The diuretic group that does not require access to the tubular lumen to induce diuresis is ?
Ans. is 'c' i.e. Mineralocoicoid antagonist Spirinolactone is mineralocoicoid (aldosterone) antagonist. It opposes the action of Aldosterone without requiring access to the tubular lumen. Spirinolactone (as well as aldosterone) act from the interstitial side.