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Quadriceps weakness can be caused by various injuries to the knee or hips, acquired myopathies (diseases that affect muscle tissue) such as Lyme disease and poliomyelitis, inherited myopathies such as certain muscular dystrophies and stroke, or neurological diseases such as multiple sclerosis or Bellâs palsy.
Symptoms of a quadriceps strain or thigh strain typically include a sudden sharp pain at the front of the thigh. Swelling and bruising may develop. A thigh strains are graded 1 to 3 depending on how bad the injury is with a grade 1 being mild and a grade 3 involving a complete or near complete tear of the muscle.