A comprehensive test looking at the BRCAs may deeply sequence sequence the entire gene(s); spanning around 150 thousand base pairs. You&#x27;d not only want to look for SNPs, but novel SNVs, and various structural variants (SVs) and copy-number variants (CNVs). I don&#x27;t know the most common class of mutations for BRCA1 and 2, so it may be the case that a smaller, cheaper panel could be nearly as effective as well.