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This review will describe the available evidence relating to the known benefits ( preventive efficacy in rodent tumorigenesis models and limited human data from small randomised , controlled trials and epidemiological studies ) and risks ( cardiovascular and renal toxicity ) of coxib therapy for cancer chemoprevention .
{ "id": "C0007226", "pos": [ 240, 254 ], "name": "cardiovascular" }
{ "id": "C0595916", "pos": [ 259, 273 ], "name": "renal toxicity" }
0NA
The stria vascularis showed focal coagulation , vesicle formation , perforation and atrophy after irradiation through the otic capsule .
{ "id": "C0333641", "pos": [ 84, 91 ], "name": "atrophy" }
{ "id": "C0458699", "pos": [ 122, 134 ], "name": "otic capsule" }
0NA
The procedure reduced pressure in the right ventricle ( p = 0.008 ) and resolved the pulmonary insufficiency in all patients .
{ "id": "C0184661", "pos": [ 4, 13 ], "name": "procedure" }
{ "id": "C0034088", "pos": [ 85, 108 ], "name": "pulmonary insufficiency" }
0NA
This combination of CD4 T-cell epitopes - 11 of them not described before - may have the potential for inclusion in a vaccine against HIV-1 , allowing the immunization of genetically distinct populations .
{ "id": "C0020971", "pos": [ 155, 167 ], "name": "immunization" }
{ "id": "C0042210", "pos": [ 118, 125 ], "name": "vaccine" }
0NA
MPEG-PL-DTPA-Gd enhanced MRI ( 30 mumol Gd/kg bolus injection ) was performed 1 hour after torsion at 1.5 T using fat-suppressed three-dimensional fast spoiled gradient-recalled sequence for relative blood volume measurement and three-dimensional time-of-flight sequence for MR angiography ( MRA ) .
{ "id": "C0024485", "pos": [ 25, 28 ], "name": "MRI" }
{ "id": "C0243032", "pos": [ 292, 295 ], "name": "MRA" }
17method_of
Phenytoin ( PHT ) dosage adjustment in a clinical situation is difficult because of the nonlinear metabolism of the drug .
{ "id": "C0013227", "pos": [ 116, 120 ], "name": "drug" }
{ "id": "C0031507", "pos": [ 0, 9 ], "name": "Phenytoin" }
0NA
The attractiveness penalty imposed by facial paralysis is significant , with paralyzed faces considered markedly less attractive than normals .
{ "id": "C0015450", "pos": [ 87, 92 ], "name": "faces" }
{ "id": "C0015469", "pos": [ 38, 54 ], "name": "facial paralysis" }
0NA
However , the prevalence of viable myocardium in patients with ischemic cardiomyopathy is unknown .
{ "id": "C0027061", "pos": [ 35, 45 ], "name": "myocardium" }
{ "id": "C0349782", "pos": [ 63, 86 ], "name": "ischemic cardiomyopathy" }
11finding_site_of
The description of factors associated to cervical pre-neoplasic lesions is needed to establish strategies for mortality prevention .
{ "id": "C0221198", "pos": [ 64, 71 ], "name": "lesions" }
{ "id": "C0027530", "pos": [ 41, 49 ], "name": "cervical" }
0NA
We here describe a child with medial parietal AVM associated with cyst , without any history of hemorrhage or radiosurgery .
{ "id": "C0019080", "pos": [ 96, 106 ], "name": "hemorrhage" }
{ "id": "C0010709", "pos": [ 66, 70 ], "name": "cyst" }
0NA
The main linkages in descending order of concentration were : (1 - ---4)-linked glucose , (1 - ---4)-linked xylose , terminal galactose , (1 - ---4)-linked mannose , terminal arabinose and (1 - ---2)-linked rhamnose .
{ "id": "C0017725", "pos": [ 80, 87 ], "name": "glucose" }
{ "id": "C0043375", "pos": [ 108, 114 ], "name": "xylose" }
0NA
Difficulties in entering the digestive tube proper have been explained by the presence of filtrating and triturating organs in the mouth parts of the beetles .
