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doi:10.11588/data/04HPWW | Cellular correlates of gray matter volume changes in magnetic resonance morphometry identified by two-photon microscopy [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset accompanies the article of the same title in the journal Scientific Reports. It includes a) spreadsheets of data values for each plot in the main figures, b) all raw image data from Two-Photon in vivo microscopy (2pii) c) Custom code d) representative subsets of segmentation label images, coordinates of reidentified nuclei and corresponding magnetic resonance images from all timepoints of one animal (ID S8)' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Correlative Neuroimaging","Microscopy","VBM","Voxel-based Morphometry"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset accompanies the article of the same title in the journal Scientific Reports. It includes a) spreadsheets of data values for each plot in the main figures, b) all raw image data from Two-Photon in vivo microscopy (2pii) c) Custom code d) representative subsets of segmentation label images, coordinates of reidentified nuclei and corresponding magnetic resonance images from all timepoints of one animal (ID S8)' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset accompanies the article of the same title in the journal Scientific Reports. It includes a) spreadsheets of data values for each plot in the main figures, b) all raw image data from Two-Photon in vivo microscopy (2pii) c) Custom code d) representative subsets of segmentation label images, coordinates of reidentified nuclei and corresponding magnetic resonance images from all timepoints of one animal (ID S8) | Medicine, Health and Life Sciences | Correlative Neuroimaging; Microscopy; VBM; Voxel-based Morphometry |
doi:10.11588/data/0Z7H1X | Robust logistic regression to narrow down the winner's curse for rare and recessive susceptibility variants [Source Code] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unusually young age. Robust methods are available to constrain outlier influence, but they are scarcely used in genetic studies. This article provides a non-intimidating introduction to robust logistic regression, and investigates its benefits and limitations in genetic association studies. We applied the bounded Huber and extended the R package ‘robustbase’ with the re-descending Hampel functions to down-weight outlier influence. Computer simulations were carried out to assess the type I error rate, mean squared error (MSE) and statistical power according to major ' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["genetic association study","re-descending Hampel function","robust logistic regression","winner’s curse"]} <|eot_id|> | Here is the Description of a dataset. Description:'Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unusually young age. Robust methods are available to constrain outlier influence, but they are scarcely used in genetic studies. This article provides a non-intimidating introduction to robust logistic regression, and investigates its benefits and limitations in genetic association studies. We applied the bounded Huber and extended the R package ‘robustbase’ with the re-descending Hampel functions to down-weight outlier influence. Computer simulations were carried out to assess the type I error rate, mean squared error (MSE) and statistical power according to major ' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unusually young age. Robust methods are available to constrain outlier influence, but they are scarcely used in genetic studies. This article provides a non-intimidating introduction to robust logistic regression, and investigates its benefits and limitations in genetic association studies. We applied the bounded Huber and extended the R package ‘robustbase’ with the re-descending Hampel functions to down-weight outlier influence. Computer simulations were carried out to assess the type I error rate, mean squared error (MSE) and statistical power according to major | Medicine, Health and Life Sciences | genetic association study; re-descending Hampel function; robust logistic regression; winner’s curse |
doi:10.11588/data/0Z7H1X | Robust logistic regression to narrow down the winner's curse for rare and recessive susceptibility variants [Source Code] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unusually young age. Robust methods are available to constrain outlier influence, but they are scarcely used in genetic studies. This article provides a non-intimidating introduction to robust logistic regression, and investigates its benefits and limitations in genetic association studies. We applied the bounded Huber and extended the R package ‘robustbase’ with the re-descending Hampel functions to down-weight outlier influence. Computer simulations were carried out to assess the type I error rate, mean squared error (MSE) and statistical power according to major ' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["genetic association study","re-descending Hampel function","robust logistic regression","winner’s curse"]} <|eot_id|> | Here is the Description of a dataset. Description:'Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unusually young age. Robust methods are available to constrain outlier influence, but they are scarcely used in genetic studies. This article provides a non-intimidating introduction to robust logistic regression, and investigates its benefits and limitations in genetic association studies. We applied the bounded Huber and extended the R package ‘robustbase’ with the re-descending Hampel functions to down-weight outlier influence. Computer simulations were carried out to assess the type I error rate, mean squared error (MSE) and statistical power according to major ' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Logistic regression is the most common technique used for genetic case-control association studies. A disadvantage of standard maximum likelihood estimators of the genotype relative risk (GRR) is their strong dependence on outlier subjects, for example, patients diagnosed at unusually young age. Robust methods are available to constrain outlier influence, but they are scarcely used in genetic studies. This article provides a non-intimidating introduction to robust logistic regression, and investigates its benefits and limitations in genetic association studies. We applied the bounded Huber and extended the R package ‘robustbase’ with the re-descending Hampel functions to down-weight outlier influence. Computer simulations were carried out to assess the type I error rate, mean squared error (MSE) and statistical power according to major | Medicine, Health and Life Sciences | genetic association study; re-descending Hampel function; robust logistic regression; winner’s curse |
doi:10.11588/data/10028 | Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["BFM","Chromatin","Chromatin folding","Chromatin looping","Cohesin","CTCF","DNA","Dynamic Loop model","Monte-Carlo simulations","Polymer"]} <|eot_id|> | Here is the Description of a dataset. Description:'Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction | Medicine, Health and Life Sciences | BFM; Chromatin; Chromatin folding; Chromatin looping; Cohesin; CTCF; DNA; Dynamic Loop model; Monte-Carlo simulations; Polymer |
doi:10.11588/data/10028 | Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["BFM","Chromatin","Chromatin folding","Chromatin looping","Cohesin","CTCF","DNA","Dynamic Loop model","Monte-Carlo simulations","Polymer"]} <|eot_id|> | Here is the Description of a dataset. Description:'Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Simulations using an advanced version of the Dynamic Loop model were performed to investigate the mechanisms responsible for the experimental finding that the reduction of the chromatin looping proteins CTCF and cohesin leads to chromatin compaction | Physics | BFM; Chromatin; Chromatin folding; Chromatin looping; Cohesin; CTCF; DNA; Dynamic Loop model; Monte-Carlo simulations; Polymer |
doi:10.11588/data/10039 | Factors affecting the uptake of HIV testing among men | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This study aimed to explore factors shaping the decision to undergo Human Immunodeficiency Virus (HIV) testing among men in rural Burkina Faso. The study took place in 2009 in the Nouna Health District and adopted a triangulation mixed methods design. Nouna Health District, is located in north-western Burkina Faso. At the time of the study, the district had a population of approximately 311,000 distributed in 300 villages and included 31 first-line facilities, Centres de Santé et de Promotion Sociale (CSPS)and one district hospital. A sub-portion of the district has been part of a Health and Demographic Surveillance System (HDSS) for over 15 years. Following national policy, starting in 2006, all CSPS were equipped to offer HIV counseling and testing to pregnant women and their partners as the entry point to PMTCT services. Explicit e' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Burkina Faso","HIV testing","men","mixed-methods","sub-Saharan Africa"]} <|eot_id|> | Here is the Description of a dataset. Description:'This study aimed to explore factors shaping the decision to undergo Human Immunodeficiency Virus (HIV) testing among men in rural Burkina Faso. The study took place in 2009 in the Nouna Health District and adopted a triangulation mixed methods design. Nouna Health District, is located in north-western Burkina Faso. At the time of the study, the district had a population of approximately 311,000 distributed in 300 villages and included 31 first-line facilities, Centres de Santé et de Promotion Sociale (CSPS)and one district hospital. A sub-portion of the district has been part of a Health and Demographic Surveillance System (HDSS) for over 15 years. Following national policy, starting in 2006, all CSPS were equipped to offer HIV counseling and testing to pregnant women and their partners as the entry point to PMTCT services. Explicit e' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This study aimed to explore factors shaping the decision to undergo Human Immunodeficiency Virus (HIV) testing among men in rural Burkina Faso. The study took place in 2009 in the Nouna Health District and adopted a triangulation mixed methods design. Nouna Health District, is located in north-western Burkina Faso. At the time of the study, the district had a population of approximately 311,000 distributed in 300 villages and included 31 first-line facilities, Centres de Santé et de Promotion Sociale (CSPS)and one district hospital. A sub-portion of the district has been part of a Health and Demographic Surveillance System (HDSS) for over 15 years. Following national policy, starting in 2006, all CSPS were equipped to offer HIV counseling and testing to pregnant women and their partners as the entry point to PMTCT services. Explicit e | Medicine, Health and Life Sciences | Burkina Faso; HIV testing; men; mixed-methods; sub-Saharan Africa |
doi:10.15139/S3/H3UJMQ | CBEHPP Filter Trial Data | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Long-format household-level data and long-format child-level data for the Community-Based Environmental Health Promotion Programme Filter Trial Study in Rwand' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["WASH","water quality","Rwanda","diarrhea","child health"]} <|eot_id|> | Here is the Description of a dataset. Description:'Long-format household-level data and long-format child-level data for the Community-Based Environmental Health Promotion Programme Filter Trial Study in Rwand' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Long-format household-level data and long-format child-level data for the Community-Based Environmental Health Promotion Programme Filter Trial Study in Rwand | Medicine, Health and Life Sciences | WASH; water quality; Rwanda; diarrhea; child health |
doi:10.15139/S3/H3UJMQ | CBEHPP Filter Trial Data | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Long-format household-level data and long-format child-level data for the Community-Based Environmental Health Promotion Programme Filter Trial Study in Rwand' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["WASH","water quality","Rwanda","diarrhea","child health"]} <|eot_id|> | Here is the Description of a dataset. Description:'Long-format household-level data and long-format child-level data for the Community-Based Environmental Health Promotion Programme Filter Trial Study in Rwand' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Long-format household-level data and long-format child-level data for the Community-Based Environmental Health Promotion Programme Filter Trial Study in Rwand | Social Sciences | WASH; water quality; Rwanda; diarrhea; child health |
doi:10.11588/data/7IWYPF | How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The data and scripts accompany the following manuscript: 'How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations'. To use the data with the R scripts, we recommend downloading them in their original file format (.csv)' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Ambulatory assessment","Ecological momentary assessment","Multilevel modeling","Salivary cortisol","Stress"]} <|eot_id|> | Here is the Description of a dataset. Description:'The data and scripts accompany the following manuscript: 'How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations'. To use the data with the R scripts, we recommend downloading them in their original file format (.csv)' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The data and scripts accompany the following manuscript: 'How to assess and interpret everyday life salivary cortisol measures: A tutorial on practical and statistical considerations'. To use the data with the R scripts, we recommend downloading them in their original file format (.csv) | Medicine, Health and Life Sciences | Ambulatory assessment; Ecological momentary assessment; Multilevel modeling; Salivary cortisol; Stress |
doi:10.11588/data/10092 | HDAMM-predictor: prediction of progression in asymptomatic myeloma patients | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The HDAMM-predictor is based on microarray gene expression and predicts the risk of progression from asymptomatic to symptomatic myeloma. It divides the patients in three groups, from low to high risk to progress. It was generated according to the method published by Rème et al. 2013. Gene expression profiles of 259 asymptomatic myeloma patients were used as trainingset' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Asymptomatic myeloma","Multiple myeloma","Prognosis","Progression","Risk prediction"]} <|eot_id|> | Here is the Description of a dataset. Description:'The HDAMM-predictor is based on microarray gene expression and predicts the risk of progression from asymptomatic to symptomatic myeloma. It divides the patients in three groups, from low to high risk to progress. It was generated according to the method published by Rème et al. 2013. Gene expression profiles of 259 asymptomatic myeloma patients were used as trainingset' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The HDAMM-predictor is based on microarray gene expression and predicts the risk of progression from asymptomatic to symptomatic myeloma. It divides the patients in three groups, from low to high risk to progress. It was generated according to the method published by Rème et al. 2013. Gene expression profiles of 259 asymptomatic myeloma patients were used as trainingset | Medicine, Health and Life Sciences | Asymptomatic myeloma; Multiple myeloma; Prognosis; Progression; Risk prediction |
