There are many things you don&#x27;t know and don&#x27;t know you don&#x27;t know, that is complicated to explain. I, for sure, am ignorant of a lot too, but at least I know that estimating heritability on the occurrence of bipolar disorder doesn&#x27;t prove that these disorders are &quot;caused&quot; (you used this word, while the article doesn&#x27;t) by genetic factors.