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Relavent Documents: Document 0::: Following is a list of dams and reservoirs in Puerto Rico. The below list is incomplete. The National Inventory of Dams, maintained by the U.S. Army Corps of Engineers, defines any "major dam" as being tall with a storage capacity of at least , or of any height with a storage capacity of . Dams and reservoirs in Puerto Rico Lago Caonillas, Utuado, Puerto Rico Electric Power Authority (PREPA) Lago Carite, Guayama, PREPA Carraízo Dam and Lago Loíza, Trujillo Alto, Puerto Rico Aqueducts and Sewers Authority (PRASA) Lago Cerrillos, Ponce, United States Army Corps of Engineers (USACE) Lago de Cidra, Cidra, PRASA Coamo Dam, between Coamo and Santa Isabel, PREPA Lago Dos Bocas, between Arecibo and Utuado municipalities, PREPA Lago Guajataca, between San Sebastián, Quebradillas and Isabela municipalities, PREPA Lago Guayabal, Juana Díaz, PREPA Lago El Guineo (Río Toro Negro), Villalba, PREPA Lago Garzas, Peñuelas, PREPA Lago La Plata, Toa Alta, PRASA Patillas Dam, Patillas, PREPA Portugués Dam, Ponce, USACE Río Blanco Project, Naguabo, PREPA El Salto #1 and El Salto #2, Comerío Lago Toa Vaca, Villalba, PRASA Yauco Project, Yauco, PREPA Gallery See also List of rivers in Puerto Rico References External links USGS List of Reservoirs in Puerto Rico Document 1::: Magnetic 2D materials or magnetic van der Waals materials are two-dimensional materials that display ordered magnetic properties such as antiferromagnetism or ferromagnetism. After the discovery of graphene in 2004, the family of 2D materials has grown rapidly. There have since been reports of several related materials, all except for magnetic materials. But since 2016 there have been numerous reports of 2D magnetic materials that can be exfoliated with ease, similarly to graphene. The first few-layered van der Waals magnetism was reported in 2017 (Cr2Ge2Te6, and CrI3). One reason for this seemingly late discovery is that thermal fluctuations tend to destroy magnetic order for 2D magnets more easily compared to 3D bulk. It is also generally accepted in the community that low dimensional materials have different magnetic properties compared to bulk. This academic interest that transition from 3D to 2D magnetism can be measured has been the driving force behind much of the recent works on van der Waals magnets. Much anticipated transition of such has been since observed in both antiferromagnets and ferromagnets: FePS3, Cr2Ge2Te6, CrI3, NiPS3, MnPS3, Fe3GeTe2 Although the field has been only around since 2016, it has become one of the most active fields in condensed matter physics and materials science and engineering. There have been several review articles written up to highlight its future and promise. Overview Magnetic van der Waals materials is a new addition to the growing list of 2d materials. The special feature of these new materials is that they exhibit a magnetic ground state, either antiferromagnetic or ferromagnetic, when they are thinned down to very few sheets or even one layer of materials. Another, probably more important, feature of these materials is that they can be easily produced in few layers or monolayer form using simple means such as scotch tape, which is rather uncommon among other magnetic materials like oxide magnets. Interest in these Document 2::: Unified Video Decoder (UVD, previously called Universal Video Decoder) is the name given to AMD's dedicated video decoding ASIC. There are multiple versions implementing a multitude of video codecs, such as H.264 and VC-1. UVD was introduced with the Radeon HD 2000 Series and is integrated into some of AMD's GPUs and APUs. UVD occupies a considerable amount of the die surface at the time of its introduction and is not to be confused with AMD's Video Coding Engine (VCE). As of AMD Raven Ridge (released January 2018), UVD and VCE were succeeded by Video Core Next (VCN). Overview The UVD is based on an ATI Xilleon video processor, which is incorporated onto the same die as the GPU and is part of the ATI Avivo HD for hardware video decoding, along with the Advanced Video Processor (AVP). UVD, as stated by AMD, handles decoding of H.264/AVC, and VC-1 video codecs entirely in hardware. The UVD technology is based on the Cadence Tensilica Xtensa processor, which was originally licensed by ATI Technologies Inc. in 2004. UVD/UVD+ In early versions of UVD, video post-processing is passed to the pixel shaders and OpenCL kernels. MPEG-2 decoding is not performed within UVD, but in the shader processors. The decoder meets the performance and profile requirements of Blu-ray and HD DVD, decoding H.264 bitstreams up to a bitrate of 40 Mbit/s. It has context-adaptive binary arithmetic coding (CABAC) support for H.264/AVC. Unlike video acceleration blocks in previous generation GPUs, which demanded considerable host-CPU involvement, UVD offloads the entire video-decoder process for VC-1 and H.264 except for video post-processing, which is offloaded to the shaders. MPEG-2 decode is also supported, but the bitstream/entropy decode is not performed for MPEG-2 video in hardware. Previously, neither ATI Radeon R520 series' ATI Avivo nor NVidia Geforce 7 series' PureVideo assisted front-end bitstream/entropy decompression in VC-1 and H.264 - the host CPU performed this work. UVD han Document 3::: Sliplining is a technique for repairing leaks or restoring structural stability to an existing pipeline. It involves installing a smaller, "carrier pipe" into a larger "host pipe", grouting the annular space between the two pipes, and sealing the ends. Sliplining has been used since the 1940s. The most common material used to slipline an existing pipe is high-density polyethylene (HDPE), but fiberglass-reinforced pipe (FRP) and PVC are also common. Sliplining can be used to stop infiltration and restore structural integrity to an existing pipe. The most common size is (8"-60"), but sliplining can occur in any size given appropriate access and a new pipe small or large enough to install. Installation methods There are two methods used to install a slipline: continuous and segmental. Continuous sliplining uses a long continuous pipe, such as HDPE, Fusible PVC, or Welded Steel Pipe, that are connected into continuous pieces of any length prior to installation. The continuous carrier pipe is pulled through the existing host pipe starting at an insertion pit and continuing to a receiving pit. Either the insertion pit, the receiving pit, or both can be manholes or other existing access points if the size and material of the new carrier pipe can manoeuvre the existing facilities. Segmental sliplining is very similar to continuous sliplining. The difference is primarily based on the pipe material used as the new carrier pipe. When using any bell and spigot pipe such as FRP, PVC, HDPE or Spirally Welded Steel Pipe, the individual pieces of pipe are lowered into place, pushed together, and pushed along the existing pipe corridor. Using either method the annular space between the two pipes must be grouted. In the case of sanitary sewer lines, the service laterals must be reconnected via excavation. Advantages Sliplining is generally a very cost-effective rehabilitation method. It is also very easy to install and requires tools and equipment widely available to any pi The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is a sag in geological terms? A. A raised area of land B. A depressed, persistent, low area C. A type of mountain D. A large body of water Answer:
B. A depressed, persistent, low area
Relavent Documents: Document 0::: Madrid Río is an urban park in the Spanish capital Madrid, built along an urban stretch of the Manzanares River following the burial of the M-30 bypass road in this area. It is the result of a project led by the architect Ginés Garrido, who won the international ideas competition organised by the Madrid City Council in 2005 to redevelop the area. The project started with the idea of recovering the banks of the Manzanares River for the use and enjoyment of the citizens. The section of the river that is now known as Madrid Río is the section that was boxed in by the M-30 bypass road, a road that isolated the river between the two directions of the highway as well as creating a barrier and fracture between the two sides of the city, the district of Arganzuela on the left bank, and the districts of Latina, Carabanchel and Usera on the right bank. The connection of the M-30 with the A-5 motorway, the road to Extremadura, separated the city in an impassable way from Casa de Campo, Madrid's largest park. The project involved the undergrounding of the M-30 in this area as well as that section of the A-5 running parallel to Casa de Campo. There are seven dams that regulate the river as it passes through the city. They receive the waters of the Manzanares River after passing through the Santillana reservoir, in Manzanares el Real, and the El Pardo reservoir, in the municipality of Madrid, which is why they are numbered from 3 to 9. Their mechanisms and locks have been repaired and the dams have been used for the new system of crossings. Initially, the project for the renaturation of the Manzanares River as it passes through Madrid Río contemplated the opening of all the dams, except the last one, to create the conditions that would make it possible for the Madrid Río rowing school to train, but finally, contrary to what was first agreed and due to pressure from the local residents, it was also decided to also open the last one so that the river could flow freely. The water level has been dropped as the natural flow of the river has been restored. Accessible wooden boards and fish ladders have been added to encourage the continuity of the underwater fauna along the river. There has been a noticeable improvement in avian biodiversity along the river with herons and kingfishers being regular visitors. The Madrid Río has received the Veronica Rudge Green Prize in Urban Design from Harvard University's Graduate School of Design in 2015. The architects were Ginés Garrido (of Burgos & Garrido), Porras La Casta, Rubio & Álvarez-Sala, and West 8. Notes External links Document 1::: Digistar is the first computer graphics-based planetarium projection and content system. It was designed by Evans & Sutherland and released in 1983. The technology originally focused on accurate and high quality display of stars, including for the first time showing stars from points of view other than Earth's surface, travelling through the stars, and accurately showing celestial bodies from different times in the past and future. Beginning with the Digistar 3 the system now projects full-dome video. Projector Unlike modern full-dome systems, which use LCD, DLP, SXRD, or laser projection technology, the Digistar projection system was designed for projecting bright pinpoints of light representing stars. This was accomplished using a calligraphic display, a form of vector graphics, rather than raster graphics. The heart of the Digistar projector is a large cathode-ray tube (CRT). A phosphor plate is mounted atop the tube, and light is then dispersed by a large lens with a 160 degree field of view to cover the planetarium dome. The original lens bore the inscription: "August 1979 mfg. by Lincoln Optical Corp., L.A., CA for Evans and Sutherland Computer Corp., SLC, UT, Digital planetarium CRT projection lens, 43mm, f2.8, 160 degree field of view". The coordinates of the stars and wire-frame models to be displayed by the projector were stored in computer RAM in a display list. The display would read each set of coordinates in turn and drive the CRT's electron beam directly to those coordinates. If the electron beam was enabled while being moved a line would be painted on the phosphor plate. Otherwise, the electron beam would be enabled once at its destination and a star would be painted. Once all coordinates in the display list had been processed, the display would repeat from the top of the display list. Thus, the shorter the display list the more frequently the electron beam would refresh the charge on a given point on the phosphor plate, making the projection of t Document 2::: David M. Young Jr. (October 20, 1923 – December 21, 2008) was an American mathematician and computer scientist who was one of the pioneers in the field of modern numerical analysis/scientific computing. Contributions Young is best known for establishing the mathematical framework for iterative methods (a.k.a. preconditioning). These algorithms are now used in computer software on high performance supercomputers for the numerical solution of large sparse linear systems arising from problems involving partial differential equations. See, in particular, the successive over-relaxation (SOR) and symmetric successive over-relaxation (SSOR) methods. When Young first began his research on iterative methods in the late 1940s, there was some skepticism with the idea of using iterative methods on the new computing machines to solve industrial-size problems. Ever since Young's ground-breaking Ph.D. thesis, iterative methods have been used on a wide range of scientific and engineering applications with a variety of new iterative methods having been developed. Education and career Young earned a bachelor's degree in 1944 from the Webb Institute of Naval Architecture. After service in the U.S. Navy during part of World War II, he went to Harvard University to study mathematics and was awarded a master's degree in 1947 and a Ph.D in 1950, working under the supervision of Professor Garrett Birkhoff. Young began his academic career at the University of Maryland, College Park and he was the first to teach a mathematics course focusing mainly on numerical analysis and computer programming. After several years working in the aero-space industry in Los Angeles, he joined the faculty of the University of Texas at Austin, Texas, in 1958. Young was the founding Director of the university Computation Center and then the research Center for Numerical Analysis (CNA) in 1970. He would become the Ashbel Smith Professor of Mathematics and Computer Sciences as well as a founding member of the I Document 3::: Cooling load is the rate at which sensible and latent heat must be removed from the space to maintain a constant space dry-bulb air temperature and humidity. Sensible heat into the space causes its air temperature to rise while latent heat is associated with the rise of the moisture content in the space. The building design, internal equipment, occupants, and outdoor weather conditions may affect the cooling load in a building using different heat transfer mechanisms. The SI units are watts. Overview The cooling load is calculated to select HVAC equipment that has the appropriate cooling capacity to remove heat from the zone. A zone is typically defined as an area with similar heat gains, similar temperature and humidity control requirements, or an enclosed space within a building with the purpose to monitor and control the zone's temperature and humidity with a single sensor e.g. thermostat. Cooling load calculation methodologies take into account heat transfer by conduction, convection, and radiation. Methodologies include heat balance, radiant time series, cooling load temperature difference, transfer function, and sol-air temperature. Methods calculate the cooling load in either steady state or dynamic conditions and some can be more involved than others. These methodologies and others can be found in ASHRAE handbooks, ISO Standard 11855, European Standard (EN) 15243, and EN 15255. ASHRAE recommends the heat balance method and radiant time series methods. Differentiation from heat gains The cooling load of a building should not be confused with its heat gains. Heat gains refer to the rate at which heat is transferred into or generated inside a building. Just like cooling loads, heat gains can be separated into sensible and latent heat gains that can occur through conduction, convection, and radiation. Thermophysical properties of walls, floors, ceilings, and windows, lighting power density (LPD), plug load density, occupant density, and equipment efficiency The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What was the main goal of the Madrid Río project initiated by Ginés Garrido? A. To construct a new highway B. To recover the banks of the Manzanares River for public use C. To build luxury apartments along the river D. To create a dam system for flood prevention Answer:
B. To recover the banks of the Manzanares River for public use
Relavent Documents: Document 0::: In surveying, triangulation is the process of determining the location of a point by measuring only angles to it from known points at either end of a fixed baseline by using trigonometry, rather than measuring distances to the point directly as in trilateration. The point can then be fixed as the third point of a triangle with one known side and two known angles. Triangulation can also refer to the accurate surveying of systems of very large triangles, called triangulation networks. This followed from the work of Willebrord Snell in 1615–17, who showed how a point could be located from the angles subtended from three known points, but measured at the new unknown point rather than the previously fixed points, a problem called resectioning. Surveying error is minimized if a mesh of triangles at the largest appropriate scale is established first. Points inside the triangles can all then be accurately located with reference to it. Such triangulation methods were used for accurate large-scale land surveying until the rise of global navigation satellite systems in the 1980s. Principle Triangulation may be used to find the position of the ship when the positions of A and B are known. An observer at A measures the angle α, while the observer at B measures β. The position of any vertex of a triangle can be calculated if the position of one side, and two angles, are known. The following formulae are strictly correct only for a flat surface. If the curvature of the Earth must be allowed for, then spherical trigonometry must be used. Calculation With being the distance between A and B gives: Using the trigonometric identities tan α = sin α / cos α and sin(α + β) = sin α cos β + cos α sin β, this is equivalent to: therefore: From this, it is easy to determine the distance of the unknown point from either observation point, its north/south and east/west offsets from the observation point, and finally its full coordinates. History Triangulation today is used for Document 1::: In the Taroom district in the Dawson River valley of Queensland, Australia, a boggomoss (pl. boggomossi or boggomosses) is a mound spring. Boggomosses range in form from small muddy swamps to elevated peat bogs or swamps, up to 150 meters across scattered among dry woodland communities, which form part of the Springsure Group of Great Artesian Basin springs. They are rich in invertebrates and form a vital chain of permanently moist oases in an otherwise dry environment. The origin of the term boggomoss is not known, but is most likely a compound of the words bog and moss. "Boggomoss creek" in the Parish of Fernyside appears on very early maps. Environment The spring flow rate is usually in the range of 0.5 to 2.0 litres per second (8th magnitude spring), however some large boggomosses have a flow rate of up to 10.0 litres per second (7th magnitude spring). A report commissioned by the Queensland Department of Environment defined four boggomoss vegetation types with distinct environmental relations: Group 1 associated with sandy and relatively infertile soils. Group 2 associated with fertile and heavy surface soils and relatively large mounds. Group 3 associated with fertile and heavy surface soils, but with little or no mound development (probably young springs). Group 4 are linear in shape and flood prone at the base of a gorge Sources Adclarkia dawsonensis (Boggomoss Snail, Dawson Valley Snail) Document 2::: A col in geomorphology is the lowest point on a mountain ridge between two peaks. It may also be called a gap or pass. Particularly rugged and forbidding cols in the terrain are usually referred to as notches. They are generally unsuitable as mountain passes, but are occasionally crossed by mule tracks or climbers' routes. Derived from the French ("collar, neck") from Latin collum, "neck", the term tends to be associated more with mountain than hill ranges. The distinction with other names for breaks in mountain ridges such as saddle, wind gap or notch is not sharply defined and may vary from place to place. Many double summits are separated by prominent cols. The height of a summit above its highest col (called the key col) is effectively a measure of a mountain's topographic prominence. Cols lie on the line of the watershed between two mountains, often on a prominent ridge or arête. For example, the highest col in Austria, the ("Upper Glockner Col", ) lies between the Kleinglockner () and Grossglockner () mountains, giving the Kleinglockner a minimum prominence of 17 metres. See also Saddle (landform) Document 3::: Mammoplasia is the normal or spontaneous enlargement of human breasts. Mammoplasia occurs normally during puberty and pregnancy in women, as well as during certain periods of the menstrual cycle. When it occurs in males, it is called gynecomastia and is considered to be pathological. When it occurs in females and is extremely excessive, it is called macromastia (also known as gigantomastia or breast hypertrophy) and is similarly considered to be pathological. Mammoplasia may be due to breast engorgement, which is temporary enlargement of the breasts caused by the production and storage of breast milk in association with lactation and/or galactorrhea (excessive or inappropriate production of milk). Mastodynia (breast tenderness/pain) frequently co-occurs with mammoplasia. During the luteal phase (latter half) of the menstrual cycle, due to increased mammary blood flow and/or premenstrual fluid retention caused by high circulating concentrations of estrogen and/or progesterone, the breasts temporarily increase in size, and this is experienced by women as fullness, heaviness, swollenness, and a tingling sensation. Mammoplasia can be an effect or side effect of various drugs, including estrogens, antiandrogens such as spironolactone, cyproterone acetate, bicalutamide, and finasteride, growth hormone, and drugs that elevate prolactin levels such as D2 receptor antagonists like antipsychotics (e.g., risperidone), metoclopramide, and domperidone and certain antidepressants like selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs). The risk appears to be less with serotonin-norepinephrine reuptake inhibitors (SNRIs) like venlafaxine. The "atypical" antidepressants mirtazapine and bupropion do not increase prolactin levels (bupropion may actually decrease prolactin levels), and hence there may be no risk with these agents. Other drugs that have been associated with mammoplasia include D-penicillamine, bucillamine, neothetazone, ciclosporin, The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the main argument presented by critics of the GAARlandia hypothesis regarding the colonization of the Greater Antilles? A. They support the hypothesis based on geological evidence. B. They believe oceanic dispersal is the best explanation for colonization. C. They argue that multiple lineages colonized simultaneously. D. They find ample support from studies of individual lineages. Answer:
