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\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline & \textbf{Weak} & & & \multicolumn{2}{c|}{\textbf{\textbf{S}B}} & \multicolumn{2}{c|}{\textbf{BH}} & \multicolumn{2}{c|}{\textbf{\textbf{S}GoF}} \\ \hline \textbf{N} & \textbf{\% effect} & \textbf{S} & \textbf{S}ignificant & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} \\ \hline 5 & 5\% & 100 & 5.2 & 0.04 & 98 & 0.04 & 98 & 0.07 & 85 \\ \hline 5 & 5\% & 1000 & 5.2 & 0.01 & 78 & 0.01 & 80 & 0.01 & 91 \\ \hline 5 & 5\% & 10000 & 5.2 & 0.00 & 91 & 0.00 & 88 & 0.02 & 89 \\ \hline 5 & 10\% & 100 & 5.4 & 0.06 & 86 & 0.06 & 87 & 0.09 & 83 \\ \hline 5 & 10\% & 1000 & 5.5 & 0.01 & 83 & 0.01 & 84 & 0.04 & 78 \\ \hline 5 & 10\% & 10000 & 5.5 & 0.00 & 80 & 0.00 & 83 & 0.11 & 80 \\ \hline 5 & 20\% & 100 & 5.9 & 0.08 & 57 & 0.08 & 60 & 0.12 & 64 \\ \hline 5 & 20\% & 1000 & 6.0 & 0.01 & 57 & 0.01 & 58 & 0.13 & 63 \\ \hline \multirow{3}{*}{5} & 20\% & 10000 & 6.0 & 0.00 & 70 & 0.00 & 69 & 0.54 & 63 \\ \hline & & Mean & 0.02 & 77.8 & 0.02 & 78.6 & 0.12 & 77.3 \\ \hline & & \textbf{S}D & 0.030 & 14.18 & 0.030 & 13.45 & 0.161 & 11.24 \\ \hline 10 & 5\% & 100 & 5.7 & 0.05 & 72 & 0.06 & 70 & 0.09 & 80 \\ \hline 10 & 5\% & 1000 & 5.6 & 0.01 & 69 & 0.01 & 67 & 0.06 & 77 \\ \hline 10 & 5\% & 10000 & 5.6 & 0.00 & 71 & 0.00 & 71 & 0.22 & 74 \\ \hline 10 & 10\% & 100 & 6.2 & 0.06 & 56 & 0.08 & 57 & 0.19 & 67 \\ \hline 10 & 10\% & 1000 & 6.2 & 0.01 & 44 & 0.01 & 47 & 0.24 & 59 \\ \hline 10 & 10\% & 10000 & 6.3 & 0.00 & 44 & 0.00 & 45 & 0.84 & 61 \\ \hline 10 & 20\% & 100 & 7.6 & 0.12 & 35 & 0.15 & 35 & 0.52 & 42 \\ \hline 10 & 20\% & 1000 & 7.5 & 0.01 & 30 & 0.02 & 30 & 1.14 & 42 \\ \hline \multirow{3}{*}{10} & 20\% & 10000 & 7.5 & 0.00 & 27 & 0.00 & 30 & 2.11 & 44 \\ \hline & & Mean & 0.03 & 49.8 & 0.04 & 50.2 & 0.60 & 60.7 \\ \hline & & \textbf{S}D & 0.041 & 17.85 & 0.051 & 16.72 & 0.674 & 15.15 \\ \hline 20 & 5\% & 100 & 6.4 & 0.14 & 33 & 0.17 & 35 & 0.20 & 60 \\ \hline 20 & 5\% & 1000 & 6.5 & 0.02 & 31 & 0.03 & 30 & 0.33 & 51 \\ \hline 20 & 5\% & 10000 & 6.4 & 0.00 & 18 & 0.00 & 19 & 1.01 & 53 \\ \hline 20 & 10\% & 100 & 7.8 & 0.24 & 17 & 0.32 & 18 & 0.61 & 38 \\ \hline 20 & 10\% & 1000 & 7.9 & 0.03 & 13 & 0.06 & 16 & 1.53 & 36 \\ \hline 20 & 10\% & 10000 & 7.9 & 0.01 & 7 & 0.01 & 10 & 2.46 & 40 \\ \hline 20 & 20\% & 100 & 10.7 & 0.36 & 8 & 0.57 & 10 & 2.24 & 24 \\ \hline 20 & 20\% & 1000 & 10.8 & 0.06 & 6 & 0.15 & 9 & 4.38 & 25 \\ \hline \multirow{3}{*}{20} & 20\% & 10000 & 10.8 & 0.01 & 4 & 0.04 & 6 & 5.35 & 27 \\ \hline & & Mean & 0.10 & 15.22 & 0.15 & 17 & 2.01 & 39.3 \\ \hline & & \textbf{S}D & 0.126 & 10.67 & 0.188 & 9.89 & 1.81 & 13.02 \\ \hline \end{tabular} \end{table}
PMC2719628_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline & \textbf{Weak} & & & \multicolumn{2}{c|}{\textbf{\textbf{S}B}} & \multicolumn{2}{c|}{\textbf{BH}} & \multicolumn{2}{c|}{\textbf{\textbf{S}GoF}} \\ \hline \textbf{N} & \textbf{\% effect} & \textbf{S} & \textbf{S}ignificant & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} \\ \hline 20 & 5\% & 100 & 5.7 & 0.10 & 73 & 0.10 & 72 & 0.10 & 77 \\ \hline 20 & 5\% & 1000 & 5.7 & 0.01 & 53 & 0.01 & 57 & 0.07 & 78 \\ \hline 20 & 5\% & 10000 & 5.7 & 0.00 & 65 & 0.00 & 61 & 0.25 & 55 \\ \hline 20 & 10\% & 100 & 6.2 & 0.07 & 51 & 0.08 & 51 & 0.18 & 68 \\ \hline 20 & 10\% & 1000 & 6.1 & 0.01 & 41 & 0.01 & 40 & 0.19 & 56 \\ \hline 20 & 10\% & 10000 & 6.1 & 0.00 & 40 & 0.00 & 33 & 0.68 & 33 \\ \hline 20 & 20\% & 100 & 6.8 & 0.14 & 39 & 0.16 & 38 & 0.30 & 52 \\ \hline 20 & 20\% & 1000 & 7.0 & 0.01 & 24 & 0.01 & 25 & 0.70 & 35 \\ \hline \multirow{3}{*}{20} & 20\% & 10000 & 7.0 & 0.00 & 16 & 0.00 & 16 & 1.58 & 19 \\ \hline & & Mean & 0.04 & 44.7 & 0.04 & 43.7 & 0.45 & 52.6 \\ \hline & & \textbf{S}D & 0.052 & 18.17 & 0.058 & 18.06 & 0.482 & 20.37 \\ \hline 40 & 5\% & 100 & 6.0 & 0.14 & 45 & 0.15 & 46 & 0.13 & 69 \\ \hline 40 & 5\% & 1000 & 6.0 & 0.02 & 31 & 0.02 & 33 & 0.15 & 57 \\ \hline 40 & 5\% & 10000 & 6.0 & 0.00 & 22 & 0.01 & 23 & 0.61 & 37 \\ \hline 40 & 10\% & 100 & 7.0 & 0.21 & 26 & 0.25 & 28 & 0.33 & 51 \\ \hline 40 & 10\% & 1000 & 7.0 & 0.03 & 18 & 0.04 & 20 & 0.71 & 38 \\ \hline 40 & 10\% & 10000 & 7.0 & 0.01 & 12 & 0.01 & 14 & 1.56 & 17 \\ \hline 40 & 20\% & 100 & 8.9 & 0.34 & 20 & 0.45 & 21 & 1.02 & 32 \\ \hline 40 & 20\% & 1000 & 8.9 & 0.05 & 8 & 0.10 & 9 & 2.50 & 21 \\ \hline \multirow{3}{*}{40} & 20\% & 10000 & 8.9 & 0.01 & 5 & 0.04 & 7 & 3.44 & 6 \\ \hline & & Mean & 0.09 & 20.8 & 0.12 & 22.3 & 1.16 & 36.4 \\ \hline & & \textbf{S}D & 0.117 & 12.34 & 0.148 & 12.23 & 1.143 & 20.19 \\ \hline \end{tabular} \end{table}
