HPC also use OS Bypass so the plan9 team, who develop for Blue Gene and other large clusters, worked on currying system calls to maximize throughput<p><a href="http:&#x2F;&#x2F;4e.iwp9.org&#x2F;papers&#x2F;usecsys.pdf" rel="nofollow">http:&#x2F;&#x2F;4e.iwp9.org&#x2F;papers&#x2F;usecsys.pdf</a>