In fact, degenerative arthritis is thought to involve the entire joint structure with erosion of articular cartilage, hypertrophy of bone at the margins of the affected joint, changes to the synovial membrane (i.e., joint lining), subchondral bone sclerosis, and involvement of the ligaments and periarticular muscles.
14 days: The bullseye rash of lyme disease takes about 14 days to show up. You could have an allergic reaction to a bug bite that will develop within a day. Infection from a bite, not lyme disease, starts getting worse after about 2-3 days.
A shingles rash can mimic spider bites including bed bugs. This rash usually appears on one side of the face or body and lasts from 2 to 4 weeks. Its main symptom is pain, which can be quite severe. Other symptoms of shingles can include fever, headache, chills and upset stomach.