It has a few small similarities and a few small differences(like how Nina ends her encounter with Scar), but it also has major differences as Brotherhood follows the manga nearly to the letter, while FMA went off and did it's own thing a majority of the time. Like Sloth being Ed and Al's mom and having water powers. In Brotherhood, Sloth is a huge guy(bigger than Armstrong) and the fastest Homunculus which is ironic because he's lazy as fuck.<br/><br/>Wrath isn't a little kid who got Ed's body parts, etc, etc...<br/><br/>