Consistency is the most difficult part; burn-out is the enemy of consistency, and the bedfellow of overzealous beginnings.  I know a lot of people who tried to go from zero to 60 in a week, and after 7 days straight of running &#38; weightlifting, they gave up for another six months.<p>Generally, the longer it takes you to lose weight, the longer it will stay off.  If you're losing lots of pounds over the first day, or week, or even month, be careful of burnout!<p>What finally worked for me was starting with 2 days of cardio per week for 2 weeks, then 2 days of cardio + 2 days of weightlifting per week for 2 weeks, then 3 cardio + 2 weights for 2 weeks, then 3 cardio + 3 weights for 2 weeks.  After those 60 days, I had a routine that felt comfortable and was more difficult to avoid than maintain!