All of the following statements regarding streptokinase are true Except
Streptokinase is a 47-kDa protein produced by beta-hemolytic streptococci. It forms a stable complex with plasminogen, which is not inhibited by antiplasmin. A large loading dose is given intravenously to overcome antibodies that may be formed from prior streptococcal infections. Being a foreign protein it may rarely cause anaphylaxis.