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Inference: The Process. Inference is a mental process by which we reach a conclusion based on specific evidence. Inferences are the stock and trade of detectives examining clues, of doctors diagnosing diseases, and of car mechanics repairing engine problems. We infer motives, purpose, and intentions.
Abduction, or inference to the best explanation, is a method of reasoning in which one chooses the hypothesis that would, if true, best explain the relevant evidence. Abductive reasoning starts from a set of accepted facts and infers most likely, or best, explanations. The term abduction also sometimes only refers to the generation of hypotheses that explain observations or conclusions, but the former definition is more common both in philosophy and computing.