conclusions
string | copyrights
string | doi
string | results
string | keywords
list | publication_date
string | abstract
string | authors
list | journal
string | methods
string | pubmed_id
string | title
string | isbn
string | publication_type
string | sections
list | publisher
string | publisher_location
string | language
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
null |
© 2022. The Author(s).
|
10.1186/s13063-022-06044-y
10.1111/pan.13264
10.1111/pan.12988
10.1097/AAP.0000000000000071
10.1213/ane.0000000000003829
10.1136/rapm-2020-101496
10.1097/aap.0000000000000451
10.1016/s0196-0644(96)70238-x
10.1007/s12630-020-01875-2
| null |
[
"Erector spinae plane block",
"Pain management",
"Pectus excavatum",
"Randomized controlled trial",
"Thoracic paravertebral block"
] |
2022-02-16
|
Thoracic paravertebral block (TPVB) is a widely advocated regional technique for alleviating postoperative pain in children undergoing elective pectus excavatum repair. However, this technique is associated with some undesirable adverse events. Recently, the erector spinae plane block (ESPB) has been introduced as a practical alternative to the TPVB in thoracic surgery. This interfascial regional anesthesia technique interrupts pain sensation by injecting local anesthetics between the muscular layers of the thoracic wall. Several case series described it as an effective pain management technique following pectus excavatum repair. Therefore, this trial is designed to test the hypothesis that ESPB is non-inferior to TPVB in postoperative pain control after pectus excavatum repair.
This is a prospective randomized double-blind non-inferiority trial. A total of 40 patients aged 4 to 18 years undergoing Nuss surgery will be randomly assigned to receive pain treatment with either ESPB or TPVB. All patients will receive additional systemic multimodal analgesia with an intravenous patient-controlled analgesia pump and acetaminophen. The primary outcome is the pain intensity at rest, 24 h postoperatively. Secondary outcomes include accumulated morphine-equivalent consumption, postoperative pain scores, emergence agitation incidence, time of the first mobilization, time to first rescue analgesia, complications related to pain treatment, and morphine-related adverse events.
This will the first randomized controlled trial to compare ESPB with TPVB for analgesia after pectus excavatum repair. This trial aims to provide important clinical evidence to elaborate on the analgesic mechanism of ESPB in children.
ClinicalTrials.gov NCT05034601 . This trial was prospectively registered.
|
[
{
"affiliation": "Department of Anesthesiology and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.",
"collective": null,
"firstname": "Min",
"initials": "M",
"lastname": "Xu"
},
{
"affiliation": "Department of Anesthesiology and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China.",
"collective": null,
"firstname": "Guangchao",
"initials": "G",
"lastname": "Zhang"
},
{
"affiliation": "Department of Biomedical Engineering, Northwestern University, Evanston, IL, USA.",
"collective": null,
"firstname": "Jingxuan",
"initials": "J",
"lastname": "Gong"
},
{
"affiliation": "Department of Anesthesiology and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, Sichuan Province, China. [email protected].",
"collective": null,
"firstname": "Jing",
"initials": "J",
"lastname": "Yang"
}
] |
Trials
| null |
35164831
29063665
27510834
24682079
30346358
32817407
27501016
8604867
33403545
|
Comparison of erector spinae plane and paravertebral nerve blocks for postoperative analgesia in children after the Nuss procedure: study protocol for a randomized controlled non-inferiority clinical trial.
| null | null | null | null | null | null |
null | null |
10.1155/2019/5785189
10.1016/j.jpedsurg.2013.02.069
10.1016/j.urology.2013.02.015
10.1016/j.humpath.2012.11.005
10.1089/end.2006.0140
| null |
[] |
2019-09-29
|
A 44-year-old woman visited a hospital with microscopic hematuria in June 2009. Computed tomography showed a large bladder diverticulum at right lateral wall and urachal remnant. Cystoscopic examination showed a large diverticulum at the right lateral wall that closes to the dome. She was followed up closely without therapeutic intervention; however, the residual urine increased gradually and frequent bladder diverticulitis developed. She underwent laparoscopic bladder diverticulectomy and excision of the urachal remnant simultaneously without any complications in August 2017. Laparoscopic approach for a large bladder diverticulum and urachal remnant is useful with safe, effective, and minimally invasive.
|
[
{
"affiliation": "Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.",
"collective": null,
"firstname": "Masaki",
"initials": "M",
"lastname": "Murata"
},
{
"affiliation": "Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.",
"collective": null,
"firstname": "Kohei",
"initials": "K",
"lastname": "Inui"
},
{
"affiliation": "Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.",
"collective": null,
"firstname": "Moto",
"initials": "M",
"lastname": "Hasegawa"
},
{
"affiliation": "Department of Diagnostic Radiology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.",
"collective": null,
"firstname": "Yohei",
"initials": "Y",
"lastname": "Ikeda"
},
{
"affiliation": "Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.",
"collective": null,
"firstname": "Yuki",
"initials": "Y",
"lastname": "Nakagawa"
},
{
"affiliation": "Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.",
"collective": null,
"firstname": "Noboru",
"initials": "N",
"lastname": "Hara"
},
{
"affiliation": "Department of Urology, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.",
"collective": null,
"firstname": "Tsutomu",
"initials": "T",
"lastname": "Nishiyama"
}
] |
Case reports in urology
| null |
31559104
|
Simultaneous Laparoscopic Surgery for Bladder Diverticulum and Urachal Remnant: A Case Report.
| null | null | null | null | null | null |
The use of the SaCo videolaryngeal mask airway combined with a bronchial blocker in minimally invasive thoracoscopic surgery, compared to tracheal tube placement, can effectively reduce the requirement for vasoactive drugs, improve ventilation outcomes, stabilize hemodynamics, accelerate postoperative awakening, reduce the incidence of postoperative complications, and enhance the quality of postoperative awakening. These findings highlight the potential of this approach as a valuable reference for clinical practice.
|
AJTR Copyright © 2024.
|
10.62347/WNAG4919
|
Compared to the E group, the L group exhibited significantly higher HR and MAP at time points P2, P3, and P4 (P < 0.05). The L group also demonstrated lower Ppeak and Pplat levels from T1 to T4 compared to the E group (P < 0.05). There was no significant difference in SpO
|
[
"Minimally invasive thoracoscopic surgery",
"SaCo videolaryngeal mask airway",
"bronchial blocker",
"complications",
"medication usage",
"quality of recovery"
] |
2025-01-17
|
To investigate the efficacy of the SaCo videolaryngeal mask airway (VLMA) in combination with a bronchial blocker in patients undergoing minimally invasive thoracoscopic surgery.
A retrospective analysis was conducted on the clinical data of 120 patients who underwent minimally invasive thoracoscopic surgery from January 2022 to December 2023. Patients were grouped based on their treatment methods: 68 patients who received the SaCo VLMA combined with a bronchial blocker intraoperatively were designated as the L group, while 52 patients who received a tracheal tube combined with a bronchial blocker intraoperatively were designated as the E group. Heart rate (HR) and mean arterial pressure (MAP) were compared between the two groups at several time points: prior to anesthesia induction (P1), immediately after anesthesia induction (P2), 1 minute after the insertion of the tracheal tube or placement of the laryngeal mask airway (P3), and 1 minute after the removal of the tracheal tube or laryngeal mask airway (P4). Additionally, the following parameters were recorded and compared: peak airway pressure (Ppeak), airway plateau pressure (Pplat), and pulse oxygen saturation (SpO
Compared to the E group, the L group exhibited significantly higher HR and MAP at time points P2, P3, and P4 (P < 0.05). The L group also demonstrated lower Ppeak and Pplat levels from T1 to T4 compared to the E group (P < 0.05). There was no significant difference in SpO
The use of the SaCo videolaryngeal mask airway combined with a bronchial blocker in minimally invasive thoracoscopic surgery, compared to tracheal tube placement, can effectively reduce the requirement for vasoactive drugs, improve ventilation outcomes, stabilize hemodynamics, accelerate postoperative awakening, reduce the incidence of postoperative complications, and enhance the quality of postoperative awakening. These findings highlight the potential of this approach as a valuable reference for clinical practice.
|
[
{
"affiliation": "Department of Anesthesiology, Xidian Group Hospital Xi'an 710077, Shaanxi, China.",
"collective": null,
"firstname": "Yang",
"initials": "Y",
"lastname": "Chen"
},
{
"affiliation": "Department of Anesthesiology, Xidian Group Hospital Xi'an 710077, Shaanxi, China.",
"collective": null,
"firstname": "Na",
"initials": "N",
"lastname": "Ji"
}
] |
American journal of translational research
| null |
39822546
36479830
32660923
33857201
36684172
29078661
24557112
31898776
36511494
35799554
37793330
11967593
29707376
21168744
22165351
26957697
32311952
32913210
32311952
36138363
|
Application value of using a SaCo videolaryngeal mask airway combined with a bronchial blocker in patients undergoing minimally invasive thoracoscopic surgery.
| null | null | null | null | null | null |
null |
Copyright: © 2024 The PLOS Neglected Tropical Diseases Editors. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
|
10.1371/journal.pntd.0012563
10.1371/journal.pntd.0005397
10.1371/journal.pntd.0010975
10.1099/00207713-45-3-589
| null |
[] |
2024-10-07
|
[This corrects the article DOI: 10.1371/journal.pntd.0005397.].
|
[
{
"affiliation": null,
"collective": null,
"firstname": null,
"initials": null,
"lastname": null
}
] |
PLoS neglected tropical diseases
| null |
39374189
28241043
36512533
8590688
|
Correction: Use of eschar swabbing for the molecular diagnosis and genotyping of Orientia tsutsugamushi causing scrub typhus in Quang Nam province, Vietnam.
