You could attempt such an action on the lock.  The lock, being reinforced, has 75 hit points, while the door it's mounted in probably has 20 hit points.  (though it could be reinforced from the back and have up to 50 hit points)  After taking more than 10 points of damage, the lock will fuse shut and be impossible to pick.  The door can also be opened with a DC 25 strength check to pull it out of the surrounding dungeon walls.