data/cell_line_metadata.csv

,cell_name,Cell_ID_DepMap,Cell_ID_Cellosaur,Organ,Driver_Gene_Symbol,Driver_VarZyg,Driver_VarType,Driver_ProtEffect_or_CdnaEffect,Driver_Mech_InferDM,Driver_GeneType_DM
0,A549,ACH-000681,CVCL_0023,Lung,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
1,A549,ACH-000681,CVCL_0023,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
2,A549,ACH-000681,CVCL_0023,Lung,KRAS,Hom,Missense,p.G12S,GoF,Oncogene
3,A549,ACH-000681,CVCL_0023,Lung,SMARCA4,Hom,Frameshift,p.Q729fs,LoF,Suppressor
4,A549,ACH-000681,CVCL_0023,Lung,STK11,Hom,Stopgain,p.Q37*,LoF,Suppressor
5,A549,ACH-000681,CVCL_0023,Lung,ZFHX3,Het,Missense,p.L1473F,,Suppressor
6,HOP-92,ACH-000825,CVCL_1286,Lung,ACVR2A,Het,Missense,p.K133M,LoF,Suppressor
7,HOP-92,ACH-000825,CVCL_1286,Lung,GNAS,Het,Missense,p.V117M,,Oncogene
8,HOP-92,ACH-000825,CVCL_1286,Lung,NF1,Het,Frameshift,p.M799fs,LoF,Suppressor
9,HOP-92,ACH-000825,CVCL_1286,Lung,SOS1,Het,Missense,p.N233Y,GoF,Oncogene
10,HOP-92,ACH-000825,CVCL_1286,Lung,TP53,Hom,Missense,p.R175L,LoF,Suppressor
11,HMVII,ACH-002040,CVCL_1282,Vulva/Vagina,B2M,Hom,Deletion,DEL,LoF,Suppressor
12,HMVII,ACH-002040,CVCL_1282,Vulva/Vagina,BRAF,Het,Missense,p.G469V,GoF,Oncogene
13,HMVII,ACH-002040,CVCL_1282,Vulva/Vagina,BRCA2,Het,Missense,p.M784V,,Suppressor
14,HMVII,ACH-002040,CVCL_1282,Vulva/Vagina,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
15,HMVII,ACH-002040,CVCL_1282,Vulva/Vagina,RB1,Het,Missense,p.L819V,,Suppressor
16,HMVII,ACH-002040,CVCL_1282,Vulva/Vagina,TP53,Het,Missense,p.N268I,LoF,Suppressor
17,Hs 936.T(C1),,CVCL_1034,Skin,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
18,MM485,ACH-001973,CVCL_2610,Skin,APC,Het,Missense,p.P2783S,LoF,Suppressor
19,MM485,ACH-001973,CVCL_2610,Skin,CDKN2A,Hom,Stopgain,p.W59*,LoF,Suppressor
20,MM485,ACH-001973,CVCL_2610,Skin,NRAS,Het,Missense,p.Q61R,GoF,Oncogene
21,MM485,ACH-001973,CVCL_2610,Skin,SMARCB1,Het,Missense,p.W349L,LoF,Suppressor
22,MM485,ACH-001973,CVCL_2610,Skin,TP53,Hom,Stopgain,p.R196*,LoF,Suppressor
23,MM415,ACH-001569,CVCL_2608,Skin,KMT2D,Het,Missense,p.T680P,,Suppressor
24,MM415,ACH-001569,CVCL_2608,Skin,MTOR,Het,Missense,p.L2185F,,Oncogene
25,MM415,ACH-001569,CVCL_2608,Skin,NF1,Het,Stopgain,p.R1276*,LoF,Suppressor
26,MM415,ACH-001569,CVCL_2608,Skin,NRAS,Het,Missense,p.Q61L,GoF,Oncogene
27,MM415,ACH-001569,CVCL_2608,Skin,SMARCB1,Het,Missense,p.T214M,LoF,Suppressor
28,MM415,ACH-001569,CVCL_2608,Skin,TP53,Hom,Missense,p.A347V,,Suppressor
29,MCF-7,ACH-000019,CVCL_0031,Breast,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
30,MCF-7,ACH-000019,CVCL_0031,Breast,GNAS,,Gain,GAIN,GoF,Oncogene
31,MCF-7,ACH-000019,CVCL_0031,Breast,NRAS,,Gain,GAIN,GoF,Oncogene
32,MCF-7,ACH-000019,CVCL_0031,Breast,PIK3CA,Het,Missense,p.E545K,GoF,Oncogene
33,MCF-7,ACH-000019,CVCL_0031,Breast,SMAD3,Het,Splice_site,p.V90F,LoF,Suppressor
34,MCF-7,ACH-000019,CVCL_0031,Breast,WNK2,Het,Missense,p.L312Q,,Suppressor
35,SK-MEL-30,ACH-000810,CVCL_0039,Skin,APC,Het,Missense,p.G1339R,,Suppressor
36,SK-MEL-30,ACH-000810,CVCL_0039,Skin,APC,Het,Stopgain,p.Q1406*,LoF,Suppressor
37,SK-MEL-30,ACH-000810,CVCL_0039,Skin,BRAF,Het,Missense,p.E275K,,Oncogene
38,SK-MEL-30,ACH-000810,CVCL_0039,Skin,CDKN2A,Hom,Missense,p.P63L,LoF,Suppressor
39,SK-MEL-30,ACH-000810,CVCL_0039,Skin,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
40,SK-MEL-30,ACH-000810,CVCL_0039,Skin,TERT,,Promoter,1-124C>T,GoF,Oncogene
41,SK-MEL-30,ACH-000810,CVCL_0039,Skin,TP53,Het,Missense,p.R273H,LoF,Suppressor
42,SK-MEL-30,ACH-000810,CVCL_0039,Skin,TP53,Het,Frameshift,p.T284fs,LoF,Suppressor
43,SW620,ACH-000651,CVCL_0547,Bowel,APC,Hom,Stopgain,p.Q1338*,LoF,Suppressor
44,SW620,ACH-000651,CVCL_0547,Bowel,EGFR,Het,Missense,p.C186S,,Oncogene
45,SW620,ACH-000651,CVCL_0547,Bowel,EP300,Het,Missense,p.P1440L,LoF,Suppressor
46,SW620,ACH-000651,CVCL_0547,Bowel,KRAS,,Gain,GAIN,GoF,Oncogene
47,SW620,ACH-000651,CVCL_0547,Bowel,KRAS,Hom,Missense,p.G12V,GoF,Oncogene
48,SW620,ACH-000651,CVCL_0547,Bowel,MYC,,Gain,GAIN,GoF,Oncogene
49,SW620,ACH-000651,CVCL_0547,Bowel,TP53,Hom,Missense,p.P309S,LoF,Suppressor
50,SW620,ACH-000651,CVCL_0547,Bowel,TP53,Hom,Missense,p.R273H,LoF,Suppressor
51,COLO 205,ACH-001039,CVCL_0218,Bowel,APC,Hom,Frameshift,p.T1556fs,LoF,Suppressor
52,COLO 205,ACH-001039,CVCL_0218,Bowel,BRAF,Het,Missense,p.V600E,GoF,Oncogene
53,COLO 205,ACH-001039,CVCL_0218,Bowel,CTNNB1,Hom,Missense,p.N287S,,Oncogene
54,COLO 205,ACH-001039,CVCL_0218,Bowel,GNAS,Het,Missense,p.S95I,,Oncogene
55,COLO 205,ACH-001039,CVCL_0218,Bowel,MTOR,Het,Missense,p.P1193L,,Oncogene
56,COLO 205,ACH-001039,CVCL_0218,Bowel,PMS2,Het,Missense,p.E504Q,,Suppressor
57,COLO 205,ACH-001039,CVCL_0218,Bowel,TP53,Hom,Frameshift,p.Y103fs,LoF,Suppressor
58,COLO 205,ACH-001039,CVCL_0218,Bowel,TP53,Hom,Frameshift,p.Y107fs,LoF,Suppressor
59,HCC-2998,ACH-001081,CVCL_1266,Bowel,ACVR2A,Het,Stopgain,p.E112*,LoF,Suppressor
60,HCC-2998,ACH-001081,CVCL_1266,Bowel,APC,Het,Missense,p.I2167S,LoF,Suppressor
61,HCC-2998,ACH-001081,CVCL_1266,Bowel,APC,Het,Stopgain,p.L665*,LoF,Suppressor
62,HCC-2998,ACH-001081,CVCL_1266,Bowel,APC,Het,Missense,p.N2720K,,Suppressor
63,HCC-2998,ACH-001081,CVCL_1266,Bowel,APC,Het,Stopgain,p.R1450*,LoF,Suppressor
64,HCC-2998,ACH-001081,CVCL_1266,Bowel,APC,Het,Missense,p.R168I,LoF,Suppressor
65,HCC-2998,ACH-001081,CVCL_1266,Bowel,APC,Het,Missense,p.S1864Y,LoF,Suppressor
66,HCC-2998,ACH-001081,CVCL_1266,Bowel,ARID1A,Het,Stopgain,p.R1772*,LoF,Suppressor
67,HCC-2998,ACH-001081,CVCL_1266,Bowel,ATM,Het,Missense,p.E1133K,,Suppressor
68,HCC-2998,ACH-001081,CVCL_1266,Bowel,ATM,Het,Stopgain,p.E277*,LoF,Suppressor
69,HCC-2998,ACH-001081,CVCL_1266,Bowel,ATM,Het,Missense,p.L1439I,,Suppressor
70,HCC-2998,ACH-001081,CVCL_1266,Bowel,ATM,Het,Stopgain,p.R250*,LoF,Suppressor
71,HCC-2998,ACH-001081,CVCL_1266,Bowel,ATM,Het,Missense,p.R337C,LoF,Suppressor
72,HCC-2998,ACH-001081,CVCL_1266,Bowel,B2M,Het,Stopgain,p.E56*,LoF,Suppressor
73,HCC-2998,ACH-001081,CVCL_1266,Bowel,BRCA2,Het,Missense,p.D1177N,,Suppressor
74,HCC-2998,ACH-001081,CVCL_1266,Bowel,BRCA2,Het,Missense,p.E3342K,,Suppressor
75,HCC-2998,ACH-001081,CVCL_1266,Bowel,BRCA2,Het,Missense,p.K817N,,Suppressor
76,HCC-2998,ACH-001081,CVCL_1266,Bowel,BRCA2,Het,Missense,p.K981N,,Suppressor
77,HCC-2998,ACH-001081,CVCL_1266,Bowel,BRCA2,Het,Missense,p.L2136V,,Suppressor
78,HCC-2998,ACH-001081,CVCL_1266,Bowel,BRCA2,Het,Missense,p.P288S,,Suppressor
79,HCC-2998,ACH-001081,CVCL_1266,Bowel,BRCA2,Het,Missense,p.R2896C,,Suppressor
80,HCC-2998,ACH-001081,CVCL_1266,Bowel,CDKN2A,Het,Missense,p.A36G,LoF,Suppressor
81,HCC-2998,ACH-001081,CVCL_1266,Bowel,EP300,Het,Stopgain,p.E465*,LoF,Suppressor
82,HCC-2998,ACH-001081,CVCL_1266,Bowel,EP300,Het,Missense,p.L1584R,LoF,Suppressor
83,HCC-2998,ACH-001081,CVCL_1266,Bowel,FBXW7,Het,Missense,p.R609W,LoF,Suppressor
84,HCC-2998,ACH-001081,CVCL_1266,Bowel,JAK1,Het,Missense,p.R755Q,,Oncogene
85,HCC-2998,ACH-001081,CVCL_1266,Bowel,KMT2D,Het,Missense,p.T2131P,,Suppressor
86,HCC-2998,ACH-001081,CVCL_1266,Bowel,KRAS,Het,Missense,p.A146T,GoF,Oncogene
87,HCC-2998,ACH-001081,CVCL_1266,Bowel,MSH6,Het,Missense,p.K885N,,Suppressor
88,HCC-2998,ACH-001081,CVCL_1266,Bowel,MTOR,Het,Missense,p.I2500M,GoF,Oncogene
89,HCC-2998,ACH-001081,CVCL_1266,Bowel,MYCL,Het,Missense,p.R357I,,Oncogene
90,HCC-2998,ACH-001081,CVCL_1266,Bowel,NF1,Het,Missense,p.K609N,,Suppressor
91,HCC-2998,ACH-001081,CVCL_1266,Bowel,NF2,Het,Missense,p.K99T,LoF,Suppressor
92,HCC-2998,ACH-001081,CVCL_1266,Bowel,PIK3CB,Het,Missense,p.R149Q,,Oncogene
93,HCC-2998,ACH-001081,CVCL_1266,Bowel,PIK3CB,Het,Missense,p.R562Q,,Oncogene
94,HCC-2998,ACH-001081,CVCL_1266,Bowel,PIK3R1,Het,Stopgain,p.R98*,LoF,Suppressor
95,HCC-2998,ACH-001081,CVCL_1266,Bowel,PIK3R1,Het,Splice_site,,LoF,Suppressor
96,HCC-2998,ACH-001081,CVCL_1266,Bowel,PMS2,Het,Missense,p.A854T,,Suppressor
97,HCC-2998,ACH-001081,CVCL_1266,Bowel,PMS2,Het,Missense,p.D286E,,Suppressor
98,HCC-2998,ACH-001081,CVCL_1266,Bowel,POLE,Het,Missense,p.P286R,LoF,Suppressor
99,HCC-2998,ACH-001081,CVCL_1266,Bowel,PRDM2,Het,Missense,p.L595V,,Suppressor
100,HCC-2998,ACH-001081,CVCL_1266,Bowel,PRDM2,Het,Missense,p.S470Y,,Suppressor
101,HCC-2998,ACH-001081,CVCL_1266,Bowel,PTEN,Het,Missense,p.F341V,LoF,Suppressor
102,HCC-2998,ACH-001081,CVCL_1266,Bowel,PTEN,Het,Missense,p.R130Q,LoF,Suppressor
103,HCC-2998,ACH-001081,CVCL_1266,Bowel,PTEN,Het,Missense,p.Y46C,LoF,Suppressor
104,HCC-2998,ACH-001081,CVCL_1266,Bowel,PTPN11,Het,Missense,p.I54T,,Oncogene
105,HCC-2998,ACH-001081,CVCL_1266,Bowel,RAF1,Het,Missense,p.S257L,GoF,Oncogene
106,HCC-2998,ACH-001081,CVCL_1266,Bowel,RB1,Het,Stopgain,p.E137*,LoF,Suppressor
107,HCC-2998,ACH-001081,CVCL_1266,Bowel,RB1,Het,Missense,p.F473C,LoF,Suppressor
108,HCC-2998,ACH-001081,CVCL_1266,Bowel,RB1,Het,Missense,p.K80N,,Suppressor
109,HCC-2998,ACH-001081,CVCL_1266,Bowel,SMAD2,Het,Missense,p.R321Q,LoF,Suppressor
110,HCC-2998,ACH-001081,CVCL_1266,Bowel,SMAD2,Het,Missense,p.S276L,LoF,Suppressor
111,HCC-2998,ACH-001081,CVCL_1266,Bowel,SMAD3,Het,Missense,p.S222L,LoF,Suppressor
112,HCC-2998,ACH-001081,CVCL_1266,Bowel,SOS1,Het,Missense,p.I736R,,Oncogene
113,HCC-2998,ACH-001081,CVCL_1266,Bowel,TP53,Het,Stopgain,p.R213*,LoF,Suppressor
114,HCC-2998,ACH-001081,CVCL_1266,Bowel,XPO1,Het,Missense,p.E571K,GoF,Oncogene
115,HCC-2998,ACH-001081,CVCL_1266,Bowel,XPO1,Het,Missense,p.R712I,,Oncogene
116,NCI-H1385,ACH-000737,CVCL_1466,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
117,SW1463,ACH-000470,CVCL_1718,Bowel,APC,Hom,Frameshift,p.V452fs,LoF,Suppressor
118,SW1463,ACH-000470,CVCL_1718,Bowel,ARID1A,Het,Missense,p.L2042V,,Suppressor
119,SW1463,ACH-000470,CVCL_1718,Bowel,FBXW7,Het,Missense,p.R399Q,LoF,Suppressor
120,SW1463,ACH-000470,CVCL_1718,Bowel,KRAS,Hom,Missense,p.G12C,GoF,Oncogene
121,SW1463,ACH-000470,CVCL_1718,Bowel,MTOR,Het,Missense,p.A1099G,,Oncogene
122,SW1463,ACH-000470,CVCL_1718,Bowel,RNF43,Het,Missense,p.R223P,,Suppressor
123,SW1463,ACH-000470,CVCL_1718,Bowel,SMAD4,Hom,Missense,p.R265G,LoF,Suppressor
124,SW1463,ACH-000470,CVCL_1718,Bowel,TP53,Hom,Missense,p.R248Q,LoF,Suppressor
125,SW837,ACH-000421,CVCL_1729,Bowel,ACVR2A,Hom,Splice_site,,LoF,Suppressor
126,SW837,ACH-000421,CVCL_1729,Bowel,APC,Het,Stopgain,p.R1450*,LoF,Suppressor