| null | null | null | null | null | null |
null | null |
10.1007/s40429-023-00493-4
10.15585/mmwr.mm6911a4
10.1016/j.drugalcdep.2019.03.004
10.1002/14651858.CD011117.pub2
10.1038/s41380-018-0094-5
10.1186/1741-7015-9-48
10.4103/ijem.IJEM_617_17
10.1016/j.ecl.2013.09.009
10.1186/1471-2296-14-28
10.1056/NEJMoa1614362
10.1080/02640414.2011.553965
10.1037/hea0000106
10.1093/oxfordhb/9780190243470.013.27
10.1038/s41598-020-62556-0
10.1080/08897077.2017.1363122
10.1155/2014/514589
10.1057/s41285-017-0055-0
10.1016/j.drugalcdep.2018.06.014
10.3109/10826084.2013.841246
10.1079/bjn2002702
10.3109/00952990903544851
10.1080/08897077.2016.1179705
10.1016/j.jsat.2014.10.007
10.1016/j.drugalcdep.2022.109575
10.5812/ijhrba.27587
10.1016/j.psychres.2018.12.153
10.1001/archpsyc.63.2.210
10.1080/14656566.2019.1692815
10.1210/jc.2009-1350
10.5055/jom.2011.0048
10.1038/nrcardio.2013.159
10.3389/fphys.2016.00436
10.1038/s41598-021-91533-4
10.1038/s41598-022-13926-3
10.1097/ADM.0b013e318262a9a1
10.5812/ijhrba.22702
10.3109/00952991003734277
10.1186/1476-511x-7-42
10.1055/s-0031-1280017
10.1080/00952990802122580
10.1080/13556210410001674095
10.1007/s43188-019-00019-z
10.5812/ijhrba.14021
10.1111/j.1365-2125.2009.03364.x
10.1172/jci107869
10.1161/01.Hyp.0000200710.29498.80
10.5812/aapm.5139
10.1161/01.hyp.9.6.561
10.1111/j.1476-5381.1972.tb06887.x
10.1007/s11892-022-01473-0
10.1016/0026-0495(83)90065-3
10.1055/s-2007-1011844
10.5055/jom.2010.0043
10.1080/14740338.2019.1646246
10.1080/14659891.2019.1588404
10.1097/ADM.0b013e31826bd76c
10.1007/bf00260963
10.1016/j.drugalcdep.2012.01.013
10.2337/diacare.7.1.92
10.1016/s0306-3623(96)00165-6
10.1097/01.pra.0000351884.83377.e2
10.1111/j.1365-2125.1981.tb01189.x
10.1073/pnas.1400332111
10.1016/j.physbeh.2012.03.009
10.1016/j.euroneuro.2016.06.013
10.1111/obr.12354
10.1001/archneur.64.11.1575
10.1111/adb.12977
10.1177/2167702619855659
10.1007/s00213-019-05349-2
10.1016/j.addbeh.2020.106673
10.1016/j.brainresbull.2015.12.004
10.1111/j.1360-0443.1989.tb00566.x
10.1080/10826080701517727
10.1017/s0007114510003971
10.1038/s41398-021-01559-5
10.1007/s00213-013-3077-x
10.1177/0269881112472567
10.1177/0269881117742116
10.1016/j.drugalcdep.2021.109017
10.1016/s0376-8716(02)00186-2
10.1007/s00213-021-05774-2
10.1038/mp.2012.154
10.1007/s00213-011-2503-1
10.1016/j.jsat.2017.12.008
10.1038/nrgastro.2017.141
10.1038/s41598-018-23717-4
10.1037/adb0000575
10.1186/1471-2458-12-1058
10.1161/01.Atv.0000099786.99623.Ef
10.1210/jc.2003-030214
10.3390/ijerph17093287
10.3109/10826084.2011.635324
10.1093/aje/kwf157
10.1371/journal.pone.0108223
10.1177/0091270003258190
10.1038/s41598-020-75797-w
10.2337/diacare.24.8.1403
10.1016/s0022-3999(02)00429-4
10.1210/en.2004-0037
10.1007/bf03347017
10.1016/s0306-4530(00)00035-4
10.1210/clinem/dgaa499
10.1210/jcem.85.6.6615
10.1016/j.psyneuen.2009.05.013
10.1016/j.psyneuen.2010.12.017
10.1371/journal.pone.0150729
10.1007/s002130000644
10.1080/13556210020040235
10.1016/S0026-0495(00)80077-3
10.1038/emm.2013.53
10.1172/jci21625
10.1007/s11010-007-9625-0
10.1007/s11481-020-09951-6
10.1111/j.1742-7843.2004.950202.x
| null |
[
"Addiction",
"Dependence",
"Heroin",
"Medication",
"Metabolism",
"Nutrition"
] |
2023-11-20
|
Opioid use disorder (OUD) is a chronic, relapsing condition that is epidemic in the USA. OUD is associated with serious adverse consequences, including higher incarceration rates, impaired medical and mental health, and overdose-related fatalities. Several medications with demonstrated clinical efficacy in reducing opioid use are approved to treat OUD. However, there is evidence that medications for OUD cause metabolic impairments, which raises concerns over the long-term metabolic health of individuals recovering from OUD. Here, we summarize the scientific literature on the metabolic effects of the use of opioids, including medications for treating OUD.
Our findings showed lower body weight and adiposity, and better lipid profiles in individuals with OUD. In individuals with diabetes mellitus, opioid use was associated with lower blood glucose levels. In contrast, among individuals without underlying metabolic conditions, opioids promoted insulin resistance. Treatment of OUD patients with the agonists methadone or buprenorphine caused weight gain, increased liking and intake of sugar, and impaired lipid profile and glucose metabolism, whereas treatment with the antagonist naltrexone demonstrated evidence for reduced sweet preferences.
Our findings highlighted a gap in knowledge regarding the safety of medications for OUD. Further research is needed to determine how best to reduce the risk of metabolic disorder in the treatment of OUD with opioid agonists versus antagonists.
|
[
{
"affiliation": "Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St. Suite 500, Philadelphia, PA 191904, USA.",
"collective": null,
"firstname": "Juliana I",
"initials": "JI",
"lastname": "Byanyima"
},
{
"affiliation": "Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St. Suite 500, Philadelphia, PA 191904, USA.",
"collective": null,
"firstname": "Xinyi",
"initials": "X",
"lastname": "Li"
},
{
"affiliation": "Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St. Suite 500, Philadelphia, PA 191904, USA.",
"collective": null,
"firstname": "Sianneh A",
"initials": "SA",
"lastname": "Vesslee"
},
{
"affiliation": "Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St. Suite 500, Philadelphia, PA 191904, USA.",
"collective": null,
"firstname": "Henry R",
"initials": "HR",
"lastname": "Kranzler"
},
{
"affiliation": "Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St. Suite 500, Philadelphia, PA 191904, USA.",
"collective": null,
"firstname": "Zhenhao",
"initials": "Z",
"lastname": "Shi"
},
{
"affiliation": "Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St. Suite 500, Philadelphia, PA 191904, USA.",
"collective": null,
"firstname": "Corinde E",
"initials": "CE",
"lastname": "Wiers"
}
] |
Current addiction reports
| null |
37982033
23820967
32191688
31039486
27157143
29934549
21985817
21542944
30148108
24582089
23442783
28604169
21416445
25133837
32221389
26089926
28771091
24729884
31007613
30077926
24102254
12425731
20141402
27093441
25441923
35868182
27162765
30611963
16461865
31762335
3908352
19846734
21434584
24145895
27790151
34103610
35798768
22895461
26405680
26322211
26885351
20465370
18980684
25679001
24494156
25140211
21800277
18584567
15203439
32685426
24971288
19371311
4612057
16432042
24757596
24223329
28412823
3294591
4655265
35593927
6358781
3319862
21269006
31317815
23013781
7173523
22356890
6368156
9112073
19461397
7306425
24550305
22450260
27397863
26644270
17998440
33098179
32042509
31463541
33022538
26711857
16225073
2720181
17918026
20880416
34453034
23568577
23364815
29207922
34488077
12167557
33527169
23147384
21960180
29415851
29139482
29651005
32202820
23216869
14551151
14557461
32397260
27065765
15717844
22217127
12480655
25310282
14615465
33122744
11473077
12377295
15044359
14594110
11070333
32866966
10852454
19540049
21256679
27010803
11351934
11341855
10693912
23788131
15599400
17934700
32827051
15379780
|
Metabolic profiles associated with opioid use and opioid use disorder: a narrative review of the literature.
| null | null | null | null | null | null |
MPT is highly heterogeneous and risk stratification to optimize the use of therapeutic interventions in unison with palliative interventions is needed to maximize efforts toward improving patient quality of life. There is an alarming need of PC services in the multidisciplinary management of patients within developing regions.
| null |
10.1177/1049909120969963
|
Seventy patients (median 58 years) were included. 58% were synchronously diagnosed with MPT at time of primary tumor diagnosis. Most common oncologic diagnoses were prostate (25.7%), gastrointestinal (20%), and breast (18.6%) neoplasms. Median overall survival (OS) was 1.9 months. Primaries other than prostate, breast, and lung (HR 1.37, 95% CI 1.15 - 1.8; p = 0.02) and transfusion requirements (HR 2.8, 95% CI 1.01 - 7.9; p = 0.04) were independently associated with decreased OS. Administration of multiple systemic therapeutic interventions (HR 0.15, 95% CI 0.06 - 0.39; p = 0.01) was the sole factor improving OS. Assessment by PC was pursued in 51.4% of patients. The median number of consults per patient was two, with no difference in assessment rate or consult number across different primaries (P = 0.96). Four cases of palliative sedation were reported, all performed by the primary care team.
|
[
"bone marrow neoplasms",
"carcinoma",
"leukoerythroblastic anemia",
"low income population",
"myelophthisic anemia",
"neoplasm metastasis",
"palliative care"
] |
2020-11-10
|
Myelophthisis (MPT) has been associated with a dreadful prognosis. Patients' access to palliative care (PC) and factors influencing its clinical outcomes are poorly described. Our aim was to analyze the impact of patient- and disease-specific characteristics on survival of patients with MPT and describe their use of PC in a resource-limited setting.
Retrospective study including patients with solid tumor MPT, diagnosed between 1996 and 2018.
Seventy patients (median 58 years) were included. 58% were synchronously diagnosed with MPT at time of primary tumor diagnosis. Most common oncologic diagnoses were prostate (25.7%), gastrointestinal (20%), and breast (18.6%) neoplasms. Median overall survival (OS) was 1.9 months. Primaries other than prostate, breast, and lung (HR 1.37, 95% CI 1.15 - 1.8; p = 0.02) and transfusion requirements (HR 2.8, 95% CI 1.01 - 7.9; p = 0.04) were independently associated with decreased OS. Administration of multiple systemic therapeutic interventions (HR 0.15, 95% CI 0.06 - 0.39; p = 0.01) was the sole factor improving OS. Assessment by PC was pursued in 51.4% of patients. The median number of consults per patient was two, with no difference in assessment rate or consult number across different primaries (P = 0.96). Four cases of palliative sedation were reported, all performed by the primary care team.
