I can&#x27;t naively hope that very high performance (exascale) computing helps finding the right theories here. But I do hope that people don&#x27;t waste time digging in the wrong direction. Facing complexity is better than not being aware of it.<p>ps: I hope though, in the case of non mental disorders, that finer and cheaper technology allow for preemptive discovery, continuous monitoring and non invasive therapies.