B. They believe oceanic dispersal is the best explanation for colonization.
Relavent Documents: Document 0::: Glycoprotein 130 (also known as gp130, IL6ST, IL6R-beta or CD130) is a transmembrane protein which is the founding member of the class of tall cytokine receptors. It forms one subunit of the type I cytokine receptor within the IL-6 receptor family. It is often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement. As with other type I cytokine receptors, gp130 possesses a WSXWS amino acid motif that ensures correct protein folding and ligand binding. It interacts with Janus kinases to elicit an intracellular signal following receptor interaction with its ligand. Structurally, gp130 is composed of five fibronectin type-III domains and one immunoglobulin-like C2-type (immunoglobulin-like) domain in its extracellular portion. Characteristics The members of the IL-6 receptor family are all complex with gp130 for signal transduction. For example, IL-6 binds to the IL-6 Receptor. The complex of these two proteins then associates with gp130. This complex of 3 proteins then homodimerizes to form a hexameric complex which can produce downstream signals. There are many other proteins which associate with gp130, such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There are also several other proteins which have structural similarity to gp130 and contain the WSXWS motif and preserved cysteine residues. Members of this group include LIF-R, OSM-R, and G-CSF-R. Loss of gp130 gp130 is an important part of many different types of signaling complexes. Inactivation of gp130 is lethal to mice. Homozygous mice who are born show a number of defects including impaired development of the ventricular myocardium. Haematopoietic effects included reduced numbers of stem cells in the spleen and liver. Signal transduction gp130 has no intrinsic tyrosine kinase activity. Instead, it is phosphorylated on tyrosine residues after complexing with other Document 1::: Peter Cameron (1847 – 1 December 1912 in New Mills, Derbyshire) was an English amateur entomologist who specialised in Hymenoptera. An artist, Cameron worked in the dye industry and in calico printing. He described many new species; his collection, including type material, is now in the Natural History Museum. He suffered from poor health and lack of employment. Latterly, he lived in New Mills and was supported by scholarships from the Royal Society. He loaned specimens to Jean-Jacques Kieffer, a teacher and Catholic priest in Bitche, Lorraine, who also named species after Cameron. Some of Cameron's taxonomic work is not very well regarded. Upon his death Claude Morley wrote, "Peter Cameron is dead, as was announced by most of the halfpenny papers on December 4th. What can we say of his life? Nothing; for it concerns us in no way. What shall we say of his work? Much, for it is entirely ours, and will go down to posterity as probably the most prolific and chaotic output of any individual for many years past." Similarly, American entomologist Richard M. Bohart "wound up with the thankless task of sorting through Cameron's North American contributions to a small group of wasps known as the Odynerini. Of the hundred or so names Cameron proposed within the group, almost all, Bohart found, were invalid." The Panamanian oak gall wasp Callirhytis cameroni described 2014 is named in his honor. Works A Monograph of the British Phytophagous Hymenoptera Ray Society (1882–1893) Hymenoptera volumes of the Biologia Centrali-Americana, volumes 1–2 (1883–1900) and (1888–1900) A complete list is given in external links below. External links Publications of Peter Cameron Manuscript collection BHL Hymenoptera Orientalis: or contributions to a knowledge of the Hymenoptera of the Oriental zoological region. Manchester :Literary and Philosophical Society,1889–1903. Digital Version of Biologia Centrali-Americana Document 2::: Buildings and structures Buildings c. 1250 Western towers and north rose window of Notre Dame de Paris in the Kingdom of France are built. Hexham Abbey, England completed (begun c. 1170). Konark Sun Temple in Odisha built. 1250 Château de Spesbourg, Holy Roman Empire built. Ponts Couverts, Strasbourg, opened. 1252 – Church of Alcobaça Monastery in Portugal completed. c. 1252 – The Franciscan abbey of Claregalway Friary, in Claregalway, County Galway, Ireland is commissioned by Norman knight John de Cogan. 1253 – Construction of the upper Basilica of San Francesco d'Assisi in Assisi, designed by Elia Bombardone, is completed. 1255 – New Gothic choir of the Tournai Cathedral in the Kingdom of France built. 1256 – Construction of Hermann Castle in present-day Estonia is started. 1257 – Construction of the Basilica di Santa Chiara in Assisi begun. 1258 – The main body of the Salisbury Cathedral (begun in 1220) in Salisbury, England, is completed. Births c. 1250 Giovanni Pisano, Italian sculptor, painter, and architect (d. c. 1315) Deaths none listed References Document 3::: Sonata was a 3D building design software application developed in the early 1980s and now regarded as the forerunner of today's building information modeling applications. Sonata was commercially released in 1986, having been developed by Jonathan Ingram independently and was sold to T2 Solutions (renamed from GMW Computers in 1987 - which was eventually bought by Alias|Wavefront), and was sold as a successor to GMW's RUCAPS. It ran on workstation computer hardware (by contrast, other 2D computer-aided design (CAD) systems could run on personal computers). The system was not expensive, according to Michael Phiri. Reiach Hall purchased "three Sonata workstations on Silicon Graphics machines, at a total cost of approximately £2000 each" [1990 prices]. Approximately 1,000 seats were sold between 1985 and 1992. However, as a BIM application, in addition to geometric modelling, it could model complete buildings, including complex parametrics, costs and staging of the construction process. Archicad founder Gábor Bojár has acknowledged that Sonata "was more advanced in 1986 than Archicad at that time", adding that it "surpassed already the matured definition of 'BIM' specified only about one and a half decade later". Many projects were designed and built using Sonata, including Peddle Thorp Architect's Rod Laver Arena in 1987, and Gatwick Airport North Terminal Domestic Facility by Taylor Woodrow. The US-based architect HKS used the software in 1992 to design a horse racing facility (Lone Star Park in Grand Prairie, Texas) and subsequently purchased the successor product, Reflex. Target Australia Pty. Ltd. the Australian discount department store retailer bought two Sonata licences in 1992 to replace two RUCAPS workstations originally from Coles Supermarkets. The software was run on two Silicon Graphics IRIS Indigo workstations. Staff were trained to use the software including the parametric language. The simple but powerful parametrics enable productivity gains in doc The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What significant event occurred in 2006 regarding Inspur's branding? A. Inspur changed its name from Langchao. B. Inspur was acquired by Microsoft. C. Inspur launched its first cloud computing product. D. Inspur established a joint venture with VMware. Answer:
A. Inspur changed its name from Langchao.
Relavent Documents: Document 0::: EL Aquilae, also known as Nova Aquilae 1927 was a nova that appeared in 1927. It was discovered by Max Wolf on photographic plates taken at Heidelberg Observatory on 30 and 31 July 1927 when it had a photographic magnitude of 9. Subsequent searches of plates taken at the Harvard College Observatory showed the nova was fainter than magnitude 11.1 on 8 June 1927 and had flared to magnitude 6.4 on 15 June 1927. It declined from peak brightness at an average rate of 0.105 magnitudes per day, making it a fast nova, and ultimately dimmed to about magnitude 21. The 14.5 magnitude change from peak brightness to quiescence was unusually large for a nova. All novae are binary stars, with a "donor" star orbiting a white dwarf so closely that matter is transferred from the donor to the white dwarf. Pagnotta & Schaefer argued that the donor star for the EL Aquilae system is a red giant, based on its position in an infrared color–color diagram. Tappert et al. suggest that Pagnotta & Schaefer misidentified EL Aquilae, and claim that EL Aquilae is probably an intermediate polar, a nova with a main sequence donor star, based on its eruption amplitude and color. Notes References Document 1::: The Barton decarboxylation is a radical reaction in which a carboxylic acid is converted to a thiohydroxamate ester (commonly referred to as a Barton ester). The product is then heated in the presence of a radical initiator and a suitable hydrogen donor to afford the decarboxylated product. This is an example of a reductive decarboxylation. Using this reaction it is possible to remove carboxylic acid moieties from alkyl groups and replace them with other functional groups. (See Scheme 1) This reaction is named after its developer, the British chemist and Nobel laureate Sir Derek Barton (1918–1998). Mechanism The reaction is initiated by homolytic cleavage of a radical initiator, in this case 2,2'-azobisisobutyronitrile (AIBN), upon heating. A hydrogen is then abstracted from the hydrogen source (tributylstannane in this case) to leave a tributylstannyl radical that attacks the sulfur atom of the thiohydroxamate ester. The N-O bond of the thiohydroxamate ester undergoes homolysis to form a carboxyl radical which then undergoes decarboxylation and carbon dioxide (CO2) is lost. The remaining alkyl radical (R·) then abstracts a hydrogen atom from remaining tributylstannane to form the reduced alkane (RH). (See Scheme 2) The tributyltin radical enters into another cycle of the reaction until all thiohydroxamate ester is consumed. N-O bond cleavage of the Barton ester can also occur spontaneously upon heating or by irradiation with light to initiate the reaction. In this case a radical initiator is not required but a hydrogen-atom (H-atom) donor is still necessary to form the reduced alkane (RH). Alternative H-atom donors to tributylstannane include tertiary thiols and organosilanes. The relative expense, smell, and toxicity associated with tin, thiol or silane reagents can be avoided by carrying the reaction out using chloroform as both solvent and H-atom donor. It is also possible to functionalize the alkyl radical by use of other radical trapping species (X-Y + R· Document 2::: Before data.europa.eu, the EU Open Data Portal was the point of access to public data published by the EU institutions, agencies and other bodies. On April 21, 2021 it was consolidated to the data.europa.eu portal, together with the European Data Portal: a similar initiative aimed at the EU Member States. Public data can be used and reused for commercial or non‑commercial purposes. The portal was a key instrument of the EU open data strategy. By ensuring easy and free access to data, their innovative use and economic potential can be enhanced. The goal of the portal was also to make the institutions and other EU bodies more transparent and accountable. Legal basis and launch of the portal Launched in December 2012, the portal was formally established by Commission Decision of 12 December 2011 (2011/833/EU) on the reuse of Commission documents to promote accessibility and reuse. Based on this decision, all the EU institutions were invited - and are still today - to publish information such as open data and to make it accessible to the public whenever possible. The operational management of the portal was the task of the Publications Office of the European Union. Implementation of EU open data policy was the responsibility of the Directorate General for Communications Networks, Content and Technology (DG CONNECT) of the European Commission. This is still true today with data.europa.eu. Features The portal enabled users to search, explore, link, download and easily re-use data for commercial or non-commercial purposes, through a common metadata catalogue. From the portal, users could access data published on the websites of the various institutions, agencies and other bodies of the EU. Semantic technologies offered additional functionalities. The metadata catalogue could be searched via an interactive search engine and through SPARQL queries. Users could suggest data they think is missing on the portal and give feedback on the quality of data obtainable. The Document 3::: The Eastern Trough Area Project, commonly known as ETAP, is a network of nine smaller oil and gas fields in the Central North Sea covering an area up to 35 km in diameter. There are a total of nine different fields, six operated by BP and another three operated by Shell, and together, they are a rich mix of geology, chemistry, technology and equity arrangements. Development The ETAP complex was sanctioned for development in 1995 with first hydrocarbons produced in 1998. The original development included Marnock, Mungo, Monan and Machar from BP and Heron, Egret, Skua from Shell. In 2002, BP brought Mirren and Madoes on stream. With these nine fields, the total reserves of ETAP are approximately of oil, of natural gas condensate and of natural gas. A single central processing facility (CPF) sits over the Marnock field and serves as a hub for all production and operations of the asset including all processing and export and a base for expedition to the Mungo NUI. The CPF consists of separate platforms for operations and accommodation linked by two 60 m bridges. The Processing, drilling and Riser platform (PdR), contains the process plant and the export lines, a riser area to receive production fluids from the other ETAP fields and the wellheads of Marnock. The Quarters and Utilities platform (QU) provides accommodation for up to 157 personnel operating this platform or travelling onwards to the Mungo NUI. This partitioning of accommodation and operations into two platforms, adds an extra element of safety, a particular concern for the designers coming only a few years after the Cullen report on the Piper Alpha disaster. Liquids are exported to Kinneil at Grangemouth through the Forties pipeline system. Gas is exported by the Central Area Transmission System to Teesside. Apart from Mungo, which has surface wellheads on a NUI, all other fields use subsea tie-backs. A tenth field, Fidditch, is currently under development by BP. (which has now been put on The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the maximum transfer rate of the HP Precision bus in burst mode? A. 23 MB/s B. 32 MB/s C. 5 MB/s D. 8 MB/s Answer:
A. 23 MB/s
Relavent Documents: Document 0::: Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue). Weight loss can either occur unintentionally because of malnourishment or an underlying disease, or from a conscious effort to improve an actual or perceived overweight or obese state. "Unexplained" weight loss that is not caused by reduction in calorific intake or increase in exercise is called cachexia and may be a symptom of a serious medical condition. Intentional Intentional weight loss is the loss of total body mass as a result of efforts to improve fitness and health, or to change appearance through slimming. Weight loss is the main treatment for obesity, and there is substantial evidence this can prevent progression from prediabetes to type 2 diabetes with a 7–10% weight loss and manage cardiometabolic health for diabetic people with a 5–15% weight loss. Weight loss in individuals who are overweight or obese can reduce health risks, increase fitness, and may delay the onset of diabetes. It could reduce pain and increase movement in people with osteoarthritis of the knee. Weight loss can lead to a reduction in hypertension (high blood pressure), however whether this reduces hypertension-related harm is unclear. Weight loss is achieved by adopting a lifestyle in which fewer calories are consumed than are expended. Depression, stress or boredom may contribute to unwanted weight gain or loss depending on the individual, and in these cases, individuals are advised to seek medical help. A 2010 study found that dieters who got a full night's sleep lost more than twice as much fat as sleep-deprived dieters. Though hypothesized that supplementation of vitamin D may help, studies do not support this. The majority of dieters regain weight over the long term. According to the UK National Health Service and the Di Document 1::: Arthur Mellen Wellington (December 20, 1847 – May 17, 1895) was an American civil engineer who wrote the 1877 book The Economic Theory of the Location of Railways. The saying that An engineer can do for a dollar what any fool can do for two is an abridgement of a statement made in this work (see below). Wellington was involved in the design and construction of new railways in Mexico. He was chief engineer of the Toledo and Canada Southern Railroad. He was the editor of the Engineering News. The pioneering effort of Wellington in engineering economics in the 1870s was continued by John Charles Lounsbury Fish with the publication of Engineering Economics: First Principles in 1923 and the first publication of the Principles of Engineering Economy in 1930 by Eugene L. Grant. Early life and works He was born on December 25, 1847, in Waltham, Massachusetts. In 1878, he married Agnes Bates, and they had two children. Wellington was a descendant of Roger Wellington, an early settler of the Massachusetts Bay Colony in 1636 and Benjamin Wellington. In 1863, Wellington graduated from the Boston Latin School and then studied engineering with John Benjamin Henck, a prominent civil engineer practicing in Boston. While his work with Henck took place during the American Civil War, he studied mechanical engineering and passed the examination for an assistant engineer in the United States Navy but with the end of the War, never received an appointment. Surveyor and locating engineer Wellington left Henck's office in 1866 to work as a surveyor in the engineers corps at the Brooklyn Parks department on the Prospect Park project under Frederick Law Olmsted. In 1868, he took a position as a surveyor on a locating party for the Blue Ridge railroad in South Carolina in charge of a series of explorations to find possible routes for the railroad. Wellington left the South Carolina road and went on to practice location engineering for the Dutchess & Columbia railroad in New York state. He Document 2::: This page provides supplementary chemical data on vitexin. Material Safety Data Sheet The handling of this chemical may incur notable safety precautions. It is highly recommend that you seek the Material Safety Datasheet (MSDS) for this chemical from a reliable source such as eChemPortal, and follow its directions. Sigma Aldrich MSDS from SDSdata.org Spectral data References Document 3::: In the hyperbolic plane, as in the Euclidean plane, each point can be uniquely identified by two real numbers. Several qualitatively different ways of coordinatizing the plane in hyperbolic geometry are used. This article tries to give an overview of several coordinate systems in use for the two-dimensional hyperbolic plane. In the descriptions below the constant Gaussian curvature of the plane is −1. Sinh, cosh and tanh are hyperbolic functions. Polar coordinate system The polar coordinate system is a two-dimensional coordinate system in which each point on a plane is determined by a distance from a reference point and an angle from a reference direction. The reference point (analogous to the origin of a Cartesian system) is called the pole, and the ray from the pole in the reference direction is the polar axis. The distance from the pole is called the radial coordinate or radius, and the angle is called the angular coordinate, or polar angle. From the hyperbolic law of cosines, we get that the distance between two points given in polar coordinates is Let , differentiating at : we get the corresponding metric tensor: The straight lines are described by equations of the form where r0 and θ0 are the coordinates of the nearest point on the line to the pole. Quadrant model system The Poincaré half-plane model is closely related to a model of the hyperbolic plane in the quadrant Q = {(x,y): x > 0, y > 0}. For such a point the geometric mean and the hyperbolic angle produce a point (u,v) in the upper half-plane. The hyperbolic metric in the quadrant depends on the Poincaré half-plane metric. The motions of the Poincaré model carry over to the quadrant; in particular the left or right shifts of the real axis correspond to hyperbolic rotations of the quadrant. Due to the study of ratios in physics and economics where the quadrant is the universe of discourse, its points are said to be located by hyperbolic coordinates. Cartesian-style coordinate systems I The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What does the term "xystum" refer to in architecture? A. A covered portico of a gymnasium B. An open path or promenade C. A type of decorative wall D. A specific style of basilica Answer:
B. An open path or promenade
