jablonkagroup/chempile-lift · Datasets at Hugging Face

The compound with the SMILES of Fc1ccc(cc1OC(F)(F)F)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of FC(F)(F)c1cc(ccc1)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ccc(cc1C#N)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O=C(NCC1CCCCC1)C(Cc1cc2cc(ccc2nc1N)-c1ccccc1C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of O1c2c(cc(cc2)CC)C([NH2+]CC(O)C2NC(=O)C=3C=C(N4CCCC4)C(=O)N(CCCCc4cc(C2)ccc4)C=3)CC12CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCCC)C1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(Oc2ccccc2)C1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(Oc2ncccc2)C1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCc2cc(ccc2)C(F)(F)F)C1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C2NC(=O)C=3C=CC(=O)N(CCCc4cc(C2)ccc4)C=3)CC12CCC2)CC(C)(C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ccc(cc1CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2)C#C displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(c1)/C(=N\O)/C)C(=O)N(CCC)CCC)C(O)C[NH2+]Cc1cc(OC)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S(=O)(=O)(N(c1cc(cc(OCC)c1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)c1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCc2cc(ccc2)C#N)C1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)NC(C(O)CC(C(=O)NC(C(C)C)C(=O)NCc1ccccc1)C)COc1cc(F)cc(F)c1)C(=O)NC(C)c1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)C(O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)COC)Cc2cc(ccc2)C#C)CC12CCC2)CC(C)(C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1ccccc1CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(ccc1OC)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)NC(C(O)CC(C(=O)NC(C(C)C)C(=O)NCc1ccccc1)C)COCc1ccccc1)C(=O)NC(C)c1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ccc(cc1C#C)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ccc(cc1C)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(c1)C(=O)N(CCC)CCC)C(=O)C)C(O)C[NH2+]Cc1cc(OC)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S(=O)(=O)(N(c1cc(cc(c1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)C1CCCC1)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]Cc2c(C1)cccc2OC displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ccc(cc1OC)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(C(O)CCC)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCCC)C1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S1(=O)(=O)N(c2cc(cc3n(cc(CC1)c23)CC)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C1CCOCC1)C displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3n(cc(CC1)c23)CC)C(=O)NC([C@H](O)CNc1ccccc1)Cc1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C(CCCC(C)C)(C)C)C displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)N[C@H]([C@H](O)C[NH2+]C1CCOCC1)Cc1ccccc1)CC displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S(=O)(=O)(N(c1cc(cc(c1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)C(C)C)c1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)C)Cc2ccccc2)CC12CCC2)CC(C)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(C(O)CCC)C1=O)CCc1ccccc1)C(O)C[NH2+]Cc1cc(OC)ccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of s1cncc1-c1cc(ccc1)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)COC)Cc2cc3OCOc3cc2)CC12CCC2)CC(C)(C)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(CC(C)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCCC)C1 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of s1cc(nc1-c1cc(ccc1)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)COCC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)C)Cc2ccccc2)CC12CCC2)CC(C)(C)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(Oc2cccnc2)C1 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of O1c2c(cc(cc2)CC)C([NH2+]CC(O)C2NC(=O)C=3C=C(c4ncccc4)C(=O)N(CCCCc4cc(C2)ccc4)C=3)CC12CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S(=O)(=O)(N(c1cc(cc(c1)/C(=N\OCCC)/C)C(=O)NC([C@@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1cc(F)cc(F)c1)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S1(=O)(=O)N(CCCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+]C(C)(C)c1cc(ccc1)C(F)(F)F)Cc1ccccc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc3c(COC3(C)C)cc2)C1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C[NH2+]Cc1cc(OC)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of s1ccnc1-c1cc(ccc1F)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)C1OCCC1)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1c2c(ccc1)C(N=C2N)(c1cc(ccc1)-c1cc(cnc1)C#CC)c1cc(ncc1)C(F)F exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(F)ccc1CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of s1cc(nc1)-c1cc(ccc1)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]CCC(F)(F)F)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C1CCCCC1)CC displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)NC(C)c1ccc(F)cc1)-c1oc(cn1)C([NH3+])(Cc1ccccc1)C)C displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2noc(c2)CC(C)(C)C)C1 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)[C@@H](OC)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1c2c(n(c1)C(=O)N(CCCC)C)cccc2)C(O)C[NH2+]Cc1cc(OC)ccc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S1(Oc2cc(cc3c2n(cc3CC)CC1)C(=O)NC([C@H](O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)Cc1ccccc1)(=O)=O shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S(=O)(=O)(N(c1cc(ccc1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C(C(=O)NC1CCCCC1)C)c1cc(ccc1)C#N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)C)Cc2cc3OCOc3cc2)CC12CCC2)CC(C)(C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of O=C1N(C)C(=NC1(c1cc(ccc1)-c1cncnc1)c1cn(nc1)CCCC)N displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Clc1ccc(cc1)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1c2cccnc2n(c1)C(=O)N(CCCC)C)C(O)C[NH2+]Cc1cc(ccc1)CC exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CC\C(=N\O)\CC1)c1cc(ccc1)C(C)(C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S(=O)(=O)(N(c1cc(cc(c1)/C(=N\O)/C)C(=O)N[C@H]([C@@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1cc(F)cc(F)c1)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3n(cc(CC1)c23)CC)C(=O)NC([C@H](O)C[NH2+]C1CC1)Cc1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C1CCCCC1)C displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1CCCCOc2nc(cc(c2)C(=O)NC(Cc2cc1ccc2)C(O)C[NH2+]C1(CC1)c1cc(ccc1)C(C)C)COC shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)[C@H]1OCCC1)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)COC)Cc2cc(ccc2)-c2ncccc2)CC12CCC2)CC(C)(C)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of s1ccnc1-c1cc(CC(NC(=O)COC)C(O)C[NH2+]C2CC3(Oc4ncc(cc24)CC(C)(C)C)CCC3)c(F)cc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)COC)Cc2cc(ccc2)-c2occn2)CC12CCC2)CC(C)(C)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of s1ccnc1-c1cc(ccc1)CC(NC(=O)C(OC)OC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(c1)/C(=N\OCC=C)/C)C(=O)N(CCC)CCC)C(O)C[NH2+]Cc1cc(OC)ccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(c1)C(=O)N(CCC)CCC)CCO)C(O)C[NH2+]Cc1cc(OC)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S(=O)(=O)(N(c1cc(cc(c1)/C(=N/OC)/C)C(=O)NC([C@@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1cc(F)cc(F)c1)c1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(Oc2ccccc2)c1)C(=O)N(CCC)CCC)C(O)C[NH2+]Cc1cc(OC)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(Oc2ccc(OC)cc2)c1)C(=O)N(CCC)CCC)C(O)C[NH2+]Cc1cc(OC)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1ccc(cc1-c1cccnc1F)[C@@]1(N=C(N)N(C)C1=O)c1cc(C)c(OC)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)NC(C(O)C[C@@H](C(=O)NC(C(C)C)C(=O)NCc1ccccc1)C)COc1cc(F)cc(F)c1)C(=O)NC(C)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ncccc1-c1cc(ccc1)C1(N=C(N)N(C)C1=O)c1cc(nc(c1)CC)CC displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Clc1ccc(N(S(=O)(=O)C)c2cc(ccc2)C(=O)NC(Cc2ccccc2)C(O)C[NH2+]C(C(=O)NC2CCCCC2)C)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1ncccc1-c1cc(ccc1)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 displays inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of FCC#Cc1cc(ccc1)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of FCCC#Cc1cc(ccc1)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)C#CCCO exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)C#CCCCCO exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ccc(cc1OCCCF)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of FC(F)CCOc1cc(ccc1)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1c2cccnc2n(c1)C(=O)N1CCC[C@@H]1COC)[C@H](O)C[NH2+]Cc1cc(OC)ccc1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCc2ccc(F)cc2)C1 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ncccc1-c1cc(ccc1)C1(N=C(N)N(C)C1=O)c1cn(nc1)CC shows inhibition of the human beta-secretase 1 (BACE-1).

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The compound with the SMILES of Fc1ncccc1-c1cc(ccc1)C1(N=C(N)N(C)C1=O)c1cn(nc1)CCCC displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of s1cc(cc1C(=O)CC)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1F displays inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of O1c2c(cc(cc2)-c2cc(cnc2)C#CC)C2(N=C(N)N(C)C2=O)CC1(C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of Fc1ccc(cc1C(F)(F)F)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).

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The chemical with the SMILES of S(=O)(=O)(N(c1cc(ccc1)C(=O)N[C@H]([C@@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1cc(F)cc(F)c1)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).

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