{ "id": "C1299586", "pos": [ 0, 12 ], "name": "Difficulties" }
{ "id": "C0017189", "pos": [ 29, 43 ], "name": "digestive tube" }
0NA
Methods for ex vivo isolation of fetal cells for transplantation are described .
{ "id": "C0040732", "pos": [ 49, 64 ], "name": "transplantation" }
{ "id": "C0204727", "pos": [ 20, 29 ], "name": "isolation" }
0NA
The objective of this study is to determine the incidence and risk factors of retinopathy of prematurity ( ROP ) in extremely low birth weight ( ELBW ) Chinese infants .
{ "id": "C0021294", "pos": [ 93, 104 ], "name": "prematurity" }
{ "id": "C0035344", "pos": [ 107, 110 ], "name": "ROP" }
5cause_of
Placentas were evaluated for evidence of villitis , chorioamnionitis , and funisitis .
{ "id": "C0008495", "pos": [ 52, 68 ], "name": "chorioamnionitis" }
{ "id": "C1270169", "pos": [ 41, 49 ], "name": "villitis" }
0NA
We evaluated additional catheterized and injected animals at 48 hours using physical examination , T2 MR images , and postmortem brain histologic specimens .
{ "id": "C0031809", "pos": [ 76, 96 ], "name": "physical examination" }
{ "id": "C0004398", "pos": [ 118, 128 ], "name": "postmortem" }
17method_of
Acute poisoning with organophosphate compounds can cause chronic neuropsychological disabilities not prevented by standard antidotes of atropine and pralidoxime .
{ "id": "C0071808", "pos": [ 149, 160 ], "name": "pralidoxime" }
{ "id": "C0004259", "pos": [ 136, 144 ], "name": "atropine" }
0NA
The purpose of this contribution is to investigate the pathophysiology of the abnormal endometrial development in hyperstimulated IVF cycles .
{ "id": "C0205161", "pos": [ 78, 86 ], "name": "abnormal" }
{ "id": "C0015915", "pos": [ 130, 133 ], "name": "IVF" }
0NA
After 30 minutes of ischemia , P-selectin expression increased by 41 % , 25 % , and 14 % in the CMJ , cortex , and the medulla , respectively , compared to controls .
{ "id": "C0022116", "pos": [ 20, 28 ], "name": "ischemia" }
{ "id": "C0001614", "pos": [ 102, 108 ], "name": "cortex" }
0NA
An era of cataloging epigenetic marks of the various diseased states has recently commenced , including those within the genes responsible for atherosclerosis , ischemia , hypertension and heart failure .
{ "id": "C0018801", "pos": [ 189, 202 ], "name": "heart failure" }
{ "id": "C0022116", "pos": [ 161, 169 ], "name": "ischemia" }
0NA
There were no differences concerning cardiovascular disease , smoking habits , or short-term metabolic control between patients who healed primarily or after an amputation .
{ "id": "C0002688", "pos": [ 161, 171 ], "name": "amputation" }
{ "id": "C0007222", "pos": [ 37, 59 ], "name": "cardiovascular disease" }
0NA
A methanogenic coccoid organism , Methanosarcina mazei LYC , was isolated from alkaline sediment obtained from an oil exploration drilling site .
{ "id": "C1280903", "pos": [ 118, 129 ], "name": "exploration" }
{ "id": "C0028908", "pos": [ 114, 117 ], "name": "oil" }
0NA
Na(+)-dependent uridine transport into liver plasma membrane vesicles from partially hepatectomized and sham-operated rats was studied .
{ "id": "C0333262", "pos": [ 61, 69 ], "name": "vesicles" }
{ "id": "C0023884", "pos": [ 39, 44 ], "name": "liver" }
0NA
Genetic predisposition to early onset of occlusive vascular diseases , including coronary artery disease , ischemic stroke , and Moyamoya disease , may represent varying presentations of a common underlying dysregulation of vascular smooth muscle cell proliferation .
{ "id": "C0334094", "pos": [ 252, 265 ], "name": "proliferation" }
{ "id": "C0010054", "pos": [ 81, 104 ], "name": "coronary artery disease" }
0NA
These clinical results confirm the value of screw fixation at several cephalic anchorage sites ( demonstrated biomechanically ) in true cervical fractures .