127,SW837,ACH-000421,CVCL_1729,Bowel,APC,Het,Stopgain,p.R213*,LoF,Suppressor
128,SW837,ACH-000421,CVCL_1729,Bowel,ATM,Het,Missense,p.H448R,,Suppressor
129,SW837,ACH-000421,CVCL_1729,Bowel,EGFR,Het,Missense,p.C186S,,Oncogene
130,SW837,ACH-000421,CVCL_1729,Bowel,EGFR,Het,Missense,p.R264G,,Oncogene
131,SW837,ACH-000421,CVCL_1729,Bowel,FBXW7,Hom,Frameshift,p.L323fs,LoF,Suppressor
132,SW837,ACH-000421,CVCL_1729,Bowel,KRAS,Het,Missense,p.G12C,GoF,Oncogene
133,SW837,ACH-000421,CVCL_1729,Bowel,TP53,Hom,Missense,p.R248W,LoF,Suppressor
134,LU65,ACH-000438,CVCL_1392,Lung,CDKN2A,Het,Missense,p.D23P,,Suppressor
135,LU65,ACH-000438,CVCL_1392,Lung,CDKN2A,Hom,Missense,p.H15R,LoF,Suppressor
136,LU65,ACH-000438,CVCL_1392,Lung,EGFR,Het,Missense,p.L858R,,Oncogene
137,LU65,ACH-000438,CVCL_1392,Lung,KRAS,,Gain,GAIN,GoF,Oncogene
138,LU65,ACH-000438,CVCL_1392,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
139,LU65,ACH-000438,CVCL_1392,Lung,RB1,Hom,Stopgain,p.S82*,LoF,Suppressor
140,LU65,ACH-000438,CVCL_1392,Lung,STK11,Hom,Splice_site,,LoF,Suppressor
141,LU65,ACH-000438,CVCL_1392,Lung,TP53,Het,Missense,p.E11Q,,Suppressor
142,LU65,ACH-000438,CVCL_1392,Lung,TP53,Hom,Splice_site,p.T125T,LoF,Suppressor
143,LU65,ACH-000438,CVCL_1392,Lung,WNK2,Hom,Missense,p.V1821M,,Suppressor
144,LU99,ACH-000444,CVCL_3015,Lung,BRCA2,Het,Missense,p.M784V,,Suppressor
145,LU99,ACH-000444,CVCL_3015,Lung,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
146,LU99,ACH-000444,CVCL_3015,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
147,LU99,ACH-000444,CVCL_3015,Lung,EP300,Hom,Frameshift,p.I967fs,LoF,Suppressor
148,LU99,ACH-000444,CVCL_3015,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
149,LU99,ACH-000444,CVCL_3015,Lung,NF2,Hom,Splice_site,,LoF,Suppressor
150,LU99,ACH-000444,CVCL_3015,Lung,PIK3CA,Het,Missense,p.T1025A,GoF,Oncogene
151,LU99,ACH-000444,CVCL_3015,Lung,POLE,Het,Missense,p.D535Y,LoF,Suppressor
152,LU99,ACH-000444,CVCL_3015,Lung,ZFHX3,Hom,Missense,p.E1900A,,Suppressor
153,HT-29,ACH-000552,CVCL_0320,Bowel,APC,Het,Stopgain,p.E853*,LoF,Suppressor
154,HT-29,ACH-000552,CVCL_0320,Bowel,APC,Het,Frameshift,p.T1556fs,LoF,Suppressor
155,HT-29,ACH-000552,CVCL_0320,Bowel,BRAF,Het,Missense,p.V600E,GoF,Oncogene
156,HT-29,ACH-000552,CVCL_0320,Bowel,MYC,,Gain,GAIN,GoF,Oncogene
157,HT-29,ACH-000552,CVCL_0320,Bowel,PIK3CA,Het,Missense,p.P449T,,Oncogene
158,HT-29,ACH-000552,CVCL_0320,Bowel,SMAD4,Hom,Stopgain,p.Q311*,LoF,Suppressor
159,HT-29,ACH-000552,CVCL_0320,Bowel,TP53,Hom,Missense,p.R273H,LoF,Suppressor
160,HT-29,ACH-000552,CVCL_0320,Bowel,ZFHX3,Het,Missense,p.I1217M,,Suppressor
161,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,APC,Het,Missense,p.D1810E,,Suppressor
162,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,ATM,Het,Missense,p.R924W,,Suppressor
163,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,CCND1,,Gain,GAIN,GoF,Oncogene
164,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,ERBB2,,Gain,GAIN,GoF,Oncogene
165,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,KMT2D,Het,Missense,p.Q3904H,,Suppressor
166,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,KRAS,Het,Missense,p.G12C,GoF,Oncogene
167,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,SMARCA4,Het,Missense,p.V1207I,,Suppressor
168,KYSE-410,ACH-000809,CVCL_1352,Esophagus/Stomach,TP53,Hom,Missense,p.R337C,LoF,Suppressor
169,NCI-H358,ACH-000860,CVCL_1559,Lung,ERBB3,Het,Missense,p.R421K,,Oncogene
170,NCI-H358,ACH-000860,CVCL_1559,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
171,NCI-H358,ACH-000860,CVCL_1559,Lung,POLE,Het,Missense,p.V1270F,,Suppressor
172,NCI-H358,ACH-000860,CVCL_1559,Lung,TP53,Hom,Deletion,DEL,LoF,Suppressor
173,NCI-H358,ACH-000860,CVCL_1559,Lung,ZFHX3,Het,Missense,p.R1402C,LoF,Suppressor
174,NCI-H1373,ACH-000845,CVCL_1465,Lung,ATM,Het,Stopgain,p.E2943*,LoF,Suppressor
175,NCI-H1373,ACH-000845,CVCL_1465,Lung,CDKN2A,Hom,Stopgain,p.C21*,LoF,Suppressor
176,NCI-H1373,ACH-000845,CVCL_1465,Lung,CHEK2,Het,Missense,p.D207Y,,Suppressor
177,NCI-H1373,ACH-000845,CVCL_1465,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
178,NCI-H1373,ACH-000845,CVCL_1465,Lung,NF1,Het,Missense,p.I1806M,LoF,Suppressor
179,NCI-H1373,ACH-000845,CVCL_1465,Lung,TP53,Hom,Stopgain,p.E339*,LoF,Suppressor
180,NCI-H1373,ACH-000845,CVCL_1465,Lung,TP53,Hom,Missense,p.P47L,,Suppressor
181,NCI-H1373,ACH-000845,CVCL_1465,Lung,WNK2,Het,Missense,p.G431R,,Suppressor
182,NCI-H1373,ACH-000845,CVCL_1465,Lung,WNK2,Het,Missense,p.P1097S,,Suppressor
183,NCI-H1373,ACH-000845,CVCL_1465,Lung,WNK2,Het,Missense,p.S1520I,,Suppressor
184,Calu-1,ACH-000511,CVCL_0608,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
185,Calu-1,ACH-000511,CVCL_0608,Lung,SETD1B,Het,Missense,p.Q1589P,,Suppressor
186,Calu-1,ACH-000511,CVCL_0608,Lung,TERT,,Promoter,1-124C>T,GoF,Oncogene
187,Calu-1,ACH-000511,CVCL_0608,Lung,TP53,Hom,Deletion,DEL,LoF,Suppressor
188,DLD-1,ACH-001061,CVCL_0248,Bowel,ACVR2A,Hom,Frameshift,p.K437fs,LoF,Suppressor
189,DLD-1,ACH-001061,CVCL_0248,Bowel,APC,Hom,Frameshift,p.I1417fs,LoF,Suppressor
190,DLD-1,ACH-001061,CVCL_0248,Bowel,APC,Het,Missense,p.K993N,,Suppressor
191,DLD-1,ACH-001061,CVCL_0248,Bowel,APC,Het,Stopgain,p.R2166*,LoF,Suppressor
192,DLD-1,ACH-001061,CVCL_0248,Bowel,APC,Het,Missense,p.R727M,LoF,Suppressor
193,DLD-1,ACH-001061,CVCL_0248,Bowel,B2M,Het,Stopgain,p.Y30*,LoF,Suppressor
194,DLD-1,ACH-001061,CVCL_0248,Bowel,B2M,Het,Splice_site,,LoF,Suppressor
195,DLD-1,ACH-001061,CVCL_0248,Bowel,BRCA2,Het,Missense,p.L1053S,,Suppressor
196,DLD-1,ACH-001061,CVCL_0248,Bowel,BRCA2,Het,Frameshift,p.N1784fs,LoF,Suppressor
197,DLD-1,ACH-001061,CVCL_0248,Bowel,BRCA2,Het,Missense,p.R2784Q,LoF,Suppressor
198,DLD-1,ACH-001061,CVCL_0248,Bowel,CHEK2,Het,Missense,p.A247D,LoF,Suppressor
199,DLD-1,ACH-001061,CVCL_0248,Bowel,CHEK2,Het,Missense,p.R145W,LoF,Suppressor
200,DLD-1,ACH-001061,CVCL_0248,Bowel,EP300,Het,Stopgain,p.E1014*,LoF,Suppressor
201,DLD-1,ACH-001061,CVCL_0248,Bowel,EP300,Het,Missense,p.R838C,,Suppressor
202,DLD-1,ACH-001061,CVCL_0248,Bowel,ERBB3,Het,Missense,p.R667H,,Oncogene
203,DLD-1,ACH-001061,CVCL_0248,Bowel,FBXW7,Het,Missense,p.P29S,,Suppressor
204,DLD-1,ACH-001061,CVCL_0248,Bowel,GNAS,Het,Missense,p.K338N,,Oncogene
205,DLD-1,ACH-001061,CVCL_0248,Bowel,KMT2D,Het,Missense,p.E1517D,,Suppressor
206,DLD-1,ACH-001061,CVCL_0248,Bowel,KMT2D,Het,Missense,p.E1667D,,Suppressor
207,DLD-1,ACH-001061,CVCL_0248,Bowel,KMT2D,Het,Missense,p.F5284L,,Suppressor
208,DLD-1,ACH-001061,CVCL_0248,Bowel,KMT2D,Het,Missense,p.L2304M,,Suppressor
209,DLD-1,ACH-001061,CVCL_0248,Bowel,KMT2D,Het,Missense,p.P1931H,,Suppressor
210,DLD-1,ACH-001061,CVCL_0248,Bowel,KRAS,Het,Missense,p.G13D,GoF,Oncogene
211,DLD-1,ACH-001061,CVCL_0248,Bowel,MSH6,Het,Frameshift,p.D1171fs,LoF,Suppressor
212,DLD-1,ACH-001061,CVCL_0248,Bowel,MSH6,Het,Frameshift,p.L290fs,LoF,Suppressor
213,DLD-1,ACH-001061,CVCL_0248,Bowel,MSH6,Het,Missense,p.R1172del,,Suppressor
214,DLD-1,ACH-001061,CVCL_0248,Bowel,MSH6,Het,Missense,p.Y469F,,Suppressor
215,DLD-1,ACH-001061,CVCL_0248,Bowel,NF1,Het,Missense,p.A2596V,,Suppressor
216,DLD-1,ACH-001061,CVCL_0248,Bowel,PIK3CA,Het,Missense,p.D549N,GoF,Oncogene
217,DLD-1,ACH-001061,CVCL_0248,Bowel,PIK3CA,Het,Missense,p.E545K,GoF,Oncogene
218,DLD-1,ACH-001061,CVCL_0248,Bowel,PIK3R1,Het,Missense,p.P312L,,Suppressor
219,DLD-1,ACH-001061,CVCL_0248,Bowel,RNF43,Het,Frameshift,p.G659fs,LoF,Suppressor
220,DLD-1,ACH-001061,CVCL_0248,Bowel,RNF43,Het,Missense,p.L214M,,Suppressor
221,DLD-1,ACH-001061,CVCL_0248,Bowel,SETD1B,Het,Missense,p.D159N,,Suppressor
222,DLD-1,ACH-001061,CVCL_0248,Bowel,SETD1B,Het,Frameshift,p.H8fs,LoF,Suppressor
223,DLD-1,ACH-001061,CVCL_0248,Bowel,SETD1B,Het,Missense,p.Q780H,LoF,Suppressor
224,DLD-1,ACH-001061,CVCL_0248,Bowel,SMARCA4,Het,Missense,p.R885C,LoF,Suppressor
225,DLD-1,ACH-001061,CVCL_0248,Bowel,TGFBR2,Het,Frameshift,p.K128fs,LoF,Suppressor
226,DLD-1,ACH-001061,CVCL_0248,Bowel,TGFBR2,Het,Missense,p.L452P,LoF,Suppressor
227,DLD-1,ACH-001061,CVCL_0248,Bowel,TP53,Het,Missense,p.S241F,LoF,Suppressor
228,DLD-1,ACH-001061,CVCL_0248,Bowel,TP53,Het,Splice_site,,LoF,Suppressor
229,DLD-1,ACH-001061,CVCL_0248,Bowel,ZFHX3,Het,Missense,p.P1707H,,Suppressor
230,DLD-1,ACH-001061,CVCL_0248,Bowel,ZFHX3,Het,Missense,p.P3069T,LoF,Suppressor
231,LS123,ACH-000501,CVCL_1383,Bowel,ACVR2A,Het,Missense,p.R400H,LoF,Suppressor
232,LS123,ACH-000501,CVCL_1383,Bowel,APC,Het,Missense,p.M431I,,Suppressor
233,LS123,ACH-000501,CVCL_1383,Bowel,APC,Het,Stopgain,p.Q625*,LoF,Suppressor
234,LS123,ACH-000501,CVCL_1383,Bowel,APC,Het,Stopgain,p.R1450*,LoF,Suppressor
235,LS123,ACH-000501,CVCL_1383,Bowel,KRAS,Het,Missense,p.G12S,GoF,Oncogene
236,LS123,ACH-000501,CVCL_1383,Bowel,MTOR,Het,Missense,p.A1099G,,Oncogene
237,LS123,ACH-000501,CVCL_1383,Bowel,SMAD4,Hom,Stopgain,p.E234*,LoF,Suppressor
238,LS123,ACH-000501,CVCL_1383,Bowel,TP53,Hom,Missense,p.R175H,LoF,Suppressor
239,Caco-2,ACH-000003,CVCL_0025,Bowel,APC,Hom,Stopgain,p.Q1367*,LoF,Suppressor
240,Caco-2,ACH-000003,CVCL_0025,Bowel,CHEK2,,Deletion,DEL,LoF,Suppressor
241,Caco-2,ACH-000003,CVCL_0025,Bowel,CTNNB1,Het,Missense,p.G245A,,Oncogene
242,Caco-2,ACH-000003,CVCL_0025,Bowel,EP300,,Deletion,DEL,LoF,Suppressor
243,Caco-2,ACH-000003,CVCL_0025,Bowel,NF2,,Deletion,DEL,LoF,Suppressor
244,Caco-2,ACH-000003,CVCL_0025,Bowel,SMAD4,Hom,Missense,p.D351H,,Suppressor
245,Caco-2,ACH-000003,CVCL_0025,Bowel,SMARCB1,,Deletion,DEL,LoF,Suppressor
246,Caco-2,ACH-000003,CVCL_0025,Bowel,TP53,Hom,Stopgain,p.E204*,LoF,Suppressor
247,HCT-8,ACH-001084,CVCL_2478,Bowel,APC,,Frameshift,p.I1417fs,LoF,Suppressor
248,HCT-8,ACH-001084,CVCL_2478,Bowel,APC,,Missense,p.K993N,,Suppressor
249,HCT-8,ACH-001084,CVCL_2478,Bowel,APC,,Stopgain,p.R2166*,LoF,Suppressor
250,HCT-8,ACH-001084,CVCL_2478,Bowel,APC,,Missense,p.R727M,LoF,Suppressor
251,HCT-8,ACH-001084,CVCL_2478,Bowel,CTNNB1,,Missense,p.V79I,,Oncogene
252,HCT-8,ACH-001084,CVCL_2478,Bowel,KRAS,,Missense,p.G13D,GoF,Oncogene
253,HCT-8,ACH-001084,CVCL_2478,Bowel,PIK3CA,,Missense,p.D549N,GoF,Oncogene
254,HCT-8,ACH-001084,CVCL_2478,Bowel,PIK3CA,,Missense,p.E545K,GoF,Oncogene
255,HCT-8,ACH-001084,CVCL_2478,Bowel,SMAD2,,Frameshift,p.P164fs,LoF,Suppressor
256,HCT-8,ACH-001084,CVCL_2478,Bowel,SMAD3,,Missense,p.V244I,,Suppressor
