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2022/01/05 グランザイムB抑制剤 (57)【要約】 【課題】効果の高いグランザイムB抑制剤を提供する。 【解決手段】ゲンノショウコエキスを有効成分として含有する。 【選択図】なし
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-6988016/15/ja" }
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【特許請求の範囲】 【請求項1】 ゲンノショウコエキスを有効成分として含有する、グランザイムB抑制剤。 【請求項2】 ゲンノショウコエキスを1〜100μg/mL含有する、請求項1に記載のグランザイムB抑制剤。 【請求項3】 ゲンノショウコエキスを1.8〜55μg/mL含有する、請求項2に記載のグランザイムB抑制剤。 【請求項4】 ゲンノショウコエキスを18〜55μg/mL含有する、請求項3に記載のグランザイムB抑制剤。 【請求項5】 グランザイムB抑制作用を有する1種以上の植物エキスをさらに含有する、請求項1から4のいずれか一項に記載のグランザイムB抑制剤。 【請求項6】 前記植物エキス及び前記ゲンノショウコエキスを1:1〜1:4の質量比で含有する、請求項5に記載のグランザイムB抑制剤。 【請求項7】 前記植物エキスが、ザクロ果皮エキス、イエローヒマラヤンラズベリー根エキス、ユーカリエキス、ワレモコウエキス、イロハモミジ葉エキス、シモツケソウエキス、ハマメリスエキス、バラエキス、アボガドエキス、テンチャエキス、メマツヨイグサ抽出液、ウーロン茶エキス、カシア樹皮エキス、ユキノシタエキス、メリッサエキス、トルメンチラエキス、ダマスクバラ花エキス、ヨモギエキス、ヒキオコシエキス、コンフリーエキス、オトギリソウエキス、セイヨウハッカエキス、ブドウ葉エキス、シナノキエキス、エイジツエキス、ビワ葉エキス、海藻エキス、シャクヤクエキス、ドクダミエキス、サンザシエキス、シソエキス、ラベンダーエキス、ノバラエキス、アセンヤクエキス、サガラメエキス、ボタンエキス、アスパラサスリネアリスエキス、カンゾウ抽出末及びクララエキスからなる群から選択される、請求項5又は6に記載のグランザイムB抑制剤。 【請求項8】 前記植物エキスの少なくとも1種が、オトギリソウエキス及びテンチャエキスからなる群から選択される、請求項7に記載のグランザイムB抑制剤。 【請求項9】 グランザイムB抑制が、グランザイムB遺伝子の発現抑制である、請求項1から8のいずれか一項に記載のグランザイムB抑制剤。 【請求項10】 グランザイムB抑制が、グランザイムBの活性阻害である、請求項1から8のいずれか一項に記載のグランザイムB抑制剤。 【請求項11】 グランザイムB抑制が、グランザイムB遺伝子の発現抑制及びグランザイムBの活性阻害である、請求項1から8のいずれか一項に記載のグランザイムB抑制剤。 【請求項12】 請求項1から11のいずれか一項に記載のグランザイムB抑制剤のみからなる、化粧料組成物。 【請求項13】 ゲンノショウコエキスを有効成分として含有する、コラーゲン分解抑制剤。 【請求項14】 ゲンノショウコエキスを1〜100μg/mL含有する、請求項13に記載のコラーゲン分解抑制剤。 【請求項15】 ゲンノショウコエキスを1.8〜55μg/mL含有する、請求項14に記載のコラーゲン分解抑制剤。 【請求項16】 ゲンノショウコエキスを18〜55μg/mL含有する、請求項15に記載のコラーゲン分解抑制剤。 【請求項17】 コラーゲン分解抑制作用を有する1種以上の植物エキスをさらに含有する、請求項13から16のいずれか一項に記載のコラーゲン分解抑制剤。 【請求項18】 前記植物エキス及び前記ゲンノショウコエキスを1:1〜1:4の質量比で含有する、請求項17に記載のコラーゲン分解抑制剤。 【請求項19】 前記植物エキスが、ザクロ果皮エキス、イエローヒマラヤンラズベリー根エキス、ユーカリエキス、ワレモコウエキス、イロハモミジ葉エキス、シモツケソウエキス、ハマメリスエキス、バラエキス、アボガドエキス、テンチャエキス、メマツヨイグサ抽出液、ウーロン茶エキス、カシア樹皮エキス、ユキノシタエキス、メリッサエキス、トルメンチラエキス、ダマスクバラ花エキス、ヨモギエキス、ヒキオコシエキス、コンフリーエキス、オトギリソウエキス、セイヨウハッカエキス、ブドウ葉エキス、シナノキエキス、エイジツエキス、ビワ葉エキス、海藻エキス、シャクヤクエキス、ドクダミエキス、サンザシエキス、シソエキス、ラベンダーエキス、ノバラエキス、アセンヤクエキス、サガラメエキス、ボタンエキス、アスパラサスリネアリスエキス、カンゾウ抽出末及びクララエキスからなる群から選択される、請求項17又は18に記載のコラーゲン分解抑制剤。 【請求項20】 前記植物エキスの少なくとも1種が、オトギリソウエキス及びテンチャエキスからなる群から選択される、請求項19に記載のコラーゲン分解抑制剤。 【請求項21】
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-6988016/15/ja" }
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【請求項20】 前記植物エキスの少なくとも1種が、オトギリソウエキス及びテンチャエキスからなる群から選択される、請求項19に記載のコラーゲン分解抑制剤。 【請求項21】 コラーゲン分解抑制が、グランザイムB遺伝子の発現抑制である、請求項13から20のいずれか一項に記載のコラーゲン分解抑制剤。 【請求項22】 コラーゲン分解抑制が、グランザイムBの活性阻害である、請求項13から20のいずれか一項に記載のコラーゲン分解抑制剤。 【請求項23】 コラーゲン分解抑制が、グランザイムB遺伝子の発現抑制及びグランザイムBの活性阻害である、請求項13から20のいずれか一項に記載のコラーゲン分解抑制剤。
