I work at a major (the biggest?) telecom equipment provider. For a couple of years, I've been doing ad-hoc Python scripts (say, 3000+ lines) to interact with network nodes, based on customer requests. So yes, there is room for professional, non-web related Python. I try to push the language for more developments, but it's hard to convince managers. I prefer the tools I make to the standard, corporate fat applications we sell for millions. If anyone is hiring on those skills, I'll be glad to hear offers.