Consider the following premises. r -> R_17(a_17). ~S_17(a_17). s -> r. r -> s. forall x_17: R_17(x_17) -> S_17(x_17). Can we infer ~s from them?
 From forall x_17: R_17(x_17) -> S_17(x_17) we can infer R_17(a_17) -> S_17(a_17). From r -> R_17(a_17), R_17(a_17) -> S_17(a_17) we can infer r -> S_17(a_17). From r -> S_17(a_17), ~S_17(a_17) we can infer ~r. From r -> s, s -> r we can infer r <-> s. Finally, from r <-> s, ~r we can infer ~s. Therefore, the answer is yes.