popV/tabula_muris_All_Smart-seq2

Popular Vote (popV) model for automated cell type annotation of single-cell RNA-seq data. We provide here pretrained models for plug-in use in your own analysis. Follow our tutorial to learn how to use the model for cell type annotation.

Model description

Ageing is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. Despite rapid advances over recent years, many of the molecular and cellular processes that underlie the progressive loss of healthy physiology are poorly understood. To gain a better insight into these processes, here we generate a single-cell transcriptomic atlas across the lifespan of Mus musculus that includes data from 23 tissues and organs. We found cell-specific changes occurring across multiple cell types and organs, as well as age-related changes in the cellular composition of different organs. Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence, genomic instability and changes in the immune system. This transcriptomic atlas—which we denote Tabula Muris Senis, or ‘Mouse Ageing Cell Atlas’—provides molecular information about how the most important hallmarks of ageing are reflected in a broad range of tissues and cell types.

Link to CELLxGENE: Link to the data in the CELLxGENE browser for interactive exploration of the data and download of the source data.

Training Code URL: Not provided by uploader.

Metrics

We provide here accuracies for each of the experts and the ensemble model. The validation set accuracies are computed on a 10% random subset of the data that was not used for training.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
microglial cell	1361	0.99	0.99	0.96	0.99	0.00	0.96	0.99	0.99	0.99
B cell	551	0.61	0.71	0.71	0.66	0.00	0.67	0.60	0.67	0.74
endothelial cell	488	0.77	0.84	0.79	0.70	0.00	0.68	0.86	0.85	0.90
mesenchymal stem cell of adipose tissue	449	0.88	0.89	0.75	0.64	0.00	0.78	0.93	0.89	0.92
basal cell of epidermis	390	0.86	0.90	0.83	0.84	0.00	0.86	0.91	0.88	0.92
fibroblast of cardiac tissue	343	0.93	0.93	0.75	0.64	0.00	0.68	0.96	0.92	0.95
hematopoietic stem cell	335	0.95	0.95	0.94	0.94	0.00	0.91	0.97	0.96	0.96
granulocyte	290	0.92	0.92	0.87	0.88	0.00	0.79	0.92	0.91	0.94
naive B cell	332	0.43	0.08	0.50	0.31	0.00	0.39	0.52	0.58	0.36
skeletal muscle satellite cell	258	0.97	0.98	0.94	0.87	0.00	0.88	0.97	0.96	0.97
endothelial cell of coronary artery	268	0.74	0.76	0.60	0.54	0.00	0.54	0.90	0.83	0.88
keratinocyte stem cell	257	0.94	0.93	0.94	0.81	0.00	0.91	0.95	0.94	0.96
myeloid cell	248	0.59	0.68	0.45	0.47	0.00	0.47	0.73	0.70	0.74
enterocyte of epithelium of large intestine	263	0.92	0.92	0.87	0.92	0.00	0.91	0.93	0.92	0.95
