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The epivodes of NMS occured under treatment with clozapine, risperidone, and amisulpride. | [
{
"ade": "NMS",
"drug": "amisulpride"
},
{
"ade": "NMS",
"drug": "risperidone"
},
{
"ade": "NMS",
"drug": "clozapine"
}
] |
We report a case of hyperpigmentation due to bleomycin treatment in a patient with acquired immune deficiency syndrome (AIDS). | [
{
"ade": "hyperpigmentation",
"drug": "bleomycin"
}
] |
After the chlorambucil was discontinued, the wbc count began to slowly rise and the patient developed clinical AML. | [
{
"ade": "AML",
"drug": "chlorambucil"
}
] |
Pancytopenia associated with 5-aminosalicylic acid use in a patient with Crohn's disease. | [
{
"ade": "Pancytopenia",
"drug": "5-aminosalicylic acid"
}
] |
Acute pulmonary reactions to nitrofurantoin are an uncommon side effect of therapy and can cause minor or life-threatening pulmonary dysfunction. | [
{
"ade": "Acute pulmonary reactions",
"drug": "nitrofurantoin"
},
{
"ade": "pulmonary dysfunction",
"drug": "nitrofurantoin"
}
] |
The allopurinol hypersensitivity syndrome is a rare adverse drug reaction. | [
{
"ade": "hypersensitivity syndrome",
"drug": "allopurinol"
}
] |
Pulmonary fibrosis is a severe complication associated with bis-chloronitrosourea (BCNU) therapy. | [
{
"ade": "Pulmonary fibrosis",
"drug": "BCNU"
},
{
"ade": "Pulmonary fibrosis",
"drug": "bis-chloronitrosourea"
}
] |
Renal failure after high-dose methotrexate in a child homozygous for MTHFR C677T polymorphism. | [
{
"ade": "Renal failure",
"drug": "methotrexate"
}
] |
Interaction between tacrolimus and nefazodone in a stable renal transplant recipient. | [
{
"ade": "Interaction",
"drug": "tacrolimus"
},
{
"ade": "Interaction",
"drug": "nefazodone"
}
] |
Cyclosporin side effects included hirsutism, hypertension, increased blood levels of urea and creatinine, and abnormalities in liver function tests. | [
{
"ade": "abnormalities in liver function tests",
"drug": "Cyclosporin"
},
{
"ade": "hypertension",
"drug": "Cyclosporin"
},
{
"ade": "increased blood levels of urea and creatinine",
"drug": "Cyclosporin"
},
{
"ade": "hirsutism",
"drug": "Cyclosporin"
}
] |
OBJECTIVE: To report a case of linear immunoglobulin (Ig) A bullous dermatosis (LABD) induced by gemcitabine. | [
{
"ade": "LABD",
"drug": "gemcitabine"
},
{
"ade": "linear immunoglobulin (Ig) A bullous dermatosis",
"drug": "gemcitabine"
}
] |
Secretory endometrial adenocarcinoma in a patient on tamoxifen for breast cancer: a report of a case. | [
{
"ade": "Secretory endometrial adenocarcinoma",
"drug": "tamoxifen"
}
] |
ARDS is rarely associated with rituximab infusion for lympho-proliferative disorders, but it should be considered by those administering rituximab, especially when a patient develops severe pulmonary symptoms soon after infusion. | [
{
"ade": "ARDS",
"drug": "rituximab"
},
{
"ade": "severe pulmonary symptoms",
"drug": "rituximab"
}
] |
After administration of Oxybutynin concomitantly with an increase in the dose of Dantrolene, she presented the clinical symptoms and laboratory finding of Carbamazepine intoxication. | [
{
"ade": "Carbamazepine intoxication",
"drug": "Dantrolene"
},
{
"ade": "Carbamazepine intoxication",
"drug": "Carbamazepine"
},
{
"ade": "Carbamazepine intoxication",
"drug": "Oxybutynin"
}
] |
Fulminant liver failure associated with clarithromycin. | [
{
"ade": "Fulminant liver failure",
"drug": "clarithromycin"
}
] |