doi:10.11588/data/10099 | Promoting water consumption using behavioral economics insights [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Mexico has one of the largest overweight and obesity epidemics in the world and as a response, several actions aiming to reduce the obesity epidemic have been already set in place. Some of these actions include a specific action program for schools looking to turn the scholar environments into supportive environments for the infants to make healthier food choices. The influence of the environment (the so-called “choice architecture”) on people’s perceptions and decisions is studied by economists with the aim of supporting individuals’ to make healthier decisions, using tools known as “nudges”. However, 'nudges' are not commonly integrated into anti-obesity strategies. We designed an intervention trying to find out whether such a small, liberty-preserving intervention could increase the effectiveness of a water-promotion campaign, when ' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["behavioral economics","children","nudge","obesity","public health"]} <|eot_id|> | Here is the Description of a dataset. Description:'Mexico has one of the largest overweight and obesity epidemics in the world and as a response, several actions aiming to reduce the obesity epidemic have been already set in place. Some of these actions include a specific action program for schools looking to turn the scholar environments into supportive environments for the infants to make healthier food choices. The influence of the environment (the so-called “choice architecture”) on people’s perceptions and decisions is studied by economists with the aim of supporting individuals’ to make healthier decisions, using tools known as “nudges”. However, 'nudges' are not commonly integrated into anti-obesity strategies. We designed an intervention trying to find out whether such a small, liberty-preserving intervention could increase the effectiveness of a water-promotion campaign, when ' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Mexico has one of the largest overweight and obesity epidemics in the world and as a response, several actions aiming to reduce the obesity epidemic have been already set in place. Some of these actions include a specific action program for schools looking to turn the scholar environments into supportive environments for the infants to make healthier food choices. The influence of the environment (the so-called “choice architecture”) on people’s perceptions and decisions is studied by economists with the aim of supporting individuals’ to make healthier decisions, using tools known as “nudges”. However, 'nudges' are not commonly integrated into anti-obesity strategies. We designed an intervention trying to find out whether such a small, liberty-preserving intervention could increase the effectiveness of a water-promotion campaign, when | Medicine, Health and Life Sciences | behavioral economics; children; nudge; obesity; public health |
doi:10.11588/data/10099 | Promoting water consumption using behavioral economics insights [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Mexico has one of the largest overweight and obesity epidemics in the world and as a response, several actions aiming to reduce the obesity epidemic have been already set in place. Some of these actions include a specific action program for schools looking to turn the scholar environments into supportive environments for the infants to make healthier food choices. The influence of the environment (the so-called “choice architecture”) on people’s perceptions and decisions is studied by economists with the aim of supporting individuals’ to make healthier decisions, using tools known as “nudges”. However, 'nudges' are not commonly integrated into anti-obesity strategies. We designed an intervention trying to find out whether such a small, liberty-preserving intervention could increase the effectiveness of a water-promotion campaign, when ' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["behavioral economics","children","nudge","obesity","public health"]} <|eot_id|> | Here is the Description of a dataset. Description:'Mexico has one of the largest overweight and obesity epidemics in the world and as a response, several actions aiming to reduce the obesity epidemic have been already set in place. Some of these actions include a specific action program for schools looking to turn the scholar environments into supportive environments for the infants to make healthier food choices. The influence of the environment (the so-called “choice architecture”) on people’s perceptions and decisions is studied by economists with the aim of supporting individuals’ to make healthier decisions, using tools known as “nudges”. However, 'nudges' are not commonly integrated into anti-obesity strategies. We designed an intervention trying to find out whether such a small, liberty-preserving intervention could increase the effectiveness of a water-promotion campaign, when ' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Mexico has one of the largest overweight and obesity epidemics in the world and as a response, several actions aiming to reduce the obesity epidemic have been already set in place. Some of these actions include a specific action program for schools looking to turn the scholar environments into supportive environments for the infants to make healthier food choices. The influence of the environment (the so-called “choice architecture”) on people’s perceptions and decisions is studied by economists with the aim of supporting individuals’ to make healthier decisions, using tools known as “nudges”. However, 'nudges' are not commonly integrated into anti-obesity strategies. We designed an intervention trying to find out whether such a small, liberty-preserving intervention could increase the effectiveness of a water-promotion campaign, when | Social Sciences | behavioral economics; children; nudge; obesity; public health |
doi:10.11588/data/3NKHAY | Dual kinetic and structural role for the surface in guiding SAS-6 self-assembly to direct centriole architecture [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication:Discovering mechanisms governing organelle assembly is a fundamental pursuit in the life sciences. The centriole is an evolutionarily conserved organelle with a signature 9-fold symmetrical chiral arrangement of microtubules imparted onto the cilium it templates. The first structure in nascent centrioles is a cartwheel, which comprises stacked 9-fold symmetrical SAS-6 ring polymers and emerging orthogonal to a surface surrounding resident centrioles. The mechanisms through which SAS-6 polymerization ensures centriole organelle architecture remain elusive. We deployed photothermally-actuated off-resonance tapping high-' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["centriole assembly","coarse-graining","Martini force field","MD simulation","SAS-6"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication:Discovering mechanisms governing organelle assembly is a fundamental pursuit in the life sciences. The centriole is an evolutionarily conserved organelle with a signature 9-fold symmetrical chiral arrangement of microtubules imparted onto the cilium it templates. The first structure in nascent centrioles is a cartwheel, which comprises stacked 9-fold symmetrical SAS-6 ring polymers and emerging orthogonal to a surface surrounding resident centrioles. The mechanisms through which SAS-6 polymerization ensures centriole organelle architecture remain elusive. We deployed photothermally-actuated off-resonance tapping high-' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains input structures and parameters for coarse-grained molecular dynamics simulation of SAS-6 protein oligomers as well as post-processing files and analysis scripts. Abstract of related publication:Discovering mechanisms governing organelle assembly is a fundamental pursuit in the life sciences. The centriole is an evolutionarily conserved organelle with a signature 9-fold symmetrical chiral arrangement of microtubules imparted onto the cilium it templates. The first structure in nascent centrioles is a cartwheel, which comprises stacked 9-fold symmetrical SAS-6 ring polymers and emerging orthogonal to a surface surrounding resident centrioles. The mechanisms through which SAS-6 polymerization ensures centriole organelle architecture remain elusive. We deployed photothermally-actuated off-resonance tapping high- | Medicine, Health and Life Sciences | centriole assembly; coarse-graining; Martini force field; MD simulation; SAS-6 |
doi:10.11588/data/5JCEVW | Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This is the research data from the publication 'Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey.' The research data includes the questionnaire, the data set used, and a description of the data preparation' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["clinical data","data access","data sharing","health data","physician attitudes","physician-scientists","secondary use"]} <|eot_id|> | Here is the Description of a dataset. Description:'This is the research data from the publication 'Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey.' The research data includes the questionnaire, the data set used, and a description of the data preparation' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This is the research data from the publication 'Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey.' The research data includes the questionnaire, the data set used, and a description of the data preparation | Medicine, Health and Life Sciences | clinical data; data access; data sharing; health data; physician attitudes; physician-scientists; secondary use |
doi:10.11588/data/5JCEVW | Physicians’ Attitudes towards Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey. [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This is the research data from the publication 'Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey.' The research data includes the questionnaire, the data set used, and a description of the data preparation' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["clinical data","data access","data sharing","health data","physician attitudes","physician-scientists","secondary use"]} <|eot_id|> | Here is the Description of a dataset. Description:'This is the research data from the publication 'Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey.' The research data includes the questionnaire, the data set used, and a description of the data preparation' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This is the research data from the publication 'Physicians' Attitudes toward Secondary Use of Clinical Data for Biomedical Research Purposes. Results of a Quantitative Survey.' The research data includes the questionnaire, the data set used, and a description of the data preparation | Social Sciences | clinical data; data access; data sharing; health data; physician attitudes; physician-scientists; secondary use |
doi:10.11588/data/5RSAM3 | DCE-MRI of the human kidney using BLADE: A feasibility study in healthy volunteers [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'To evaluate the degree of motion compensation in the kidney using two different sampling methods, each in their optimized settings: A BLADE k-space acquisition technique and a routinely used kidney perfusion acquisition scheme (TurboFLASH).Dynamic contrast enhanced magnetic resonance examinations were performed in 16 healthy volunteers on a 3 Tesla MR-system with two parameterizations of the BLADE sequence and the standard reference acquisition scheme. Signal intensity enhanced time curves were analyzed with a mathematical model and a widely published separable compartment model on cortex regions to assess robustness versus motion artifact' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["BLADE","DCE-MRI","Motion Correction","Perfusion"]} <|eot_id|> | Here is the Description of a dataset. Description:'To evaluate the degree of motion compensation in the kidney using two different sampling methods, each in their optimized settings: A BLADE k-space acquisition technique and a routinely used kidney perfusion acquisition scheme (TurboFLASH).Dynamic contrast enhanced magnetic resonance examinations were performed in 16 healthy volunteers on a 3 Tesla MR-system with two parameterizations of the BLADE sequence and the standard reference acquisition scheme. Signal intensity enhanced time curves were analyzed with a mathematical model and a widely published separable compartment model on cortex regions to assess robustness versus motion artifact' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | To evaluate the degree of motion compensation in the kidney using two different sampling methods, each in their optimized settings: A BLADE k-space acquisition technique and a routinely used kidney perfusion acquisition scheme (TurboFLASH).Dynamic contrast enhanced magnetic resonance examinations were performed in 16 healthy volunteers on a 3 Tesla MR-system with two parameterizations of the BLADE sequence and the standard reference acquisition scheme. Signal intensity enhanced time curves were analyzed with a mathematical model and a widely published separable compartment model on cortex regions to assess robustness versus motion artifact | Medicine, Health and Life Sciences | BLADE; DCE-MRI; Motion Correction; Perfusion |
doi:10.11588/data/7NRFYC | Synthesis of CT images from digital body phantoms using CycleGAN [dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["CT synthesis","CycleGAN","Generative Adversial Networks","physical modeling","simulation based deep learning"]} <|eot_id|> | Here is the Description of a dataset. Description:'The potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms | Computer and Information Science | CT synthesis; CycleGAN; Generative Adversial Networks; physical modeling; simulation based deep learning |
doi:10.11588/data/7NRFYC | Synthesis of CT images from digital body phantoms using CycleGAN [dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["CT synthesis","CycleGAN","Generative Adversial Networks","physical modeling","simulation based deep learning"]} <|eot_id|> | Here is the Description of a dataset. Description:'The potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The potential of medical image analysis with neural networks is limited by the restricted availability of extensive data sets. The incorporation of synthetic training data is one approach to bypass this shortcoming, as synthetic data offer accurate annotations and unlimited data size. We evaluated eleven CycleGAN for the synthesis of computed tomography (CT) images based on XCAT body phantoms | Medicine, Health and Life Sciences | CT synthesis; CycleGAN; Generative Adversial Networks; physical modeling; simulation based deep learning |