257,SK-CO-1,ACH-000400,CVCL_0626,Bowel,APC,Het,Frameshift,p.F1089fs,LoF,Suppressor
258,SK-CO-1,ACH-000400,CVCL_0626,Bowel,APC,Het,Frameshift,p.P1443fs,LoF,Suppressor
259,SK-CO-1,ACH-000400,CVCL_0626,Bowel,EP300,Het,Missense,p.P842S,,Suppressor
260,SK-CO-1,ACH-000400,CVCL_0626,Bowel,GNAS,Het,Missense,p.R201C,,Oncogene
261,SK-CO-1,ACH-000400,CVCL_0626,Bowel,KRAS,Het,Missense,p.G12V,GoF,Oncogene
262,SK-CO-1,ACH-000400,CVCL_0626,Bowel,SETD1B,Het,Missense,p.Q1589P,,Suppressor
263,SW480,ACH-000842,CVCL_0546,Bowel,APC,Hom,Stopgain,p.Q1338*,LoF,Suppressor
264,SW480,ACH-000842,CVCL_0546,Bowel,ATM,Het,Missense,p.R2461P,LoF,Suppressor
265,SW480,ACH-000842,CVCL_0546,Bowel,KRAS,Hom,Missense,p.G12V,GoF,Oncogene
266,SW480,ACH-000842,CVCL_0546,Bowel,MYC,,Gain,GAIN,GoF,Oncogene
267,SW480,ACH-000842,CVCL_0546,Bowel,TP53,Hom,Missense,p.P309S,LoF,Suppressor
268,SW480,ACH-000842,CVCL_0546,Bowel,TP53,Hom,Missense,p.R273H,LoF,Suppressor
269,SW 1573,ACH-000677,CVCL_1720,Lung,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
270,SW 1573,ACH-000677,CVCL_1720,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
271,SW 1573,ACH-000677,CVCL_1720,Lung,CTNNB1,Het,Missense,p.S33F,GoF,Oncogene
272,SW 1573,ACH-000677,CVCL_1720,Lung,KRAS,Hom,Missense,p.G12C,GoF,Oncogene
273,SW 1573,ACH-000677,CVCL_1720,Lung,PIK3CA,Het,Missense,p.K111E,GoF,Oncogene
274,SW 1573,ACH-000677,CVCL_1720,Lung,PRDM2,Hom,Missense,p.L824Q,,Suppressor
275,SW 1573,ACH-000677,CVCL_1720,Lung,SMAD4,Hom,Deletion,DEL,LoF,Suppressor
276,SW 1573,ACH-000677,CVCL_1720,Lung,SMARCB1,Hom,Splice_site,,LoF,Suppressor
277,HCC1143,ACH-000374,CVCL_1245,Breast,AKT1,,Gain,GAIN,GoF,Oncogene
278,HCC1143,ACH-000374,CVCL_1245,Breast,CCND1,,Gain,GAIN,GoF,Oncogene
279,HCC1143,ACH-000374,CVCL_1245,Breast,FGFR2,Het,Missense,p.R203C,,Oncogene
280,HCC1143,ACH-000374,CVCL_1245,Breast,SMARCA4,Het,Missense,p.R1323H,LoF,Suppressor
281,HCC1143,ACH-000374,CVCL_1245,Breast,TP53,Hom,Missense,p.R248Q,LoF,Suppressor
282,HS-578T,ACH-000148,CVCL_0332,Breast,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
283,HS-578T,ACH-000148,CVCL_0332,Breast,HNF1A,Het,Missense,p.K273E,LoF,Suppressor
284,HS-578T,ACH-000148,CVCL_0332,Breast,HRAS,Het,Missense,p.G12D,GoF,Oncogene
285,HS-578T,ACH-000148,CVCL_0332,Breast,NF1,Het,Missense,p.G2724R,,Suppressor
286,HS-578T,ACH-000148,CVCL_0332,Breast,PIK3R1,Hom,Missense,p.89_90insN,,Suppressor
287,HS-578T,ACH-000148,CVCL_0332,Breast,TP53,Hom,Missense,p.V157F,LoF,Suppressor
288,SW1116,ACH-000489,CVCL_0544,Bowel,APC,Het,Frameshift,p.Q1429fs,LoF,Suppressor
289,SW1116,ACH-000489,CVCL_0544,Bowel,APC,Het,Stopgain,p.Q264*,LoF,Suppressor
290,SW1116,ACH-000489,CVCL_0544,Bowel,FBXW7,Het,Missense,p.H380Y,LoF,Suppressor
291,SW1116,ACH-000489,CVCL_0544,Bowel,KRAS,Het,Missense,p.G12A,GoF,Oncogene
292,SW1116,ACH-000489,CVCL_0544,Bowel,TP53,Hom,Missense,p.A159D,LoF,Suppressor
293,SW1116,ACH-000489,CVCL_0544,Bowel,WNK2,Het,Missense,p.A1048G,,Suppressor
294,SW1116,ACH-000489,CVCL_0544,Bowel,ZFHX3,Het,Missense,p.G918R,,Suppressor
295,LoVo,ACH-000950,CVCL_0399,Bowel,ACVR2A,Hom,Frameshift,p.K437fs,LoF,Suppressor
296,LoVo,ACH-000950,CVCL_0399,Bowel,APC,Het,Frameshift,p.M1431fs,LoF,Suppressor
297,LoVo,ACH-000950,CVCL_0399,Bowel,APC,Het,Stopgain,p.R1114*,LoF,Suppressor
298,LoVo,ACH-000950,CVCL_0399,Bowel,APC,Het,Missense,p.R2816Q,,Suppressor
299,LoVo,ACH-000950,CVCL_0399,Bowel,ARID1A,Het,Frameshift,p.F1924fs,LoF,Suppressor
300,LoVo,ACH-000950,CVCL_0399,Bowel,B2M,Hom,Frameshift,p.L15fs,LoF,Suppressor
301,LoVo,ACH-000950,CVCL_0399,Bowel,CHEK2,Het,Frameshift,p.T389fs,LoF,Suppressor
302,LoVo,ACH-000950,CVCL_0399,Bowel,FBXW7,Het,Missense,p.R425C,LoF,Suppressor
303,LoVo,ACH-000950,CVCL_0399,Bowel,FGFR3,Het,Missense,p.I533V,,Oncogene
304,LoVo,ACH-000950,CVCL_0399,Bowel,HNF1A,Het,Missense,p.V446M,LoF,Suppressor
305,LoVo,ACH-000950,CVCL_0399,Bowel,KMT2D,Het,Frameshift,p.H77fs,LoF,Suppressor
306,LoVo,ACH-000950,CVCL_0399,Bowel,KRAS,Het,Missense,p.G13D,GoF,Oncogene
307,LoVo,ACH-000950,CVCL_0399,Bowel,NF1,Het,Missense,p.R1674Q,,Suppressor
308,LoVo,ACH-000950,CVCL_0399,Bowel,PIK3CB,Het,Missense,p.E1051K,,Oncogene
309,LoVo,ACH-000950,CVCL_0399,Bowel,PRDM2,Het,Missense,p.S1618G,,Suppressor
310,LoVo,ACH-000950,CVCL_0399,Bowel,PRDM2,Het,Frameshift,p.V1490fs,LoF,Suppressor
311,LoVo,ACH-000950,CVCL_0399,Bowel,RAF1,Het,Missense,p.V98A,,Oncogene
312,LoVo,ACH-000950,CVCL_0399,Bowel,SETD1B,Het,Frameshift,p.H8fs,LoF,Suppressor
313,LoVo,ACH-000950,CVCL_0399,Bowel,SETD1B,Het,Missense,p.V1447I,,Suppressor
314,LoVo,ACH-000950,CVCL_0399,Bowel,SMAD2,Het,Missense,p.A292V,LoF,Suppressor
315,LoVo,ACH-000950,CVCL_0399,Bowel,TGFBR2,Hom,Frameshift,p.K128fs,LoF,Suppressor
316,LoVo,ACH-000950,CVCL_0399,Bowel,WNK2,Het,Missense,p.R2073C,,Suppressor
317,LoVo,ACH-000950,CVCL_0399,Bowel,WNK2,Het,Missense,p.V1544A,,Suppressor
318,SW948,ACH-000680,CVCL_0632,Bowel,APC,Het,Stopgain,p.Q1429*,LoF,Suppressor
319,SW948,ACH-000680,CVCL_0632,Bowel,APC,Het,Stopgain,p.R1114*,LoF,Suppressor
320,SW948,ACH-000680,CVCL_0632,Bowel,ARID1A,Het,Missense,p.G701A,,Suppressor
321,SW948,ACH-000680,CVCL_0632,Bowel,ATM,Het,Stopgain,p.Q2210*,LoF,Suppressor
322,SW948,ACH-000680,CVCL_0632,Bowel,EP300,Het,Splice_site,,LoF,Suppressor
323,SW948,ACH-000680,CVCL_0632,Bowel,KMT2D,Het,Missense,p.N2030H,,Suppressor
324,SW948,ACH-000680,CVCL_0632,Bowel,KMT2D,Het,Missense,p.R5120C,LoF,Suppressor
325,SW948,ACH-000680,CVCL_0632,Bowel,KRAS,Het,Missense,p.Q61L,GoF,Oncogene
326,SW948,ACH-000680,CVCL_0632,Bowel,PIK3CA,Hom,Missense,p.E542K,GoF,Oncogene
327,SW948,ACH-000680,CVCL_0632,Bowel,SMAD4,Hom,Missense,p.D441Y,LoF,Suppressor
328,SW948,ACH-000680,CVCL_0632,Bowel,TP53,Hom,Frameshift,p.T118fs,LoF,Suppressor
329,LS 174T,,CVCL_1384,Bowel,CTNNB1,Hom,Missense,p.S45F,GoF,Oncogene
330,LS 174T,,CVCL_1384,Bowel,KRAS,Het,Missense,p.G12D,GoF,Oncogene
331,LS 174T,,CVCL_1384,Bowel,PIK3CA,,Missense,p.H1047R,GoF,Oncogene
332,SW1417,ACH-000236,CVCL_1717,Bowel,APC,Hom,Stopgain,p.R1450*,LoF,Suppressor
333,SW1417,ACH-000236,CVCL_1717,Bowel,BRAF,Het,Missense,p.V600E,GoF,Oncogene
334,SW1417,ACH-000236,CVCL_1717,Bowel,PIK3R1,Hom,Deletion,DEL,LoF,Suppressor
335,SW1417,ACH-000236,CVCL_1717,Bowel,TP53,Hom,Frameshift,p.C238fs,LoF,Suppressor
336,RKO,ACH-000943,CVCL_0504,Bowel,ACVR2A,Het,Frameshift,p.K437fs,LoF,Suppressor
337,RKO,ACH-000943,CVCL_0504,Bowel,ARID1A,Het,Frameshift,p.D1633fs,LoF,Suppressor
338,RKO,ACH-000943,CVCL_0504,Bowel,ARID1A,Het,Frameshift,p.P1115fs,LoF,Suppressor
339,RKO,ACH-000943,CVCL_0504,Bowel,B2M,Het,Stopgain,p.R117*,LoF,Suppressor
340,RKO,ACH-000943,CVCL_0504,Bowel,BRAF,Het,Missense,p.V600E,GoF,Oncogene
341,RKO,ACH-000943,CVCL_0504,Bowel,BRCA2,Het,Frameshift,p.N1784fs,LoF,Suppressor
342,RKO,ACH-000943,CVCL_0504,Bowel,EP300,Het,Frameshift,p.K292fs,LoF,Suppressor
343,RKO,ACH-000943,CVCL_0504,Bowel,EP300,Het,Frameshift,p.M1470fs,LoF,Suppressor
344,RKO,ACH-000943,CVCL_0504,Bowel,HNF1A,Het,Frameshift,p.P379fs,LoF,Suppressor
345,RKO,ACH-000943,CVCL_0504,Bowel,KMT2D,Het,Frameshift,p.G1960fs,LoF,Suppressor
346,RKO,ACH-000943,CVCL_0504,Bowel,KMT2D,Het,Stopgain,p.G3465*,LoF,Suppressor
347,RKO,ACH-000943,CVCL_0504,Bowel,KMT2D,Het,Missense,p.L1600P,LoF,Suppressor
348,RKO,ACH-000943,CVCL_0504,Bowel,KMT2D,Het,Missense,p.L5056P,LoF,Suppressor
349,RKO,ACH-000943,CVCL_0504,Bowel,KMT2D,Het,Frameshift,p.P2550fs,LoF,Suppressor
350,RKO,ACH-000943,CVCL_0504,Bowel,MSH6,Het,Frameshift,p.Y1066fs,LoF,Suppressor
351,RKO,ACH-000943,CVCL_0504,Bowel,NF1,Het,Frameshift,p.N2320fs,LoF,Suppressor
352,RKO,ACH-000943,CVCL_0504,Bowel,NF1,Het,Missense,p.V2184A,LoF,Suppressor
353,RKO,ACH-000943,CVCL_0504,Bowel,NF1,Het,Frameshift,p.Y628fs,LoF,Suppressor
354,RKO,ACH-000943,CVCL_0504,Bowel,NF2,Het,Frameshift,p.P275fs,LoF,Suppressor
355,RKO,ACH-000943,CVCL_0504,Bowel,PIK3CA,Het,Missense,p.H1047R,GoF,Oncogene
356,RKO,ACH-000943,CVCL_0504,Bowel,POLE,Het,Missense,p.K995E,,Suppressor
357,RKO,ACH-000943,CVCL_0504,Bowel,PRDM2,Het,Missense,p.S876G,,Suppressor
358,RKO,ACH-000943,CVCL_0504,Bowel,RNF43,Hom,Frameshift,p.G659fs,LoF,Suppressor
359,RKO,ACH-000943,CVCL_0504,Bowel,RNF43,Het,Missense,p.H549N,,Suppressor
360,RKO,ACH-000943,CVCL_0504,Bowel,SETD1B,Het,Frameshift,p.H8fs,LoF,Suppressor
361,RKO,ACH-000943,CVCL_0504,Bowel,SETD1B,Het,Missense,p.T1700A,LoF,Suppressor
362,RKO,ACH-000943,CVCL_0504,Bowel,SMAD3,Het,Missense,p.A13T,,Suppressor
363,RKO,ACH-000943,CVCL_0504,Bowel,TGFBR2,Het,Frameshift,p.K128fs,LoF,Suppressor
364,RKO,ACH-000943,CVCL_0504,Bowel,TGFBR2,Het,Missense,p.L452P,LoF,Suppressor
365,RKO,ACH-000943,CVCL_0504,Bowel,ZFHX3,Het,Frameshift,p.F1596fs,LoF,Suppressor
366,RKO,ACH-000943,CVCL_0504,Bowel,ZFHX3,Het,Missense,p.S112N,,Suppressor
367,T84,ACH-000381,CVCL_0555,Bowel,APC,Hom,Frameshift,p.L1488fs,LoF,Suppressor
368,T84,ACH-000381,CVCL_0555,Bowel,KRAS,Het,Missense,p.G13D,GoF,Oncogene
369,T84,ACH-000381,CVCL_0555,Bowel,PIK3CA,Het,Missense,p.E542K,GoF,Oncogene
370,T84,ACH-000381,CVCL_0555,Bowel,SMAD4,Hom,Missense,p.K244N,LoF,Suppressor
371,T84,ACH-000381,CVCL_0555,Bowel,TP53,Hom,Splice_site,,LoF,Suppressor
372,T84,ACH-000381,CVCL_0555,Bowel,ZFHX3,Het,Missense,p.A3398P,,Suppressor
373,SHP-77,ACH-000790,CVCL_1693,Lung,ABL1,Het,Missense,p.V1128E,,Oncogene
374,SHP-77,ACH-000790,CVCL_1693,Lung,ACVR2A,Hom,Missense,p.L147R,LoF,Suppressor
375,SHP-77,ACH-000790,CVCL_1693,Lung,ARID1A,Het,Missense,p.P253S,,Suppressor
376,SHP-77,ACH-000790,CVCL_1693,Lung,EGFR,Het,Missense,p.Q656R,,Oncogene
377,SHP-77,ACH-000790,CVCL_1693,Lung,KMT2D,Hom,Missense,p.Q3950R,,Suppressor
378,SHP-77,ACH-000790,CVCL_1693,Lung,KRAS,Hom,Missense,p.G12V,GoF,Oncogene
379,SHP-77,ACH-000790,CVCL_1693,Lung,RAC1,Het,Missense,p.Y32C,,Oncogene
380,SHP-77,ACH-000790,CVCL_1693,Lung,SETD1B,Het,Missense,p.T482M,,Suppressor
381,SHP-77,ACH-000790,CVCL_1693,Lung,TP53,Hom,Missense,p.C176W,LoF,Suppressor
382,SW 900,ACH-000669,CVCL_1731,Lung,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
383,SW 900,ACH-000669,CVCL_1731,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
384,SW 900,ACH-000669,CVCL_1731,Lung,KMT2D,Hom,Stopgain,p.K5522*,LoF,Suppressor
385,SW 900,ACH-000669,CVCL_1731,Lung,KRAS,Het,Missense,p.G12V,GoF,Oncogene
386,SW 900,ACH-000669,CVCL_1731,Lung,SMAD3,Hom,Missense,p.K334E,LoF,Suppressor