Posterior leukoencephalopathy following cisplatin, bleomycin and vinblastine therapy for germ cell tumor of the ovary. | [
{
"ade": "Posterior leukoencephalopathy",
"drug": "vinblastine"
},
{
"ade": "Posterior leukoencephalopathy",
"drug": "cisplatin"
},
{
"ade": "Posterior leukoencephalopathy",
"drug": "bleomycin"
}
] |
We report a case of Zidovudine induced anaemia and bone marrow aplasia in a patient infected with HIV. | [
{
"ade": "anaemia",
"drug": "Zidovudine"
},
{
"ade": "bone marrow aplasia",
"drug": "Zidovudine"
}
] |
We report a case of hepatolithiasis (intrahepatic stone) complicated by gram-negative sepsis in a 37 year old male with acromegaly being treated with octreotide. | [
{
"ade": "hepatolithiasis",
"drug": "octreotide"
}
] |
Liver disease induced by perhexiline maleate. | [
{
"ade": "Liver disease",
"drug": "perhexiline maleate"
}
] |
There are no previous reports in the literature about the emergence of CML during treatment with hydroxyurea. | [
{
"ade": "CML",
"drug": "hydroxyurea"
}
] |
We report a 50-year-old male patient with a 15-year history of psoriasis including mutilating psoriatic arthritis, in whom the withdrawal of cyclosporin A induced a generalised pustular exacerbation and a aggravation of the joint condition. | [
{
"ade": "aggravation of the joint condition",
"drug": "cyclosporin A"
},
{
"ade": "generalised pustular exacerbation",
"drug": "cyclosporin A"
}
] |
RESULTS: Evidence of neurological improvement and rehabilitation potential after severe myelopathy due to intrathecal injection of doxorubicin. | [
{
"ade": "severe myelopathy",
"drug": "doxorubicin"
}
] |
We describe a case of EGE manifested as an allergy to gemfibrozil. | [
{
"ade": "EGE",
"drug": "gemfibrozil"
}
] |
Schneiderian first-rank symptoms associated with fluvoxamine treatment: a case report. | [
{
"ade": "Schneiderian first-rank symptoms",
"drug": "fluvoxamine"
}
] |
Although the literature on the use of risperidone in elderly patients with dementia consists largely of uncontrolled trials, case reports, and chart reviews, it appears that this agent is effective for managing agitation in this population and does so with a low frequency of extrapyramidal symptoms (EPS). | [
{
"ade": "EPS",
"drug": "risperidone"
},
{
"ade": "extrapyramidal symptoms",
"drug": "risperidone"
}
] |
A 61 year-old male patient developed gynecomastia after starting theophylline. | [
{
"ade": "gynecomastia",
"drug": "theophylline"
}
] |
Recurrent septicemia with lethal outcome during and after cyclosporine therapy in severe ulcerative colitis. | [
{
"ade": "lethal",
"drug": "cyclosporine"
},
{
"ade": "septicemia",
"drug": "cyclosporine"
}
] |
Thyroid dysfunction has been reported in patients with malignant disease treated with recombinant alpha interferon. | [
{
"ade": "Thyroid dysfunction",
"drug": "recombinant alpha interferon"
}
] |
Spontaneous bacterial peritonitis induced by intraarterial vasopressin therapy. | [
{
"ade": "bacterial peritonitis",
"drug": "vasopressin"
}
] |
RESULTS: After 4- to 14-month period of therapy with the combination of indapamide (2.5 mg/day) and fosinopril (10 mg/day) in three patients and 6-month period of monotherapy with indapamide (2.5 mg/day) in one patient, glucose levels of all patients increased and achieve criteria of diabetes diagnoses. | [
{
"ade": "diabetes",
"drug": "indapamide"
},
{
"ade": "diabetes",
"drug": "fosinopril"
}
] |