PMC2719628_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline & \textbf{\textbf{S}trong} & & & \multicolumn{2}{c|}{\textbf{\textbf{S}B}} & \multicolumn{2}{c|}{\textbf{BH}} & \multicolumn{2}{c|}{\textbf{\textbf{S}GoF}} \\ \hline \textbf{N} & \textbf{\% effect} & \textbf{S} & \textbf{S}ignificant & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} \\ \hline 5 & 5\% & 100 & 6.6 & 0.09 & 62 & 0.11 & 62 & 0.23 & 59 \\ \hline 5 & 5\% & 1000 & 6.7 & 0.01 & 53 & 0.01 & 54 & 0.47 & 60 \\ \hline 5 & 5\% & 10000 & 6.7 & 0.00 & 42 & 0.00 & 47 & 1.24 & 60 \\ \hline 5 & 10\% & 100 & 8.5 & 0.14 & 31 & 0.17 & 30 & 0.85 & 46 \\ \hline 5 & 10\% & 1000 & 8.4 & 0.01 & 36 & 0.02 & 35 & 1.97 & 43 \\ \hline 5 & 10\% & 10000 & 8.3 & 0.00 & 31 & 0.00 & 30 & 2.88 & 45 \\ \hline 5 & 20\% & 100 & 11.7 & 0.17 & 18 & 0.28 & 18 & 3.03 & 26 \\ \hline 5 & 20\% & 1000 & 11.7 & 0.02 & 17 & 0.03 & 18 & 5.28 & 28 \\ \hline \multirow{3}{*}{5} & 20\% & 10000 & 11.7 & 0.00 & 22 & 0.00 & 21 & 6.23 & 29 \\ \hline & & Mean & 0.05 & 34.7 & 0.07 & 35 & 2.46 & 44 \\ \hline & & \textbf{S}D & 0.067 & 15.48 & 0.099 & 16.04 & 2.118 & 13.91 \\ \hline 10 & 5\% & 100 & 8.7 & 0.49 & 8 & 0.75 & 11 & 0.95 & 24 \\ \hline 10 & 5\% & 1000 & 8.6 & 0.09 & 6 & 0.27 & 8 & 2.25 & 23 \\ \hline 10 & 5\% & 10000 & 8.6 & 0.01 & 4 & 0.11 & 6 & 3.21 & 28 \\ \hline 10 & 10\% & 100 & 12.3 & 1.00 & 5 & 2.08 & 8 & 3.56 & 14 \\ \hline 10 & 10\% & 1000 & 12.3 & 0.18 & 2 & 1.18 & 6 & 5.92 & 17 \\ \hline 10 & 10\% & 10000 & 12.3 & 0.03 & 2 & 0.93 & 5 & 6.86 & 20 \\ \hline 10 & 20\% & 100 & 19.5 & 1.91 & 3 & 6.37 & 5 & 10.53 & 9 \\ \hline 10 & 20\% & 1000 & 19.6 & 0.33 & 1 & 5.38 & 4 & 13.23 & 11 \\ \hline \multirow{3}{*}{10} & 20\% & 10000 & 19.6 & 0.05 & 1 & 5.30 & 4 & 14.17 & 12 \\ \hline & & Mean & 0.45 & 3.6 & 2.49 & 6.3 & 6.74 & 17.6 \\ \hline & & \textbf{S}D & 0.631 & 2.40 & 2.481 & 2.29 & 4.856 & 6.58 \\ \hline 20 & 5\% & 100 & 9.8 & 2.92 & 2 & 4.18 & 7 & 1.59 & 6 \\ \hline 20 & 5\% & 1000 & 9.7 & 1.38 & 0 & 4.04 & 5 & 3.35 & 4 \\ \hline 20 & 5\% & 10000 & 9.7 & 0.47 & 0 & 3.97 & 5 & 4.24 & 6 \\ \hline 20 & 10\% & 100 & 14.4 & 5.86 & 1 & 9.06 & 5 & 5.49 & 2 \\ \hline 20 & 10\% & 1000 & 14.3 & 2.75 & 0 & 8.90 & 5 & 7.93 & 3 \\ \hline 20 & 10\% & 10000 & 14.3 & 0.95 & 0 & 8.85 & 4 & 8.90 & 5 \\ \hline 20 & 20\% & 100 & 23.6 & 11.78 & 0 & 19.04 & 4 & 14.64 & 2 \\ \hline 20 & 20\% & 1000 & 23.6 & 5.50 & 0 & 18.88 & 4 & 17.23 & 2 \\ \hline \multirow{3}{*}{20} & 20\% & 10000 & 23.7 & 1.91 & 0 & 19.01 & 4 & 18.27 & 3 \\ \hline & & Mean & 3.72 & 0.3 & 10.66 & 4.7 & 9.07 & 3.7 \\ \hline & & \textbf{S}D & 3.558 & 0.71 & 6.586 & 0.97 & 6.209 & 1.66 \\ \hline \end{tabular} \end{table}
PMC2719628_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline & \textbf{\textbf{S}trong} & & & \multicolumn{2}{c|}{\textbf{\textbf{S}B}} & \multicolumn{2}{c|}{\textbf{BH}} & \multicolumn{2}{c|}{\textbf{\textbf{S}GoF}} \\ \hline \textbf{N} & \textbf{\% effect} & \textbf{S} & \textbf{S}ignificant & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} & \textbf{\textbf{\textbf{Detected}}} & \textbf{\textbf{\textbf{FDR}}} \\ \hline 20 & 5\% & 100 & 7.2 & 0.26 & 21 & 0.29 & 23 & 0.38 & 55 \\ \hline 20 & 5\% & 1000 & 7.1 & 0.04 & 8 & 0.05 & 10 & 0.77 & 34 \\ \hline 20 & 5\% & 10000 & 7.1 & 0.00 & 5 & 0.02 & 5 & 1.67 & 21 \\ \hline 20 & 10\% & 100 & 9.0 & 0.42 & 13 & 0.54 & 17 & 1.04 & 32 \\ \hline 20 & 10\% & 1000 & 9.0 & 0.07 & 3 & 0.15 & 7 & 2.58 & 20 \\ \hline 20 & 10\% & 10000 & 9.0 & 0.01 & 2 & 0.07 & 2 & 3.55 & 12 \\ \hline 20 & 20\% & 100 & 12.5 & 0.77 & 7 & 1.27 & 8 & 3.62 & 17 \\ \hline 20 & 20\% & 1000 & 12.7 & 0.13 & 2 & 0.65 & 3 & 6.29 & 10 \\ \hline \multirow{3}{*}{20} & 20\% & 10000 & 12.8 & 0.02 & 1 & 0.47 & 2 & 7.33 & 7 \\ \hline & & Mean & 0.19 & 6.9 & 0.39 & 8.6 & 3.03 & 23.1 \\ \hline & & \textbf{S}D & 0.258 & 6.51 & 0.402 & 7.20 & 2.45 & 15.09 \\ \hline 40 & 5\% & 100 & 8.4 & 1.05 & 7 & 