387,SW 900,ACH-000669,CVCL_1731,Lung,TP53,Hom,Stopgain,p.Q167*,LoF,Suppressor
388,MIA PaCa-2,ACH-000601,CVCL_0428,Pancreas,ARID1A,Het,Missense,p.P1723L,,Suppressor
389,MIA PaCa-2,ACH-000601,CVCL_0428,Pancreas,ARID1A,Hom,Stopgain,p.Q321*,LoF,Suppressor
390,MIA PaCa-2,ACH-000601,CVCL_0428,Pancreas,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
391,MIA PaCa-2,ACH-000601,CVCL_0428,Pancreas,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
392,MIA PaCa-2,ACH-000601,CVCL_0428,Pancreas,KRAS,Hom,Missense,p.G12C,GoF,Oncogene
393,MIA PaCa-2,ACH-000601,CVCL_0428,Pancreas,TP53,Hom,Missense,p.R248W,LoF,Suppressor
394,HCT15,ACH-000997,CVCL_0292,Bowel,ACVR2A,Hom,Frameshift,p.K437fs,LoF,Suppressor
395,HCT15,ACH-000997,CVCL_0292,Bowel,APC,Het,Missense,p.E2550Q,,Suppressor
396,HCT15,ACH-000997,CVCL_0292,Bowel,APC,Hom,Frameshift,p.I1417fs,LoF,Suppressor
397,HCT15,ACH-000997,CVCL_0292,Bowel,APC,Het,Missense,p.I1779M,,Suppressor
398,HCT15,ACH-000997,CVCL_0292,Bowel,APC,Het,Missense,p.K1561N,,Suppressor
399,HCT15,ACH-000997,CVCL_0292,Bowel,APC,Het,Missense,p.K993N,,Suppressor
400,HCT15,ACH-000997,CVCL_0292,Bowel,APC,Het,Stopgain,p.R2166*,LoF,Suppressor
401,HCT15,ACH-000997,CVCL_0292,Bowel,APC,Het,Missense,p.R727M,LoF,Suppressor
402,HCT15,ACH-000997,CVCL_0292,Bowel,ARID1A,Het,Missense,p.R270H,,Suppressor
403,HCT15,ACH-000997,CVCL_0292,Bowel,ATM,Het,Missense,p.E586D,,Suppressor
404,HCT15,ACH-000997,CVCL_0292,Bowel,B2M,Het,Stopgain,p.Y30*,LoF,Suppressor
405,HCT15,ACH-000997,CVCL_0292,Bowel,B2M,Het,Splice_site,,LoF,Suppressor
406,HCT15,ACH-000997,CVCL_0292,Bowel,BRCA2,Het,Missense,p.A487V,,Suppressor
407,HCT15,ACH-000997,CVCL_0292,Bowel,BRCA2,Het,Frameshift,p.N1784fs,LoF,Suppressor
408,HCT15,ACH-000997,CVCL_0292,Bowel,BRCA2,Het,Missense,p.R2784Q,LoF,Suppressor
409,HCT15,ACH-000997,CVCL_0292,Bowel,CHEK2,Het,Missense,p.A247D,LoF,Suppressor
410,HCT15,ACH-000997,CVCL_0292,Bowel,CHEK2,Het,Missense,p.R145W,LoF,Suppressor
411,HCT15,ACH-000997,CVCL_0292,Bowel,EP300,Hom,Stopgain,p.E1014*,LoF,Suppressor
412,HCT15,ACH-000997,CVCL_0292,Bowel,ERBB3,Het,Missense,p.R667H,,Oncogene
413,HCT15,ACH-000997,CVCL_0292,Bowel,GNAS,Het,Missense,p.K338N,,Oncogene
414,HCT15,ACH-000997,CVCL_0292,Bowel,KMT2D,Het,Missense,p.E1517D,,Suppressor
415,HCT15,ACH-000997,CVCL_0292,Bowel,KMT2D,Het,Missense,p.P1152H,,Suppressor
416,HCT15,ACH-000997,CVCL_0292,Bowel,KMT2D,Het,Missense,p.P1931H,,Suppressor
417,HCT15,ACH-000997,CVCL_0292,Bowel,KRAS,Het,Missense,p.G13D,GoF,Oncogene
418,HCT15,ACH-000997,CVCL_0292,Bowel,MSH6,Het,Frameshift,p.D1171fs,LoF,Suppressor
419,HCT15,ACH-000997,CVCL_0292,Bowel,MSH6,Het,Frameshift,p.L290fs,LoF,Suppressor
420,HCT15,ACH-000997,CVCL_0292,Bowel,MSH6,Het,Missense,p.R1172del,,Suppressor
421,HCT15,ACH-000997,CVCL_0292,Bowel,MSH6,Het,Missense,p.T1189I,LoF,Suppressor
422,HCT15,ACH-000997,CVCL_0292,Bowel,NF1,Het,Missense,p.A2596V,,Suppressor
423,HCT15,ACH-000997,CVCL_0292,Bowel,NF1,Het,Missense,p.A74D,,Suppressor
424,HCT15,ACH-000997,CVCL_0292,Bowel,NF1,Het,Missense,p.P2456S,,Suppressor
425,HCT15,ACH-000997,CVCL_0292,Bowel,PIK3CA,Het,Missense,p.D549N,GoF,Oncogene
426,HCT15,ACH-000997,CVCL_0292,Bowel,PIK3CA,Het,Missense,p.E545K,GoF,Oncogene
427,HCT15,ACH-000997,CVCL_0292,Bowel,PIK3R1,Het,Missense,p.P312L,,Suppressor
428,HCT15,ACH-000997,CVCL_0292,Bowel,POLE,Het,Missense,p.A1375V,,Suppressor
429,HCT15,ACH-000997,CVCL_0292,Bowel,PRDM2,Het,Stopgain,p.E1259*,LoF,Suppressor
430,HCT15,ACH-000997,CVCL_0292,Bowel,PRDM2,Het,Stopgain,p.Q1699*,LoF,Suppressor
431,HCT15,ACH-000997,CVCL_0292,Bowel,RNF43,Het,Frameshift,p.G659fs,LoF,Suppressor
432,HCT15,ACH-000997,CVCL_0292,Bowel,RNF43,Het,Missense,p.L214M,,Suppressor
433,HCT15,ACH-000997,CVCL_0292,Bowel,SETD1B,Het,Missense,p.D159N,,Suppressor
434,HCT15,ACH-000997,CVCL_0292,Bowel,SETD1B,Het,Missense,p.Q780H,LoF,Suppressor
435,HCT15,ACH-000997,CVCL_0292,Bowel,SMARCA4,Het,Missense,p.R885C,LoF,Suppressor
436,HCT15,ACH-000997,CVCL_0292,Bowel,TGFBR2,Het,Missense,p.L452P,LoF,Suppressor
437,HCT15,ACH-000997,CVCL_0292,Bowel,TP53,Het,Missense,p.S241F,LoF,Suppressor
438,HCT15,ACH-000997,CVCL_0292,Bowel,TP53,Het,Splice_site,,LoF,Suppressor
439,HCT15,ACH-000997,CVCL_0292,Bowel,WNK2,Het,Missense,p.V1971M,,Suppressor
440,HCT15,ACH-000997,CVCL_0292,Bowel,ZFHX3,Het,Frameshift,p.E763fs,LoF,Suppressor
441,HCT15,ACH-000997,CVCL_0292,Bowel,ZFHX3,Het,Missense,p.P1707H,,Suppressor
442,HCT15,ACH-000997,CVCL_0292,Bowel,ZFHX3,Het,Missense,p.P3069T,LoF,Suppressor
443,HCT15,ACH-000997,CVCL_0292,Bowel,ZFHX3,Het,Missense,p.R1402C,LoF,Suppressor
444,HCT15,ACH-000997,CVCL_0292,Bowel,ZFHX3,Het,Missense,p.S1180N,,Suppressor
445,CFPAC-1,ACH-000138,CVCL_1119,Pancreas,KRAS,Het,Missense,p.G12V,GoF,Oncogene
446,CFPAC-1,ACH-000138,CVCL_1119,Pancreas,SMAD4,Hom,Deletion,DEL,LoF,Suppressor
447,CFPAC-1,ACH-000138,CVCL_1119,Pancreas,TP53,Hom,Missense,p.C242R,LoF,Suppressor
448,AsPC-1,ACH-000222,CVCL_0152,Pancreas,CDKN2A,Het,Frameshift,p.L27fs,LoF,Suppressor
449,AsPC-1,ACH-000222,CVCL_0152,Pancreas,FBXW7,Het,Missense,p.R385C,LoF,Suppressor
450,AsPC-1,ACH-000222,CVCL_0152,Pancreas,KRAS,Hom,Missense,p.G12D,GoF,Oncogene
451,AsPC-1,ACH-000222,CVCL_0152,Pancreas,RNF43,Hom,Stopgain,p.S720*,LoF,Suppressor
452,AsPC-1,ACH-000222,CVCL_0152,Pancreas,SMAD4,Hom,Missense,p.R100T,LoF,Suppressor
453,AsPC-1,ACH-000222,CVCL_0152,Pancreas,TP53,Hom,Frameshift,p.C135fs,LoF,Suppressor
454,Panc 02.13,ACH-000031,CVCL_1634,Pancreas,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
455,Panc 02.13,ACH-000031,CVCL_1634,Pancreas,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
456,Panc 02.13,ACH-000031,CVCL_1634,Pancreas,KRAS,Het,Missense,p.Q61R,GoF,Oncogene
457,Panc 02.13,ACH-000031,CVCL_1634,Pancreas,SMARCA4,Het,Missense,p.T910M,LoF,Suppressor
458,Panc 02.13,ACH-000031,CVCL_1634,Pancreas,TP53,Hom,Missense,p.R273C,LoF,Suppressor
459,Hs 766T,ACH-000178,CVCL_0334,Pancreas,ARID1A,Het,Stopgain,p.Q538*,LoF,Suppressor
460,Hs 766T,ACH-000178,CVCL_0334,Pancreas,CDKN2A,Hom,Splice_site,,LoF,Suppressor
461,Hs 766T,ACH-000178,CVCL_0334,Pancreas,KRAS,Hom,Missense,p.Q61H,GoF,Oncogene
462,Hs 766T,ACH-000178,CVCL_0334,Pancreas,SMAD4,Hom,Deletion,DEL,LoF,Suppressor
463,BxPC-3,ACH-000535,CVCL_0186,Pancreas,BRAF,Het,Missense,p.V487_492NA,,Oncogene
464,BxPC-3,ACH-000535,CVCL_0186,Pancreas,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
465,BxPC-3,ACH-000535,CVCL_0186,Pancreas,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
466,BxPC-3,ACH-000535,CVCL_0186,Pancreas,EP300,Het,Stopgain,p.R397*,LoF,Suppressor
467,BxPC-3,ACH-000535,CVCL_0186,Pancreas,RNF43,Hom,Missense,p.S495Y,,Suppressor
468,BxPC-3,ACH-000535,CVCL_0186,Pancreas,SMAD4,Hom,Deletion,DEL,LoF,Suppressor
469,BxPC-3,ACH-000535,CVCL_0186,Pancreas,SMARCB1,Hom,Deletion,DEL,LoF,Suppressor
470,BxPC-3,ACH-000535,CVCL_0186,Pancreas,TP53,Hom,Missense,p.Y220C,LoF,Suppressor
471,PANC-1,ACH-000164,CVCL_0480,Pancreas,AKT2,,Gain,GAIN,GoF,Oncogene
472,PANC-1,ACH-000164,CVCL_0480,Pancreas,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
473,PANC-1,ACH-000164,CVCL_0480,Pancreas,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
474,PANC-1,ACH-000164,CVCL_0480,Pancreas,KRAS,Het,Missense,p.G12D,GoF,Oncogene
475,PANC-1,ACH-000164,CVCL_0480,Pancreas,TP53,Hom,Missense,p.R273H,LoF,Suppressor
476,KLE,ACH-000293,CVCL_1329,Uterus,AKT2,,Gain,GAIN,GoF,Oncogene
477,KLE,ACH-000293,CVCL_1329,Uterus,CCNE1,,Gain,GAIN,GoF,Oncogene
478,KLE,ACH-000293,CVCL_1329,Uterus,FBXW7,Het,Missense,p.R399Q,LoF,Suppressor
479,KLE,ACH-000293,CVCL_1329,Uterus,KRAS,,Gain,GAIN,GoF,Oncogene
480,KLE,ACH-000293,CVCL_1329,Uterus,TP53,Hom,Missense,p.R175H,LoF,Suppressor
481,BT-474,ACH-000927,CVCL_0179,Breast,ACVR2A,Het,Missense,p.S17F,,Suppressor
482,BT-474,ACH-000927,CVCL_0179,Breast,ATM,Het,Missense,p.E2468K,LoF,Suppressor
483,BT-474,ACH-000927,CVCL_0179,Breast,BRCA2,Het,Stopgain,p.S3094*,LoF,Suppressor
484,BT-474,ACH-000927,CVCL_0179,Breast,ERBB2,,Gain,GAIN,GoF,Oncogene
485,BT-474,ACH-000927,CVCL_0179,Breast,HNF1A,Het,Stopgain,p.Q495*,LoF,Suppressor
486,BT-474,ACH-000927,CVCL_0179,Breast,KMT2D,Het,Missense,p.E1623K,,Suppressor
487,BT-474,ACH-000927,CVCL_0179,Breast,LASP1,,Gain,GAIN,GoF,Oncogene
488,BT-474,ACH-000927,CVCL_0179,Breast,MAPK1,Het,Missense,p.H61Q,,Oncogene
489,BT-474,ACH-000927,CVCL_0179,Breast,PIK3CA,Het,Missense,p.K111N,GoF,Oncogene
490,BT-474,ACH-000927,CVCL_0179,Breast,TGFBR2,Het,Missense,p.M36I,,Suppressor
491,BT-474,ACH-000927,CVCL_0179,Breast,TP53,Hom,Missense,p.E285K,LoF,Suppressor
492,BT-474,ACH-000927,CVCL_0179,Breast,WNK2,Het,Missense,p.E398Q,,Suppressor
493,SW48,ACH-000958,CVCL_1724,Bowel,ACVR2A,Hom,Frameshift,p.K437fs,LoF,Suppressor
494,SW48,ACH-000958,CVCL_1724,Bowel,APC,Het,Missense,p.R2714C,,Suppressor
495,SW48,ACH-000958,CVCL_1724,Bowel,ARID1A,Het,Frameshift,p.A339fs,LoF,Suppressor
496,SW48,ACH-000958,CVCL_1724,Bowel,B2M,Het,Stopgain,p.Q22*,LoF,Suppressor
497,SW48,ACH-000958,CVCL_1724,Bowel,B2M,Het,Frameshift,p.V69fs,LoF,Suppressor
498,SW48,ACH-000958,CVCL_1724,Bowel,BRCA2,Het,Frameshift,p.K1691fs,LoF,Suppressor
499,SW48,ACH-000958,CVCL_1724,Bowel,BRCA2,Het,Frameshift,p.N1784fs,LoF,Suppressor
500,SW48,ACH-000958,CVCL_1724,Bowel,CTNNB1,Het,Missense,p.S33Y,GoF,Oncogene
501,SW48,ACH-000958,CVCL_1724,Bowel,EGFR,Het,Missense,p.G674S,GoF,Oncogene
502,SW48,ACH-000958,CVCL_1724,Bowel,EP300,Het,Frameshift,p.M1470fs,LoF,Suppressor
503,SW48,ACH-000958,CVCL_1724,Bowel,EP300,Het,Missense,p.T594M,LoF,Suppressor
504,SW48,ACH-000958,CVCL_1724,Bowel,FBXW7,Het,Frameshift,p.S588fs,LoF,Suppressor
505,SW48,ACH-000958,CVCL_1724,Bowel,KMT2D,Het,Stopgain,p.R4904*,LoF,Suppressor
506,SW48,ACH-000958,CVCL_1724,Bowel,KMT2D,Het,Frameshift,p.R755fs,LoF,Suppressor
507,SW48,ACH-000958,CVCL_1724,Bowel,MAP2K1,Het,Missense,p.D175G,,Oncogene
508,SW48,ACH-000958,CVCL_1724,Bowel,MAP2K1,Het,Missense,p.Q56P,GoF,Oncogene
509,SW48,ACH-000958,CVCL_1724,Bowel,PIK3CA,Het,Missense,p.G914R,GoF,Oncogene
510,SW48,ACH-000958,CVCL_1724,Bowel,RNF43,Het,Frameshift,p.G659fs,LoF,Suppressor
511,SW48,ACH-000958,CVCL_1724,Bowel,RNF43,Het,Frameshift,p.V299fs,LoF,Suppressor
512,SW48,ACH-000958,CVCL_1724,Bowel,SETD1B,Hom,Frameshift,p.H8fs,LoF,Suppressor
513,SW48,ACH-000958,CVCL_1724,Bowel,SMARCA4,Het,Missense,p.A703V,,Suppressor
514,SW48,ACH-000958,CVCL_1724,Bowel,TGFBR2,Hom,Frameshift,p.K128fs,LoF,Suppressor
