Federal Bureau of Prisons. Our Locations. We have many facilities located throughout the nation: 122 institutions, 6 regional offices, a headquarters, 2 staff training centers, and 25 residential reentry management offices. We also administer contracts with private corporations to operate 12 additional correctional institutions. List of our locations.
These are genetic diseases that are due to an abnormal number or structure of the chromosomes. A frequent chromosome anomaly is Down syndrome. These are genetic diseases that are due to a mutation(s) in only 1 gen. They can be inherited in different ways: autosomal dominant, autosomal recessive, X-linked or Y-linked. Frequent monogenic diseases are cystic fibrosis, thalassemia and fragile X syndrome.
Differential Diagnosis of Down Syndrome. Before confirming a diagnosis of Down syndrome, the following conditions are ruled out: 1  Trisomy 18. 2  This condition, which also is called Edward syndrome, is caused by an extra copy of chromosome 18. 3  Babies with Trisomy 18 usually have severe mental retardation and heart problems.