1.36 & 12 & 0.67 & 26 \\ \hline 40 & 5\% & 1000 & 8.5 & 0.29 & 2 & 0.95 & 6 & 2.08 & 14 \\ \hline 40 & 5\% & 10000 & 8.5 & 0.11 & 1 & 0.92 & 2 & 3.03 & 6 \\ \hline 40 & 10\% & 100 & 11.8 & 1.98 & 3 & 3.12 & 7 & 2.90 & 12 \\ \hline 40 & 10\% & 1000 & 11.9 & 0.58 & 1 & 2.76 & 4 & 5.50 & 9 \\ \hline 40 & 10\% & 10000 & 11.8 & 0.21 & 0 & 2.83 & 1 & 6.42 & 2 \\ \hline 40 & 20\% & 100 & 18.7 & 3.76 & 1 & 8.13 & 5 & 9.67 & 7 \\ \hline 40 & 20\% & 1000 & 18.6 & 1.17 & 0 & 7.72 & 2 & 12.23 & 4 \\ \hline \multirow{3}{*}{40} & 20\% & 10000 & 18.6 & 0.42 & 0 & 7.62 & 0 & 13.18 & 1 \\ \hline & & Mean & 1.06 & 1.7 & 3.93 & 4.3 & 6.19 & 9 \\ \hline & & \textbf{S}D & 1.173 & 2.24 & 3.029 & 3.71 & 4.557 & 7.70 \\ \hline \end{tabular} \end{table}
PMC2719628_table_4
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline & \multicolumn{2}{c|}{\textbf{Null}} & \multicolumn{2}{c|}{\textbf{Weak}} & \multicolumn{2}{c|}{\textbf{Strong}} \\ \hline & \textbf{\textbf{\textbf{A}}} & \textbf{\textbf{\textbf{B}}} & \textbf{\textbf{\textbf{A}}} & \textbf{\textbf{\textbf{B}}} & \textbf{\textbf{\textbf{A}}} & \textbf{\textbf{\textbf{B}}} \\ \hline Pop 1 & 1 & 1 & 1 & 0.67 & 1 & 0.43 \\ \hline Pop 2 & 1 & 1 & 0.67 & 1 & 0.43 & 1 \\ \hline \end{tabular} \end{table}
PMC2719628_table_5
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|} \hline \textbf{Gene} & \textbf{chr} & \textbf{p53-RE Start} & \textbf{p53-RE End} & \textbf{p53-RE_Dimer 1} & \textbf{p53-RE_Spacer} & \textbf{p53-RE_Dimer 2} & \textbf{Spacer Length} & \textbf{Ref.} \\ \hline PLK2 & 5 & 57793857 & 57793877 & GGGCAAGTCC & & AGGCATGTTT & 0 & [11] \\ \hline PPM1J & 1 & 113048061 & 113048081 & GGGCTTGCTC & & AGGCATGTTC & 0 & [25] \\ \hline DDB2 & 11 & 47193105 & 47193126 & GAACAAGCCC & T & GGGCATGTTT & 1 & [11] \\ \hline KIAA1486 & 2 & 226209743 & 226209763 & GAACATGCCT & & GGGCTAGCCT & 0 & [11] \\ \hline MTHFD1L & 6 & 151220175 & 151220195 & GGACATGCCT & & GGGCATGTCC & 0 & [11] \\ \hline PRKAG2 & 7 & 151016282 & 151016302 & GAGCATGTCT & & GAACATGTTC & 0 & [11] \\ \hline AKAP6 & 14 & 31884451 & 31884471 & AGACATGTTT & & GGGCATGTCT & 0 & [25] \\ \hline BIRC8 & 19 & 58490331 & 58490351 & GGACATGCCT & & GGGCATGTCT & 0 & [25] \\ \hline APBB2 & 4 & 40721763 & 40721784 & AAACTTGTTT & C & AGGCTAGCCC & 1 & [26] \\ \hline TSHR & 14 & 80618516 & 80618537 & AAACTTGCTT & C & AAGCTAGCCC & 1 & [25] \\ \hline DMD & X & 31592231 & 31592252 & AAACATGCTC & T & GGACTAGCCT & 1 & [25] \\ \hline SLCO2B1 & 11 & 74540123 & 74540146 & GAGCAAGCCT & GGG & GGACATGTTC & 3 & [26] \\ \hline ATF3 & 1 & 210865885 & 210865908 & AGGCAAGTCC & TCA & GAGCATGTTT & 3 & [11] \\ \hline FRMD4A & 10 & 14167552 & 14167577 & AAGCTTGCTT & TCAGA & GGGCTTGCCT & 5 & [11] \\ \hline EGFR & 7 & 55176461 & 55176487 & AAACATGCCT & TTCAAA & GAACTAGTTC & 6 & [25] \\ \hline MMP2 & 16 & 54067700 & 54067729 & AGGCAAGTCC & ATAAAGTGA & AAGCAAGTTT & 9 & [11] \\ \hline KRT15 & 17 & 36930241 & 36930270 & GAACATGCCC & TGTGAGCCT & GAGCATGTTC & 9 & [25] \\ \hline DLG2 & 11 & 83032605 & 83032636 & GAACATGTCC & ATGGCTGTCTC & AGACTTGTTT & 11 & [25] \\ \hline NRXN3 & 14 & 78316130 & 78316162 & AGACTTGCCC & AACTAGACATCA & AGGCATGTTT & 12 & [25] \\ \hline FHIT & 3 & 61206990 & 61207024 & AAACTTGCTT & TCACTTTACTCTGT & GGACTTGCCC & 14 & [26] \\ \hline DOCK9 & 13 & 98270727 & 98270761 & GGGCAAGTCC & ACAGTGCAAAGTAA & AAGCAAGTTT & 14 & [25] \\ \hline GRIN2A & 16 & 9796860 & 9796894 & AAACTTGCTT & TGACTTTACTCCAT & GGACTTGCCC & 14 & [25] \\ \hline ACCN1 & 17 & 28722009 & 28722043 & AGGCAAGTCC & GCAGTGCAAAGCGA & AAGCAAGTTT & 14 & [25] \\ \hline \end{tabular} \end{table}
PMC2719629_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Species} & \textbf{Sequences} & \textbf{KOG Classifications} \\ \hline Daphnia pulex & 30940 & 15806 \\ \hline Ostreococcus tauri & 7725 & 4733 \\ \hline Trichoderma virens & 11643 & 6879 \\ \hline Xenopus tropicalis & 27916 & 27617 \\ \hline \end{tabular} \end{table}
PMC2719630_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Species} & \textbf{Predictions} & \textbf{OrthoSelect} & \textbf{Best-hit strategy} \\ \hline Daphnia pulex & 12696 & 98\% & 86\% \\ \hline Ostreococcus tauri & 4742 & 91\% & 76\% \\ \hline Trichoderma virens & 5886 & 99\% & 87\% \\ \hline Xenopus tropicalis & 18556 & 84\% & 69\% \\ \hline \end{tabular} \end{table}