macrophage	236	0.38	0.52	0.43	0.45	0.00	0.43	0.53	0.55	0.60
basal cell	189	1.00	0.99	0.98	0.85	0.00	0.91	1.00	0.98	1.00
bronchial smooth muscle cell	210	0.94	0.94	0.85	0.64	0.00	0.06	0.95	0.94	0.96
oligodendrocyte	209	1.00	1.00	0.98	0.99	0.00	1.00	1.00	0.98	1.00
DN4 thymocyte	159	0.57	0.59	0.46	0.51	0.00	0.31	0.72	0.74	0.70
epithelial cell of large intestine	178	0.84	0.86	0.76	0.74	0.00	0.84	0.91	0.90	0.89
thymocyte	153	0.87	0.90	0.74	0.87	0.00	0.85	0.90	0.94	0.92
large intestine goblet cell	165	0.79	0.86	0.82	0.79	0.00	0.79	0.91	0.86	0.92
intestinal crypt stem cell	159	0.87	0.88	0.79	0.81	0.00	0.86	0.93	0.87	0.92
mesenchymal stem cell	169	0.69	0.78	0.59	0.47	0.00	0.65	0.84	0.83	0.85
bladder urothelial cell	121	0.97	0.95	0.91	0.88	0.00	0.95	0.99	0.99	0.98
type B pancreatic cell	129	0.98	0.98	0.93	0.96	0.00	0.98	0.98	0.96	0.98
fibroblast	131	0.56	0.62	0.32	0.28	0.00	0.53	0.85	0.72	0.79
T cell	122	0.40	0.41	0.41	0.42	0.00	0.39	0.53	0.51	0.49
monocyte	113	0.64	0.73	0.56	0.56	0.00	0.52	0.81	0.79	0.79
keratinocyte	121	0.79	0.90	0.70	0.71	0.00	0.79	0.92	0.86	0.89
CD4-positive, alpha-beta T cell	142	0.61	0.62	0.51	0.42	0.00	0.55	0.51	0.60	0.68
hepatocyte	96	0.93	0.94	0.95	0.91	0.00	0.94	0.96	0.94	0.96
CD8-positive, alpha-beta T cell	110	0.49	0.54	0.42	0.40	0.00	0.41	0.47	0.58	0.54
promonocyte	101	0.60	0.68	0.59	0.55	0.00	0.56	0.73	0.74	0.78
bladder cell	86	0.99	0.99	0.91	0.64	0.00	0.77	1.00	0.97	0.99
natural killer cell	89	0.72	0.72	0.63	0.72	0.00	0.70	0.68	0.76	0.78
precursor B cell	90	0.84	0.89	0.79	0.75	0.00	0.87	0.91	0.90	0.92
luminal epithelial cell of mammary gland	76	0.93	0.94	0.94	0.91	0.00	0.91	0.97	0.95	0.96
endothelial cell of hepatic sinusoid	58	0.93	0.97	0.94	0.85	0.00	0.84	0.96	0.93	0.97
astrocyte	57	0.95	0.96	0.91	0.94	0.00	0.96	0.96	0.94	0.97
immature B cell	53	0.59	0.51	0.43	0.35	0.00	0.48	0.58	0.57	0.72
pancreatic acinar cell	57	0.97	0.98	0.94	0.95	0.00	0.93	0.98	0.97	0.99
secretory cell	62	0.67	0.63	0.46	0.43	0.00	0.68	0.88	0.80	0.89
pancreatic A cell	65	0.91	0.93	0.89	0.90	0.00	0.94	0.95	0.94	0.95
epidermal cell	63	0.81	0.78	0.55	0.78	0.00	0.77	0.83	0.82	0.88
neuron	43	0.64	0.68	0.64	0.79	0.00	0.79	0.93	0.84	0.92
brain pericyte	42	0.78	0.88	0.77	0.68	0.00	0.81	0.99	0.90	0.89
fibroblast of lung	52	0.92	0.93	0.89	0.86	0.00	0.90	0.95	0.98	0.91
granulocytopoietic cell	36	0.85	0.82	0.79	0.80	0.00	0.75	0.90	0.83	0.87
kidney collecting duct epithelial cell	33	0.70	0.86	0.84	0.79	0.00	0.97	0.99	0.97	0.99
aortic endothelial cell	11	0.00	0.00	0.10	0.12	0.00	0.00	0.11	0.10	0.08
epithelial cell	39	0.38	0.14	0.42	0.37	0.00	0.39	0.54	0.59	0.60