We present a case of cutaneous leucocytoclastic vasculitis in which amphotericin B might presumably be the aetiological factor. | [
{
"ade": "cutaneous leucocytoclastic vasculitis",
"drug": "amphotericin B"
}
] |
CONCLUSIONS: Priapism is an uncommon but potentially serious adverse effect of zuclopenthixol that practitioners, as with many other antipsychotics, should be aware of. | [
{
"ade": "Priapism",
"drug": "zuclopenthixol"
}
] |
The delayed encephalopathy developed 9 and 22 months respectively after the first dose of intrathecal methotrexate. | [
{
"ade": "encephalopathy",
"drug": "methotrexate"
}
] |
Four cases of oesophageal damage associated with ingestion of the urinary anti-spasmodic agent emepronium bromide are described. | [
{
"ade": "oesophageal damage",
"drug": "emepronium bromide"
}
] |
Here we report a patient with newly diagnosed acute promyelocytic leukemia who developed acute focal myositis, synovitis, and possible vasculitis, after receiving all-trans retinoic acid therapy. | [
{
"ade": "acute focal myositis",
"drug": "all-trans retinoic acid"
},
{
"ade": "synovitis",
"drug": "all-trans retinoic acid"
},
{
"ade": "possible vasculitis",
"drug": "all-trans retinoic acid"
}
] |
Because nephrotic syndrome may be induced by IFN therapy, the IFN was stopped. | [
{
"ade": "nephrotic syndrome",
"drug": "IFN"
}
] |
In this case, it was suspected that a combination of cigarette smoking, pulmonary fibrosis, and low-dose methotrexate therapy might have promoted the development of lung cancer. | [
{
"ade": "lung cancer",
"drug": "methotrexate"
}
] |
CASE SUMMARY: A 45-year-old HIV-positive man (CD4+ count 450 cells/mm(3) and history of AIDS-defining illness) presented with JHR after an initial intravenous dose of penicillin G for presumed neurosyphilis. | [
{
"ade": "JHR",
"drug": "penicillin G"
}
] |
Management and successful desensitization in methotrexate-induced anaphylaxis. | [
{
"ade": "anaphylaxis",
"drug": "methotrexate"
}
] |
Cutaneous vasculitis secondary to ramipril. | [
{
"ade": "Cutaneous vasculitis",
"drug": "ramipril"
}
] |
CASE SUMMARY: We report the case of a 31-year-old patient hospitalized due to behavioral alterations and treated with oral zuclopenthixol, an antipsychotic from the thioxanthene family, who developed an acute, painful erection. | [
{
"ade": "painful erection",
"drug": "zuclopenthixol"
}
] |
The patient completed a 10-month follow-up, maintaining a complete resolution of the treated skin lesions; however, the development of a painful hand ulcer, possibly associated with the hydroxyurea, and new skin cancers were observed at the last follow-up visit. | [
{
"ade": "skin cancers",
"drug": "hydroxyurea"
},
{
"ade": "painful hand ulcer",
"drug": "hydroxyurea"
}
] |
Drug-induced fever due to diltiazem. | [
{
"ade": "fever",
"drug": "diltiazem"
}
] |
Because sumatriptan can cause coronary artery vasospasm, patients with significant risk factors for coronary artery disease should be carefully evaluated for cardiovascular disease prior to the use of sumatriptan. | [
{
"ade": "coronary artery vasospasm",
"drug": "sumatriptan"
}
] |
Gemcitabine-associated hemolytic-uremic syndrome. | [
{
"ade": "hemolytic-uremic syndrome",
"drug": "Gemcitabine"
}
] |
We experienced 2 cases of mequitazine-induced photosensitivity reaction in patients who took mequitazine for their dermatologic problems. | [
{
"ade": "photosensitivity reaction",
"drug": "mequitazine"
}
] |
