I don&#x27;t see why pinprick testing would help; it&#x27;s not like a regular draw is that unpleasant (I went through a period of my life where I had two cylinders drawn every week).<p>The opposite problem exists with the tiny samples: blood like any other fluid, is not at all points identical at all times.  You can easily demonstrate this for yourself: go to the drug store and buy a cheap glucose meter and take a bunch of samples just around the same finger, much less different fingers.  You&#x27;ll see a surprising level of variation.  The larger samples of a conventional draw are shown to vary less.<p>They still vary (as the line you quote says) but less than the highly local samples.