late pro-B cell	41	0.83	0.94	0.90	0.76	0.00	0.86	0.99	0.91	0.97
basal epithelial cell of tracheobronchial tree	36	0.64	0.50	0.48	0.45	0.00	0.66	0.89	0.70	0.75
regular atrial cardiac myocyte	34	0.45	0.62	0.70	0.68	0.00	0.63	0.64	0.78	0.82
epithelial cell of proximal tubule	38	0.70	0.83	0.75	0.75	0.00	0.87	0.99	0.95	0.95
endocardial cell	39	0.95	0.91	0.90	0.78	0.00	0.88	0.99	0.92	0.96
myeloid dendritic cell	42	0.46	0.62	0.19	0.46	0.00	0.33	0.77	0.74	0.75
stromal cell	29	0.58	0.41	0.13	0.30	0.00	0.30	0.71	0.59	0.73
mature alpha-beta T cell	35	0.26	0.15	0.21	0.12	0.00	0.25	0.38	0.50	0.26
cardiac valve cell	28	0.85	0.88	0.83	0.72	0.00	0.86	0.90	0.92	0.89
pancreatic ductal cell	39	1.00	0.99	0.95	0.96	0.00	0.99	1.00	1.00	1.00
oligodendrocyte precursor cell	35	0.96	1.00	0.96	0.97	0.00	0.99	0.99	0.99	0.99
adventitial cell	34	0.00	0.48	0.36	0.08	0.00	0.43	0.73	0.60	0.60
chondrocyte	31	0.80	0.76	0.85	0.79	0.00	0.80	0.95	0.85	0.90
Kupffer cell	29	0.98	0.96	0.87	0.88	0.00	0.88	0.93	0.86	0.98
granulocyte monocyte progenitor cell	21	0.73	0.74	0.74	0.78	0.00	0.66	0.89	0.78	0.86
interneuron	24	0.67	0.65	0.40	0.75	0.00	0.79	0.98	0.92	0.96
myeloid leukocyte	19	0.19	0.10	0.19	0.21	0.00	0.18	0.29	0.52	0.35
classical monocyte	16	0.00	0.39	0.26	0.19	0.00	0.11	0.70	0.71	0.59
mature NK T cell	24	0.29	0.27	0.22	0.21	0.00	0.37	0.49	0.65	0.53
pancreatic D cell	19	0.94	1.00	0.84	0.92	0.00	0.95	0.97	0.92	0.97
brush cell of epithelium proper of large intestine	20	0.80	0.70	0.32	0.79	0.00	0.90	0.90	0.86	0.88
epithelial cell of thymus	20	0.44	0.00	0.24	0.50	0.00	0.41	0.49	0.42	0.48
enteroendocrine cell	10	0.90	0.69	0.55	0.67	0.00	0.74	1.00	0.95	0.95
leukocyte	16	0.00	0.48	0.20	0.34	0.00	0.42	0.54	0.86	0.74
neutrophil	15	0.00	0.00	0.11	0.00	0.00	0.14	0.36	0.56	0.29
kidney collecting duct principal cell	13	0.00	0.83	0.80	0.53	0.00	0.79	0.83	0.85	0.92
vein endothelial cell	15	0.50	0.42	0.11	0.44	0.00	0.81	0.93	0.74	0.80
neuroepithelial stem cell	22	0.43	0.09	0.43	0.65	0.00	0.64	0.85	0.76	0.82
non-classical monocyte	16	0.18	0.58	0.43	0.32	0.00	0.28	0.76	0.47	0.63
regular ventricular cardiac myocyte	14	0.75	0.00	0.86	0.75	0.00	0.81	1.00	0.97	0.96
kidney loop of Henle ascending limb epithelial cell	14	0.70	0.90	0.90	0.52	0.00	0.65	0.96	0.86	0.93
smooth muscle cell of trachea	13	0.00	0.00	0.36	0.35	0.00	0.31	0.61	0.33	0.48
professional antigen presenting cell	2	0.00	0.18	0.00	0.29	0.00	0.29	0.00	0.21	0.33
smooth muscle cell of the pulmonary artery	6	0.00	0.67	0.25	0.00	0.00	0.43	0.71	0.63	0.83
proerythroblast	12	0.00	0.27	0.21	0.44	0.00	0.08	0.50	0.40	0.33
medium spiny neuron	8	1.00	0.93	0.44	0.50	0.00	1.00	1.00	0.94	1.00
