All of the following are major criteria for diagnosing Myeloma except?
Major criteria for diagnosing myeloma includes presence of plasmacytoma on tissue biopsy, bone marrow plasmacytosis (more than 30%), and serum electrophoresis showing monoclonal immunoglobulin spike. Presence of lytic bone lesions is a minor criteria for diagnosing myeloma. Ref: The Washingtom Manual Of Surgical Pathology: Depament Of Pathology , By Peter A Humphrey, Loius P.Dehner, Ohn D. Pfeifer, Page 565.