Air, like other fluids, moves from a region of higher pressure to a region of lower pressure. The flow of air into the lungs. requires that a pressure gradient between the atmosphere and the alveoli be established. This driving pressure. gradient is accomplished by the contraction of the inspiratory muscles.
Rabbit muscle phosphoglucomutase, drawn from PDB: 1JDY â. Phosphoglucomutase (EC 5.4.2.2) is an enzyme that transfers a phosphate group on an Î±-D-glucose monomer from the 1' to the 6' position in the forward direction or the 6' to the 1' position in the reverse direction.More precisely, it facilitates the interconversion of glucose 1-phosphate and glucose 6-phosphate.hosphoglucomutase also acts in the opposite fashion when blood glucose levels are high. In this case, phosphoglucomutase catalyzes the conversion of glucose 6-phosphate (which is easily generated from glucose by the action of hexokinase) to glucose 1-phosphate.
Though it does catalyze the breakdown of glucose, it plays a particularly important role in fructose metabolism, which occurs mostly in the liver, renal cortex, and small intestinal mucosa. When fructose is absorbed, it is phosphorylated by fructokinase to form fructose 1-phosphate.ldolase B then catalyzes F1P breakdown into glyceraldehyde and DHAP. After glyceraldehyde is phosphorylated by triose kinase to form G3P, both products can be used in the glycolytic-gluconeogenic pathway, that is, they can be modified to become either glucose or pyruvate.