There is tool to prepare a guix package from PyPi but because of the naming issues it can&#x27;t use PyPi directly.<p>Yes once package is built, it&#x27;s cached.<p>edit: the command name is `guix import pypi` <a href="http:&#x2F;&#x2F;www.gnu.org&#x2F;software&#x2F;guix&#x2F;manual&#x2F;guix.html#Invoking-guix-import" rel="nofollow">http:&#x2F;&#x2F;www.gnu.org&#x2F;software&#x2F;guix&#x2F;manual&#x2F;guix.html#Invoking-g...</a>