It is used for the prophylaxis or treatment of drug-resistant malaria. It may cause adverse neuropsychiatric reactions and should not be prescribed for prophylaxis in patients with active or recent history of depression, generalized anxiety disorder, psychosis, or schizophrenia or other major psychiatric disorders.
Salem Location. Salem is located in northeast Ohio, in Perry Township, Columbiana County. It is situated about 60 miles southeast of Cleveland, 60 miles northwest of Pittsburgh, 20 miles southwest of Youngstown, and 25 miles east of Canton.
Second only to East Liverpool as Columbiana County's largest city, Salem with its 12,000 population has grown steadily as a city of diversified industries, knowing no boom times and no periods of serious deflation.