Tay-Sachs disease is caused by a defective gene on chromosome 15. When both parents carry the defective Tay-Sachs gene, a child has a 25% chance of developing the disease. The child must receive two copies of the defective gene -- one from each parent -- in order to become sick.
Enacted by law in 2013, the newest symbols of North Carolina are the state art medium, clay; the state fossil, the Megalodon teeth; the state frog, the Pine Barrens tree frog; the state marsupial, the Virginia opossum; and the state salamander, the Marbled salamander.
The USS Enterprise NCC-1701. NCC was a three-letter prefix first used on Earth starships, then eventually used for ships in service with Starfleet after 2161. (TAS : . The Time Trap ; TOS : . The Cage ) In the mirror universe, NCC was used on ships of the Terran Empire. (TOS :  Mirror, Mirror ) Ships that used the NCC and the NX prefix were listed in the Starfleet Registry.