All are true regarding Toxoplasmosis, except -
Toxoplasmosis Transmission increases from 1st to 3rd trimester Severity decreases from 1st to 3rd trimester Option 1 Toxoplasmosis in Adult - Mostly asymptomatic Option 2 Congenital toxoplasmosis: 1st Trimester: More severe infection 3rd Trimester: More chance of transmission If Mother is previously infected: Fetus is asymptomatic. Incidence: Approximately 1 per 1000 live bihs. Featured by: 3C + 2M (chorioretinitis, cerebral calcification, convulsion, microcephaly and mental retardation) Most common manifestation: Chorioretinitis Option 3 Congenital toxoplasmosis Diagnosis: IgM detection in fetal blood, IgA can also be used. Toxoplasma Ag in amniotic fluid, PCR to detect Toxoplasma genes. Option 4 Congenital infection occurring in 1st trimester of pregnancy may cause aboion and still bih, but when acquired late in pregnancy, it may produce retinitis and mental defects.(less severe)