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Typically referring to a measurement on an imaging study (xray, CT scan, MRI, ultrasound), sub-centimeter refers to a measurement less than 1 centimeter.
Subcentimeter pulmonary nodules seen on lung CT present very difficult interpretation problems. For small pulmonary nodules, CT morphology is quite nonspecific, no typical feature of malignancy is defined, and considerable error is associated in the density measurement (32).