PMC2719630_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Value} & \textbf{OrthoSelect} \\ \hline Specificity & 98\% \\ \hline Cases where \textbf{OrthoSelect} found better sequences & 63\% \\ \hline Number of additional sequences found & 270 \\ \hline Number of additional sequences found (good) & 268 \\ \hline Number of additional sequences found (bad) & 2 \\ \hline Number of sequences missed & 197 \\ \hline Ratio of additional/missed sequences & +4\% \\ \hline \end{tabular} \end{table}
PMC2719630_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Test Set} & \textbf{Precision} & \textbf{Recall} & \textbf{F-score} \\ \hline Documents & 61.8\% & 79.1\% & 69.5\% \\ \hline Sentences & 80.1\% & 30.3\% & 44.0\% \\ \hline Annotations & 97.3\% & 65.7\% & 78.8\% \\ \hline \end{tabular} \end{table}
PMC2719631_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Reason(s) for search failure} & \textbf{Percentage of total sentences (n = 78)} \\ \hline Non-standard protein nomenclature (NSN) & 39.7\% (n = 31) \\ \hline Missing category term(s) (MT) & 3.8\% (n = 3) \\ \hline Information spread over multiple sentences (IMS) & 11.5\% (n = 9) \\ \hline Information expressed with <3 categories (IFC) & 6.4\% (n = 5) \\ \hline NSN + MT & 7.7\% (n = 6) \\ \hline NSN + IMS & 3.8\% (n = 3) \\ \hline NSN + IFC & 3.8\% (n = 3) \\ \hline MT + IMS & 10.3\% (n = 8) \\ \hline MT + IFC & 1.3\% (n = 1) \\ \hline NSN + MT + IMS & 6.4\% (n = 5) \\ \hline Technical issues & 5.1\% (n = 4) \\ \hline \end{tabular} \end{table}
PMC2719631_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Reason for search failure} & \textbf{Percentage of total sentences (n = 29)} \\ \hline Run-on sentence or table contents & 44.8\% (n = 13) \\ \hline Inappropriate category term & 17.2\% (n = 5) \\ \hline Linguistic ambiguity & 37.9\% (n = 11) \\ \hline \end{tabular} \end{table}
PMC2719631_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{Patient #} & \textbf{Sex} & \textbf{Age (yrs)} & \textbf{Tumor Location and Grade} & \textbf{History of ETOH or Smoking} & \textbf{Pathological Subtypes} \\ \hline \multicolumn{2}{c|}{Normal Tissues} \\ \hline A9 & F & 32 & tonsillectomy & No & Follicular hyperplasia \\ \hline B9 & F & 30 & tonsillectomy & ETOH/Smoking & Follicular hyperplasia \\ \hline C9 & M & 40 & tonsillectomy & No & Follicular hyperplasia \\ \hline Tumors \\ \hline A1 & / & / & Base of tongue Grade 3 & / & Primary SCCA \\ \hline A6 & / & / & Base of tongue Grade 3 & / & Primary SCCA \\ \hline E1 & F & 68 & Base of tongue Grade 4 & ETOH/Smoking & Recurrent SCCA \\ \hline I1 & M & 38 & Base of tongue & ETOH/Smoking & Primary SCCA \\ \hline F1 & F & 65 & Larynx, Grade 2 & ETOH/Smoking & Primary SCCA \\ \hline C1 & M & 53 & Larynx, Grade 3 & ETOH/Smoking & Primary SCCA \\ \hline D1 & F & 40 & Larynx, Grade 3 & No & Metastatic, unknown primary \\ \hline A3 & / & / & Lymph node-neck & / & Primary SCCA \\ \hline A5 & / & / & Lymph node-neck & / & Primary SCCA \\ \hline H1 & F & 44 & Lymph node-neck, Grade 3 & No & Primary SCCA \\ \hline B1 & M & 72 & Tonsil, Grade 3 & No ETOH, Smoking & Primary SCCA \\ \hline B2 & M & 60 & Tonsil & ETOH/Smoking & Primary SCCA \\ \hline B5 & M & 62 & Tonsil & ETOH/Smoking & Primary SCCA \\ \hline B4 & M & 53 & Buccal mucosa & ETOH, Minimal Smoking & Recurrent SCCA \\ \hline G1 & M & 72 & Buccal mucosa & Minimal ETOH/Smoking & Primary SCCA \\ \hline A2 & M & 60 & Supraglottic & / & Primary SCCA \\ \hline B3 & F & 72 & Supraglottic Grade 4 & ETOH/Smoking & Recurrent SCCA \\ \hline \end{tabular} \end{table}
PMC2719634_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Instrument} & \textbf{Author} & \textbf{Reason for exclusion} \\ \hline Assisted Living Facilities Medication Assessment & Meade 2001 [21] & • No psychometric evaluation \\ \hline Dexterity Test & Begley 1997 [22] & • Insufficient detail* • No psychometric evaluation • Assessment of physical ability only \\ \hline Everyday Cognitive Battery & Allaire 1999 [23] & • Multi-domain tool† • Insufficient detail* • Assessment of cognitive ability only \\ \hline Everyday Problems Test & Willis 1996 [24] & • Multi-domain tool† • Insufficient detail* • Assessment of cognitive ability only \\ \hline Functional