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If something s getting on your nerves, it could make your wrist hurt. When the tunnel that surrounds the nerve between the wrist and thumb experiences pressure, you may develop carpal tunnel syndrome. The nerve controls sensations in the hand, so when pressure is put on it, the fingers and palm could tingle or burn.
Overuse problems. 1  Carpal tunnel syndrome is caused by pressure on a nerve (median nerve ) in the wrist. The symptoms include tingling, numbness, weakness, or pain of the fingers and hand. 2  Tendon pain is actually a symptom of tendinosis, a series of very small tears (microtears) in the tissue in or around the tendon.