You could probably make it just Large... the "Five stories of a skyscraper" sample base is that size, and an entire skyscraper could be a bit excessive (and hard to find in San Francisco, the rents are astronomical there).  So it could be on top of a skyscraper with normal tenants, or just a five story building in the city.<br/><br/>Leaning more towards the Super MILF now.  She'd have twin daughters attending a Bay Area university as a complication and hook for other PCs to know her.  They definitely don't have super powers and certainly haven't been hiding them from their mom.  Twincest is a possibility too. :)