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systemic vascular resistance. systemic vascular resistance n. An index of arteriolar constriction throughout the body, calculated by dividing the blood pressure by the cardiac output.
Mean arterial pressure = Cardiac output x Total peripheral resistance. where the total peripheral resistance (TPR) is the sum total of all resistances in the systemic circulation. The factors regulating cardiac output and TPR will be discussed in the subsequent sections 3.2 and 3.3, respectively.