I've noticed that the biggest problem for my hands, wrists, etc., is using a trackpad or mouse.  The more my hands just stay on the keyboard the better they feel.<p>One nice thing about typing on the netbook is that the front part (in front of the keyboard where your palms tend to rest) is very short and this prevents me from the bad habit of resting my wrists... since the netbook is light it also prevents the bad habit of exerting downward wrist pressure to keep the laptop balanced.<p>I think it's good to do whatever works,... I was skeptical that I'd like the netbook, but I haven't used my full size laptop in months.