Of course you can interact with two monitors at once. I do it every day.<p>My current standing desk setup is an MBPR15 on top of a wine case on my desk, with a ViewSonic 24&quot; 4K display to the left, hanging in portrait mode on the Amazon Basics version of an Ergotron arm. Best dev rig I&#x27;ve ever had!<p>Quite often I&#x27;ll put docs and references on the external monitor while I write code in Visual Studio or IntelliJ on the Mac&#x27;s display. This works especially well with the monitor in portrait mode.<p>Then I leave the mouse cursor over on the external display and use two-finger scrolling there, while using the keyboard in the editor window.<p>If this isn&#x27;t interacting with two monitors at once, I don&#x27;t know what is. And it&#x27;s a huge improvement over a single monitor.