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Quadriceps weakness can be caused by various injuries to the knee or hips, acquired myopathies (diseases that affect muscle tissue) such as Lyme disease and poliomyelitis, inherited myopathies such as certain muscular dystrophies and stroke, or neurological diseases such as multiple sclerosis or Bellâs palsy.
The hand will show hyper-extension of the metacarpophalangeal joints (MCP) and flexion at the Interphalangeal (IP) joints of the 2nd and 3rd digits (index and middle). The pathogenesis is similar to that of ulnar clawing (loss of the relevant lumbricals and unopposed action of forearm flexors and extensors).