Sex and tissue differences in estrogen receptor mRNA using ddPCR
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Estrogen is formed by the enzyme aromatase (CYP19A1) and signals via three identified receptors ERα (ESR1), ERß (ESR2), and the G Protein-Coupled Estrogen Receptor (GPER). Understanding, the relative contribution of each receptor to estrogenic signaling may elucidate the disparate effects of this sex hormone across tissues. Moreover, droplet digital PCR is a novel technology that allows absolute quantification and direct comparison of multiple targets. We hypothesized that utilization of this new technology would reveal tissue- and sex-specific differences in estrogen receptor mRNA.' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["ddPCR","estrogen receptors","sex differences"]} <|eot_id|>
 Here is the Description of a dataset. Description:'Estrogen is formed by the enzyme aromatase (CYP19A1) and signals via three identified receptors ERα (ESR1), ERß (ESR2), and the G Protein-Coupled Estrogen Receptor (GPER). Understanding, the relative contribution of each receptor to estrogenic signaling may elucidate the disparate effects of this sex hormone across tissues. Moreover, droplet digital PCR is a novel technology that allows absolute quantification and direct comparison of multiple targets. We hypothesized that utilization of this new technology would reveal tissue- and sex-specific differences in estrogen receptor mRNA.' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
Estrogen is formed by the enzyme aromatase (CYP19A1) and signals via three identified receptors ERα (ESR1), ERß (ESR2), and the G Protein-Coupled Estrogen Receptor (GPER). Understanding, the relative contribution of each receptor to estrogenic signaling may elucidate the disparate effects of this sex hormone across tissues. Moreover, droplet digital PCR is a novel technology that allows absolute quantification and direct comparison of multiple targets. We hypothesized that utilization of this new technology would reveal tissue- and sex-specific differences in estrogen receptor mRNA.
ddPCR; estrogen receptors; sex differences