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RhoGAM is used for: Preventing certain blood problems that may occur during pregnancy or blood transfusion. It may also be used for other conditions as determined by your doctor. RhoGAM is an immunoglobulin (Ig), which contains antibodies to the Rho(D) antigen. Exactly how it works is unknown.
For every subsequent pregnancy after the first, RhoGAM will need to be administered at regular intervals, especially during the second half of the pregnancy. It is also extremely important for Rh-negative women to receive this injection after any miscarriage or abortion in order to avoid future pregnancy complications.