Instruments keeps crashing, what could it be?

Instruments 4.2 is crashing about 5 seconds after it starts.  I've set my build configuration to Debug for my profile scheme.  Any suggestions? 
Instruments keeps crashing, what could it be?
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Instruments 4.2 is crashing about 5 seconds after it starts.  I've set my build configuration to Debug for my profile scheme.  Any suggestions? 