Replication Data for: Radical Group Transfer of Vinyl and Alkynyl Silanes Driven by Photoredox Catalysis
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Radical group transfer is a powerful tool for the formation of C–C bonds. These processes typically involve radical addition to C–C π bonds, followed by fragmentation of the cyclic intermediate. Despite the advantageous lability of organosilanes in this context, silicon-tethered radical acceptor groups have remained underexplored in radical group transfer reactions. We report a general photoredox-catalyzed protocol for the radical group transfer of vinyl and alkynyl silanes onto sp3 carbons, using activated and unactivated iodides as radical precursors. Our method displays high diastereoselectivity and excellent functional group tolerance. Mechanistic investigations revealed the key role played by silicon in facilitating a single-electron oxidation step, which leads to direct ring-opening and an overall redox-neutral process.This datase' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["13C NMR","1H NMR","COSY","FTIR","Group transfer","HMBC","HRMS","HSQC","Iodides","Photoredox catalysis","Radical cyclization","Radicals","Ring-opening","Silanes"]} <|eot_id|>
 Here is the Description of a dataset. Description:'Radical group transfer is a powerful tool for the formation of C–C bonds. These processes typically involve radical addition to C–C π bonds, followed by fragmentation of the cyclic intermediate. Despite the advantageous lability of organosilanes in this context, silicon-tethered radical acceptor groups have remained underexplored in radical group transfer reactions. We report a general photoredox-catalyzed protocol for the radical group transfer of vinyl and alkynyl silanes onto sp3 carbons, using activated and unactivated iodides as radical precursors. Our method displays high diastereoselectivity and excellent functional group tolerance. Mechanistic investigations revealed the key role played by silicon in facilitating a single-electron oxidation step, which leads to direct ring-opening and an overall redox-neutral process.This datase' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
Radical group transfer is a powerful tool for the formation of C–C bonds. These processes typically involve radical addition to C–C π bonds, followed by fragmentation of the cyclic intermediate. Despite the advantageous lability of organosilanes in this context, silicon-tethered radical acceptor groups have remained underexplored in radical group transfer reactions. We report a general photoredox-catalyzed protocol for the radical group transfer of vinyl and alkynyl silanes onto sp3 carbons, using activated and unactivated iodides as radical precursors. Our method displays high diastereoselectivity and excellent functional group tolerance. Mechanistic investigations revealed the key role played by silicon in facilitating a single-electron oxidation step, which leads to direct ring-opening and an overall redox-neutral process.This datase
13C NMR; 1H NMR; COSY; FTIR; Group transfer; HMBC; HRMS; HSQC; Iodides; Photoredox catalysis; Radical cyclization; Radicals; Ring-opening; Silanes