Relavent Documents: Document 0::: A deadband or dead-band (also known as a dead zone or a neutral zone) is a band of input values in the domain of a transfer function in a control system or signal processing system where the output is zero (the output is 'dead' - no action occurs). Deadband regions can be used in control systems such as servoamplifiers to prevent oscillation or repeated activation-deactivation cycles (called 'hunting' in proportional control systems). A form of deadband that occurs in mechanical systems, compound machines such as gear trains is backlash. Voltage regulators In some power substations there are regulators that keep the voltage within certain predetermined limits, but there is a range of voltage in-between during which no changes are made, such as between 112 and 118 volts (the deadband is 6 volts), or between 215 and 225 volts (deadband is 10 volts). Backlash Gear teeth with slop (backlash) exhibit deadband. There is no drive from the input to the output shaft in either direction while the teeth are not meshed. Leadscrews generally also have backlash and hence a deadband, which must be taken into account when making position adjustments, especially with CNC systems. If mechanical backlash eliminators are not available, the control can compensate for backlash by adding the deadband value to the position vector whenever direction is reversed. Hysteresis versus Deadband Deadband is different from hysteresis. With hysteresis, there is no deadband and so the output is always in one direction or another. Devices with hysteresis have memory, in that previous system states dictate future states. Examples of devices with hysteresis are single-mode thermostats and smoke alarms. Deadband is the range in a process where no changes to output are made. Hysteresis is the difference in a variable depending on the direction of travel. Thermostats Simple (single mode) thermostats exhibit hysteresis. For example, the furnace in the basement of a house is adjusted automatically by Document 1::: A micronucleus is a small nucleus that forms whenever a chromosome or a fragment of a chromosome is not incorporated into one of the daughter nuclei during cell division. It usually is a sign of genotoxic events and chromosomal instability. Micronuclei are commonly seen in cancerous cells and may indicate genomic damage events that can increase the risk of developmental or degenerative diseases. Micronuclei form during anaphase from lagging acentric chromosomes or chromatid fragments caused by incorrectly repaired or unrepaired DNA breaks or by nondisjunction of chromosomes. This improper segregation of chromosomes may result from hypomethylation of repeat sequences present in pericentromeric DNA, irregularities in kinetochore proteins or their assembly, a dysfunctional spindle apparatus, or flawed anaphase checkpoint genes. Micronuclei can contribute to genome instability by promoting a catastrophic mutational event called chromothripsis. Many micronucleus assays have been developed to test for the presence of these structures and determine their frequency in cells exposed to certain chemicals or subjected to stressful conditions. The term micronucleus may also refer to the smaller nucleus in ciliate protozoans, such as the Paramecium. In mitosis it divides by fission, and in conjugation a pair of gamete micronuclei undergo reciprocal fusion to form a zygote nucleus, which gives rise to the macronuclei and micronuclei of the individuals of the next cycle of fission. Discovery Micronuclei in newly formed red blood cells in humans are known as Howell-Jolly bodies because these structures were first identified and described in erythrocytes by hematologists William Howell and Justin Jolly. These structures were later found to be associated with deficiencies in vitamins such as folate and B12. The relationship between formation of micronuclei and exposure to environmental factors was first reported in root tip cells exposed to ionizing radiation. Micronucleus inducti Document 2::: Controlled vocabularies provide a way to organize knowledge for subsequent retrieval. They are used in subject indexing schemes, subject headings, thesauri, taxonomies and other knowledge organization systems. Controlled vocabulary schemes mandate the use of predefined, preferred terms that have been preselected by the designers of the schemes, in contrast to natural language vocabularies, which have no such restriction. In library and information science In library and information science, controlled vocabulary is a carefully selected list of words and phrases, which are used to tag units of information (document or work) so that they may be more easily retrieved by a search. Controlled vocabularies solve the problems of homographs, synonyms and polysemes by a bijection between concepts and preferred terms. In short, controlled vocabularies reduce unwanted ambiguity inherent in normal human languages where the same concept can be given different names and ensure consistency. For example, in the Library of Congress Subject Headings (a subject heading system that uses a controlled vocabulary), preferred terms—subject headings in this case—have to be chosen to handle choices between variant spellings of the same word (American versus British), choice among scientific and popular terms (cockroach versus Periplaneta americana), and choices between synonyms (automobile versus car), among other difficult issues. Choices of preferred terms are based on the principles of user warrant (what terms users are likely to use), literary warrant (what terms are generally used in the literature and documents), and structural warrant (terms chosen by considering the structure, scope of the controlled vocabulary). Controlled vocabularies also typically handle the problem of homographs with qualifiers. For example, the term pool has to be qualified to refer to either swimming pool or the game pool to ensure that each preferred term or heading refers to only one concept. Types u Document 3::: The Brendel–Bormann oscillator model is a mathematical formula for the frequency dependence of the complex-valued relative permittivity, sometimes referred to as the dielectric function. The model has been used to fit to the complex refractive index of materials with absorption lineshapes exhibiting non-Lorentzian broadening, such as metals and amorphous insulators, across broad spectral ranges, typically near-ultraviolet, visible, and infrared frequencies. The dispersion relation bears the names of R. Brendel and D. Bormann, who derived the model in 1992, despite first being applied to optical constants in the literature by Andrei M. Efimov and E. G. Makarova in 1983. Around that time, several other researchers also independently discovered the model. The Brendel-Bormann oscillator model is aphysical because it does not satisfy the Kramers–Kronig relations. The model is non-causal, due to a singularity at zero frequency, and non-Hermitian. These drawbacks inspired J. Orosco and C. F. M. Coimbra to develop a similar, causal oscillator model. Mathematical formulation The general form of an oscillator model is given by where is the relative permittivity, is the value of the relative permittivity at infinite frequency, is the angular frequency, is the contribution from the th absorption mechanism oscillator. The Brendel-Bormann oscillator is related to the Lorentzian oscillator and Gaussian oscillator , given by where is the Lorentzian strength of the th oscillator, is the Lorentzian resonant frequency of the th oscillator, is the Lorentzian broadening of the th oscillator, is the Gaussian broadening of the th oscillator. The Brendel-Bormann oscillator is obtained from the convolution of the two aforementioned oscillators in the manner of , which yields where is the Faddeeva function, . The square root in the definition of must be taken such that its imaginary component is positive. This is achieved by: The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What was the primary cause of the Gerrards Cross Tunnel collapse as confirmed by a later investigation in 2022? A. Heavy rainfall B. Insufficient safety checks C. Backfilling operation D. Design flaws Answer:
C. Backfilling operation
Relavent Documents: Document 0::: 4 Camelopardalis is a probable multiple star in the northern constellation of Camelopardalis, located 177 light years away from the Sun, based upon parallax. With a combined apparent visual magnitude of 5.29, it is visible to the naked eye as a faint, white-hued star. The pair have a relatively high proper motion, traversing the celestial sphere at an angular rate of per year. The system's proper motion makes it a candidate for membership in the IC 2391 supercluster. They are moving away from the Earth with a heliocentric radial velocity of 22.5 km/s. The brighter member, designated component A, is classified as an Am star, which indicates that the spectrum shows abnormalities of certain elements. It is an estimated 560 million years old and is spinning with a projected rotational velocity of 75 The star has 2.01 times the mass of the Sun and 2.57 times the Sun's radius. It is radiating 18 times the Sun's luminosity from its photosphere at an effective temperature of 7,700 K. There is a faint, magnitude 9.49 companion at an angular separation of – component B; the pair most likely form a binary systemwith a period of about 90 years. There is also a 13th-magnitude visual companion away which shares a common proper motion and parallax. Another listed companion, a 12th-magnitude star nearly away, is probably unrelated. References External links HR 1511 CCDM J04480+5645 Image 4 Camelopardalis Document 1::: AIMStar was a proposed antimatter-catalyzed nuclear pulse propulsion craft that uses clouds of antiprotons to initiate fission and fusion within fuel pellets. A magnetic nozzle derives motive force from the resulting explosions. The design was studied during the 1990s by Penn State University. The craft was designed to reach a distance on the order of 10,000 AU from the Sun, with a travel time of 50 years, and a coasting velocity of approximately 960 km/s after the boost phase (roughly 1/300th of the speed of light). The probe would be able to study the interstellar medium as well as reach Alpha Centauri. The project would require more antimatter than we are capable of producing. In addition, some technical hurdles need to be surpassed before it would be feasible. See also ICAN-II - A similar concept that uses less antimatter but more fission propellant Nuclear pulse propulsion References External links Antimatter (PSU) Document 2::: Structural complexity is a science of applied mathematics that aims to relate fundamental physical or biological aspects of a complex system with the mathematical description of the morphological complexity that the system exhibits, by establishing rigorous relations between mathematical and physical properties of such system. Structural complexity emerges from all systems that display morphological organization. Filamentary structures, for instance, are an example of coherent structures that emerge, interact and evolve in many physical and biological systems, such as mass distribution in the Universe, vortex filaments in turbulent flows, neural networks in our brain and genetic material (such as DNA) in a cell. In general information on the degree of morphological disorder present in the system tells us something important about fundamental physical or biological processes. Structural complexity methods are based on applications of differential geometry and topology (and in particular knot theory) to interpret physical properties of dynamical systems. such as relations between kinetic energy and tangles of vortex filaments in a turbulent flow or magnetic energy and braiding of magnetic fields in the solar corona, including aspects of topological fluid dynamics. Literature References Document 3::: {{DISPLAYTITLE:Lp space}} In mathematics, the spaces are function spaces defined using a natural generalization of the -norm for finite-dimensional vector spaces. They are sometimes called Lebesgue spaces, named after Henri Lebesgue , although according to the Bourbaki group they were first introduced by Frigyes Riesz . spaces form an important class of Banach spaces in functional analysis, and of topological vector spaces. Because of their key role in the mathematical analysis of measure and probability spaces, Lebesgue spaces are used also in the theoretical discussion of problems in physics, statistics, economics, finance, engineering, and other disciplines. Preliminaries The -norm in finite dimensions The Euclidean length of a vector in the -dimensional real vector space is given by the Euclidean norm: The Euclidean distance between two points and is the length of the straight line between the two points. In many situations, the Euclidean distance is appropriate for capturing the actual distances in a given space. In contrast, consider taxi drivers in a grid street plan who should measure distance not in terms of the length of the straight line to their destination, but in terms of the rectilinear distance, which takes into account that streets are either orthogonal or parallel to each other. The class of -norms generalizes these two examples and has an abundance of applications in many parts of mathematics, physics, and computer science. For a real number the -norm or -norm of is defined by The absolute value bars can be dropped when is a rational number with an even numerator in its reduced form, and is drawn from the set of real numbers, or one of its subsets. The Euclidean norm from above falls into this class and is the -norm, and the -norm is the norm that corresponds to the rectilinear distance. The -norm or maximum norm (or uniform norm) is the limit of the -norms for , given by: For all the -norms and maximum norm satisfy the properties of a "length function" (or norm), that is: only the zero vector has zero length, the length of the vector is positive homogeneous with respect to multiplication by a scalar (positive homogeneity), and the length of the sum of two vectors is no larger than the sum of lengths of the vectors (triangle inequality). Abstractly speaking, this means that together with the -norm is a normed vector space. Moreover, it turns out that this space is complete, thus making it a Banach space. Relations between -norms The grid distance or rectilinear distance (sometimes called the "Manhattan distance") between two points is never shorter than the length of the line segment between them (the Euclidean or "as the crow flies" distance). Formally, this means that the Euclidean norm of any vector is bounded by its 1-norm: This fact generalizes to -norms in that the -norm of any given vector does not grow with : For the opposite direction, the following relation between the -norm and the -norm is known: This inequality depends on the dimension of the underlying vector space and follows directly from the Cauchy–Schwarz inequality. In general, for vectors in where This is a consequence of Hölder's inequality. When In for the formula defines an absolutely homogeneous function for however, the resulting function does not define a norm, because it is not subadditive. On the other hand, the formula defines a subadditive function at the cost of losing absolute homogeneity. It does define an F-norm, though, which is homogeneous of degree Hence, the function defines a metric. The metric space is denoted by Although the -unit ball around the origin in this metric is "concave", the topology defined on by the metric is the usual vector space topology of hence is a locally convex topological vector space. Beyond this qualitative statement, a quantitative way to measure the lack of convexity of is to denote by the smallest constant such that the scalar multiple of the -unit ball contains the convex hull of which is equal to The fact that for fixed we have shows that the infinite-dimensional sequence space defined below, is no longer locally convex. When There is one norm and another function called the "norm" (with quotation marks). The mathematical definition of the norm was established by Banach's Theory of Linear Operations. The space of sequences has a complete metric topology provided by the F-norm on the product metric: The -normed space is studied in functional analysis, probability theory, and harmonic analysis. Another function was called the "norm" by David Donoho—whose quotation marks warn that this function is not a proper norm—is the number of non-zero entries of the vector Many authors abuse terminology by omitting the quotation marks. Defining the zero "norm" of is equal to This is not a norm because it is not homogeneous. For example, scaling the vector by a positive constant does not change the "norm". Despite these defects as a mathematical norm, the non-zero counting "norm" has uses in scientific computing, information theory, and statistics–notably in compressed sensing in signal processing and computational harmonic analysis. Despite not being a norm, the associated metric, known as Hamming distance, is a valid distance, since homogeneity is not required for distances. spaces and sequence spaces The -norm can be extended to vectors that have an infinite number of components (sequences), which yields the space This contains as special cases: the space of sequences whose series are absolutely convergent, the space of square-summable sequences, which is a Hilbert space, and the space of bounded sequences. The space of sequences has a natural vector space structure by applying scalar addition and multiplication. Explicitly, the vector sum and the scalar action for infinite sequences of real (or complex) numbers are given by: Define the -norm: Here, a complication arises, namely that the series on the right is not always convergent, so for example, the sequence made up of only ones, will have an infinite -norm for The space is then defined as the set of all infinite sequences of real (or complex) numbers such that the -norm is finite. One can check that as increases, the set grows larger. For example, the sequence is not in but it is in for as the series diverges for (the harmonic series), but is convergent for One also defines the -norm using the supremum: and the corresponding space of all bounded sequences. It turns out that if the right-hand side is finite, or the left-hand side is infinite. Thus, we will consider spaces for The -norm thus defined on is indeed a norm, and together with this norm is a Banach space. General ℓp-space In complete analogy to the preceding definition one can define the space over a general index set (and ) as where convergence on the right means that only countably many summands are nonzero (see also Unconditional convergence). With the norm the space becomes a Banach space. In the case where is finite with elements, this construction yields with the -norm defined above. If is countably infinite, this is exactly the sequence space defined above. For uncountable sets this is a non-separable Banach space which can be seen as the locally convex direct limit of -sequence spaces. For the -norm is even induced by a canonical inner product called the , which means that holds for all vectors This inner product can expressed in terms of the norm by using the polarization identity. On it can be defined by Now consider the case Define where for all The index set can be turned into a measure space by giving it the discrete σ-algebra and the counting measure. Then the space is just a special case of the more general -space (defined below). Lp spaces and Lebesgue integrals An space may be defined as a space of measurable functions for which the -th power of the absolute value is Lebesgue integrable, where functions which agree almost everywhere are identified. More generally, let be a measure space and When , consider the set of all measurable functions from to or whose absolute value raised to the -th power has a finite integral, or in symbols: To define the set for recall that two functions and defined on are said to be , written , if the set is measurable and has measure zero. Similarly, a measurable function (and its absolute value) is (or ) by a real number written , if the (necessarily) measurable set has measure zero. The space is the set of all measurable functions that are bounded almost everywhere (by some real ) and is defined as the infimum of these bounds: When then this is the same as the essential supremum of the absolute value of : For example, if is a measurable function that is equal to almost everywhere then for every and thus for all For every positive the value under of a measurable function and its absolute value are always the same (that is, for all ) and so a measurable function belongs to if and only if its absolute value does. Because of this, many formulas involving -norms are stated only for non-negative real-valued functions. Consider for example the identity which holds whenever is measurable, is real, and (here when ). The non-negativity requirement can be removed by substituting in for which gives Note in particular that when is finite then the formula relates the -norm to the -norm. Seminormed space of -th power integrable functions Each set of functions forms a vector space when addition and scalar multiplication are defined pointwise. That the sum of two -th power integrable functions and is again -th power integrable follows from although it is also a consequence of Minkowski's inequality which establishes that satisfies the triangle inequality for (the triangle inequality does not hold for ). That is closed under scalar multiplication is due to being absolutely homogeneous, which means that for every scalar and every function Absolute homogeneity, the triangle inequality, and non-negativity are the defining properties of a seminorm. Thus is a seminorm and the set of -th power integrable functions together with the function defines a seminormed vector space. In general, the seminorm is not a norm because there might exist measurable functions that satisfy but are not equal to ( is a norm if and only if no such exists). Zero sets of -seminorms If is measurable and equals a.e. then for all positive On the other hand, if is a measurable function for which there exists some such that then almost everywhere. When is finite then this follows from the case and the formula mentioned above. Thus if is positive and is any measurable function, then if and only if almost everywhere. Since the right hand side ( a.e.) does not mention it follows that all have the same zero set (it does not depend on ). So denote this common set by This set is a vector subspace of for every positive Quotient vector space Like every seminorm, the seminorm induces a norm (defined shortly) on the canonical quotient vector space of by its vector subspace This normed quotient space is called and it is the subject of this article. We begin by defining the quotient vector space. Given any the coset consists of all measurable functions that are equal to almost everywhere. The set of all cosets, typically denoted by forms a vector space with origin when vector addition and scalar multiplication are defined by and This particular quotient vector space will be denoted by Two cosets are equal if and only if (or equivalently, ), which happens if and only if almost everywhere; if this is the case then and are identified in the quotient space. Hence, strictly speaking consists of equivalence classes of functions. The -norm on the quotient vector space Given any the value of the seminorm on the coset is constant and equal to denote this unique value by so that: This assignment defines a map, which will also be denoted by on the quotient vector space This map is a norm on called the . The value of a coset is independent of the particular function that was chosen to represent the coset, meaning that if is any coset then for every (since for every ). The Lebesgue space The normed vector space is called or the of -th power integrable functions and it is a Banach space for every (meaning that it is a complete metric space, a result that is sometimes called the [[Riesz–Fischer theorem#Completeness of Lp, 0 < p ≤ ∞|Riesz–Fischer