All the following about drug induced SLE are true except
Ans. (a) More common in females(Ref: Robbins 9th/pg 218; 8th/pg 213)Drug-Induced LupusIt is a syndrome of positive ANA associated with symptoms such as fever, malaise, arthritis or intense arthralgias/myalgias, serositis, and/or rash.It appears during therapy with certain medications like antiarrhythmics procainamide, disopyramide, and propafenone; antihypertensive hydralazine; antithyroid propylthiouracil; antipsychotics chlorpromazine and lithium; anticonvulsants carbamazepine and phenytoin; antibiotics isoniazid, minocycline & nitrofurantoin; antirheumatic sulfasalazine; diuretic hydrochlorothiazide;It is predominant in whites & has less female predilection than SLEIt rarely involves kidneys or brain, is rarely associated with anti-dsDNA, is commonly associated with antibodies to histonesIt usually resolves over several weeks after discontinuation of the offending medication.