Prior to the mid-1950s regular dental hygiene didnât hold much promise for oral health. Toothpastes had been formulated since ancient times with ingredients ranging from burnt oyster shells to ground areca nuts. Americans using a soap-and-water-based dentifrice were developing around 700 million cavities a year.
Drug delivery into muscle using an autoinjector, akin to the EpiPen used to treat serious allergic reactions, is faster and may be a more effective way to stop status epilepticus, a prolonged seizure lasting longer than five minutes, according to a study sponsored by the National Institutes of Health.
1 The seizure may begin with an aura or simple partial seizure or they begin with a complex partial that continues and changes into the secondary generalized seizure. 2  The secondary generalized part begins usually with stiffening of the muscles. 3  Air being forced past the vocal cords causes a cry or groan. These seizures generally last 1 to 3 minutes. 2  A tonic-clonic seizure that lasts longer than 5 minutes is a medical emergency. 3  It may be difficult to distinguish these seizures from primary generalized tonic-clonic seizures, especially if they occur during sleep or are not seen by anyone else.