515,SW48,ACH-000958,CVCL_1724,Bowel,ZFHX3,Het,Frameshift,p.A3407fs,LoF,Suppressor
516,LS411N,ACH-000985,CVCL_1385,Bowel,ACVR2A,Hom,Frameshift,p.K437fs,LoF,Suppressor
517,LS411N,ACH-000985,CVCL_1385,Bowel,APC,Het,Stopgain,p.Q789*,LoF,Suppressor
518,LS411N,ACH-000985,CVCL_1385,Bowel,APC,Het,Frameshift,p.T1556fs,LoF,Suppressor
519,LS411N,ACH-000985,CVCL_1385,Bowel,ARID1A,Het,Frameshift,p.P1326fs,LoF,Suppressor
520,LS411N,ACH-000985,CVCL_1385,Bowel,BRAF,Het,Missense,p.V600E,GoF,Oncogene
521,LS411N,ACH-000985,CVCL_1385,Bowel,BRCA2,Het,Missense,p.E3111K,LoF,Suppressor
522,LS411N,ACH-000985,CVCL_1385,Bowel,CHEK2,Het,Missense,p.P85H,,Suppressor
523,LS411N,ACH-000985,CVCL_1385,Bowel,EP300,Het,Frameshift,p.H2324fs,LoF,Suppressor
524,LS411N,ACH-000985,CVCL_1385,Bowel,ERBB2,Het,Missense,p.E744K,,Oncogene
525,LS411N,ACH-000985,CVCL_1385,Bowel,FBXW7,Het,Missense,p.R425H,LoF,Suppressor
526,LS411N,ACH-000985,CVCL_1385,Bowel,GNAS,Het,Missense,p.R160C,,Oncogene
527,LS411N,ACH-000985,CVCL_1385,Bowel,GNAS,Het,Missense,p.R356C,,Oncogene
528,LS411N,ACH-000985,CVCL_1385,Bowel,HNF1A,Het,Missense,p.L408I,LoF,Suppressor
529,LS411N,ACH-000985,CVCL_1385,Bowel,KMT2D,Het,Missense,p.E1018D,,Suppressor
530,LS411N,ACH-000985,CVCL_1385,Bowel,KMT2D,Het,Missense,p.G4437V,LoF,Suppressor
531,LS411N,ACH-000985,CVCL_1385,Bowel,KMT2D,Het,Frameshift,p.P853fs,LoF,Suppressor
532,LS411N,ACH-000985,CVCL_1385,Bowel,MAPK3,Het,Missense,p.S172C,,Oncogene
533,LS411N,ACH-000985,CVCL_1385,Bowel,MET,Het,Missense,p.T86I,,Oncogene
534,LS411N,ACH-000985,CVCL_1385,Bowel,NF1,Het,Missense,p.T2784I,,Suppressor
535,LS411N,ACH-000985,CVCL_1385,Bowel,PTEN,Het,Frameshift,p.C105fs,LoF,Suppressor
536,LS411N,ACH-000985,CVCL_1385,Bowel,PTEN,Het,Frameshift,p.K164fs,LoF,Suppressor
537,LS411N,ACH-000985,CVCL_1385,Bowel,RNF43,Het,Frameshift,p.G659fs,LoF,Suppressor
538,LS411N,ACH-000985,CVCL_1385,Bowel,SETD1B,Hom,Frameshift,p.H8fs,LoF,Suppressor
539,LS411N,ACH-000985,CVCL_1385,Bowel,SETD1B,Het,Frameshift,p.K42fs,LoF,Suppressor
540,LS411N,ACH-000985,CVCL_1385,Bowel,SETD1B,Het,Missense,p.V65A,,Suppressor
541,LS411N,ACH-000985,CVCL_1385,Bowel,SETD1B,Het,Missense,p.V723A,LoF,Suppressor
542,LS411N,ACH-000985,CVCL_1385,Bowel,TP53,Hom,Stopgain,p.Y126*,LoF,Suppressor
543,LS411N,ACH-000985,CVCL_1385,Bowel,WNK2,Het,Splice_site,p.S612S,LoF,Suppressor
544,LS411N,ACH-000985,CVCL_1385,Bowel,WNK2,Het,Splice_site,,LoF,Suppressor
545,LS411N,ACH-000985,CVCL_1385,Bowel,ZFHX3,Het,Missense,p.C3029Y,LoF,Suppressor
546,LS411N,ACH-000985,CVCL_1385,Bowel,ZFHX3,Het,Missense,p.P802L,,Suppressor
547,HOP62,ACH-000861,CVCL_1285,Lung,B2M,Het,Missense,p.E70Q,,Suppressor
548,HOP62,ACH-000861,CVCL_1285,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
549,HOP62,ACH-000861,CVCL_1285,Lung,MSH6,Het,Missense,p.E221D,,Suppressor
550,HOP62,ACH-000861,CVCL_1285,Lung,POLE,Het,Missense,p.K604N,,Suppressor
551,HOP62,ACH-000861,CVCL_1285,Lung,RAF1,Het,Missense,p.R143Q,,Oncogene
552,HOP62,ACH-000861,CVCL_1285,Lung,TERT,Het,Promoter,1-124C>T,GoF,Oncogene
553,HOP62,ACH-000861,CVCL_1285,Lung,TP53,Hom,Splice_site,,LoF,Suppressor
554,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,APC,Het,Missense,p.S770P,,Suppressor
555,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,ERBB2,Het,Missense,p.R678Q,GoF,Oncogene
556,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,FGFR3,Het,Missense,p.K651E,GoF,Oncogene
557,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,PIK3CA,Het,Missense,p.P124L,,Oncogene
558,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,PTEN,Hom,Frameshift,p.N212fs,LoF,Suppressor
559,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,RB1,Hom,Splice_site,,LoF,Suppressor
560,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,TERT,,Promoter,1-124C>T,GoF,Oncogene
561,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,TP53,Het,Missense,p.E271K,LoF,Suppressor
562,J82,ACH-000396,CVCL_0359,Bladder/Urinary Tract,TP53,Het,Missense,p.K320N,LoF,Suppressor
563,CCF-STTG1,ACH-000329,CVCL_1118,CNS/Brain,ARID1A,Het,Missense,p.P1144T,,Suppressor
564,CCF-STTG1,ACH-000329,CVCL_1118,CNS/Brain,PTEN,Hom,Missense,p.L112R,LoF,Suppressor
565,CCF-STTG1,ACH-000329,CVCL_1118,CNS/Brain,PTPN11,Het,Missense,p.R498W,GoF,Oncogene
566,BT-20,ACH-000536,CVCL_0178,Breast,BRCA2,Hom,Missense,p.T3357R,,Suppressor
567,BT-20,ACH-000536,CVCL_0178,Breast,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
568,BT-20,ACH-000536,CVCL_0178,Breast,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
569,BT-20,ACH-000536,CVCL_0178,Breast,EGFR,,Gain,GAIN,GoF,Oncogene
570,BT-20,ACH-000536,CVCL_0178,Breast,NRAS,,Gain,GAIN,GoF,Oncogene
571,BT-20,ACH-000536,CVCL_0178,Breast,PIK3CA,Het,Missense,p.H1047R,GoF,Oncogene
572,BT-20,ACH-000536,CVCL_0178,Breast,PIK3CA,Het,Missense,p.P539R,GoF,Oncogene
573,BT-20,ACH-000536,CVCL_0178,Breast,RB1,Hom,Missense,p.I388S,LoF,Suppressor
574,BT-20,ACH-000536,CVCL_0178,Breast,RB1,Het,Missense,p.P515L,LoF,Suppressor
575,BT-20,ACH-000536,CVCL_0178,Breast,TP53,Hom,Missense,p.K132Q,LoF,Suppressor
576,DU4475,ACH-000258,CVCL_1183,Breast,APC,Hom,Stopgain,p.E1577*,LoF,Suppressor
577,DU4475,ACH-000258,CVCL_1183,Breast,BRAF,Het,Missense,p.V600E,GoF,Oncogene
578,DU4475,ACH-000258,CVCL_1183,Breast,RB1,Hom,Deletion,DEL,LoF,Suppressor
579,DU4475,ACH-000258,CVCL_1183,Breast,SETD1B,Het,Missense,p.Q1402R,,Suppressor
580,DU4475,ACH-000258,CVCL_1183,Breast,ZFHX3,Het,Missense,p.A2398D,,Suppressor
581,LS 180,ACH-000957,CVCL_0397,Bowel,ACVR2A,Hom,Frameshift,p.K437fs,LoF,Suppressor
582,LS 180,ACH-000957,CVCL_0397,Bowel,APC,Het,Missense,p.R1788C,,Suppressor
583,LS 180,ACH-000957,CVCL_0397,Bowel,ARID1A,Het,Frameshift,p.K1094fs,LoF,Suppressor
584,LS 180,ACH-000957,CVCL_0397,Bowel,BRAF,Het,Missense,p.D211G,,Oncogene
585,LS 180,ACH-000957,CVCL_0397,Bowel,BRCA2,Het,Frameshift,p.T3033fs,LoF,Suppressor
586,LS 180,ACH-000957,CVCL_0397,Bowel,CTNNB1,Hom,Missense,p.S45F,GoF,Oncogene
587,LS 180,ACH-000957,CVCL_0397,Bowel,EP300,Het,Missense,p.G30V,,Suppressor
588,LS 180,ACH-000957,CVCL_0397,Bowel,HNF1A,Het,Frameshift,p.P291fs,LoF,Suppressor
589,LS 180,ACH-000957,CVCL_0397,Bowel,JAK1,Het,Missense,p.R681W,,Oncogene
590,LS 180,ACH-000957,CVCL_0397,Bowel,KRAS,Het,Missense,p.G12D,GoF,Oncogene
591,LS 180,ACH-000957,CVCL_0397,Bowel,PIK3CA,Het,Missense,p.H1047R,GoF,Oncogene
592,LS 180,ACH-000957,CVCL_0397,Bowel,PRDM2,Het,Frameshift,p.V1490fs,LoF,Suppressor
593,LS 180,ACH-000957,CVCL_0397,Bowel,PTEN,Het,Missense,p.I67K,LoF,Suppressor
594,LS 180,ACH-000957,CVCL_0397,Bowel,RNF43,Het,Missense,p.K108E,,Suppressor
595,LS 180,ACH-000957,CVCL_0397,Bowel,RNF43,Het,Missense,p.R389H,,Suppressor
596,LS 180,ACH-000957,CVCL_0397,Bowel,SETD1B,Hom,Frameshift,p.H8fs,LoF,Suppressor
597,LS 180,ACH-000957,CVCL_0397,Bowel,SETD1B,Het,Frameshift,p.Q1589fs,LoF,Suppressor
598,LS 180,ACH-000957,CVCL_0397,Bowel,STK11,Het,Missense,p.I46T,LoF,Suppressor
599,LS 180,ACH-000957,CVCL_0397,Bowel,TGFBR2,Hom,Frameshift,p.K128fs,LoF,Suppressor
600,LS 180,ACH-000957,CVCL_0397,Bowel,WNK2,Het,Missense,p.A1529T,,Suppressor
601,LS 180,ACH-000957,CVCL_0397,Bowel,WNK2,Het,Frameshift,p.D1638fs,LoF,Suppressor
602,LS 180,ACH-000957,CVCL_0397,Bowel,ZFHX3,Het,Frameshift,p.A3407fs,LoF,Suppressor
603,LS 180,ACH-000957,CVCL_0397,Bowel,ZFHX3,Het,Missense,p.D3699G,LoF,Suppressor
604,COLO 201,ACH-000253,CVCL_1987,Bowel,APC,Hom,Frameshift,p.T1556fs,LoF,Suppressor
605,COLO 201,ACH-000253,CVCL_1987,Bowel,BRAF,Het,Missense,p.V600E,GoF,Oncogene
606,COLO 201,ACH-000253,CVCL_1987,Bowel,CTNNB1,Hom,Missense,p.N287S,,Oncogene
607,COLO 201,ACH-000253,CVCL_1987,Bowel,GNAS,Het,Missense,p.S95I,,Oncogene
608,COLO 201,ACH-000253,CVCL_1987,Bowel,MTOR,Het,Missense,p.P1193L,,Oncogene
609,COLO 201,ACH-000253,CVCL_1987,Bowel,TP53,Hom,Frameshift,p.Y103fs,LoF,Suppressor
610,COLO 201,ACH-000253,CVCL_1987,Bowel,TP53,Hom,Frameshift,p.Y107fs,LoF,Suppressor
611,HepG2/C3A,ACH-001021,CVCL_1098,Liver,ATM,Het,Missense,p.V2906I,,Suppressor
612,HepG2/C3A,ACH-001021,CVCL_1098,Liver,EGFR,Het,Missense,p.C186S,,Oncogene
613,HepG2/C3A,ACH-001021,CVCL_1098,Liver,ERBB3,Het,Missense,p.R421K,,Oncogene
614,HepG2/C3A,ACH-001021,CVCL_1098,Liver,NRAS,Het,Missense,p.Q61L,GoF,Oncogene
615,HepG2/C3A,ACH-001021,CVCL_1098,Liver,TERT,,Promoter,1-124C>T,GoF,Oncogene
616,RPMI-7951,ACH-000348,CVCL_1666,Skin,BRAF,Het,Missense,p.V600E,GoF,Oncogene
617,RPMI-7951,ACH-000348,CVCL_1666,Skin,CDKN2A,Hom,Missense,p.L16R,LoF,Suppressor
618,RPMI-7951,ACH-000348,CVCL_1666,Skin,PTEN,Hom,Deletion,DEL,LoF,Suppressor
619,RPMI-7951,ACH-000348,CVCL_1666,Skin,TERT,,Promoter,242_243CC>TT,,Oncogene
620,RPMI-7951,ACH-000348,CVCL_1666,Skin,TP53,Hom,Stopgain,p.S166*,LoF,Suppressor
621,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,ACVR2A,Het,Frameshift,p.K437fs,LoF,Suppressor
622,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,ARID1A,Het,Frameshift,p.Y551fs,LoF,Suppressor
623,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,CDKN2B,Het,Missense,p.A23V,,Suppressor
624,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,FBXW7,Het,Missense,p.G104V,,Suppressor
625,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,KMT2D,Het,Missense,p.G4397V,,Suppressor
626,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,KMT2D,Het,Missense,p.P4209Q,,Suppressor
627,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,KRAS,Het,Missense,p.G13C,GoF,Oncogene
628,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,MSH6,Het,Missense,p.A35T,,Suppressor
629,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,NF1,Het,Frameshift,p.P678fs,LoF,Suppressor
630,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,PIK3CA,Het,Missense,p.H1047Y,GoF,Oncogene
631,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,POLE,Het,Missense,p.D2166N,,Suppressor
632,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,POLE,Het,Missense,p.S828Y,LoF,Suppressor
633,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,PRDM2,Het,Missense,p.E278D,,Suppressor
634,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,PTEN,Het,Frameshift,p.K267fs,LoF,Suppressor
635,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,RNF43,Het,Missense,p.C298Y,LoF,Suppressor
636,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,RNF43,Het,Frameshift,p.G659fs,LoF,Suppressor
