Preliminary evidence has been found in humans, looking at the other end of the spectrum with hypotension.<p><a href="http:&#x2F;&#x2F;online.liebertpub.com&#x2F;doi&#x2F;10.1089&#x2F;neu.2014.3778" rel="nofollow">http:&#x2F;&#x2F;online.liebertpub.com&#x2F;doi&#x2F;10.1089&#x2F;neu.2014.3778</a><p>We are now looking at the hypertension relationship in humans, as well as mechanistic studies in rats.