&quot;He said this month new data indicate that the biggest 
increases in marijuana hospitalizations have been seen among out-of-staters, who might be naive about the drug’s effects.&quot;<p>Colorado is a high-altitude state, and dehydration is a common problem. MJ is famously dehydrating (&quot;cottonmouth&quot;). Combine that with alcohol consumption and you&#x27;ve got a trifecta. People who live here are both acclimated to the altitude and typically familiar with the dehydration issue and tend to take precautions. Out-of-staters are likely not acclimated and not used to living in an arid environment.<p>If you&#x27;re coming to CO and you want to smoke, remember to hydrate. 2 liters a day, minimum.<p>As an anecdote I have a friend who works in an ER. He contends that most of the cases he sees on the weekends are dehydration (not necessarily from MJ, just overall).