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jablonkagroup
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chempile-lift

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The compound with the SMILES of O1CC[C@@H](NC(=O)[C@@H](Cc2cc3cc(ccc3nc2N)-c2ccccc2C)C)CC1(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O1CC[C@@H](NC(=O)[C@@H](Cc2cc3cc(ccc3nc2N)-c2ccccc2C)C)CC1(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)[C@@H](N1CC[C@](NC(=O)C)(CC(C)C)C1=O)CCc1ccccc1)[C@H](O)[C@@H]1[NH2+]C[C@H](OCCC)C1 shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)[C@@H](N1CC[C@](NC(=O)C)(CC(C)C)C1=O)CCc1ccccc1)[C@H](O)[C@@H]1[NH2+]C[C@H](OCCC)C1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)Cc1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)Cc1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S(=O)(=O)(CCCCC)C[C@@H](NC(=O)c1cccnc1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)CC)Cc1cc(F)cc(F)c1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S(=O)(=O)(CCCCC)C[C@@H](NC(=O)c1cccnc1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)CC)Cc1cc(F)cc(F)c1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O1c2c(cc(cc2)CC)[C@@H]([NH2+]C[C@@H](O)[C@H]2NC(=O)C=3C=CC(=O)N(CCCCc4cc(C2)ccc4)C=3)CC12CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O1c2c(cc(cc2)CC)[C@@H]([NH2+]C[C@@H](O)[C@H]2NC(=O)C=3C=CC(=O)N(CCCCc4cc(C2)ccc4)C=3)CC12CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]C[C@H](Oc2ccccc2)C1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]C[C@H](Oc2ccccc2)C1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]CCN(Cc2ccccc2)C1=O displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]CCN(Cc2ccccc2)C1=O displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1(=O)(=O)N(CCCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)Cc1ccccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1(=O)(=O)N(CCCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)C(F)(F)F)Cc1ccccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(=O)(=O)(N(c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+][C@H](C(=O)NC1CCCCC1)C)Cc1ccccc1)c1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(=O)(=O)(N(c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+][C@H](C(=O)NC1CCCCC1)C)Cc1ccccc1)c1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)C[NH2+]Cc1cc(OC)ccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)C[NH2+]Cc1cc(OC)ccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]C[C@H](OCc2ccccc2)C1 displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]C[C@H](OCc2ccccc2)C1 displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Ic1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)Cc1cc(F)cc(F)c1 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Ic1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)Cc1cc(F)cc(F)c1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]CN(Cc2ccccc2)C1=O shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]CN(Cc2ccccc2)C1=O shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(=O)(=O)(N1C[C@@H]([NH2+]CC1)[C@@H](O)[C@@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)Cc1cc(F)cc(F)c1)c1ccccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(=O)(=O)(N1C[C@@H]([NH2+]CC1)[C@@H](O)[C@@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)Cc1cc(F)cc(F)c1)c1ccccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1ccc(cc1)C[C@H](NC(=O)C)[C@H](O)C[NH2+][C@H]1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(cc1)C[C@H](NC(=O)C)[C@H](O)C[NH2+][C@H]1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)[C@@H](N1CC[C@](NC(=O)C)([C@H](CC)C)C1=O)CCc1ccccc1)Cc1ccccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)[C@@H](N1CC[C@](NC(=O)C)([C@H](CC)C)C1=O)CCc1ccccc1)Cc1ccccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of s1ccnc1-c1cc(ccc1)C[C@H](NC(=O)[C@H](OC)C)[C@H](O)C[NH2+][C@H]1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of