smooth muscle cell	13	0.00	0.82	0.25	0.13	0.00	0.83	0.93	0.92	0.92
endothelial cell of lymphatic vessel	8	0.44	0.50	0.93	0.53	0.00	0.62	0.94	0.76	0.89
neural stem cell	12	0.85	0.91	0.76	0.96	0.00	0.80	0.87	0.80	0.87
mesangial cell	8	0.00	0.40	0.00	0.33	0.00	0.14	0.67	0.77	0.55
megakaryocyte-erythroid progenitor cell	9	0.24	0.60	0.60	0.80	0.00	0.52	0.67	0.44	0.61
mucus secreting cell	8	0.52	0.42	0.71	0.62	0.00	0.76	0.94	0.94	0.80
early pro-B cell	7	0.59	0.73	0.44	0.43	0.00	0.78	0.77	0.80	0.86
pancreatic PP cell	6	0.00	0.44	0.00	0.50	0.00	0.77	0.77	0.77	0.60
basophil	10	0.48	0.57	0.78	0.78	0.00	0.54	0.87	0.75	0.87
ciliated columnar cell of tracheobronchial tree	9	0.71	0.89	0.94	0.74	0.00	0.72	0.84	0.75	1.00
dendritic cell	8	0.33	0.33	0.18	0.40	0.00	0.52	0.67	0.56	0.55
ependymal cell	7	0.44	0.67	0.44	0.67	0.00	0.71	1.00	0.83	0.92
Bergmann glial cell	2	0.67	0.67	1.00	0.57	0.00	1.00	0.80	1.00	1.00
pulmonary interstitial fibroblast	4	0.75	0.75	0.60	0.33	0.00	0.50	0.86	0.67	0.75
pancreatic stellate cell	3	0.86	1.00	0.86	0.80	0.00	0.40	0.67	0.67	0.86
regulatory T cell	4	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
pericyte	3	0.75	0.57	0.67	0.40	0.00	0.67	0.67	0.75	0.67
fibrocyte	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
respiratory basal cell	5	0.00	0.00	0.00	0.57	0.00	0.73	0.89	1.00	0.33
plasma cell	1	0.10	0.00	0.00	0.00	0.00	0.12	0.25	0.18	0.20
club cell	2	0.00	0.00	0.08	0.67	0.00	0.25	0.40	0.40	0.67
kidney interstitial fibroblast	1	0.00	0.00	0.00	0.00	0.00	0.40	0.00	1.00	0.00
lymphoid lineage restricted progenitor cell	2	0.67	0.00	0.67	0.00	0.00	0.50	1.00	1.00	0.67
intermediate monocyte	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
lymphocyte	1	0.00	0.00	0.00	0.00	0.00	0.67	1.00	1.00	0.00
lung macrophage	1	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
plasmacytoid dendritic cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00
lung neuroendocrine cell	0	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00	0.00

The train accuracies are computed on the training data.

Cell Type	N cells	celltypist	knn bbknn	knn harmony	knn on scvi	onclass	scanvi	svm	xgboost	Consensus Prediction
microglial cell	11907	0.99	0.99	0.95	0.99	0.00	0.96	0.99	0.99	0.99
B cell	5066	0.62	0.71	0.82	0.78	0.00	0.89	0.67	0.73	0.85
endothelial cell	4438	0.77	0.78	0.85	0.78	0.00	0.88	0.88	0.85	0.93
mesenchymal stem cell of adipose tissue	4276	0.86	0.87	0.82	0.75	0.00	0.94	0.93	0.90	0.95
basal cell of epidermis	3817	0.87	0.90	0.92	0.87	0.00	0.88	0.92	0.91	0.93
fibroblast of cardiac tissue	3573	0.92	0.91	0.82	0.76	0.00	0.93	0.95	0.93	0.96