theorem]]). When the underlying measure space is understood then is often abbreviated or even just Depending on the author, the subscript notation might denote either or If the seminorm on happens to be a norm (which happens if and only if ) then the normed space will be linearly isometrically isomorphic to the normed quotient space via the canonical map (since ); in other words, they will be, up to a linear isometry, the same normed space and so they may both be called " space". The above definitions generalize to Bochner spaces. In general, this process cannot be reversed: there is no consistent way to define a "canonical" representative of each coset of in For however, there is a theory of lifts enabling such recovery. Special cases For the spaces are a special case of spaces; when are the natural numbers and is the counting measure. More generally, if one considers any set with the counting measure, the resulting space is denoted For example, is the space of all sequences indexed by the integers, and when defining the -norm on such a space, one sums over all the integers. The space where is the set with elements, is with its -norm as defined above. Similar to spaces, is the only Hilbert space among spaces. In the complex case, the inner product on is defined by Functions in are sometimes called square-integrable functions, quadratically integrable functions or square-summable functions, but sometimes these terms are reserved for functions that are square-integrable in some other sense, such as in the sense of a Riemann integral . As any Hilbert space, every space is linearly isometric to a suitable where the cardinality of the set is the cardinality of an arbitrary basis for this particular If we use complex-valued functions, the space is a commutative C*-algebra with pointwise multiplication and conjugation. For many measure spaces, including all sigma-finite ones, it is in fact a commutative von Neumann algebra. An element of defines a bounded operator on any space by multiplication. When If then can be defined as above, that is: In this case, however, the -norm does not satisfy the triangle inequality and defines only a quasi-norm. The inequality valid for implies that and so the function is a metric on The resulting metric space is complete. In this setting satisfies a reverse Minkowski inequality, that is for This result may be used to prove Clarkson's inequalities, which are in turn used to establish the uniform convexity of the spaces for . The space for is an F-space: it admits a complete translation-invariant metric with respect to which the vector space operations are continuous. It is the prototypical example of an F-space that, for most reasonable measure spaces, is not locally convex: in or every open convex set containing the function is unbounded for the -quasi-norm; therefore, the vector does not possess a fundamental system of convex neighborhoods. Specifically, this is true if the measure space contains an infinite family of disjoint measurable sets of finite positive measure. The only nonempty convex open set in is the entire space. Consequently, there are no nonzero continuous linear functionals on the continuous dual space is the zero space. In the case of the counting measure on the natural numbers (i.e. ), the bounded linear functionals on are exactly those that are bounded on , i.e., those given by sequences in Although does contain non-trivial convex open sets, it fails to have enough of them to give a base for the topology. Having no linear functionals is highly undesirable for the purposes of doing analysis. In case of the Lebesgue measure on rather than work with for it is common to work with the Hardy space whenever possible, as this has quite a few linear functionals: enough to distinguish points from one another. However, the Hahn–Banach theorem still fails in for . Properties Hölder's inequality Suppose satisfy . If and then and This inequality, called Hölder's inequality, is in some sense optimal since if and is a measurable function such that where the supremum is taken over the closed unit ball of then and Generalized Minkowski inequality Minkowski inequality, which states that satisfies the triangle inequality, can be generalized: If the measurable function is non-negative (where and are measure spaces) then for all Atomic decomposition If then every non-negative has an , meaning that there exist a sequence of non-negative real numbers and a sequence of non-negative functions called , whose supports are pairwise disjoint sets of measure such that and for every integer and and where moreover, the sequence of functions depends only on (it is independent of ). These inequalities guarantee that for all integers while the supports of being pairwise disjoint implies An atomic decomposition can be explicitly given by first defining for every integer and then letting where denotes the measure of the set and denotes the indicator function of the set The sequence is decreasing and converges to as Consequently, if then and so that is identically equal to (in particular, the division by causes no issues). The complementary cumulative distribution function of that was used to define the also appears in the definition of the weak -norm (given below) and can be used to express the -norm (for ) of as the integral where the integration is with respect to the usual Lebesgue measure on Dual spaces The dual space of for has a natural isomorphism with where is such that . This isomorphism associates with the functional defined by for every is a well defined continuous linear mapping which is an isometry by the extremal case of Hölder's inequality. If is a -finite measure space one can use the Radon–Nikodym theorem to show that any can be expressed this way, i.e., is an isometric isomorphism of Banach spaces. Hence, it is usual to say simply that is the continuous dual space of For the space is reflexive. Let be as above and let be the corresponding linear isometry. Consider the map from to obtained by composing with the transpose (or adjoint) of the inverse of This map coincides with the canonical embedding of into its bidual. Moreover, the map is onto, as composition of two onto isometries, and this proves reflexivity. If the measure on is sigma-finite, then the dual of is isometrically isomorphic to (more precisely, the map corresponding to is an isometry from onto The dual of is subtler. Elements of can be identified with bounded signed finitely additive measures on that are absolutely continuous with respect to See ba space for more details. If we assume the axiom of choice, this space is much bigger than except in some trivial cases. However, Saharon Shelah proved that there are relatively consistent extensions of Zermelo–Fraenkel set theory (ZF + DC + "Every subset of the real numbers has the Baire property") in which the dual of is Embeddings Colloquially, if then contains functions that are more locally singular, while elements of can be more spread out. Consider the Lebesgue measure on the half line A continuous function in might blow up near but must decay sufficiently fast toward infinity. On the other hand, continuous functions in need not decay at all but no blow-up is allowed. More formally: If : if and only if does not contain sets of finite but arbitrarily large measure (e.g. any finite measure). If : if and only if does not contain sets of non-zero but arbitrarily small measure (e.g. the counting measure). Neither condition holds for the Lebesgue measure on the real line while both conditions holds for the counting measure on any finite set. As a consequence of the closed graph theorem, the embedding is continuous, i.e., the identity operator is a bounded linear map from to in the first case and to in the second. Indeed, if the domain has finite measure, one can make the following explicit calculation using Hölder's inequality leading to The constant appearing in the above inequality is optimal, in the sense that the operator norm of the identity is precisely the case of equality being achieved exactly when -almost-everywhere. Dense subspaces Let and be a measure space and consider an integrable simple function on given by where are scalars, has finite measure and is the indicator function of the set for By construction of the integral, the vector space of integrable simple functions is dense in More can be said when is a normal topological space and its Borel –algebra. Suppose is an open set with Then for every Borel set contained in there exist a closed set and an open set such that for every . Subsequently, there exists a Urysohn function on that is on and on with If can be covered by an increasing sequence of open sets that have finite measure, then the space of –integrable continuous functions is dense in More precisely, one can use bounded continuous functions that vanish outside one of the open sets This applies in particular when and when is the Lebesgue measure. For example, the space of continuous and compactly supported functions as well as the space of integrable step functions are dense in . Closed subspaces If is any positive real number, is a probability measure on a measurable space (so that ), and is a vector subspace, then is a closed subspace of if and only if is finite-dimensional ( was chosen independent of ). In this theorem, which is due to Alexander Grothendieck, it is crucial that the vector space be a subset of since it is possible to construct an infinite-dimensional closed vector subspace of (which is even a subset of ), where is Lebesgue measure on the unit circle and is the probability measure that results from dividing it by its mass Applications Statistics In statistics, measures of central tendency and statistical dispersion, such as the mean, median, and standard deviation, can be defined in terms of metrics, and measures of central tendency can be characterized as solutions to variational problems. In penalized regression, "L1 penalty" and "L2 penalty" refer to penalizing either the norm of a solution's vector of parameter values (i.e. the sum of its absolute values), or its squared norm (its Euclidean length). Techniques which use an L1 penalty, like LASSO, encourage sparse solutions (where the many parameters are zero). Elastic net regularization uses a penalty term that is a combination of the norm and the squared norm of the parameter vector. Hausdorff–Young inequality The Fourier transform for the real line (or, for periodic functions, see Fourier series), maps to (or to ) respectively, where and This is a consequence of the Riesz–Thorin interpolation theorem, and is made precise with the Hausdorff–Young inequality. By contrast, if the Fourier transform does not map into Hilbert spaces Hilbert spaces are central to many applications, from quantum mechanics to stochastic calculus. The spaces and are both Hilbert spaces. In fact, by choosing a Hilbert basis i.e., a maximal orthonormal subset of or any Hilbert space, one sees that every Hilbert space is isometrically isomorphic to (same as above), i.e., a Hilbert space of type Generalizations and extensions Weak Let be a measure space, and a measurable function with real or complex values on The distribution function of is defined for by If is in for some with then by Markov's inequality, A function is said to be in the space weak , or if there is a constant such that, for all The best constant for this inequality is the -norm of and is denoted by The weak coincide with the Lorentz spaces so this notation is also used to denote them. The -norm is not a true norm, since the triangle inequality fails to hold. Nevertheless, for in and in particular In fact, one has and raising to power and taking the supremum in one has Under the convention that two functions are equal if they are equal almost everywhere, then the spaces are complete . For any the expression is comparable to the -norm. Further in the case this expression defines a norm if Hence for the weak spaces are Banach spaces . A major result that uses the -spaces is the Marcinkiewicz interpolation theorem, which has broad applications to harmonic analysis and the study of singular integrals. Weighted spaces As before, consider a measure space Let be a measurable function. The -weighted space is defined as where means the measure defined by or, in terms of the Radon–Nikodym derivative, the norm for is explicitly As -spaces, the weighted spaces have nothing special, since is equal to But they are the natural framework for several results in harmonic analysis ; they appear for example in the Muckenhoupt theorem: for the classical Hilbert transform is defined on where denotes the unit circle and the Lebesgue measure; the (nonlinear) Hardy–Littlewood maximal operator is bounded on Muckenhoupt's theorem describes weights such that the Hilbert transform remains bounded on and the maximal operator on spaces on manifolds One may also define spaces on a manifold, called the intrinsic spaces of the manifold, using densities. Vector-valued spaces Given a measure space and a locally convex space (here assumed to be complete), it is possible to define spaces of -integrable -valued functions on in a number of ways. One way is to define the spaces of Bochner integrable and Pettis integrable functions, and then endow them with locally convex TVS-topologies that are (each in their own way) a natural generalization of the usual topology. Another way involves topological tensor products of with Element of the vector space are finite sums of simple tensors where each simple tensor may be identified with the function that sends This tensor product is then endowed with a locally convex topology that turns it into a topological tensor product, the most common of which are the projective tensor product, denoted by and the injective tensor product, denoted by In general, neither of these space are complete so their completions are constructed, which are respectively denoted by and (this is analogous to how the space of scalar-valued simple functions on when seminormed by any is not complete so a completion is constructed which, after being quotiented by is isometrically isomorphic to the Banach space ). Alexander Grothendieck showed that when is a nuclear space (a concept he introduced), then these two constructions are, respectively, canonically TVS-isomorphic with the spaces of Bochner and Pettis integral functions mentioned earlier; in short, they are indistinguishable. space of measurable functions The vector space of (equivalence classes of) measurable functions on is denoted . By definition, it contains all the and is equipped with the topology of convergence in measure. When is a probability measure (i.e., ), this mode of convergence is named convergence in probability. The space is always a topological abelian group but is only a topological vector space if This is because scalar multiplication is continuous if and only if If is -finite then the weaker topology of local convergence in measure is an F-space, i.e. a completely metrizable topological vector space. Moreover, this topology is isometric to global convergence in measure for a suitable choice of probability measure The description is easier when is finite. If is a finite measure on the function admits for the convergence in measure the following fundamental system of neighborhoods The topology can be defined by any metric of the form where is bounded continuous concave and non-decreasing on with and when (for example, Such a metric is called Lévy-metric for Under this metric the space is complete. However, as mentioned above, scalar multiplication is continuous with respect to this metric only if . To see this, consider the Lebesgue measurable function defined by . Then clearly . The space is in general not locally bounded, and not locally convex. For the infinite Lebesgue measure on the definition of the fundamental system of neighborhoods could be modified as follows The resulting space , with the topology of local convergence in measure, is isomorphic to the space for any positive –integrable density See also Notes References . . . . . . External links Proof that Lp spaces are complete The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the significance of Lp spaces in mathematics and other disciplines according to the text? A. They are only useful in abstract mathematics. B. They are crucial for mathematical analysis and have applications in physics, statistics, and finance. C. They are primarily concerned with the geometric properties of shapes. D. They are only relevant in the study of finite-dimensional vector spaces. Answer:
B. They are crucial for mathematical analysis and have applications in physics, statistics, and finance.
Relavent Documents: Document 0::: Tesamorelin (INN; trade name Egrifta SV) is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated lipodystrophy, approved initially in 2010. It is produced and developed by Theratechnologies, Inc. of Canada. The drug is a synthetic peptide consisting of all 44 amino acids of human GHRH with the addition of a trans-3-hexenoic acid group. Mechanism of action Tesamorelin is the N-terminally modified compound based on 44 amino acids sequence of human GHRH. This modified synthetic form is more potent and stable than the natural peptide. It is also more resistant to cleavage by the dipeptidyl aminopeptidase than human GHRH. It stimulates the synthesis and release of endogenous GH, with an increase in level of insulin-like growth factor (IGF-1). The released GH then binds with the receptors present on various body organs and regulates the body composition. This regulation is mainly because of the combination of anabolic and lipolytic mechanisms. However, it has been found that the main mechanisms by which Tesamorelin reduces body fat mass are lipolysis followed by reduction in triglycerides level. Contraindication Tesamorelin therapy may cause glucose intolerance and increase the risk of type 2-diabetes, so it is contraindicated in pregnancy. It is also contraindicated in pregnancy (category X) because it may cause harm to fetus. It is also contraindicated in patients affected by hypothalamic-pituitary axis disruption due to pituitary gland tumor, head irradiation and hypopituitarism. Adverse effects Injection site erythema, peripheral edema, injection site pruritus and diarrhea. Document 1::: A demining robot is a robotic land vehicle that is designed for detecting the exact location of land mines and clearing them. Demining by conventional methods can be costly and dangerous for people. Environments that are dull or dirty, or otherwise dangerous to humans, may be well-suited for the use of demining robots. Models Uran-6 Uran-6 is a demining robot model used by Russian Federation in Syria and Ukraine. The Uran-6 is a short-range and remotely piloted robot. Limitations of this robot include the need for human operators to be within a few hundred feet. MV-4 Dok-Ing MV-4 Dok-Ing is a demining robot model used by Republic of Croatia. See also Lawnmower robot Vacuum cleaner robot References Document 2::: Melt is the working material in the steelmaking process, in making glass, and when forming thermoplastics. In thermoplastics, melt is the plastic in its forming temperature, which can vary depending on how it is being used. For steelmaking, it refers to steel in liquid form. See also Wax melter Crucible References Notes Bibliography . . Document 3::: This is a list of municipalities in Finland. There are a total of 308 municipalities, of which 114 have both a Finnish and a Swedish name. These municipalities are listed by the name in the local majority language, with the name in the other national language provided in parentheses. Finnish is the majority language in 99 of these 114 municipalities, while Swedish is the majority language in the remaining 15 municipalities. The four municipalities that are wholly or partly within the Sami native region have their names also given in the local Sami languages. {{aligned table | cols=4 | class=wikitable sortable | row1header=y | col3align=center | col4align=right | Municipality | Administrativecenter |Locationon map|Land area(km2) </th> Population() Density(/km2) | ||| | (Swedish: ) | | | | | | | | | Alavieska | | | | Alavus | | | | | | | | Askola | | | | Aura | | | | | | | | | | | | Enonkoski | | | | Hetta | | | | | | | | Eura | | | | Eurajoki | | | | | | | | | | | | Forssa | | | | | | | | Geta (Vestergeta) | | | | | | | | Haapavesi | | | | Hailuoto | | | | Halsua | | | | Hamina | | | | Hammarland (Kattby) | | | | Hankasalmi | | | | Hanko | | | | Harjavalta | | | | Hartola | | | | Parola | | | | | | | | Heinola | | | | Heinävesi | | | | Helsinki | | | | Hirvensalmi | | | | | | | | | | | | Humppila | | | | Hyrynsalmi | | | | | | | | | | | | | | | | Ii (Iin Hamina) | | | | Iisalmi | | | | | | | | Ikaalinen | | | | Ilmajoki | | | | Ilomantsi | | | | Mansikkala | | | | | | | | | | | | Isojoki | | | | | | | | Jakobstad | | | | | | | | Joensuu | | | | Jokioinen | | | | | | | | Joroinen | | | | Joutsa | | | | Juuka | | | | | | | | Juva | | | | | | | | | | | | | | | | | | | | Kaarina | | | | Kaavi | | | | Kajaani | | | | Kalajoki | | | | The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What was the primary goal of the Brotherhood in "The Invisible Empire"? A. To create a new world religion B. To gain control over the entire world C. To protect the innocent from evil D. To develop advanced technology for peace Answer:
B. To gain control over the entire world
