output
stringclasses
3 values
instruction
stringclasses
1 value
input
stringlengths
12
885
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Awareness of hypertension was based on self-report.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
We evaluated the clinical characteristics and surgical outcomes of 23 patients with NTM lung diseases who had underwent pulmonary resection.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
In mouse models, we found that metastasis of GC-A-nonexpressing tumor cells (i.e., B16 mouse melanoma cells) to the lung was increased in vascular endothelium-specific GC-A knockout mice and decreased in vascular endothelium-specific GC-A transgenic mice compared with control mice.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Despite these efforts, fruit and vegetable consumption and physical activity did not change from baseline to post-test or differed significantly between intervention and wait list control groups.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
To date, the evidence of a reliable marker of prognosis in these cases remains scarce.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Several advantages of robotic surgery have been reported, but there is no comparative study on postoperative pain between the 2 techniques.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Ventral stabilisation yields more advantages than dorsal instrumentation in the long term.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Genome-wide methylation in peripheral blood lymphocytes of 376 healthy women from the prospective EPIC study was investigated using LUminometric Methylation Assay (LUMA).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
This excessive interference reflected a blurring of intra- rather than inter-category distinctions as if the acuity of word-object associations had been diminished so that correspondences were easier to recognize at generic than specific levels.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Ankle-brachial indices were abnormal in 78% of patients.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
However, there is an urgent need for noninvasive and sensitive biomarkers for prediction of PIR.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Mitotic regulatory pathways insure proper timing of mitotic entry, sister chromatid cohesion and separation, and cytokinesis.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
GRS63 was associated with BMD (‚âÖ3% of the variation explained) but not with BMD change.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
This study examines prospectively the randomised, long-term, clinical and radiological results of the treatment of spondylitis patients by ventro-dorsal or ventral spine fusion.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Least absolute shrinkage and selection operator (Lasso) and multiple logistic regression were performed to identify risk factors of disease.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The paired Student t test was used to evaluate differences in diameters of the ostium of the CS in anteroposterior and superoinferior direction.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
TNF-induced albuminuria was aggravated in mice with podocyte-specific ABCA1 deficiency and was partially prevented by cholesterol depletion with cyclodextrin.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
This event requires BIM CpG methylation/demethylation with 5-azacytidine that leads to detachment of the MeCP2 corepressor complex and reacetylation of the histone tails.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
BIM silencing occurs through recruitment of MeCP2 and the SIN3a/histone deacetylase 1/2 (HDAC1/2) corepressor complex.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Traits such as non-acceptance of emotions, lack of clarity and lack of awareness of emotions were related to increased social anxiety; while acting with awareness, non-reactivity, and better ability to describe emotions was related to decreased social anxiety.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The data demonstrate that, along with peripheral vascular occlusive disease, accelerated vascular stiffening is an early and pervasive mechanism of vascular disease in Hutchinson-Gilford progeria syndrome.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Based on their reported frequencies and effect sizes (OR‚â•25), we had sufficient statistical power to detect the large majority (80%) of genuine associations at these loci.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Poor compliance for follow-up with formal vision examination limited our ability to confirm these abnormalities.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
However, all factors examined were associated with at least one QoL domain.
This is a weak advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Although it is associated with a relatively high complication rate, patients with NTM lung disease whose disease is localized to one lung and who can tolerate resectional surgery might be considered for surgery, if there has been poor response to drug therapy or if the patients develop significant disease-related complications such as hemoptysis.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Health promotion in transport industry workplaces should be an important topic for future research.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The study aims to examine the relationship between beliefs about medicines and self-medication with analgesics in dental pain management in Malaysia.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
In 3 (5.7%) cases, conversion was required.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Only 4.7% (2674 of 57\u2009170) received HCV screening, with strongest predictors being nonpsychiatric health care utilization and comorbid substance abuse.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
This study showed the association between stroke and sleep habits in the southern Chinese population and might help in better detecting important sleep-related factors for stroke risk.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
We conducted a pilot randomized controlled trial to determine the feasibility and acceptability of a patient navigation intervention.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The association of MCP-1 -2518 A/G SNP with SSc observed originally in German population was not replicated in the Slovak population.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
In gene-level analyses, CDC25C, SCC1/RAD21, TLK2, and SMC6L1 were associated (P\xa0<\xa00.05) with overall breast cancer risk, CDC6, CDC27, SUMO3, RASSF1, KIF2, and CDC14A were associated with high grade breast cancer risk, and EIF3S10 and CDC25A were associated with both.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
We sought to assess the safety and immunological changes of using a biologically standardized and modified Parietaria judaica pollen extract in accelerated schedules.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated by unconditional logistic regression adjusted for confounders.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
We set the fraction of inspired oxygen (FiO2) at 0.30.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
From 127 whole-genome-sequenced isolates, we reconstructed an evolutionary framework of E.\xa0coli ST410 which portrays the antimicrobial-resistant clades B2/H24R, B3/H24Rx, and B4/H24RxC.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The overall adjusted odds ratio for BP control in the intervention versus usual care group was 3.64 (P\xa0<\xa0.001).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Sixty consecutive patients undergoing elective open-heart surgery were prospectively enrolled in a study to compare the efficacy of 3 different antifibrinolytic drugs to reduce postoperative bleeding and to reduce homologous blood requirements in combination with blood-saving techniques and restrictive indications for blood transfusion.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Background and purpose - Criticism of the lateral approach (LA) for hip arthroplasty is mainly based on the risk of poor patient-reported outcomes compared to the posterior approach (PA).
