All of the following are advantages of transdermal drug delivery systems except
Ref-KDT 6/e p9 Transdermal route ts emploved for highly liid soluble drugs that can tra verse intact skin. The wize of the pores in tansdermal patch is adjusted to produce aunitorm and smouth absorption of the drug. This will thus, pro duce a delaved d smaller peak. in the plasma concentration. As the drug. is soins directly in the blood stream, tirst pass metabolism is avoided.