doi:10.11588/data/8LKEZF | Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University. The HE-Staining Variation (HEV) data set offers serial sections of a follicular thyroid carcinoma, stained with different HE-staining protocols (including name of [stainVariant]):stained with HE with the standard protocol of the Institute of Pathology, Mannheim (HE)stained too long with HE (longHE)stained too short with HE (shortHE)stained only with Hematoxylin (onlyH)stained only with Eosin (onlyE)stained too long with Hematoxylin (' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Stain Normalization"]} <|eot_id|> | Here is the Description of a dataset. Description:'Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University. The HE-Staining Variation (HEV) data set offers serial sections of a follicular thyroid carcinoma, stained with different HE-staining protocols (including name of [stainVariant]):stained with HE with the standard protocol of the Institute of Pathology, Mannheim (HE)stained too long with HE (longHE)stained too short with HE (shortHE)stained only with Hematoxylin (onlyH)stained only with Eosin (onlyE)stained too long with Hematoxylin (' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University. The HE-Staining Variation (HEV) data set offers serial sections of a follicular thyroid carcinoma, stained with different HE-staining protocols (including name of [stainVariant]):stained with HE with the standard protocol of the Institute of Pathology, Mannheim (HE)stained too long with HE (longHE)stained too short with HE (shortHE)stained only with Hematoxylin (onlyH)stained only with Eosin (onlyE)stained too long with Hematoxylin ( | Computer and Information Science | Stain Normalization |
doi:10.11588/data/8LKEZF | Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University. The HE-Staining Variation (HEV) data set offers serial sections of a follicular thyroid carcinoma, stained with different HE-staining protocols (including name of [stainVariant]):stained with HE with the standard protocol of the Institute of Pathology, Mannheim (HE)stained too long with HE (longHE)stained too short with HE (shortHE)stained only with Hematoxylin (onlyH)stained only with Eosin (onlyE)stained too long with Hematoxylin (' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Stain Normalization"]} <|eot_id|> | Here is the Description of a dataset. Description:'Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University. The HE-Staining Variation (HEV) data set offers serial sections of a follicular thyroid carcinoma, stained with different HE-staining protocols (including name of [stainVariant]):stained with HE with the standard protocol of the Institute of Pathology, Mannheim (HE)stained too long with HE (longHE)stained too short with HE (shortHE)stained only with Hematoxylin (onlyH)stained only with Eosin (onlyE)stained too long with Hematoxylin (' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Here we provide the data sets supporting the experiments in our publication Normalization of HE-Stained Histological Images using Cycle Consistent Generative Adversarial Networks, which were collected at the Institute of Pathology, Medical Faculty Mannheim, Heidelberg University. The HE-Staining Variation (HEV) data set offers serial sections of a follicular thyroid carcinoma, stained with different HE-staining protocols (including name of [stainVariant]):stained with HE with the standard protocol of the Institute of Pathology, Mannheim (HE)stained too long with HE (longHE)stained too short with HE (shortHE)stained only with Hematoxylin (onlyH)stained only with Eosin (onlyE)stained too long with Hematoxylin ( | Medicine, Health and Life Sciences | Stain Normalization |
doi:10.11588/data/AOSUS8 | Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development - in vivo imaging of OV formation | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Development of a functional retina is accompanied by several morphological events transitions that ultimately result in the formation of a functional retina. One of them is the formation of the OV. When fish-derived organoids were generated with reduced cell-seeding density by 50%, the organoids formed individual domains reminiscent of the forming optic vesicle in vivo. To address the mode of OV formation in fish organoids, we employed live imaging of Rx3::H2B-GFP-derived organoids from day 1 to day 2 of development. This dataset is a raw data from live imaging of Rx3::H2B-GFP-derived organoids from day 1 to day 2 of development performed on the 16× detection MuVi SPIM Multiview light-sheet microscope (Luxendo Light-sheet, Bruker Corporation)' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["in vivo imaging","light-sheet microscopy","medaka fish","organoid","retina"]} <|eot_id|> | Here is the Description of a dataset. Description:'Development of a functional retina is accompanied by several morphological events transitions that ultimately result in the formation of a functional retina. One of them is the formation of the OV. When fish-derived organoids were generated with reduced cell-seeding density by 50%, the organoids formed individual domains reminiscent of the forming optic vesicle in vivo. To address the mode of OV formation in fish organoids, we employed live imaging of Rx3::H2B-GFP-derived organoids from day 1 to day 2 of development. This dataset is a raw data from live imaging of Rx3::H2B-GFP-derived organoids from day 1 to day 2 of development performed on the 16× detection MuVi SPIM Multiview light-sheet microscope (Luxendo Light-sheet, Bruker Corporation)' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Development of a functional retina is accompanied by several morphological events transitions that ultimately result in the formation of a functional retina. One of them is the formation of the OV. When fish-derived organoids were generated with reduced cell-seeding density by 50%, the organoids formed individual domains reminiscent of the forming optic vesicle in vivo. To address the mode of OV formation in fish organoids, we employed live imaging of Rx3::H2B-GFP-derived organoids from day 1 to day 2 of development. This dataset is a raw data from live imaging of Rx3::H2B-GFP-derived organoids from day 1 to day 2 of development performed on the 16× detection MuVi SPIM Multiview light-sheet microscope (Luxendo Light-sheet, Bruker Corporation) | Medicine, Health and Life Sciences | in vivo imaging; light-sheet microscopy; medaka fish; organoid; retina |
doi:10.11588/data/ARWJHB | Mittelalterliche Pflanzenreste von der Marktstätte und Brotlaube in Konstanz [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Archaeobotany","Konstanz","Middle Ages"]} <|eot_id|> | Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded | Arts and Humanities | Archaeobotany; Konstanz; Middle Ages |
doi:10.11588/data/ARWJHB | Mittelalterliche Pflanzenreste von der Marktstätte und Brotlaube in Konstanz [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Archaeobotany","Konstanz","Middle Ages"]} <|eot_id|> | Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded | Medicine, Health and Life Sciences | Archaeobotany; Konstanz; Middle Ages |
doi:10.11588/data/ARWJHB | Mittelalterliche Pflanzenreste von der Marktstätte und Brotlaube in Konstanz [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Archaeobotany","Konstanz","Middle Ages"]} <|eot_id|> | Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded | Arts and Humanities | Archaeobotany; Konstanz; Middle Ages |
doi:10.11588/data/ARWJHB | Mittelalterliche Pflanzenreste von der Marktstätte und Brotlaube in Konstanz [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Archaeobotany","Konstanz","Middle Ages"]} <|eot_id|> | Here is the Description of a dataset. Description:'During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | During excavations in medieval Konstanz very many samples were taken for archaeobotanical analyses. Samples could be dated to different time layers from High to Late Middle Ages. Spelt, millet and oats were probably the most important cereals. But also flax, hemp, figs and spices were recorded | Medicine, Health and Life Sciences | Archaeobotany; Konstanz; Middle Ages |
doi:10.11588/data/BQTQUN | Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site [research data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-terminal FERM domain binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-enriched membranes. A newly published autoinhibitory structure of talin-1, where the known PIP2 interaction sites are covered up, lead us to hypothesize that a hitherto less examined loop insertion of the FERM domain acts as an additional and initial site of contact. We evaluated direct interactions of talin-1 with a PIP2 membrane by means of atomistic molecular dynamics (MD) simulations. We show that this unstructured, 33-residue-long loop strongly interact' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["molecular dynamics","PIP2","talin-1"]} <|eot_id|> | Here is the Description of a dataset. Description:'Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-terminal FERM domain binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-enriched membranes. A newly published autoinhibitory structure of talin-1, where the known PIP2 interaction sites are covered up, lead us to hypothesize that a hitherto less examined loop insertion of the FERM domain acts as an additional and initial site of contact. We evaluated direct interactions of talin-1 with a PIP2 membrane by means of atomistic molecular dynamics (MD) simulations. We show that this unstructured, 33-residue-long loop strongly interact' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Focal adhesions (FAs) mediate the interaction of the cytoskeleton with the extracellular matrix (ECM) in a highly dynamic fashion. talin is a central regulator, adaptor protein and mechano-sensor of focal adhesion complexes. For recruitment and firm attachment at FAs, talin’s N-terminal FERM domain binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-enriched membranes. A newly published autoinhibitory structure of talin-1, where the known PIP2 interaction sites are covered up, lead us to hypothesize that a hitherto less examined loop insertion of the FERM domain acts as an additional and initial site of contact. We evaluated direct interactions of talin-1 with a PIP2 membrane by means of atomistic molecular dynamics (MD) simulations. We show that this unstructured, 33-residue-long loop strongly interact | Medicine, Health and Life Sciences | molecular dynamics; PIP2; talin-1 |
doi:10.11588/data/D0ACC0 | Evaluation of the accuracy, exclusivity, limit-of-detection and ease-of-use of the LumiraDx SARS-CoV-2 test - A rapid, antigen-detecting point-of-care tool for the diagnosis of SARS-CoV-2 [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to viral load, days of symptoms and symptoms. In addition, further data from the participants were collected during interview' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["antigen-detecting rapid tests","Covid-19","Diagnostics","SARS-CoV-2"]} <|eot_id|> | Here is the Description of a dataset. Description:'This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to viral load, days of symptoms and symptoms. In addition, further data from the participants were collected during interview' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to viral load, days of symptoms and symptoms. In addition, further data from the participants were collected during interview | Medicine, Health and Life Sciences | antigen-detecting rapid tests; Covid-19; Diagnostics; SARS-CoV-2 |
doi:10.11588/data/DNOSZG | Monosynaptic trans-collicular pathways for sensory-motor integration in the whisker system [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains electrophysiological spike time data and figure data for anatomical quantifications reported in Martín-Cortecero et al. Monosynaptic trans-collicular pathways for sensory-motor integration in the whisker system(2023).Abstract: The superior colliculus (SC), a conserved midbrain-node with extensive long-range connectivity throughout the brain, is a key structure for innate behaviors. Descending cortical pathways are increasingly recognized as central control points for SC-mediated behaviors, but how cortico-collicular pathways coordinate SC activity at the cellular level is poorly understood. Moreover, despite the known role of the SC as a multisensory integrator, the involvement of the SC in the somatosensory system is largely unexplored in comparison to its involvement in the visual and auditory systems. Here, w' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["optogenetics","sensory circuits","sensory-motor convergence","spike time data","superior colliculus","whisker system"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains electrophysiological spike time data and figure data for anatomical quantifications reported in Martín-Cortecero et al. Monosynaptic trans-collicular pathways for sensory-motor integration in the whisker system(2023).Abstract: The superior colliculus (SC), a conserved midbrain-node with extensive long-range connectivity throughout the brain, is a key structure for innate behaviors. Descending cortical pathways are increasingly recognized as central control points for SC-mediated behaviors, but how cortico-collicular pathways coordinate SC activity at the cellular level is poorly understood. Moreover, despite the known role of the SC as a multisensory integrator, the involvement of the SC in the somatosensory system is largely unexplored in comparison to its involvement in the visual and auditory systems. Here, w' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains electrophysiological spike time data and figure data for anatomical quantifications reported in Martín-Cortecero et al. Monosynaptic trans-collicular pathways for sensory-motor integration in the whisker system(2023).Abstract: The superior colliculus (SC), a conserved midbrain-node with extensive long-range connectivity throughout the brain, is a key structure for innate behaviors. Descending cortical pathways are increasingly recognized as central control points for SC-mediated behaviors, but how cortico-collicular pathways coordinate SC activity at the cellular level is poorly understood. Moreover, despite the known role of the SC as a multisensory integrator, the involvement of the SC in the somatosensory system is largely unexplored in comparison to its involvement in the visual and auditory systems. Here, w | Medicine, Health and Life Sciences | optogenetics; sensory circuits; sensory-motor convergence; spike time data; superior colliculus; whisker system |