{ "id": "C0185023", "pos": [ 50, 58 ], "name": "fixation" }
{ "id": "C0005975", "pos": [ 44, 49 ], "name": "screw" }
0NA
The commonest causes of death were pre-eclampsia and eclampsia ( 23 ) , septicaemia ( 14 ) , haemorrhage ( 13 ) and ruptured uterus ( 11 ) .
{ "id": "C0019080", "pos": [ 93, 104 ], "name": "haemorrhage" }
{ "id": "C0032914", "pos": [ 35, 48 ], "name": "pre-eclampsia" }
0NA
Our research showed that PET-CT could clearly add information about the histology of the tumour .
{ "id": "C0027651", "pos": [ 89, 95 ], "name": "tumour" }
{ "id": "C1699633", "pos": [ 25, 31 ], "name": "PET-CT" }
0NA
The skin was cut , the temporal muscle was retracted , and the right distal MCA was observed through the skull .
{ "id": "C0037303", "pos": [ 105, 110 ], "name": "skull" }
{ "id": "C0444099", "pos": [ 4, 8 ], "name": "skin" }
0NA
The results showed that , for the glucose in the blood plasma solution and Intralipid-2 % solution , after the correction of the background which has the similar optical characteristics with the sample , the prediction precision of multivariate model for glucose concentration has been improved by 25.9 % and 40.1 % , respectively .
{ "id": "C0017725", "pos": [ 34, 41 ], "name": "glucose" }
{ "id": "C0427743", "pos": [ 255, 276 ], "name": "glucose concentration" }
6component_of
ATRA mediated by RARα increased AQP3 gene and protein expression in human vaginal mucosal epithelial cells .
{ "id": "C0042232", "pos": [ 74, 81 ], "name": "vaginal" }
{ "id": "C0026724", "pos": [ 82, 89 ], "name": "mucosal" }
0NA
Hypothermia preserves GSH synthesis during intestinal I/R injury , and this could protect from further tissue damage .
{ "id": "C0010957", "pos": [ 103, 116 ], "name": "tissue damage" }
{ "id": "C3263722", "pos": [ 58, 64 ], "name": "injury" }
3associated_morphology_of
The mutants can grow for an extended period of time in minimal medium supplemented with amino acids and BU , in which the sensitive parental strain ( Bu(+ ) ) undergoes rapid cell death .
{ "id": "C0002520", "pos": [ 88, 99 ], "name": "amino acids" }
{ "id": "C0020517", "pos": [ 122, 131 ], "name": "sensitive" }
0NA
Fish immune systems must be able to cope with pathogens over a wide temperature range .
{ "id": "C0020962", "pos": [ 5, 19 ], "name": "immune systems" }
{ "id": "C0005903", "pos": [ 68, 79 ], "name": "temperature" }
0NA
The gastrointestinal tracts of seven bat species ( Pipistrellus pipistrellus , Plecotus auritus , Myotis bechsteinii , Myotis nattereri , Myotis daubentonii , Myotis myotis , and Nyctalus leisleri ) were tested for chitinolytic activity by diffusion assay .
{ "id": "C0017189", "pos": [ 4, 27 ], "name": "gastrointestinal tracts" }
{ "id": "C0006298", "pos": [ 37, 40 ], "name": "bat" }
0NA
In each patient the defect was located low in the atrial septum adjacent to the inferior vena cava .
{ "id": "C0225836", "pos": [ 50, 63 ], "name": "atrial septum" }
{ "id": "C0042458", "pos": [ 80, 98 ], "name": "inferior vena cava" }
0NA
This inflammatory response perturbs the local immune response of the neighboring gut tissue and leads to hyperplasia .
{ "id": "C0020507", "pos": [ 105, 116 ], "name": "hyperplasia" }
{ "id": "C0301872", "pos": [ 46, 61 ], "name": "immune response" }
0NA
We review the expression , molecular interactions , and pathophysiological functions of CD47 in the cardiovascular and immune systems .
