Which type of reins a rider uses, split reins or one rein, is a matter of personal preference. Split reins are commonly seen in the Western riding disciplines, although some Western riders might use one rein. Split reins are heavily preferred by most working cowboys and cowgirls.
Antimicrotubule agent, mitotic inhibitor Oncology An agent that inhibits cancer growth by stopping cell division Pharmacology A drug that inhibits or blocks mitosis in a particular phase of the cell cycleâeg, metaphase arrest caused by colchicine and vinca alkaloids. See Chemotherapy.
Abstract. Monastrol, a cell-permeable small molecule inhibitor of the mitotic kinesin, Eg5, arrests cells in mitosis with monoastral spindles. Here, we use monastrol to probe mitotic mechanisms. We find that monastrol does not inhibit progression through S and G2 phases of the cell cycle or centrosome duplication.