&gt; Whole lot of speculation in this article. I would guess more people know about the placebo effect in the U.S., than they did 20 years ago? Twenty years ago, we didn&#x27;t question the efficacy of these drugs? Everyone I know now is very leery of any claims by drug companies, and their Wonder Drug.<p>I would argue this is now the case in most of the developed world, not just the US.