While I agree with the criticism of publication, there have been 7 Nobel prize winners due to self-experimentation. On top of that:<p><i>In a remarkable 89% of instances, the self-experiments obtained positive results in support of a hypothesis or valuable data that had been sought. In the remaining studies in which results were either negative or inconclusive, some of the negative results could be viewed as beneficial in directing investigators into more fruitful avenues of research.</i><p><a href="http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3298919&#x2F;" rel="nofollow">http:&#x2F;&#x2F;www.ncbi.nlm.nih.gov&#x2F;pmc&#x2F;articles&#x2F;PMC3298919&#x2F;</a>