Consider the following premises. forall x_12: W_4(x_12) and R(x_12). forall x_12: S(x_12) -> ~W_4(x_12). s -> S(i). Can we infer ~s from them?
 From forall x_12: W_4(x_12) and R(x_12) we can infer forall x_12: W_4(x_12). From forall x_12: S(x_12) -> ~W_4(x_12), forall x_12: W_4(x_12) we can infer forall x_12: ~S(x_12). From forall x_12: ~S(x_12) we can infer ~S(i). Finally, from s -> S(i), ~S(i) we can infer ~s. Therefore, the answer is yes.