637,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,SETD1B,Het,Missense,p.E1078D,,Suppressor
638,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,SMARCA4,Het,Stopgain,p.E419*,LoF,Suppressor
639,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,STK11,Hom,Frameshift,p.P281fs,LoF,Suppressor
640,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,WNK2,Het,Stopgain,p.G1139*,LoF,Suppressor
641,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,WNK2,Het,Missense,p.L71P,,Suppressor
642,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,WNK2,Het,Missense,p.S1520N,,Suppressor
643,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,ZFHX3,Het,Frameshift,p.A3407fs,LoF,Suppressor
644,TOV-21G,ACH-000885,CVCL_3613,Ovary/Fallopian Tube,ZFHX3,Het,Missense,p.P2787L,,Suppressor
645,Panc 10.05,ACH-000060,CVCL_1639,Pancreas,EP300,Hom,Frameshift,p.K1488fs,LoF,Suppressor
646,Panc 10.05,ACH-000060,CVCL_1639,Pancreas,KRAS,Het,Missense,p.G12D,GoF,Oncogene
647,Panc 10.05,ACH-000060,CVCL_1639,Pancreas,NF1,Het,Missense,p.G1417S,LoF,Suppressor
648,Panc 10.05,ACH-000060,CVCL_1639,Pancreas,RNF43,Hom,Frameshift,p.M18fs,LoF,Suppressor
649,Panc 10.05,ACH-000060,CVCL_1639,Pancreas,TGFBR2,Hom,Frameshift,p.S156fs,LoF,Suppressor
650,Panc 10.05,ACH-000060,CVCL_1639,Pancreas,TP53,Hom,Missense,p.I255N,LoF,Suppressor
651,HCT116,ACH-000971,CVCL_0291,Bowel,ABL1,Het,Missense,p.Y276C,,Oncogene
652,HCT116,ACH-000971,CVCL_0291,Bowel,ACVR2A,Hom,Frameshift,p.K437fs,LoF,Suppressor
653,HCT116,ACH-000971,CVCL_0291,Bowel,ATM,Het,Missense,p.A1127V,,Suppressor
654,HCT116,ACH-000971,CVCL_0291,Bowel,BRCA2,Het,Frameshift,p.I2675fs,LoF,Suppressor
655,HCT116,ACH-000971,CVCL_0291,Bowel,CDKN2A,Het,Frameshift,p.E33fs,LoF,Suppressor
656,HCT116,ACH-000971,CVCL_0291,Bowel,CDKN2A,Het,Frameshift,p.R24fs,LoF,Suppressor
657,HCT116,ACH-000971,CVCL_0291,Bowel,CHEK2,Het,Missense,p.L355P,LoF,Suppressor
658,HCT116,ACH-000971,CVCL_0291,Bowel,CTNNB1,Het,Missense,p.S45NA,,Oncogene
659,HCT116,ACH-000971,CVCL_0291,Bowel,EP300,Het,Frameshift,p.M1470fs,LoF,Suppressor
660,HCT116,ACH-000971,CVCL_0291,Bowel,EP300,Het,Frameshift,p.N1700fs,LoF,Suppressor
661,HCT116,ACH-000971,CVCL_0291,Bowel,GNAS,Het,Missense,p.Y318C,,Oncogene
662,HCT116,ACH-000971,CVCL_0291,Bowel,HNF1A,Het,Frameshift,p.P291fs,LoF,Suppressor
663,HCT116,ACH-000971,CVCL_0291,Bowel,KMT2D,Het,Frameshift,p.R2443fs,LoF,Suppressor
664,HCT116,ACH-000971,CVCL_0291,Bowel,KMT2D,Het,Missense,p.V160M,LoF,Suppressor
665,HCT116,ACH-000971,CVCL_0291,Bowel,KRAS,Het,Missense,p.G13D,GoF,Oncogene
666,HCT116,ACH-000971,CVCL_0291,Bowel,NF1,Het,Missense,p.P388T,LoF,Suppressor
667,HCT116,ACH-000971,CVCL_0291,Bowel,PIK3CA,Het,Missense,p.H1047R,GoF,Oncogene
668,HCT116,ACH-000971,CVCL_0291,Bowel,PRDM2,Hom,Frameshift,p.V1490fs,LoF,Suppressor
669,HCT116,ACH-000971,CVCL_0291,Bowel,SETD1B,Hom,Frameshift,p.H8fs,LoF,Suppressor
670,HCT116,ACH-000971,CVCL_0291,Bowel,SETD1B,Het,Frameshift,p.R1623fs,LoF,Suppressor
671,HCT116,ACH-000971,CVCL_0291,Bowel,SETD1B,Het,Frameshift,p.S1055fs,LoF,Suppressor
672,HCT116,ACH-000971,CVCL_0291,Bowel,SMARCA4,Het,Missense,p.L1163P,LoF,Suppressor
673,HCT116,ACH-000971,CVCL_0291,Bowel,SMARCA4,Het,Frameshift,p.S122fs,LoF,Suppressor
674,HCT116,ACH-000971,CVCL_0291,Bowel,TGFBR2,Hom,Frameshift,p.K128fs,LoF,Suppressor
675,HCT116,ACH-000971,CVCL_0291,Bowel,WNK2,Het,Frameshift,p.D1638fs,LoF,Suppressor
676,HCT116,ACH-000971,CVCL_0291,Bowel,WNK2,Het,Frameshift,p.H758fs,LoF,Suppressor
677,HCT116,ACH-000971,CVCL_0291,Bowel,ZFHX3,Het,Missense,p.G3519S,,Suppressor
678,Panc 03.27,ACH-000139,CVCL_1635,Pancreas,ATM,Het,Missense,p.E2351G,LoF,Suppressor
679,Panc 03.27,ACH-000139,CVCL_1635,Pancreas,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
680,Panc 03.27,ACH-000139,CVCL_1635,Pancreas,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
681,Panc 03.27,ACH-000139,CVCL_1635,Pancreas,KRAS,Het,Missense,p.G12V,GoF,Oncogene
682,Panc 03.27,ACH-000139,CVCL_1635,Pancreas,TP53,Hom,Splice_site,375+5G>T,LoF,Suppressor
683,Panc 03.27,ACH-000139,CVCL_1635,Pancreas,ZFHX3,Hom,Missense,p.P802A,,Suppressor
684,Hs 852.T,ACH-000274,CVCL_0950,Skin,CCND1,,Gain,GAIN,GoF,Oncogene
685,Hs 852.T,ACH-000274,CVCL_0950,Skin,EGFR,,Gain,GAIN,GoF,Oncogene
686,Hs 852.T,ACH-000274,CVCL_0950,Skin,FGFR3,,Gain,GAIN,GoF,Oncogene
687,Hs 852.T,ACH-000274,CVCL_0950,Skin,NRAS,Het,Missense,p.G12V,GoF,Oncogene
688,Hs 852.T,ACH-000274,CVCL_0950,Skin,POLE,Het,Missense,p.R2159H,,Suppressor
689,Hs 852.T,ACH-000274,CVCL_0950,Skin,TERT,,Gain,GAIN,GoF,Oncogene
690,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,CDKN2A,Het,Missense,p.D23P,,Suppressor
691,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,CDKN2B,Het,Missense,p.D76A,LoF,Suppressor
692,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,CTNNB1,Het,Missense,p.G34E,GoF,Oncogene
693,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,EP300,Het,Stopgain,p.E1025*,LoF,Suppressor
694,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,EP300,Het,Stopgain,p.E643*,LoF,Suppressor
695,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,EP300,Het,Missense,p.K350R,LoF,Suppressor
696,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,GNAS,Het,Missense,p.F219V,,Oncogene
697,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,KRAS,Het,Missense,p.G12D,GoF,Oncogene
698,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,NF1,Het,Missense,p.E1438G,LoF,Suppressor
699,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,PIK3CA,Het,Missense,p.E453K,GoF,Oncogene
700,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,PIK3CA,Het,Missense,p.E545A,GoF,Oncogene
701,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,PRDM2,Het,Missense,p.P1326S,,Suppressor
702,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,SOS1,Het,Missense,p.E783G,,Oncogene
703,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,XPO1,Het,Missense,p.C585F,,Oncogene
704,AGS,ACH-000880,CVCL_0139,Esophagus/Stomach,ZFHX3,Het,Missense,p.F3474L,LoF,Suppressor
705,NCI-N87,ACH-000427,CVCL_1603,Esophagus/Stomach,ERBB2,,Gain,GAIN,GoF,Oncogene
706,NCI-N87,ACH-000427,CVCL_1603,Esophagus/Stomach,ERBB3,,Missense,p.T757K,,Oncogene
707,NCI-N87,ACH-000427,CVCL_1603,Esophagus/Stomach,KMT2D,Het,Missense,p.S537F,,Suppressor
708,NCI-N87,ACH-000427,CVCL_1603,Esophagus/Stomach,LASP1,,Gain,GAIN,GoF,Oncogene
709,NCI-N87,ACH-000427,CVCL_1603,Esophagus/Stomach,SETD1B,Het,Missense,p.Q1589P,,Suppressor
710,NCI-N87,ACH-000427,CVCL_1603,Esophagus/Stomach,SMAD4,Hom,Deletion,DEL,LoF,Suppressor
711,NCI-N87,ACH-000427,CVCL_1603,Esophagus/Stomach,TP53,Hom,Missense,p.R248Q,LoF,Suppressor
712,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,ARID1A,Hom,Deletion,DEL,LoF,Suppressor
713,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,BRCA2,Het,Missense,p.E2292A,LoF,Suppressor
714,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,CDKN2A,Hom,Stopgain,p.R29*,LoF,Suppressor
715,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,MET,,Gain,GAIN,GoF,Oncogene
716,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,STK11,Het,Missense,p.P149L,LoF,Suppressor
717,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,TP53,,Missense,p.G262_269NA,,Suppressor
718,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,TP53,Het,Splice_site,,LoF,Suppressor
719,SNU-5,ACH-000303,CVCL_0078,Esophagus/Stomach,ZFHX3,Hom,Missense,p.S1608G,,Suppressor
720,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ACVR2A,Het,Missense,p.A349T,,Suppressor
721,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ACVR2A,Het,Missense,p.L329M,LoF,Suppressor
722,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ARID1A,Het,Missense,p.G1544C,,Suppressor
723,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ARID1A,Het,Stopgain,p.Q1618*,LoF,Suppressor
724,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ARID1A,Het,Stopgain,p.Q1898*,LoF,Suppressor
725,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ARID1A,Het,Missense,p.Q404H,,Suppressor
726,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ATM,Het,Missense,p.P2353H,LoF,Suppressor
727,HEC-1-A,ACH-000954,CVCL_0293,Uterus,BRAF,Het,Missense,p.R682Q,,Oncogene
728,HEC-1-A,ACH-000954,CVCL_0293,Uterus,EP300,Het,Missense,p.D1399N,LoF,Suppressor
729,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ERBB2,Het,Missense,p.T798I,GoF,Oncogene
730,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ERBB2,Het,Missense,p.V842I,GoF,Oncogene
731,HEC-1-A,ACH-000954,CVCL_0293,Uterus,KMT2D,Het,Missense,p.P2641H,,Suppressor
732,HEC-1-A,ACH-000954,CVCL_0293,Uterus,KRAS,Het,Missense,p.G12D,GoF,Oncogene
733,HEC-1-A,ACH-000954,CVCL_0293,Uterus,MET,Het,Missense,p.V1350D,,Oncogene
734,HEC-1-A,ACH-000954,CVCL_0293,Uterus,MSH6,Het,Frameshift,p.F1088fs,LoF,Suppressor
735,HEC-1-A,ACH-000954,CVCL_0293,Uterus,MSH6,Het,Splice_site,,LoF,Suppressor
736,HEC-1-A,ACH-000954,CVCL_0293,Uterus,MTOR,Het,Missense,p.R2254M,,Oncogene
737,HEC-1-A,ACH-000954,CVCL_0293,Uterus,NF1,Het,Missense,p.L792I,,Suppressor
738,HEC-1-A,ACH-000954,CVCL_0293,Uterus,PIK3CA,Het,Missense,p.G1049R,GoF,Oncogene
739,HEC-1-A,ACH-000954,CVCL_0293,Uterus,PMS2,Hom,Stopgain,p.R802*,LoF,Suppressor
740,HEC-1-A,ACH-000954,CVCL_0293,Uterus,PRDM2,Het,Missense,p.N1324I,,Suppressor
741,HEC-1-A,ACH-000954,CVCL_0293,Uterus,RNF43,Het,Frameshift,p.G659fs,LoF,Suppressor
742,HEC-1-A,ACH-000954,CVCL_0293,Uterus,SETD1B,Het,Frameshift,p.H8fs,LoF,Suppressor
743,HEC-1-A,ACH-000954,CVCL_0293,Uterus,SETD1B,Het,Frameshift,p.P1361fs,LoF,Suppressor
744,HEC-1-A,ACH-000954,CVCL_0293,Uterus,SMAD4,Het,Missense,p.L344S,LoF,Suppressor
745,HEC-1-A,ACH-000954,CVCL_0293,Uterus,SMARCA4,Het,Frameshift,p.G271fs,LoF,Suppressor
746,HEC-1-A,ACH-000954,CVCL_0293,Uterus,TP53,Hom,Missense,p.R248Q,LoF,Suppressor
747,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ZFHX3,Het,Stopgain,p.R1114*,LoF,Suppressor
748,HEC-1-A,ACH-000954,CVCL_0293,Uterus,ZFHX3,Het,Frameshift,p.S2505fs,LoF,Suppressor
749,C-33 A,ACH-001333,CVCL_1094,Cervix,ARID1A,Het,Frameshift,p.Q758fs,LoF,Suppressor
750,C-33 A,ACH-001333,CVCL_1094,Cervix,BRCA2,Het,Missense,p.A3029T,,Suppressor
751,C-33 A,ACH-001333,CVCL_1094,Cervix,HNF1A,Het,Frameshift,p.P291fs,LoF,Suppressor
752,C-33 A,ACH-001333,CVCL_1094,Cervix,KMT2D,Het,Frameshift,p.A2119fs,LoF,Suppressor
