So many gut microbiome variables, so many neurologic variables in the brain, so many type 1 errors calling out from the data in seductive whispers &quot;publish me...&quot;. While preliminary research is curious, I predict that more medium-term progress will be a result of throwing fecal transplant at many disorders, it will work for a few (like abx-resistant C diff), and it will not work for others even though people will claim it does. and then people will make up biologic stories about how things interact with decreasingly hand wavy (inflammation!) theories that may or may not be practically testable depending on the number of working parts involved. That&#x27;s how medicine works a lot of the time, anyways.