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The minimum time you can eat after levothyroxine is 30 minutes...I usually wait an hour. You need to wait 4 hours (not 2) before you can take supplements like calcium and iron (same with multivitamins with calcium and iron).
Memberâ¢7 years on siteâ¢172 posts. It is different for everyone how long the meds take to work. You should be scheduled for a blood test at about 6 - 8 weeks after starting levothyroxine. At that point your dosage may be adjusted, and then another blood test at 6 - 8 weeks. I have realized that being hypothyroid is a test of your patience, it all takes time. My levels stabilized about 9 months after starting medication. Some people take longer than that.