Metastatic bone disease is a serious condition in which cancer has migrated from another part of the body, such as the lung, breast, prostate, thyroid, or kidney into one or more bones of the skeleton. Metastatic bone disease is not the same as cancer that originates in the bone, such as sarcoma.
In this article. Dupuytrenâs contracture, also known as Dupuytrenâs disease, is a hand deformity that causes the tissue beneath the surface of the hand to thicken and contract. Evidence of Dupuytrenâs usually begins with a thickening of the palm.
Dupuytrenâs contracture is an abnormal thickening of the tissue just beneath the skin. This thickening occurs in the palm and can extend into the fingers. Firm pits, bumps and cords (thick lines) can develop and cause the fingers to bend into the palm (Figures 1 and 2).