I remembered how some of the masters work in the criminal underworld.  With this in mind, and given the blessing of the GM, I had an idea for some 2035 drugs which might exist.<br/><br/>These would have about a 70% effectiveness rate, with 30% of the populace being naturally resistant or immune for one reason or another.  This means that if a slave's player didn't want drugs to work, they just wouldn't, and offers a good reason for their ineffectiveness.<br/><br/>The first is Pink Flower, an herbal aphrodisiac.<br/><br/>The second is Bunraku (Japanese for Puppet), which is more designed to numb and calm down slaves, allowing them to continue to work long after a normal body would be exhausted and keep them from passing out.<br/><br/>Strangely, unlike conventional illicit substances, the effects of both Pink Flower and Bunraku end up permanent to some degree when repeatedly given to a slave.<br/><br/>I'll leave it up to the GM if these should be canon or not.