Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time. Ciprofloxacin may be taken with or without food, but take it at the same time each day. Do not take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified juice.
Melanin granules are seen in the melanocyte, but, astonishingly enough, not so commonly as in the epidermal cells. Melanin granules are composed of numerous fine dense particles (Figs. 3 and 4), which first form small aggregates and finally become the larger, electron-dense melanin granules.
Melanocytes are found in the basal layer of the epidermis as well as in hair follicles, the retina, uveal tract, and leptomeninges. These cells are the sites of origin of melanoma. In areas exposed to the sun, the ratio of melanocytes to keratinocytes is approximately 1:4.