Rep: This would be the closest. Open the pdf file in some kind of pdf viewer, print it to files (postscript) having each page as one file, open up the ps file in gimp, mark it up as you want, save the ps files, join the files together with psjoin, use ps2pdf to bring it back to pdf form.
NeulastaÂ® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer Read more medicines (chemotherapy) that can cause fever and low blood cell count.
Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. It serves to stimulate the level of white blood cells (neutrophils). Amgen manufactures pegfilgrastim under the brand name Neulasta, which was mainly worked on by Martine Allard, while Roche manufactures it under the name Neulastim. In India it is also marketed by Abbott Healthcare under the brand name Imupeg. The drug is prepared by coupling a 20 kDa polyethylene glycol (PEG) molecule to the N-terminus of the filgrastim protein. Pegfilgrastim has a human half-life of 15 to 80 hours, much longer than the parent filgrastim (3â4 hours).