High doses of vitamin C have been associated with multiple adverse effects. These include blood clotting, death (heart-related), kidney stones, pro-oxidant effects, problems with the digestive system, and red blood cell destruction.
The applications are then scored based upon certain criteria and then winners of the grant are announced. Project grants are a type of categorical grant. Projects are grants given by the federal government to state and local governments on the basis of merit. The other type of categorical grant is a formula grant. These grants, rather than being based on merit, are distributed to all states according to a formula.
Grants were five-year development and demonstration projects. Each consortium developed a plan to begin start-up activities in year one, including initial trials of new learning content and sustained professional development for teachers. Years two and three were devoted to refinement and expansion of the new applications of technology.