The development of systemic lupus erythematosus (SLE) after 38 months of therapy with recombinant human interferon gamma (rIFN-gamma) was observed in a patient with rheumatoid arthritis. | [
{
"ade": "SLE",
"drug": "recombinant human interferon gamma"
},
{
"ade": "systemic lupus erythematosus",
"drug": "rIFN-gamma"
},
{
"ade": "systemic lupus erythematosus",
"drug": "recombinant human interferon gamma"
},
{
"ade": "SLE",
"drug": "rIFN-gamma"
}
] |
Previous studies have demonstrated the interaction of MTX and a variety of non-steroidal, anti-inflammatory drugs (NSAIDs) with various clinical manifestations including acute renal failure, pancytopenia, vomiting, diarrhea, elevated liver transaminases, jaundice, mucosal ulcerations, and pyrexia. | [
{
"ade": "diarrhea",
"drug": "MTX"
},
{
"ade": "pyrexia",
"drug": "MTX"
},
{
"ade": "acute renal failure",
"drug": "MTX"
},
{
"ade": "vomiting",
"drug": "MTX"
},
{
"ade": "mucosal ulcerations",
"drug": "MTX"
},
{
"ade": "jaundice",
"drug": "MTX"
},
{
"ade": "pancytopenia",
"drug": "MTX"
},
{
"ade": "elevated liver transaminases",
"drug": "MTX"
}
] |
The case reported here is of a child given a large dose of intravenous iron sucrose (16 mg/kg) over 3 hours, who subsequently developed features of systemic iron toxicity. | [
{
"ade": "systemic iron toxicity",
"drug": "iron sucrose"
}
] |
In the present paper the authors describe 2 female patients who developed incontinence secondary to the selective serotonin reuptake inhibitors paroxetine and sertraline, as well as a third who developed this side effect on venlafaxine. | [
{
"ade": "incontinence",
"drug": "venlafaxine"
},
{
"ade": "incontinence",
"drug": "paroxetine"
},
{
"ade": "incontinence",
"drug": "sertraline"
}
] |
Six patients with no previous signs or symptoms suggestive of coronary artery disease developed acute coronary ischemia/infarction shortly after cis-diamine-dichloroplatinum II (cisplatin) -based chemotherapy. | [
{
"ade": "acute coronary ischemia",
"drug": "cis-diamine-dichloroplatinum II"
},
{
"ade": "infarction",
"drug": "cisplatin"
},
{
"ade": "infarction",
"drug": "cis-diamine-dichloroplatinum II"
},
{
"ade": "acute coronary ischemia",
"drug": "cisplatin"
}
] |
An 8-year-old child with familial Mediterranean fever exhibited signs of colchicine intoxication while receiving prophylactic doses of the drug. | [
{
"ade": "colchicine intoxication",
"drug": "colchicine"
}
] |
Gastro-oesophageal reflux associated with nifedipine. | [
{
"ade": "Gastro-oesophageal reflux",
"drug": "nifedipine"
}
] |
A further case of anaphylactoid reaction to methylprednisolone is reported. | [
{
"ade": "anaphylactoid reaction",
"drug": "methylprednisolone"
}
] |
We present the first case of ovarian endometrioid carcinoma and endometriosis in a postmenopausal patient who was treated with tamoxifen for breast cancer. | [
{
"ade": "endometriosis",
"drug": "tamoxifen"
},
{
"ade": "ovarian endometrioid carcinoma",
"drug": "tamoxifen"
}
] |
Posthypoglycemic hyperglycemia (rebound hyperglycemia) after overdosing of insulin was diagnosed in 6 cats with diabetes mellitus. | [
{
"ade": "Posthypoglycemic hyperglycemia",
"drug": "insulin"
},
{
"ade": "rebound hyperglycemia",
"drug": "insulin"
}
] |
A patient with chronic myelomonocytic leukemia developed drug-induced pulmonary toxicity after using low dose oral etoposide. | [
{
"ade": "pulmonary toxicity",
"drug": "etoposide"
}
] |
Use of the Naranjo probability scale determined the association between cephalosporin use and leukopenia to be probable. | [
