Albumin appearing in urine will be due to-
The molecular diameter of the plasma protein albumin is only about 6 nanometers, whereas the pores of the glomerular membrane are thought to be about 8 nanometers (80 angstroms). Albumin is restricted from filtration, however, because of its negative charge and the electrostatic repulsion exeed by negative charges of the glomerular capillary wall proteoglycans.