In fact, degenerative arthritis is thought to involve the entire joint structure with erosion of articular cartilage, hypertrophy of bone at the margins of the affected joint, changes to the synovial membrane (i.e., joint lining), subchondral bone sclerosis, and involvement of the ligaments and periarticular muscles.
14 days: The bullseye rash of lyme disease takes about 14 days to show up. You could have an allergic reaction to a bug bite that will develop within a day. Infection from a bite, not lyme disease, starts getting worse after about 2-3 days.
Nov 15 (Reuters) - When the bulls-eye shaped rash of Lyme. disease reappears many months after treatment, the source is. almost certainly a new tick bite and not a resurgence of the. original infection, according to a U.S. study. The findings, which appeared in the New England Journal of.