Word Origin and History for mesopotamian. ancient name for the land that lies between the Tigris and Euphrates rivers (in modern Iraq), from Greek mesopotamia (khora), literally a country between two rivers, from fem. of mesopotamos, from mesos middle (see medial (adj.)) + potamos river (see potamo-).
Monogenic forms, caused by a single mutation in a dominantly or recessively inherited gene, are well-established, albeit relatively rare types of PD. They collectively account for about 30% of the familial and 3%â5% of the sporadic cases.
The heritability of obesity and body weight in general is high. A small number of confirmed monogenic forms of obesityâthe respective mutations are sufficient by themselves to cause the condition in food abundant societiesâhave been identified by molecular genetic studies.he brain derived neurotrophic factor (BDNF) is involved in weight regulation downstream of the MC4R. Mutations in single genes of the leptinergicâmelanocortinergic pathway have been shown to have a monogenic effect on the development of obesity.