doi:10.11588/data/EIXOPN | Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis from SIRS on ICU Admission | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Background: Infection can induce granulopoiesis. This process potentially gives rise to blood gene classifiers of sepsis in systemic inflammatory response syndrome (SIRS) patients. The aim of this study was to identify sepsis signature genes in blood granulocytes from patients with sepsis and SIRS on intensive care unit (ICU) admission.Methods: CD15+ cells encompassing all stage of terminal granulocytic differentiation were analyzed. CD15 transcriptomes from patients with sepsis and SIRS on ICU admission and presurgical controls (discovery cohort) were subjected to differential gene expression and pathway enrichment analyses. Differential expression was validated by bead array in independent sepsis and SIRS patients (validation cohort). We referred to the GeneCards database for subcellular gene associations and Grassi et al. (Cell Rep ' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["granulocytes","intensive care unit","sepsis","signature genes","systemic inflammatory response syndrome"]} <|eot_id|> | Here is the Description of a dataset. Description:'Background: Infection can induce granulopoiesis. This process potentially gives rise to blood gene classifiers of sepsis in systemic inflammatory response syndrome (SIRS) patients. The aim of this study was to identify sepsis signature genes in blood granulocytes from patients with sepsis and SIRS on intensive care unit (ICU) admission.Methods: CD15+ cells encompassing all stage of terminal granulocytic differentiation were analyzed. CD15 transcriptomes from patients with sepsis and SIRS on ICU admission and presurgical controls (discovery cohort) were subjected to differential gene expression and pathway enrichment analyses. Differential expression was validated by bead array in independent sepsis and SIRS patients (validation cohort). We referred to the GeneCards database for subcellular gene associations and Grassi et al. (Cell Rep ' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Background: Infection can induce granulopoiesis. This process potentially gives rise to blood gene classifiers of sepsis in systemic inflammatory response syndrome (SIRS) patients. The aim of this study was to identify sepsis signature genes in blood granulocytes from patients with sepsis and SIRS on intensive care unit (ICU) admission.Methods: CD15+ cells encompassing all stage of terminal granulocytic differentiation were analyzed. CD15 transcriptomes from patients with sepsis and SIRS on ICU admission and presurgical controls (discovery cohort) were subjected to differential gene expression and pathway enrichment analyses. Differential expression was validated by bead array in independent sepsis and SIRS patients (validation cohort). We referred to the GeneCards database for subcellular gene associations and Grassi et al. (Cell Rep | Medicine, Health and Life Sciences | granulocytes; intensive care unit; sepsis; signature genes; systemic inflammatory response syndrome |
doi:10.11588/data/FHOCRZ | Raw data and analysis scripts for 'Design and application of an MR reference phantom for multicentre lung imaging trials' | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized.AbstractIntroduction:As there is an increasing number of multicentre lung imaging studies with MRI in patients, dedicated reference phantoms are required to allow for the assessment and comparison of image quality in multi-vendor and multi-centre environments. However, appropriate phantoms for this purpose are so far not available commercially. It was therefore the purpose of this project to design and evaluate a cost-effective and simple to use reference phantom which addresses the specific requirements for imaging the lungs with MRI.Methods:We designed and em' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["lung imaging","MR phantoms","multicentre trials"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized.AbstractIntroduction:As there is an increasing number of multicentre lung imaging studies with MRI in patients, dedicated reference phantoms are required to allow for the assessment and comparison of image quality in multi-vendor and multi-centre environments. However, appropriate phantoms for this purpose are so far not available commercially. It was therefore the purpose of this project to design and evaluate a cost-effective and simple to use reference phantom which addresses the specific requirements for imaging the lungs with MRI.Methods:We designed and em' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized.AbstractIntroduction:As there is an increasing number of multicentre lung imaging studies with MRI in patients, dedicated reference phantoms are required to allow for the assessment and comparison of image quality in multi-vendor and multi-centre environments. However, appropriate phantoms for this purpose are so far not available commercially. It was therefore the purpose of this project to design and evaluate a cost-effective and simple to use reference phantom which addresses the specific requirements for imaging the lungs with MRI.Methods:We designed and em | Medicine, Health and Life Sciences | lung imaging; MR phantoms; multicentre trials |
doi:10.11588/data/FHOCRZ | Raw data and analysis scripts for 'Design and application of an MR reference phantom for multicentre lung imaging trials' | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized.AbstractIntroduction:As there is an increasing number of multicentre lung imaging studies with MRI in patients, dedicated reference phantoms are required to allow for the assessment and comparison of image quality in multi-vendor and multi-centre environments. However, appropriate phantoms for this purpose are so far not available commercially. It was therefore the purpose of this project to design and evaluate a cost-effective and simple to use reference phantom which addresses the specific requirements for imaging the lungs with MRI.Methods:We designed and em' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["lung imaging","MR phantoms","multicentre trials"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized.AbstractIntroduction:As there is an increasing number of multicentre lung imaging studies with MRI in patients, dedicated reference phantoms are required to allow for the assessment and comparison of image quality in multi-vendor and multi-centre environments. However, appropriate phantoms for this purpose are so far not available commercially. It was therefore the purpose of this project to design and evaluate a cost-effective and simple to use reference phantom which addresses the specific requirements for imaging the lungs with MRI.Methods:We designed and em' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains all MRI phantom data discussed in the related publication as well as the python scripts used to analyse them. The format is DICOM files, where institution names and adresses have been anonymized.AbstractIntroduction:As there is an increasing number of multicentre lung imaging studies with MRI in patients, dedicated reference phantoms are required to allow for the assessment and comparison of image quality in multi-vendor and multi-centre environments. However, appropriate phantoms for this purpose are so far not available commercially. It was therefore the purpose of this project to design and evaluate a cost-effective and simple to use reference phantom which addresses the specific requirements for imaging the lungs with MRI.Methods:We designed and em | Medicine, Health and Life Sciences | lung imaging; MR phantoms; multicentre trials |
doi:10.11588/data/FSPQL4 | The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2 - Evaluation of the accuracy and ease-of-use [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to cycle-threshold values, days of symptoms, disease severity and study site. In addition, further data from the participants were collected during interviews' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Antigen-detecting","Covid-19","Diagnostics","SARS-CoV-2"]} <|eot_id|> | Here is the Description of a dataset. Description:'This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to cycle-threshold values, days of symptoms, disease severity and study site. In addition, further data from the participants were collected during interviews' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This repository includes data from a prospective, multi-centre diagnostic accuracy study. The study was conducted at two sites in Germany, Heidelberg and Berlin. Following routine testing with reverse-transcriptase polymerase chain reaction (RT-PCR), a second study-exclusive swab was performed for Ag-RDT testing. Routine swabs were nasopharyngeal (NP) or combined NP/oropharyngeal (OP) whereas the study-exclusive swabs were NP. To evaluate performance, sensitivity and specificity were assessed overall and in predefined sub analyses accordingly to cycle-threshold values, days of symptoms, disease severity and study site. In addition, further data from the participants were collected during interviews | Medicine, Health and Life Sciences | Antigen-detecting; Covid-19; Diagnostics; SARS-CoV-2 |
doi:10.11588/data/GEEBLZ | Social and Cognitive Congruence [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains the R-Script of our Evaluation and the dataset on which our results are based' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Peer-Assisted Learning","Social and Cognitive Congruence"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains the R-Script of our Evaluation and the dataset on which our results are based' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains the R-Script of our Evaluation and the dataset on which our results are based | Medicine, Health and Life Sciences | Peer-Assisted Learning; Social and Cognitive Congruence |
doi:10.11588/data/HJ6SVM | Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Collagen","KIMMDY","Mechanoracials","Molecular Dynamics"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in | Chemistry | Collagen; KIMMDY; Mechanoracials; Molecular Dynamics |
doi:10.11588/data/HJ6SVM | Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Collagen","KIMMDY","Mechanoracials","Molecular Dynamics"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in | Computer and Information Science | Collagen; KIMMDY; Mechanoracials; Molecular Dynamics |
doi:10.11588/data/HJ6SVM | Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Collagen","KIMMDY","Mechanoracials","Molecular Dynamics"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in | Medicine, Health and Life Sciences | Collagen; KIMMDY; Mechanoracials; Molecular Dynamics |
doi:10.11588/data/HJ6SVM | Collagen breaks at weak sacrificial bonds taming its mechanoradicals [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Collagen","KIMMDY","Mechanoracials","Molecular Dynamics"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains input files for MD simulations, derived breakage counts from these simulations that are used to generate the figures in the publication, and the experimental, uncropped SDS-PAGE gels of the presented results in the related publication. Abstract of related publication: Collagen is a force-bearing, hierarchical structural protein important to all connective tissue. In tendon collagen, high load even below macroscopic failure level creates mechanoradicals by homolytic bond scission, similar to polymers. The location and type of initial rupture sites critically decide on both the mechanical and chemical impact of these micro-ruptures on the tissue, but are yet to be explored. Wehere use scale-bridging simulations supported by gel electrophoresis and mass spectrometry to determine breakage points in | Physics | Collagen; KIMMDY; Mechanoracials; Molecular Dynamics |
doi:10.11588/data/ICSFUS | Multimodal ground truth datasets for abdominal medical image registration [data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Sparsity of annotated data is a major limitation in medical image processing tasks such as registration. Registered multimodal image data are essential for the diagnosis of medical conditions and the success of interventional medical procedures. To overcome the shortage of data, we present a method that allows the generation of annotated multimodal 4D datasets.We use a CycleGAN network architecture to generate multimodal synthetic data from the 4D extended cardiac–torso (XCAT) phantom and real patient data. Organ masks are provided by the XCAT phantom; therefore, the generated dataset can serve as ground truth for image segmentation and registration. Compared to real patient data, the synthetic data showed good agreement regarding the image voxel intensity distribution and the noise characteristics. The generated T1-weighted magnetic ' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["CycleGAN","image registration","image synthesis","liver","multimodal imaging"]} <|eot_id|> | Here is the Description of a dataset. Description:'Sparsity of annotated data is a major limitation in medical image processing tasks such as registration. Registered multimodal image data are essential for the diagnosis of medical conditions and the success of interventional medical procedures. To overcome the shortage of data, we present a method that allows the generation of annotated multimodal 4D datasets.We use a CycleGAN network architecture to generate multimodal synthetic data from the 4D extended cardiac–torso (XCAT) phantom and real patient data. Organ masks are provided by the XCAT phantom; therefore, the generated dataset can serve as ground truth for image segmentation and registration. Compared to real patient data, the synthetic data showed good agreement regarding the image voxel intensity distribution and the noise characteristics. The generated T1-weighted magnetic ' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Sparsity of annotated data is a major limitation in medical image processing tasks such as registration. Registered multimodal image data are essential for the diagnosis of medical conditions and the success of interventional medical procedures. To overcome the shortage of data, we present a method that allows the generation of annotated multimodal 4D datasets.We use a CycleGAN network architecture to generate multimodal synthetic data from the 4D extended cardiac–torso (XCAT) phantom and real patient data. Organ masks are provided by the XCAT phantom; therefore, the generated dataset can serve as ground truth for image segmentation and registration. Compared to real patient data, the synthetic data showed good agreement regarding the image voxel intensity distribution and the noise characteristics. The generated T1-weighted magnetic | Medicine, Health and Life Sciences | CycleGAN; image registration; image synthesis; liver; multimodal imaging |
doi:10.11588/data/JM2H6I | A framework for assessing import costs of medical supplies and results for a tuberculosis program in Karakalpakstan, Uzbekistan [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Data and cod' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Central Asia","Cost Analysis","Freight Costs","Health program","Humanitarian Aid","Import Costs","Shipping Costs","Supply Chain","Transportation Costs","Tuberculosis","Uzbekistan"]} <|eot_id|> | Here is the Description of a dataset. Description:'Data and cod' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Data and cod | Medicine, Health and Life Sciences | Central Asia; Cost Analysis; Freight Costs; Health program; Humanitarian Aid; Import Costs; Shipping Costs; Supply Chain; Transportation Costs; Tuberculosis; Uzbekistan |
