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The most common short-term side effects of radiation therapy for prostate cancer include fatigue, slight reddening of the skin in the treatment area, temporary lowering of blood counts, and urinary and bowel side effects. Brachytherapy and radium 223 dichloride may have some additional or different side effects.
Radiation therapy can be used to: 1  Treat low-grade cancer only in the prostate. 2  Treat cancer that has grown outside of the prostate gland and into nearby tissues. 3  Treat cancer that is not completely removed or returns to the area of the prostate after surgery.  Reduce the size of the tumor if the cancer is advanced.