The typical way to picture the universe is like the surface of an expanding balloon, a 2-manifold which happens to be embedded in 3-space. If you picture galaxies as spots on the balloon, there&#x27;s no &quot;last&quot; galaxy, they&#x27;re all roughly equidistant from their neighbors.  Analogously, our Euclidean universe is thought of (in terms of noncompact spatial dimensions) as an expanding 3-manifold.  There&#x27;s no last galaxy there either.  However, if you include time, then at some point in the distant future there will be a last galaxy because old stars will all burn out or be sucked into black holes.  And further in the future protons will decay, so there will be no baryonic matter left, plus black holes will eventually evaporate.  Much sooner than that though, the continued expansion of spacetime means that galaxies will in time disappear over the expanding cosmological horizon, and future lifeforms will know nothing of the universe outside their own aging galaxies.  See:  <a href="https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Future_of_an_expanding_universe" rel="nofollow">https:&#x2F;&#x2F;en.wikipedia.org&#x2F;wiki&#x2F;Future_of_an_expanding_univers...</a>