A patient, Hari has been diagnosed to have schizophrenia. Which of the following acts as a limiting factor in the use of clozapine as an antipsychotic drug in this patient?
-Major adverse effects of clozapine are agranulocytosis and seizures. -High risk of causing lipodystrophy syndrome. -Does not prominently block dopamine receptors --> Negligible risk of extrapyramidal symptoms or hyperprolactinemia Effective against both positive and negative symptoms of schizophrenia.