{
"ade": "leukopenia",
"drug": "cephalosporin"
}
] |
A 77-year-old man developed ankle, hand, and facial swelling 2 weeks after starting rosiglitazone. | [
{
"ade": "ankle, hand, and facial swelling",
"drug": "rosiglitazone"
}
] |
Fatal digoxin poisoning: an unsuccessful resuscitation with use of digoxin-immune Fab. | [
{
"ade": "Fatal digoxin poisoning",
"drug": "digoxin"
}
] |
Thrombocytosis under ciprofloxacin and tazobactam/piperacillin. | [
{
"ade": "Thrombocytosis",
"drug": "tazobactam"
},
{
"ade": "Thrombocytosis",
"drug": "piperacillin"
},
{
"ade": "Thrombocytosis",
"drug": "ciprofloxacin"
}
] |
This report describes a case of acute compromise of renal function associated with hypotension in a 7-year-old boy treated with the ACE inhibitor lisinopril and the ARB losartan. | [
{
"ade": "hypotension",
"drug": "lisinopril"
},
{
"ade": "hypotension",
"drug": "losartan"
}
] |
Severe autoimmune hemolytic anemia following rituximab therapy in a patient with a lymphoproliferative disorder. | [
{
"ade": "autoimmune hemolytic anemia",
"drug": "rituximab"
}
] |
She was admitted following a fall and, after being given metoclopramide, developed movement disorder and a period of unresponsiveness. | [
{
"ade": "movement disorder",
"drug": "metoclopramide"
},
{
"ade": "unresponsiveness",
"drug": "metoclopramide"
}
] |
Basilar invagination and mid-line skeletal abnormalities due to in utero exposure to phenytoin. | [
{
"ade": "mid-line skeletal abnormalities",
"drug": "phenytoin"
},
{
"ade": "Basilar invagination",
"drug": "phenytoin"
}
] |
The patient was given methimazole instead of propylthiouracil but, 10 weeks later, agranulocytosis again occurred. | [
{
"ade": "agranulocytosis",
"drug": "methimazole"
}
] |
Psoriasis-like skin reaction in a patient with rheumatoid arthritis after sulphasalazine therapy. | [
{
"ade": "Psoriasis-like skin reaction",
"drug": "sulphasalazine"
}
] |
Valproic acid induced coma is presented in an adult patient without a history of metabolic disease. | [
{
"ade": "coma",
"drug": "Valproic acid"
}
] |
A 15-kg weight gain developed in a patient during the third week of ibuprofen therapy. | [
{
"ade": "15-kg weight gain",
"drug": "ibuprofen"
}
] |
The cause of death was determined to be acute intoxication by olanzapine, and the manner of death was accidental. | [
{
"ade": "acute intoxication",
"drug": "olanzapine"
}
] |
We report 5 cases of acute reversible renal failure coinciding with the onset of treatment with captopril in patients with severe drug-resistant hypertension. | [
{
"ade": "acute reversible renal failure",
"drug": "captopril"
}
] |
Massive prolapse of the urethral mucosa following periurethral injection of calcium hydroxylapatite for stress urinary incontinence. | [
{
"ade": "prolapse of the urethral mucosa",
"drug": "calcium hydroxylapatite"
}
] |
Methotrexate-induced hepatic necrosis requiring liver transplantation in a patient with rheumatoid arthritis. | [
{
"ade": "hepatic necrosis",
"drug": "Methotrexate"
}
] |
However, re-initiation of sunitinib treatment was followed by bilateral breast enlargement again. | [
{
"ade": "bilateral breast enlargement",
"drug": "sunitinib"
}
] |
We report the first case of a patient in a promethazine-induced coma responding to treatment with flumazenil. | [
{
"ade": "coma",
"drug": "promethazine"
}
] |
