So the use case here is particularly interesting.<p>Most of the answers are talking about spaceflight,  because it is one of the only radioactive environments that has a particle distribution that can be effectively fought.<p>Most earthbound environments have particle distributions that are practically unsolvable in software,  and should instead be solved by using mechanical and noise tolerant analogue methods of sensing and manipulating and then massively shielding your computation (normally by controlling from a different building).<p>*Note.  By particle distribution I am refferring to both rate and charge