{ "id": "C0007226", "pos": [ 100, 114 ], "name": "cardiovascular" }
{ "id": "C0020962", "pos": [ 119, 133 ], "name": "immune systems" }
0NA
In patients with CRS without polyps or mucocele , 59 of 100 ( 59 % ) had frontal pain , with 21 of 38 ( 55 % ) with complete opacification having pain .
{ "id": "C0032584", "pos": [ 29, 35 ], "name": "polyps" }
{ "id": "C0010278", "pos": [ 17, 20 ], "name": "CRS" }
0NA
The interaction of a single beta hinge with a clathrin triskelion is weak , and we propose that recruitment of cytosolic clathrin to a forming coated pit involves simultaneous contacts between the legs of single clathrin trimers and the beta hinges of two or three membrane-bound AP complexes .
{ "id": "C1140621", "pos": [ 197, 201 ], "name": "legs" }
{ "id": "C0271510", "pos": [ 96, 107 ], "name": "recruitment" }
0NA
Also , of relevance was the down regulation of xanthine and bilirubin-derived metabolites such as urobilinogen and stercobilin after moderate wine consumption .
{ "id": "C0870883", "pos": [ 78, 89 ], "name": "metabolites" }
{ "id": "C0043314", "pos": [ 47, 55 ], "name": "xanthine" }
0NA
Brain MDA content and 4-HNE level in hippocampus CA1 were much lower in treatment group than in model group .
{ "id": "C0006104", "pos": [ 0, 5 ], "name": "Brain" }
{ "id": "C0019564", "pos": [ 37, 48 ], "name": "hippocampus" }
0NA
This brief intervention is feasible , is acceptable to staff , and may improve burnout and staff attitudes .
{ "id": "C0476644", "pos": [ 79, 86 ], "name": "burnout" }
{ "id": "C0184661", "pos": [ 11, 23 ], "name": "intervention" }
0NA
On admission , 338 ( 55.0 % ) mobilised independently 52.2 % had no change in their pre-fracture mobility at 1   year following their treatment .
{ "id": "C0184666", "pos": [ 3, 12 ], "name": "admission" }
{ "id": "C0080078", "pos": [ 97, 105 ], "name": "mobility" }
0NA
Thrombosis of the great vessels , and especially of the aorta , is rare in neonates .
{ "id": "C0005847", "pos": [ 24, 31 ], "name": "vessels" }
{ "id": "C0040053", "pos": [ 0, 10 ], "name": "Thrombosis" }
0NA
The serum of 90 per cent of drug addicts contains one of the HBV markers , and 20 per cent of them carry an anti-D antibody which is more often present in HBs Ag-positive subjects but may also be found in those who are positive for anti-HBs and anti HBc antibodies .
{ "id": "C0229671", "pos": [ 4, 9 ], "name": "serum" }
{ "id": "C0019163", "pos": [ 61, 64 ], "name": "HBV" }
0NA
MeCP2 and DNA methylation regulate RPE transdifferentiation and may be involved in the pathogenesis of PVR .
{ "id": "C0035322", "pos": [ 35, 38 ], "name": "RPE" }
{ "id": "C0242852", "pos": [ 103, 106 ], "name": "PVR" }
11finding_site_of
Reflection coefficients of urea , ethanol , and glycerol were derived by means of streaming potentials .
{ "id": "C0017861", "pos": [ 48, 56 ], "name": "glycerol" }
{ "id": "C0001962", "pos": [ 34, 41 ], "name": "ethanol" }
0NA
Regression modeling identified five variables statistically related to the probability of admission : age , triage score , heart rate , diastolic blood pressure , and chief complaint .
{ "id": "C0184666", "pos": [ 90, 99 ], "name": "admission" }
{ "id": "C0018810", "pos": [ 123, 133 ], "name": "heart rate" }
0NA
The procedure has been developed especially for soil pollutants , for which an application is described .
{ "id": "C0184661", "pos": [ 4, 13 ], "name": "procedure" }
{ "id": "C0185125", "pos": [ 79, 90 ], "name": "application" }
0NA
Antral mucosal specimens were processed for conventional staining procedures and immunocytochemistry for both the light and electron micro-scope .
