Related: “Eroom’s Law”[1], coined in this Nature paper: <a href="http:&#x2F;&#x2F;www.nature.com&#x2F;nrd&#x2F;journal&#x2F;v11&#x2F;n3&#x2F;full&#x2F;nrd3681.html" rel="nofollow">http:&#x2F;&#x2F;www.nature.com&#x2F;nrd&#x2F;journal&#x2F;v11&#x2F;n3&#x2F;full&#x2F;nrd3681.html</a> which states that the cost of discovering a new drug has been increasing exponentially for 60 years.<p>Obligatory log graph: <a href="http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;wp-content&#x2F;uploads&#x2F;sites&#x2F;2&#x2F;2015&#x2F;04&#x2F;RD-trend.png" rel="nofollow">http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;wp-content&#x2F;uploads&#x2F;site...</a><p>Some discussion at the “In The Pipeline” blog:
<a href="http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;archives&#x2F;2012&#x2F;03&#x2F;08&#x2F;erooms_law" rel="nofollow">http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;archives&#x2F;2012&#x2F;03&#x2F;08&#x2F;ero...</a>
<a href="http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;archives&#x2F;2012&#x2F;03&#x2F;14&#x2F;the_blackian_demon_of_drug_discovery" rel="nofollow">http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;archives&#x2F;2012&#x2F;03&#x2F;14&#x2F;the...</a>
<a href="http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;archives&#x2F;2012&#x2F;03&#x2F;12&#x2F;the_brute_force_bias" rel="nofollow">http:&#x2F;&#x2F;blogs.sciencemag.org&#x2F;pipeline&#x2F;archives&#x2F;2012&#x2F;03&#x2F;12&#x2F;the...</a><p>[1] You may now groan.