753,C-33 A,ACH-001333,CVCL_1094,Cervix,KMT2D,Het,Missense,p.R1614W,LoF,Suppressor
754,C-33 A,ACH-001333,CVCL_1094,Cervix,KMT2D,Het,Missense,p.R1617W,LoF,Suppressor
755,C-33 A,ACH-001333,CVCL_1094,Cervix,KMT2D,Het,Frameshift,p.V1244fs,LoF,Suppressor
756,C-33 A,ACH-001333,CVCL_1094,Cervix,PIK3CA,Het,Missense,p.R88Q,GoF,Oncogene
757,C-33 A,ACH-001333,CVCL_1094,Cervix,PTEN,Het,Stopgain,p.R130*,LoF,Suppressor
758,C-33 A,ACH-001333,CVCL_1094,Cervix,PTEN,Het,Stopgain,p.R233*,LoF,Suppressor
759,C-33 A,ACH-001333,CVCL_1094,Cervix,RB1,Hom,Splice_site,,LoF,Suppressor
760,C-33 A,ACH-001333,CVCL_1094,Cervix,SETD1B,Het,Frameshift,p.H8fs,LoF,Suppressor
761,C-33 A,ACH-001333,CVCL_1094,Cervix,SETD1B,Het,Missense,p.R980W,,Suppressor
762,C-33 A,ACH-001333,CVCL_1094,Cervix,SETD1B,Het,Missense,p.T482M,,Suppressor
763,C-33 A,ACH-001333,CVCL_1094,Cervix,SMARCA4,Het,Missense,p.M527T,LoF,Suppressor
764,C-33 A,ACH-001333,CVCL_1094,Cervix,SMARCA4,Het,Missense,p.Q1248R,LoF,Suppressor
765,C-33 A,ACH-001333,CVCL_1094,Cervix,SMARCA4,Het,Stopgain,p.Q1537*,LoF,Suppressor
766,C-33 A,ACH-001333,CVCL_1094,Cervix,TP53,Hom,Missense,p.R273C,LoF,Suppressor
767,C-33 A,ACH-001333,CVCL_1094,Cervix,WNK2,Het,Missense,p.A678T,,Suppressor
768,C-33 A,ACH-001333,CVCL_1094,Cervix,WNK2,Het,Frameshift,p.D1638fs,LoF,Suppressor
769,C-33 A,ACH-001333,CVCL_1094,Cervix,ZFHX3,Het,Frameshift,p.R1893fs,LoF,Suppressor
770,SK-HEP-1,ACH-000361,CVCL_0525,Liver,BRAF,Het,Missense,p.V600E,GoF,Oncogene
771,SK-HEP-1,ACH-000361,CVCL_0525,Liver,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
772,SK-HEP-1,ACH-000361,CVCL_0525,Liver,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
773,SK-HEP-1,ACH-000361,CVCL_0525,Liver,NF2,Het,Missense,p.I264V,,Suppressor
774,SK-HEP-1,ACH-000361,CVCL_0525,Liver,SMARCA4,Hom,Stopgain,p.E1582*,LoF,Suppressor
775,NCI-H1573,ACH-000916,CVCL_1478,Lung,CDKN2A,Het,Missense,p.D23P,,Suppressor
776,NCI-H1573,ACH-000916,CVCL_1478,Lung,EGFR,,Gain,GAIN,GoF,Oncogene
777,NCI-H1573,ACH-000916,CVCL_1478,Lung,ERBB3,Het,Missense,p.E332K,GoF,Oncogene
778,NCI-H1573,ACH-000916,CVCL_1478,Lung,FBXW7,Het,Missense,p.V619L,,Suppressor
779,NCI-H1573,ACH-000916,CVCL_1478,Lung,FBXW7,Het,Stopgain,p.W593*,LoF,Suppressor
780,NCI-H1573,ACH-000916,CVCL_1478,Lung,KMT2D,Het,Missense,p.L2398P,,Suppressor
781,NCI-H1573,ACH-000916,CVCL_1478,Lung,KMT2D,Het,Missense,p.V361F,,Suppressor
782,NCI-H1573,ACH-000916,CVCL_1478,Lung,KRAS,Het,Missense,p.G12A,GoF,Oncogene
783,NCI-H1573,ACH-000916,CVCL_1478,Lung,MET,,Gain,GAIN,GoF,Oncogene
784,NCI-H1573,ACH-000916,CVCL_1478,Lung,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
785,NCI-H1573,ACH-000916,CVCL_1478,Lung,PIK3R1,Het,Stopgain,p.G71*,LoF,Suppressor
786,NCI-H1573,ACH-000916,CVCL_1478,Lung,PTPN11,Het,Stopgain,p.R351*,,Oncogene
787,NCI-H1573,ACH-000916,CVCL_1478,Lung,RNF43,Het,Missense,p.A605G,,Suppressor
788,NCI-H1573,ACH-000916,CVCL_1478,Lung,SMARCA4,Hom,Stopgain,p.E1399*,LoF,Suppressor
789,NCI-H1573,ACH-000916,CVCL_1478,Lung,STK11,Het,Missense,p.S216F,LoF,Suppressor
790,NCI-H1573,ACH-000916,CVCL_1478,Lung,TP53,Hom,Missense,p.R248L,LoF,Suppressor
791,SK-MEL-2,ACH-001190,CVCL_0069,Skin,CCND1,,Gain,GAIN,GoF,Oncogene
792,SK-MEL-2,ACH-001190,CVCL_0069,Skin,EP300,Het,Missense,p.P989S,,Suppressor
793,SK-MEL-2,ACH-001190,CVCL_0069,Skin,NRAS,Het,Missense,p.Q61R,GoF,Oncogene
794,SK-MEL-2,ACH-001190,CVCL_0069,Skin,POLE,Het,Missense,p.T1052A,,Suppressor
795,SK-MEL-2,ACH-001190,CVCL_0069,Skin,SETD1B,Het,Frameshift,p.L1255fs,LoF,Suppressor
796,SK-MEL-2,ACH-001190,CVCL_0069,Skin,TERT,,Promoter,1-146C>T,GoF,Oncogene
797,SK-MEL-2,ACH-001190,CVCL_0069,Skin,TP53,Hom,Missense,p.G245S,LoF,Suppressor
798,SK-MEL-2,ACH-001190,CVCL_0069,Skin,ZFHX3,Het,Frameshift,p.H3611fs,LoF,Suppressor
799,NCI-H1155,ACH-000980,CVCL_1456,Lung,APC,Het,Stopgain,p.R232*,LoF,Suppressor
800,NCI-H1155,ACH-000980,CVCL_1456,Lung,EGFR,Het,Missense,p.R264G,,Oncogene
801,NCI-H1155,ACH-000980,CVCL_1456,Lung,EP300,Hom,Splice_site,,LoF,Suppressor
802,NCI-H1155,ACH-000980,CVCL_1456,Lung,KMT2D,Het,Missense,p.A3561D,,Suppressor
803,NCI-H1155,ACH-000980,CVCL_1456,Lung,KMT2D,Het,Missense,p.V38M,,Suppressor
804,NCI-H1155,ACH-000980,CVCL_1456,Lung,KRAS,Hom,Missense,p.Q61H,GoF,Oncogene
805,NCI-H1155,ACH-000980,CVCL_1456,Lung,LASP1,Het,Missense,p.A209V,,Oncogene
806,NCI-H1155,ACH-000980,CVCL_1456,Lung,MSH6,Hom,Stopgain,p.R911*,LoF,Suppressor
807,NCI-H1155,ACH-000980,CVCL_1456,Lung,NF2,Het,Missense,p.A403T,,Suppressor
808,NCI-H1155,ACH-000980,CVCL_1456,Lung,PIK3CA,Het,Missense,p.D843E,,Oncogene
809,NCI-H1155,ACH-000980,CVCL_1456,Lung,PTEN,Hom,Stopgain,p.R233*,LoF,Suppressor
810,NCI-H1155,ACH-000980,CVCL_1456,Lung,RB1,Het,Stopgain,p.R467*,LoF,Suppressor
811,NCI-H1155,ACH-000980,CVCL_1456,Lung,SMAD4,Het,Frameshift,p.R38fs,LoF,Suppressor
812,NCI-H1155,ACH-000980,CVCL_1456,Lung,SMARCA4,Het,Missense,p.R466L,,Suppressor
813,NCI-H1155,ACH-000980,CVCL_1456,Lung,SMARCA4,Het,Missense,p.S1238P,LoF,Suppressor
814,NCI-H1155,ACH-000980,CVCL_1456,Lung,TP53,Hom,Missense,p.R273H,LoF,Suppressor
815,NCI-H1155,ACH-000980,CVCL_1456,Lung,ZFHX3,Het,Missense,p.A896T,,Suppressor
816,NCI-H460,ACH-000463,CVCL_0459,Lung,ARID1A,Hom,Missense,p.LI1917del,,Suppressor
817,NCI-H460,ACH-000463,CVCL_0459,Lung,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
818,NCI-H460,ACH-000463,CVCL_0459,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
819,NCI-H460,ACH-000463,CVCL_0459,Lung,KRAS,Hom,Missense,p.Q61H,GoF,Oncogene
820,NCI-H460,ACH-000463,CVCL_0459,Lung,MAP2K1,Het,Missense,p.Y134C,,Oncogene
821,NCI-H460,ACH-000463,CVCL_0459,Lung,MYC,,Gain,GAIN,GoF,Oncogene
822,NCI-H460,ACH-000463,CVCL_0459,Lung,PIK3CA,Het,Missense,p.E545K,GoF,Oncogene
823,NCI-H460,ACH-000463,CVCL_0459,Lung,STK11,Hom,Stopgain,p.Q37*,LoF,Suppressor
824,NCI-H460,ACH-000463,CVCL_0459,Lung,ZFHX3,Het,Missense,p.P3675Q,,Suppressor
825,NCI-H1299,ACH-000510,CVCL_0060,Lung,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
826,NCI-H1299,ACH-000510,CVCL_0060,Lung,SMARCA4,Hom,Splice_site,,LoF,Suppressor
827,NCI-H1299,ACH-000510,CVCL_0060,Lung,SOS1,Het,Missense,p.Y215H,,Oncogene
828,NCI-H1299,ACH-000510,CVCL_0060,Lung,TP53,Hom,Deletion,DEL,LoF,Suppressor
829,NCI-H1299,ACH-000510,CVCL_0060,Lung,ZFHX3,Het,Missense,p.F3044V,LoF,Suppressor
830,NCI-H661,ACH-000853,CVCL_1577,Lung,BRCA2,Het,Missense,p.G2584V,LoF,Suppressor
831,NCI-H661,ACH-000853,CVCL_1577,Lung,CDKN2A,Hom,Splice_site,,LoF,Suppressor
832,NCI-H661,ACH-000853,CVCL_1577,Lung,LASP1,Het,Stopgain,p.E48*,,Oncogene
833,NCI-H661,ACH-000853,CVCL_1577,Lung,PTPN11,Het,Missense,p.N58S,,Oncogene
834,NCI-H661,ACH-000853,CVCL_1577,Lung,SMARCA4,Hom,Frameshift,p.L1161fs,LoF,Suppressor
835,NCI-H661,ACH-000853,CVCL_1577,Lung,TP53,Het,Missense,p.R158L,LoF,Suppressor
836,NCI-H661,ACH-000853,CVCL_1577,Lung,TP53,Het,Missense,p.S215I,LoF,Suppressor
837,NCI-H661,ACH-000853,CVCL_1577,Lung,WNK2,Hom,Frameshift,p.G64fs,LoF,Suppressor
838,NCI-H661,ACH-000853,CVCL_1577,Lung,ZFHX3,Het,Missense,p.H2506P,,Suppressor
839,NCI-H596,ACH-000628,CVCL_1571,Lung,KMT2D,Het,Missense,p.M4058V,,Suppressor
840,NCI-H596,ACH-000628,CVCL_1571,Lung,PIK3CA,Het,Missense,p.E545K,GoF,Oncogene
841,NCI-H596,ACH-000628,CVCL_1571,Lung,RB1,Hom,Frameshift,p.S182fs,LoF,Suppressor
842,NCI-H596,ACH-000628,CVCL_1571,Lung,TGFBR2,Hom,Frameshift,p.S75fs,LoF,Suppressor
843,NCI-H596,ACH-000628,CVCL_1571,Lung,TP53,Hom,Missense,p.G245C,LoF,Suppressor
844,A-427,ACH-000757,CVCL_1055,Lung,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
845,A-427,ACH-000757,CVCL_1055,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
846,A-427,ACH-000757,CVCL_1055,Lung,CTNNB1,Hom,Missense,p.T41A,GoF,Oncogene
847,A-427,ACH-000757,CVCL_1055,Lung,KRAS,Het,Missense,p.G12D,GoF,Oncogene
848,A-427,ACH-000757,CVCL_1055,Lung,POLE,Hom,Missense,p.R37L,,Suppressor
849,A-427,ACH-000757,CVCL_1055,Lung,SMARCA4,Het,Missense,p.A1307D,LoF,Suppressor
850,Panc 08.13,ACH-000417,CVCL_1638,Pancreas,ATM,Het,Missense,p.F1234S,LoF,Suppressor
851,Panc 08.13,ACH-000417,CVCL_1638,Pancreas,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
852,Panc 08.13,ACH-000417,CVCL_1638,Pancreas,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
853,Panc 08.13,ACH-000417,CVCL_1638,Pancreas,KRAS,Hom,Missense,p.G12D,GoF,Oncogene
854,Panc 08.13,ACH-000417,CVCL_1638,Pancreas,SMAD4,Hom,Frameshift,p.C123fs,LoF,Suppressor
855,CHP-212,ACH-000120,CVCL_1125,Peripheral Nervous System,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
856,H4,ACH-000389,CVCL_1239,CNS/Brain,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
857,H4,ACH-000389,CVCL_1239,CNS/Brain,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
858,H4,ACH-000389,CVCL_1239,CNS/Brain,PTEN,Hom,Deletion,DEL,LoF,Suppressor
859,H4,ACH-000389,CVCL_1239,CNS/Brain,TERT,,Promoter,1-124C>T,GoF,Oncogene
860,A498,ACH-000555,CVCL_1056,Kidney,APC,Het,Missense,p.C1270R,LoF,Suppressor
861,A498,ACH-000555,CVCL_1056,Kidney,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
862,A498,ACH-000555,CVCL_1056,Kidney,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
863,A498,ACH-000555,CVCL_1056,Kidney,PIK3CB,Het,Missense,p.D1067V,GoF,Oncogene
864,A498,ACH-000555,CVCL_1056,Kidney,SMARCA4,Het,Missense,p.A923P,LoF,Suppressor
865,A498,ACH-000555,CVCL_1056,Kidney,VHL,Hom,Frameshift,p.G144fs,LoF,Suppressor
866,SW 1088,ACH-000437,CVCL_1715,CNS/Brain,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
867,SW 1088,ACH-000437,CVCL_1715,CNS/Brain,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
868,SW 1088,ACH-000437,CVCL_1715,CNS/Brain,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
869,SW 1088,ACH-000437,CVCL_1715,CNS/Brain,POLE,Het,Missense,p.V1270F,,Suppressor
870,SW 1088,ACH-000437,CVCL_1715,CNS/Brain,PTEN,Hom,Deletion,DEL,LoF,Suppressor
871,SW 1088,ACH-000437,CVCL_1715,CNS/Brain,TP53,Hom,Missense,p.R273C,LoF,Suppressor
872,BT-483,ACH-000818,CVCL_2319,Breast,APC,Het,Missense,p.T1160K,LoF,Suppressor
873,BT-483,ACH-000818,CVCL_2319,Breast,NF1,Het,Missense,p.R1204W,LoF,Suppressor
874,BT-483,ACH-000818,CVCL_2319,Breast,PIK3CA,Het,Missense,p.E542K,GoF,Oncogene
875,BT-483,ACH-000818,CVCL_2319,Breast,TP53,Het,Missense,p.M246I,LoF,Suppressor
876,BT-483,ACH-000818,CVCL_2319,Breast,WNK2,Het,Missense,p.L1162P,,Suppressor