s1ccnc1-c1cc(ccc1)C[C@H](NC(=O)[C@H](OC)C)[C@H](O)C[NH2+][C@H]1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)C[C@H](C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1)C)COCc1cc(F)cc(F)c1)C(=O)N[C@H](C)c1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)C[C@H](C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1)C)COCc1cc(F)cc(F)c1)C(=O)N[C@H](C)c1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)C[NH2+][C@H](C(=O)NCC(C)C)C)C(=O)N[C@H](C)c1ccc(F)cc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)C[NH2+][C@H](C(=O)NCC(C)C)C)C(=O)N[C@H](C)c1ccc(F)cc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Clc1cc2CC([NH+]=C(N[C@@H](C[C@H]3[C@H](SC=C3c3cn[nH]c3)CCC)C(=O)[O-])c2cc1)(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Clc1cc2CC([NH+]=C(N[C@@H](C[C@H]3[C@H](SC=C3c3cn[nH]c3)CCC)C(=O)[O-])c2cc1)(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O1C[C@]2(N=C1N)c1cc(ccc1Oc1c2cc(OCC(C)C)cc1)-c1cncnc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O1C[C@]2(N=C1N)c1cc(ccc1Oc1c2cc(OCC(C)C)cc1)-c1cncnc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)[C@@H](N1CC[C@](NC(=O)C)(CC(C)C)C1=O)CCc1ccccc1)[C@H](O)[C@@H]1[NH2+]Cc2c(C1)cccc2 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)[C@@H](N1CC[C@](NC(=O)C)(CC(C)C)C1=O)CCc1ccccc1)[C@H](O)[C@@H]1[NH2+]Cc2c(C1)cccc2 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of s1c2OC(C[C@H]([NH2+]C[C@@H](O)[C@@H](NC(=O)C)Cc3ccccc3)c2cc1CC(C)(C)C)(C)C shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of s1c2OC(C[C@H]([NH2+]C[C@@H](O)[C@@H](NC(=O)C)Cc3ccccc3)c2cc1CC(C)(C)C)(C)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S(CC[C@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)C(=O)N[C@H]([C@@H](O)[C@@H]1CC(=O)C[C@H]1C(=O)N[C@@H](C(C)C)C(=O)[NH2+]CCCC)CC(C)C)C displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S(CC[C@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)C(=O)N[C@H]([C@@H](O)[C@@H]1CC(=O)C[C@H]1C(=O)N[C@@H](C(C)C)C(=O)[NH2+]CCCC)CC(C)C)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of s1cc(cc1)C[C@H](NC(=O)c1cc(nc(NC[C@H]2C[C@@H]2C)c1)N(S(=O)(=O)C)C)[C@@H]([NH3+])CCCC exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of s1cc(cc1)C[C@H](NC(=O)c1cc(nc(NC[C@H]2C[C@@H]2C)c1)N(S(=O)(=O)C)C)[C@@H]([NH3+])CCCC exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C(=O)N)C(=O)N(CCC)CCC)[C@H](O)C[NH2+]Cc1cc(OC)ccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C(=O)N)C(=O)N(CCC)CCC)[C@H](O)C[NH2+]Cc1cc(OC)ccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O=C(NCC1CCCCC1)[C@@H](Cc1cc2cc(ccc2nc1N)-c1ccccc1C)CCC displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O=C(NCC1CCCCC1)[C@@H](Cc1cc2cc(ccc2nc1N)-c1ccccc1C)CCC displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H](C)c1ccc(F)cc1)-c1oc(nn1)[C@]([NH3+])(Cc1ccccc1)C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H](C)c1ccc(F)cc1)-c1oc(nn1)[C@]([NH3+])(Cc1ccccc1)C)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@@H](C1)C(F)(F)F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@@H](C1)C(F)(F)F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O=C1N(CCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+][C@H](C(=O)NC1CCCCC1)C)Cc1ccccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O=C1N(CCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+][C@H](C(=O)NC1CCCCC1)C)Cc1ccccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@H](C(F)(F)F)[C@@H]1F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@H](C(F)(F)F)[C@@H]1F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(cc1C#CCCCF)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(cc1C#CCCCF)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@H](O)C[NH2+]C1CC1)Cc1ccccc1)C(=O)N[C@H](C)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@H](O)C[NH2+]C1CC1)Cc1ccccc1)C(=O)N[C@H](C)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S(=O)(=O)(N(c1cc(ccc1)C(=O)N[C@H]([C@H](O)C[NH2+][C@H](C(=O)NC1CCCCC1)C)Cc1ccccc1)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S(=O)(=O)(N(c1cc(ccc1)C(=O)N[C@H]([C@H](O)C[NH2+][C@H](C(=O)NC1CCCCC1)C)Cc1ccccc1)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O1c2ncc(cc2[C@@H]([NH2+]C[C@@H](O)[C@@H](NC(=O)[C@H](OC)C)Cc2cc3OCOc3cc2)CC12CCC2)CC(C)(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O1c2ncc(cc2[C@@H]([NH2+]C[C@@H](O)[C@@H](NC(=O)[C@H](OC)C)Cc2cc3OCOc3cc2)CC12CCC2)CC(C)(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O1c2c(cc(cc2)CC)[C@@H]([NH2+]C[C@@H](O)[C@H]2NC(=O)CCCCCCc3cc(C2)ccc3)CC12CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O1c2c(cc(cc2)CC)[C@@H]([NH2+]C[C@@H](O)[C@H]2NC(=O)CCCCCCc3cc(C2)ccc3)CC12CCC2 