Methimazole-induced aplastic anemia in third exposure: successful treatment with recombinant human granulocyte colony-stimulating factor. | [
{
"ade": "aplastic anemia",
"drug": "Methimazole"
}
] |
We describe a patient with transitional cell carcinoma of the renal pelvis who developed respiratory dysfunction and an abnormal chest x-ray with diffuse interstitial opacities while on chemotherapy with piritrexim, a methotrexate analog. | [
{
"ade": "abnormal chest x-ray with diffuse interstitial opacities",
"drug": "piritrexim"
},
{
"ade": "respiratory dysfunction",
"drug": "piritrexim"
}
] |
Physicians who use sulfasalazine to treat patients with inflammatory bowel disease should be aware of the signs of sulfasalazine-induced lupus syndrome. | [
{
"ade": "lupus syndrome",
"drug": "sulfasalazine"
}
] |
Bortezomib-induced paralytic ileus is a potential gastrointestinal side effect of this first-in-class anticancer proteasome inhibitor. | [
{
"ade": "gastrointestinal side effect",
"drug": "Bortezomib"
},
{
"ade": "paralytic ileus",
"drug": "Bortezomib"
}
] |
Our patient had headache, mild fever, nausea, vomiting, rash, and eosinophilia after 3 weeks of disulfiram therapy. | [
{
"ade": "headache",
"drug": "disulfiram"
},
{
"ade": "nausea",
"drug": "disulfiram"
},
{
"ade": "rash",
"drug": "disulfiram"
},
{
"ade": "mild fever",
"drug": "disulfiram"
},
{
"ade": "eosinophilia",
"drug": "disulfiram"
},
{
"ade": "vomiting",
"drug": "disulfiram"
}
] |
The authors present an elderly patient with mixed dementia who developed TD at multiple sites, (including respiratory dyskinesia [RD], limb dyskinesia, and orofacial dyskinesia) following abrupt withdrawal of risperidone therapy. | [
{
"ade": "respiratory dyskinesia",
"drug": "risperidone"
},
{
"ade": "orofacial dyskinesia",
"drug": "risperidone"
},
{
"ade": "RD",
"drug": "risperidone"
},
{
"ade": "limb dyskinesia",
"drug": "risperidone"
},
{
"ade": "TD",
"drug": "risperidone"
}
] |
RESULTS: A patient developed a bilaterally symmetric bull's-eye maculopathy 45 years after taking quinacrine for 18 months as prophylaxis against malaria. | [
{
"ade": "bilaterally symmetric bull's-eye maculopathy",
"drug": "quinacrine"
}
] |
Although there is one case report of cholesterol crystal embolization following t-PA therapy with only extrarenal manifestations (N Engl J Med 321:1270, 1989), this is the first reported case of atheroembolic acute renal failure following t-PA therapy. | [
{
"ade": "cholesterol crystal embolization",
"drug": "t-PA"
},
{
"ade": "atheroembolic acute renal failure",
"drug": "t-PA"
},
{
"ade": "extrarenal manifestations",
"drug": "t-PA"
}
] |
Cefoxitin therapy for Mycobacterium fortuitum bacteremia with associated granulomatous hepatitis. | [
{
"ade": "granulomatous hepatitis",
"drug": "Cefoxitin"
}
] |
We report here a rare case of ritodrine-hydrochloride-induced rhabdomyolysis in a pregnant patient with myotonic dystrophy. | [
{
"ade": "rhabdomyolysis",
"drug": "ritodrine-hydrochloride"
}
] |
Reported are three children who developed progressive paraparesis after intrathecal methotrexate administration followed by complete or partial recovery. | [
{
"ade": "progressive paraparesis",
"drug": "methotrexate"
}
] |
The authors report one case of incomplete posterior hyaloid detachment (PHD) following intravitreal pegaptanib to treat DME. | [
{
"ade": "incomplete posterior hyaloid detachment",
"drug": "pegaptanib"
}
] |
