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You can take levothyroxine either one hour before meals or two hours after eating and one hour before taking other meds and any vitamins and supplements but two hours before taking iron or calcium. Source(s): I'm a nurse. Nope, your supposed to take it on an empty stomach, then eat an hour or so after you take it.
Levothyroxine is a synthetic thyroid hormone used to treat hypothyroidism, a condition in which the thyroid gland doesn't produce enough thyroid hormone. The drug is available under the brand names Levothroid, Levoxyl, Levo-T, Synthroid, Tirosint, and Unithroid.: Calcium supplements should be taken 4 hours after levothyroxine due to the fact that calcium will interfere with the absorption of the medication. There does not seem to be any interaction with fiber supplements, but it would be best to wait 4 hours to take these as well.