doi:10.11588/data/JWLFFZ | Activity of AcD and nonAcD cells during high-frequency network oscillations [data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Information processing in neuronal networks involves the recruitment of selected neurons into coordinated spatiotemporal activity patterns. This sparse activation results from widespread synaptic inhibition in conjunction with neuron-specific synaptic excitation. We report the selective recruitment of hippocampal pyramidal cells into patterned network activity. During ripple oscillations in awake mice, spiking is much more likely in cells in which the axon originates from a basal dendrite rather than from the soma. High-resolution recordings in vitro and computer modeling indicate that these spikes are elicited by synaptic input to the axon-carrying dendrite and thus escape perisomatic inhibition. Pyramidal cells with somatic axon origin can be activated during ripple oscillations by blocking their somatic inhibition. The recruitment of' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Axon-carrying Dendrite Cell","Hippocampus","Information Processing","Mice","Perisomatic Inhibition","Pyramidal cells","Ripple Oscillations"]} <|eot_id|> | Here is the Description of a dataset. Description:'Information processing in neuronal networks involves the recruitment of selected neurons into coordinated spatiotemporal activity patterns. This sparse activation results from widespread synaptic inhibition in conjunction with neuron-specific synaptic excitation. We report the selective recruitment of hippocampal pyramidal cells into patterned network activity. During ripple oscillations in awake mice, spiking is much more likely in cells in which the axon originates from a basal dendrite rather than from the soma. High-resolution recordings in vitro and computer modeling indicate that these spikes are elicited by synaptic input to the axon-carrying dendrite and thus escape perisomatic inhibition. Pyramidal cells with somatic axon origin can be activated during ripple oscillations by blocking their somatic inhibition. The recruitment of' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Information processing in neuronal networks involves the recruitment of selected neurons into coordinated spatiotemporal activity patterns. This sparse activation results from widespread synaptic inhibition in conjunction with neuron-specific synaptic excitation. We report the selective recruitment of hippocampal pyramidal cells into patterned network activity. During ripple oscillations in awake mice, spiking is much more likely in cells in which the axon originates from a basal dendrite rather than from the soma. High-resolution recordings in vitro and computer modeling indicate that these spikes are elicited by synaptic input to the axon-carrying dendrite and thus escape perisomatic inhibition. Pyramidal cells with somatic axon origin can be activated during ripple oscillations by blocking their somatic inhibition. The recruitment of | Medicine, Health and Life Sciences | Axon-carrying Dendrite Cell; Hippocampus; Information Processing; Mice; Perisomatic Inhibition; Pyramidal cells; Ripple Oscillations |
doi:10.11588/data/KRPJ9A | Image-based screening for stress granule regulators | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The supplied macro provides the opportunity to analyse large-scale image datasets, derived from image-based screening approaches. It can be used as a base for the segmentation of individual cells, referred as regions of interest (ROIs), and the detection and quantification of the stress granule (SG) response within those ROIs' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["ImageJ macro, batch analysis, cell segmentation, SG detection and quantification"]} <|eot_id|> | Here is the Description of a dataset. Description:'The supplied macro provides the opportunity to analyse large-scale image datasets, derived from image-based screening approaches. It can be used as a base for the segmentation of individual cells, referred as regions of interest (ROIs), and the detection and quantification of the stress granule (SG) response within those ROIs' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The supplied macro provides the opportunity to analyse large-scale image datasets, derived from image-based screening approaches. It can be used as a base for the segmentation of individual cells, referred as regions of interest (ROIs), and the detection and quantification of the stress granule (SG) response within those ROIs | Medicine, Health and Life Sciences | ImageJ macro, batch analysis, cell segmentation, SG detection and quantification |
doi:10.11588/data/KS5W0H | NLP in Diagnostic Texts from Nephropathology [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This data set contains all annotated topic word tables from the work 'NLP in Diagnostic Texts from Nephropathology', as well as all pre-processed and tf-idf-vectorized text files. The raw texts (i.e., descriptive and diagnostic sections) are explicitly not made available, since it cannot be ruled out here that it is possible to infer the patient or the person making the report. This is in accordance with our local ethics committee. Please note: This data set is not yet complete and will be completed soon.Please refer to chapter 3.1.2 of our paper to learn how to interpret the annotated topic word tables.The associated gitlab project http://gitlab.medma.uni-heidelberg.de/mlegnar/nlp-in-diagnostic-texts' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["nephropathology","NLP","pathology reports","text analysis","text classification","topic modelling"]} <|eot_id|> | Here is the Description of a dataset. Description:'This data set contains all annotated topic word tables from the work 'NLP in Diagnostic Texts from Nephropathology', as well as all pre-processed and tf-idf-vectorized text files. The raw texts (i.e., descriptive and diagnostic sections) are explicitly not made available, since it cannot be ruled out here that it is possible to infer the patient or the person making the report. This is in accordance with our local ethics committee. Please note: This data set is not yet complete and will be completed soon.Please refer to chapter 3.1.2 of our paper to learn how to interpret the annotated topic word tables.The associated gitlab project http://gitlab.medma.uni-heidelberg.de/mlegnar/nlp-in-diagnostic-texts' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This data set contains all annotated topic word tables from the work 'NLP in Diagnostic Texts from Nephropathology', as well as all pre-processed and tf-idf-vectorized text files. The raw texts (i.e., descriptive and diagnostic sections) are explicitly not made available, since it cannot be ruled out here that it is possible to infer the patient or the person making the report. This is in accordance with our local ethics committee. Please note: This data set is not yet complete and will be completed soon.Please refer to chapter 3.1.2 of our paper to learn how to interpret the annotated topic word tables.The associated gitlab project http://gitlab.medma.uni-heidelberg.de/mlegnar/nlp-in-diagnostic-texts | Medicine, Health and Life Sciences | nephropathology; NLP; pathology reports; text analysis; text classification; topic modelling |
doi:10.11588/data/L45TRX | Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Data accompanying the paper 'Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast' by Buchmuller and Herbst et al, 2019, Nat Communications. This contains raw NGS data for all genotyping analysis in the publication as well as the source code of the castR design software (v1.0)' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["CRISPR-assisted genome engineering","targeted nex-generation sequencing"]} <|eot_id|> | Here is the Description of a dataset. Description:'Data accompanying the paper 'Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast' by Buchmuller and Herbst et al, 2019, Nat Communications. This contains raw NGS data for all genotyping analysis in the publication as well as the source code of the castR design software (v1.0)' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Data accompanying the paper 'Pooled clone collections by multiplexed CRISPR-Cas12a-assisted gene tagging in yeast' by Buchmuller and Herbst et al, 2019, Nat Communications. This contains raw NGS data for all genotyping analysis in the publication as well as the source code of the castR design software (v1.0) | Medicine, Health and Life Sciences | CRISPR-assisted genome engineering; targeted nex-generation sequencing |
doi:10.11588/data/L5J7WO | 3D Focusing in Simple Microfluidic Devices for Continuous-flow Single-cell Imaging [data set] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Accompanying data for the manuscript '3D Focusing in Simple Microfluidic Devices for Continuous-flow Single-cell Imaging'' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Imaging Flow Cytometry","Microfluidics"]} <|eot_id|> | Here is the Description of a dataset. Description:'Accompanying data for the manuscript '3D Focusing in Simple Microfluidic Devices for Continuous-flow Single-cell Imaging'' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Accompanying data for the manuscript '3D Focusing in Simple Microfluidic Devices for Continuous-flow Single-cell Imaging' | Medicine, Health and Life Sciences | Imaging Flow Cytometry; Microfluidics |
doi:10.11588/data/M2TSIT | Neither Carrots nor Sticks? Challenges surrounding Data Sharing from the Perspective of Research Funding Agencies – A Qualitative Expert Interview Study [Interview Excerpts] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy.Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sharing is still not a common practice. Funding agencies tend to facilitate the sharing of research data by both providing incentives and requiring data sharing as part of their policies and conditions for awarding grants. The goal of our article is to answer the following question: What challenges do international funding agencies see when it comes to their own efforts to foster and implement data sharing through their policies?We conducted a series of sixteen guideline-based expert interviews with representatives of leading international funding agencies. As c' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Data Management","Data Sharing","Data Sharing Policies","FAIR Data","Interview study","Qualitative content analysis","Research funders","Research funding agencies"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy.Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sharing is still not a common practice. Funding agencies tend to facilitate the sharing of research data by both providing incentives and requiring data sharing as part of their policies and conditions for awarding grants. The goal of our article is to answer the following question: What challenges do international funding agencies see when it comes to their own efforts to foster and implement data sharing through their policies?We conducted a series of sixteen guideline-based expert interviews with representatives of leading international funding agencies. As c' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy.Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sharing is still not a common practice. Funding agencies tend to facilitate the sharing of research data by both providing incentives and requiring data sharing as part of their policies and conditions for awarding grants. The goal of our article is to answer the following question: What challenges do international funding agencies see when it comes to their own efforts to foster and implement data sharing through their policies?We conducted a series of sixteen guideline-based expert interviews with representatives of leading international funding agencies. As c | Medicine, Health and Life Sciences | Data Management; Data Sharing; Data Sharing Policies; FAIR Data; Interview study; Qualitative content analysis; Research funders; Research funding agencies |
doi:10.11588/data/M2TSIT | Neither Carrots nor Sticks? Challenges surrounding Data Sharing from the Perspective of Research Funding Agencies – A Qualitative Expert Interview Study [Interview Excerpts] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy.Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sharing is still not a common practice. Funding agencies tend to facilitate the sharing of research data by both providing incentives and requiring data sharing as part of their policies and conditions for awarding grants. The goal of our article is to answer the following question: What challenges do international funding agencies see when it comes to their own efforts to foster and implement data sharing through their policies?We conducted a series of sixteen guideline-based expert interviews with representatives of leading international funding agencies. As c' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Data Management","Data Sharing","Data Sharing Policies","FAIR Data","Interview study","Qualitative content analysis","Research funders","Research funding agencies"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy.Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sharing is still not a common practice. Funding agencies tend to facilitate the sharing of research data by both providing incentives and requiring data sharing as part of their policies and conditions for awarding grants. The goal of our article is to answer the following question: What challenges do international funding agencies see when it comes to their own efforts to foster and implement data sharing through their policies?We conducted a series of sixteen guideline-based expert interviews with representatives of leading international funding agencies. As c' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains summaries from interviews with data sharing experts from internationa funding agencies on their organisation's data sharing policy.Data Sharing is widely recognised as crucial for accelerating scientific research and improving its quality. However, data sharing is still not a common practice. Funding agencies tend to facilitate the sharing of research data by both providing incentives and requiring data sharing as part of their policies and conditions for awarding grants. The goal of our article is to answer the following question: What challenges do international funding agencies see when it comes to their own efforts to foster and implement data sharing through their policies?We conducted a series of sixteen guideline-based expert interviews with representatives of leading international funding agencies. As c | Social Sciences | Data Management; Data Sharing; Data Sharing Policies; FAIR Data; Interview study; Qualitative content analysis; Research funders; Research funding agencies |
