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You can take levothyroxine either one hour before meals or two hours after eating and one hour before taking other meds and any vitamins and supplements but two hours before taking iron or calcium. Source(s): I'm a nurse. Nope, your supposed to take it on an empty stomach, then eat an hour or so after you take it.
you must take your bills before first meal the best you take it at the same time every morning ,then wait at least 30 to 60 minutes .then if you have another meds you take them after four houre at least to voide any interaction between levothyroxine and them.you will find alot of information in this link do search about levothyroxine .and you will find alot.