Contrast-Enhanced Micro-Computed Tomography of Compartment and Time-Dependent Changes in Femoral Cartilage and Subchondral Plate in a Murine Model of Osteoarthritis
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'In this study, we use contrast-enhanced micro-computed tomography (µCT) to establish a timeline of subchondral plate and cartilage changes in the murine femur after destabilization of the medial meniscus (DMM). We performed DMM or sham surgery in 10–12-week-old male C57Bl/6J mice. Femora were imaged using µCT after 0-, 2-, 4-, or 8-weeks. Cartilage-optimized scans were performed after immersion in contrast agent CA4+. Bone mineral density distribution (BMDD), cartilage attenuation, subchondral plate (SCP) and cartilage thickness and volume were measured, including lateral and medial femoral condyle and patellar groove compartments of the operated legs' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["post-traumatic osteoarthritis, cartilage, subchondral plate, contrast-enhanced micro-computed tomography, murine model"]} <|eot_id|>
 Here is the Description of a dataset. Description:'In this study, we use contrast-enhanced micro-computed tomography (µCT) to establish a timeline of subchondral plate and cartilage changes in the murine femur after destabilization of the medial meniscus (DMM). We performed DMM or sham surgery in 10–12-week-old male C57Bl/6J mice. Femora were imaged using µCT after 0-, 2-, 4-, or 8-weeks. Cartilage-optimized scans were performed after immersion in contrast agent CA4+. Bone mineral density distribution (BMDD), cartilage attenuation, subchondral plate (SCP) and cartilage thickness and volume were measured, including lateral and medial femoral condyle and patellar groove compartments of the operated legs' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
In this study, we use contrast-enhanced micro-computed tomography (µCT) to establish a timeline of subchondral plate and cartilage changes in the murine femur after destabilization of the medial meniscus (DMM). We performed DMM or sham surgery in 10–12-week-old male C57Bl/6J mice. Femora were imaged using µCT after 0-, 2-, 4-, or 8-weeks. Cartilage-optimized scans were performed after immersion in contrast agent CA4+. Bone mineral density distribution (BMDD), cartilage attenuation, subchondral plate (SCP) and cartilage thickness and volume were measured, including lateral and medial femoral condyle and patellar groove compartments of the operated legs
post-traumatic osteoarthritis, cartilage, subchondral plate, contrast-enhanced micro-computed tomography, murine model