### ----------------------------------------------------
### -- FHIR
### -- Licenses: Artistic-2.0
### -- Authors: Hugh Simpson
### -- File: t/resources/structureDefinition/EffectEvidenceSynthesis.json
### ----------------------------------------------------
### -- Chunk 12 of 14
" : "A reference to a EvidenceVariable resource that defines the exposure for the research.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.exposure",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/EvidenceVariable"]
      }],
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "EffectEvidenceSynthesis.exposureAlternative",
      "path" : "EffectEvidenceSynthesis.exposureAlternative",
      "short" : "What comparison exposure?",
      "definition" : "A reference to a EvidenceVariable resource that defines the comparison exposure for the research.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.exposureAlternative",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/EvidenceVariable"]
      }],
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "EffectEvidenceSynthesis.outcome",
      "path" : "EffectEvidenceSynthesis.outcome",
      "short" : "What outcome?",
      "definition" : "A reference to a EvidenceVariable resomece that defines the outcome for the research.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.outcome",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/EvidenceVariable"]
      }],
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "EffectEvidenceSynthesis.sampleSize",
      "path" : "EffectEvidenceSynthesis.sampleSize",
      "short" : "What sample size was involved?",
      "definition" : "A description of the size of the sample involved in the synthesis.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.sampleSize",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "Element"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.sampleSize.id",
      "path" : "EffectEvidenceSynthesis.sampleSize.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.sampleSize.extension",
      "path" : "EffectEvidenceSynthesis.sampleSize.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.sampleSize.modifierExtension",
      "path" : "EffectEvidenceSynthesis.sampleSize.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.sampleSize.description",
      "path" : "EffectEvidenceSynthesis.sampleSize.description",
      "short" : "Description of sample size",
      "definition" : "Human-readable summary of sample size.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.sampleSize.description",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
      "path" : "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
      "short" : "How many studies?",
      "definition" : "Number of studies included in this evidence synthesis.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.sampleSize.numberOfStudies",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "integer"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
      "path" : "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
      "short" : "How many participants?",
      "definition" : "Number of participants included in this evidence synthesis.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.sampleSize.numberOfParticipants",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "integer"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure",
      "path" : "EffectEvidenceSynthesis.resultsByExposure",
      "short" : "What was the result per exposure?",
      "definition" : "A description of the results for each exposure considered in the effect estimate.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "EffectEvidenceSynthesis.resultsByExposure",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "Element"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure.id",
      "path" : "EffectEvidenceSynthesis.resultsByExposure.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure.extension",
      "path" : "EffectEvidenceSynthesis.resultsByExposure.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure.modifierExtension",
      "path" : "EffectEvidenceSynthesis.resultsByExposure.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure.description",
      "path" : "EffectEvidenceSynthesis.resultsByExposure.description",
      "short" : "Description of results by exposure",
      "definition" : "Human-readable summary of results by exposure state.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.resultsByExposure.description",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure.exposureState",
      "path" : "EffectEvidenceSynthesis.resultsByExposure.exposureState",
      "short" : "exposure | exposure-alternative",
      "definition" : "Whether these results are for the exposure state or alternative exposure state.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.resultsByExposure.exposureState",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "code"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "ExposureState"
        }],
        "strength" : "required",
        "description" : "Whether the results by exposure is describing the results for the primary exposure of interest (exposure) or the alternative state (exposureAlternative).",
        "valueSet" : "http://hl7.org/fhir/ValueSet/exposure-state|4.0.0"
      }
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure.variantState",
      "path" : "EffectEvidenceSynthesis.resultsByExposure.variantState",
      "short" : "Variant exposure states",
      "definition" : "Used to define variant exposure states such as low-risk state.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.resultsByExposure.variantState",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "EvidenceVariantState"
        }],
        "strength" : "extensible",
        "description" : "Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/evidence-variant-state"
      }
    },
    {
      "id" : "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
      "path" : "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
      "short" : "Risk evidence synthesis",
      "definition" : "Reference to a RiskEvidenceSynthesis resource.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.resultsByExposure.riskEvidenceSynthesis",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/RiskEvidenceSynthesis"]
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate",
      "path" : "EffectEvidenceSynthesis.effectEstimate",
      "short" : "What was the estimated effect",
      "definition" : "The estimated effect of the exposure variant.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "Element"
      }],
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.id",
      "path" : "EffectEvidenceSynthesis.effectEstimate.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.extension",
      "path" : "EffectEvidenceSynthesis.effectEstimate.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.modifierExtension",
      "path" : "EffectEvidenceSynthesis.effectEstimate.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.description",
      "path" : "EffectEvidenceSynthesis.effectEstimate.description",
      "short" : "Description of effect estimate",
      "definition" : "Human-readable summary of effect estimate.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate.description",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.type",
      "path" : "EffectEvidenceSynthesis.effectEstimate.type",
      "short" : "Type of efffect estimate",
      "definition" : "Examples include relative risk and mean difference.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "EffectEstimateType"
        }],
        "strength" : "extensible",
        "description" : "Whether the effect estimate is an absolute effect estimate (absolute difference) or a relative effect estimate (relative difference), and the specific type of effect estimate (eg relative risk or median difference).",
        "valueSet" : "http://hl7.org/fhir/ValueSet/effect-estimate-type"
      }
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.variantState",
      "path" : "EffectEvidenceSynthesis.effectEstimate.variantState",
      "short" : "Variant exposure states",
      "definition" : "Used to define variant exposure states such as low-risk state.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate.variantState",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "EvidenceVariantState"
        }],
        "strength" : "extensible",
        "description" : "Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/evidence-variant-state"
      }
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.value",
      "path" : "EffectEvidenceSynthesis.effectEstimate.value",
      "short" : "Point estimate",
      "definition" : "The point estimate of the effect estimate.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate.value",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "decimal"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
      "path" : "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
      "short" : "What unit is the outcome described in?",
      "definition" : "Specifies the UCUM unit for the outcome.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate.unitOfMeasure",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "UCUMUnits"
        }],
        "strength" : "required",
        "description" : "Unified Code for Units of Measure (UCUM).",
        "valueSet" : "http://hl7.org/fhir/ValueSet/ucum-units|4.0.0"
      }
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
      "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
      "short" : "How precise the estimate is",
      "definition" : "A description of the precision of the estimate for the effect.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "Element"
      }],
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.id",
      "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.extension",
      "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.modifierExtension",
      "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
      "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
      "short" : "Type of precision estimate",
      "definition" : "Examples include confidence interval and interquartile range.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "PrecisionEstimateType"
        }],
        "strength" : "extensible",
        "description" : "Method of reporting variability of estimates, such as confidence intervals, interquartile range or standard deviation.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/precision-estimate-type"
      }
    },
    {
      "id" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level",
      "path" : "EffectEvidenceSynthesis.effectEstimate.precisionEstimate.level",
      "short" : "Level of confidence interval",
      "definition" : "Use 95 for a 95% confidence interval.",
      "min" : 0,
      "max" : "1