MPT is highly heterogeneous and risk stratification to optimize the use of therapeutic interventions in unison with palliative interventions is needed to maximize efforts toward improving patient quality of life. There is an alarming need of PC services in the multidisciplinary management of patients within developing regions.
|
[
{
"affiliation": "Department of Hematology and Oncology, 42559Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.",
"collective": null,
"firstname": "Cesar",
"initials": "C",
"lastname": "Vargas-Serafin"
},
{
"affiliation": "Department of Hematology and Oncology, 42559Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.",
"collective": null,
"firstname": "Aldo A",
"initials": "AA",
"lastname": "Acosta-Medina"
},
{
"affiliation": "Department of Hematology and Oncology, 42559Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.",
"collective": null,
"firstname": "Kevin",
"initials": "K",
"lastname": "Teran-De-la-Sancha"
},
{
"affiliation": "Department of Pathology, 42559Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.",
"collective": null,
"firstname": "Jesus",
"initials": "J",
"lastname": "Delgado-de-la-Mora"
},
{
"affiliation": "Department of Hematology and Oncology, 42559Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.",
"collective": null,
"firstname": "María T",
"initials": "MT",
"lastname": "Bourlon"
},
{
"affiliation": "Department of Hematology and Oncology, 42559Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.",
"collective": null,
"firstname": "Christianne",
"initials": "C",
"lastname": "Bourlon"
}
] |
The American journal of hospice & palliative care
| null |
33161730
|
Access to Palliative Care Services and Clinical Outcomes of Patients With Solid Malignancy-Associated Myelophthisis in a Resource-Limited Setting.
| null | null | null | null | null | null |
null | null |
10.3390/clinpract11020049
10.1111/j.1742-481X.2012.00942.x
10.1097/01.ASW.0000530069.82749.e5
10.1097/00006842-200103000-00004
10.1111/ddg.12405_suppl
10.1111/j.1742-481X.2012.01089.x
10.1016/j.jval.2017.07.007
10.1111/iwj.12603
10.1136/pgmj.2006.055905
10.1097/00006534-198310000-00032
10.1146/annurev.ento.45.1.55
10.1515/hsz-2013-0263
10.1046/j.1524-475X.2002.10403.x
10.1111/wrr.12127
10.3310/hta13550
10.1111/j.1365-2915.1988.tb00188.x
10.1086/423806
10.12968/jowc.2017.26.12.734
10.1097/BRS.0b013e3181cd3076
10.1177/2156587214555714
10.5935/2177-1235.2014RBCP0099
10.1186/1477-7525-5-44
10.1155/2018/4934890
10.1002/14651858.CD003556.pub2
10.1136/bmj.b773
10.1016/j.ctim.2013.08.016
10.2337/diacare.26.2.446
10.1016/S0965-206X(00)80036-4
| null |
[
"Lucilia sericata",
"debridement",
"holistic care",
"larva",
"maggot therapy",
"multimorbid",
"ulcer",
"wounds"
] |
2021-07-03
|
Patients with chronic wounds (leg ulcers, decubitus, and diabetic foot ulcers) suffer from marked restrictions in their quality of life and can often no longer adequately carry out their everyday tasks. The need for nursing and medical care increases when other illnesses and complaints are present at the same time. Qualified wound care and the treatment of comorbidities are therefore of particular importance. The treatment of this disease, which is increasing in number, requires a holistic, multimodal treatment approach which, in addition to professional wound care, also includes comorbidities in the treatment. This case study describes an old treatment method for refractory wounds, the so-called "maggot therapy", and shows how this is integrated into a holistic, multimodal therapeutic approach.
|
[
{
"affiliation": "Medical Informatics and Technology, Institute for Management and Economics in Health Care, UMIT-University of Health Sciences, 6060 Hall in Tirol, Austria.\nComplementary and Individualized Patient Centred Medicine, Pain Therapy, Acute Hospital for Internal Medicine, Waldhausklinik, 86391 Deuringen, Germany.",
"collective": null,
"firstname": "Tobias",
"initials": "T",
"lastname": "Romeyke"
}
] |
Clinics and practice
| null |
34199361
|
Maggot Therapy as a Part of a Holistic Approach in the Treatment of Multimorbid Patients with Chronic Ulcer.
| null | null | null | null | null | null |
null |
Copyright © 2025 Elsevier Inc. All rights reserved.
|
10.1016/j.taap.2025.117350
| null |
[
"A549 and LLC-1 cell line",
"Apoptosis",
"Neohesperidin",
"Second mitochondria-derived activator of caspase",
"X-linked inhibitor of apoptosis protein"
] |
2025-04-20
|
Lung cancer is a significant contributor to global mortality rates in the human population. However, the results of current treatment options are still unsatisfactory. Thus, the study explores low-toxic natural substances that release caspases and trigger apoptosis. Neohesperidin (NHP), a flavonoid, has anticancer efficacy although its molecular mechanism is unknown. In the current work, through in-silico and in-vitro screening, we discovered that NHP significantly reduces the expression of x-linked inhibitor of apoptosis protein (xIAP) and ATP on its administration, leading to apoptosis in human and mice lung (A549 and LLC-1) cancerous cells. Furthermore, NHP promoted the production of second-mitochondria-derived-activator-of-caspase (SMAC) and triggers mitochondrial dysfunction which also promotes apoptosis (51.1 %) as well as necrosis (25.8 %). This mechanism is regulated by mitochondria-mediated (Bax and Bcl-2) caspases-dependent apoptotic and ROS mediated pathway which increases SMAC expression by 21.2 % along with lowering the xIAP level (by 36.5 %). Moreover, network pharmacology was utilized to delineate the interactions of the compounds within biological networks, emphasizing their potential to target multiple pathways. In addition, we investigated the alterations in metabolites within A549 cells caused by NHP using liquid-chromatography-high-resolution-mass-spectrometry (LC-HRMS)-based metabolomics. The results revealed perturbations in metabolomes that are involved in multiple pathways. Therefore, this study indicates that NHP is a potential therapeutic agent to mitigate and control the proliferation of lung cancer and also regulates the energy metabolism.
|
[
{
"affiliation": "Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.",
"collective": null,
"firstname": "Ruchi",
"initials": "R",
"lastname": "Pandey"
},
{
"affiliation": "Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.",
"collective": null,
"firstname": "Khushboo",
"initials": "K",
"lastname": "Choudhary"
},
{
"affiliation": "Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.",
"collective": null,
"firstname": "Surendra Rajit",
"initials": "SR",
"lastname": "Prasad"
},
{
"affiliation": "Institute of Pharmaceutical Sciences, University of Lucknow, Lucknow, Uttar Pradesh, India.",
"collective": null,
"firstname": "Pranesh",
"initials": "P",
"lastname": "Kumar"
},
{
"affiliation": "Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.",
"collective": null,
"firstname": "Priya",
"initials": "P",
"lastname": "Bisht"
},
{
"affiliation": "Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.",
"collective": null,
"firstname": "Dande",
"initials": "D",
"lastname": "Aishwarya"
},
{
"affiliation": "Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.",
"collective": null,
"firstname": "Pallaprolu",
"initials": "P",
"lastname": "Nikhil"
},
{
"affiliation": "Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, , Manipal, India.",
"collective": null,
"firstname": "Sachindra",
"initials": "S",
"lastname": "Kumar"
},
{
"affiliation": "Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India.",
"collective": null,
"firstname": "Ramalingam",
"initials": "R",
"lastname": "Peraman"
},
{
"affiliation": "Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, Hajipur, Bihar, India. Electronic address: [email protected].",
"collective": null,
"firstname": "Nitesh",
"initials": "N",
"lastname": "Kumar"
}
] |
Toxicology and applied pharmacology
| null |
40252982
|
Mechanistic and metabolic exploration of neohesperidin against lung cancer cell lines through ROS-mediated mitochondrial apoptosis: An in-silico and in-vitro approach.
| null | null | null | null | null | null |
null |
© 2024 The Authors.
|
10.1016/j.radcr.2024.08.052
10.1016/j.radcr.2022.05.081
10.1155/2020/9496564
10.1016/j.rmr.2019.07.010
10.1164/rccm.201710-1967CI
10.1016/j.reval.2012.01.009
10.5603/ARM.2020.0088
10.4168/aair.2010.2.2.144
10.1183/09031936.00221811
| null |
[
"AEP",
"Acute eosinophilic pneumonia",
"Cannabis",
"Case report",
"Eosinohilic lung disease"
] |
2024-09-23
|
This article explores the case of acute eosinophilic pneumonia (AEP) linked to heavy cannabis inhalation, amidst the rising prevalence of cannabis use globally. AEP, characterized by eosinophilic pulmonary infiltration, poses unique challenges due to its unclear pathogenesis. This case study involves a 20-year-old with recent intense cannabis use, presenting with acute chest pain, cough, and dyspnea. Diagnostic evaluation revealed bilateral interstitial syndrome on thoracic imaging and elevated blood eosinophilia. Additional investigation through bronchoalveolar lavage confirmed the diagnosis of AEP. The patient's condition rapidly improved with glucocorticoids, highlighting the significance of prompt treatment. This article underscores the importance of raising awareness among clinicians of the possibility of AEP following cannabis exposure as a diagnosis to consider, as timely diagnosis and intervention are paramount in averting potentially fatal outcomes.
|
[
{
"affiliation": "Pulmonology Department, Centre Hospitalier Universitaire Ibn Sina, Rabat, Morocco.\nPulmonology Department, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France.",
"collective": null,
"firstname": "Bouchra",
"initials": "B",
"lastname": "Badri"
},
{
"affiliation": "Pulmonology Department, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France.",
"collective": null,
"firstname": "François",
"initials": "F",
"lastname": "Bildstein"
},
{
"affiliation": "Pulmonology Department, Centre Hospitalier Sud Francilien, Corbeil-Essonnes, France.",
"collective": null,
"firstname": "Philippe",
"initials": "P",
"lastname": "Menager"
}
] |
Radiology case reports
| null |
39308620
35769119
32047695
31862136
29206477
12403693
30188028
32383466
20358030
22599359
|
A rare discovery of acute eosinophilic pneumonia associated with intensive cannabis use: Case report.
| null | null | null | null | null | null |
null | null |
10.1097/01.ju.0000101000.08371.79
|
Renal reconstruction with fibrin sealant resulted in significantly lower blood loss (62 vs 155 ml, p <0.05) and time to hemostasis (3.5 vs 6.5 minutes, p <0.05) than in the conventional suture groups. There was no radiographic or gross evidence of significant postoperative bleeding, urinoma formation or abnormal tissue healing in the recovery period. Gelatin sponge and collagen sheet demonstrated similar hemostatic efficacy.
|
[] |
2003-12-11
|
We determined whether fibrin sealant augmented by an absorbable bolster could salvage kidneys with major, centrally located stab wounds.
A grade 4 renal injury was created in 16 commercial swine via a 1.5 cm sagittal, centrally located, through-and-through right renal laceration. Animals were randomized to 1 of 4 treatment arms, including control groups that received conventional renal capsule suture repair with an absorbable gelatin sponge bolster (3 in group 1) or a microfibrillar collagen sheet (3 in group 2) and experimental groups that received sutureless treatment entailing fibrin sealant instillation into the knife tract augmented by an external gelatin sponge (5 in group 3) or an external microfibrillar collagen sheet (5 in group 4). Arterial occlusion was not performed. Blood loss and time to hemostasis were recorded. Abdominal computerized tomography was performed at 1 week and necropsy was done at 6 weeks.
Renal reconstruction with fibrin sealant resulted in significantly lower blood loss (62 vs 155 ml, p <0.05) and time to hemostasis (3.5 vs 6.5 minutes, p <0.05) than in the conventional suture groups. There was no radiographic or gross evidence of significant postoperative bleeding, urinoma formation or abnormal tissue healing in the recovery period. Gelatin sponge and collagen sheet demonstrated similar hemostatic efficacy.