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1c2cc(ccc2n(c1)C(=O)N(CCCC)C)C#N)[C@H](O)C[NH2+]Cc1cc(OC)ccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1c2cc(ccc2n(c1)C(=O)N(CCCC)C)C#N)[C@H](O)C[NH2+]Cc1cc(OC)ccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@@H](C1)C(F)(F)F)N)CF shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@@H](C1)C(F)(F)F)N)CF shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1(=O)(=O)N(c2c(CCC1)c(NCC)cc(c2)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1(=O)(=O)N(c2c(CCC1)c(NCC)cc(c2)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(cc1-c1cncnc1)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)(F)F)cc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(cc1-c1cncnc1)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)(F)F)cc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1ccc(F)cc1-c1cc(ccc1)[C@]1(N=C(N)N(C)C1=O)c1ccncc1 displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(F)cc1-c1cc(ccc1)[C@]1(N=C(N)N(C)C1=O)c1ccncc1 displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(N2CCCC2=O)c2c(n(cc2)CC)c1)CC=1CCC=CC=1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(N2CCCC2=O)c2c(n(cc2)CC)c1)CC=1CCC=CC=1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1(F)F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1(F)F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Clc1cc(ccc1)-c1cc2c(OC(C[C@@]23N=C(N)N(C)C3=O)(C)C)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Clc1cc(ccc1)-c1cc2c(OC(C[C@@]23N=C(N)N(C)C3=O)(C)C)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3N(CCN(CC1)c23)CC)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S1(=O)(=O)N(c2cc(cc3N(CCN(CC1)c23)CC)C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OC[C@@H]1F)N)C displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OC[C@@H]1F)N)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O=C1N(C)C(=N[C@]1(c1cc(nc(c1)CC)CC)c1cc(ccc1)-c1cncnc1)N displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O=C1N(C)C(=N[C@]1(c1cc(nc(c1)CC)CC)c1cc(ccc1)-c1cncnc1)N displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O=C1N(CCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+]C(CCCC(C)C)(C)C)Cc1ccccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O=C1N(CCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+]C(CCCC(C)C)(C)C)Cc1ccccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](C(C)C)C(=O)Nc1cc(cc(c1)C(=O)[O-])C(=O)[O-])COc1cc(F)cc(F)c1)C(=O)N[C@H](C)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](C(C)C)C(=O)Nc1cc(cc(c1)C(=O)[O-])C(=O)[O-])COc1cc(F)cc(F)c1)C(=O)N[C@H](C)c1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of FC(F)(F)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(N2CCCC2=O)cc(NCC)c1)Cc1ccccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of FC(F)(F)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(N2CCCC2=O)cc(NCC)c1)Cc1ccccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O(C)c1ccc(cc1C)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O(C)c1ccc(cc1C)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@@H](C(F)(F)F)[C@@H]1F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(O[C@@H](C(F)(F)F)[C@@H]1F)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1c(cccc1OC)-c1cc(ccc1)[C@]1([NH+]=C(N2CC(F)(F)CN=C12)N)c1ccncc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1c(cccc1OC)-c1cc(ccc1)[C@]1([NH+]=C(N2CC(F)(F)CN=C12)N)c1ccncc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O=C(N[C@H]([C@H](O)C[NH2+][C@H]1CC(Cc2nn(cc12)CC(C)(C)C)(C)C)Cc1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O=C(N[C@H]([C@H](O)C[NH2+][C@H]1CC(Cc2nn(cc12)CC(C)(C)C)(C)C)Cc1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)C)[C@H](O)C[NH2+]C1(CCCCC1)c1cc(ccc1)C(C)(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)C)[C@H](O)C[NH2+]C1(CCCCC1)c1cc(ccc1)C(C)(C)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O(C(C)(C)C)C(=O)N[C@@H](C(C)C)C(=O)N([C@@H](CCC(=O)N)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N([C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(OC)=O)C)C)Cc1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O(C(C)(C)C)C(=O)N[C@@H](C(C)C)C(=O)N([C@@H](CCC(=O)N)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N([C@H](Cc1ccccc1)C(=O)N1CCC[C@@H]1C(OC)=O)C)C)Cc1ccccc1)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1(F)F)N)CF displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1(F)F)N)CF displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1)N)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(CC[C@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)C(=O)N[C@H]([C@@H](O)C[C@H](C(=O)NCCCC)C)CC(C)C)C displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(CC[C@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)C(=O)N[C@H]([C@@H](O)C[C@H](C(=O)NCCCC)C)CC(C)C)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1)N)C(F)F shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OCC1)N)C(F)F shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O=C1N(CC[C@]12[N@H+](CCC2)CCC)[C@H](C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)C(C)C)Cc1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O=C1N(CC[C@]12[N@H+](CCC2)CCC)[C@H](C(=O)N[C@H]([C@H](O)C[NH2+]Cc1cc(ccc1)C(C)C)Cc1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1(=O)(=O)C[C@@H](Cc2cc3c([nH]cc3CC(F)F)cc2)[C@H](O)[C@@H]([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1(=O)(=O)C[C@@H](Cc2cc3c([nH]cc3CC(F)F)cc2)[C@H](O)[C@@H]([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N([C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(OC)=O)C)C)Cc1ccccc1)C(=O)N[C@H](C)c1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N([C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(OC)=O)C)C)Cc1ccccc1)C(=O)N[C@H](C)c1ccccc1)C displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)C)[C@H](O)C[NH2+]C1(CCCCC1)c1cc(-n2nccc2)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)C)[C@H](O)C[NH2+]C1(CCCCC1)c1cc(-n2nccc2)ccc1 displays inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O=C1N(C)C(=N[C@@]1(c1cc(ccc1)-c1cccnc1)c1ccncc1)N displays inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O=C1N(C)C(=N[C@@]1(c1cc(ccc1)-c1cccnc1)c1ccncc1)N displays inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of s1cc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of s1cc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O=C(N)CC[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](O)C)C(C)C)C)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N([C@H](CC1CCCCC1)C(=O)[O-])C)C)CC1CCCCC1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O=C(N)CC[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](O)C)C(C)C)C)C(=O)N[C@H]([C@@H](O)CC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N([C@H](CC1CCCCC1)C(=O)[O-])C)C)CC1CCCCC1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of FC(F)(F)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)C=1C=C(N2CCCC2=O)C(=O)N(C=1)C1CCCC1)Cc1ccccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of FC(F)(F)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)C=1C=C(N2CCCC2=O)C(=O)N(C=1)C1CCCC1)Cc1ccccc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OC[C@@H]1F)N)CF shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OC[C@@H]1F)N)CF shows inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of FC1(F)CN2C(=NC1)[C@]([NH+]=C2N)(c1cc(ccc1)C#CCOC)c1ccc(OC(F)F)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of FC1(F)CN2C(=NC1)[C@]([NH+]=C2N)(c1cc(ccc1)C#CCOC)c1ccc(OC(F)F)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O=C1N(C)C(=N[C@@]1(c1cc(ccc1)-c1cncnc1)c1cn(nc1)CC)N shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O=C1N(C)C(=N[C@@]1(c1cc(ccc1)-c1cncnc1)c1cn(nc1)CC)N shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O1c2c(cc(cc2)-c2cc(ccc2)C#N)[C@]2(N=C(N)N(C)C2=O)CC1(C)C shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O1c2c(cc(cc2)-c2cc(ccc2)C#N)[C@]2(N=C(N)N(C)C2=O)CC1(C)C shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1c2c(n(c1)C(=O)N(CCCC)CCCC)cccc2)Cc1ccccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1c2c(n(c1)C(=O)N(CCCC)CCCC)cccc2)Cc1ccccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@H](O)C[NH2+]C1CC1)Cc1ccccc1)C(=O)c1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)N[C@H]([C@H](O)C[NH2+]C1CC1)Cc1ccccc1)C(=O)c1ccccc1)C exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of S1(=O)(=O)N([C@]2(C[C@@H]([N@H+](CC2)Cc2cc(OC(C)C)c(O)cc2)C)CN1C)c1cc(F)ccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of S1(=O)(=O)N([C@]2(C[C@@H]([N@H+](CC2)Cc2cc(OC(C)C)c(O)cc2)C)CN1C)c1cc(F)ccc1 exhibits inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Clc1ccccc1-c1n(Cc2nc(N)ccc2)c(cc1)-c1ccc(Oc2cncnc2)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Clc1ccccc1-c1n(Cc2nc(N)ccc2)c(cc1)-c1ccc(Oc2cncnc2)cc1 shows inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]CC[N@@H+](C1)Cc1ccccc1 displays no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1cc(cc(F)c1)C[C@H](NC(=O)c1cc(cc(c1)C)C(=O)N(CCC)CCC)[C@H](O)[C@@H]1[NH2+]CC[N@@H+](C1)Cc1ccccc1 displays no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1(=O)(=O)C[C@@H](Cc2cc(F)c3NCC4(CCC(F)(F)CC4)c3c2)[C@H](O)[C@@H]([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 displays no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1(=O)(=O)C[C@@H](Cc2cc(F)c3NCC4(CCC(F)(F)CC4)c3c2)[C@H](O)[C@@H]([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 displays no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O=C(N1CC[C@H](C[C@H]1c1ccccc1)c1ccccc1)[C@@H]1C[NH2+]C[C@]12CCCc1c2cccc1 shows no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O=C(N1CC[C@H](C[C@H]1c1ccccc1)c1ccccc1)[C@@H]1C[NH2+]C[C@]12CCCc1c2cccc1 shows no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1(=O)(=O)C[C@@H](Cc2cc(C[C@@H]3N(CCC)C(OC3)=O)c(O)cc2)[C@H](O)[C@@H]([NH2+]Cc2cc(ccc2)C(C)C)C1 shows no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1(=O)(=O)C[C@@H](Cc2cc(C[C@@H]3N(CCC)C(OC3)=O)c(O)cc2)[C@H](O)[C@@H]([NH2+]Cc2cc(ccc2)C(C)C)C1 shows no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1C[C@H](NC(OC(C)(C)C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CSC\C=C\C1)[C@@H](O)C[C@H](C(=O)N[C@@H](C(C)C)C(=O)NCCCC)C displays no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1C[C@H](NC(OC(C)(C)C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CSC\C=C\C1)[C@@H](O)C[C@H](C(=O)N[C@@H](C(C)C)C(=O)NCCCC)C displays no inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O(C)c1ccc(cc1C)[C@@]1(N=C(N)N(C)C1=O)C12CC3CC(C1)CC(C2)C3 exhibits no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O(C)c1ccc(cc1C)[C@@]1(N=C(N)N(C)C1=O)C12CC3CC(C1)CC(C2)C3 exhibits no inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Clc1cc2CC([NH+]=C(N[C@@H](Cc3ccccc3)C=3NC(=O)c4c(N=3)ccnc4)c2cc1)(C)C displays no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Clc1cc2CC([NH+]=C(N[C@@H](Cc3ccccc3)C=3NC(=O)c4c(N=3)ccnc4)c2cc1)(C)C displays no inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O=C1N(CCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+]C1CCCCC1)Cc1ccccc1 shows no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O=C1N(CCC1)c1cc(cc(NCC)c1)C(=O)N[C@H]([C@H](O)C[NH2+]C1CCCCC1)Cc1ccccc1 shows no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(OCC)cc2)cc1[C@]1(N=C(OCC1(F)F)N)C shows no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(NC(=O)c2ncc(OCC)cc2)cc1[C@]1(N=C(OCC1(F)F)N)C shows no inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O(C(=O)[C@H]1N(CCC1)C(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C[C@H](O)[C@@H](NC(=O)[C@@H](N(C(=O)[C@@H](NC(=O)[C@@H](O)C)C(C)C)C)CCC(=O)N)CC1CCCCC1)CC(C)C)C)C)CC1CCCCC1)C shows no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O(C(=O)[C@H]1N(CCC1)C(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C[C@H](O)[C@@H](NC(=O)[C@@H](N(C(=O)[C@@H](NC(=O)[C@@H](O)C)C(C)C)C)CCC(=O)N)CC1CCCCC1)CC(C)C)C)C)CC1CCCCC1)C shows no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of S1C[C@H](NC(=O)[C@@H](NC(=O)[C@@H]2[NH2+]CCC[C@@H]2SC\C=C\C1)C)[C@@H](O)C[C@H](C(=O)NCCCC)C exhibits no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S1C[C@H](NC(=O)[C@@H](NC(=O)[C@@H]2[NH2+]CCC[C@@H]2SC\C=C\C1)C)[C@@H](O)C[C@H](C(=O)NCCCC)C exhibits no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(ccc1)C(=O)N(CCC)CCC)Cc1ccccc1 shows no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of O(C)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(ccc1)C(=O)N(CCC)CCC)Cc1ccccc1 shows no inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of O=C(NC[C@H]([NH3+])C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NC[C@](O)(CCc1ccccc1)C(=O)Nc1cc(ccc1)C(=O)[O-])c1nnn[n-]1 exhibits no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O=C(NC[C@H]([NH3+])C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NC[C@](O)(CCc1ccccc1)C(=O)Nc1cc(ccc1)C(=O)[O-])c1nnn[n-]1 exhibits no inhibition of the human beta-secretase 1 (BACE-1).
