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biology of prions Dr. Stanley Prusiner coined the term prion in 1982, which he defined as a small infectious pathogen containing protein but apparently lacking nucleic acid . The prion protein (PrP) is the critical component of these agents and may, in fact, be its exclusive constituent.
Scientists have found prions â abnormal proteins widely believed to cause a rare, brain-destroying disease â in the skin of 23 patients who had died from it, according to a study published on Wednesday.