{ "id": "C0026724", "pos": [ 7, 14 ], "name": "mucosal" }
{ "id": "C0242349", "pos": [ 81, 100 ], "name": "immunocytochemistry" }
0NA
During this period 65 URS procedures were performed to treat post-ESWL ureteral obstruction , and 22 to push the stone up to the kidney for subsequent ESWL treatment .
{ "id": "C0006736", "pos": [ 113, 118 ], "name": "stone" }
{ "id": "C0015359", "pos": [ 151, 155 ], "name": "ESWL" }
8direct_morphology_of
Gingival health was evaluated before and after the experimental period by assessing gingival and plaque indices and gingival crevicular fluid volume .
{ "id": "C0017562", "pos": [ 84, 92 ], "name": "gingival" }
{ "id": "C0011389", "pos": [ 97, 103 ], "name": "plaque" }
0NA
Hypertension , chronic pulmonary disease , arthritis , and heart disease were found to affect at least 15 % of the study population .
{ "id": "C0020538", "pos": [ 0, 12 ], "name": "Hypertension" }
{ "id": "C0018799", "pos": [ 59, 72 ], "name": "heart disease" }
0NA
None of the patients was positive for CIN 2 or any other lesions .
{ "id": "C0221198", "pos": [ 57, 64 ], "name": "lesions" }
{ "id": "C0206708", "pos": [ 38, 41 ], "name": "CIN" }
0NA
We also compared the effects of isoflurane ( 2 % ) inhalation anesthesia , intraperitoneal propofol ( 50 or 100 mg/kg ) , and pentobarbital ( 50 mg/kg ) on ECG in mice .
{ "id": "C0030883", "pos": [ 126, 139 ], "name": "pentobarbital" }
{ "id": "C0022180", "pos": [ 32, 42 ], "name": "isoflurane" }
0NA
Amblyopia , defined as best corrected visual acuity of less than or equal to 6/9 and not attributable directly to any underlying structural abnormality of the eye or the visual pathway , was identified in 118 participants ( 3.2 % ) in BMES I , of whom 73 were re-examined in BMES II .
{ "id": "C0015392", "pos": [ 159, 162 ], "name": "eye" }
{ "id": "C0042812", "pos": [ 38, 51 ], "name": "visual acuity" }
0NA
For HCT the frequency of some complications is dependent on whether the transplant is allogenic or autologous .
{ "id": "C0040732", "pos": [ 72, 82 ], "name": "transplant" }
{ "id": "C0018935", "pos": [ 4, 7 ], "name": "HCT" }
0NA
The most serious etiology is amyloidosis ( AA variant ) with renal involvement , ultimately progressing to end-stage renal disease .
{ "id": "C0022646", "pos": [ 61, 66 ], "name": "renal" }
{ "id": "C0022661", "pos": [ 107, 130 ], "name": "end-stage renal disease" }
11finding_site_of
A number of medications have been used for PS , but midazolam is most commonly reported .
{ "id": "C0013227", "pos": [ 12, 23 ], "name": "medications" }
{ "id": "C0026056", "pos": [ 52, 61 ], "name": "midazolam" }
0NA
It also prevents the unnecessary medical evacuation of patients to RDH , particularly when no abnormality is detected on initial imaging .
{ "id": "C0442726", "pos": [ 109, 117 ], "name": "detected" }
{ "id": "C0011923", "pos": [ 129, 136 ], "name": "imaging" }
0NA
the impact of e-liquid with or without nicotine on the epididymis of rats using the same procedure .
{ "id": "C0184661", "pos": [ 89, 98 ], "name": "procedure" }
{ "id": "C0028040", "pos": [ 39, 47 ], "name": "nicotine" }
0NA
Feather edge preparation presents significantly more bleeding on probing and less gingival recession than the chamfer .
{ "id": "C0019080", "pos": [ 53, 61 ], "name": "bleeding" }
{ "id": "C0419358", "pos": [ 65, 72 ], "name": "probing" }
0NA
Retinal explants mounted on an 8 × 8 multi-electrode array were stimulated by applying 1 Hz cathodic-phase first biphasic current pulses .