Limitations Assessment & Hurd 1986 [25] & • No psychometric evaluation \\ \hline Medication Management Test & Corrigan 1994 [26] & • Insufficient detail* \\ \hline Medication Regimen Adherence Capacity Test & Fitten 1995 [27] & • Psychometric evaluation of only part of the test \\ \hline Observed Tasks of Daily Living (OTDL) & Diehl 1995 [28] & • Multi-domain tool† \\ \hline Occupational Therapy Assessment Scale (OTAS) & Fairbrother 1997 [29] & • Multi-domain tool† • Insufficient detail* \\ \hline Occupational Therapy Assessment of Performance and Support (OTAPS) & Nadler 1993 [30] & • Multi-domain tool† • Insufficient detail* \\ \hline Reading/Comprehension and Task Performance Tool & Bailey 1995 [31] & • Insufficient detail* \\ \hline Regimen Comprehension Scale & Yamada 2001 [32] & • Assessment of cognitive ability only • Insufficient detail* \\ \hline Structured Assessment of Independent Living Skills (SAILS) & Mahurin 1991 [33] & • Multi-domain tool† \\ \hline Self-Administration of Medication tool & Manias 2006 [34] & • No standardised structured observation of task performance \\ \hline Self-Medication Risk Assessment \textbf{Instrument} & Fuller 2005 [35] & • No standardised structured observation of task performance \\ \hline Structured Home Interview & Sedgeworth 1990 [36] & • Insufficient detail* \\ \hline Timed Activities of Daily Living (TIADL) & Owsley 2002 [37] & • Multi-domain tool† • Assessment of cognitive ability only \\ \hline Virtual Reality Apartment Medication Management Assessment & Kurtz 2007 [38] & • Assessment of cognitive ability only \\ \hline \end{tabular} \end{table}
PMC2719637_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|} \hline \textbf{Experiment} & \textbf{Cd2+ (mmol/L)} & \textbf{Ca2+ (mmol/L)} & \textbf{NaHCO3 (mmol/L)} & \textbf{pH} & \textbf{SIot} & \textbf{SIcal} & \textbf{SImaxa} & \textbf{XCdb} \\ \hline Cd.1 & 0.1 & - & 0.1 & 8.4 & 3.17 & - & - & - \\ \hline Cd.2 & 0.1 & - & 0.1 & 8.5 & 3.35 & - & - & - \\ \hline Cd.3 & 0.1 & - & 0.1 & 7.96 & 2.34 & - & - & - \\ \hline Cd.4 & 0.1 & - & 0.1 & 8.1 & 2.6 & - & - & - \\ \hline Cd.5 & 0.1 & - & 0.1 & 8.23 & 2.81 & - & - & - \\ \hline Cd.6 & 0.1 & - & 0.1 & 8.2 & 2.75 & - & - & - \\ \hline Cd.7 & 0.1 & - & 0.1 & 8.22 & 2.83 & - & - & - \\ \hline Cd.8 & 0.1 & - & 0.1 & 8.28 & 2.91 & - & - & - \\ \hline Cd.9 & 0.1 & - & 0.1 & 8.24 & 2.83 & - & - & - \\ \hline Cd.10 & 0.1 & - & 0.1 & 8.27 & 2.89 & - & - & - \\ \hline Cd.11 & 0.1 & - & 0.1 & 8.08 & 2.56 & - & - & - \\ \hline Cd.12 & 0.1 & - & 0.1 & 8.2 & 2.75 & - & - & - \\ \hline Cd.13 & 0.001 & 0.34 & 0.9 & 8.75 & 1.54 & 1.63 & 1.89 & 0.92 \\ \hline Cd.14 & 0.001 & 0.34 & 0.9 & 8.51 & 1.29 & 0.25 & 1.32 & 0.92 \\ \hline Cd.15 & 0.001 & 0.34 & 0.9 & 9 & 2.12 & 1.1 & 2.16 & 0.91 \\ \hline Cd.16 & 0.001 & 0.34 & 0.9 & 8.54 & 1.36 & 0.31 & 1.4 & 0.92 \\ \hline \end{tabular} \end{table}
PMC2719640_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \h\textbf{line} \textbf{line} & \textbf{Location} & \textbf{2c-value} & \textbf{ploidy} \\ \h\textbf{line} Bd21-3 & Iraq & 0.76 & diploid \\ \h\textbf{line} population samples & Adiyaman & 0.69* & diploid \\ \h\textbf{line} Adi-5 & Adiyaman & 0.71 & diploid \\ \h\textbf{line} Adi-P1 & Adiyaman & 1.41 & poly\textbf{ploidy} \\ \h\textbf{line} population samples & Balli & 1.32* & poly\textbf{ploidy} \\ \h\textbf{line} population samples & Bismil & 0.7* & diploid \\ \h\textbf{line} population samples & Gaziantep & 0.69* & diploid \\ \h\textbf{line} population samples & Iskenderun & 1.31* & poly\textbf{ploidy} \\ \h\textbf{line} population samples & Kahta & 0.7* & diploid \\ \h\textbf{line} Kah-2 & Kahta & 0.72 & diploid \\ \h\textbf{line} population samples & Kozluk & 0.68* & diploid \\ \h\textbf{line} population samples & Tekirdag & 0.7* & diploid \\ \h\textbf{line} \end{tabular} \end{table}
PMC2719641_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \multicolumn{3}{c|}{\textbf{Microarray data of 6 genes}} \\ \hline \textbf{Gene} & \textbf{Transcript ID} & \textbf{The ratio of wrky2 mutants vs WT} \\ \hline ABI5 & At2G36270 & 2.30 \\ \hline ABI3 & At3G24650 & 6.06 \\ \hline Em1 & At3G51810 & 4.29 \\ \hline Em6 & At2G40170 & 5.28 \\ \hline MYB33 & At5G06100 & 1.15 \\ \hline MYB101 & At2G32460 & 0.62 \\ \hline \end{tabular} \end{table}
