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Certain medicines can cause temporary symptoms and signs of lupus. The symptoms go away when you stop taking the medicine, typically within a few weeks. Symptoms are usually milder than in typical lupus, and the kidneys and central nervous system are rarely affected. Some children who take medicines to prevent seizures develop a condition similar to drug-induced lupus seen in adults. Symptoms go away when the child stops taking the medicine. Medicines that may play a role in inducing lupus include: 1  Antibodies to tumor necrosis factor-a. 2  Certain anticonvulsants called hydantoins, such as phenytoin and ethotoin. 3  Chlorpromazine.  D-penicillamine.
Once the symptoms of lupus have responded to treatment, the steroid dose is gradually reduced (tapered). As an alternative to tapering, or stepping down, the steroid dose, your doctor may choose to have you take steroids on an every-other day basis -- one day on, one day off.rednisone is the most commonly prescribed steroid for lupus. Prednisolone and methylprednisolone (MedrolÂ®) are similar to prednisone. Some physicians prefer to prescribe these if you have liver problems. Most people take steroids in pill form, but topical creams or gels are often used for cutaneous (skin) lupus.