Relavent Documents: Document 0::: Majorana 1 is a hardware device developed by Microsoft, with potential applications to quantum computing. It is the first device produced by Microsoft intended for use in quantum computing. It is an indium arsenide-aluminium hybrid device that admits superconductivity at low temperatures. Microsoft claims that it shows some signals of hosting boundary Majorana zero modes. The device can fit eight qubits. Majorana zero modes, if confirmed, could have potential application to making topological qubits, and eventually a large-scale topological quantum computers. In its February 2025 announcement, Microsoft claimed that the Majorana 1 represents progress in its long-running project to create a quantum computer based on topological qubits. The announcement has generated both excitement and skepticism within the scientific community, in the absence of definitive public evidence that the Majorana 1 device exhibits Majorana zero modes. Background Quantum computing research has historically faced challenges in achieving qubit stability and scalability. Traditional qubits, such as those based on superconducting circuits or trapped ions, are highly susceptible to noise and decoherence, which can introduce errors in computations. To overcome these limitations, researchers have been exploring various approaches to building more robust and fault-tolerant quantum computers. Topological qubits, first theorized in 1997 by Alexei Kitaev and Michael Freedman, offer a promising solution by encoding quantum information in a way that is inherently protected from environmental disturbances. This protection stems from the topological properties of the system, which are resistant to local perturbations. Microsoft's approach, based on Majorana fermions in semiconductor-superconductor heterostructures, is one of several efforts to realize topological quantum computing. Controversy Microsoft's quantum hardware has been the subject of controversy since its high-profile retracted articl Document 1::: Plants may reproduce sexually or asexually. Sexual reproduction produces offspring by the fusion of gametes, resulting in offspring genetically different from either parent. Vegetative reproduction produces new individuals without the fusion of gametes, resulting in clonal plants that are genetically identical to the parent plant and each other, unless mutations occur. In asexual reproduction, only one parent is involved. Asexual reproduction Asexual reproduction does not involve the production and fusion of male and female gametes. Asexual reproduction may occur through budding, fragmentation, spore formation, regeneration and vegetative propagation. Asexual reproduction is a type of reproduction where the offspring comes from one parent only, thus inheriting the characteristics of the parent. Asexual reproduction in plants occurs in two fundamental forms, vegetative reproduction and agamospermy. Vegetative reproduction involves a vegetative piece of the original plant producing new individuals by budding, tillering, etc. and is distinguished from apomixis, which is a replacement of sexual reproduction, and in some cases involves seeds. Apomixis occurs in many plant species such as dandelions (Taraxacum species) and also in some non-plant organisms. For apomixis and similar processes in non-plant organisms, see parthenogenesis. Natural vegetative reproduction is a process mostly found in perennial plants, and typically involves structural modifications of the stem or roots and in a few species leaves. Most plant species that employ vegetative reproduction do so as a means to perennialize the plants, allowing them to survive from one season to the next and often facilitating their expansion in size. A plant that persists in a location through vegetative reproduction of individuals gives rise to a clonal colony. A single ramet, or apparent individual, of a clonal colony is genetically identical to all others in the same colony. The distance that a plant can move during vegetative reproduction is limited, though some plants can produce ramets from branching rhizomes or stolons that cover a wide area, often in only a few growing seasons. In a sense, this process is not one of reproduction but one of survival and expansion of biomass of the individual. When an individual organism increases in size via cell multiplication and remains intact, the process is called vegetative growth. However, in vegetative reproduction, the new plants that result are new individuals in almost every respect except genetic. A major disadvantage of vegetative reproduction is the transmission of pathogens from parent to offspring. It is uncommon for pathogens to be transmitted from the plant to its seeds (in sexual reproduction or in apomixis), though there are occasions when it occurs. Seeds generated by apomixis are a means of asexual reproduction, involving the formation and dispersal of seeds that do not originate from the fertilization of the embryos. Hawkweeds (Hieracium), dandelions (Taraxacum), some species of Citrus and Kentucky blue grass (Poa pratensis) all use this form of asexual reproduction. Pseudogamy occurs in some plants that have apomictic seeds, where pollination is often needed to initiate embryo growth, though the pollen contributes no genetic material to the developing offspring. Other forms of apomixis occur in plants also, including the generation of a plantlet in replacement of a seed or the generation of bulbils instead of flowers, where new cloned individuals are produced. Structures A rhizome is a modified underground stem serving as an organ of vegetative reproduction; the growing tips of the rhizome can separate as new plants, e.g., polypody, iris, couch grass and nettles. Prostrate aerial stems, called runners or stolons, are important vegetative reproduction organs in some species, such as the strawberry, numerous grasses, and some ferns. Adventitious buds form on roots near the ground surface, on damaged stems (as on the stumps of cut trees), or on old roots. These develop into above-ground stems and leaves. A form of budding called suckering is the reproduction or regeneration of a plant by shoots that arise from an existing root system. Species that characteristically produce suckers include elm (Ulmus) and many members of the rose family such as Rosa, Kerria and Rubus. Bulbous plants such as onion (Allium cepa), hyacinths, narcissi and tulips reproduce vegetatively by dividing their underground bulbs into more bulbs. Other plants like potatoes (Solanum tuberosum) and dahlias reproduce vegetatively from underground tubers. Gladioli and crocuses reproduce vegetatively in a similar way with corms. Gemmae are single cells or masses of cells that detach from plants to form new clonal individuals. These are common in Liverworts and mosses and in the gametophyte generation of some filmy fern. They are also present in some Club mosses such as Huperzia lucidula . They are also found in some higher plants such as species of Drosera. Usage The most common form of plant reproduction used by people is seeds, but a number of asexual methods are used which are usually enhancements of natural processes, including: cutting, grafting, budding, layering, division, sectioning of rhizomes, roots, tubers, bulbs, stolons, tillers, etc., and artificial propagation by laboratory tissue cloning. Asexual methods are most often used to propagate cultivars with individual desirable characteristics that do not come true from seed. Fruit tree propagation is frequently performed by budding or grafting desirable cultivars (clones), onto rootstocks that are also clones, propagated by stooling. In horticulture, a cutting is a branch that has been cut off from a mother plant below an internode and then rooted, often with the help of a rooting liquid or powder containing hormones. When a full root has formed and leaves begin to sprout anew, the clone is a self-sufficient plant, genetically identical. Examples include cuttings from the stems of blackberries (Rubus occidentalis), African violets (Saintpaulia), verbenas (Verbena) to produce new plants. A related use of cuttings is grafting, where a stem or bud is joined onto a different stem. Nurseries offer for sale trees with grafted stems that can produce four or more varieties of related fruits, including apples. The most common usage of grafting is the propagation of cultivars onto already rooted plants, sometimes the rootstock is used to dwarf the plants or protect them from root damaging pathogens. Since vegetatively propagated plants are clones, they are important tools in plant research. When a clone is grown in various conditions, differences in growth can be ascribed to environmental effects instead of genetic differences. Sexual reproduction Sexual reproduction involves two fundamental processes: meiosis, which rearranges the genes and reduces the number of chromosomes, and fertilization, which restores the chromosome to a complete diploid number. In between these two processes, different types of plants and algae vary, but many of them, including all land plants, undergo alternation of generations, with two different multicellular structures (phases), a gametophyte and a sporophyte. The evolutionary origin and adaptive significance of sexual reproduction are discussed in the pages Evolution of sexual reproduction and Origin and function of meiosis. The gametophyte is the multicellular structure (plant) that is haploid, containing a single set of chromosomes in each cell. The gametophyte produces male or female gametes (or both), by a process of cell division, called mitosis. In vascular plants with separate gametophytes, female gametophytes are known as mega gametophytes (mega=large, they produce the large egg cells) and the male gametophytes are called micro gametophytes (micro=small, they produce the small sperm cells). The fusion of male and female gametes (fertilization) produces a diploid zygote, which develops by mitotic cell divisions into a multicellular sporophyte. The mature sporophyte produces spores by meiosis, sometimes referred to as reduction division because the chromosome pairs are separated once again to form single sets. In mosses and liverworts, the gametophyte is relatively large, and the sporophyte is a much smaller structure that is never separated from the gametophyte. In ferns, gymnosperms, and flowering plants (angiosperms), the gametophytes are relatively small and the sporophyte is much larger. In gymnosperms and flowering plants the megagametophyte is contained within the ovule (that may develop into a seed) and the microgametophyte is contained within a pollen grain. History of sexual reproduction of plants Unlike animals, plants are immobile, and cannot seek out sexual partners for reproduction. In the evolution of early plants, abiotic means, including water and much later, wind, transported sperm for reproduction. The first plants were aquatic, as described in the page Evolutionary history of plants, and released sperm freely into the water to be carried with the currents. Primitive land plants such as liverworts and mosses had motile sperm that swam in a thin film of water or were splashed in water droplets from the male reproduction organs onto the female organs. As taller and more complex plants evolved, modifications in the alternation of generations evolved. In the Paleozoic era progymnosperms reproduced by using spores dispersed on the wind. The seed plants including seed ferns, conifers and cordaites, which were all gymnosperms, evolved about 350 million years ago. They had pollen grains that contained the male gametes for protection of the sperm during the process of transfer from the male to female parts. It is believed that insects fed on the pollen, and plants thus evolved to use insects to actively carry pollen from one plant to the next. Seed producing plants, which include the angiosperms and the gymnosperms, have a heteromorphic alternation of generations with large sporophytes containing much-reduced gametophytes. Angiosperms have distinctive reproductive organs called flowers, with carpels, and the female gametophyte is greatly reduced to a female embryo sac, with as few as eight cells. Each pollen grains contains a greatly reduced male gametophyte consisting of three or four cells. The sperm of seed plants are non-motile, except for two older groups of plants, the Cycadophyta and the Ginkgophyta, which have flagella. Flowering plants Flowering plants, the dominant plant group, reproduce both by sexual and asexual means. Their distinguishing feature is that their reproductive organs are contained in flowers. Sexual reproduction in flowering plants involves the production of separate male and female gametophytes that produce gametes. The anther produces pollen grains that contain male gametophytes. The pollen grains attach to the stigma on top of a carpel, in which the female gametophytes (inside ovules) are located. Plants may either self-pollinate or cross-pollinate. The transfer of pollen (the male gametophytes) to the female stigmas occurs is called pollination. After pollination occurs, the pollen grain germinates to form a pollen tube that grows through the carpel's style and transports male nuclei to the ovule to fertilize the egg cell and central cell within the female gametophyte in a process termed double fertilization. The resulting zygote develops into an embryo, while the triploid endosperm (one sperm cell plus a binucleate female cell) and female tissues of the ovule give rise to the surrounding tissues in the developing seed. The fertilized ovules develop into seeds within a fruit formed from the ovary. When the seeds are ripe they may be dispersed together with the fruit or freed from it by various means to germinate and grow into the next generation. Pollination Plants that use insects or other animals to move pollen from one flower to the next have developed greatly modified flower parts to attract pollinators and to facilitate the movement of pollen from one flower to the insect and from the insect to the next flower. Flowers of wind-pollinated plants tend to lack petals and or sepals; typically large amounts of pollen are produced and pollination often occurs early in the growing season before leaves can interfere with the dispersal of the pollen. Many trees and all grasses and sedges are wind-pollinated. Plants have a number of different means to attract pollinators including color, scent, heat, nectar glands, edible pollen and flower shape. Along with modifications involving the above structures two other conditions play a very important role in the sexual reproduction of flowering plants, the first is the timing of flowering and the other is the size or number of flowers produced. Often plant species have a few large, very showy flowers while others produce many small flowers, often flowers are collected together into large inflorescences to maximize their visual effect, becoming more noticeable to passing pollinators. Flowers are attraction strategies and sexual expressions are functional strategies used to produce the next generation of plants, with pollinators and plants having co-evolved, often to some extraordinary degrees, very often rendering mutual benefit. The largest family of flowering plants is the orchids (Orchidaceae), estimated by some specialists to include up to 35,000 species, which often have highly specialized flowers that attract particular insects for pollination. The stamens are modified to produce pollen in clusters called pollinia, which become attached to insects that crawl into the flower. The flower shapes may force insects to pass by the pollen, which is "glued" to the insect. Some orchids are even more highly specialized, with flower shapes that mimic the shape of insects to attract them to attempt to 'mate' with the flowers, a few even have scents that mimic insect pheromones. Another large group of flowering plants is the Asteraceae or sunflower family with close to 22,000 species, which also have highly modified inflorescences composed of many individual flowers called florets. Heads with florets of one sex, when the flowers are pistillate or functionally staminate or made up of all bisexual florets, are called homogamous and can include discoid and liguliflorous type heads. Some radiate heads may be homogamous too. Plants with heads that have florets of two or more sexual forms are called heterogamous and include radiate and disciform head forms. Ferns Ferns typically produce large diploids with stem, roots, and leaves. On fertile leaves sporangia are produced, grouped together in sori and often protected by an indusium. If the spores are deposited onto a suitable moist substrate they germinate to produce short, thin, free-living gametophytes called prothalli that are typically heart-shaped, small and green in color. The gametophytes produce both motile sperm in the antheridia and egg cells in separate archegonia. After rains or when dew deposits a film of water, the motile sperm are splashed away from the antheridia, which are normally produced on the top side of the thallus, and swim in the film of water to the antheridia where they fertilize the egg. To promote out crossing or cross-fertilization the sperm is released before the eggs are receptive of the sperm, making it more likely that the sperm will fertilize the eggs of the different thallus. A zygote is formed after fertilization, which grows into a new sporophytic plant. The condition of having separate sporophyte and gametophyte plants is called alternation of generations. Other plants with similar reproductive strategies include Psilotum, Lycopodium, Selaginella and Equisetum. Bryophytes The bryophytes, which include liverworts, hornworts and mosses, can reproduce both sexually and vegetatively. The life cycles of these plants start with haploid spores that grow into the dominant form, which is a multicellular haploid gametophyte, with thalloid or leaf-like structures that photosynthesize. The gametophyte is the most commonly known phase of the plant. Bryophytes are typically small plants that grow in moist locations and like ferns, have motile sperm which swim to the ovule using flagella and therefore need water to facilitate sexual reproduction. Bryophytes show considerable variation in their reproductive structures, and a basic outline is as follows: Haploid gametes are produced in antheridia and archegonia by mitosis. The sperm released from the antheridia respond to chemicals released by ripe archegonia and swim to them in a film of water and fertilize the egg cells, thus producing zygotes that are diploid. The zygote divides repeatedly by mitotic division and grows into a diploid sporophyte. The resulting multicellular diploid sporophyte produces spore capsules called sporangia. The spores are produced by meiosis, and when ripe, the capsules burst open to release the spores. In some species each gametophyte is one sex while other species may be monoicous, producing both antheridia and archegonia on the same gametophyte which is thus hermaphrodite. Algae Sexual reproduction in the multicellular facultatively sexual green alga Volvox carteri is induced by oxidative stress. A two-fold increase in cellular reactive oxygen species (associated with oxidative stress) activates the V. carteri genes needed for sexual reproduction. Exposure to antioxidants inhibits the induction of sex in V. carteri. It was proposed on the basis of these observations that sexual reproduction emerged in V. carteri evolution as an adaptive response to oxidative stress and the DNA damage induced by reactive oxygen species. Oxidative stress induced DNA damage may be repaired during the meiotic event associated with germination of the zygospore and the start of a new generation. Dispersal and offspring care One of the outcomes of plant reproduction is the generation of seeds, spores, and fruits that allow plants to move to new locations or new habitats. Plants do not have nervous systems or any will for their actions. Even so, scientists are able to observe mechanisms that help their offspring thrive as they grow. All organisms have mechanisms to increase survival in offspring. Offspring care is observed in the Mammillaria hernandezii, a small cactus found in Mexico. A cactus is a type of succulent, meaning it retains water when it is available for future droughts. M. hernandezii also stores a portion of its seeds in its stem, and releases the rest to grow. This can be advantageous for many reasons. By delaying the release of some of its seeds, the cactus can protect these from potential threats from insects, herbivores, or mold caused by micro-organisms. A study found that the presence of adequate water in the environment causes M. Hernandezii to release more seeds to allow for germination. The plant was able to perceive a water potential gradient in the surroundings, and act by giving its seeds a better chance in this preferable environment. This evolutionary strategy gives a better potential outcome for seed germination. External links Simple Video Tutorial on Reproduction in Plant Document 2::: Foraminoplasty is a type of endoscopic surgery used to operate on the spine. It is considered a minimally invasive surgery technique and its endoscopic laser is legally regulated. Although most patients have benefited from foraminoplasty, the National Institute for Health and Care Excellence does not fully support it due to it not completing its randomised controlled clinical trial. External links http://ijssurgery.com/10.14444/1026 https://www.nice.org.uk/guidance/ipg31/informationforpublic Document 3::: A voltage doubler is an electronic circuit which charges capacitors from the input voltage and switches these charges in such a way that, in the ideal case, exactly twice the voltage is produced at the output as at its input. The simplest of these circuits is a form of rectifier which take an AC voltage as input and outputs a doubled DC voltage. The switching elements are simple diodes and they are driven to switch state merely by the alternating voltage of the input. DC-to-DC voltage doublers cannot switch in this way and require a driving circuit to control the switching. They frequently also require a switching element that can be controlled directly, such as a transistor, rather than relying on the voltage across the switch as in the simple AC-to-DC case. Voltage doublers are a variety of voltage multiplier circuits. Many, but not all, voltage doubler circuits can be viewed as a single stage of a higher order multiplier: cascading identical stages together achieves a greater voltage multiplication. Voltage doubling rectifiers Villard circuit The Villard circuit, conceived by Paul Ulrich Villard, consists simply of a capacitor and a diode. While it has the great benefit of simplicity, its output has very poor ripple characteristics. Essentially, the circuit is a diode clamp circuit. The capacitor is charged on the negative half cycles to the peak AC voltage (Vpk). The output is the superposition of the input AC waveform and the steady DC of the capacitor. The effect of the circuit is to shift the DC value of the waveform. The negative peaks of the AC waveform are "clamped" to 0 V (actually −VF, the small forward bias voltage of the diode) by the diode, therefore the positive peaks of the output waveform are 2Vpk. The peak-to-peak ripple is an enormous 2Vpk and cannot be smoothed unless the circuit is effectively turned into one of the more sophisticated forms. This is the circuit (with diode reversed) used to supply the negative high voltage for the The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the main disadvantage of vegetative reproduction in plants? A. It requires two parents for offspring. B. It limits genetic diversity among offspring. C. It is not effective for perennial plants. D. It does not allow for the use of seeds. Answer:
