Word Origin and History for mesopotamian. ancient name for the land that lies between the Tigris and Euphrates rivers (in modern Iraq), from Greek mesopotamia (khora), literally a country between two rivers, from fem. of mesopotamos, from mesos middle (see medial (adj.)) + potamos river (see potamo-).
Monogenic forms, caused by a single mutation in a dominantly or recessively inherited gene, are well-established, albeit relatively rare types of PD. They collectively account for about 30% of the familial and 3%â5% of the sporadic cases.
Monogenic diseases These are genetic diseases that are due to a mutation(s) in only 1 gen. They can be inherited in different ways: autosomal dominant, autosomal recessive, X-linked or Y-linked. Frequent monogenic diseases are cystic fibrosis, thalassemia and fragile X syndrome.Metabolic diseases These are monogenic that are due to the deficiency of a protein which is important in the metabolism. Examples of metabolic diseases are Phenylketonuria (PKU) and Gaucher disease.Multifactorial diseases These are diseases with a small genetic component.herefore, the mode of inheritance of a monogenic disease is defined by the position of the mutated gene. On the other hand one can also derive the mode of inheritance of the disease by studying the transmission within the family. The geneticist or genetic counseler therefore makes a family pedigree.