I&#x27;m sure that the doubts in 1990 were strongly affected by the HGP as carried out under the DOE days.<p>I&#x27;m sure the doubts in 1998 were based on different factors.<p>Internally, the HGP in 1998 considered themselves on track. Quoting from <a href="http:&#x2F;&#x2F;www.genome.gov&#x2F;10001475" rel="nofollow">http:&#x2F;&#x2F;www.genome.gov&#x2F;10001475</a> :<p>&gt; The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-1998. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, two years ahead of previous projections. In the course of completing the sequence, a &quot;working draft&quot; of the human sequence will be produced by the end of 2001.