This report suggests that anemia can occur due to MMF, in particular when it is given with prednisone, a side effect well documented in the transplantation literature when the triple combination of MMF, cyclosporine and prednisone is used. | [
{
"ade": "anemia",
"drug": "MMF"
},
{
"ade": "anemia",
"drug": "prednisone"
},
{
"ade": "anemia",
"drug": "cyclosporine"
}
] |
Disseminated intravascular coagulation associated with acute hemoglobinemia or hemoglobinuria following Rh(0)(D) immune globulin intravenous administration for immune thrombocytopenic purpura. | [
{
"ade": "hemoglobinuria",
"drug": "Rh(0)(D) immune globulin"
},
{
"ade": "Disseminated intravascular coagulation",
"drug": "Rh(0)(D) immune globulin"
},
{
"ade": "acute hemoglobinemia",
"drug": "Rh(0)(D) immune globulin"
}
] |
Since elevated cortisol levels in Cushing's disease poses a threat for pancreatitis, there is a possibility that patients with Cushing's disease might be more prone to acute pancreatitis following propofol administration. | [
{
"ade": "acute pancreatitis",
"drug": "propofol"
}
] |
A 50-year-old diabetic and hypertensive male patient is reported who had ticlopidine-induced marrow aplasia partially responsive to colony-stimulating factors and corticosteroids, but experienced complete recovery with cyclosporine. | [
{
"ade": "marrow aplasia",
"drug": "ticlopidine"
}
] |
It is hoped that this case report creates awareness that ofloxacin-induced toxic epidermal necrolysis is possible. | [
{
"ade": "toxic epidermal necrolysis",
"drug": "ofloxacin"
}
] |
We report a patient with chronic renal failure and ischemic heart disease who developed clinically significant methemoglobinemia after an axillary block with bupivacaine and additional injection of lidocaine in the operative field. | [
{
"ade": "methemoglobinemia",
"drug": "bupivacaine"
},
{
"ade": "methemoglobinemia",
"drug": "lidocaine"
}
] |
Therapy with IFN-alpha may be associated with a number of neuropsychiatric symptoms, such as Parkinsonism, akathisia, seizure, and depressive disorders. | [
{
"ade": "seizure",
"drug": "IFN-alpha"
},
{
"ade": "neuropsychiatric symptoms",
"drug": "IFN-alpha"
},
{
"ade": "Parkinsonism",
"drug": "IFN-alpha"
},
{
"ade": "akathisia",
"drug": "IFN-alpha"
},
{
"ade": "depressive disorders",
"drug": "IFN-alpha"
}
] |
Bradycardia and congestive heart failure associated with ocular timolol maleate. | [
{
"ade": "congestive heart failure",
"drug": "timolol maleate"
},
{
"ade": "Bradycardia",
"drug": "timolol maleate"
}
] |
Dural sinus thrombosis developed in two children with acute lymphoblastic leukemia during induction treatment with vincristine sulfate, prednisone, and asparaginase. | [
{
"ade": "Dural sinus thrombosis",
"drug": "prednisone"
},
{
"ade": "Dural sinus thrombosis",
"drug": "vincristine sulfate"
},
{
"ade": "Dural sinus thrombosis",
"drug": "asparaginase"
}
] |
Pulmonary oedema after hexoprenaline administration in preterm labour. | [
{
"ade": "Pulmonary oedema",
"drug": "hexoprenaline"
}
] |
Systemic disease, most commonly renal dysfunction, preceded all 30 reported cases of acyclovir neurotoxicity. | [
{
"ade": "neurotoxicity",
"drug": "acyclovir"
}
] |
Flumazenil reversal of benzodiazepine-induced sedation for a patient with severe pre-ECT anxiety. | [
{
"ade": "sedation",
"drug": "benzodiazepine"
}
] |
However, the occurrence and management of akathisia induced by fluvoxamine have not been described. | [
{
"ade": "akathisia",
"drug": "fluvoxamine"
}
] |
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