{ "id": "C0035298", "pos": [ 0, 7 ], "name": "Retinal" }
{ "id": "C0034107", "pos": [ 130, 136 ], "name": "pulses" }
0NA
The median best visual acuity in the fellow eye was 20/160 .
{ "id": "C0015392", "pos": [ 44, 47 ], "name": "eye" }
{ "id": "C0042812", "pos": [ 16, 29 ], "name": "visual acuity" }
0NA
These are the antiretroviral drugs , atazanavir , indinavir and emtricitabine , the antibacterial gemifloxacin , rosuvastatine which is a cholesterol-lowering drug , the anti-cancer drug gefitinib and aprepitant for neurological disorders .
{ "id": "C1145759", "pos": [ 37, 47 ], "name": "atazanavir" }
{ "id": "C0376637", "pos": [ 50, 59 ], "name": "indinavir" }
0NA
Surgically and pharmaceutically uncontrollable pain in the forearm stump of a 28-year-old mine explosion victim of the Viet-Nam War , was successfully treated by electric pain control ( EPC ) , which led to his full rehabilitation .
{ "id": "C0034991", "pos": [ 216, 230 ], "name": "rehabilitation" }
{ "id": "C0543467", "pos": [ 0, 10 ], "name": "Surgically" }
0NA
Fifth , a combination of features in the malleus , incus , and stapes may indicate a slightly different relative positioning of either the tip of the incus long process or stapes footplate within the tympanic cavity in the Neandertal lineage .
{ "id": "C0038152", "pos": [ 63, 69 ], "name": "stapes" }
{ "id": "C0017589", "pos": [ 41, 48 ], "name": "malleus" }
0NA
All four limbs and the lower abdomen were compressed with constant pressure [ height ( cm ) divided by 13.6 mmHg ] once , for 3h , using stroke rehabilitation splints , while patients lay supine .
{ "id": "C0034991", "pos": [ 144, 158 ], "name": "rehabilitation" }
{ "id": "C0038454", "pos": [ 137, 143 ], "name": "stroke" }
0NA
Based on the findings of this study further research is necessary before urine TGF levels can be recommended as a routine screening test for SCC of the head and neck .
{ "id": "C0018670", "pos": [ 152, 156 ], "name": "head" }
{ "id": "C0027530", "pos": [ 161, 165 ], "name": "neck" }
0NA
The high affinity component was blocked by low concentrations of buspirone , spiperone and ergotamine .
{ "id": "C0028778", "pos": [ 32, 39 ], "name": "blocked" }
{ "id": "C0014710", "pos": [ 91, 101 ], "name": "ergotamine" }
0NA
Both vaccine types yielded similar control of tumor growth , but we found clear differences in their immune responses 10 days after DC immunization .
{ "id": "C0020971", "pos": [ 135, 147 ], "name": "immunization" }
{ "id": "C0042210", "pos": [ 5, 12 ], "name": "vaccine" }
0NA
Two-thirds of patients presented with combined injuries to the thorax or fractures .
{ "id": "C0817096", "pos": [ 63, 69 ], "name": "thorax" }
{ "id": "C0016658", "pos": [ 73, 82 ], "name": "fractures" }
0NA
Antenatal transvaginal ultrasound for assessing the risk of preterm delivery is an acceptable procedure for the majority of women .
{ "id": "C0151526", "pos": [ 60, 76 ], "name": "preterm delivery" }
{ "id": "C0184661", "pos": [ 94, 103 ], "name": "procedure" }
0NA
For moderate-grade lesions , both MR techniques are inaccurate predictors of degree of carotid stenosis and result in a significant overestimation of stenosis .
{ "id": "C0221198", "pos": [ 19, 26 ], "name": "lesions" }
{ "id": "C0007282", "pos": [ 87, 103 ], "name": "carotid stenosis" }
0NA
However , sex-specific evidence for the relationship between CKD and risk of stroke and its subtypes is still limited .
