Metastatic bone disease is a serious condition in which cancer has migrated from another part of the body, such as the lung, breast, prostate, thyroid, or kidney into one or more bones of the skeleton. Metastatic bone disease is not the same as cancer that originates in the bone, such as sarcoma.
In this article. Dupuytrenâs contracture, also known as Dupuytrenâs disease, is a hand deformity that causes the tissue beneath the surface of the hand to thicken and contract. Evidence of Dupuytrenâs usually begins with a thickening of the palm.
Symptoms of Dupuytren's Contracture. The first symptom for many patients is one or more lumps (nodules) under the skin in the palm of the hand. The lump may feel tender and sore at first, but this discomfort eventually goes away. The nodules cause tough bands of tissue to form under the skin in the palm.