In this porcine renal trauma model fibrin sealant augmented by absorbable gelatin sponge or a microfibrillar collagen sheet effectively promoted hemostasis and renal salvage. Because of its safety, ease of use and efficiency, fibrin sealant appears to be an appropriate adjunct for managing challenging renal injuries.
|
[
{
"affiliation": "Urology Service, Brooke Army Medical Center, Fort Sam Houston, San Antonio, Texas, 78234, USA.",
"collective": null,
"firstname": "Brian C",
"initials": "BC",
"lastname": "Griffith"
},
{
"affiliation": null,
"collective": null,
"firstname": "Allen F",
"initials": "AF",
"lastname": "Morey"
},
{
"affiliation": null,
"collective": null,
"firstname": "Thomas A",
"initials": "TA",
"lastname": "Rozanski"
},
{
"affiliation": null,
"collective": null,
"firstname": "Richard",
"initials": "R",
"lastname": "Harris"
},
{
"affiliation": null,
"collective": null,
"firstname": "Scott R",
"initials": "SR",
"lastname": "Dalton"
},
{
"affiliation": null,
"collective": null,
"firstname": "Sigurd J",
"initials": "SJ",
"lastname": "Torgerson"
},
{
"affiliation": null,
"collective": null,
"firstname": "Scott R",
"initials": "SR",
"lastname": "Partyka"
}
] |
The Journal of urology
| null |
14665952
|
Central renal stab wounds: treatment with augmented fibrin sealant in a porcine model.
| null | null | null | null | null | null |
null |
Copyright © 2023 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.
|
10.1016/j.jaapos.2022.12.003
| null |
[] |
2023-02-06
|
Inverse globe retraction syndrome is a rare ocular motility disorder characterized by limited abduction, with globe retraction and up- or downshoots on attempted abduction, differentiating it from globe retraction due to Duane retraction syndrome, seen on attempted adduction. It can be congenital or acquired. We report the case of a 3-year-old girl who presented with classical features of inverse globe retraction syndrome secondary to an underlying orbital tumor involving the medial rectus muscle. Incisional biopsy confirmed the diagnosis of a leiomyoma. At 10 months' follow-up, vision, ocular alignment, and ocular motility had improved.
|
[
{
"affiliation": "Pediatric Ophthalmology and Strabismus Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.",
"collective": null,
"firstname": "Gayathri J",
"initials": "GJ",
"lastname": "Panicker"
},
{
"affiliation": "Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.",
"collective": null,
"firstname": "Preeta",
"initials": "P",
"lastname": "Nair A K"
},
{
"affiliation": "Pediatric Ophthalmology and Strabismus Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India. Electronic address: [email protected].",
"collective": null,
"firstname": "Sumita",
"initials": "S",
"lastname": "Agarkar"
},
{
"affiliation": "Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.",
"collective": null,
"firstname": "Sonam Poonam",
"initials": "SP",
"lastname": "Nisar"
},
{
"affiliation": "Department of Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.",
"collective": null,
"firstname": "Leena Dennis",
"initials": "LD",
"lastname": "Joseph"
}
] |
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
| null |
36739941
|
Orbital leiomyoma presenting as inverse globe retraction syndrome: a unique presentation of a rare disease.
| null | null | null | null | null | null |
null | null |
10.3760/cma.j.cn112144-20241223-00503
| null |
[] |
2025-03-28
|
Effective management of postoperative pain following oral surgery is crucial for enhancing patient care quality. Given the high sensitivity of the oral region and its complex neural network, managing postoperative pain poses significant clinical challenges. This review assessed the efficacy of pharmacological treatments methods (such as non-steroidal anti-inflammatory drugs, acetaminophen and corticosteroids) and non-pharmacological treatment strategies (such as physical therapy, cognitive behavioral therapy, and psychological support), and discussed how these methods can be synergistically optimized for pain management. Additionally, this paper explored the challenges associated with implementing these strategies, including the standardization of pain assessment, the ongoing education of nursing staff, and the importance of interdisciplinary team collaboration. By integrating these approaches, this review aims to guide improvements in clinical pain management practices to enhance patient recovery outcomes and satisfaction, reduce reliance on pharmacological treatments, and ultimately elevate the overall quality of nursing care.
有效的口腔外科术后疼痛管理对提升患者护理质量至关重要。口腔区域的高敏感性和复杂的神经网络，对口腔外科术后疼痛的管理提出了显著的临床挑战。本综述评估了药物治疗方法（如非甾体抗炎药、对乙酰氨基酚和糖皮质激素）以及非药物治疗策略（如物理治疗、认知行为疗法和心理支持）的应用效果，并探讨这些方法如何共同优化疼痛管理。此外，本文还探讨了执行这些策略的挑战，包括疼痛评估的标准化、护理人员的持续教育和跨专业团队协作的重要性。通过综合这些方法，本综述旨在指导临床实践中的疼痛管理改进，以增强患者的康复效果和满意度，同时减少对药物治疗的依赖，进而提高护理服务的整体质量。.
|
[
{
"affiliation": "Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University & State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Chengdu 610044, China.",
"collective": null,
"firstname": "C L",
"initials": "CL",
"lastname": "Liu"
},
{
"affiliation": "Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University & State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Chengdu 610044, China.",
"collective": null,
"firstname": "L W",
"initials": "LW",
"lastname": "Hu"
},
{
"affiliation": "Department of Oral Surgery, West China Hospital of Stomatology, Sichuan University & State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases, Chengdu 610044, China.",
"collective": null,
"firstname": "X F",
"initials": "XF",
"lastname": "Tan"
}
] |
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
| null |
40147905
|
[Nursing strategies and challenges in managing postoperative pain in oral surgery].
| null | null | null | null | null | null |
Managing anesthesia for renal tumors with IVC invasion requires careful preoperative planning, invasive monitoring, and multidisciplinary approach.
|
© 2025 The Author(s). Published by S. Karger AG, Basel.
|
10.1159/000542962
| null |
[
"Anesthesia",
"Hemodynamic monitoring",
"Inferior vena cava",
"Kidney cancer",
"Multidisciplinary care"
] |
2025-02-21
|
Renal tumors with inferior vena cava (IVC) invasion pose significant challenges for surgical and anesthetic management. This report presents the anesthetic management of a patient with a level 3 IVC-invading renal tumor, emphasizing the complexity and multidisciplinary approach required.
A 55-year-old woman with a large left renal tumor causing complete obstruction of the left renal vein and near-total obstruction of the IVC was admitted for surgery. Multidisciplinary planning included a nephrectomy with removal of tumor from the IVC. The patient underwent general anesthesia with extensive hemodynamic monitoring and fluid management to mitigate potential blood loss and cardiovascular instability. The surgery, lasting 5 h, involved successful radical nephrectomy, tumor removal from the IVC, and resection of liver metastases. Postoperative recovery was without complications, and the patient was discharged 7 days.
Managing anesthesia for renal tumors with IVC invasion requires careful preoperative planning, invasive monitoring, and multidisciplinary approach.
|
[
{
"affiliation": "Department of Anesthesiology, University Medical Center HCMC, Ho Chi Minh City, Vietnam.",
"collective": null,
"firstname": "Vu Ton Ngoc",
"initials": "VTN",
"lastname": "Phan"
},
{
"affiliation": "Department of Anesthesiology, University Medical Center HCMC, Ho Chi Minh City, Vietnam.",
"collective": null,
"firstname": "Phat Thanh",
"initials": "PT",
"lastname": "Tran"
},
{
"affiliation": "Department of Anesthesiology, University Medical Center HCMC, Ho Chi Minh City, Vietnam.\nDepartment of Anesthesiology, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.",
"collective": null,
"firstname": "Dao Thi Ngoc",
"initials": "DTN",
"lastname": "Nguyen"
}
] |
Case reports in oncology
| null |
39980515
12576811
19560258
28411712
20883481
12352396
35950044
37641726
38562176
20103332
37568007
11517137
33459041
32809720
32082813
|
Anesthetic Management of Renal Tumor with Level 3 Inferior Vena Cava Extension at a University Hospital in Vietnam: A Case Report.
| null | null | null | null | null | null |
null | null |
10.22551/2021.32.0803.10187
10.4081/oncol.2014.259
10.21873/invivo.11128
10.1309/AJCP5NK0FJCGHTFM
10.1053/j.semdp.2012.01.003
10.1016/j.rmcr.2017.05.005
10.1097/PAS.0000000000000511
10.1016/j.humpath.2017.08.035
10.2214/ajr.161.4.8372760
10.1016/j.ijsu.2006.06.009
| null |
[
"Actinomyces meyeri",
"angiomyomatous hamartoma",
"epithelioid hemangioendothelioma",
"wound infection"
] |
2022-01-06
|
Epithelioid hemangioendothelioma is a rare vascular malignancy that originates from vascular endothelial or pre-endothelial cells and is composed of epithelioid or histiocytoid cells. This malignancy has an incidence of approximately one per one million individuals and can occur in various regions of the body including the lungs, liver, bones, and soft tissues. The behavior of this cancer can range from indolent to aggressive and diagnosis and treatment are often delayed due to variable presentations and lack of established treatment guidelines. Here we present the case of a 27-year-old Hispanic male that presented with right groin pain, abdominal pain, and a fifty-pound weight loss over one year. The patient had a complex hospital course during which he was found to have an angiomyomatous hamartoma of his right groin area, postsurgical right inguinal wound infection with Actinomyces meyeri, and epithelioid hemangioendothelioma distal to the right iliac bifurcation. The patient is currently pending further imaging studies to evaluate candidacy for surgical resection and following with oncology for chemotherapeutic options.
|
[
{
"affiliation": "Department of Internal Medicine, University of Texas Health Science Center San Antonio, TX, USA.",
"collective": null,
"firstname": "Nariman",
"initials": "N",
"lastname": "Khan"
},
{
"affiliation": "Department of Internal Medicine, University of Texas Health Science Center San Antonio, TX, USA.",
"collective": null,
"firstname": "Saadia",
"initials": "S",
"lastname": "Waheed"
},
{
"affiliation": "Department of Pathology and Laboratory Medicine, University of Texas Health Science Center San Antonio, TX, USA.",
"collective": null,
"firstname": "Rahaf",
"initials": "R",
"lastname": "Alkhateb"
}
] |
Archive of clinical cases
| null |
34984227
|
Triple whammy: a rare case of epithelioid hemangioendothelioma with synchronous angiomyomatous hamartoma complicated by Actinomyces meyeri.
| null | null | null | null | null | null |
null |
© 2021 Royal College of Speech and Language Therapists.
|
10.1111/1460-6984.12655
|
Responses were received from 47 SLTs. The majority (40.4%) spent between 1% and 9% of their clinical time with ventilated patients. Almost 80% work with seniors (≥65 years) and almost 70% work with adults (18-65 years) half the time or more. In inpatient rehabilitation, 46.8% reported that they manage patients with tracheostomy half the time or more. In outpatient rehabilitation settings, 21.3% reported that they manage patients with tracheostomy half the time or more. Prior to managing complex airway patients independently, 55.3% received less than 5 h formal tracheostomy training whilst 68.1% received less than 5 h training on ventilated patients. Multidisciplinary teams (MDTs) existed for tracheostomy patients (85.1%) and ventilated patients (70.2%) and high levels of confidence were reported for managing patients with tracheostomies (mode of 4 in a scale of 0-5, where 5 means fully confident) and ventilated patients (mode of 3 in a scale of 0-5). A significant relationship was found between level of confidence and presence of an MDT.
|
[
"critical care",
"long-term care",
"mechanical ventilation",
"speech and language therapy",
"survey",
"tracheostomy"
] |
2021-08-07
|
There is increased involvement of speech and language therapists (SLTs) in critical care and long-term units supporting patients with ventilatory needs and complex dysphagia. SLTs have a range of specialist knowledge in the function of the pharynx and larynx to enable them to support therapeutic interventions and contribute to the management of those patients. In Israel, there are currently no designated courses or training programmes for SLTs to establish advanced clinical skills in tracheostomy and ventilator management. There are currently standards of care for SLT working in designated wards for ventilated patients, however not in acute wards, critical care, and internal medicine wards where ventilated patients can be hospitalized.