PMC2719644_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \multicolumn{3}{c|}{\textbf{Quantitative RT-PCR primers}} \\ \hline \textbf{Gene} & \multicolumn{2}{c|}{\textbf{Primer sequences (5'->3')}} \\ \hline \textbf{ABI5} & \textbf{Primer forward} & \textbf{AGATGACACTTGAGGATTTCTTGGT} \\ \hline AT2G36270 & Primer reverse & TGGTTCGGGTTTGGATTAGG \\ \hline ABI3 & \textbf{Primer forward} & CTGATTCTTGAATGGGTC \\ \hline AT3G24650 & Primer reverse & TTGTTATTAGGGTTAGGGT \\ \hline Em1 & \textbf{Primer forward} & CGGAGGAAGAAGGGATTGAGA \\ \hline AT3G51810 & Primer reverse & TGCCAAACACGGAACCTACA \\ \hline Em6 & \textbf{Primer forward} & GCAAAGAAGGGCGAGACC \\ \hline AT2G40170 & Primer reverse & TCCTCCTCAGCGTGTTCC \\ \hline WRKY2 & \textbf{Primer forward} & TTTCTTTGGGTTACGATG \\ \hline AT5G56270 & Primer reverse & CACAACAACTCTTGGCTC \\ \hline ACT2 & \textbf{Primer forward} & TGTGCCAATCTACGAGGGTTT \\ \hline AT3G18780 & Primer reverse & TTTCCCGCTCTGCTGTTGT \\ \hline \end{tabular} \end{table}
PMC2719644_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline \textbf{Stimulation} & \textbf{\textbf{Right}} & \textbf{\textbf{Right}} & \textbf{\textbf{Left}} & \textbf{\textbf{Left}} \\ \hline Hemisphere & \textbf{\textbf{Right}} & \textbf{\textbf{Left}} & \textbf{\textbf{Right}} & \textbf{\textbf{Right}} \\ \hline Talairach Coordinate & 62.37, -10.43, 24.47 & -57.42, -14.91, 32.07 & 63.36, -9.55, 22.59 & -54.45, -10.43, 43.82 \\ \hline Brodmann Area & 3 & 3 & 3 & 3 \\ \hline \end{tabular} \end{table}
PMC2719647_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline & \textbf{X loc} & \textbf{Y loc} & \textbf{Z loc} & \textbf{X orient} & \textbf{Y orient} & \textbf{Z orient} \\ \hline LH tangential & -0.53 & 0.08 & 0.11 & 0.1 & 0.3 & 0.9 \\ \hline LH radial & -0.53 & 0.08 & 0.11 & 0.5 & -0.8 & -0.5 \\ \hline RH tangential & 0.53 & 0.08 & 0.11 & 0.0 & 0.2 & 1.0 \\ \hline RH radial & 0.53 & 0.08 & 0.11 & -0.1 & -1.0 & -0.3 \\ \hline Residual & -0.07 & -0.40 & -0.01 & 0.0 & -0.5 & -0.9 \\ \hline \end{tabular} \end{table}
PMC2719648_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & \textbf{HC} & \textbf{SZ} & \textbf{Statistic} & \textbf{p} \\ \hline Age (years) & 44.4 +/- 6.8 & 39.8 +/- 10.5 & t[32] = 1.47 & 0.151 \\ \hline Parental socio-economic status (ref. 24) & 3.1 +/- 1.3 & 3.2 +/- 0.9 & t[28] = -0.316 & 0.754 \\ \hline Handedness & 0.78 +/- 0.16 & 0.77 +/- 0.25 & t[32] = 0.172 & 0.864 \\ \hline Age of onset (years) & & 26.1 +/- 8.0 \\ \hline Positive sym\textbf{p}tom total (SAPS) & & 9.0 +/- 4.2 \\ \hline Negative sym\textbf{p}tom total (SANS) & & 13.9 +/- 4.9 \\ \hline Medication dosage (chlor\textbf{p}romazine equivalents) & & 450 +/- 306 range 83–1200 \\ \hline \end{tabular} \end{table}
PMC2719648_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline & \multicolumn{7}{c|}{\textbf{DISTRIBUTION OF SPOLIGOTYPES PER DISTRICT}} \\ \hline \textbf{Isolate} & \multirow{3}{*}{\textbf{Spoligotype SB Number*}} & \multirow{3}{*}{\textbf{L S K}} & \multirow{3}{*}{\textbf{M Z K}} & \multirow{3}{*}{\textbf{C H M}} & \multirow{3}{*}{\textbf{M B W}} & \multirow{3}{*}{\textbf{M Z E}} & \multirow{3}{*}{\textbf{N M A}} & \textbf{Total} & \textbf{Frequency} \\ \hline & \textbf{No.} & \textbf{(\%)} \\ \hline \\ \hline C9 & SB1767 & & & & & 1 & & 1 & 3.2 \\ \hline C19 & SB0162 & & & & & & 1 & 1 & 3.2 \\ \hline C21 & SB1763 & & & & 1 & & & 1 & 3.2 \\ \hline C26 & SB1764 & & & & & & 1 & 1 & 3.2 \\ \hline C14 & SB1572 & 1 & & & & & & 1 & 3.2 \\ \hline C42 & SB1765 & & & & & & 1 & 1 & 3.2 \\ \hline C16 & SB1536 & & & & & & 1 & 1 & 3.2 \\ \hline C4, C13, C15 & SB0871 & & & 1 & 1 & & 1 & 3 & 9.7 \\ \hline C41 & SB1766 & & & & & & 1 & 1 & 3.2 \\ \hline C2, C3, C5, \\ \hline C6, C8, C17, \\ \hline C18, C22, \\ \hline C24, C25, \\ \hline C27, C28, & SB0120 & 5 & 2 & & 3 & 4 & 6 & 20 & 64.5 \\ \hline C29, C31, \\ \hline C38, C39, \\ \hline C40, C44, \\ \hline C45, C46 \\ \hline \textbf{Total} number & & 6 & 2 & 1 & 5 & 5 & 12 & 31 \\ \hline \end{tabular} \end{table}
