Rep: This would be the closest. Open the pdf file in some kind of pdf viewer, print it to files (postscript) having each page as one file, open up the ps file in gimp, mark it up as you want, save the ps files, join the files together with psjoin, use ps2pdf to bring it back to pdf form.
NeulastaÂ® is a prescription medication used to help reduce the chance of infection due to a low white blood cell count, in people with certain types of cancer (non-myeloid), who receive anti-cancer Read more medicines (chemotherapy) that can cause fever and low blood cell count.
Upon further investigation, I discovered that Neulasta was among the top 10 best-selling drugs, with nearly $3.6 billion in revenue from July 2013 to July 2014 according to research firm IMS Health. I wondered how a drug given only to cancer patients could generate so much in sales.