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Driving distance from Houston, TX to New Orleans, LA. The total driving distance from Houston, TX to New Orleans, LA is 347 miles or 558 kilometers. Your trip begins in Houston, Texas. It ends in New Orleans, Louisiana. If you are planning a road trip, you might also want to calculate the total driving time from Houston, TX to New Orleans, LA so you can see when you'll arrive at your destination.
1. Re: Drive from Houston to New Orleans. Sep 21, 2007, 10:14 AM. It is probably easier to drive between the cities when you factor in the amount of airport check-in and wait time, flight time, car rental time, etc. The drive from DFW airport to Houston is about a 3 1/2 - 4 hour drive and a straight shot down I-45. Same for New Orleans, but a longer drive, straight out I-10.