Safety and bioactive potential of nanoparticles containing Cantaloupe melon (Cucumis melo L.) carotenoids in obese Wistar rats
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This study evaluated the safety and bioactive potential of nanoparticles containing carotenoids from Cantaloupe melon crude extract and porcine gelatin (EPG) in male obese Wistar rats. Animals were fed with a high glycemic index and high glycemic load (HGLI) diet for 17 days, and treated for ten days with 1) HGLI diet, 2) Standard diet, 3) HGLI diet + EPG (50 mg/Kg) or 4) HGLI diet + crude carotenoid extract (CE) (12.5 mg/Kg). Signs of general toxicity were investigated, considering body weight, food intake, hematological, and biochemical parameters. The relative weight, morphology, and histopathology of the liver, small intestine, kidneys, stomach, and spleen were also evaluated. The biochemical parameters indicated the low toxicity of EPG. Acute hepatitis was observed in the livers of all animals, but those treated with CE and EPG pre' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["β-carotene","Curcubitaceae","Nanotechnology","Toxicity."]} <|eot_id|>
 Here is the Description of a dataset. Description:'This study evaluated the safety and bioactive potential of nanoparticles containing carotenoids from Cantaloupe melon crude extract and porcine gelatin (EPG) in male obese Wistar rats. Animals were fed with a high glycemic index and high glycemic load (HGLI) diet for 17 days, and treated for ten days with 1) HGLI diet, 2) Standard diet, 3) HGLI diet + EPG (50 mg/Kg) or 4) HGLI diet + crude carotenoid extract (CE) (12.5 mg/Kg). Signs of general toxicity were investigated, considering body weight, food intake, hematological, and biochemical parameters. The relative weight, morphology, and histopathology of the liver, small intestine, kidneys, stomach, and spleen were also evaluated. The biochemical parameters indicated the low toxicity of EPG. Acute hepatitis was observed in the livers of all animals, but those treated with CE and EPG pre' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
This study evaluated the safety and bioactive potential of nanoparticles containing carotenoids from Cantaloupe melon crude extract and porcine gelatin (EPG) in male obese Wistar rats. Animals were fed with a high glycemic index and high glycemic load (HGLI) diet for 17 days, and treated for ten days with 1) HGLI diet, 2) Standard diet, 3) HGLI diet + EPG (50 mg/Kg) or 4) HGLI diet + crude carotenoid extract (CE) (12.5 mg/Kg). Signs of general toxicity were investigated, considering body weight, food intake, hematological, and biochemical parameters. The relative weight, morphology, and histopathology of the liver, small intestine, kidneys, stomach, and spleen were also evaluated. The biochemical parameters indicated the low toxicity of EPG. Acute hepatitis was observed in the livers of all animals, but those treated with CE and EPG pre
β-carotene; Curcubitaceae; Nanotechnology; Toxicity.