To identify the skills and expertise of the Israeli SLT workforce working with tracheostomy patients. Specifically, to identify their level of training, access to training, client population, work settings, and level of work confidence.
The study involved electronic distribution of a 55-item online survey to SLTs in Israel. The questions included demographic information, training, confidence, and clinical support.
Responses were received from 47 SLTs. The majority (40.4%) spent between 1% and 9% of their clinical time with ventilated patients. Almost 80% work with seniors (≥65 years) and almost 70% work with adults (18-65 years) half the time or more. In inpatient rehabilitation, 46.8% reported that they manage patients with tracheostomy half the time or more. In outpatient rehabilitation settings, 21.3% reported that they manage patients with tracheostomy half the time or more. Prior to managing complex airway patients independently, 55.3% received less than 5 h formal tracheostomy training whilst 68.1% received less than 5 h training on ventilated patients. Multidisciplinary teams (MDTs) existed for tracheostomy patients (85.1%) and ventilated patients (70.2%) and high levels of confidence were reported for managing patients with tracheostomies (mode of 4 in a scale of 0-5, where 5 means fully confident) and ventilated patients (mode of 3 in a scale of 0-5). A significant relationship was found between level of confidence and presence of an MDT.
Limited training access was found for SLTs working with this complex population. A competency framework needs to be established with access to training and supervision. MDT existence contributes to confidence. Most respondents worked in rehabilitation settings, and very few worked in acute care, critical care, and internal medicine wards. It seems reasonable that in order to change this, minimal standards of care should be established on these wards.
What is already known on the subject Speech and language therapists (SLTs) have an important role in critical care and long-term units supporting patients with complex dysphagia and undergo formal training and supervision in UK and Australia. What this paper adds to existing knowledge In Israel, most SLTs work with tracheostomy and ventilated adult patients in rehabilitation settings, whilst few work in acute, critical care, and internal medicine wards. There are limited opportunities for formal training and supervision, although MDT support enhances clinical confidence. What are the potential or actual clinical implications of this work? SLTs in Israel would benefit from establishing a competency framework for tracheostomy and ventilator patient management to support training, standards of care, and increase clinical involvement in acute settings. This will enhance clinical outcomes for their large population of complex airway patients.
|
[
{
"affiliation": "Department of Communication Sciences and Disorders, University of Haifa, Haifa, Israel.\nSpeech and Language Department, Reuth Rehabilitation Hospital, Tel Aviv, Israel.",
"collective": null,
"firstname": "Oshrat",
"initials": "O",
"lastname": "Sella Weiss"
},
{
"affiliation": "Speech and Language Department, Reuth Rehabilitation Hospital, Tel Aviv, Israel.\nDepartment of Communication Sciences and Disorders, Ono Academic College, Kiryat Ono, Israel.",
"collective": null,
"firstname": "Aviah",
"initials": "A",
"lastname": "Gvion"
},
{
"affiliation": "Center for Allied Health, St George's University of London, United Kingdom of Great Britain and Northern Ireland, London, UK.\nSpeech and Language Therapy Department, University College London Hospitals, NHS Foundation Trust.",
"collective": null,
"firstname": "Jackie",
"initials": "J",
"lastname": "Mcrae"
}
] |
International journal of language & communication disorders
| null |
34357667
|
Speech and language therapists' management of ventilated patients and patients with tracheostomy in Israel.
| null | null | null | null | null | null |
null | null |
10.1007/978-1-4684-5676-9_40
| null |
[] |
1989-01-01
| null |
[
{
"affiliation": "Institute of Rheumatology, University of Siena, Italy.",
"collective": null,
"firstname": "A",
"initials": "A",
"lastname": "Taddeo"
},
{
"affiliation": null,
"collective": null,
"firstname": "L D",
"initials": "LD",
"lastname": "Fairbanks"
},
{
"affiliation": null,
"collective": null,
"firstname": "H A",
"initials": "HA",
"lastname": "Simmonds"
},
{
"affiliation": null,
"collective": null,
"firstname": "J A",
"initials": "JA",
"lastname": "Duley"
},
{
"affiliation": null,
"collective": null,
"firstname": "G S",
"initials": "GS",
"lastname": "Morris"
}
] |
Advances in experimental medicine and biology
| null |
2514590
|
Deoxy GTP accumulates in thymocytes, but not in T or B lymphocytes in simulated PNP deficiency.
| null | null | null | null | null | null |
null | null |
10.1054/mehy.2000.1051
| null |
[] |
2000-09-14
|
Multiple sclerosis (MS) has a much higher incidence among caucasians that in any other race. Furthermore: females are much more susceptible than males and white females living in colder, wetter areas are much more susceptible than those living in warmer areas. On the other hand, menstruating women have increased copper (Cu) absorption and half-life, so they tend to accumulate more Cu than males. Moreover, rapidly growing girls have an increased demand for zinc (Zn), but their rapidly decreasing production of melatonin results in impaired Zn absorption, which is exacerbated by the high Cu levels. The low Zn levels result in deficient CuZnSuperoxide dismutase (CuZnSOD), which in turn leads to increased levels of superoxide. Menstruating females also often present with low magnesium (Mg) and vitamin B6 levels. Vitamin B6 moderates intracellular nitric oxide (NO) production and extracellular Mg is required for NO release from the cell, so that a deficiency of these nutrients results in increased NO production in the cell and reduced release from the cell. The trapped NO combines with superoxide to form peroxinitrite, an extremely powerful free radical that leads to the myelin damage of MS. Iron (Fe), molybdenum (Mo) and cadmium (Cd) accumulation also increase superoxide production. Which explains MS in males, who tend to accumulate Fe much faster and Cu much less rapidly than females. Since vitamin D is paramount for Mg absorption, the much reduced exposure to sunlight in the higher latitudes may account for the higher incidence in these areas. Moreover, vitamin B2 is a cofactor for xanthine oxidase, and its deficiency exacerbates the low levels of uric acid caused by high Cu levels, resulting in myelin degeneration. Finally Selenium (Se) and vitamin E prevent lipid peroxidation and EPA and DHA upregulate CuZnSOD. Therefore, supplementation with 100 mg MG, 25 mg vit B6, 10 mg vit B2, 15 mg Zn and 400 IU vit D and E, 100 microg Se, 180 mg EPA and 120 mg DHA per day between 14 and 16 years of age may prevent MS.
|
[
{
"affiliation": null,
"collective": null,
"firstname": "S",
"initials": "S",
"lastname": "Johnson"
}
] |
Medical hypotheses
| null |
10985916
|
The possible role of gradual accumulation of copper, cadmium, lead and iron and gradual depletion of zinc, magnesium, selenium, vitamins B2, B6, D, and E and essential fatty acids in multiple sclerosis.
| null | null | null | null | null | null |
null | null |
10.4103/1673-5374.353501
| null |
[
"alpha",
"ambulatory behavior",
"clonidine",
"cortical injury",
"efaroxan",
"functional recovery",
"immunohistochemistry",
"motor deficit",
"norepinephrine",
"sensorimotor score"
] |
2022-10-08
|
Norepinephrine plays an important role in motor functional recovery after a brain injury caused by ferrous chloride. Inhibition of norepinephrine release by clonidine is correlated with motor deficits after motor cortex injury. The aim of this study was to analyze the role of α
|
[
{
"affiliation": "Department of Pharmacology, Section of Postgraduate Studies and Research, High Medical School, Instituto Politécnico Nacional, Salvador Díaz Mirón, Alcaldía Miguel Hidalgo, Mexico City, Mexico.",
"collective": null,
"firstname": "Gabriela",
"initials": "G",
"lastname": "García-Díaz"
},
{
"affiliation": "Department of Neurobiology of Aging and Brain Damage, Coordination of Psychobiology and Neurosciences, Faculty of Psychology, National Autonomous University of Mexico, Av. Universidad 3040, Col. Copilco Universidad, Alcaldía Coyoacán, Mexico City, Mexico.",
"collective": null,
"firstname": "Laura E",
"initials": "LE",
"lastname": "Ramos-Languren"
},
{
"affiliation": "Direction of Research, National Institute of Rehabilitation LGII, Calz. Mexico-Xochimilco 289, Col. Arenal de Guadalupe, Alcaldía Tlalpan, Mexico City, Mexico.",
"collective": null,
"firstname": "Carmen",
"initials": "C",
"lastname": "Parra-Cid"
},
{
"affiliation": "Department of Pharmacology, Section of Postgraduate Studies and Research, High Medical School, Instituto Politécnico Nacional, Salvador Díaz Mirón, Alcaldía Miguel Hidalgo, Mexico City, Mexico.",
"collective": null,
"firstname": "Joel",
"initials": "J",
"lastname": "Lomelí"
},
{
"affiliation": "Department of Pharmacology, Multidisciplinary Academic Unit Reynosa-Aztlan Reynosa, Autonomous University of Tamaulipas, calle 16 y lago de Chapala, Col. Aztlán, Tamaulipas, Mexico.",
"collective": null,
"firstname": "Sergio",
"initials": "S",
"lastname": "Montes"
},
{
"affiliation": "Department of Neurochemistry, National Institute of Neurology and Neurosurgery MVS, Av. Insurgentes Sur 3877, Col. La Fama, Alcaldia Tlalpan, Mexico City, Mexico.",
"collective": null,
"firstname": "Camilo",
"initials": "C",
"lastname": "Ríos"
},
{
"affiliation": "Direction of Research, National Institute of Rehabilitation LGII, Calz. Mexico-Xochimilco 289, Col. Arenal de Guadalupe, Alcaldía Tlalpan, Mexico City, Mexico.",
"collective": null,
"firstname": "Antonio",
"initials": "A",
"lastname": "Bueno-Nava"
},
{
"affiliation": "Department of Pharmacology, Section of Postgraduate Studies and Research, High Medical School, Instituto Politécnico Nacional, Salvador Díaz Mirón, Alcaldía Miguel Hidalgo, Mexico City, Mexico.",
"collective": null,
"firstname": "Ignacio",
"initials": "I",
"lastname": "Valencia-Hernández"
},
{
"affiliation": "Department of Pharmacology, Section of Postgraduate Studies and Research, High Medical School, Instituto Politécnico Nacional, Salvador Díaz Mirón, Alcaldía Miguel Hidalgo; Department of Special Education, University of the Americas, Puebla 223, Col. Roma, Alcaldía Cuauhtémoc, Mexico City, Mexico.",
"collective": null,
"firstname": "Rigoberto",
"initials": "R",
"lastname": "González-Piña"
}
] |
Neural regeneration research
| null |
36204857
32461978
31150628
29733063
28792913
16254995
26639424
23516064
28687925
12668290
18662743
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11284550
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29124985
6690325
0
32999279
19553458
31942516
|
Alpha
| null | null | null | null | null | null |
null | null | null |
Anatomical regeneration of bladder wall primary afferents was demonstrated by the presence of labeled wheat germ agglutinin-horseradish peroxidase fibers in the dorsal horn and sacral parasympathetic nucleus in 8 of 9 cases of olfactory ensheathing cell implantation but not in the 9 controls injected with vehicle. One week after surgery all rats had an atonic bladder on cystometrography. At 6 weeks 8 of the 9 olfactory ensheathing cell implanted rats had recovered bladder activity. No recovery was observed in controls, in which vehicle was injected instead of olfactory ensheathing cells.
