Symptoms of meningitis may include headache, nausea, vomiting, and, in extreme cases, coma. Granulomatous hepatitis and parasitic invasion of the heart, kidney, peritoneum, lymph nodes, pancreas, prostate, ovaries, thyroid, or parathyroid may be present in disseminated disease.
Prev Next. The dark spots that form around acne blemishes result from a condition called postinflammatory hyperpigmentation. Sometimes they're fairly light and unnoticeable, and sometimes they're large dark marks. This condition can also be caused by excessively dry skin.
1 Pregnancy hormones can cause Melasma which make dark patches of skin appear on the face.  Friction: If your thighs rub together, that skin may get darker than the rest of your body. Knees, elbows, underarms and other areas that get rubbed often are typically dark.