Neonatal Brain Concentrations of Buprenorphine and Gabapentin in Prenatally Exposed Mouse Pups
<|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully.  <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The rise in rates of opioid abuse in recent years in the United States has led to a dramatic increase in the incidence of neonatal abstinence syndrome (NAS). Despite improved understanding of NAS and its acute symptoms, there remains a paucity of information regarding the long-term effects of prenatal exposure to drugs of abuse on neurological development. This dataset contains LC-MS/MS-derived drug concentrations of the opioid buprenorphine and the commonly co-abused drug gabapentin from the brains of neonatal mouse pups that were prenatally exposed to the drugs via oral dosing of the pregnant dam. The presence of drug in the brains of these pups was used to validate downstream analysis of excitatory and inhibitory synaptic connectivity in the prenatally-exposed animals.All experiments were conducted in accordance with Marshall Unive' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["LC-MS/MS","opioids","buprenorphine","drugs","brain","neonatal","mice"]} <|eot_id|>
 Here is the Description of a dataset. Description:'The rise in rates of opioid abuse in recent years in the United States has led to a dramatic increase in the incidence of neonatal abstinence syndrome (NAS). Despite improved understanding of NAS and its acute symptoms, there remains a paucity of information regarding the long-term effects of prenatal exposure to drugs of abuse on neurological development. This dataset contains LC-MS/MS-derived drug concentrations of the opioid buprenorphine and the commonly co-abused drug gabapentin from the brains of neonatal mouse pups that were prenatally exposed to the drugs via oral dosing of the pregnant dam. The presence of drug in the brains of these pups was used to validate downstream analysis of excitatory and inhibitory synaptic connectivity in the prenatally-exposed animals.All experiments were conducted in accordance with Marshall Unive' . Please return only a json list of at most 3 Keywords corresponding to the Description:.
The rise in rates of opioid abuse in recent years in the United States has led to a dramatic increase in the incidence of neonatal abstinence syndrome (NAS). Despite improved understanding of NAS and its acute symptoms, there remains a paucity of information regarding the long-term effects of prenatal exposure to drugs of abuse on neurological development. This dataset contains LC-MS/MS-derived drug concentrations of the opioid buprenorphine and the commonly co-abused drug gabapentin from the brains of neonatal mouse pups that were prenatally exposed to the drugs via oral dosing of the pregnant dam. The presence of drug in the brains of these pups was used to validate downstream analysis of excitatory and inhibitory synaptic connectivity in the prenatally-exposed animals.All experiments were conducted in accordance with Marshall Unive
LC-MS/MS; opioids; buprenorphine; drugs; brain; neonatal; mice