Questions 18-20 are based on the following data.
The generalized events in DNA replication can be depicted by the following flowchart:
Double helix $\rightarrow$ Nicking of a strand $\rightarrow$ Unwinding $\rightarrow$ Destabilization and relief of pressure $\rightarrow$ Initiation $\rightarrow$ Elongation $\rightarrow$ Closing of nicks
Between which two steps would the enzyme DNA polymerase be used?
A. Double helix $\rightarrow$ Nicking of a strand
B. Nicking of a strand $\rightarrow$ Unwinding
C. Initiation $\rightarrow$ Elongation
D. Elongation $\rightarrow$ Closing of nicks
Choose A, B, C or D as your solution.
The correct answer is C. Chain growth in DNA replication is initiated by a primase and is extended by a DNA polymerase. Thus the enzyme acting between Initiation $\rightarrow$ Elongation is DNA polymerase.