B. It limits genetic diversity among offspring.
Relavent Documents: Document 0::: In organometallic chemistry, agostic interaction refers to the intramolecular interaction of a coordinatively-unsaturated transition metal with an appropriately situated C−H bond on one of its ligands. The interaction is the result of two electrons involved in the C−H bond interaction with an empty d-orbital of the transition metal, resulting in a three-center two-electron bond. It is a special case of a C–H sigma complex. Historically, agostic complexes were the first examples of C–H sigma complexes to be observed spectroscopically and crystallographically, due to intramolecular interactions being particularly favorable and more often leading to robust complexes. Many catalytic transformations involving oxidative addition and reductive elimination are proposed to proceed via intermediates featuring agostic interactions. Agostic interactions are observed throughout organometallic chemistry in alkyl, alkylidene, and polyenyl ligands. History The term agostic, derived from the Ancient Greek word for "to hold close to oneself", was coined by Maurice Brookhart and Malcolm Green, on the suggestion of the classicist Jasper Griffin, to describe this and many other interactions between a transition metal and a C−H bond. Often such agostic interactions involve alkyl or aryl groups that are held close to the metal center through an additional σ-bond. Short interactions between hydrocarbon substituents and coordinatively unsaturated metal complexes have been noted since the 1960s. For example, in tris(triphenylphosphine) ruthenium dichloride, a short interaction is observed between the ruthenium(II) center and a hydrogen atom on the ortho position of one of the nine phenyl rings. Complexes of borohydride are described as using the three-center two-electron bonding model. The nature of the interaction was foreshadowed in main group chemistry in the structural chemistry of trimethylaluminium. Characteristics of agostic bonds Agostic interactions are best demonstrated Document 1::: Street reclaiming is the process of converting, or otherwise returning streets to a stronger focus on non-car use — such as walking, cycling and active street life. It is advocated by many urban planners and urban economists, of widely varying political points of view. Its primary benefits are thought to be: Decreased automobile traffic with less noise pollution, fewer automobile accidents, reduced smog and air pollution Greater safety and access for pedestrians and cyclists Less frequent surface maintenance than car-driven roads Reduced summer temperatures due to less asphalt and more green spaces Increased pedestrian traffic which also increases social and commercial opportunities Increased gardening space for urban residents Better support for co-housing and infirm residents, e.g. suburban eco-villages built around former streets Campaigns An early example of street reclamation was the Stockholm carfree day in 1969. Some consider the best advantages to be gained by redesigning streets, for example as shared space, while others, such as campaigns like "Reclaim the Streets", a widespread "dis-organization", run a variety of events to physically reclaim the streets for political and artistic actions, often called street parties. David Engwicht is also a strong proponent of the concept that street life, rather than physical redesign, is the primary tool of street reclamation. See also References External links RTS — Reclaim the Streets Park(ing) – 22 September What if everyone had a car? by the BBC World News Document 2::: In game theory an uncorrelated asymmetry is an arbitrary asymmetry in a game which is otherwise symmetrical. The name 'uncorrelated asymmetry' is due to John Maynard Smith who called payoff relevant asymmetries in games with similar roles for each player 'correlated asymmetries' (note that any game with correlated asymmetries must also have uncorrelated asymmetries). The explanation of an uncorrelated asymmetry usually makes reference to "informational asymmetry". Which may confuse some readers, since, games which may have uncorrelated asymmetries are still games of complete information . What differs between the same game with and without an uncorrelated asymmetry is whether the players know which role they have been assigned. If players in a symmetric game know whether they are Player 1, Player 2, etc. (or row vs. column player in a bimatrix game) then an uncorrelated asymmetry exists. If the players do not know which player they are then no uncorrelated asymmetry exists. The information asymmetry is that one player believes he is player 1 and the other believes he is player 2. Therefore, "informational asymmetry" does not refer to knowledge in the sense of an information set in an extensive form game. The concept of uncorrelated asymmetries is important in determining which Nash equilibria are evolutionarily stable strategies in discoordination games such as the game of chicken. In these games the mixing Nash is the ESS if there is no uncorrelated asymmetry, and the pure conditional Nash equilibria are ESSes when there is an uncorrelated asymmetry. The usual applied example of an uncorrelated asymmetry is territory ownership in the hawk-dove game. Even if the two players ("owner" and "intruder") have the same payoffs (i.e., the game is payoff symmetric), the territory owner will play Hawk, and the intruder Dove, in what is known as the 'Bourgeois strategy' (the reverse is also an ESS known as the 'anti-bourgeois strategy', but makes little biologi Document 3::: HD 28700 (HR 1433) is a solitary star in the southern constellation Caelum. It has an apparent magnitude of 6.12, making it visible to the naked eye under ideal conditions. Parallax measurements place the object at a distance of 384 light years and is currently receding with a heliocentric radial velocity of . HD 28700 has a stellar classification of K1 III, indicating that it is a red giant. It has three times the Sun's mass and has expanded to ten times its radius. It radiates at 56 times the Sun's luminosity from its swollen photosphere at an effective temperature of , giving it an orange hue. HD 28700 has a projected rotational velocity too low to be measured accurately due to it being less than . HD 28700 has 120% the abundance of iron relative to the Sun. At a modeled age of 377 million years, HD 28700 is on the red giant branch fusing hydrogen in a shell around an inert helium core. The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is one of the primary advantages of using the Schmidt–Kalman filter over increasing the dimensionality of the state space? A. Improved accuracy in bias estimation B. Reduction in computational complexity C. Enhanced ability to observe residual biases D. Simplicity in linear state transition models Answer:
B. Reduction in computational complexity
Relavent Documents: Document 0::: NGC 2197 is an centrally condensed open cluster within the Large Magellanic Cloud, in the Dorado constellation. It is estimated to be 400 million years old. Document 1::: The Temple of Friendship () is a small, round building in Sanssouci Park, Potsdam, in Germany. It was built by King Frederick II of Prussia in memory of his sister, Princess Wilhelmine of Prussia, who died in 1758. The building, in the form of a classical temple, was built south of the park's main boulevard between 1768 and 1770 by architect Carl von Gontard. It complements the Temple of Antiquities, which lies due north of the boulevard on an axis with the Temple of Friendship. The First Pavilion in Neuruppin A notable precursor of the Temple of Friendship was the smaller Temple of Apollo constructed in 1735 at Neuruppin, where Crown Prince Frederick (later Frederick II) resided from 1732 to 1735 as the commander of a regiment stationed there. The first building designed by Georg Wenzeslaus von Knobelsdorff, the Temple of Apollo was situated in the Amalthea Garden, a flower and vegetable garden created by Frederick. The Temple of Apollo was an open, round temple, although in 1791 it was enclosed by brick walls between its columns. In August 1735, Frederick wrote to his sister Wilhelmine, who at that time was already married and living in Bayreuth: "The garden house is a temple of eight Doric columns holding up a domed roof. On it stands a statue of Apollo. As soon as it is finished, we shall offer sacrifices in it – naturally to you, dear sister, protectress of the fine arts." The Pavilion in Sanssouci Park To honor the memory of Wilhelmine, Frederick chose, as he had in Neuruppin, the form of an open, round temple with a shallow domed roof supported by eight Corinthian columns. This architectural structure, the monopteros type, has its origins in ancient Greece, where such buildings were erected over cult statues and tombstones. In a shallow alcove at the back wall of the temple is a life-sized statue of Wilhelmine of Bayreuth, holding a book in her hand. The marble figure is from the workshop of the sculptor brothers Johann David and Johann Lorenz Wilh Document 2::: IC 335 is an edge-on lenticular galaxy about 60 million light years (18 million parsecs) away, in the constellation Fornax. It is part of the Fornax Cluster. IC 335 appears very similar to NGC 4452, a lenticular galaxy in Virgo. Both galaxies are edge-on, meaning that their characteristics, like spiral arms, are hidden. Lenticular galaxies like these are thought to be intermediate between spiral galaxies and elliptical galaxies, and like elliptical galaxies, they have very little gas for star formation. IC 335 may have once been a spiral galaxy that ran out of interstellar medium, or it may have collided with a galaxy in the past and thus used up all of its gas (see interacting galaxy). References External links Document 3::: Ortho effect is an organic chemistry phenomenon where the presence of a chemical group at the at ortho position or the 1 and 2 position of a phenyl ring, relative to the carboxylic compound changes the chemical properties of the compound. This is caused by steric effects and bonding interactions along with polar effects caused by the various substituents which are in a given molecule, resulting in changes in its chemical and physical properties. The ortho effect is associated with substituted benzene compounds. There are three main ortho effects in substituted benzene compounds: Steric hindrance forces cause substitution of a chemical group in the ortho position of benzoic acids become stronger acids. Steric inhibition of protonation caused by substitution of anilines to become weaker bases, compared to substitution of isomers in the meta and para position. Electrophilic aromatic substitution of disubstituted benzene compounds causes steric effects which determines the regioselectivity of an incoming electrophile in disubstituted benzene compounds Ortho substituted benzoic acids When a substituent group is located ortho position to the carboxyl group in a substituted benzoic acid compound, the compound becomes more acidic surpassing the unmodified benzoic acid. Generally ortho-substituted benzoic acids are stronger acids than their meta and para isomers. Mechanism of action When ortho substitution occurs in benzoic acid, steric hindrance causes the carboxyl group to twist out of the plane of the benzene ring. The twisting inhibits the resonance of the carboxyl group with the phenyl ring, leading to increased acidity of the carboxyl group. This increased acidity contrasts with the reduced acidity caused by destabilizing cross-conjugation. The destabilizing cross-conjugation causes decreased acidity of benzoic acid compared to formic acid. pKa values The table given below shows pKa values of various monosubstituted benzoic acids. Ortho substituted aniline The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the role of the Eco1/Ctf7 gene in the establishment of sister chromatid cohesion during the cell cycle? A. It is required for maintaining cohesion after S phase. B. It is necessary for the initial loading of cohesin on chromosomes. C. It acetylates lysine residues in the Smc3 subunit of cohesin during S phase. D. It interacts with chromatin-associated cohesin only in G1 phase. Answer:
C. It acetylates lysine residues in the Smc3 subunit of cohesin during S phase.
Relavent Documents: Document 0::: In quantum mechanics, the Schrödinger equation describes how a system changes with time. It does this by relating changes in the state of the system to the energy in the system (given by an operator called the Hamiltonian). Therefore, once the Hamiltonian is known, the time dynamics are in principle known. All that remains is to plug the Hamiltonian into the Schrödinger equation and solve for the system state as a function of time. Often, however, the Schrödinger equation is difficult to solve (even with a computer). Therefore, physicists have developed mathematical techniques to simplify these problems and clarify what is happening physically. One such technique is to apply a unitary transformation to the Hamiltonian. Doing so can result in a simplified version of the Schrödinger equation which nonetheless has the same solution as the original. Transformation A unitary transformation (or frame change) can be expressed in terms of a time-dependent Hamiltonian and unitary operator . Under this change, the Hamiltonian transforms as: . The Schrödinger equation applies to the new Hamiltonian. Solutions to the untransformed and transformed equations are also related by . Specifically, if the wave function satisfies the original equation, then will satisfy the new equation. Derivation Recall that by the definition of a unitary matrix, . Beginning with the Schrödinger equation, , we can therefore insert the identity at will. In particular, inserting it after and also premultiplying both sides by , we get . Next, note that by the product rule, . Inserting another and rearranging, we get . Finally, combining (1) and (2) above results in the desired transformation: . If we adopt the notation to describe the transformed wave function, the equations can be written in a clearer form. For instance, can be rewritten as , which can be rewritten in the form of the original Schrödinger equation, The original wave function can be recovered as . Relation to Document 1::: Ogataea is a genus of ascomycetous yeasts in the family Saccharomycetaceae. It was separated from the former genus Hansenula via an examination of their 18S and 26S rRNA partial base sequencings by Yamada et al. 1994. The genus name of Ogataea is in honour of Koichi Ogata (x - 1977), who was a Japanese microbiologist from the Department of Agricultural Chemistry, Faculty of Agriculture, at Kyoto University. It was stated in the journal; "The genus is named in honor of the late Professor Dr. Koichi Ogata, Department of Agricultural Chemistry, Faculty of Agriculture, Kyoto University, Kyoto, Japan, in recognition of his studies on the oxidation and assimilation of methanol (C1 compound) in methanol-utilizing yeasts." The genus was circumscribed by Yuzo Yamada, Kojiro Maeda and Kozaburo Mikata in Biosc., Biotechn. Biochem. vol.58 (Issue 7) on page 1253 in 1994. Diagnosis Like other yeasts, also the species within the genus Ogataea are single-celled or build pseudohyphae of only a few elongated cells; true hyphae are not formed. They are able to reproduce sexually or asexually. The latter case happens with a cell division by multilateral budding on a narrow base with spherical to ellipsoidal budded cells. In the sexual reproduction the asci are deliquescent and may be unconjugated or show conjugation between a cell and its bud or between independent cells. Asci produce one to four, sometimes more, ascospores which are hat-shaped, allantoid or spherical with a ledge. The species are homothallic or infrequently heterothallic. Ogataea cells are able to ferment glucose or other sugars and some species assimilate nitrate. All known species are able to utilize methanol as carbon source. The predominant ubiquinone is coenzyme Q-7 and the diazonium blue B test is negative. Some species are used and cultured for microbiological and genetic research e.g. Ogataea polymorpha, Ogataea minuta or Ogataea methanolica. Ogataea minuta (Wickerham) Y. Yamada, K. Maeda & Mikata is th Document 2::: An explosimeter is a gas detector which is used to measure the amount of combustible gases present in a sample. When a percentage of the lower explosive limit (LEL) of an atmosphere is exceeded, an alarm signal on the instrument is activated. The device, also called a combustible gas detector, operates on the principle of resistance proportional to heat—a wire is heated, and a sample of the gas is introduced to the hot wire. Combustible gases burn in the presence of the hot wire, thus increasing the resistance and disturbing a Wheatstone bridge, which gives the reading. A flashback arrestor is installed in the device to avoid the explosimeter igniting the sample external to the device. Note, that the detection readings of an explosimeter are only accurate if the gas being sampled has the same characteristics and response as the calibration gas. Most explosimeters are calibrated to methane, hydrogen, and carbon monoxide. Explosimeters are important because workspaces may contain a flammable or explosive atmosphere due to the accumulation of flammable gases or vapors. Sparks from ordinary battery-powered portable equipment, including cameras, cell phones, laptop computers, or anything else located on the job site may serve as an ignition source. The explosimeter warns the user of dangerous atmospheric conditions before a possible explosion can occur. Explosimetry Explosimetry simply means the measurement of flammable or explosive conditions, normally in the atmosphere around us. In modern times, jobsites both above ground and below ground can have a wide range of dangerous flammable materials present. The danger of these flammable materials are mitigated by detection systems. Explosimetry sensors are integrated into stationary and portable devices to detect the concentration of the calibrated gas in air. The explosimeter is an example of a detection system with an explosimetry sensor in it. For explosimeters to work properly they must be calibrated for a parti Document 3::: The Chicago Lake Tunnel was the first of several tunnels built from the city of Chicago's shore on Lake Michigan two miles out into the lake to access unpolluted fresh water far from the city's sewage. Waterborne disease in early Chicago In the early decades of its existence, the growing city was only about three feet above the surface of Lake Michigan, and the areas of early European settlement were flat and sandy with a high water table. European settlers in Chicago only needed to dig 6 to 12 feet to create a private well. The same settlers, however, would also dig privy vaults for human waste nearby. Because the sandy soil topped a layer of hard clay, human waste would sink from the outhouse, meet the impervious clay, and travel laterally into the freshwater supply. As a result, Chicago suffered numerous widespread outbreaks of waterborne diseases. The Chicago Board of Health was organized in 1835, in response to the threat of a cholera epidemic, and later outbreaks of cholera in 1852 and 1854 killed thousands. Chesbrough's Water Plan In 1855 the city’s newly formed Board of Sewerage Commissioners hired the 42-year-old Ellis S. Chesbrough (1813–1886), the first city engineer of Boston to study the problem. In 1863, Chesbrough completed a design for a water and sewer system for the city that included a tunnel five feet wide and lined with brick that would extend through the clay bed of Lake Michigan to a distance of 10,567 feet. Work started in 1864 and the tunnel was opened in 1867. Construction Gravity forces water into the tunnel through a structure called a crib. The crib for the Lake Tunnel was forty feet high and had five sides. Each side was fifty-eight feet long. The crib had outer, middle, inner walls bolted together, and each was sealed with caulk and tar in the same way ships of the day were made. The crib comprised fifteen separate water-tight compartments with an opening at the bottom twenty-five feet in diameter referred to as "the well," which d The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What role does the Foundation for Biomedical Research (FBR) play in relation to animal research? A. It advocates against the use of animals in research. B. It informs various groups about the necessity of animal research in medicine. C. It solely focuses on legislative activism related to animal rights. D. It provides funding exclusively for research on nonhuman primates. Answer:
