A chronic alcoholic have low energy production because of Thiamine deficiency as it is:
Ans. A. Acting as cofactor for alpha ketoglutarate Dehydrogenase and pyruvate dehydrogenase(Ref. Harper 31/e page 151-155)Alpha ketoglutarate dehydrogenase (TCA cycle) and PDH (link between aerobic glycolysis and TCA) require Thiamine, hence affect energy production, in alcoholic patients thiamin deficiency is present.