An 18-year-old man who is known to have non penicillinase producing gonococcal urethritis is given an injection of penicillin and probenecid. What is the mechanism used by probenecid that makes penicillin more efficacious
Probenecid decreases the renal excretion of penicillin, thereby increasing both the half-life and the serum level. Ref:- KD Tripathi