Aging is a medical condition. The present approaches to dealing with it are expensive and terrible, which is to say therapies that are nothing more than patches or meddling with late-stage disease state without addressing root causes, and research that is focused on creating a full understanding of those disease states by working backwards. There are other approaches that look like they could be cheap and effective, which is to say repairing the consensus root causes of aging after the SENS model, the forms of change and damage found in old tissues and that are caused by normal operation of metabolism, not by some other form of damage.<p>Disruption is absolutely possible in this scenario. Replace the bad old expensive approach with the much better approach, while the old guard tell you how wrong you are all the way until their positions become untenable.<p>It wasn&#x27;t so many years ago that people were claiming SENS was nonsense. Now everyone agrees that, for example, senescent cell clearance, a part of SENS right from the outside, is great and extends life in mice, and human therapies should be developed to produce rejuvenation as a result of clearing these unwanted, damaging cells.<p>There are startups right now working on SENS and SENS-like approaches to repairing the damage that causes aging, technologies that can be realized for a fraction of the cost spent so far on mapping the biochemistry and genetics of metabolism and aging. That looks a lot like disruption under way to me.