All I did was check the Wikipedia page [1] for IOMMU-supporting hardware, and I needed to upgrade my CPU from a Phenom to FX. You don&#x27;t need special audio, just the right motherboard (chipset specifically) and CPU. If you do PCI passthrough, it doesn&#x27;t matter if the Linux host can talk to the card, the guest OS will take care of everything.<p>Otherwise, check the forums. This has been done many times over the years, and there&#x27;s no shortage of existing information.<p>[1] <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;List_of_IOMMU-supporting_hardware" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;List_of_IOMMU-supporting_hardw...</a>