B. It informs various groups about the necessity of animal research in medicine.
Relavent Documents: Document 0::: This is a list of simultaneous localization and mapping (SLAM) methods. The KITTI Vision Benchmark Suite website has a more comprehensive list of Visual SLAM methods. List of methods EKF SLAM FastSLAM 1.0 FastSLAM 2.0 L-SLAM (Matlab code) QSLAM GraphSLAM Occupancy Grid SLAM DP-SLAM Parallel Tracking and Mapping (PTAM) LSD-SLAM (available as open-source) S-PTAM (available as open-source) ORB-SLAM (available as open-source) ORB-SLAM2 (available as open-source) ORB-SLAM3 (available as open-source) OrthoSLAM MonoSLAM GroundSLAM CoSLAM SeqSlam iSAM (Incremental Smoothing and Mapping) CT-SLAM (Continuous Time) - referred to as Zebedee (SLAM) RGB-D SLAM BranoSLAM Kimera (open-source) Wildcat-SLAM References Document 1::: The Debus–Radziszewski imidazole synthesis is a multi-component reaction used for the synthesis of imidazoles from a 1,2-dicarbonyl, an aldehyde, and ammonia or a primary amine. The method is used commercially to produce several imidazoles. The process is an example of a multicomponent reaction. The reaction can be viewed as occurring in two stages. In the first stage, the dicarbonyl and two ammonia molecules condense with the two carbonyl groups to give a diimine: In the second stage, this diimine condenses with the aldehyde: However, the actual reaction mechanism is not certain. This reaction is named after Heinrich Debus and . A modification of this general method, where one equivalent of ammonia is replaced by an amine, affords N-substituted imidazoles in good yields. This reaction has been applied to the synthesis of a range of 1,3-dialkylimidazolium ionic liquids by using various readily available alkylamines. References Document 2::: Heteroduplex analysis (HDA) is a method in biochemistry used to detect point mutations in DNA (Deoxyribonucleic acid) since 1992. Heteroduplexes are dsDNA molecules that have one or more mismatched pairs, on the other hand homoduplexes are dsDNA which are perfectly paired. This method of analysis depend up on the fact that heteroduplexes shows reduced mobility relative to the homoduplex DNA. heteroduplexes are formed between different DNA alleles. In a mixture of wild-type and mutant amplified DNA, heteroduplexes are formed in mutant alleles and homoduplexes are formed in wild-type alleles. There are two types of heteroduplexes based on type and extent of mutation in the DNA. Small deletions or insertion create bulge-type heteroduplexes which is stable and is verified by electron microscope. Single base substitutions creates more unstable heteroduplexes called bubble-type heteroduplexes, because of low stability it is difficult to visualize in electron microscopy. HDA is widely used for rapid screening of mutation of the 3 bp p.F508del deletion in the CFTR gene. Document 3::: Repeated implantation failure (RIF) is the repeated failure of the embryo to implant onto the side of the uterus wall following IVF treatment. Implantation happens at 6–7 days after conception and involves the embedding of the growing embryo into the mothers uterus and a connection being formed. A successful implantation can be determined by using an ultrasound to view the sac which the baby grows in, inside the uterus. However, the exact definition of RIF is debated. Recently the most commonly accepted definition is when a woman under 40 has gone through three unsuccessful cycles of IVF, when in each cycle four good quality eggs have been transferred. Repeated implantation failure should not be confused with recurrent IVF failure. Recurrent IVF failure is a much more broad term and includes all repeated failures to get pregnant from IVF. Repeated implantation failure specifically refers to those failures due to unsuccessful implanting to the uterus wall. An unsuccessful implantation can result from problems with the mother or with the embryo. It is essential that the mother and embryo are able to communicate with each other during all stages of pregnancy, and an absence of this communication can lead to an unsuccessful implantation and a further unsuccessful pregnancy. Contributing maternal factors During implantation, the embryo must cross the epithelial layer of the maternal endometrium before invading and implanting in the stroma layer. Maternal factors, including congenital uterine abnormalities, fibroids, endometrial polyps, intrauterine adhesions, adenomyosis, thrombophilia and endometriosis, can reduce the chances of implantation and result in RIF. Congenital uterine abnormalities Congenital uterine abnormalities are irregularities in the uterus which occur during the mothers foetal development. Hox genes Two Hox genes have been identified to assist in the development and receptivity of the uterus and endometrium, Hoxa10 and Hoxa11. Hoxa10 has been s The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What significant event occurred on September 9, 1942, in the Siskiyou National Forest? A. The establishment of the forest B. A bombing incident by a Japanese airplane C. The first recorded fire in the forest D. The combination of Rogue River and Siskiyou National Forests Answer:
B. A bombing incident by a Japanese airplane
Relavent Documents: Document 0::: The Commodore LCD (sometimes known in short as the CLCD) is an unreleased LCD-equipped laptop made by Commodore International. It was presented at the January 1985 Consumer Electronics Show, but never released. The CLCD was not directly compatible with other Commodore home computers, but its built-in Commodore BASIC 3.6 interpreter could run programs written in the Commodore 128's BASIC 7.0, as long as these programs did not include system-specific POKE commands. Like the Commodore 264 and Radio Shack TRS-80 Model 100 series computers, the CLCD had several built-in ROM-based office application programs. The CLCD featured a 1 MHz Rockwell 65C102 CPU (a CMOS 6502 variant) and 32 KB of RAM (expandable to 64 KB internally). The BASIC interpreter and application programs were built into 96 KB of ROM. References Document 1::: The Bas Saharan Basin () is an artesian aquifer system which covers most of the Algerian and Tunisian Sahara and extends to Libya, enclosing the whole of the Grand Erg Oriental. References Document 2::: WTX (for Workstation Technology Extended) was a motherboard form factor specification introduced by Intel at the IDF in September 1998, for its use at high-end, multiprocessor, multiple-hard-disk servers and workstations. The specification had support from major OEMs (Compaq, Dell, Fujitsu, Gateway, Hewlett-Packard, IBM, Intergraph, NEC, Siemens Nixdorf, and UMAX) and motherboard manufacturers (Acer, Asus, Supermicro and Tyan) and was updated (1.1) in February 1999. , the specification has been discontinued and the URL www.wtx.org no longer hosts a website and has not been owned by Intel since at least 2004. This form factor was geared specifically towards the needs of high-end systems, and included specifications for a WTX power supply unit (PSU) using two WTX-specific 24-pin and 22-pin Molex connectors. The WTX specification was created to standardize a new motherboard and chassis form factor, fix the relative processor location, and allow for high volume airflow through a portion of the chassis where the processors are positioned. This allowed for standard form factor motherboards and chassis to be used to integrate processors with more demanding thermal management requirements. Bigger than ATX, maximum WTX motherboard size was . This was intended to provide more room in order to accommodate higher numbers of integrated components. WTX computer cases were backwards compatible with ATX motherboards (but not vice versa), and sometimes came equipped with ATX power supplies. Document 3::: A launch loop, or Lofstrom loop, is a proposed system for launching objects into orbit using a moving cable-like system situated inside a sheath attached to the Earth at two ends and suspended above the atmosphere in the middle. The design concept was published by Keith Lofstrom and describes an active structure maglev cable transport system that would be around 2,000 km (1,240 mi) long and maintained at an altitude of up to 80 km (50 mi). A launch loop would be held up at this altitude by the momentum of a belt that circulates around the structure. This circulation, in effect, transfers the weight of the structure onto a pair of magnetic bearings, one at each end, which support it. Launch loops are intended to achieve non-rocket spacelaunch of vehicles weighing 5 metric tons by electromagnetically accelerating them so that they are projected into Earth orbit or even beyond. This would be achieved by the flat part of the cable which forms an acceleration track above the atmosphere. The system is designed to be suitable for launching humans for space tourism, space exploration and space colonization, and provides a relatively low 3g acceleration. History Launch loops were described by Keith Lofstrom in November 1981 Reader's Forum of the American Astronautical Society News Letter, and in the August 1982 L5 News. In 1982, Paul Birch published a series of papers in Journal of the British Interplanetary Society which described orbital rings and described a form which he called Partial Orbital Ring System (PORS). The launch loop idea was worked on in more detail around 1983–1985 by Lofstrom. It is a fleshed-out version of PORS specifically arranged to form a mag-lev acceleration track suitable for launching humans into space, but whereas the orbital ring used superconducting magnetic levitation, launch loops use electromagnetic suspension (EMS). Description Consider a large cannon on an island that shoots a shell into the high atmosphere. The shell will follow a The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the primary purpose of a memory protection unit (MPU) in computer systems? A. To manage virtual memory for applications B. To provide memory protection and prevent unauthorized access C. To enhance the speed of data processing D. To control power consumption in processors Answer:
B. To provide memory protection and prevent unauthorized access
Relavent Documents: Document 0::: A caruncle is defined as 'a small, fleshy excrescence that is a normal part of an animal's anatomy'. Within this definition, caruncles in birds include wattles (or dewlaps), combs, snoods, and earlobes. The term caruncle is derived from Latin caruncula, the diminutive of carō, "flesh". Taxonomy Caruncles are carnosities, often of bright colors such as red, blue, yellow or white. They can be present on the head, neck, throat, cheeks or around the eyes of some birds. They may be present as combs or crests and other structures near the beak, or, hanging from the throat or neck. Caruncles may be featherless, or, have small scattered feathers. In some species, they may form pendulous structures of erectile tissue, such as the snood of the domestic turkey. Caruncles are sometimes secondary sexual characteristics, having a more intense color or even a different color, developing as the male reaches sexual maturity. Function Caruncles are also ornamental elements used by males to attract females to breeding. Having large caruncles or colorful bright ones indicates high levels of testosterone, that they are well-fed birds able to elude other predators thus showing the good quality of their genes. It has been proposed that these organs are also associated with genes which encode resistance to disease. It is believed that for birds living in tropical regions, the caruncles also play a role in thermoregulation, making the blood cool faster when flowing through them. Turkeys In turkeys, the term usually refers to small, bulbous, fleshy protuberances found on the head, neck and throat, with larger structures particularly at the bottom of the throat. The wattle is a flap of skin hanging under the chin connecting the throat and head and the snood is a highly erectile appendage emanating from the forehead. Both sexes of turkey possess caruncles, although they are more pronounced in the male. Usually they are pale, but when the male becomes excited or during courtship, the Document 1::: Apache Flink is an open-source, unified stream-processing and batch-processing framework developed by the Apache Software Foundation. The core of Apache Flink is a distributed streaming data-flow engine written in Java and Scala. Flink executes arbitrary dataflow programs in a data-parallel and pipelined (hence task parallel) manner. Flink's pipelined runtime system enables the execution of bulk/batch and stream processing programs. Furthermore, Flink's runtime supports the execution of iterative algorithms natively. Flink provides a high-throughput, low-latency streaming engine as well as support for event-time processing and state management. Flink applications are fault-tolerant in the event of machine failure and support exactly-once semantics. Programs can be written in Java, Python, and SQL and are automatically compiled and optimized into dataflow programs that are executed in a cluster or cloud environment. Flink does not provide its own data-storage system, but provides data-source and sink connectors to systems such as Apache Doris, Amazon Kinesis, Apache Kafka, HDFS, Apache Cassandra, and ElasticSearch. Development Apache Flink is developed under the Apache License 2.0 by the Apache Flink Community within the Apache Software Foundation. The project is driven by 119 committers and over 340 contributors. Overview Apache Flink's dataflow programming model provides event-at-a-time processing on both finite and infinite datasets. At a basic level, Flink programs consist of streams and transformations. “Conceptually, a stream is a (potentially never-ending) flow of data records, and a transformation is an operation that takes one or more streams as input, and produces one or more output streams as a result.” Apache Flink includes two core APIs: a DataStream API for bounded or unbounded streams of data and a DataSet API for bounded data sets. Flink also offers a Table API, which is a SQL-like expression language for relational stream and batch processing Document 2::: Erich Otto Engel (29 September 1866, in Alt-Malisch Frankfurt – 11 February 1944, in Dachau) was a German entomologist, who specialised in Diptera. He was a graphic artist and administrator of the Diptera collection in Zoologische Staatssammlung München. Selected works Engel, E. O. (1925) Neue paläarktische Asiliden (Dipt.). Konowia. 4, 189-194. Engel, E. O., & Cuthbertson A. (1934) Systematic and biological notes on some Asilidae of Southern Rhodesia with a description of a species new to science. Proceedings of the Rhodesia Scientific Association. 34, Engel, E.O. 1930. Asilidae (Part 24), in E. Lindner (ed.) Die Fliegen der Paläarktischen Region, vol. 4. Schweizerbart'sche, Stuttgart. 491 pp. Engel, E.O. 1938-1954 Empididae. in Lindner, E. (Ed.). Die Fliegen der Paläarktischen Region, vol.4, 28, 1-400. Engel, E. O., & Cuthbertson A. (1939). Systematic and biological notes on some brachycerous Diptera of southern Rhodesia. Journal of the Entomological Society of Southern Africa. 2, 181–185. References Anonym 1936: [Engel, E. O.] Insektenbörse, Stuttgart 53 (37) Horn, W. 1936: [Engel, E. O.] Arb. morph. taxon. Ent. Berlin-Dahlem, Berlin 3 (4) 301* Reiss, F. 1992: Die Sektion Diptera der Zoologischen Staatssammlung München. Spixiana Suppl., München 17 : 72-82, 9 Abb. 72-75, Portrait External links DEI Portrait Document 3::: In mathematics, the Browder–Minty theorem (sometimes called the Minty–Browder theorem) states that a bounded, continuous, coercive and monotone function T from a real, separable reflexive Banach space X into its continuous dual space X∗ is automatically surjective. That is, for each continuous linear functional g ∈ X∗, there exists a solution u ∈ X of the equation T(u) = g. (Note that T itself is not required to be a linear map.) The theorem is named in honor of Felix Browder and George J. Minty, who independently proved it. See also Pseudo-monotone operator; pseudo-monotone operators obey a near-exact analogue of the Browder–Minty theorem. References (Theorem 10.49) The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the primary purpose of botanical gardens in Bulgaria? A. To showcase only native species B. To preserve global plant diversity C. To serve as private recreational spaces D. To exclusively collect endemic species Answer:
B. To preserve global plant diversity
Relavent Documents: Document 0::: Introduced by Martin Hellman and Susan K. Langford in 1994, the differential-linear attack is a mix of both linear cryptanalysis and differential cryptanalysis. The attack utilises a differential characteristic over part of the cipher with a probability of 1 (for a few rounds—this probability would be much lower for the whole cipher). The rounds immediately following the differential characteristic have a linear approximation defined, and we expect that for each chosen plaintext pair, the probability of the linear approximation holding for one chosen plaintext but not the other will be lower for the correct key. Hellman and Langford have shown that this attack can recover 10 key bits of an 8-round DES with only 512 chosen plaintexts and an 80% chance of success. The attack was generalised by Eli Biham et al. to use differential characteristics with probability less than 1. Besides DES, it has been applied to FEAL, IDEA, Serpent, Camellia, and even the stream cipher Phelix. References Document 1::: Sir Richard Spencer (1593 − 1 November 1661) was an English nobleman, gentleman, knight, and politician who sat in the House of Commons from 1621 to 1629 and in 1661. He supported the Royalist cause in the English Civil War. Early life Spencer was the son of Robert Spencer, 1st Baron Spencer of Wormleighton and his wife Margaret, daughter of Sir Francis Willoughby and Elizabeth Lyttelton. He was baptised on 21 October 1593. He was educated at Corpus Christi College, Oxford in 1609 and was awarded BA in 1612. His brothers were Sir Edward Spencer, Sir John Spencer, and William Spencer, 2nd Baron Spencer of Wormleighton. Parliamentary career In 1621, Spencer was selected Member of Parliament for Northampton. He was a student of Gray's Inn in 1624. In 1624 and 1625 he was re-elected MP for Northampton. He became a gentleman of the bedchamber in 1626. He was re-elected MP for Northampton in 1626 and 1628 and sat until 1629 when King Charles decided to rule without parliament for eleven years. Post-parliament actions He was a J.P. for Kent by 1636. Spencer stood for parliament for Kent for the Long Parliament in November 1640, but withdrew before the election took place. He was imprisoned twice by the Long Parliament for promoting the moderate Kentish petition of 1642. He was a commissioner of array for the King in 1642, stood security for loans amounting to £60,000 and helped to raise two regiments of horse, which he commanded at the Battle of Edgehill. He gave up his command in 1643 and was claimed the benefit of the Oxford Articles. He settled £40 a year on the minister of Orpington and was allowed to compound for a mere £300. However he became involved in the canal schemes of William Sandys and his financial condition became precarious. In 1651 he obtained a pass to France for himself and his family and settled in Brussels. He returned to England in about 1653 and was imprisoned and forced to pay off his debts. At the Restoration, Spencer petitioned unsucce Document 2::: The Declaration of Tokyo is a set of international guidelines for physicians concerning torture and other cruel, inhuman or degrading treatment or punishment in relation to detention and imprisonment, which was adopted in October 1975 during the 29th General assembly of the World Medical Association, and later editorially updated by the WMA in France, May 2005 and 2006. It declares torture to be "contrary to the laws of humanity", and antithetical to the "higher purpose" of the physician, which is to "alleviate the distress of his or her fellow human being." The policy states that doctors should refuse to participate in, condone, or give permission for torture, degradation, or cruel treatment of prisoners or detainees. According to the policy, a prisoner who refuses to eat should not be fed artificially against their will, provided that they are judged to be rational. References External links WMA Declaration of Tokyo - Guidelines for Physicians Concerning Torture and other Cruel, Inhuman or Degrading Treatment or Punishment in Relation to Detention and Imprisonment Document 3::: A hawk is a tool used to hold a plaster, mortar, or a similar material, so that the user can repeatedly, quickly and easily get some of that material on the tool which then applies it to a surface. A hawk consists of a board about 13 inches square with a perpendicular handle fixed centrally on the reverse. The user holds the hawk horizontally with the non-dominant hand and applies the material on the hawk with a tool held in the dominant hand. Hawks are most often used by plasterers, along with finishing trowels, to apply a smooth finish of plaster to a wall. Brick pointers use hawks to hold mortar while they work. Hawks are also used to hold joint compound for taping and jointing. The name "hawk" probably derives from the way the object rides on the user's arm, like a bird of prey. References de:Glättkelle The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What are the three main stages of the human action cycle as proposed by Donald A. Norman? A. Goal formation, Execution, Evaluation B. Planning, Execution, Review C. Formation, Execution, Assessment D. Goal setting, Action, Outcome Answer:
A. Goal formation, Execution, Evaluation
Relavent Documents: Document 0::: James Wood (14 December 1760 – 23 April 1839) was a mathematician, and Master of St John's College, Cambridge. In his later years he was Dean of Ely. Life Wood was born in Holcombe, Bury where his father ran an evening school and taught his son the elements of arithmetic and algebra. From Bury Grammar School he proceeded to St John's College, Cambridge in 1778, graduating as senior wrangler in 1782. On graduating he became a fellow of the college and in his long tenure there produced several successful academic textbooks for students of mathematics. Between 1795 and 1799 his The principles of mathematics and natural philosophy, was printed, in four volumes, by J. Burges. Vol.I: 'The elements of algebra', by Wood; Vol.II: 'The principles of fluxions' by Samuel Vince; Vol.III Part I: 'The principles of mechanics" by Wood; and Vol.III Part II: "The principles of hydrostatics" by Samuel Vince; Vol.IV "The principles of astronomy" by Samuel Vince. Three other volumes -"A treatise on plane and spherical trigonometry" and "The elements of the conic sections" by Samuel Vince (1800) and "The elements of optics" by Wood (1801" may have been issued as part of the series. Wood remained for sixty years at St. John's, serving as both President (1802–1815) and Master (1815–1839); on his death in 1839 he was interred in the college chapel and bequeathed his extensive library to the college, comprising almost 4,500 printed books on classics, history, mathematics, theology and travel, dating from the 17th to the 19th centuries. Wood was also ordained as a priest in 1787 and served as Dean of Ely from 1820 until his death. Publications The Elements of Algebra (1795) The Principles of Mechanics (1796) The Elements of Optics (1798) References Notes Other sources W. W. Rouse Ball, A History of the Study of Mathematics at Cambridge University, 1889, repr. Cambridge University Press, 2009, , p. 110 Document 1::: The Dublin Institute of Technology (DIT) School of Electrical and Electronic Engineering (SEEE) was the largest and one of the longest established Schools of Electrical and Electronic Engineering in Ireland. It was located at the DIT Kevin Street Campus in Dublin City, as part of the College of Engineering & Built Environment (CEBE). In 2019, DIT along with the Institute of Technology Blanchardstown (ITB) and the Institute of Technology Tallaght (ITT) became the founding institutes of the new Technological University Dublin (TU Dublin). Overview The DIT School of Electrical and Electronic Engineering was the largest education provider of Electrical and Electronic Engineering in Ireland in terms of programme diversity, staff and student numbers, covering a wide range of engineering disciplines including; Communications Engineering, Computer Engineering, Power Engineering, Electrical Services Engineering, Control Engineering, Energy Management and Electronic Engineering. The school included well established research centres in areas such as photonics, energy, antennas, communications and electrical power, with research outputs in; biomedical engineering, audio engineering, sustainable design, assistive technology and health informatics. Educational courses in technical engineering commenced at Kevin St. Dublin 8 in 1887. The school sought accreditation for its programmes from the appropriate Irish and international professional body organisations, such as the Institution of Engineers of Ireland, offering education across the full range of third level National Framework of Qualifications (NFQ) Levels, from Level 6 to Level 10 (apprenticeships to post-doctoral degrees). During the 2010s, the school delivered 23 individual programmes to over 1,200 students and had an output of approximately 350 graduates per year. In 2015, the head of the school was Professor Michael Conlon. In 2015, Electrical & Electronic Engineering was expected to be the first School from the C Document 2::: David Negrete Fernández () was a Mexican colonel who participated in the Mexican Revolution. He was also a musician. Biography David fought alongside military officer Felipe Ángeles as a part of División del Norte. He married Emilia Moreno Anaya, who bore him: Consuelo Negrete Moreno Jorge Alberto Negrete Moreno Emilia Negrete Moreno Teresa Negrete Moreno David Negrete Moreno Rubén Negrete Moreno David was a math teacher in Mexico City. He was also a father-in-law of Elisa Christy and María Félix. References Document 3::: A super seeder is a no-till planter, towed behind a tractor, that sows (plants) especially wheat seeds in rows directly without any prior seedbed preparation. It is operated with the PTO of the tractor and is connected to it with three-point linkage. The Super Seeder is an advanced agricultural machine than Happy seeder, engineered to revolutionize traditional farming methods. It offers an efficient, time-saving solution, allowing farmers to sow wheat seeds directly after rice harvest without the need for prior stubble burning, thereby contributing significantly to environmental preservation. It is mostly used to sow wheat seeds after the paddy harvest in North Indian states. Importance in stubble burning management Traditional wheat farming involves a series of steps such as clearing the harvested paddy fields by burning the leftover stubble, tilling the soil, and then sowing the seeds. This process is not only time-consuming and labor-intensive but also environmentally harmful. Stubble burning contributes to air pollution, exacerbating climate change effects and posing health risks to local communities. The Super Seeder eliminates these adverse effects by providing an integrated solution for planting wheat seeds. This machine cuts and uproots the paddy straw, sows the wheat seeds, and deposits the straw over the sown area as mulch in a single pass. Various Workshops are also organised by state agricultural universities for awareness regarding Importance of super seeder in Stubble Burning Management. The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What significant achievement did White Widow accomplish in 1995? A. It became a medical cannabis strain. B. It won the Cannabis Cup. C. It was developed by Mr. Nice Seedbank. D. It was renamed Black Widow. Answer:
