Time Alignment of Signals. I discussed the idea of a time-alignment scheme in the article Delays, Delays, Delays. The idea is that signals which have a mechanical delay of some kind (gas transport time, for example) can be time-aligned with signals that have a lesser or no such delay by means of a âlogicalâ delay line inserted into all channels.
Telomeres, dynamic structures capping the ends of chromosomes, are composed of long arrays of repeated deoxyribonucleic acid (DNA) sequences accompanied by closely associated proteins. In most organisms, these repeats are maintained by the enzyme, telomerase.
Telomere dysfunction is the first sign that the telomeres are getting shorter in a person compared to the average telomere length in a comparable age group. This is not only important for aging, but also has clinical implications. The shorter telomeres are, the higher the risk for cardiovascular disease. Telomere length also provides prognostic information about the mortality risk (risk of dying) with type 2 diabetes and for many cancers.