PMC2719650_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Spoligotype1} & \textbf{Shared type2} & \textbf{Geographical distribution} \\ \hline Sp1 & SB0120 & France, Belgium, Brazil, South Africa, Sri Lanka, Iran, The Netherlands, Spain, China, Japan, Portugal, Russia, Denmark, Zambia \\ \hline Sp2 & SB0871 & France \\ \hline Sp3 & SB1763* & Zambia \\ \hline Sp4 & SB1764* & Zambia \\ \hline Sp5 & SB1572 & Italy \\ \hline Sp6 & SB1765* & Zambia \\ \hline Sp7 & SB1536 & Italy \\ \hline Sp8 & SB1766* & Zambia \\ \hline Sp9 & SB1767* & Zambia \\ \hline Sp10 & SB0162 & Belgium \\ \hline \end{tabular} \end{table}
PMC2719650_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Discourse} & \textbf{Databases} & \textbf{Keywords} & \textbf{Articles (n)} \\ \hline Print media & Lexis-Nexis Academic Factiva & "Ritalin" "methylphenidate" "smart drugs" "Ritalin & study aid" "cognitive enhancement" "neuroethics" "stimulant abuse" "non-medical use" "illicit use" & 20*† \\ \hline Bioethics literature & PubMed (bioethics limit) Expanded Academic & & 14 \\ \hline Public health literature & PubMed Expanded Academic & & 7 \\ \hline \end{tabular} \end{table}
PMC2719652_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Lay designation} & \textbf{Occurrences} \\ \hline "study aid" [37] & 9 \\ \hline "brain steroid" [18] & 4 \\ \hline "smart drug(s)" [21] & 4 \\ \hline "vitamin R" [37] & 4 \\ \hline "poor man's cocaine" [33] & 3 \\ \hline "study tool(s)" [18] & 2 \\ \hline "wonder drug" [38] & 2 \\ \hline "new chemical aid" [18] & 1 \\ \hline "smart pill(s)" [35] & 1 \\ \hline "cramming drug" [34] & 1 \\ \hline "academic steroids" [37] & 1 \\ \hline "steroids of academia" [20] & 1 \\ \hline "legal speed" [36] & 1 \\ \hline "kiddie speed" [19] & 1 \\ \hline \end{tabular} \end{table}
PMC2719652_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \multicolumn{2}{c|}{\textbf{Print media}} \\ \hline \textbf{Portrayal} & \textbf{“Lifestyle choice”: “better living through chemistry” [39]; “short cut in learning”; “new kind of drug abuse” [18].} \\ \hline Examples of headlines & "Students taking danger drug to help with exams"; " 'Smart pills' are on the rise. But is taking them wise?"; "New campus high: Illicit prescription drugs". \\ \hline Reported risks* & Physiological addiction (8); palpitations (7); psychological addiction (6); heart attack (5); unspecified cardiac risks (4); loss of appetite (4); hallucinations (4); stroke (2); tremors (2); increase in blood pressure (2); weight loss (2); vomiting (2); dizziness (2); seizures (2); withdrawal symptoms (2); require increasing amounts of drug (1); cardiac arrhythmia (1); overdose (1); changes in brain cell chemistry (1); fatigue (1); death (1); dry mouth (1). \\ \hline Reported benefits† & Boost concentration (8); increase focus (7); increase energy (3); increase alertness (1); reduce appetite (1); eliminate jitters (1); filter out distractions (1); increase motivation (1); accumulate more information in less time (1); increase confidence (1); increase organization (1); increase retention of information (1); think more rationally (1); general feeling of well-being (1); make you feel smarter (1); make mundane tasks seem fun (1); enhance studying (1); do work faster (1); maintain high performance level (1); boost brain activity (1). \\ \hline & Bioethics \\ \hline \textbf{Portrayal} & "Cognitive enhancement": " 'neuroenhancement' (...) This term includes the use of drugs and other interventions to modify brain processes with the aim of enhancing memory, mood and attention in people who are not impaired by illness or disorder"[40]. \\ \hline Examples of headlines & "Neurocognitive enhancement: what can we do and what should we do?" and "Cosmetic neurology: The controversy over enhancing movement, mentation, and mood". \\ \hline Reported risks* & Addiction (3); toxicity (1). \\ \hline Reported benefits† & Improve attention (4); improve memory (4); improve performance (2); increase focus (1); improve concentration (1); improve planning (1); think faster (1); stabilize mood (1); promote creativity (1). \\ \hline & Public health \\ \hline \textbf{Portrayal} & "Abuse", "misuse", "illicit drug use": "Ritalin (Novartis Pharmaceuticals Corp., East Hanover, NJ) has received the most attention in medical literature, little information is available regarding which specific stimulants are used illicitly by college students" [41]. \\ \hline Examples of headlines & "Student perceptions