{ "id": "C1561643", "pos": [ 61, 64 ], "name": "CKD" }
{ "id": "C0038454", "pos": [ 77, 83 ], "name": "stroke" }
0NA
The variation in colony form is shown to depend on ( i ) the types of single carbon substrates ( sugars and sugar alcohols ) used in the growth medium , ( ii ) colony age , ( iii ) incubation temperature , ( iv ) light cycle and ( v ) substrate type .
{ "id": "C0242209", "pos": [ 97, 103 ], "name": "sugars" }
{ "id": "C0005903", "pos": [ 192, 203 ], "name": "temperature" }
0NA
Injury to solid viscera was categorized as minor in 32 ( 43 % ) , moderate in 18 ( 24 % ) , or severe in 25 ( 33 % ) according to an assessment of the percentage of parenchyma involved .
{ "id": "C0031809", "pos": [ 133, 143 ], "name": "assessment" }
{ "id": "C3263722", "pos": [ 0, 6 ], "name": "Injury" }
0NA
For those with stage IV disease or unfit for radical treatment , a variety of palliative modalities exist including stenting , laser photocoagulation , brachytherapy , and chemotherapy used singly or in combination , the latter providing encouraging improvement in survival over single-modality treatment .
{ "id": "C0006098", "pos": [ 152, 165 ], "name": "brachytherapy" }
{ "id": "C0013216", "pos": [ 172, 184 ], "name": "chemotherapy" }
0NA
Adult rat kidney also contained a slightly smaller mRNA at about 20 % the level in liver .
{ "id": "C0022646", "pos": [ 10, 16 ], "name": "kidney" }
{ "id": "C0023884", "pos": [ 83, 88 ], "name": "liver" }
0NA
In contrast to orchidectomy , deletion of neuronal AR did not alter body weight , body composition , hindlimb muscle mass , grip strength or wheel running .
{ "id": "C0023216", "pos": [ 101, 109 ], "name": "hindlimb" }
{ "id": "C0005910", "pos": [ 68, 79 ], "name": "body weight" }
0NA
Recently he returned to the clinic complaining of rigidity of the entire spine .
{ "id": "C0037949", "pos": [ 73, 78 ], "name": "spine" }
{ "id": "C0026837", "pos": [ 50, 58 ], "name": "rigidity" }
0NA
The fatal outcome of disseminated mucormycosis justifies a high index of suspicion and a maximal ( invasive ) diagnostic effort as localised infections might be cured by resection and amphotericin B.
{ "id": "C0015252", "pos": [ 170, 179 ], "name": "resection" }
{ "id": "C0026718", "pos": [ 34, 46 ], "name": "mucormycosis" }
0NA
Thus , it is important that raised blood pressure is both detected and effectively lowered .
{ "id": "C0442726", "pos": [ 58, 66 ], "name": "detected" }
{ "id": "C0005823", "pos": [ 35, 49 ], "name": "blood pressure" }
0NA
In summary , patients with thinner melanomas amenable to surgical resection had a better prognosis than those with more extensive , metastatic disease at presentation .
{ "id": "C0015252", "pos": [ 57, 75 ], "name": "surgical resection" }
{ "id": "C0033325", "pos": [ 89, 98 ], "name": "prognosis" }
0NA
The lung at birth is at the terminal-sac stage of development .
{ "id": "C0024109", "pos": [ 4, 8 ], "name": "lung" }
{ "id": "C0005615", "pos": [ 12, 17 ], "name": "birth" }
0NA
Niacin is the most effective medication in current clinical use for increasing high-density lipoprotein cholesterol .
{ "id": "C0013227", "pos": [ 29, 39 ], "name": "medication" }
{ "id": "C0027996", "pos": [ 0, 6 ], "name": "Niacin" }
0NA
Antihistamines are an important component of regimens for the prevention of anaphylaxis and anaphylactoid reactions in patients at risk , and may eventually have more widespread application in the perioperative setting .
{ "id": "C0199176", "pos": [ 62, 72 ], "name": "prevention" }
{ "id": "C0019590", "pos": [ 0, 14 ], "name": "Antihistamines" }
0NA
We conclude that an abundance of pretracheal soft tissue at the level of the vocal cords is a good predictor of difficult laryngoscopy in obese patients .