|
[] |
2002-02-08
|
We performed spinal implantation of olfactory ensheathing cells to demonstrate dorsal root afferent regeneration as well as bladder activity restoration after lumbosacral L6 to S2 rhizotomy.
Spinal segments receiving bladder innervation, usually L6, S1 and S2, were identified by bipolar stimulation of the ventral roots. Bilateral section of the identified dorsal roots L6 to S2 was performed in 18 male Wistar rats. Immediately after rhizotomy olfactory ensheathing cells or vehicle was unilaterally injected in the vicinity of the sacral parasympathetic nucleus in 9 rats each using a glass micropipette and air pulse system. The severed roots were reattached to the cord with fibrin glue and the animals recovered under antibiotic prophylaxis.
Anatomical regeneration of bladder wall primary afferents was demonstrated by the presence of labeled wheat germ agglutinin-horseradish peroxidase fibers in the dorsal horn and sacral parasympathetic nucleus in 8 of 9 cases of olfactory ensheathing cell implantation but not in the 9 controls injected with vehicle. One week after surgery all rats had an atonic bladder on cystometrography. At 6 weeks 8 of the 9 olfactory ensheathing cell implanted rats had recovered bladder activity. No recovery was observed in controls, in which vehicle was injected instead of olfactory ensheathing cells.
Regenerated primary afferent fibers from the bladder project to the sacral parasympathetic nucleus, where they presumably form synapses mediating the recovery of bladder activity. Thus, olfactory ensheathing cell implants in the adult rat promote sensory axon regeneration, target reinnervation and bladder activity restoration.
|
[
{
"affiliation": "Department of Urology and Neuromorphology Laboratory, Biomedical Research Unit, Hospital of Navarra, Pamplona, Spain.",
"collective": null,
"firstname": "J I",
"initials": "JI",
"lastname": "Pascual"
},
{
"affiliation": null,
"collective": null,
"firstname": "G",
"initials": "G",
"lastname": "Gudiño-Cabrera"
},
{
"affiliation": null,
"collective": null,
"firstname": "R",
"initials": "R",
"lastname": "Insausti"
},
{
"affiliation": null,
"collective": null,
"firstname": "M",
"initials": "M",
"lastname": "Nieto-Sampedro"
}
] |
The Journal of urology
| null |
11832781
|
Spinal implants of olfactory ensheathing cells promote axon regeneration and bladder activity after bilateral lumbosacral dorsal rhizotomy in the adult rat.
| null | null | null | null | null | null |
null | null |
10.3390/plants14030461
10.1146/annurev.arplant.50.1.665
10.1093/pcp/pcab011
10.1046/j.1469-8137.2003.00695.x
10.1093/mp/ssp120
10.1104/pp.111.175281
10.3390/ijms21175955
10.1126/science.aay4970
10.1080/00380768.2024.2408307
10.1023/A:1022332320384
10.1016/j.plantsci.2018.03.013
10.1016/j.plantsci.2010.04.005
10.1007/s00299-021-02773-7
10.18388/abp.2003_3648
10.1016/j.ccr.2012.03.020
10.1074/jbc.M204183200
10.1034/j.1399-3054.2003.00132.x
10.1104/pp.110.154138
10.1016/S0378-1119(03)00764-9
10.1111/j.1469-8137.2007.02356.x
10.3389/fpls.2020.618716
10.1016/j.febslet.2014.08.019
10.1007/s11103-015-0323-0
10.1111/j.1438-8677.2010.00346.x
10.1093/aob/mcr246
10.1038/s41598-017-11490-9
10.1016/j.ijbiomac.2018.11.027
10.3390/ijms20081954
10.1007/s00709-024-01983-6
10.1111/jipb.12184
10.1104/pp.111.183723
10.1093/jxb/eru377
10.1104/pp.110.153270
10.1093/jxb/erab409
10.1104/pp.109.143180
10.1111/pbi.12699
10.1007/s11104-024-06702-x
10.1093/jxb/eraa179
10.1126/science.1253435
10.1016/j.fcr.2022.108614
10.7717/peerj.4822
10.1016/j.plaphy.2024.108389
10.1007/s00122-008-0836-x
10.1371/journal.pgen.1001102
10.1093/plphys/kiac521
10.1111/nph.16931
10.1104/pp.104.041442
10.1038/nrg2689
10.1038/nrg.2017.26
10.3389/fpls.2017.00035
10.3390/ijms21103660
10.3727/000000001783992731
10.1007/s11103-015-0289-y
10.3389/fpls.2019.00246
10.1093/nar/gkab1057
10.1093/nar/gkaa913
10.1093/nar/28.1.231
10.1093/bioinformatics/btm404
10.1093/molbev/msw054
10.1093/bioinformatics/btu817
10.1038/nmeth.1701
10.1038/nprot.2007.131
10.1093/nar/30.1.325
10.1016/j.molp.2020.06.009
10.1006/meth.2001.1262
10.1016/j.gene.2013.12.057
10.1590/1519-6984.259326
| null |
[
"Brassica napus",
"cis-element",
"expression analysis",
"phosphate stress",
"purple acid phosphatases (PAP)",
"salt stress"
] |
2025-02-13
|
Purple acid phosphatases (PAPs) play a key role in phosphorus (P) assimilation and redistribution in plants, catalyzing the hydrolysis of phosphate esters to produce inorganic phosphate (Pi). In this study, a total of 77
|
[
{
"affiliation": "Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Huanggang 438000, China.\nCollege of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Hongyuan",
"initials": "H",
"lastname": "Du"
},
{
"affiliation": "College of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Ruiqian",
"initials": "R",
"lastname": "Zhang"
},
{
"affiliation": "College of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Qingxue",
"initials": "Q",
"lastname": "Zhang"
},
{
"affiliation": "College of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Xun",
"initials": "X",
"lastname": "Shi"
},
{
"affiliation": "College of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Jiaxue",
"initials": "J",
"lastname": "Wang"
},
{
"affiliation": "Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Huanggang 438000, China.\nCollege of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Qian",
"initials": "Q",
"lastname": "Peng"
},
{
"affiliation": "Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Huanggang 438000, China.\nCollege of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Asfa",
"initials": "A",
"lastname": "Batool"
},
{
"affiliation": "Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization, Huanggang 438000, China.\nCollege of Biology and Agriculture Resources, Huanggang Normal University, Huanggang 438000, China.",
"collective": null,
"firstname": "Shisheng",
"initials": "S",
"lastname": "Li"
}
] |
Plants (Basel, Switzerland)
| null |
39943024
15012223
33508131
33873400
20142416
21562330
32824996
32943451
29650148
34402946
14740011
12021284
20357138
14585503
18208471
33679819
25173632
26105827
21143719
21948626
26042133
28887557
30414420
31010077
39207505
24528675
21941000
25246445
20348213
34487166
19633233
28116829
32270183
25146293
29844974
38377886
18716755
20838596
36417239
32936937
15310827
20051986
28502977
28179909
32455955
11097425
25657119
30881369
34755871
33125078
10592234
17846036
27004904
3447015
25504850
10027275
21959131
17446895
11928486
11752327
32585190
11846609
24406618
35703626
|
Identification and Expression Analysis of Acid Phosphatase Gene (
| null | null | null | null | null | null |
null |
Copyright © 2024, Choudhuri et al.
|
10.7759/cureus.73147
| null |
[
"antifungal resistance",
"bronchopleural fistula",
"candida auris",
"critical care infection",
"fungal pleural effusion",
"hydropneumothorax",
"icu-acquired infection",
"invasive candidiasis",
"multidrug-resistant fungal infection",
"posaconazole"
] |
2024-12-09
|
[
{
"affiliation": "Critical Care and Rheumatology, Parkview Super Speciality Hospital, Kolkata, IND.",
"collective": null,
"firstname": "Bodhisatwa",
"initials": "B",
"lastname": "Choudhuri"
},
{
"affiliation": "Critical Care, Parkview Super Speciality Hospital, Kolkata, IND.",
"collective": null,
"firstname": "Madhuparna",
"initials": "M",
"lastname": "Chakraborty"
},
{
"affiliation": "Pulmonology, ILS Hospital, Howrah, IND.",
"collective": null,
"firstname": "Pratik",
"initials": "P",
"lastname": "Biswas"
}
] |
Cureus
| null |
39650922
29167291
28333181
37647837
33085444
34992473
30521186
26679628
38066698
38238403
36421245
|
A Unique Case of Candida auris Infection Presenting With Hydropneumothorax and Bronchopleural Fistula: A Diagnostic and Therapeutic Challenge.
| null | null | null | null | null | null |
|
Non-functional adrenal adenomas are associated with increased CIMT and CVR. Early stages of cardiovascular remodelling can be observed in asymptomatic NFAI patients.
| null |
10.5603/ep.95139
|
The NFAI group showed significantly higher sodium (p = 0.02) and glucose levels in the 2-h oral glucose tolerance test (OGTT) (p = 0.04), a higher CIMT (p < 0.01), and a higher CVR calculated according to the SCORE algorithm (p = 0.03). The estimated glomerular filtration rate (eGFR) was higher in the NFAI group (p = 0.015). Hypertension (p < 0.01) and IGT (p = 0.026) were more common in the NFAI group. Statistically significant positive correlations were found between CIMT and age (r = 0.373, p = 0.003), waist circumference (r = 0.316, p = 0.029), diastolic blood pressure (r = 0.338, p = 0.019), and CVR based on the SCORE algorithm (r = 0.43, p = 0.004). There was a statistically significant positive correlation between CIMT and serum cortisol levels after 1 mg dexamethasone suppression test (r = 0.33, p = 0.02).
|
[
"cardiovascular risk",
"intima-media thickness",
"nonfunctional adrenal incidentaloma"
] |
2023-11-23
|
Adrenal incidentaloma (AI) secreting small amounts of glucocorticoids may cause morphological and functional changes in the blood vessels. Early stages of cardiovascular remodeling may be observed among asymptomatic patients with AI. But it is unclear whether the nonfunctional adrenal incidentalomas (NFAI) may also be a risk factor for cardiovascular diseases. The aim of this study was to determine the relationship between NFAI, carotid intima-media thickness (CIMT), and cardiovascular risk (CVR) based on Systematic Coronary Risk Evaluation (SCORE) prediction models for Europe.
