1Password stores its encrypted data &#x27;offline&#x27;, so 2FA does not make sense for their product.<p>Even with LastPass offering 2FA, its just that, authentication, its not used as part of the encryption&#x2F;decryption process (I did read somewhere it helps with your local cached copy, but it doesn&#x27;t effect the copy stored on their servers)<p>If you wanted to use your YubiKey with 1Password, you could set a static password and &#x27;split&#x27; your master password (half you remember, the other half is keyed in by the YubiKey)