So, when excess pressure is placed on a nerve for a few seconds to several minutes, the nerve loses its ability to conduct its electrical signals. This initially manifests as decreased sensation in the form of a pins and needles, tingling, itching, and/or painful sensation.
Report Abuse. During interphase, the cell is essentially preparing for mitosis. Thus, the nuclear membrane is still intact. The cell is merely replicating its DNA and chromosomes. During mitosis itself, however, the nuclear membrane breaks down so the chromosomes become visible under a microscope.
In this stage the chromosomes become visible and the centrioles separate and move to opposite poles of the cell. Metaphase. The second stage of mitosis. In this stage the chromosomes line up across the center of the cell and become connected to the spindle fiber at their centromere.