This study from a single centre in Poland included 48 NFAI patients and 44 individuals in the control group matched for age, sex, and body mass index (BMI). All participants underwent adrenal imaging, biochemical evaluation, measurement of CIMT, and assessment of the 10-year risk of cardiovascular mortality based on the SCORE algorithm. Hormonal evaluation was conducted in AI patients.
The NFAI group showed significantly higher sodium (p = 0.02) and glucose levels in the 2-h oral glucose tolerance test (OGTT) (p = 0.04), a higher CIMT (p < 0.01), and a higher CVR calculated according to the SCORE algorithm (p = 0.03). The estimated glomerular filtration rate (eGFR) was higher in the NFAI group (p = 0.015). Hypertension (p < 0.01) and IGT (p = 0.026) were more common in the NFAI group. Statistically significant positive correlations were found between CIMT and age (r = 0.373, p = 0.003), waist circumference (r = 0.316, p = 0.029), diastolic blood pressure (r = 0.338, p = 0.019), and CVR based on the SCORE algorithm (r = 0.43, p = 0.004). There was a statistically significant positive correlation between CIMT and serum cortisol levels after 1 mg dexamethasone suppression test (r = 0.33, p = 0.02).
Non-functional adrenal adenomas are associated with increased CIMT and CVR. Early stages of cardiovascular remodelling can be observed in asymptomatic NFAI patients.
|
[
{
"affiliation": "Clinic of Endocrinology, Diabetology, and Internal Medicine, Department of Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland. [email protected].",
"collective": null,
"firstname": "Magdalena",
"initials": "M",
"lastname": "Szychlińska"
},
{
"affiliation": "Department of Imaging, Provincial Specialist Hospital in Olsztyn, Olsztyn, Poland.",
"collective": null,
"firstname": "Magdalena",
"initials": "M",
"lastname": "Rzeczkowska"
},
{
"affiliation": "Clinic of Endocrinology, Diabetology, and Internal Medicine, Department of Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.",
"collective": null,
"firstname": "Wojciech",
"initials": "W",
"lastname": "Matuszewski"
},
{
"affiliation": "Clinic of Endocrinology, Diabetology, and Internal Medicine, Department of Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.",
"collective": null,
"firstname": "Elżbieta",
"initials": "E",
"lastname": "Bandurska-Stankiewicz"
}
] |
Endokrynologia Polska
| null |
37994583
|
Could a nonfunctional adrenal incidentaloma be a risk factor for increased carotid intima-media thickness and 10-year cardiovascular mortality based on the SCORE algorithm? A study from a single centre in Poland.
| null | null | null | null | null | null |
null | null |
10.3390/jimaging11020067
10.1155/2014/597368
10.3390/s20226442
10.1016/j.procs.2013.06.104
10.1007/s10694-020-00986-y
10.1109/TCSVT.2015.2392531
10.1155/2018/7612487
10.1016/j.proeng.2017.12.034
10.1109/TPAMI.2016.2577031
10.1007/s11263-015-0816-y
| null |
[
"attention mechanisms",
"backbone network",
"convolutional neural networks",
"forest fire detection",
"object detection"
] |
2025-02-25
|
This study explores a method of detecting smoke plumes effectively as the early sign of a forest fire. Convolutional neural networks (CNNs) have been widely used for forest fire detection; however, they have not been customized or optimized for smoke characteristics. This paper proposes a CNN-based forest smoke detection model featuring novel backbone architecture that can increase detection accuracy and reduce computational load. Since the proposed backbone detects the plume of smoke through different views using kernels of varying sizes, it can better detect smoke plumes of different sizes. By decomposing the traditional square kernel convolution into a depth-wise convolution of the coordinate kernel, it can not only better extract the features of the smoke plume spreading along the vertical dimension but also reduce the computational load. An attention mechanism was applied to allow the model to focus on important information while suppressing less relevant information. The experimental results show that our model outperforms other popular ones by achieving detection accuracy of up to 52.9 average precision (AP) and significantly reduces the number of parameters and giga floating-point operations (GFLOPs) compared to the popular models.
|
[
{
"affiliation": "Department of Electrical, Electronic and Computer Engineering, University of Ulsan, Ulsan 44610, Republic of Korea.",
"collective": null,
"firstname": "Quy-Quyen",
"initials": "QQ",
"lastname": "Hoang"
},
{
"affiliation": "Department of Electrical, Electronic and Computer Engineering, University of Ulsan, Ulsan 44610, Republic of Korea.",
"collective": null,
"firstname": "Quy-Lam",
"initials": "QL",
"lastname": "Hoang"
},
{
"affiliation": "Department of Electrical, Electronic and Computer Engineering, University of Ulsan, Ulsan 44610, Republic of Korea.",
"collective": null,
"firstname": "Hoon",
"initials": "H",
"lastname": "Oh"
}
] |
Journal of imaging
| null |
39997569
33187292
27295650
|
An Efficient Forest Smoke Detection Approach Using Convolutional Neural Networks and Attention Mechanisms.
| null | null | null | null | null | null |
LLR of benign SLTs shows all the advantages of laparoscopy. In the case of malignant lesions, greater experience is needed to confirm the safety and effectiveness of the open approach.
| null |
10.1016/s0009-739x(05)70925-8
|
There was no intra- or postoperative mortality. With CLH the LLR was completed in five patients (62%), whereas with ALH there were no conversions. Only one of the 13 resected patients required transfusion. Seventeen nodules were excised in the 13 LLR, and 12 of 17 required the Pringle maneuver. The mean length of hospital stay was 4.9 days (3-14 days). Only one female patient (7.7%) developed an infected hematoma, requiring radiological drainage.
|
[] |
2006-01-20
|
Laparoscopic liver resection (LLR) of solid liver tumors (SLT) has not become widespread due to technical problems, the risk of air embolism, and possible tumoral spread in malignant lesions. We present our experience of LLR in SLT.
Between January 2003 and May 2005, we performed the laparoscopic approach in 16 patients with SLT. Preoperative diagnosis was liver metastases from colorectal carcinoma in 11 patients and benign tumor in the remaining five patients. Five of the lesions were located in the left lobe, another 10 in the right lobe (two in S. V, four in S. VI and four in S. VII) and the remaining lesion was bilobar (S. III and VI). LLRs were performed by complete laparoscopic hepatectomy (CLH) (n=8) and assisted laparoscopic hepatectomy (ALH) (n=8). LLR was completed in 13 patients (81%). Surgical technique (n=13) consisted of three left lobectomies, one with partial resection of S. IV, three bisegmentectomies (two of S. VI and VII and one of S. III and IV, the latter associated with metastasectomy in S. VIII), five segmentectomies (one of S. II, two of S. V and two of S. VI, one of the latter associated with metastasectomy in S. VII) and two local resections of benign tumors.
There was no intra- or postoperative mortality. With CLH the LLR was completed in five patients (62%), whereas with ALH there were no conversions. Only one of the 13 resected patients required transfusion. Seventeen nodules were excised in the 13 LLR, and 12 of 17 required the Pringle maneuver. The mean length of hospital stay was 4.9 days (3-14 days). Only one female patient (7.7%) developed an infected hematoma, requiring radiological drainage.
LLR of benign SLTs shows all the advantages of laparoscopy. In the case of malignant lesions, greater experience is needed to confirm the safety and effectiveness of the open approach.
|
[
{
"affiliation": "Unidad de Cirugía Hepática y Trasplante Hepático, Hospital Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain. [email protected]",
"collective": null,
"firstname": "Ricardo",
"initials": "R",
"lastname": "Robles"
},
{
"affiliation": null,
"collective": null,
"firstname": "Beatriz",
"initials": "B",
"lastname": "Abellán"
},
{
"affiliation": null,
"collective": null,
"firstname": "Caridad",
"initials": "C",
"lastname": "Marín"
},
{
"affiliation": null,
"collective": null,
"firstname": "Juan Angel",
"initials": "JA",
"lastname": "Fernández"
},
{
"affiliation": null,
"collective": null,
"firstname": "Pablo",
"initials": "P",
"lastname": "Ramírez"
},
{
"affiliation": null,
"collective": null,
"firstname": "Dolores",
"initials": "D",
"lastname": "Morales"
},
{
"affiliation": null,
"collective": null,
"firstname": "María",
"initials": "M",
"lastname": "Ramírez"
},
{
"affiliation": null,
"collective": null,
"firstname": "Francisco",
"initials": "F",
"lastname": "Sánchez"
},
{
"affiliation": null,
"collective": null,
"firstname": "Pascual",
"initials": "P",
"lastname": "Parrilla"
}
] |
Cirugia espanola
| null |
16420832
|
[Laparoscopic resection of solid liver tumors. Presentation of our experience].
