As per WHO 2010 guidelines, when should an HIV infected adult be staed on anti retroviral therapy?
Target population 2010 A guideline 2006 A guideline HIV+ asymptomatic ARV-naive individuals CD4 <=350 cells/mm3 CD4 <=200 cells/mm3 HIV+ symptomatic ARV-naive individuals WHO clinical stage 2 if CD4 <=350 cells/mm3 OR WHO clinical stage 3 or 4 irrespective of CD4 cell count WHO stage 2 or 3 and CD4 <=200 cells/mm3 WHO stage 3 if CD4 not available WHO stage 4 irrespective of CD4 cell count Consider treatment for WHO clinical stage 3 and CD4 cell count between 200 and 350 cells/mm3 HIV+ pregnant women CD4 <=350 cells/mm3 irrespective of clinical symptoms OR WHO clinical stage 3 or 4 irrespective of CD4 cell count WHO stage 1 or 2 and CD4 <=200 cells/mm3 WHO stage 3 and CD4 <=350 cells/ mm3 WHO stage 4 irrespective of CD4 count Ref: Epidemiology of communicable diseases Park's textbook of Preventive and Social Medicine, 21stedition, page-327.