I have to give my eager vote for rumpy pumpy as well (from the pumpers perspective), but as for the various ideas here, I would much prefer setting where difference to world as we know it - if any is rather simple. I think that it is even more important in potentially large group game than in one on one. Something like Corvus's idea could work, but quite honestly any rather isolated setting in even very ordinary world would. I hate high school RP:s and most likely would not be in one, but good thing about game happening generally in one location offering various sub environments (classrooms, gym, nurses office etc. in school setting) gives very nice, solid frame in which to work.<br/><br/>Something like Corvus's idea would work great in scenario where what ever event wiped people out left most of the infrastructure and such intact. Sadly, I think that any near extinctuous event would be the death of most of the large cities as well. If 99% of the population suddenly dies, a lot of appliances will be left on without supervision, and small fires growing to large, and other such incidents would make big cities burn like wildfire. Generally I think it would be more enjoyable if majority of the attraction of the story came from within characters instead of the setting.<br/><br/>