <span class="chemical">dexrazoxane</span> was determined in granulocyte - macrophage colony forming assays . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Likewise , in vivo , B6D2F1 mice were treated with etoposide , daunorubicin , and doxorubicin , with or without dexrazoxane over a wide range of doses : posttreatment , a full hematologic evaluation was done .
### Output Text: | Likewise , in vivo , B6D2F1 mice were treated with <span class="chemical">etoposide</span> , <span class="chemical">daunorubicin</span> , and <span class="chemical">doxorubicin</span> , with or without <span class="chemical">dexrazoxane</span> over a wide range of doses : posttreatment , a full hematologic evaluation was done . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: RESULTS : Nontoxic doses of dexrazoxane reduced myelosuppression and weight loss from daunorubicin and etoposide in mice and antagonized their antiproliferative effects in the colony assay ; however , dexrazoxane neither reduced myelosuppression , weight loss , nor the in vitro cytotoxicity from doxorubicin .
### Output Text: | RESULTS : Nontoxic doses of <span class="chemical">dexrazoxane</span> reduced myelosuppression and weight loss from <span class="chemical">daunorubicin</span> and <span class="chemical">etoposide</span> in mice and antagonized their antiproliferative effects in the colony assay ; however , <span class="chemical">dexrazoxane</span> neither reduced myelosuppression , weight loss , nor the in vitro cytotoxicity from <span class="chemical">doxorubicin</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: CONCLUSION : Although our findings support the observation that dexrazoxane reduces neither hematologic activity nor antitumor activity from doxorubicin clinically , the potent antagonism of daunorubicin activity raises concern ; a possible interference with anticancer efficacy certainly would call for renewed attention .
### Output Text: | CONCLUSION : Although our findings support the observation that <span class="chemical">dexrazoxane</span> reduces neither hematologic activity nor antitumor activity from <span class="chemical">doxorubicin</span> clinically , the potent antagonism of <span class="chemical">daunorubicin</span> activity raises concern ; a possible interference with anticancer efficacy certainly would call for renewed attention . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Our data also suggest that significant etoposide dose escalation is perhaps possible by the use of dexrazoxane .
### Output Text: | Our data also suggest that significant <span class="chemical">etoposide</span> dose escalation is perhaps possible by the use of <span class="chemical">dexrazoxane</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: Clinical trials in patients with brain metastases combining dexrazoxane and high doses of etoposide is ongoing with the aim of improving efficacy without aggravating hematologic toxicity .
### Output Text: | Clinical trials in patients with brain metastases combining <span class="chemical">dexrazoxane</span> and high doses of <span class="chemical">etoposide</span> is ongoing with the aim of improving efficacy without aggravating hematologic toxicity . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: If successful , this represents an exciting mechanism for pharmacologic regulation of side effects from cytotoxic chemotherapy .
### Output Text: | If successful , this represents an exciting mechanism for pharmacologic regulation of side effects from cytotoxic chemotherapy . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: Assessment of the onset and persistence of amnesia during procedural sedation with propofol .
### Output Text: | Assessment of the onset and persistence of amnesia during procedural sedation with <span class="chemical">propofol</span> . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: OBJECTIVES : To assess patients ' ability to repeat and recall words presented to them while undergoing procedural sedation with propofol , and correlate their recall with their level of awareness as measured by bispectral index ( BIS ) monitoring .
### Output Text: | OBJECTIVES : To assess patients ' ability to repeat and recall words presented to them while undergoing procedural sedation with <span class="chemical">propofol</span> , and correlate their recall with their level of awareness as measured by bispectral index ( BIS ) monitoring . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
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Use <span class="chemical"> to denote a chemical.
### Input Text: METHODS : This was a prospective , single - intervention study of consenting adult patients undergoing procedural sedation with propofol between December 28 , 2002 , and October 31 , 2003 .
### Output Text: | METHODS : This was a prospective , single - intervention study of consenting adult patients undergoing procedural sedation with <span class="chemical">propofol</span> between December 28 , 2002 , and October 31 , 2003 . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: BIS monitoring was initiated starting 3 minutes before the procedure and continuing until the patient had regained baseline mental status .
### Output Text: | BIS monitoring was initiated starting 3 minutes before the procedure and continuing until the patient had regained baseline mental status . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: At 1 - minute intervals during the procedural sedation , until the patient regained baseline mental status at the end of the procedure , a word from a standardized list was read aloud , and the patient was asked to immediately repeat the word to the investigator .
### Output Text: | At 1 - minute intervals during the procedural sedation , until the patient regained baseline mental status at the end of the procedure , a word from a standardized list was read aloud , and the patient was asked to immediately repeat the word to the investigator . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: The BIS score at the time the word was read and the patient ' s ability to repeat the word were recorded .
### Output Text: | The BIS score at the time the word was read and the patient ' s ability to repeat the word were recorded . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: After the procedure , the patient was asked to state all of the words from the list that he or she could recall , and to identify the last word recalled from prior to the start of the procedure and the first word recalled from after the procedure was completed .
### Output Text: | After the procedure , the patient was asked to state all of the words from the list that he or she could recall , and to identify the last word recalled from prior to the start of the procedure and the first word recalled from after the procedure was completed . |
In the sentence extracted from biomedical literature, identify all the chemical entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities.
### Entity Markup Guides:
Use <span class="chemical"> to denote a chemical.
### Input Text: RESULTS : Seventy - five consenting patients were enrolled ; one patient was excluded from data analysis for a protocol violation .
### Output Text: | RESULTS : Seventy - five consenting patients were enrolled ; one patient was excluded from data analysis for a protocol violation . |
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