certificate of analysis. Definition. A document issued by a regulatory or quality assurance entity verifying the adherence to product specifications and standards of production of certain products such as food products and drugs. The certificate usually includes the actual test results performed on the product batch.
Tay-Sachs disease is caused by a mutation in the HEXA gene located on chromosome 15. Tay-Sachs follows an autosomal recessive pattern of inheritance. With the help of the diagram, identify which of the offspring will be an unaffected carrier.
Tay-Sachs, an inherited neurological disorder, is unusually common among French Canadians from east-ern Quebec. Two alleles are responsible, one being specific to the north shore of the St. Lawrence and the other to the south shore. This pattern of convergent evolution suggests the presence of a selection pressure limited to eastern Quebec.