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Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition).Adult-onset Huntington disease, the most common form of this disorder, usually appears in a person's thirties or forties.n rare cases, an individual with Huntington disease does not have a parent with the disorder. As the altered HTT gene is passed from one generation to the next, the size of the CAG trinucleotide repeat often increases in size.
Juvenile Huntington's disease is an uncommon form of the condition that can occur in people younger than 20 years old. Common signs include: 1  a rapid decline in school performance. 2  changes in handwriting.