Which of the following statement best describes the mechanism of action of insulin on target cells
Ref-Goodman and Gilman 12/e p1241) Enzymatic Receptors have two sites, the drug binds on the extracellular site and the intracellular site has enaymatic activity (mostly tyrosine kinase) This enzyme can be activated AK-STAT pathway. Insulin, growthormone, prolactin and cvtokines act enrvmatic receptors.