Which architecture to use? and why?
I am doing a web based database application for an agency.

The interface will need a very nice drag n drop UI etc (think jQuery UI) and will likely have a large database of users (maybe a few hundred thousand). 

Think of users, where each user has  calendar with drag n drop. The page can be printed etc...


Anyways, Im sure the best architecture depends on the scenario, so:
What is the best architecture to go with ? Why?

I was thinking of going LAMP with jQuery UI. 
But what about python or something? What are the reasons to use one architecture over the other?
Is it noob to use SQL db at that scale? Or do I need oracledb or something

If you need more details to provide an appropriate answer let me know,
Which architecture to use? and why?
===

I am doing a web based database application for an agency.

The interface will need a very nice drag n drop UI etc (think jQuery UI) and will likely have a large database of users (maybe a few hundred thousand). 

Think of users, where each user has  calendar with drag n drop. The page can be printed etc...


Anyways, Im sure the best architecture depends on the scenario, so:
What is the best architecture to go with ? Why?

I was thinking of going LAMP with jQuery UI. 
But what about python or something? What are the reasons to use one architecture over the other?
Is it noob to use SQL db at that scale? Or do I need oracledb or something

If you need more details to provide an appropriate answer let me know,