Definition of Histiocytosis, Letterer Siwe. Histiocytosis, Letterer Siwe: A severe disease in which histiocytes start to multiply and attack the tissues or organs of the patient starting in infancy with a scaly, sometimes itchy rash on the scalp, ears, abdomen, and creases of the neck and face.
Without the help of Spain, the Netherlands, and especially France, it's unlikely the colonists would have prevailed. Ultimately, the Americans prevailed due to their spirit and the fact that they were fighting for something they believed in. Popular support for the Revolutionary War was overwhelming.
With no other option Burgoyne capitulated on 17 October 1777. The American victory at Saratoga was a major turning point in the war for Independence, heartening the supporters of independence and convincing France to enter in the war as an ally of the fledgling United States.