This is a strong advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
These results suggest that the LOS test is an informative tool that should be included in any objective balance evaluations that screen TBI patients with balance complaints.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
However, these participants had weaker beliefs in General-Harm (12.00 vs. 10.29, p = 0.006) and General-Overuse (11.38 vs. 10.31, p = 0.032) than those not practising self-medication.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
As primary endpoint we investigated the incidence of CIN (increase of serum creatinine ‚â•0.5‚Äämg/dL and/or ‚â•25% within 48‚Ääh of CM).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Although the AD-associated genetic variants appear to have small effects on early cognitive change, replication will be required to establish whether there is a discernible influence on cognitive status in midlife.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
RTX induced initial B cell depletion (<5 cells/μL) in all patients but re-population was observed in 3 patients.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Possible vision abnormalities were found in 11 of the 137 children (8%).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Significant increases in allergen-specific IgG4 and IgG against P. judaica extract and rPar j 2 and significant decrease of specific IgE against Par j 2 were observed.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Of a total of 115 registered patients having solitary hepatocellular carcinoma (HCC) 2 to 5 cm in diameter, 18 (15.7%) were excluded after randomization.
This is a weak advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
CD133+ CD44+ CD54+ cellular subpopulation of CTCs has a prognostic value in CRC patients with liver metastasis, especially in the survival of CRC patients with liver metastasis who did not undergo surgical treatment for metastasis.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Over 63% consumed at least one serve of unhealthy foods per day, and 65% drank at least one can of sugary drink per day.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The original GWAS melanoma study included 15 990 cases and 26 409 controls, representing the largest international meta-analysis of melanoma susceptibility.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Despite this, there is a paucity of data about Australian truck drivers' diet and physical activity behaviors.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Results: Dental arch measurements, including inter-canine and inter-molar distance, were found to be significantly greater in males than females (p less than\xa00.05).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
EIT-guided PEEP titration led to a more dorsal shift of ventilation.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Consistent with other international studies, participants living in neighborhoods with a mix of land uses and a transit stop within a 10-minute walk from home were more likely to use active commuting (both p < 0.01).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Pain treatment increased progressively in complexity.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Unipolar major depression is often a chronic disease that may require lifelong prophylaxis.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Participants were classified according to the socioeconomic status of their households, defined by the Oxford Poverty and Human Development Initiative's multidimensional poverty index (MPI).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
ANP is known to bind specifically to NPR1 [also called guanylyl cyclase-A (GC-A) receptor].
