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Dataset Card for UNI2-h-DSS

This dataset card provides the details of the UNI2-h-DSS dataset used in Path-PKT (Liu et al., 2025). DSS refers to Disease-Specific Survival, which is a typical event of interest in survival analysis.

Requesting Access

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Dataset Description

UNI2-h-DSS is a dataset used in the Path-PKT study. It is curated for the study of WSI-based cancer prognosis. It has

  • 13 datasets for cancer-specific training, with 7,268 patients and 8,818 WSIs in total;
  • 13 datasets (each corresponding to one rare tumor disease) for algorithm validation, with 1,922 patients and 2,370 WSIs.

Content

  • data-splits-for-cancer-specific-training: Data split files (5-fold cross-validation) for 13 cancer datasets used in cancer-specific training.
  • follow-up-labels-of-rare-tumor-datasets: DSS follow-up labels of all patients in 13 rare tumor datasets.
  • Distributed 'CSV' files: they contain the information of patient_id, slide_id, censorship status, and DSS follow-up time associated with all cancer patients.

Original WSIs can be downloaded at TCGA GDC portal; The image features extracted by UNI2-h (Chen et al., 2024) can be accessed here.

Information Summary

Usage

Following authentication, the datasets can be loaded manually at this website or in the following ways:

Install huggingface-cli and log into your account

pip install -U "huggingface_hub[cli]"
huggingface-cli login

Download datasets

local_dir=/path/to/local_dir
huggingface-cli download yuukilp/UNI2-h-DSS --repo-type dataset --local-dir $local_dir

Contact

For any additional questions or comments, please contact Pei Liu ([email protected]).

How to Cite

Anyone who uses this dataset should consider cite the following works:

Path-PKY study (curating 26 cancer-specific datasets with DSS follow-up labels for cancer prognosis research):

@misc{liu2025pathpkt,
      title={Towards Understanding and Harnessing the Transferability of Prognostic Knowledge in Computational Pathology}, 
      author={Pei Liu and Luping Ji and Jiaxiang Gou and Xiangxiang Zeng},
      year={2025},
      eprint={2508.13482},
      archivePrefix={arXiv},
      url={https://arxiv.org/abs/2508.13482}, 
}

Original TCGA datasets (providing pan-cancer cohorts):

@article{weinstein2013cancer,
  title={The cancer genome atlas pan-cancer analysis project},
  author={Weinstein, John N and Collisson, Eric A and Mills, Gordon B and Shaw, Kenna R and Ozenberger, Brad A and Ellrott, Kyle and Shmulevich, Ilya and Sander, Chris and Stuart, Joshua M},
  journal={Nature genetics},
  volume={45},
  number={10},
  pages={1113--1120},
  year={2013},
  publisher={Nature Publishing Group}
}

Pretrained UNI2-h models (for image feature extraction):

@article{chen2024uni,
  title={Towards a General-Purpose Foundation Model for Computational Pathology},
  author={Chen, Richard J and Ding, Tong and Lu, Ming Y and Williamson, Drew FK and Jaume, Guillaume and Chen, Bowen and Zhang, Andrew and Shao, Daniel and Song, Andrew H and Shaban, Muhammad and others},
  journal={Nature Medicine},
  publisher={Nature Publishing Group},
  year={2024}
}
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