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The compound with the SMILES of Fc1ccc(cc1-c1cncnc1)[C@]1([NH+]=C(N)c2c1cccc2F)c1cc(ncc1)C(F)(F)F displays no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Fc1ccc(cc1-c1cncnc1)[C@]1([NH+]=C(N)c2c1cccc2F)c1cc(ncc1)C(F)(F)F displays no inhibition of the human beta-secretase 1 (BACE-1).
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null
The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(OC[C@]([NH3+])(Cc1ccccc1)CO)=O)C(=O)N[C@H](C)c1ccc(F)cc1)C shows no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of S(=O)(=O)(N(C)c1cc(cc(c1)C(OC[C@]([NH3+])(Cc1ccccc1)CO)=O)C(=O)N[C@H](C)c1ccc(F)cc1)C shows no inhibition of the human beta-secretase 1 (BACE-1).
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null
The chemical with the SMILES of FC(F)(F)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(N2CCCC2=O)c2nccc(c2c1)CC)Cc1ccccc1 displays no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of FC(F)(F)c1cc(ccc1)C[NH2+]C[C@@H](O)[C@@H](NC(=O)c1cc(N2CCCC2=O)c2nccc(c2c1)CC)Cc1ccccc1 displays no inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of Clc1cc(-c2cc3c(Oc4c(cc(OC)cc4)[C@@]34N=C(OC4)N)cc2)c(F)cc1 exhibits no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Clc1cc(-c2cc3c(Oc4c(cc(OC)cc4)[C@@]34N=C(OC4)N)cc2)c(F)cc1 exhibits no inhibition of the human beta-secretase 1 (BACE-1).
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null
The compound with the SMILES of Brc1cscc1C[C@H](NC1=[NH+]C(Cc2c1ccc(Cl)c2)(C)C)C(=O)[O-] exhibits no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Brc1cscc1C[C@H](NC1=[NH+]C(Cc2c1ccc(Cl)c2)(C)C)C(=O)[O-] exhibits no inhibition of the human beta-secretase 1 (BACE-1).
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null
The compound with the SMILES of Clc1ccc(nc1)C(=O)Nc1cc(ccc1)[C@]1([NH+]=C(N)CN(C)C1=O)C displays no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Clc1ccc(nc1)C(=O)Nc1cc(ccc1)[C@]1([NH+]=C(N)CN(C)C1=O)C displays no inhibition of the human beta-secretase 1 (BACE-1).
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null
The chemical with the SMILES of O(C)c1cc(ccc1)-c1cc(ccc1)[C@]1(N=C(N)N(C)C(=O)C1)C shows no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of O(C)c1cc(ccc1)-c1cc(ccc1)[C@]1(N=C(N)N(C)C(=O)C1)C shows no inhibition of the human beta-secretase 1 (BACE-1).
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null
The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OC[C@H]1F)N)C shows no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of Fc1ccc(NC(=O)c2ncc(cc2)C#N)cc1[C@]1(N=C(OC[C@H]1F)N)C shows no inhibition of the human beta-secretase 1 (BACE-1).
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null
The compound with the SMILES of Clc1cc2CC([NH+]=C(N[C@@H](Cc3ccccc3)C=3NC(=O)C(=CN=3)C#N)c2cc1)(C)C displays no inhibition of the human beta-secretase 1 (BACE-1).
The compound with the SMILES of Clc1cc2CC([NH+]=C(N[C@@H](Cc3ccccc3)C=3NC(=O)C(=CN=3)C#N)c2cc1)(C)C displays no inhibition of the human beta-secretase 1 (BACE-1).
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The chemical with the SMILES of s1cc(cc1C1([NH2+]C[C@@H](O)[C@@H](NC(=O)C)Cc2cc(F)cc(F)c2)CC1)CC(C)(C)C displays no inhibition of the human beta-secretase 1 (BACE-1).
The chemical with the SMILES of s1cc(cc1C1([NH2+]C[C@@H](O)[C@@H](NC(=O)C)Cc2cc(F)cc(F)c2)CC1)CC(C)(C)C displays no inhibition of the human beta-secretase 1 (BACE-1).
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