Tay-Sachs disease is caused by a defective gene on chromosome 15. When both parents carry the defective Tay-Sachs gene, a child has a 25% chance of developing the disease. The child must receive two copies of the defective gene -- one from each parent -- in order to become sick.
Enacted by law in 2013, the newest symbols of North Carolina are the state art medium, clay; the state fossil, the Megalodon teeth; the state frog, the Pine Barrens tree frog; the state marsupial, the Virginia opossum; and the state salamander, the Marbled salamander.
The adoption of Esse quam videri as the state motto of North Carolina was accompanied by its inclusion in two other important state symbols. It was included at the foot of the coat of arms and engraved in the great seal of North Carolina.