Federal Bureau of Prisons. Our Locations. We have many facilities located throughout the nation: 122 institutions, 6 regional offices, a headquarters, 2 staff training centers, and 25 residential reentry management offices. We also administer contracts with private corporations to operate 12 additional correctional institutions. List of our locations.
These are genetic diseases that are due to an abnormal number or structure of the chromosomes. A frequent chromosome anomaly is Down syndrome. These are genetic diseases that are due to a mutation(s) in only 1 gen. They can be inherited in different ways: autosomal dominant, autosomal recessive, X-linked or Y-linked. Frequent monogenic diseases are cystic fibrosis, thalassemia and fragile X syndrome.
Monogenic autosomal dominant disorders occur through the inheritance of a single copy of a defective gene. These disorders are the result of a single defective gene on the autosomes.They are inherited according to Mendel's Laws (Mendelian disorders).The mutation can be spontaneous and where there is no previous family history. Inheritance patterns can be autosomal dominant, autosomal recessive or X-linked recessive.hese disorders are the result of a single defective gene on the autosomes. They are inherited according to Mendel's Laws (Mendelian disorders). The mutation can be spontaneous and where there is no previous family history. Inheritance patterns can be autosomal dominant, autosomal recessive or X-linked recessive.