LncRNA MIR4435-2HG promotes proliferation, migration, invasion and EMT via targeting miR-22-3p/TMEM9B in breast cancer
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Breast cancer, as the malignancy with the highest incidence rate and mortality rate in women, seriously threatens human life and health. Pieces of evidence have suggested that long non-coding RNAs (lncRNAs) possess important effects on regulating the occurrence and development of breast cancer. In addition, microRNA-22-3p (miR-22-3p) expression was down-regulated in breast cancer tissues and cell lines, and negatively associated with lncRNA MIR4435-2HG expression. Over-expression of miR-22-3p obviously inhibited the viability, proliferation, migration, invasion and EMT of breast cancer cell lines. Furthermore, Transmembrane protein 9 domain family member B (TMEM9B) was up-regulated in breast cancer tissues and cell lines and negatively associated with miR-22-3p expression. Finally, TMEM9B inhibition partially restored the effects of lnc' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Breast cancer"]} <|eot_id|>
 Here is the Description of a dataset. Description:'Breast cancer, as the malignancy with the highest incidence rate and mortality rate in women, seriously threatens human life and health. Pieces of evidence have suggested that long non-coding RNAs (lncRNAs) possess important effects on regulating the occurrence and development of breast cancer. In addition, microRNA-22-3p (miR-22-3p) expression was down-regulated in breast cancer tissues and cell lines, and negatively associated with lncRNA MIR4435-2HG expression. Over-expression of miR-22-3p obviously inhibited the viability, proliferation, migration, invasion and EMT of breast cancer cell lines. Furthermore, Transmembrane protein 9 domain family member B (TMEM9B) was up-regulated in breast cancer tissues and cell lines and negatively associated with miR-22-3p expression. Finally, TMEM9B inhibition partially restored the effects of lnc' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
Breast cancer, as the malignancy with the highest incidence rate and mortality rate in women, seriously threatens human life and health. Pieces of evidence have suggested that long non-coding RNAs (lncRNAs) possess important effects on regulating the occurrence and development of breast cancer. In addition, microRNA-22-3p (miR-22-3p) expression was down-regulated in breast cancer tissues and cell lines, and negatively associated with lncRNA MIR4435-2HG expression. Over-expression of miR-22-3p obviously inhibited the viability, proliferation, migration, invasion and EMT of breast cancer cell lines. Furthermore, Transmembrane protein 9 domain family member B (TMEM9B) was up-regulated in breast cancer tissues and cell lines and negatively associated with miR-22-3p expression. Finally, TMEM9B inhibition partially restored the effects of lnc
Breast cancer