{ "id": "C0042930", "pos": [ 77, 88 ], "name": "vocal cords" }
{ "id": "C0023072", "pos": [ 122, 134 ], "name": "laryngoscopy" }
0NA
Piracetam , a new drug which is thought to enhance learning and memory consolidation , was given in a 3300 mg daily dose to half of a group of fifty-five ( 55 ) dyslexic boys aged eight to thirteen years in a twelve week , double-blind , placebo controlled study .
{ "id": "C0013227", "pos": [ 18, 22 ], "name": "drug" }
{ "id": "C0031977", "pos": [ 0, 9 ], "name": "Piracetam" }
0NA
Few data are available on the long-term effects of weight loss on 24-h blood pressure ( BP ) and left ventricular mass in overweight hypertensive patients .
{ "id": "C0497406", "pos": [ 122, 132 ], "name": "overweight" }
{ "id": "C0005823", "pos": [ 71, 85 ], "name": "blood pressure" }
0NA
Day-to-day precision studies on fresh and lyophilized normal and abnormal sera gave CV 's in the following ranges : aca , 1.8 % to 6.7 % ; Amylochrome , 3.0 % to 5.2 % ; and Coleman 91 , 4.5 % to 5.9 % .
{ "id": "C0205161", "pos": [ 65, 73 ], "name": "abnormal" }
{ "id": "C0085762", "pos": [ 116, 119 ], "name": "aca" }
0NA
Sulfur mustard ( SM ) is a chemical toxic which can cause severe permanent damages to lung tissues .
{ "id": "C0010957", "pos": [ 75, 82 ], "name": "damages" }
{ "id": "C0819757", "pos": [ 86, 98 ], "name": "lung tissues" }
0NA
In 37 children with one or more scars in one or both kidneys , scarring was significantly more frequent in the polar areas than in the lateral area .
{ "id": "C0022646", "pos": [ 53, 60 ], "name": "kidneys" }
{ "id": "C0241158", "pos": [ 32, 37 ], "name": "scars" }
0NA
Another patient gave a history of intramuscular injections of bovine RNA ( Regeneresen ) extracted from various organs including brain administered over a ten-year period .
{ "id": "C0006104", "pos": [ 129, 134 ], "name": "brain" }
{ "id": "C0021485", "pos": [ 48, 58 ], "name": "injections" }
0NA
The application of the multiple test concept in sequential sampling is investigated .
{ "id": "C0441621", "pos": [ 59, 67 ], "name": "sampling" }
{ "id": "C0185125", "pos": [ 4, 15 ], "name": "application" }
0NA
The most obvious advantage of colonoscopy is to establish the diagnosis at any level of the colon by direct observation of the mucosal surface and identification of any active bleeding and or responsible lesions .
{ "id": "C0009368", "pos": [ 92, 97 ], "name": "colon" }
{ "id": "C0009378", "pos": [ 30, 41 ], "name": "colonoscopy" }
9direct_procedure_site_of
The animals were killed 1 - 12 weeks after the operation ( four to six rats/group ) , and the grafts were removed and processed for microscopy .
{ "id": "C0332835", "pos": [ 94, 100 ], "name": "grafts" }
{ "id": "C0026018", "pos": [ 132, 142 ], "name": "microscopy" }
0NA
Metastatic lesions were not seen but there were implantations on the pericardium in one cat .
{ "id": "C0031050", "pos": [ 69, 80 ], "name": "pericardium" }
{ "id": "C0021107", "pos": [ 48, 61 ], "name": "implantations" }
0NA
The complete primary repair of exstrophy ( CPRE ) is a widely adopted approach that seeks to normalize anatomy at the initial repair , thereby allowing early bladder filling and cycling .
{ "id": "C0005682", "pos": [ 158, 165 ], "name": "bladder" }
{ "id": "C0043240", "pos": [ 126, 132 ], "name": "repair" }
0NA
The respiratory rate as determined by thermistor recording of nasal breath temperature was used as control .
{ "id": "C0231832", "pos": [ 4, 20 ], "name": "respiratory rate" }
{ "id": "C0005903", "pos": [ 75, 86 ], "name": "temperature" }
0NA