Consider the following premises. t_4 or q. q -> r_11. p_4 <-> r_11. r_16 -> r_11. ~t_4 or r_16. Can we infer ~p_4 from them?
 From t_4 or q, ~t_4 or r_16 we can infer q or r_16. From q -> r_11, r_16 -> r_11, q or r_16 we can infer r_11. From p_4 <-> r_11 we can infer r_11 -> p_4. Finally, from r_11 -> p_4, r_11 we can infer p_4, which contradicts ~p_4. Therefore, the answer is no.