A 32-year-old man has a mild anemia diagnosed on routine testing. He has no symptoms and feels fine. His clinical examination is normal, and a blood film reveals some target cells with some red cells having intraerythrocytic crystals.For the above patient with a hemoglobin abnormality, select the most likely diagnosis.
The patients with homozygous HbC disease have mild hemolysis, splenomegaly, target cells, and HbC crystals. Unlike sickle cell disease, the prognosis is favorable.