What is the mechanism by which Phenoparbitons and Metalloporphysin act respectively to reduce bilirubin levels in neonatal jaundice
Phenobarbitone:
It induces UDP Glucuromyltransferase
↓
Increase Bilirubin conjugation
Metalloporphyrins:
It is competitive inhibitor of hence oxygenase, which converts hence to bilirubin.