Investigating a novel multiplex proteomics technology for detection of changes in serum protein concentrations that may correlate to tumor burden
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'We applied the Quantibody® Human Kiloplex Array to measure 1,000 proteins in sera obtained pre- and post-surgically from 5 pancreatic cancer patients. Sera from two healthy individuals, split into two aliquots each, were used as controls. We found nine proteins which decreased significantly post-surgery and may correlate to tumor burden. To validate the multiplexed results, we used single- target ELISA assays to measure the proteins with the largest serum concentration changes after surgery in sera collected pre- and post-surgically from the previous 5 patients and 10 additional patients. Only 2 of the 8 proteins tested were validated using the ELISA kits' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["proteomics, ELISA, multiplex, immunoassay, pancreatic cancer, protein technologies"]} <|eot_id|>
 Here is the Description of a dataset. Description:'We applied the Quantibody® Human Kiloplex Array to measure 1,000 proteins in sera obtained pre- and post-surgically from 5 pancreatic cancer patients. Sera from two healthy individuals, split into two aliquots each, were used as controls. We found nine proteins which decreased significantly post-surgery and may correlate to tumor burden. To validate the multiplexed results, we used single- target ELISA assays to measure the proteins with the largest serum concentration changes after surgery in sera collected pre- and post-surgically from the previous 5 patients and 10 additional patients. Only 2 of the 8 proteins tested were validated using the ELISA kits' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
We applied the Quantibody® Human Kiloplex Array to measure 1,000 proteins in sera obtained pre- and post-surgically from 5 pancreatic cancer patients. Sera from two healthy individuals, split into two aliquots each, were used as controls. We found nine proteins which decreased significantly post-surgery and may correlate to tumor burden. To validate the multiplexed results, we used single- target ELISA assays to measure the proteins with the largest serum concentration changes after surgery in sera collected pre- and post-surgically from the previous 5 patients and 10 additional patients. Only 2 of the 8 proteins tested were validated using the ELISA kits
proteomics, ELISA, multiplex, immunoassay, pancreatic cancer, protein technologies