&gt;  You still have permanently increased insulin resistance and you must stay on your exercise and diet to prevent it getting worse.<p>Dr. Taylor&#x27;s research, along with other research currently being done, is demonstrating that insulin resistance is <i>not</i> permanent as was once believed.  The problem is, as ollysb noted below, getting people to make the lifestyle changes necessary and stick to them.  Most people are not willing and able to make the changes required to keep the disease from progressing, let alone increase their insulin sensitivity again.