doi:10.11588/data/M5ZUPP | Translation initiation factor eIF3m controls ubiquitination-dependent early elongation pausing of ribosomes | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of ribosomes on the first 20 codons of mRNA open reading frames. Early elongation pausing results from ubiquitination of the translation machinery including the translation initiation factor eIF3m. We demonstrate that eIF3m is required for efficient early elongation in unstimulated macrophages. The mechanism is of general nature, since eIF3m and ubiquitination control early elongation pausing also in cells outside of the immune system. This work uncovers early elongation as a critical phase during which polypeptide synthesis is actively controlled' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["macrophage activation","mass spectrometry","ubiquitinome analysis"]} <|eot_id|> | Here is the Description of a dataset. Description:'While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of ribosomes on the first 20 codons of mRNA open reading frames. Early elongation pausing results from ubiquitination of the translation machinery including the translation initiation factor eIF3m. We demonstrate that eIF3m is required for efficient early elongation in unstimulated macrophages. The mechanism is of general nature, since eIF3m and ubiquitination control early elongation pausing also in cells outside of the immune system. This work uncovers early elongation as a critical phase during which polypeptide synthesis is actively controlled' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | While translation initiation is extensively regulated, fewer mechanisms are known to control translation elongation. We discovered that prolonged stimulation of macrophages leads to suppression of protein synthesis at the level of translation elongation, through pausing of ribosomes on the first 20 codons of mRNA open reading frames. Early elongation pausing results from ubiquitination of the translation machinery including the translation initiation factor eIF3m. We demonstrate that eIF3m is required for efficient early elongation in unstimulated macrophages. The mechanism is of general nature, since eIF3m and ubiquitination control early elongation pausing also in cells outside of the immune system. This work uncovers early elongation as a critical phase during which polypeptide synthesis is actively controlled | Medicine, Health and Life Sciences | macrophage activation; mass spectrometry; ubiquitinome analysis |
doi:10.11588/data/MYFILV | Structural integration of personality mediates the effects of adverse and protective childhood experiences on the course of psychotherapy [Results] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["ACE","Childhood Experiences","PCE","Psychotherapy Research"]} <|eot_id|> | Here is the Description of a dataset. Description:'Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors | Medicine, Health and Life Sciences | ACE; Childhood Experiences; PCE; Psychotherapy Research |
doi:10.11588/data/MYFILV | Structural integration of personality mediates the effects of adverse and protective childhood experiences on the course of psychotherapy [Results] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["ACE","Childhood Experiences","PCE","Psychotherapy Research"]} <|eot_id|> | Here is the Description of a dataset. Description:'Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors | Other | ACE; Childhood Experiences; PCE; Psychotherapy Research |
doi:10.11588/data/MYFILV | Structural integration of personality mediates the effects of adverse and protective childhood experiences on the course of psychotherapy [Results] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["ACE","Childhood Experiences","PCE","Psychotherapy Research"]} <|eot_id|> | Here is the Description of a dataset. Description:'Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Analysis of the psychotherapy data from the HIP (Heidelberger Institute for Psychotherapy).We checked whether the speed of patients' symptom improvement depended on their childhood experiences. We used the structural integration of personality as mediating factors | Social Sciences | ACE; Childhood Experiences; PCE; Psychotherapy Research |
doi:10.11588/data/NULJJR | Comparison of perfusion models for quantitative T1 weighted DCE-MRI of rectal cancer [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Twenty-six patients with newly diagnosed rectal carcinoma underwent 3T MRI of the pelvis including a T1 weighted dynamic contrast enhanced (DCE) protocol before treatment. For eighteen patients, mean values for Plasma Flow (PF), Plasma Volume (PV) and Mean Transit Time (MTT) were obtained for three perfusion models' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Dynamic contrast-enhanced MRI (DCE MRI)","Pharmacokinetic modelling","Rectal cancer"]} <|eot_id|> | Here is the Description of a dataset. Description:'Twenty-six patients with newly diagnosed rectal carcinoma underwent 3T MRI of the pelvis including a T1 weighted dynamic contrast enhanced (DCE) protocol before treatment. For eighteen patients, mean values for Plasma Flow (PF), Plasma Volume (PV) and Mean Transit Time (MTT) were obtained for three perfusion models' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Twenty-six patients with newly diagnosed rectal carcinoma underwent 3T MRI of the pelvis including a T1 weighted dynamic contrast enhanced (DCE) protocol before treatment. For eighteen patients, mean values for Plasma Flow (PF), Plasma Volume (PV) and Mean Transit Time (MTT) were obtained for three perfusion models | Medicine, Health and Life Sciences | Dynamic contrast-enhanced MRI (DCE MRI); Pharmacokinetic modelling; Rectal cancer |
doi:10.11588/data/NWE2JJ | Histopathology of thymectomy specimens from the MGTX-trial | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Background:The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up:Work-up scheme for the specimens in the MGTX trial [1, 2]. Thymuses were sub-divided into regions that underwent predefined evaluation (e.g. complete work-up of the central A-region, partial work-up of other regions) Content:A xlsx-file with one table for patient data (“dataPatients” with age, gender etc.), one table with histomorphological data for the specimen regions (“dataAllRegions” with gr' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["MGTX"]} <|eot_id|> | Here is the Description of a dataset. Description:'Background:The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up:Work-up scheme for the specimens in the MGTX trial [1, 2]. Thymuses were sub-divided into regions that underwent predefined evaluation (e.g. complete work-up of the central A-region, partial work-up of other regions) Content:A xlsx-file with one table for patient data (“dataPatients” with age, gender etc.), one table with histomorphological data for the specimen regions (“dataAllRegions” with gr' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Background:The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up:Work-up scheme for the specimens in the MGTX trial [1, 2]. Thymuses were sub-divided into regions that underwent predefined evaluation (e.g. complete work-up of the central A-region, partial work-up of other regions) Content:A xlsx-file with one table for patient data (“dataPatients” with age, gender etc.), one table with histomorphological data for the specimen regions (“dataAllRegions” with gr | Medicine, Health and Life Sciences | MGTX |
doi:10.11588/data/NWE2JJ | Histopathology of thymectomy specimens from the MGTX-trial | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Background:The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up:Work-up scheme for the specimens in the MGTX trial [1, 2]. Thymuses were sub-divided into regions that underwent predefined evaluation (e.g. complete work-up of the central A-region, partial work-up of other regions) Content:A xlsx-file with one table for patient data (“dataPatients” with age, gender etc.), one table with histomorphological data for the specimen regions (“dataAllRegions” with gr' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["MGTX"]} <|eot_id|> | Here is the Description of a dataset. Description:'Background:The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up:Work-up scheme for the specimens in the MGTX trial [1, 2]. Thymuses were sub-divided into regions that underwent predefined evaluation (e.g. complete work-up of the central A-region, partial work-up of other regions) Content:A xlsx-file with one table for patient data (“dataPatients” with age, gender etc.), one table with histomorphological data for the specimen regions (“dataAllRegions” with gr' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Background:The thymectomy specimens from the “thymectomy trial in non-thymomatous myasthenia gravis patients receiving prednisone therapy” (MGTX) [1] underwent rigid and comprehensive work-up, which results in a unique, spatially mapped dataset. Fig. 1 Specimen work-up:Work-up scheme for the specimens in the MGTX trial [1, 2]. Thymuses were sub-divided into regions that underwent predefined evaluation (e.g. complete work-up of the central A-region, partial work-up of other regions) Content:A xlsx-file with one table for patient data (“dataPatients” with age, gender etc.), one table with histomorphological data for the specimen regions (“dataAllRegions” with gr | Medicine, Health and Life Sciences | MGTX |
doi:10.11588/data/ORTPJN | Current knowledge on correlations between highly prevalent dental conditions and chronic diseases: an umbrella review [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Introduction: There are existing studies investigating relationships between chronic systemic and dental conditions, but it remains unclear how such knowledge can be used in clinical practice. The present report provides an overview on existing systematic reviews, identifying and evaluating the most frequently reported dental-chronic disease correlations and common risk factors. Methods: A systematic review on existing systematic reviews published between 1995 and 2017 was conducted (umbrella review) and indexed into four databases. The focus was set on the three most prevalent dental conditions and ten chronic systemic diseases with the highest burden of disease in Germany. Two independent reviewers assessed all articles for eligibility, methodological quality using the AMSTAR criteria, and extracted data from' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Chronic disease","Comorbidity","Dental condition","Interdisciplinary care","Multimorbidity","Noncommunicable disease","Oral health","Systematic review","Umbrella review"]} <|eot_id|> | Here is the Description of a dataset. Description:'Introduction: There are existing studies investigating relationships between chronic systemic and dental conditions, but it remains unclear how such knowledge can be used in clinical practice. The present report provides an overview on existing systematic reviews, identifying and evaluating the most frequently reported dental-chronic disease correlations and common risk factors. Methods: A systematic review on existing systematic reviews published between 1995 and 2017 was conducted (umbrella review) and indexed into four databases. The focus was set on the three most prevalent dental conditions and ten chronic systemic diseases with the highest burden of disease in Germany. Two independent reviewers assessed all articles for eligibility, methodological quality using the AMSTAR criteria, and extracted data from' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Introduction: There are existing studies investigating relationships between chronic systemic and dental conditions, but it remains unclear how such knowledge can be used in clinical practice. The present report provides an overview on existing systematic reviews, identifying and evaluating the most frequently reported dental-chronic disease correlations and common risk factors. Methods: A systematic review on existing systematic reviews published between 1995 and 2017 was conducted (umbrella review) and indexed into four databases. The focus was set on the three most prevalent dental conditions and ten chronic systemic diseases with the highest burden of disease in Germany. Two independent reviewers assessed all articles for eligibility, methodological quality using the AMSTAR criteria, and extracted data from | Medicine, Health and Life Sciences | Chronic disease; Comorbidity; Dental condition; Interdisciplinary care; Multimorbidity; Noncommunicable disease; Oral health; Systematic review; Umbrella review |
doi:10.11588/data/P9JEPG | Performance of Covid-19 antigen rapid diagnostic tests for self-testing compared with antigen testing by professionals and molecular tests: A systematic review and meta-analysis [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'ObjectivesSelf-testing is an effective tool to bridge the testing gap for a number of infectious diseas-es; however, its performance using SARS-CoV-2 antigen-detection rapid diagnostic tests (Ag-RDTs) has not been systematically reviewed. We evaluated the accuracy of COVID-19 self-testing and/or self-sampling using Ag-RDTs to inform WHO guideline development.Methods:We searched multiple databases for articles evaluating the accuracy of COVID-19 self-testing or self-sampling through November 19th, 2021. Cohen’s kappa was estimated to as-sess concordance between self-testing/self-sampling and solely professional-use Ag-RDT results. Meta-analysis was performed to obtain pooled performance estimates compared to molecular testing. The QUADAS-2 and GRADE tools were used to evaluate quality and cer-tainty of evidence.Results:Of 12,946 pub' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Ag-RDT","antigen testing","SARS-CoV-2","self testing","systematic review"]} <|eot_id|> | Here is the Description of a dataset. Description:'ObjectivesSelf-testing is an effective tool to bridge the testing gap for a number of infectious diseas-es; however, its performance using SARS-CoV-2 antigen-detection rapid diagnostic tests (Ag-RDTs) has not been systematically reviewed. We evaluated the accuracy of COVID-19 self-testing and/or self-sampling using Ag-RDTs to inform WHO guideline development.Methods:We searched multiple databases for articles evaluating the accuracy of COVID-19 self-testing or self-sampling through November 19th, 2021. Cohen’s kappa was estimated to as-sess concordance between self-testing/self-sampling and solely professional-use Ag-RDT results. Meta-analysis was performed to obtain pooled performance estimates compared to molecular testing. The QUADAS-2 and GRADE tools were used to evaluate quality and cer-tainty of evidence.Results:Of 12,946 pub' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | ObjectivesSelf-testing is an effective tool to bridge the testing gap for a number of infectious diseas-es; however, its performance using SARS-CoV-2 antigen-detection rapid diagnostic tests (Ag-RDTs) has not been systematically reviewed. We evaluated the accuracy of COVID-19 self-testing and/or self-sampling using Ag-RDTs to inform WHO guideline development.Methods:We searched multiple databases for articles evaluating the accuracy of COVID-19 self-testing or self-sampling through November 19th, 2021. Cohen’s kappa was estimated to as-sess concordance between self-testing/self-sampling and solely professional-use Ag-RDT results. Meta-analysis was performed to obtain pooled performance estimates compared to molecular testing. The QUADAS-2 and GRADE tools were used to evaluate quality and cer-tainty of evidence.Results:Of 12,946 pub | Medicine, Health and Life Sciences | Ag-RDT; antigen testing; SARS-CoV-2; self testing; systematic review |