B. It won the Cannabis Cup.
Relavent Documents: Document 0::: In the healthcare industry, information continuity is the process by which information relevant to a patient's care is made available to both the patient and the provider at the right place and the right time, to facilitate ongoing health care management and continuity of care. This is an extension of the concept of "Continuity of Care," which is defined by the American Academy of Family Physicians in their Continuity of Care definition as "the process by which the patient and the physician are cooperatively involved in ongoing health care management toward the goal of high quality, cost-effective medical care." There is a non-Information Technology reference to "Informational continuity" — the use of information on past events and personal circumstances to make current care appropriate for each individual. This exists with "Management continuity" and "Relational continuity." Information continuity in the information technology sense may exist alongside physical care continuity, such as when a medical chart arrives with a patient to the hospital. Information continuity may also be separate, such as when a patient's electronic records are sent to a treating physician before the patient arrives at a care site. Creating information continuity in health care typically involves the use of health information technology to link systems using standards. Information continuity will become more and more important as patients in health care systems expect that their treating physicians have all of their medical information across the health care spectrum. This use of this term in health information technology initiated at Seattle, Washington, at the Group Health Cooperative non-profit care system to describe activities including data sharing, allergy and medication reconciliation, and interfacing of data between health care institutions. See also Health care continuity References Document 1::: The following is a list of the 50 most populous incorporated cities in the U.S. state of Ohio. The population is according to the 2018 census estimates from the United States Census Bureau. Document 2::: Backward chaining (or backward reasoning) is an inference method described colloquially as working backward from the goal. It is used in automated theorem provers, inference engines, proof assistants, and other artificial intelligence applications. In game theory, researchers apply it to (simpler) subgames to find a solution to the game, in a process called backward induction. In chess, it is called retrograde analysis, and it is used to generate table bases for chess endgames for computer chess. Backward chaining is implemented in logic programming by SLD resolution. Both rules are based on the modus ponens inference rule. It is one of the two most commonly used methods of reasoning with inference rules and logical implications – the other is forward chaining. Backward chaining systems usually employ a depth-first search strategy, e.g. Prolog. Usage Backward chaining starts with a list of goals (or a hypothesis) and works backwards from the consequent to the antecedent to see if any data supports any of these consequents. An inference engine using backward chaining would search the inference rules until it finds one with a consequent (Then clause) that matches a desired goal. If the antecedent (If clause) of that rule is not known to be true, then it is added to the list of goals (for one's goal to be confirmed one must also provide data that confirms this new rule). For example, suppose a new pet, Fritz, is delivered in an opaque box along with two facts about Fritz: Fritz croaks Fritz eats flies The goal is to decide whether Fritz is green, based on a rule base containing the following four rules: If X croaks and X eats flies – Then X is a frog If X chirps and X sings – Then X is a canary If X is a frog – Then X is green If X is a canary – Then X is yellow With backward reasoning, an inference engine can determine whether Fritz is green in four steps. To start, the query is phrased as a goal assertion that is to be proven: "Fritz is green". 1. Fri Document 3::: Forest–savanna mosaic is a transitory ecotone between the tropical moist broadleaf forests of Equatorial Africa and the drier savannas and open woodlands to the north and south of the forest belt. The forest–savanna mosaic consists of drier forests, often gallery forest, interspersed with savannas and open grasslands. Flora This band of marginal savannas bordering the dense dry forest extends from the Atlantic coast of Guinea to South Sudan, corresponding to a climatic zone with relatively high rainfall, between 800 and 1400 mm. It is an often unresolvable, complex of secondary forests and mixed savannas, resulting from intense erosion of primary forests by fire and clearing. The vegetation ceases to have an evergreen character, and becomes more and more seasonal. A species of acacia, Faidherbia albida, marks, with its geographical distribution, the Guinean area of the savannas together with the area of the forest-savanna, arboreal and shrub, and a good part of the dense dry forest with prevalently deciduous trees. Ecoregions The World Wildlife Fund recognizes several distinct forest-savanna mosaic ecoregions: The Guinean forest–savanna mosaic is the transition between the Upper and Lower Guinean forests of West Africa and the West Sudanian savanna. The ecoregion extends from Senegal on the west to the Cameroon Highlands on the east. The Dahomey Gap is a region of Togo and Benin where the forest-savanna mosaic extends to the coast, separating the Upper and Lower Guinean forests. The Northern Congolian forest–savanna mosaic lies between the Congolian forests of Central Africa and the East Sudanian savanna. It extends from the Cameroon Highlands in the west to the East African Rift in the east, encompassing portions of Cameroon, Central African Republic, Democratic Republic of the Congo, and southwestern Sudan. The Western Congolian forest–savanna mosaic lies southwest of the Congolian forest belt, covering portions of southern Gabon, southern Republic of the Co The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the primary goal of information continuity in healthcare as defined in the text? A. To ensure that patients have access to all healthcare facilities B. To facilitate ongoing health care management and continuity of care C. To maintain a patient's personal information securely D. To reduce the cost of medical services Answer:
B. To facilitate ongoing health care management and continuity of care
Relavent Documents: Document 0::: Antifragility is a property of systems in which they increase in capability to thrive as a result of stressors, shocks, volatility, noise, mistakes, faults, attacks, or failures. The concept was developed by Nassim Nicholas Taleb in his book, Antifragile, and in technical papers. As Taleb explains in his book, antifragility is fundamentally different from the concepts of resiliency (i.e. the ability to recover from failure) and robustness (that is, the ability to resist failure). The concept has been applied in risk analysis, physics, molecular biology, transportation planning, engineering, aerospace (NASA), and computer science. Taleb defines it as follows in a letter to Nature responding to an earlier review of his book in that journal: Antifragile versus robust/resilient In his book, Taleb stresses the differences between antifragile and robust/resilient. "Antifragility is beyond resilience or robustness. The resilient resists shocks and stays the same; the antifragile gets better." The concept has now been applied to ecosystems in a rigorous way. In their work, the authors review the concept of ecosystem resilience in its relation to ecosystem integrity from an information theory approach. This work reformulates and builds upon the concept of resilience in a way that is mathematically conveyed and can be heuristically evaluated in real-world applications: for example, ecosystem antifragility. The authors also propose that for socio-ecosystem governance, planning or in general, any decision making perspective, antifragility might be a valuable and more desirable goal to achieve than a resilience aspiration. In the same way, Pineda and co-workers have proposed a simply calculable measure of antifragility, based on the change of “satisfaction” (i.e., network complexity) before and after adding perturbations, and apply it to random Boolean networks (RBNs). They also show that several well known biological networks such as Arabidopsis thaliana cell-cycle are as ex Document 1::: Otto Schmiedeknecht (8 September 1847 Bad Blankenburg, Thüringen- 11 February 1936, Blankenburg) was a German entomologist who specialised in Hymenoptera. Selected works 1902-1936.Opuscula Ichneumonologica. Blankenburg in Thüringen.1902pp. 1907.Hymenopteren Mitteleuropas. Gustav Fischer. Jena. 804pp. 1914.Die Schlupfwespen (Ichneumonidae) Mitteleuropas, insbesondere deutschlands. In: Schoeder C. "Die Insekten Mitteleuropas". Franckh'sche Verlagshandlung, Stuttgart. pp. 113–170. References Möller, R. 2000: [Schmiedeknecht, O.] Rudolst. Naturhist. Schr. 10 83-90 (Under 'Opuscula ichneumonlogica) Oehlke, J. 1968: Über den Verbleib der Hymenopteren-Typen Schmiedeknechts. Beitr. Ent. , Berlin 18: 319-327 Sources Stefan Vidal (2005). The history of Hymenopteran parasitoid research in Germany, Biological Control, 32 : 25-33. Document 2::: The 12-bit ND812, produced by Nuclear Data, Inc., was a commercial minicomputer developed for the scientific computing market. Nuclear Data introduced it in 1970 at a price under $10,000 (). Description The architecture has a simple programmed I/O bus, plus a DMA channel. The programmed I/O bus typically runs low to medium-speed peripherals, such as printers, teletypes, paper tape punches and readers, while DMA is used for cathode ray tube screens with a light pen, analog-to-digital converters, digital-to-analog converters, tape drives, disk drives. The word size, 12 bits, is large enough to handle unsigned integers from 0 to 4095 – wide enough for controlling simple machinery. This is also enough to handle signed numbers from -2048 to +2047. This is higher precision than a slide rule or most analog computers. Twelve bits could also store two six-bit characters (note, six-bit isn't enough for two cases, unlike "fuller" ASCII character set). "ND Code" was one such 6-bit character encoding that included upper-case alphabetic, digit, a subset of punctuation and a few control characters. The ND812's basic configuration has a main memory of 4,096 twelve-bit words with a 2 microsecond cycle time. Memory is expandable to 16K words in 4K word increments. Bits within the word are numbered from most significant bit (bit 11) to least significant bit (bit 0). The programming model consists of four accumulator registers: two main accumulators, J and K, and two sub accumulators, R and S. A rich set of arithmetic and logical operations are provided for the main accumulators and instructions are provided to exchange data between the main and sub accumulators. Conditional execution is provided through "skip" instructions. A condition is tested and the subsequent instruction is either executed or skipped depending on the result of the test. The subsequent instruction is usually a jump instruction when more than one instruction is needed for the case where the test fails. Document 3::: The Health Products and Food Branch (HPFB) of Health Canada manages the health-related risks and benefits of health products and food by minimizing risk factors while maximizing the safety provided by the regulatory system and providing information to Canadians so they can make healthy, informed decisions about their health. HPFB has ten operational Directorates with direct regulatory responsibilities: Biologics and Genetic Therapies Directorate Food Directorate Marketed Health Products Directorate (with responsibility for post-market surveillance) Medical Devices Directorate Natural Health Products Directorate Office of Nutrition Policy and Promotion Pharmaceutical Drugs Directorate Policy, Planning and International Affairs Directorate Resource Management and Operations Directorate Veterinary Drugs Directorate Extraordinary Use New Drugs Extraordinary Use New Drugs (EUNDs) is a regulatory programme under which, in times of emergency, drugs can be granted regulatory approval under the Food and Drug Act and its regulations. An EUND approved through this pathway can only be sold to federal, provincial, territorial and municipal governments. The text of the EUNDs regulations is available. On 25 March 2011 and after the pH1N1 pandemic, amendments were made to the Food and Drug Regulations (FDR) to include a specific regulatory pathway for EUNDs. Typically, clinical trials in human subjects are conducted and the results are provided as part of the clinical information package of a New Drug Submission (NDS) to Health Canada, the federal authority that reviews the safety and efficacy of human drugs. Health Canada recognizes that there are circumstances in which sponsors cannot reasonably provide substantial evidence demonstrating the safety and efficacy of a therapeutic product for NDS as there are logistical or ethical challenges in conducting the appropriate human clinical trials. The EUND pathway was developed to allow a mechanism for authorization of th The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is one common benchmark used to define a small state in terms of population? A. Less than 500,000 people B. Less than 1 million people C. Less than 1.5 million people D. Less than 2 million people Answer:
B. Less than 1 million people
Relavent Documents: Document 0::: The Fischer oxazole synthesis is a chemical synthesis of an oxazole from a cyanohydrin and an aldehyde in the presence of anhydrous hydrochloric acid. This method was discovered by Emil Fischer in 1896. The cyanohydrin itself is derived from a separate aldehyde. The reactants of the oxazole synthesis itself, the cyanohydrin of an aldehyde and the other aldehyde itself, are usually present in equimolar amounts. Both reactants usually have an aromatic group, which appear at specific positions on the resulting heterocycle. A more specific example of Fischer oxazole synthesis involves reacting mandelic acid nitrile with benzaldehyde to give 2,5-diphenyl-oxazole. History Fischer developed the Fischer oxazole synthesis during his time at Berlin University. The Fischer oxazole synthesis was one of the first syntheses developed to produce 2,5-disubstituted oxazoles. Mechanism The Fischer oxazole synthesis is a type of dehydration reaction which can occur under mild conditions in a rearrangement of the groups that would not seem possible. The reaction occurs by dissolving the reactants in dry ether and passing through the solution dry, gaseous hydrogen chloride. The product, which is the 2,5-disubstituted oxazole, precipitates as the hydrochloride and can be converted to the free base by the addition of water or by boiling with alcohol. The cyanohydrins and aldehydes used for the synthesis are usually aromatic, however there have been instances where aliphatic compounds have been used. The first step of the mechanism is the addition of gaseous HCl to the cyanohydrin 1. The cyanohydrin abstracts the hydrogen from HCl while the chloride ion attacks the carbon in the cyano group. This first step results in the formation of an iminochloride intermediate 2, probably as the hydrochloride salt. This intermediate then reacts with the aldehyde; the lone pair of the nitrogen attacks the electrophilic carbonyl carbon on the aldehyde. The following step results in an SN2 attack fo Document 1::: Base Number (BN) is a measurement of basicity that is expressed in terms of the number of milligrams of potassium hydroxide per gram of oil sample (mg KOH/g). BN is an important measurement in petroleum products, and the value varies depending on its application. BN generally ranges from 6–8 mg KOH/g in modern lubricants, 7–10 mg KOH/g for general internal combustion engine use and 10–15 mg KOH/g for diesel engine operations. BN is typically higher for marine grade lubricants, approximately 15-80 mg KOH/g, as the higher BN values are designed to increase the operating period under harsh operating conditions, before the lubricant requires replacement. Oil Additives An oil formulation consists of the base or stock oil and oil additives. Most oil formulations contain basic additives and detergents, designed to react with and neutralise acids, preventing damage to engine parts, including corrosion of metal surfaces. Potentiometric determination Although IP Standard test methods exist, the more common methods for BN are ASTM standardised, such as the potentiometric titration for fresh oils (Test method BN ASTM D2896). A sample is typically dissolved in a pre-mixed solvent of chlorobenzene and acetic acid and titrated with standardised perchloric acid in glacial acetic acid for fresh oil samples. The end point is detected using a glass electrode which is immersed in an aqueous solution containing the sample, and connected to a voltmeter/potentiometer. This causes an ion exchange in the outer solvated layer at the glass membrane, so a change in potential is generated which can be measured by the electrode. When the end point of the chemical reaction is reached, which is shown by an inflection point on the titration curve using a specified detection system, the amount of titrant required is used to generate a result which is reported in milligrams of potassium hydroxide equivalent per gram of sample (mg of KOH/g). Potentiometric titration for used oils (Test method BN A Document 2::: Henry Bickersteth, 1st Baron Langdale, PC (18 June 1783 – 18 April 1851), a member of the prominent Bickersteth family, was an English physician, law reformer, and Master of the Rolls. Early life and education Langdale was born on 18 June 1783 at Kirkby Lonsdale, the third son of Henry Bickersteth, a surgeon, and Elizabeth Batty. His younger brother was Rev. Edward Bickersteth, whose son Edward Henry became Bishop of Exeter and whose grandson Edward was Bishop of South Tokyo. By the advice of his uncle, Dr. Robert Batty, in October 1801, he went to Edinburgh to pursue his medical studies, and in the following year was called home to take his father's practice in his temporary absence. Disliking the idea of settling down in the country as a general practitioner, young Bickersteth determined to become a London physician. With a view to obtaining a medical degree, on 22 June 1802 his name was entered in the books of Gonville and Caius College, Cambridge, and, on 27 October in the same year, he was elected a scholar on the Hewitt foundation. Owing to his intense application to work, his health broke down after his first term. Career A change of scene being deemed necessary to insure his recovery, he obtained, through Dr. Batty, the post of medical attendant to Edward, fifth earl of Oxford, who was then on a tour in Italy. After his return from the continent he continued with the Earl of Oxford until 1805, when he returned to Cambridge. At this time he wanted to enter the army, but his parents disapproved. After three years he was senior Smith's mathematical prizeman of his year (1808), Miles Bland, Charles James Blomfield and Adam Sedgwick being among the competitors. He graduated senior wrangler from Gonville and Caius College, Cambridge in 1808 and after training as a physician like his father, he turned to law. Having taken his degree, Bickersteth was immediately elected a fellow of his college, and thereupon made up his mind to enter the profession of the law. Document 3::: In statistics, a dual-flashlight plot is a type of scatter-plot in which the standardized mean of a contrast variable (SMCV) is plotted against the mean of a contrast variable representing a comparison of interest . The commonly used dual-flashlight plot is for the difference between two groups in high-throughput experiments such as microarrays and high-throughput screening studies, in which we plot the SSMD versus average log fold-change on the y- and x-axes, respectively, for all genes or compounds (such as siRNAs or small molecules) investigated in an experiment. As a whole, the points in a dual-flashlight plot look like the beams of a flashlight with two heads, hence the name dual-flashlight plot. With the dual-flashlight plot, we can see how the genes or compounds are distributed into each category in effect sizes, as shown in the figure. Meanwhile, we can also see the average fold-change for each gene or compound. The dual-flashlight plot is similar to the volcano plot. In a volcano plot, the p-value (or q-value), instead of SMCV or SSMD, is plotted against average fold-change . The advantage of using SMCV over p-value (or q-value) is that, if there exist any non-zero true effects for a gene or compound, the estimated SMCV goes to its population value whereas the p-value (or q-value) for testing no mean difference (or zero contrast mean) goes to zero when the sample size increases . Hence, the value of SMCV is comparable whereas the value of p-value or q-value is not comparable in experiments with different sample size, especially when many investigated genes or compounds do not have exactly zero effects. The dual-flashlight plot bears the same advantage that the SMCV has, as compared to the volcano plot. See also Effect size SSMD SMCV Contrast variable ANOVA Volcano plot (statistics) Further reading Zhang XHD (2011) "Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-scale RNAi Research, Cambridge Uni The following are multiple choice questions (with answers) about knowledge and skills in advanced master-level STEM courses. What is the genus of the Bean leafroll virus (BLRV)? A. Luteovirus B. Retrovirus C. Adenovirus D. Picornavirus Answer:
A. Luteovirus
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