877,SNU-423,ACH-000493,CVCL_0366,Liver,ARID1A,Hom,Stopgain,p.G623*,LoF,Suppressor
878,SNU-423,ACH-000493,CVCL_0366,Liver,RNF43,Het,Missense,p.I485V,,Suppressor
879,SNU-423,ACH-000493,CVCL_0366,Liver,TERT,,Promoter,1-124C>T,GoF,Oncogene
880,SNU-423,ACH-000493,CVCL_0366,Liver,TP53,Hom,Splice_site,,LoF,Suppressor
881,SW 1271,ACH-000890,CVCL_1716,Lung,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
882,SW 1271,ACH-000890,CVCL_1716,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
883,SW 1271,ACH-000890,CVCL_1716,Lung,NRAS,Hom,Missense,p.Q61R,GoF,Oncogene
884,SW 1271,ACH-000890,CVCL_1716,Lung,PMS2,Het,Missense,p.H88Y,,Suppressor
885,SW 1271,ACH-000890,CVCL_1716,Lung,SMARCA4,Hom,Missense,p.N774K,LoF,Suppressor
886,SW 1271,ACH-000890,CVCL_1716,Lung,TP53,Hom,Missense,p.C277F,LoF,Suppressor
887,Hs 695T,ACH-000799,CVCL_0851,Skin,ATM,Hom,Stopgain,p.Q1825*,LoF,Suppressor
888,Hs 695T,ACH-000799,CVCL_0851,Skin,BRAF,Het,Missense,p.V600E,GoF,Oncogene
889,Hs 695T,ACH-000799,CVCL_0851,Skin,BRCA2,Het,Missense,p.K2950N,,Suppressor
890,Hs 695T,ACH-000799,CVCL_0851,Skin,NF1,Het,Stopgain,p.Q959*,LoF,Suppressor
891,Hs 695T,ACH-000799,CVCL_0851,Skin,POLE,Het,Missense,p.V1270F,,Suppressor
892,Hs 695T,ACH-000799,CVCL_0851,Skin,TERT,,Promoter,1-146C>T,GoF,Oncogene
893,C32,ACH-000580,CVCL_1097,Skin,BRAF,Het,Missense,p.V600E,GoF,Oncogene
894,C32,ACH-000580,CVCL_1097,Skin,CDKN2A,Hom,Stoploss,Ter157Serext*13,,Suppressor
895,C32,ACH-000580,CVCL_1097,Skin,PTEN,Hom,Deletion,DEL,LoF,Suppressor
896,C32,ACH-000580,CVCL_1097,Skin,TERT,,Promoter,1-124C>T,GoF,Oncogene
897,KATO III,ACH-000793,CVCL_0371,Esophagus/Stomach,ATM,Het,Missense,p.S2581I,,Suppressor
898,KATO III,ACH-000793,CVCL_0371,Esophagus/Stomach,BRCA2,Het,Missense,p.G2044V,,Suppressor
899,KATO III,ACH-000793,CVCL_0371,Esophagus/Stomach,CTNNB1,,Gain,GAIN,GoF,Oncogene
900,KATO III,ACH-000793,CVCL_0371,Esophagus/Stomach,FGFR2,,Gain,GAIN,GoF,Oncogene
901,KATO III,ACH-000793,CVCL_0371,Esophagus/Stomach,KMT2D,Het,Missense,p.A3242P,,Suppressor
902,KATO III,ACH-000793,CVCL_0371,Esophagus/Stomach,KMT2D,Het,Stopgain,p.E1747*,LoF,Suppressor
903,KATO III,ACH-000793,CVCL_0371,Esophagus/Stomach,TP53,,Deletion,DEL,LoF,Suppressor
904,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,ARID1A,Het,Frameshift,p.D1633fs,LoF,Suppressor
905,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,ARID1A,Het,Missense,p.P121S,,Suppressor
906,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,ARID1A,Het,Frameshift,p.Q372fs,LoF,Suppressor
907,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,ATM,Het,Frameshift,p.L1154fs,LoF,Suppressor
908,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,BRCA2,Het,Missense,p.R1190W,,Suppressor
909,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,BRCA2,Het,Frameshift,p.S309fs,LoF,Suppressor
910,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,JAK1,Het,Frameshift,p.K860fs,,Oncogene
911,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,KMT2D,Het,Frameshift,p.A2119fs,LoF,Suppressor
912,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,KMT2D,Het,Missense,p.P2363del,,Suppressor
913,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,KMT2D,Het,Missense,p.R5030C,LoF,Suppressor
914,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,KRAS,Het,Missense,p.G12D,GoF,Oncogene
915,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,PRDM2,Het,Missense,p.S67F,LoF,Suppressor
916,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,SETD1B,Hom,Frameshift,p.H8fs,LoF,Suppressor
917,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,SMAD3,Het,Frameshift,p.V380fs,LoF,Suppressor
918,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,SMAD4,Het,Missense,p.R265H,LoF,Suppressor
919,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,TGFBR2,Het,Frameshift,p.S409fs,LoF,Suppressor
920,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,WNK2,Het,Missense,p.G1850C,,Suppressor
921,SNU-1,ACH-000932,CVCL_0099,Esophagus/Stomach,WNK2,Het,Missense,p.W547C,,Suppressor
922,AN3 CA,ACH-000940,CVCL_0028,Uterus,ARID1A,Het,Frameshift,p.D1633fs,LoF,Suppressor
923,AN3 CA,ACH-000940,CVCL_0028,Uterus,ARID1A,Het,Missense,p.LEMLRENT1836del,,Suppressor
924,AN3 CA,ACH-000940,CVCL_0028,Uterus,FBXW7,Het,Missense,p.R361W,LoF,Suppressor
925,AN3 CA,ACH-000940,CVCL_0028,Uterus,FGFR2,Het,Missense,p.K82R,GoF,Oncogene
926,AN3 CA,ACH-000940,CVCL_0028,Uterus,FGFR2,Hom,Missense,p.N321K,GoF,Oncogene
927,AN3 CA,ACH-000940,CVCL_0028,Uterus,HRAS,Het,Missense,p.F82L,,Oncogene
928,AN3 CA,ACH-000940,CVCL_0028,Uterus,KMT2D,Het,Frameshift,p.P2210fs,LoF,Suppressor
929,AN3 CA,ACH-000940,CVCL_0028,Uterus,MAPK3,Het,Missense,p.P373S,,Oncogene
930,AN3 CA,ACH-000940,CVCL_0028,Uterus,MET,Het,Missense,p.G344R,,Oncogene
931,AN3 CA,ACH-000940,CVCL_0028,Uterus,PIK3R1,Het,Missense,p.R557_561NA,,Suppressor
932,AN3 CA,ACH-000940,CVCL_0028,Uterus,POLE,Het,Missense,p.S30L,,Suppressor
933,AN3 CA,ACH-000940,CVCL_0028,Uterus,PTEN,Hom,Frameshift,p.R130fs,LoF,Suppressor
934,AN3 CA,ACH-000940,CVCL_0028,Uterus,SETD1B,Het,Frameshift,p.P749fs,LoF,Suppressor
935,AN3 CA,ACH-000940,CVCL_0028,Uterus,SMARCA4,Het,Missense,p.P1456L,,Suppressor
936,AN3 CA,ACH-000940,CVCL_0028,Uterus,TERT,Het,Missense,p.D848G,,Oncogene
937,AN3 CA,ACH-000940,CVCL_0028,Uterus,TP53,Het,Missense,p.G389W,,Suppressor
938,AN3 CA,ACH-000940,CVCL_0028,Uterus,TP53,Het,Missense,p.R213Q,LoF,Suppressor
939,AN3 CA,ACH-000940,CVCL_0028,Uterus,TP53,Het,Frameshift,p.S90fs,LoF,Suppressor
940,AN3 CA,ACH-000940,CVCL_0028,Uterus,WNK2,Het,Missense,p.P702S,,Suppressor
941,AN3 CA,ACH-000940,CVCL_0028,Uterus,ZFHX3,Het,Frameshift,p.R1893fs,LoF,Suppressor
942,NCI-H2347,ACH-000875,CVCL_1550,Lung,B2M,Hom,Stopgain,p.Q28*,LoF,Suppressor
943,NCI-H2347,ACH-000875,CVCL_1550,Lung,EP300,Het,Missense,p.V5L,,Suppressor
944,NCI-H2347,ACH-000875,CVCL_1550,Lung,KRAS,Het,Missense,p.L19F,GoF,Oncogene
945,NCI-H2347,ACH-000875,CVCL_1550,Lung,NF1,Het,Missense,p.H31L,LoF,Suppressor
946,NCI-H2347,ACH-000875,CVCL_1550,Lung,NRAS,Hom,Missense,p.Q61R,GoF,Oncogene
947,NCI-H2347,ACH-000875,CVCL_1550,Lung,TP53,Hom,Splice_site,p.T125T,LoF,Suppressor
948,NCI-H2347,ACH-000875,CVCL_1550,Lung,TP53,Hom,Synonymous_splicing,Thr125Thr,,Suppressor
949,EKVX,ACH-000706,CVCL_1195,Lung,SMARCA4,Hom,Stopgain,p.Q418*,LoF,Suppressor
950,EKVX,ACH-000706,CVCL_1195,Lung,STK11,Hom,Missense,p.S216F,LoF,Suppressor
951,EKVX,ACH-000706,CVCL_1195,Lung,TP53,Hom,Stopgain,p.E204*,LoF,Suppressor
952,EKVX,ACH-000706,CVCL_1195,Lung,VHL,Het,Missense,p.S111I,,Suppressor
953,NCI-H2087,ACH-000841,CVCL_1524,Lung,ATM,Het,Missense,p.E848Q,,Suppressor
954,NCI-H2087,ACH-000841,CVCL_1524,Lung,ATM,Het,Missense,p.L2965F,LoF,Suppressor
955,NCI-H2087,ACH-000841,CVCL_1524,Lung,BRAF,Het,Missense,p.L597V,GoF,Oncogene
956,NCI-H2087,ACH-000841,CVCL_1524,Lung,MYC,,Gain,GAIN,GoF,Oncogene
957,NCI-H2087,ACH-000841,CVCL_1524,Lung,MYC,Het,Missense,p.E54K,,Oncogene
958,NCI-H2087,ACH-000841,CVCL_1524,Lung,NRAS,Het,Missense,p.Q61K,GoF,Oncogene
959,NCI-H2087,ACH-000841,CVCL_1524,Lung,PRDM2,Hom,Missense,p.P619S,,Suppressor
960,NCI-H2087,ACH-000841,CVCL_1524,Lung,RB1,Het,Splice_site,,LoF,Suppressor
961,NCI-H2087,ACH-000841,CVCL_1524,Lung,TP53,Hom,Missense,p.V157F,LoF,Suppressor
962,A-172,ACH-000558,CVCL_0131,CNS/Brain,ABL1,,Fusion,ABL1-CBFB,,Oncogene
963,A-172,ACH-000558,CVCL_0131,CNS/Brain,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
964,A-172,ACH-000558,CVCL_0131,CNS/Brain,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
965,A-172,ACH-000558,CVCL_0131,CNS/Brain,PTEN,Hom,Deletion,DEL,LoF,Suppressor
966,A-172,ACH-000558,CVCL_0131,CNS/Brain,RB1,Het,Missense,p.V852L,,Suppressor
967,hTERT-HPNE,,CVCL_C466,Pancreas,TERT,,Transgene,,,Oncogene
968,NCI-H23,ACH-000900,CVCL_1547,Lung,ATM,Hom,Missense,p.Q1919P,LoF,Suppressor
969,NCI-H23,ACH-000900,CVCL_1547,Lung,KMT2D,Het,Missense,p.G3465V,,Suppressor
970,NCI-H23,ACH-000900,CVCL_1547,Lung,KMT2D,Het,Missense,p.S4328T,,Suppressor
971,NCI-H23,ACH-000900,CVCL_1547,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
972,NCI-H23,ACH-000900,CVCL_1547,Lung,MYC,,Gain,GAIN,GoF,Oncogene
973,NCI-H23,ACH-000900,CVCL_1547,Lung,PMS2,Het,Missense,p.E491K,,Suppressor
974,NCI-H23,ACH-000900,CVCL_1547,Lung,SMARCA4,Hom,Stopgain,p.1566_1567KE>N*,LoF,Suppressor
975,NCI-H23,ACH-000900,CVCL_1547,Lung,STK11,Hom,Stopgain,p.W332*,LoF,Suppressor
976,NCI-H23,ACH-000900,CVCL_1547,Lung,TP53,Hom,Missense,p.M246I,LoF,Suppressor
977,NCI-H1792,ACH-000496,CVCL_1495,Lung,CDKN2A,Het,Stopgain,p.W110*,LoF,Suppressor
978,NCI-H1792,ACH-000496,CVCL_1495,Lung,KRAS,Het,Missense,p.G12C,GoF,Oncogene
979,NCI-H1792,ACH-000496,CVCL_1495,Lung,MYC,,Gain,GAIN,GoF,Oncogene
980,NCI-H1792,ACH-000496,CVCL_1495,Lung,SOS1,,Gain,GAIN,GoF,Oncogene
981,NCI-H1792,ACH-000496,CVCL_1495,Lung,TP53,Hom,Splice_site,,LoF,Suppressor
982,NCI-H2122,ACH-000311,CVCL_1531,Lung,CDKN2A,,Deletion,DEL,LoF,Suppressor
983,NCI-H2122,ACH-000311,CVCL_1531,Lung,CDKN2B,Hom,Deletion,DEL,LoF,Suppressor
984,NCI-H2122,ACH-000311,CVCL_1531,Lung,KRAS,Hom,Missense,p.G12C,GoF,Oncogene
985,NCI-H2122,ACH-000311,CVCL_1531,Lung,MYC,,Gain,GAIN,GoF,Oncogene
986,NCI-H2122,ACH-000311,CVCL_1531,Lung,STK11,Hom,Frameshift,p.P281fs,LoF,Suppressor
987,NCI-H2122,ACH-000311,CVCL_1531,Lung,TP53,Het,Missense,p.C176F,LoF,Suppressor
988,NCI-H2122,ACH-000311,CVCL_1531,Lung,TP53,Het,Missense,p.Q16L,LoF,Suppressor
989,NCI-H2030,ACH-000521,CVCL_1517,Lung,KRAS,Hom,Missense,p.G12C,GoF,Oncogene
990,NCI-H2030,ACH-000521,CVCL_1517,Lung,POLE,Hom,Missense,p.S780L,,Suppressor
991,NCI-H2030,ACH-000521,CVCL_1517,Lung,STK11,Hom,Stopgain,p.E317*,LoF,Suppressor
992,NCI-H2030,ACH-000521,CVCL_1517,Lung,STK11,Hom,Missense,p.E357K,,Suppressor
993,NCI-H2030,ACH-000521,CVCL_1517,Lung,STK11,Hom,Missense,p.M392I,,Suppressor
994,NCI-H2030,ACH-000521,CVCL_1517,Lung,TP53,Hom,Missense,p.G262V,LoF,Suppressor
995,LOX-IMVI,ACH-000750,CVCL_1381,Skin,ARID1A,Het,Stopgain,p.Q1212*,LoF,Suppressor
996,LOX-IMVI,ACH-000750,CVCL_1381,Skin,BRAF,Het,Missense,p.V600E,GoF,Oncogene
997,LOX-IMVI,ACH-000750,CVCL_1381,Skin,CDKN2A,Hom,Deletion,DEL,LoF,Suppressor
998,LOX-IMVI,ACH-000750,CVCL_1381,Skin,NF1,Het,Stopgain,p.Q1174*,LoF,Suppressor
999,LOX-IMVI,ACH-000750,CVCL_1381,Skin,TERT,,Promoter,1-124C>T,GoF,Oncogene