Whether it is brand-new or years old, a mattress too soft for your comfort level may make for many restless nights. As long as the mattress is in good shape, there's no need to replace it to achieve the desired level of firmness.Instead, purchase a firm topper, slide a bed board beneath the mattress, or add extra support to the bed frame itself. sheet of plywood cut to the same size as the mattress offers support for a mattress that has lost some of its firmness. Slide the plywood between the mattress and box spring.
Human cells normally contain 23 pairs of chromosomes, for a total of 46 chromosomes in each cell (illustration). A change in the number of chromosomes can cause problems with growth, development, and function of the bodyâs systems.
Affected people have two copies of chromosome 21 plus extra material from chromosome 21 attached to another chromosome, resulting in three copies of genetic material from chromosome 21. Affected individuals with this genetic change are said to have translocation Down syndrome.In a very small percentage of cases, Down syndrome results from an extra copy of chromosome 21 in only some of the body's cells. In these people, the condition is called mosaic Down syndrome.wo copies of chromosome 21, one copy inherited from each parent, form one of the pairs. Chromosome 21 is the smallest human chromosome, spanning about 48 million base pairs (the building blocks of DNA) and representing 1.5 to 2 percent of the total DNA in cells.