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This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | States of frailty were highly present in the hospital environment. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | (Funded by Novo Nordisk and the National Institutes of Health; LEADER ClinicalTrials.gov number, NCT01179048 .) |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This helps to optimize patient care and lowers postoperative morbidity. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our data suggests that age and obesity may contribute to the sex-specific incidence of EGFR mutation in lung adenocarcinoma in different manners. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Only one of the three methods allowed for the detection of changes from the normal capillary density as early as at the severe nonproliferative DR stage due to several refinements from the basic technique. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | CBT and PE can have salutary effects on endocrine symptoms and, to a lesser degree, on sexuality and physical functioning of patients with breast cancer experiencing treatment-induced menopause. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These data provide insight into the mechanisms by which rexinoids cause central hypothyroidism and potential ways this effect can be used for treatment of disorders such as thyroid hormone resistance and TSH-secreting pituitary tumors. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Children with S-ECC appear to have relatively poor nutritional health compared to caries-free controls, and were significantly more likely to have low vitamin D, calcium, and albumin concentrations and elevated PTH levels. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Thus, same-statin rechallenge might warrant increased utilization. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Approximately one half of patients with coronary disease do not achieve their target lipid levels as defined in the European guidelines, and this rate is less than reported in previous studies. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In delayed responders, this may have implications for switching or not switching therapies. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Surgical management is required for some complications, but most can be managed medically. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | SNP -420C-C homozygozity status seems to be associated with more deleterious metabolic profile. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The GSTM1 genotype does not relate with remission and partial remission rates after 1 course treatment of AL patients, but relates with LDH level. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Based on data from this large population of irradiated RC, number of nodes assessed has no prognostic impact in node-negative patients. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Also, given the impressive results obtained with ranibizumab for all types of neovascular AMD, neither PDT nor low-dose TTT should be considered as first-line treatments. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The results support the use of regular physical activity as a method for managing state anxiety in young adults. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our study provides preliminary evidence that mothers who consume diets higher in fruit and lower in fried foods and cured meats during pregnancy may reduce the risk of unilateral retinoblastoma in their offspring. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The insulin adjustments are much larger than common recommendations. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Previous breast cancer treatment with chemotherapy, radiotherapy\xa0or both should be considered when assessing a patients cardiovascular risk profile. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It was also observed that mean age at diagnosis is a decade earlier than in western countries. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | s The Ethiopian health care reform has laid the groundwork for health system improvement, but progress was slow and the health care delivery system was still fragile. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | With the exception of reduced bone health, older adults with undiagnosed CD had limited comorbidity and no increase in mortality compared with controls. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The high prevalence of PPV administration in children with SCD diagnosed by newborn screening had a significant impact on the incidence of IPD with improved patient outcomes. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This model needs to be tested in future prospective research. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, there is a risk of thrombo-embolic and pulmonary stenosis complications which needs to be addressed and prospectively monitored. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In a placebo-controlled, randomized trial, we found a prebiotic (OI) to selectively alter the intestinal microbiota and significantly reduce body weight z-score, percent body fat, percent trunk fat, and serum level of interleukin 6 in children with overweight or obesity (Clinicaltrials.gov no:\xa0NCT02125955). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Both of these potential sources were removed, and subsequent active surveillance did not reveal any further cases of M. wolinskyi SSI. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Interventions to promote earlier HIV diagnosis and treatment and integrating nutrition counseling at all stages of ART implementation may improve ART outcomes in this vulnerable population. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This form of immunotherapy may be an attractive option for some patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Serum TTR did not show a significant difference by nutrition support in massively burned patients with >20% of TBSA burned. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This may have implications for the significance of these abnormalities regarding prospects in IVF/ICSI treatment cycles. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Despite access to Xpert, the majority of children with presumptive TB were treated based on clinical diagnosis. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The results support the use of the BITSEA as a tool for child health professionals in the early detection of psychosocial problems in 2-year-olds. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In our trial, inhibition of PCSK9 with evolocumab on a background of statin therapy lowered LDL cholesterol levels to a median of 30 mg per deciliter (0.78 mmol per liter) and reduced the risk of cardiovascular events. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | More prospective data are needed to confirm these associations. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It can be used as an economical and effective rescue plan. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Our findings also emphasize the importance of the prevention of severe obesity to prevent future-related problems such as hypertension in children and adolescents. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Elevation of perioperative NT-proBNP is a strong independent predictor of postoperative AF in patients undergoing thoracic surgery for lung cancer. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The use of second generation tyrosine kinase inhibitors led to obtain a complete cytogenetic and major molecular response in fewer time. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It could be a good alternative to oral liquid nutritional supplements to counteract protein-energy-malnutrition. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This subset of patients will be the cohort for a prospective study to assess whether collar immobilization is necessary. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This finding has major implications for use of nursing staff and cost of NH care. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, continuing effort and attention are essential as the effect does not persist when intervention ends. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, LE of the primary tumor is recommended when technically feasible. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Registered 15 March 2014. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additional studies on omega-3 and omega-6 intake in relation to inflammatory biomarkers in patients in secondary prevention of CVD are needed, particularly regarding dietary patterns that are rich in some sources of PUFA. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Non-HDL cholesterol is most strongly associated with premature coronary artery disease and could serve as preferred risk predictor and therapeutic target in this young patient population (≤ 40 years). |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | A relationship between hypercoagulability detected by whole blood thromboelastometry and aggregometry and increased fat mass is shown. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | At the doses given, the two amino acids did not affect subjective appetite feelings. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Patients treated with clindamycin and those with a peripherally inserted central catheter had higher rates of unplanned outpatient visits. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This provides a molecular mechanism linking oxidative stress and downregulation of channel expression observed in cardiovascular diseases. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This notion may have an impact on self-perception and dieting behaviour in certain individuals, precipitating and promoting disturbed eating attitudes and behaviour that may lead to the onset of eating disorders. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Based on the results of this study, as well as the opinions of other authors, it can be concluded that the eversion carotid endarterectomy has an advantage over the conventional procedure.We recommend conventional procedure only in cases when retrograde pressure indicates the use of the intraluminal shunting. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Functioning seems to be a mediating factor between positive symptoms and S-QoL. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Preoperative G8 scores can help forecast postoperative complications in older HCC patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The difference in 30-day outcome was not influenced by the use of different therapeutic modalities, including thrombolysis and invasive coronary procedures, but was rather due to the older age and greater comorbidity of women; these findings seem also to explain the less frequent use of invasive procedures in women. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The high level of hazardous drinking among people with facial trauma suggests a clear need for alcohol screening and intervention. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Aml/Val+HCTZ triple therapy may be a suitable option for patients requiring more than two agents to reach target BP. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The association of resistin with PA was stronger than the association of HDL cholesterol with PA, making resistin a potentially useful biomarker of PA. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We should have major policy changes to increase future screening programs and health education programs which would have an overall positive impact on reducing the disease burden. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | As such, care should be taken to avoid minor LLD, as it could inadvertently develop on using offloading devices. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Primary surgery with or without radiotherapy may provide a value treatment option for young LSCC. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These data can be used to inform intervention activities. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | In this pilot study, applying TNP to acute high-risk foot wounds in patients with diabetes or end-stage renal failure improved the wound healing rate in reference to wound depth. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | PAV+ may be used as a useful mode of support in critically ill patients. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This study shows that boiled crude palm oil may have a mild, triacylglycerol-reducing effect in young, healthy individuals and may also show a mild LDL-C-increasing effect in males. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Maxillary three-implant overdentures are a viable treatment option for edentulous patients wearing opposing mandibular two-implant overdentures. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We confirmed the robust association of MTNR1B rs10830963/G variant with GDM binary and glycemic traits in this Caucasian case-control study. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Considering the fact that the quality of life improved significantly after operation, elective repair of symptomatic inguinal hernias should be undertaken as promptly as possible. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | TRIAL REGISTRATION: This study used an observational prospective design. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Moreover, infants and toddlers, who comprise the main target group in YF endemic regions, and populations with high HIV infection rates, respond to YFV with lower antibody levels. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Additional study to determine outcomes beyond 2 years with a bone-anchored annular closure device is warranted. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The consumption of unhydrolyzed milk proteins (56 g/d) for 8 wk improved vascular reactivity, biomarkers of endothelial function, and lipid risk factors. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The likelihood of malignancy for a NML on screening breast US was greater than 2%. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | (Funded by Amylin Pharmaceuticals; EXSCEL ClinicalTrials.gov number, NCT01144338 .) |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Future studies should determine whether in obese subjects with CTS the weight and waist circumference loss produces an improvement in CTS symptoms and recovery of distal conduction velocity of the median nerve. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Each 1 mg dL(-1) increase in HDL decreased the odds of severe sepsis by 3% during hospitalization. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Yoga therapy may be used to alleviate anxiety symptoms in cancer patients and should be the subject of further research. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Both total extra-oral time and time stored dry are important factors for the onset of resorption in replanted avulsed teeth in children. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Strength training increases strength in partially paralysed muscles of people with recent SCI, although it is not clear whether the size of the treatment effect is clinically meaningful. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Intervention with a fiber-rich diet with brown rice effectively improved endothelial function, without changes in HbA1c levels, possibly through reducing glucose excursions. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Strategies need to be developed to improve OA care, including educating general practitioners in evidence-based treatment recommendations and in the assessment of hand pain, and encourage the routine referral of patients with symptomatic hand OA to occupational therapy before considering surgery. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | It is quite common but not detectable with fasting laboratory values-the screening recommended by current guidelines. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Therefore, revaprazan can be used as an effective drug for acid-related disease. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Reusables may provide a useful alternative to disposable products in certain circumstances. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | We conclude that appearance should be considered an important motivator for surgery and determinant of satisfaction. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The authors postulate that this percentage could be even higher if protocols were initiated to biopsy these small lesions with larger core biopsies and possibly alleviate the need for formal surgery in these specific, small lesion. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Although further investigation of long-term and prospective studies is needed, we identified four variables as predisposing factors for higher major amputation in diabetic patients through meta-analysis. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | However, although exploratory and in need of replication, it introduces the possibility that epistasis between the OPRM1 gene and DAT gene might need to be taken into account when examining differential genetic response to alcohol or medication treatment, especially in early-stage alcoholics. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Interventions to reduce inequalities should consider the influence of education, income, and occupation in diet to be most effective. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Considering the relatively small sample size of the current study, caution should be taken when adopting the conclusions. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | This technique was statistically associated with a reduction in the severity of acute-on-chronic lithium poisoning at a given ingested dose and serum lithium level. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Reviewed studies were heterogeneous and lacked the methodologic rigor to draw any conclusions regarding the effects of dietary cholesterol on CVD risk. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Iron reduction may be a safe and low-cost alternative to statins. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Worse QOL was correlated with poorer values for FEF 25-75%. |
This is no advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | APBI in Japanese women provides satisfactory clinical results except for cosmetic outcomes. |
This is a weak advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | The findings provide provisional support for the acceptability of the MYLO program in a non-clinical sample although its efficacy as an innovative computer-based aid to problem solving remains unclear. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | Parents should be counselled about the risks of pregnancy loss with or without VAS insertion. |
This is a strong advice | Question: is this a 2) strong advice, 1) weak advice 0) no advice? | These must be started before inserting the LT or a different supraglottic airway adjunct and be delivered continuously during insertion. |