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
BIM is a proapoptotic member of the Bcl-2 family.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Here we demonstrate that cancer recurrence after curative surgery was significantly lower in ANP-treated patients than in control patients (surgery alone).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
According to the interval between hysterectomy and cervical conization, patients were classified into 1-2-week, 4-5-week, and 6-week groups.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Of these patients, 14 had benign masses and 7 had malignant tumors.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
However, only one obesity association was replicated.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Hand-held, portable, instrument-based vision screening devices can be used in children as young as 6 months of age.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The study was a cross-sectional, non-randomized study in public health.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The diameter of the CS ostium in the superoinferior direction (1.13\xa0±\xa00.26\xa0cm) was larger than in the anteroposterior direction (0.82\xa0±\xa00.19\xa0cm) (P\xa0<\xa00.05).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
To begin development of methods that allow this, we used videofluorography to record the deglutition behaviors of 22 Fisher 344/Brown Norway rats in young adult (9 months old), old (32 months old), and parkinsonian (unilateral lesion to the medial forebrain bundle) groups.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Materials and Methods In this prospective study, pregnant women were recruited and their healthy full-term newborns underwent a brain MRI including diffusion tensor imaging at approximately 2 weeks of age.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The purpose of this study was to assess social anxiety, and identify how social support, emotion regulation and mindfulness uniquely contribute to social anxiety among adolescents in Birgunj, Nepal.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
This strategy provided baseline measures of participant stature, s.c. body fat, and humoral and cell-mediated immune activity as well as subsample longitudinal measures of linear growth (1 wk, 3 mo, 20 mo) and acute inflammation.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
These dissociations between verbal and non-verbal markers of object knowledge indicate that the reduced neural mass at peak atrophy sites of the left temporal tip, accounting for half or more of the presumed premorbid volume, was unlikely to have contained domain-independent semantic representations of the type that would be expected in a strictly amodal hub.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The ARR is associated with chronic kidney disease (CKD), renal artery stenosis, renin adenoma.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
We expected that prayer would be related to pain tolerance in reducing the impact of the pain on patient's daily life, but not necessarily to pain severity.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Naming errors were attributed to pure retrieval failure if the object could not be named even when the denoting word was understood, the object recognized and the two accurately matched.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
In comparison, only 38 melanoma-related genes were identified in the original meta-analysis.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The etiology of primary antibody deficiencies is largely unknown.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
After 1:1 propensity score matching, the final analysis included 142 patients each in the LPN and RAPN groups.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Participants practising self-medication for dental pain reported more positive beliefs in General-Necessity (13.04 vs. 9.98, p = 0.001) than those not practising self-medication.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
A cross-sectional questionnaire design was adopted in order to measure demographics, prayer, pain outcomes (i.e., pain severity and pain tolerance), and cognitive positive re-appraisal.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
No other associations with HLA genotype were identified.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Between January 1987 and December 1998, we treated 867 patients suffering from primary solid malignant tumours.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Similar trend was shown among both boys and girls for their father's education level.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Our aim was to evaluate appearance of unrelated atypical serum immunofixation patterns (ASIPs) as a marker of prognosis in MM patients submitted to ASCT.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Methods: Patients referred for a stress-rest 99mTc-sestamibi protocol and positioned in the biker position, with the chest leaning forward on the D.SPECT camera-head at 35° from vertical, had an additional resting D.SPECT recording in the supine position (n = 40) or in the sitting position with the back rearward at 30° from vertical (n = 40).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Pulmonary dysfunction is a significant contributor to morbidity and mortality in the pediatric burned population.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Continuous infusion of remifentanil during general anesthesia can cause higher intensity of postoperative pain and more frequent itching than general anesthesia without remifentanil infusion immediately after thyroidectomy.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Different environmental attributes were associated with active commuting, suggesting that these relationships are complex and may distinctly differ from those in high-income countries.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Hemoconcentration and reinfusion of blood drained from the operative field and the extracorporeal circuit after operation were used in all patients.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Policies and investments to promote active commuting remain under-developed in LMICs like India, which grapples with traffic congestion, lack of activity-supportive infrastructure, poor enforcement of traffic rules and regulations, air pollution, and overcrowding.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
One hundred fifty patients underwent 151 limb-salvage surgeries for bone cancer of the extremities in this series.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
The purpose of our study was to assess quality of life (QoL) among Georgian HIV-infected individuals and to examine factors associated with QoL.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
In 3 polymorphisms of AKT1 (rs1130214, rs2494732, rs3803300), the GT/TT genotype of rs1130214 in cases and controls had a significant frequency difference (P\u200a=\u200a.04) and was 1.71 times risk developing CHD, compared with AA (OR\u200a=\u200a1.71, 95%CI\u200a=\u200a1.02-2.86), and T allele had 1.63 times risk for carriers (OR\u200a=\u200a1.63, 95%CI\u200a=\u200a1.05-2.54).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
These correlations were largely independent of several demographic parameters as well as family environment.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
These infants were tested at approximately 2 years of age with the Bayley Scales of Infant Development (BSID).
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
We describe a project that followed all of these recommended strategies, but did not achieve desired outcomes.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Eleven of 69 prospectively enrolled primary progressive aphasics were selected for this study because of peak atrophy sites located predominantly or exclusively within the anterior left temporal lobe.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
This represented 3% to 48% of all AML searches (median 20%) per center, totaling 3 to 172 patients (median 22) per center.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Aldosterone-to-renin ratio (ARR) is a screening test for primary aldosteronism, but it was impacted by a bunch of clinical covariates.
This is no advice
Question: is this a 2) strong advice, 1) weak advice 0) no advice?
Donor KIR genotype was reported at a median of 14 days after request (≤26 days for 76% of searches).