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You can take levothyroxine either one hour before meals or two hours after eating and one hour before taking other meds and any vitamins and supplements but two hours before taking iron or calcium. Source(s): I'm a nurse. Nope, your supposed to take it on an empty stomach, then eat an hour or so after you take it.
I have been taking levothyroxine for 4 months now. Will I see any boost in my metabolism soon? I have been trying to lose weight, and can only seem to take of pounds (5 in 9 months) by doing excessive cardio (2 hours per day). I am eating between 1500-2000 calories per day and sleeping a lot, like 9 hours every night.