| null | null | null | null | null | null |
null | null |
10.3390/ijerph18136687
10.1093/bja/aet198
10.1093/bja/aew172
10.1093/bja/aeu064
10.1111/anae.13053
10.1111/anae.14814
10.1097/AAP.0000000000000406
10.1097/ACO.0000000000000641
10.1097/AAP.0b013e318294fe4b
10.1097/ALN.0000000000003145
10.1177/0310057X1804600507
10.1097/AAP.0b013e3181d24529
10.1111/aas.13300
| null |
[
"continuous peripheral nerve block",
"dislocation of catheter",
"femoral triangle block",
"suture-method catheter"
] |
2021-07-03
|
Catheter dislocation with continuous peripheral nerve blocks represents a major problem in clinical settings. There is a range of factors affecting the incidence of catheter dislocation, including catheter type. This study aimed to assess the incidence of suture-method catheter (SMC) dislocation 24 h after total knee arthroplasty (TKA), with continuous femoral nerve block (CFNB) and continuous femoral triangle block (CFTB), respectively. In the prospective randomized trial, 40 patients qualified for TKA with SMC and were divided into two groups, those who received CFNB (Group 1,
|
[
{
"affiliation": "Department of Anesthesiology and Intensive Care, Regional Specialist Teaching Hospital, 10-719 Olsztyn, Poland.\nDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, University of Warmia and Mazury, 10-719 Olsztyn, Poland.",
"collective": null,
"firstname": "Bulat",
"initials": "B",
"lastname": "Tuyakov"
},
{
"affiliation": "Department of Anesthesiology and Intensive Care, Regional Specialist Teaching Hospital, 10-719 Olsztyn, Poland.",
"collective": null,
"firstname": "Mateusz",
"initials": "M",
"lastname": "Kruszewski"
},
{
"affiliation": "Department of Anaesthesiology and Intensive Therapy, Faculty of Medicine, University of Warmia and Mazury, 10-719 Olsztyn, Poland.\nDepartment of Anaesthesiology and Intensive Care, Teaching University Hospital, 10-082 Olsztyn, Poland.",
"collective": null,
"firstname": "Lidia",
"initials": "L",
"lastname": "Glinka"
},
{
"affiliation": "Department of Anatomy, Faculty of Medicine, University of Warmia and Mazury, 10-719 Olsztyn, Poland.",
"collective": null,
"firstname": "Oksana",
"initials": "O",
"lastname": "Klonowska"
},
{
"affiliation": "2nd Department of Anesthesiology and Intensive Care, Medical University of Lublin, 20-081 Lublin, Poland.",
"collective": null,
"firstname": "Michal",
"initials": "M",
"lastname": "Borys"
},
{
"affiliation": "2nd Department of Anesthesiology and Intensive Care, Medical University of Lublin, 20-081 Lublin, Poland.",
"collective": null,
"firstname": "Pawel",
"initials": "P",
"lastname": "Piwowarczyk"
},
{
"affiliation": "Department of Anesthesiology and Intensive Care, Regional Specialist Teaching Hospital, 10-719 Olsztyn, Poland.\nDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, University of Warmia and Mazury, 10-719 Olsztyn, Poland.",
"collective": null,
"firstname": "Dariusz",
"initials": "D",
"lastname": "Onichimowski"
}
] |
International journal of environmental research and public health
| null |
34206188
23748198
27440634
24645150
25791369
31465115
27171822
30004954
23788073
31996555
30189820
20301819
30520017
|
Incidence of Suture-Method Catheter Dislocation with Femoral Nerve Block and Femoral Triangle Block after Total Knee Arthroplasty.
| null | null | null | null | null | null |
null | null |
10.1038/srep13525
10.3322/caac.20107
10.1016/j.radonc.2013.10.035
10.1016/j.ijrobp.
10.1016/j.ijrobp.
10.1038/bjc.2013.720
10.1007/s00405-010-1381-1
10.1097/MLG.0b013e31818208
10.1002/lary.23215
10.1016/j.radonc.2009.09.013
| null |
[] |
2015-09-02
|
This study is to identify significant dosimetric parameters for ear disorders in nasopharyngeal carcinoma (NPC) patients treated with intensity modulated therapy only. Ninety-seven patients with NPC were retrospectively reviewed. Organs at risk (OARs) in the auditory apparatus were contoured. Dose-volume histogram parameters were generated for the Eustachian tube (ET), tympanic cavity (TC), mastoid air cells, vestibular apparatus, cochlea and internal auditory canal (IAC). Ear disorders were rated 0 (none), 1 (mild) or 2 (severe) by a clinician blinded to radiation doses; Grade 2 ear disorders was the study end-point. Multivariate analysis revealed ET.D30 (dose to 30% of ET volume) >52.75 Gy and M.D0.5CC (dose to 0.5 ml of mastoid volume) >41.04 Gy (OR = 3.77, P = 0.012 and OR = 1.27, P = 0.033, respectively) were associated with Grade 2 ear disorders. Our results demonstrated that post-irradiation ear disorders remain a common late toxicity in NPC after IMRT. ET.D30 and M.D0.5CC should be considered during IMRT treatment plan optimization, review and approval.
|
[
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Ji-Jin",
"initials": "JJ",
"lastname": "Yao"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Guan-Qun",
"initials": "GQ",
"lastname": "Zhou"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Li",
"initials": "L",
"lastname": "Lin"
},
{
"affiliation": "Department of Medical Statistics and Epidemiology &Health Information Research Center &Guangdong Key Laboratory of Medicine, School of Public Health, Sun Yat-sen University, Guangzhou 510080, Guangdong Province, China.",
"collective": null,
"firstname": "Wang-Jian",
"initials": "WJ",
"lastname": "Zhang"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Ying-Lin",
"initials": "YL",
"lastname": "Peng"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Lei",
"initials": "L",
"lastname": "Chen"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Ling-Long",
"initials": "LL",
"lastname": "Tang"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Yan-Ping",
"initials": "YP",
"lastname": "Mao"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Jun",
"initials": "J",
"lastname": "Ma"
},
{
"affiliation": "Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, Guangdong Province, People's Republic of China.",
"collective": null,
"firstname": "Ying",
"initials": "Y",
"lastname": "Sun"
}
] |
Scientific reports
| null |
26323586
|
Dose-volume factors associated with ear disorders following intensity modulated radiotherapy in nasopharyngeal carcinoma.
| null | null | null | null | null | null |
null |
Copyright © 2019 Elsevier Ltd. All rights reserved.
|
10.1016/j.micpath.2019.04.032
| null |
[
"Growth characteristics",
"Probiotic",
"Stress tolerance",
"Weissella"
] |
2019-04-23
|
In this study, we isolated four Weissella confusa strains from the healthy horse feces to test their potential as equine probiotics. The identification and characteristics of these isolates were determined as per standard methods. Resistance and susceptibility of the isolated strains were tested to low pHs, different heat treatments, commonly used antibiotics and against the pathogenic strains of Salmonella, Pasteurella, Staphylococcus aureus, and Escherichia coli. After 3 h cultural in different pH medium, the 4 strains still had a certain amount of survival above pH 3.0. WH2 and WH4 were still viable at pH2.5. All the isolated strains showed proper growth at 60 °C while no strain survived at 80 °C. The inhibition of α-amylase, the scavenging ability of free radical DPPH· and hydroxyl free radical HO·were also investigated. The results showed that WH4 had highest inhibition rate of α-amylase activity and DPPH· free radical scavenging rate, and the inhibition rate of α-amylase activity was 24.09% and the DPPH· free radical scavenging rate was 35.78%. The inhibition rate ofα-amylase activity and DPPH· scavenging rate of free radicals in the other three strains were about 10%. The clearance rate of hydroxyl radical (HO·) in 4 strains was between 12% and 15%. The antibiotic susceptibilities varied for these four Weisella strains but all of them showed resistance against the frequently used equine antibiotics. All the four strains successfully suppressed the growth of standard strains in in vitro bacteriostasis experiment, which included Salmonella enteritidis (NTNC13349), Escherichia coli (C83902) and Staphylococcus aureus (BNCC186335). they also successfully suppressed the growth of state key laboratory isolating pathogens, which are Pasterurella multocida and Salmonella. Our findings suggest that the isolated strains of Weissella confusa can act as potential equine probiotics and should be explored further.
|
[
{
"affiliation": "College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.",
"collective": null,
"firstname": "Ying",
"initials": "Y",
"lastname": "Xia"
},
{
"affiliation": "College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.",
"collective": null,
"firstname": "Songkang",
"initials": "S",
"lastname": "Qin"
},
{
"affiliation": "College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China. Electronic address: [email protected].",
"collective": null,
"firstname": "Yaoqin",
"initials": "Y",
"lastname": "Shen"
}
] |
Microbial pathogenesis
| null |
31009656
|
Probiotic potential of Weissella strains isolated from horse feces.
| null | null | null | null | null | null |
null | null |
10.5603/EP.2015.0004
|
A novel Q248X mutation (nucleotide C to T transition at position 742 of the exon 3 of HNF1B gene, resulting in stop codon formation) was identified. Phenotypes of family members sharing this mutation are highly variable, and include previously known abnormalities of the urinary system and pancreas, diabetes mellitus of variable onset and severity, hyperinsulinaemia, insulin resistance, metabolic syndrome, elevated aminotransferases, hyperbilirubinemia, hyperamylasemia, short stature and cataracts. To the best of our knowledge, spina bifida occulta, pectus carinatum, and splenomegaly have not been previously reported.
|
[] |
2015-03-11
|
Hepatocyte transforming factor 1B-maturity onset diabetes mellitus of the young (HNF1B-MODY) is an autosomal dominant type of monogenic diabetes caused by a mutation in the gene encoding hepatocyte nuclear factor 1beta (HNF-1beta). The aim of this study was to determine if a HNF1B gene mutation was responsible for a dominantly inherited form of diabetes mellitus among the members of a three-generation Polish family.
The index subject was a 13-year-old boy with metabolic syndrome, spina bifida occulta, posterior urethral valves, congenital ureteropelvic junction obstruction, and a family history of diabetes of autosomal dominant trait of inheritance. We performed clinical and laboratory examinations of his family and sequenced the HNF1B gene.
A novel Q248X mutation (nucleotide C to T transition at position 742 of the exon 3 of HNF1B gene, resulting in stop codon formation) was identified. Phenotypes of family members sharing this mutation are highly variable, and include previously known abnormalities of the urinary system and pancreas, diabetes mellitus of variable onset and severity, hyperinsulinaemia, insulin resistance, metabolic syndrome, elevated aminotransferases, hyperbilirubinemia, hyperamylasemia, short stature and cataracts. To the best of our knowledge, spina bifida occulta, pectus carinatum, and splenomegaly have not been previously reported.
Our results broaden the spectrum of HNF1B gene mutations and HNF1B-MODY-related phenotypes.
|
[
{
"affiliation": "Department of Paediatrics, Oncology, Haematology and Diabetology, Medical University of Lodz, Poland. [email protected].",
"collective": null,
"firstname": "Anna",
"initials": "A",
"lastname": "Hogendorf"
},
{
"affiliation": null,
"collective": null,
"firstname": "Małgorzata",
"initials": "M",
"lastname": "Kosińska-Urbańska"
},
{
"affiliation": null,
"collective": null,
"firstname": "Maciej",
"initials": "M",
"lastname": "Borowiec"
},
{
"affiliation": null,
"collective": null,
"firstname": "Karolina",
"initials": "K",
"lastname": "Antosik"
},
{
"affiliation": null,
"collective": null,
"firstname": "Krystyna",
"initials": "K",
"lastname": "Wyka"
},
{
"affiliation": null,
"collective": null,
"firstname": "Wojciech",
"initials": "W",
"lastname": "Młynarski"
}
] |
Endokrynologia Polska
| null |
25754277
|
Atypical phenotypic features among carriers of a novel Q248X nonsense mutation in the HNF1B gene.
| null | null | null | null | null | null |
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