&gt; construct a roadmap<p>I just don&#x27;t understand what this means here.  Cloning a gene and expressing it in e.coli is something that has been routine for <i>decades</i>. Literally.  These simple experiments won&#x27;t provide a roadmap to do anything that we haven&#x27;t known how to do for a long time.  It&#x27;s like a crowdsourcing project to raise money to write a &quot;hello world&quot; program.  Seriously.<p>Open-ness is great.  But &quot;meaningful contributions&quot; are generally made at the cutting edge of scientific research.  The experiments described are nipping at the heels of science that was worked-out in the early 80s, so I fail to see how a meaningful contribution will be made here.  Open source is great, but making headway in drug discovery or development is a Hard Problem and this doesn&#x27;t strike me as a serious effort.  Just my two cents.