hematopoietic stem cell	2971	0.93	0.94	0.95	0.96	0.00	0.95	0.97	0.96	0.97
granulocyte	2676	0.92	0.91	0.90	0.92	0.00	0.92	0.95	0.95	0.96
naive B cell	2627	0.43	0.02	0.75	0.60	0.00	0.88	0.60	0.66	0.72
skeletal muscle satellite cell	2459	0.98	0.97	0.91	0.90	0.00	0.95	0.98	0.97	0.98
endothelial cell of coronary artery	2426	0.74	0.74	0.81	0.70	0.00	0.89	0.91	0.88	0.95
keratinocyte stem cell	2382	0.95	0.94	0.96	0.87	0.00	0.95	0.96	0.95	0.97
myeloid cell	2302	0.59	0.65	0.70	0.67	0.00	0.80	0.79	0.78	0.85
enterocyte of epithelium of large intestine	2279	0.93	0.94	0.95	0.94	0.00	0.93	0.96	0.94	0.96
macrophage	2205	0.39	0.48	0.72	0.63	0.00	0.68	0.61	0.66	0.73
basal cell	1950	0.99	0.98	0.98	0.87	0.00	0.97	0.99	0.99	0.99
bronchial smooth muscle cell	1907	0.94	0.94	0.81	0.75	0.00	0.94	0.97	0.96	0.97
oligodendrocyte	1885	0.99	0.99	0.98	0.99	0.00	0.99	1.00	0.99	0.99
DN4 thymocyte	1596	0.60	0.55	0.68	0.69	0.00	0.93	0.85	0.85	0.88
epithelial cell of large intestine	1526	0.87	0.88	0.88	0.85	0.00	0.89	0.96	0.93	0.94
thymocyte	1465	0.88	0.91	0.80	0.90	0.00	0.94	0.95	0.95	0.96
large intestine goblet cell	1422	0.78	0.82	0.90	0.87	0.00	0.91	0.95	0.93	0.96
intestinal crypt stem cell	1420	0.90	0.91	0.92	0.89	0.00	0.90	0.95	0.92	0.95
mesenchymal stem cell	1255	0.63	0.68	0.65	0.54	0.00	0.91	0.88	0.83	0.91
bladder urothelial cell	1281	0.96	0.94	0.94	0.92	0.00	0.98	0.99	0.99	0.99
type B pancreatic cell	1213	0.96	0.96	0.90	0.96	0.00	0.96	0.98	0.97	0.97
fibroblast	1198	0.55	0.55	0.60	0.52	0.00	0.87	0.91	0.84	0.92
T cell	1201	0.48	0.52	0.61	0.58	0.00	0.68	0.75	0.78	0.74
monocyte	1167	0.66	0.71	0.84	0.71	0.00	0.76	0.87	0.86	0.91
keratinocyte	1090	0.80	0.89	0.91	0.81	0.00	0.85	0.93	0.90	0.92
CD4-positive, alpha-beta T cell	1028	0.56	0.54	0.67	0.59	0.00	0.71	0.70	0.79	0.78
hepatocyte	1050	0.96	0.95	0.95	0.94	0.00	0.95	0.99	0.97	0.98
CD8-positive, alpha-beta T cell	960	0.51	0.50	0.62	0.62	0.00	0.70	0.75	0.78	0.75
promonocyte	914	0.58	0.58	0.92	0.65	0.00	0.85	0.87	0.86	0.92
bladder cell	919	0.98	0.98	0.91	0.76	0.00	0.96	0.99	0.97	0.99
natural killer cell	786	0.72	0.75	0.76	0.77	0.00	0.81	0.88	0.88	0.87
precursor B cell	766	0.83	0.83	0.88	0.83	0.00	0.91	0.97	0.95	0.95
luminal epithelial cell of mammary gland	692	0.96	0.96	0.99	0.93	0.00	0.97	1.00	0.99	0.99
endothelial cell of hepatic sinusoid	559	0.95	0.83	0.90	0.85	0.00	0.90	0.99	0.98	0.99
astrocyte	535	0.94	0.94	0.94	0.95	0.00	0.98	0.99	0.99	0.99
immature B cell	536	0.67	0.51	0.62	0.56	0.00	0.70	0.76	0.82	0.87
pancreatic acinar cell	519	0.92	0.94	0.94	0.94	0.00	0.95	0.99	0.98	0.98
secretory cell	501	0.63	0.30	0.77	0.70	0.00	0.85	0.92	0.90	0.95
pancreatic A cell	456	0.84	0.86	0.87	0.85	0.00	0.92	0.97	0.96	0.92
