Congress has authorized FDA to collect an annual establishment registration fee for device establishments. A detailed list of the types of device establishments that are required to register and pay the fee can be found at Who Must Register, List and Pay the Fee. The establishment registration fee is not eligible for a reduced small business fee. The schedule of annual registration user fees for fiscal years 2017 through 2018 follows:
Take note of these common signs of an acute coronary syndrome: 1  Chest pain or discomfort, which may involve pressure, tightness or fullness. 2  Pain or discomfort in one or both arms, the jaw, neck, back or stomach. 3  Shortness of breath.  Feeling dizzy or 1  lightheaded. Nausea.  Sweating.
When a patient presents with chest pain or symptoms suggestive of acute coronary syndrome, vital signs should be obtained, the patient should be monitored, and a focused but careful history should be obtained. A 12-lead ECG should be obtained within 10 minutes of presentation.7.