doi:10.11588/data/PJCNTN | Patients’ willingness to provide their clinical data for research purposes and acceptance of different consent models. Findings from a representative survey of cancer patients in Germany [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This is the research data of the publication 'Patients’ willingness to provide their clinical data for research purposes and acceptance of different consent models. Findings from a representative survey of cancer patients in Germany.' The research data includes the questionnaire, the data set used, and a description of the data preparation' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["clinical data","consent","data access","data sharing","health data","international data sharing","patient perspective","private sector","research benefit and control of data","secondary use"]} <|eot_id|> | Here is the Description of a dataset. Description:'This is the research data of the publication 'Patients’ willingness to provide their clinical data for research purposes and acceptance of different consent models. Findings from a representative survey of cancer patients in Germany.' The research data includes the questionnaire, the data set used, and a description of the data preparation' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This is the research data of the publication 'Patients’ willingness to provide their clinical data for research purposes and acceptance of different consent models. Findings from a representative survey of cancer patients in Germany.' The research data includes the questionnaire, the data set used, and a description of the data preparation | Medicine, Health and Life Sciences | clinical data; consent; data access; data sharing; health data; international data sharing; patient perspective; private sector; research benefit and control of data; secondary use |
doi:10.11588/data/PLRQCZ | User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia [data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This data set supports the findings of the FujiLAM qualitative study published in PLOS Global Public Health (Titel:'User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia').The repository contains our de-identified data extracts of our study transcripts after the initial coding step. The analysis memos describe the early phase of analysis after completing the coding process and creating data extracts' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Tuberculosis","Point of Care","Urine LAM","Lipoarabinomannan","FujiLAM","Malawi","Zambia","Qualitative","User Preferences"]} <|eot_id|> | Here is the Description of a dataset. Description:'This data set supports the findings of the FujiLAM qualitative study published in PLOS Global Public Health (Titel:'User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia').The repository contains our de-identified data extracts of our study transcripts after the initial coding step. The analysis memos describe the early phase of analysis after completing the coding process and creating data extracts' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This data set supports the findings of the FujiLAM qualitative study published in PLOS Global Public Health (Titel:'User perspectives and preferences on a novel TB LAM diagnostic (Fujifilm SILVAMP TB LAM) – a qualitative study in Malawi and Zambia').The repository contains our de-identified data extracts of our study transcripts after the initial coding step. The analysis memos describe the early phase of analysis after completing the coding process and creating data extracts | Medicine, Health and Life Sciences | Tuberculosis; Point of Care; Urine LAM; Lipoarabinomannan; FujiLAM; Malawi; Zambia; Qualitative; User Preferences |
doi:10.11588/data/QAHWSF | Synthetic renal ASL MRI [data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Synthetic renal ASL data sets simulating in-vivo acquisitions were generated using body models from the XCAT phantom, the general kinetic model and literature values for tissue properties. Sequence and ASL parameters were set in accordance with the current renal ASL consensus. Five PASL and five PCASL data sets with healthy perfusion and one PCASL data set with abnormal perfusion are available' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["ASL, Perfusion, Kidney"]} <|eot_id|> | Here is the Description of a dataset. Description:'Synthetic renal ASL data sets simulating in-vivo acquisitions were generated using body models from the XCAT phantom, the general kinetic model and literature values for tissue properties. Sequence and ASL parameters were set in accordance with the current renal ASL consensus. Five PASL and five PCASL data sets with healthy perfusion and one PCASL data set with abnormal perfusion are available' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Synthetic renal ASL data sets simulating in-vivo acquisitions were generated using body models from the XCAT phantom, the general kinetic model and literature values for tissue properties. Sequence and ASL parameters were set in accordance with the current renal ASL consensus. Five PASL and five PCASL data sets with healthy perfusion and one PCASL data set with abnormal perfusion are available | Medicine, Health and Life Sciences | ASL, Perfusion, Kidney |
doi:10.11588/data/RDISCE | Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["CTCF","extended ladder model","zinc finger"]} <|eot_id|> | Here is the Description of a dataset. Description:'The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species | Computer and Information Science | CTCF; extended ladder model; zinc finger |
doi:10.11588/data/RDISCE | Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["CTCF","extended ladder model","zinc finger"]} <|eot_id|> | Here is the Description of a dataset. Description:'The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species | Medicine, Health and Life Sciences | CTCF; extended ladder model; zinc finger |
doi:10.11588/data/RDISCE | Prediction and Comparative Analysis of CTCF Binding Sites based on a First Principle Approach [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["CTCF","extended ladder model","zinc finger"]} <|eot_id|> | Here is the Description of a dataset. Description:'The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The file contains the CTCF-DNA binding sites for complete genome of Homo sapiens (human), Mus musculus (mouse), Sus scrofa (pig), Capra hircus (goat), Aedes aegypti (dengue and yellow fever mosquito) and Drosophila melanogaster (fruit fly) using electronic nucleotide alignment. The data analysis is described in NN Oiwa, K Li, CE Cordeiro and DW Heermann, 2022 [arXiv:2110.10508]. Detailed description of the Electronic Nucleotide Alignment method can be found in NN Oiwa, CE Cordeiro, DW Heerman (2016). We also add Caenorhabditis elegans (worm), Plasmodium falciparum (protozoan) and Arabidopsis thaliana (plant) as negative test, since there is not CTCF in these species | Physics | CTCF; extended ladder model; zinc finger |
doi:10.11588/data/RGM2AW | Mapping physical access to healthcare for older adults in sub-Saharan Africa [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This repository contains data, figures and tables created for the paper 'Mapping physical access to healthcare for older adults in sub-Saharan Africa: A cross-sectional analysis with implications for the COVID-19 response', which is currently under review and available as preprint on medRxiv' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["COVID-19 Access healthcare OpenStreetMap AccessMod"]} <|eot_id|> | Here is the Description of a dataset. Description:'This repository contains data, figures and tables created for the paper 'Mapping physical access to healthcare for older adults in sub-Saharan Africa: A cross-sectional analysis with implications for the COVID-19 response', which is currently under review and available as preprint on medRxiv' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This repository contains data, figures and tables created for the paper 'Mapping physical access to healthcare for older adults in sub-Saharan Africa: A cross-sectional analysis with implications for the COVID-19 response', which is currently under review and available as preprint on medRxiv | Earth and Environmental Sciences | COVID-19 Access healthcare OpenStreetMap AccessMod |
doi:10.11588/data/RGM2AW | Mapping physical access to healthcare for older adults in sub-Saharan Africa [Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This repository contains data, figures and tables created for the paper 'Mapping physical access to healthcare for older adults in sub-Saharan Africa: A cross-sectional analysis with implications for the COVID-19 response', which is currently under review and available as preprint on medRxiv' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["COVID-19 Access healthcare OpenStreetMap AccessMod"]} <|eot_id|> | Here is the Description of a dataset. Description:'This repository contains data, figures and tables created for the paper 'Mapping physical access to healthcare for older adults in sub-Saharan Africa: A cross-sectional analysis with implications for the COVID-19 response', which is currently under review and available as preprint on medRxiv' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This repository contains data, figures and tables created for the paper 'Mapping physical access to healthcare for older adults in sub-Saharan Africa: A cross-sectional analysis with implications for the COVID-19 response', which is currently under review and available as preprint on medRxiv | Medicine, Health and Life Sciences | COVID-19 Access healthcare OpenStreetMap AccessMod |
doi:10.11588/data/RR5BMF | Fully-automated quality assurance in multi-center studies using MRI phantom measurements [Dataset] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'43 measurements acquired in eight different sites within the IMAGEN-project, comprising the following 3 T scanner types: Siemens Verio and TimTrio; General Electric Signa Excite, and Signa HDx; Philips Achieva. Additionally one phantom data set was aquired on a 3 T Siemens Skyra resulting in 44 measurements' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Automated quality assurance","MRI","Multicenter study","Phantom measurement"]} <|eot_id|> | Here is the Description of a dataset. Description:'43 measurements acquired in eight different sites within the IMAGEN-project, comprising the following 3 T scanner types: Siemens Verio and TimTrio; General Electric Signa Excite, and Signa HDx; Philips Achieva. Additionally one phantom data set was aquired on a 3 T Siemens Skyra resulting in 44 measurements' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | 43 measurements acquired in eight different sites within the IMAGEN-project, comprising the following 3 T scanner types: Siemens Verio and TimTrio; General Electric Signa Excite, and Signa HDx; Philips Achieva. Additionally one phantom data set was aquired on a 3 T Siemens Skyra resulting in 44 measurements | Medicine, Health and Life Sciences | Automated quality assurance; MRI; Multicenter study; Phantom measurement |
doi:10.11588/data/SYVQMM | Loneliness and diurnal cortisol levels during COVID-19 lockdown: the roles of living situation, relationship status and relationship quality [Research Data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'These data accompany the manuscript 'Loneliness and diurnal cortisol levels during COVID-19 lockdown: the roles of living situation, relationship status and relationship quality'.Abstract: Loneliness and social isolation have become increasing concerns during COVID-19 lockdown through neuroendocrine stress-reactions, physical and mental health problems. We investigated living situation, relationship status and quality as potential moderators for trait and state loneliness and salivary cortisol levels (hormonal stress-responses) in healthy adults during the first lockdown in Germany. N = 1242 participants (mean age = 36.32, 78% female) filled out an online questionnaire on demographics, trait loneliness and relationship quality. Next, N = 247 (mean age = 32.6, 70% female) completed ecological momentary assessment (EMA), collecting twelv' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["cortisol","COVID-19","ecological momentary assessment","living situation","loneliness","romantic relationships"]} <|eot_id|> | Here is the Description of a dataset. Description:'These data accompany the manuscript 'Loneliness and diurnal cortisol levels during COVID-19 lockdown: the roles of living situation, relationship status and relationship quality'.Abstract: Loneliness and social isolation have become increasing concerns during COVID-19 lockdown through neuroendocrine stress-reactions, physical and mental health problems. We investigated living situation, relationship status and quality as potential moderators for trait and state loneliness and salivary cortisol levels (hormonal stress-responses) in healthy adults during the first lockdown in Germany. N = 1242 participants (mean age = 36.32, 78% female) filled out an online questionnaire on demographics, trait loneliness and relationship quality. Next, N = 247 (mean age = 32.6, 70% female) completed ecological momentary assessment (EMA), collecting twelv' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | These data accompany the manuscript 'Loneliness and diurnal cortisol levels during COVID-19 lockdown: the roles of living situation, relationship status and relationship quality'.Abstract: Loneliness and social isolation have become increasing concerns during COVID-19 lockdown through neuroendocrine stress-reactions, physical and mental health problems. We investigated living situation, relationship status and quality as potential moderators for trait and state loneliness and salivary cortisol levels (hormonal stress-responses) in healthy adults during the first lockdown in Germany. N = 1242 participants (mean age = 36.32, 78% female) filled out an online questionnaire on demographics, trait loneliness and relationship quality. Next, N = 247 (mean age = 32.6, 70% female) completed ecological momentary assessment (EMA), collecting twelv | Medicine, Health and Life Sciences | cortisol; COVID-19; ecological momentary assessment; living situation; loneliness; romantic relationships |
doi:10.11588/data/TT4VM3 | Tailored Selection of Study Individuals to be Sequenced in Order to Improve the Accuracy of Genotype Imputation [Source Code] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombination patterns in the study population. By contrast, a maximization of genetic diversity in the reference panel has been recently proposed. We investigate here a novel strategy to select individuals for sequencing that relies on the characterization of the ancestral kernel of the study population. The simulated study scenarios consisted of several combinations of subpopulations from HapMap. HapMap individuals who did not belong to the study population constituted an external reference panel which was complemented with the sequences of study individuals selected' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["genotype imputation","HapMap","reference panel","sequencing","statistical depth"]} <|eot_id|> | Here is the Description of a dataset. Description:'The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombination patterns in the study population. By contrast, a maximization of genetic diversity in the reference panel has been recently proposed. We investigate here a novel strategy to select individuals for sequencing that relies on the characterization of the ancestral kernel of the study population. The simulated study scenarios consisted of several combinations of subpopulations from HapMap. HapMap individuals who did not belong to the study population constituted an external reference panel which was complemented with the sequences of study individuals selected' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombination patterns in the study population. By contrast, a maximization of genetic diversity in the reference panel has been recently proposed. We investigate here a novel strategy to select individuals for sequencing that relies on the characterization of the ancestral kernel of the study population. The simulated study scenarios consisted of several combinations of subpopulations from HapMap. HapMap individuals who did not belong to the study population constituted an external reference panel which was complemented with the sequences of study individuals selected | Medicine, Health and Life Sciences | genotype imputation; HapMap; reference panel; sequencing; statistical depth |