epidermal cell	429	0.68	0.65	0.77	0.77	0.00	0.72	0.81	0.80	0.81
neuron	441	0.68	0.67	0.72	0.82	0.00	0.85	0.98	0.95	0.96
brain pericyte	442	0.79	0.79	0.82	0.82	0.00	0.92	0.99	0.97	0.94
fibroblast of lung	431	0.96	0.95	0.86	0.89	0.00	0.97	0.99	0.98	0.98
granulocytopoietic cell	447	0.88	0.87	0.92	0.85	0.00	0.80	0.94	0.94	0.95
kidney collecting duct epithelial cell	405	0.71	0.82	0.88	0.81	0.00	0.97	1.00	1.00	0.98
aortic endothelial cell	417	0.20	0.02	0.40	0.43	0.00	0.81	0.54	0.52	0.83
epithelial cell	386	0.39	0.04	0.74	0.59	0.00	0.71	0.68	0.76	0.83
late pro-B cell	370	0.85	0.91	0.94	0.85	0.00	0.92	0.99	0.98	0.98
basal epithelial cell of tracheobronchial tree	365	0.71	0.53	0.78	0.60	0.00	0.89	0.94	0.88	0.85
regular atrial cardiac myocyte	366	0.51	0.57	0.77	0.72	0.00	0.78	0.86	0.88	0.90
epithelial cell of proximal tubule	348	0.64	0.77	0.86	0.80	0.00	0.95	0.99	0.99	0.97
endocardial cell	336	0.97	0.92	0.96	0.86	0.00	0.91	0.97	0.96	0.97
myeloid dendritic cell	331	0.47	0.51	0.84	0.62	0.00	0.96	0.90	0.83	0.88
stromal cell	311	0.47	0.25	0.60	0.51	0.00	0.84	0.78	0.71	0.86
mature alpha-beta T cell	295	0.35	0.22	0.61	0.38	0.00	0.73	0.76	0.84	0.81
cardiac valve cell	287	0.89	0.91	0.81	0.81	0.00	0.95	0.97	0.97	0.95
pancreatic ductal cell	274	0.98	0.95	0.98	0.96	0.00	0.99	1.00	1.00	1.00
oligodendrocyte precursor cell	277	0.93	0.99	0.95	0.97	0.00	0.99	1.00	1.00	1.00
adventitial cell	255	0.00	0.49	0.69	0.31	0.00	0.93	0.88	0.76	0.94
chondrocyte	244	0.85	0.79	0.92	0.82	0.00	0.87	0.97	0.97	0.96
Kupffer cell	233	0.93	0.68	0.90	0.78	0.00	0.77	0.99	0.95	0.97
granulocyte monocyte progenitor cell	229	0.73	0.77	0.86	0.83	0.00	0.74	0.91	0.88	0.89
interneuron	216	0.64	0.65	0.83	0.77	0.00	0.88	0.98	0.95	0.93
myeloid leukocyte	190	0.08	0.05	0.83	0.45	0.00	0.83	0.86	0.89	0.97
classical monocyte	186	0.00	0.30	0.64	0.50	0.00	0.96	0.84	0.80	0.92
mature NK T cell	175	0.37	0.14	0.63	0.37	0.00	0.63	0.90	0.90	0.91
pancreatic D cell	172	0.89	0.89	0.89	0.85	0.00	0.91	0.97	0.95	0.97
brush cell of epithelium proper of large intestine	155	0.80	0.78	0.80	0.87	0.00	0.96	0.99	0.97	0.95
epithelial cell of thymus	145	0.35	0.02	0.58	0.52	0.00	0.76	0.91	0.71	0.95
enteroendocrine cell	151	0.89	0.62	0.74	0.71	0.00	0.92	0.99	0.97	0.97
leukocyte	142	0.00	0.26	0.73	0.54	0.00	0.76	0.57	0.86	0.93
neutrophil	138	0.00	0.05	0.18	0.15	0.00	0.87	0.72	0.72	0.80
kidney collecting duct principal cell	139	0.00	0.79	0.88	0.71	0.00	0.90	0.99	0.96	0.99
vein endothelial cell	137	0.51	0.54	0.75	0.51	0.00	0.72	0.94	0.88	0.90
neuroepithelial stem cell	129	0.30	0.03	0.85	0.69	0.00	0.71	0.90	0.84	0.92
