Consider the following premises. R_16(a_16) -> p. forall x_16: ~R_16(x_16). p -> R_16(a_16). Can we infer ~p or q from them?
 From forall x_16: ~R_16(x_16) we can infer ~R_16(a_16). From p -> R_16(a_16), R_16(a_16) -> p we can infer p <-> R_16(a_16). From p <-> R_16(a_16), ~R_16(a_16) we can infer ~p. Finally, from ~p we can infer ~p or q. Therefore, the answer is yes.