All of the following statements about Penicillin Binding Proteins (PBPs) are true, EXCEPT:
Penicillin Binding Proteins (PBP) catalyse an impoant step in bacterial cell wall synthesis i.e transpeptidase reaction which remove a terminal alanine in a cross linking reaction with a nearby peptide. It act as carboxy peptidase and transpeptidase. They are found in the cell membranel. Penicillin bind to this protein and inhibit its activity. Ref: Textbook of Pulmonary Medicine By D. Behera, Page 248, 252; Lippincott's Pharmacology, 4th Edition, Page 360.