So, when excess pressure is placed on a nerve for a few seconds to several minutes, the nerve loses its ability to conduct its electrical signals. This initially manifests as decreased sensation in the form of a pins and needles, tingling, itching, and/or painful sensation.
Report Abuse. During interphase, the cell is essentially preparing for mitosis. Thus, the nuclear membrane is still intact. The cell is merely replicating its DNA and chromosomes. During mitosis itself, however, the nuclear membrane breaks down so the chromosomes become visible under a microscope.
For a complete description of the events during Interphase, read about the Cell Cycle. Prophase: During this first mitotic stage, the nucleolus fades and chromatin (replicated DNA and associated proteins) condenses into chromosomes. Each replicated chromosome comprises two chromatids, both with the same genetic information. Microtubules of the cytoskeleton, responsible for cell shape, motility and attachment to other cells during interphase, disassemble.