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-6988016/15/ja" }
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2021/07/29 キュウリ、ナス及びカタツムリの混合抽出物を有効成分として含む脱毛防止又は発毛促進用組成物 (57)【要約】 本発明は、キュウリ、ナス及びカタツムリの混合抽出物を有効成分として含む脱毛防止又は発毛促進用組成物に関する。本発明に係る組成物は、キュウリ、ナス及びカタツムリの混合抽出物を有効成分として含むことによって、新しい毛穴の誘導及び毛髪成長の維持に必須的な役割をするものとして知られている真皮乳頭細胞において肝細胞成長因子であるHGF、角質形成細胞因子であるKGF及びインシュリン様成長因子であるIGF−Iの発現を増加させ、6週齢のC57BL/6マウスの毛を除去した後、毛髪成長効果の確認試験でミノキシジルと同等な毛髪生長効果を示し、人を対象にした臨床試験でも脱毛症の改善効果が確認されたので、脱毛防止又は発毛促進用化粧料組成物及び皮膚外用薬学組成物として有用に利用可能である。 【選択図】 図1 【特許請求の範囲】 【請求項1】 キュウリ、ナス及びカタツムリの混合抽出物を有効成分として含む脱毛防止又は発毛促進用組成物。 【請求項2】 前記組成物は、側柏葉及び苦参の混合抽出物をさらに含むことを特徴とする、請求項1に記載の脱毛防止又は発毛促進用組成物。 【請求項3】 前記組成物は、乾地黄、乾薑、当帰、旱蓮草、白首烏、粟及び玄米から選ばれるいずれか一つ以上の抽出物をさらに含むことを特徴とする、請求項2に記載の脱毛防止又は発毛促進用組成物。 【請求項4】 前記組成物は、魚腥草及び甘草から選ばれるいずれか一つ以上の抽出物をさらに含むことを特徴とする、請求項3に記載の脱毛防止又は発毛促進用組成物。 【請求項5】 前記組成物は化粧料組成物であることを特徴とする、請求項1乃至請求項4のいずれか1項に記載の組成物。 【請求項6】 前記組成物は皮膚外用薬学組成物であることを特徴とする、請求項1乃至請求項4のいずれか1項に記載の組成物。 【請求項7】 前記組成物は健康機能食品用組成物であることを特徴とする、請求項1乃至請求項4のいずれか1項に記載の組成物。
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-7388782/15/ja" }
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2021/07/08 皮膚支帯改善剤 (57)【要約】 【課題】皮膚支帯成分であるタンパク質の発現量を増加させる作用を有する、新規な皮膚支帯改善剤を提供する。 【解決手段】タンパク質の発現量を増加させる作用を有する植物抽出物を添加する。 【選択図】なし
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-7257437/15/ja" }
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"【特許請求の範囲】 【請求項1】 細胞における、ミメカン(Mime(...TRUNCATED)
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-7257437/15/ja" }
[0.032060038298368454,-0.0017205842304974794,0.07024729996919632,0.03909340128302574,0.0032308148220(...TRUNCATED)
"reticulata)、マメ科(Fabaceae)アスパラサス属((...TRUNCATED)
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-7257437/15/ja" }
[0.02448284812271595,0.0023513175547122955,0.01849665865302086,0.0334060862660408,0.0320832952857017(...TRUNCATED)
"2021/03/01\n化粧料\n(57)【要約】 【課題】可視光線の長波長領域の透過、お(...TRUNCATED)
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-7464363/15/ja" }
[0.02631915919482708,0.010953046381473541,-0.0038614324294030666,0.011897078715264797,0.040809482336(...TRUNCATED)
"2020/07/16\nD-chiro-イノシトールを含む外用組成物\n(57)【要約】 (...TRUNCATED)
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-7425536/15/ja" }
[0.013586148619651794,-0.0018188557587563992,0.02154489792883396,0.05057768151164055,-0.004010957200(...TRUNCATED)
"2020/05/14\nセラミド調整剤\n(57)【要約】 【課題】セラミダーゼ阻害効果に(...TRUNCATED)
{ "source": "https://www.j-platpat.inpit.go.jp/c1801/PU/JP-6948654/15/ja" }
[0.06940615177154541,0.04936785250902176,0.026118291541934013,0.06101404130458832,0.0140118217095732(...TRUNCATED)
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