Newton&#x27;s theory is a simple three-variable model that describes a simple power law relationship between them. Holy fuck, would it be fantastic if ANY ASPECT of biochemistry or biology could be modeled with such a simple description. As a biologist I can tell you this is very far from the case. This is a huge problem with the field of biology, actually, that the models (and ideas of complexity) we have to bring to bear were developed in physics where the parametrizations are simple and clean and provide high predictive value.<p>This math simply doesn&#x27;t work when you throw it against a biology problem. Precise formulations don&#x27;t exist when you&#x27;re dealing with, say, the interactions between two 100-amino acid folded proteins. Physics operates on simple rules that work everywhere; biology operates on complex rule sets that are often broken. The math is just not up to snuff, here.