doi:10.11588/data/TT4VM3 | Tailored Selection of Study Individuals to be Sequenced in Order to Improve the Accuracy of Genotype Imputation [Source Code] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombination patterns in the study population. By contrast, a maximization of genetic diversity in the reference panel has been recently proposed. We investigate here a novel strategy to select individuals for sequencing that relies on the characterization of the ancestral kernel of the study population. The simulated study scenarios consisted of several combinations of subpopulations from HapMap. HapMap individuals who did not belong to the study population constituted an external reference panel which was complemented with the sequences of study individuals selected' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["genotype imputation","HapMap","reference panel","sequencing","statistical depth"]} <|eot_id|> | Here is the Description of a dataset. Description:'The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombination patterns in the study population. By contrast, a maximization of genetic diversity in the reference panel has been recently proposed. We investigate here a novel strategy to select individuals for sequencing that relies on the characterization of the ancestral kernel of the study population. The simulated study scenarios consisted of several combinations of subpopulations from HapMap. HapMap individuals who did not belong to the study population constituted an external reference panel which was complemented with the sequences of study individuals selected' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The addition of sequence data from own‐study individuals to genotypes from external data repositories, for example, the HapMap, has been shown to improve the accuracy of imputed genotypes. Early approaches for reference panel selection favored individuals who best reflect recombination patterns in the study population. By contrast, a maximization of genetic diversity in the reference panel has been recently proposed. We investigate here a novel strategy to select individuals for sequencing that relies on the characterization of the ancestral kernel of the study population. The simulated study scenarios consisted of several combinations of subpopulations from HapMap. HapMap individuals who did not belong to the study population constituted an external reference panel which was complemented with the sequences of study individuals selected | Medicine, Health and Life Sciences | genotype imputation; HapMap; reference panel; sequencing; statistical depth |
doi:10.11588/data/W63LJJ | Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients [Analysis] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients'' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Adverse and Protective Childhood Memories","Anxiety Disorders","OPD-2","Psychotherapy Reasearch"]} <|eot_id|> | Here is the Description of a dataset. Description:'This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients'' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | This dataset contains the code for the analysis in R which was used to calculate the results for the study 'Characterization of different types of anxiety disorders according to level of personality functioning and self-reported adverse and positive childhood experiences in a sample of psychotherapy outpatients' | Medicine, Health and Life Sciences | Adverse and Protective Childhood Memories; Anxiety Disorders; OPD-2; Psychotherapy Reasearch |
doi:10.11588/data/X9UEHB | Imputation of Missing Genotypes within LD-Blocks Relying on the Basic Coalescent and Beyond [Source Code] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations. Here we develop a novel approach for genotype imputation in low-recombination regions that relies on the coalescent and permits to explicitly account for population demographic factors.To test the new method, study and reference haplotypes were simulated and gene trees were inferred under the basic coalescent and also considering population growth and structure. The reference haplotypes that first coalesced with study haplotypes were used as templates for genotype imputation. Computer simulations were complemente' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Coalescent theory","Genotype imputation","Imputation accuracy","Linkage disequilibrium","Population growth","Population structure"]} <|eot_id|> | Here is the Description of a dataset. Description:'Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations. Here we develop a novel approach for genotype imputation in low-recombination regions that relies on the coalescent and permits to explicitly account for population demographic factors.To test the new method, study and reference haplotypes were simulated and gene trees were inferred under the basic coalescent and also considering population growth and structure. The reference haplotypes that first coalesced with study haplotypes were used as templates for genotype imputation. Computer simulations were complemente' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations. Here we develop a novel approach for genotype imputation in low-recombination regions that relies on the coalescent and permits to explicitly account for population demographic factors.To test the new method, study and reference haplotypes were simulated and gene trees were inferred under the basic coalescent and also considering population growth and structure. The reference haplotypes that first coalesced with study haplotypes were used as templates for genotype imputation. Computer simulations were complemente | Medicine, Health and Life Sciences | Coalescent theory; Genotype imputation; Imputation accuracy; Linkage disequilibrium; Population growth; Population structure |
doi:10.11588/data/X9UEHB | Imputation of Missing Genotypes within LD-Blocks Relying on the Basic Coalescent and Beyond [Source Code] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations. Here we develop a novel approach for genotype imputation in low-recombination regions that relies on the coalescent and permits to explicitly account for population demographic factors.To test the new method, study and reference haplotypes were simulated and gene trees were inferred under the basic coalescent and also considering population growth and structure. The reference haplotypes that first coalesced with study haplotypes were used as templates for genotype imputation. Computer simulations were complemente' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["Coalescent theory","Genotype imputation","Imputation accuracy","Linkage disequilibrium","Population growth","Population structure"]} <|eot_id|> | Here is the Description of a dataset. Description:'Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations. Here we develop a novel approach for genotype imputation in low-recombination regions that relies on the coalescent and permits to explicitly account for population demographic factors.To test the new method, study and reference haplotypes were simulated and gene trees were inferred under the basic coalescent and also considering population growth and structure. The reference haplotypes that first coalesced with study haplotypes were used as templates for genotype imputation. Computer simulations were complemente' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | Background Genotypes not directly measured in genetic studies are often imputed to improve statistical power and to increase mapping resolution. The accuracy of standard imputation techniques strongly depends on the similarity of linkage disequilibrium (LD) patterns in the study and reference populations. Here we develop a novel approach for genotype imputation in low-recombination regions that relies on the coalescent and permits to explicitly account for population demographic factors.To test the new method, study and reference haplotypes were simulated and gene trees were inferred under the basic coalescent and also considering population growth and structure. The reference haplotypes that first coalesced with study haplotypes were used as templates for genotype imputation. Computer simulations were complemente | Medicine, Health and Life Sciences | Coalescent theory; Genotype imputation; Imputation accuracy; Linkage disequilibrium; Population growth; Population structure |
doi:10.11588/data/Y8UEOY | Auditory cortex activity related to perceptual awareness versus masking of tone sequences [research data] | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'ABSTRACT: Sequences of repeating tones can be masked by other tones of different frequency. When these tone sequences are perceived, nevertheless, a prominent neural response in the auditory cortex is evoked by each tone of the sequence. When the targets are detected based on their isochrony, participants know that they are listening to the target once they detected it. To explore if the neural activity is more closely related to this detection task or to perceptual awareness, this magnetoencephalography (MEG) study used targets that could only be identified with cues provided after or before the masked target. In experiment 1, multiple mono-tone streams with jittered inter-stimulus interval were used, and the tone frequency of the target was indicated by a cue. Results showed no differential auditory cortex activity between hit and mis' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["attention","auditory scene analysis","conscious perception","informational masking","magnetoencephalography","perceptual awareness"]} <|eot_id|> | Here is the Description of a dataset. Description:'ABSTRACT: Sequences of repeating tones can be masked by other tones of different frequency. When these tone sequences are perceived, nevertheless, a prominent neural response in the auditory cortex is evoked by each tone of the sequence. When the targets are detected based on their isochrony, participants know that they are listening to the target once they detected it. To explore if the neural activity is more closely related to this detection task or to perceptual awareness, this magnetoencephalography (MEG) study used targets that could only be identified with cues provided after or before the masked target. In experiment 1, multiple mono-tone streams with jittered inter-stimulus interval were used, and the tone frequency of the target was indicated by a cue. Results showed no differential auditory cortex activity between hit and mis' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | ABSTRACT: Sequences of repeating tones can be masked by other tones of different frequency. When these tone sequences are perceived, nevertheless, a prominent neural response in the auditory cortex is evoked by each tone of the sequence. When the targets are detected based on their isochrony, participants know that they are listening to the target once they detected it. To explore if the neural activity is more closely related to this detection task or to perceptual awareness, this magnetoencephalography (MEG) study used targets that could only be identified with cues provided after or before the masked target. In experiment 1, multiple mono-tone streams with jittered inter-stimulus interval were used, and the tone frequency of the target was indicated by a cue. Results showed no differential auditory cortex activity between hit and mis | Medicine, Health and Life Sciences | attention; auditory scene analysis; conscious perception; informational masking; magnetoencephalography; perceptual awareness |
doi:10.15139/S3/0P513I | The Real-U Follow-Up Study | <|begin_of_text|><|start_header_id|>system<|end_header_id|> You are a research archivist expert in dataset metadata. Answer the question truthfully. <|eot_id|><|start_header_id|>user<|end_header_id|> Here is the Description of a dataset. Description:'The Real Experiences And Lives of University Students (REAL-U) study surveyed 854 UNC-CH college students in 2014-2015 as part of an NIH-funded study to advance data harmonization methods in the study of substance use and related mental health concerns. A subsample also completed a pilot protocol to collect two-weeks of previously sent and received text messages (n=267) to better understand how private digital communication patterns contribute to the social lives of college students. In the summer of 2021, we conducted a follow-up online survey of this subsample to assess post-college substance use and mental health within the context of transitioning to adulthood and the COVID-19 pandemic (resulting n=142). The sample composition reflects efforts to oversample African American students and males and we include more nuanced measures of ' . Please return only a json list of at most 3 Keywords corresponding to the Description:.<|eot_id|><|start_header_id|>assistant<|end_header_id|> {"Answer" : ["alcohol use","anxiety","COVID-19 coping","COVID-19 stressors","depression","drug use","mental health disorders","young adults"]} <|eot_id|> | Here is the Description of a dataset. Description:'The Real Experiences And Lives of University Students (REAL-U) study surveyed 854 UNC-CH college students in 2014-2015 as part of an NIH-funded study to advance data harmonization methods in the study of substance use and related mental health concerns. A subsample also completed a pilot protocol to collect two-weeks of previously sent and received text messages (n=267) to better understand how private digital communication patterns contribute to the social lives of college students. In the summer of 2021, we conducted a follow-up online survey of this subsample to assess post-college substance use and mental health within the context of transitioning to adulthood and the COVID-19 pandemic (resulting n=142). The sample composition reflects efforts to oversample African American students and males and we include more nuanced measures of ' . Please return only a json list of at most 3 Keywords corresponding to the Description:. | The Real Experiences And Lives of University Students (REAL-U) study surveyed 854 UNC-CH college students in 2014-2015 as part of an NIH-funded study to advance data harmonization methods in the study of substance use and related mental health concerns. A subsample also completed a pilot protocol to collect two-weeks of previously sent and received text messages (n=267) to better understand how private digital communication patterns contribute to the social lives of college students. In the summer of 2021, we conducted a follow-up online survey of this subsample to assess post-college substance use and mental health within the context of transitioning to adulthood and the COVID-19 pandemic (resulting n=142). The sample composition reflects efforts to oversample African American students and males and we include more nuanced measures of | Medicine, Health and Life Sciences | alcohol use; anxiety; COVID-19 coping; COVID-19 stressors; depression; drug use; mental health disorders; young adults |
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