All of the following statements regarding apoptosis are TRUE, EXCEPT:
Apoptosis refers to preprogrammed natural or physiological cell death. It occurs without any inflammatory reaction. Features of apoptosis are: Death occur by shrinkage It affects isolated cells It is a gene initiated process, and DNA fragments are small and regular Histologic features: Cell shrinkage Nuclear condensation and fragmentation Membrane budding Buds includes cell organelles Buds detach to form apoptotic bodies Phagocytosis of the apoptotic bodies occur Ref: Textbook of Pathology By Datta page 48.