non-classical monocyte	133	0.23	0.35	0.58	0.39	0.00	0.88	0.86	0.77	0.86
regular ventricular cardiac myocyte	131	0.69	0.00	0.85	0.82	0.00	0.85	0.97	0.99	0.99
kidney loop of Henle ascending limb epithelial cell	127	0.66	0.85	0.92	0.71	0.00	0.95	1.00	0.99	0.99
smooth muscle cell of trachea	112	0.24	0.08	0.55	0.45	0.00	0.74	0.86	0.79	0.85
professional antigen presenting cell	112	0.15	0.12	0.51	0.62	0.00	0.82	0.86	0.77	0.92
smooth muscle cell of the pulmonary artery	105	0.00	0.58	0.78	0.47	0.00	0.61	0.92	0.90	0.92
proerythroblast	95	0.00	0.06	0.61	0.41	0.00	0.48	0.90	0.90	0.89
medium spiny neuron	95	0.98	0.89	0.82	0.88	0.00	0.95	1.00	0.99	1.00
smooth muscle cell	90	0.00	0.34	0.63	0.58	0.00	0.81	0.96	0.93	0.94
endothelial cell of lymphatic vessel	91	0.45	0.29	0.92	0.63	0.00	0.69	0.85	0.68	0.82
neural stem cell	85	0.78	0.71	0.84	0.86	0.00	0.92	0.99	0.97	0.98
mesangial cell	83	0.00	0.11	0.63	0.38	0.00	0.59	0.83	0.79	0.91
megakaryocyte-erythroid progenitor cell	71	0.39	0.17	0.83	0.83	0.00	0.61	0.88	0.93	0.91
mucus secreting cell	65	0.60	0.56	0.87	0.86	0.00	0.90	0.94	0.97	0.98
early pro-B cell	65	0.60	0.76	0.82	0.83	0.00	0.77	0.99	0.96	0.96
pancreatic PP cell	65	0.00	0.40	0.60	0.37	0.00	0.93	0.97	0.99	0.80
basophil	61	0.53	0.56	0.80	0.82	0.00	0.58	0.96	0.87	0.87
ciliated columnar cell of tracheobronchial tree	61	0.77	0.87	0.93	0.90	0.00	0.84	0.99	0.92	0.96
dendritic cell	54	0.29	0.34	0.77	0.52	0.00	0.75	0.85	0.79	0.71
ependymal cell	48	0.58	0.76	0.97	0.91	0.00	0.91	1.00	0.99	0.99
Bergmann glial cell	52	0.63	0.42	0.83	0.75	0.00	0.95	0.99	0.99	0.96
pulmonary interstitial fibroblast	46	0.75	0.56	0.74	0.68	0.00	0.81	1.00	0.90	0.97
pancreatic stellate cell	45	0.85	0.43	0.90	0.58	0.00	0.86	0.96	0.93	0.94
regulatory T cell	43	0.00	0.00	0.12	0.23	0.00	0.80	0.90	0.91	0.54
pericyte	35	0.85	0.82	0.72	0.76	0.00	0.88	0.93	0.93	0.92
fibrocyte	36	0.00	0.00	0.39	0.39	0.00	0.45	0.90	0.86	0.86
respiratory basal cell	29	0.00	0.00	0.88	0.26	0.00	0.88	0.94	0.85	0.93
plasma cell	24	0.17	0.00	0.68	0.21	0.00	0.37	0.43	0.33	0.42
club cell	20	0.00	0.00	0.22	0.47	0.00	0.26	0.82	0.53	0.62
kidney interstitial fibroblast	15	0.00	0.00	0.58	0.76	0.00	0.52	1.00	1.00	1.00
lymphoid lineage restricted progenitor cell	11	0.90	0.00	0.90	0.95	0.00	0.39	0.81	0.92	0.95
intermediate monocyte	12	0.00	0.00	0.13	0.00	0.00	0.79	1.00	1.00	0.50
lymphocyte	9	0.00	0.00	0.36	0.00	0.00	0.51	0.90	0.95	0.57
lung macrophage	8	0.00	0.00	0.20	0.20	0.00	0.36	0.89	0.76	0.88
plasmacytoid dendritic cell	6	0.00	0.00	0.00	0.00	0.00	0.46	0.57	0.92	0.50
lung neuroendocrine cell	4	0.00	0.00	0.86	0.33	0.00	0.57	0.80	1.00	1.00

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