of methylphenidate abuse at a public liberal arts college" and "Stimulant medication use, misuse, and abuse in an undergraduate and graduate student sample". \\ \hline Reported risks* & Addiction (2); cardiovascular implications (1); withdrawal symptoms (1); increase in blood pressure (1); headache (1); overdose (1); blocking veins if injected/snorted (1); panic episodes (1); aggressive behavior (1); suicidal or homicidal tendencies (1). \\ \hline Reported benefits† & Decreases fatigue (2); increases energy (1); increases dopaminergic activity (1); maintain high performance level (1); increase alertness (1). \\ \hline \end{tabular} \end{table}
PMC2719652_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline \textbf{Ethical, legal and social issues} & \multicolumn{4}{c|}{\textbf{Affirmation}} & \multicolumn{4}{c|}{\textbf{Negation}} & \textbf{\textbf{\textbf{Total}} Frequency} \\ \hline & \textbf{\textbf{PM}} & \textbf{\textbf{B}} & \textbf{\textbf{PH}} & \textbf{\textbf{Total}} & \textbf{\textbf{PM}} & \textbf{\textbf{B}} & \textbf{\textbf{PH}} & \textbf{\textbf{Total}} \\ \hline Social integration and acceptability & 11 & 13 & - & 24 & 5 & - & - & 5 & 29 \\ \hline Social meaning & 11 & 9 & 5 & 25 & 1 & 2 & - & 3 & 28 \\ \hline Unsafe & 2 & 11 & 2 & 15 & 3 & 2 & 2 & 7 & 22 \\ \hline Abuse & 11 & 1 & 5 & 17 & 1 & 1 & 1 & 3 & 20 \\ \hline Cheating & 5 & 8 & - & 13 & 3 & 3 & - & 6 & 19 \\ \hline Inauthenticity, identity and personhood & 1 & 12 & - & 13 & - & 5 & - & 5 & 18 \\ \hline Injustice and inequalities & - & 10 & - & 10 & - & 6 & - & 6 & 16 \\ \hline Overprescription & 9 & 2 & 4 & 15 & 1 & - & - & 1 & 16 \\ \hline Lack of autonomy, individual choice and informed consent & - & 10 & - & 10 & - & 5 & - & 5 & 15 \\ \hline Illegality & 8 & 2 & - & 10 & 3 & 1 & - & 4 & 14 \\ \hline Commercialization & 1 & 7 & - & 8 & - & 1 & - & 1 & 9 \\ \hline Inefficacy & 2 & 4 & 1 & 7 & - & - & - & - & 7 \\ \hline \end{tabular} \end{table}
PMC2719652_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \multicolumn{3}{c|}{\textbf{A. Proposed recommendations to prevent non-medical use of MPH}} \\ \hline \textbf{Print media} & \textbf{Bioethics} & \textbf{Public health} \\ \hline Diagnosing ADHD more carefully [37,38,50] Supervising of students with stimulant prescriptions [33,47] Teaching students effective study skills and stress management [17,37] Informing students and staff of the dangers of abusing prescription drugs [18,33,34,37] & Criminalizing non-approved uses of medications [3,48] Prohibiting prescription of drugs for lifestyle purposes by doctors [48] Obliging manufacturers to declare safety data for unapproved uses to the FDA [48] Subsidizing cognition enhancing drugs to allow equal access [40,48] Establishing a "ceiling" as the maximum cognitive enhancement permissible [48,53] & Ensuring prescription compliance and responsible prescription practices [49,52] Prescribing preparations that are less easily abused [41,51] Identifying persons who are liable to abuse medication [49] Educating healthcare providers dealing with university populations as to the abuse potential of stimulants [51,52] \\ \hline \multicolumn{2}{c|}{B. Identified} & MPH \\ \hline \textbf{Print media} & \textbf{Bioethics} & \textbf{Public health} \\ \hline Logistical problems of enforcing a ban [37,38,54] Perceived safety of MPH makes convincing students about its dangers more difficult [35,37] Abundance of MPH in healthcare system [50] Misuse of MPH bypasses traditional sources of information on indications and risks when taking a prescription medication [37] & Difficult to propose a ban on cognitive enhancers because of their routine use in treatment [40,48,53] Ban is liable to encourage a black market and be just as coercive as social pressure [40,48,53] FDA has little experience in assessing social cost/benefit of a drug and thus is unfit to take charge of such regulation [53] & None identified \\ \hline \end{tabular} \end{table}
PMC2719652_table_4
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & \multicolumn{2}{c|}{\textbf{CASES}} & \multicolumn{2}{c|}{\textbf{CONTROLS}} \\ \hline & \textbf{\textbf{Median}} & \textbf{\textbf{IQR}} & \textbf{\textbf{Median}} & \textbf{\textbf{IQR}} \\ \hline P. falciparum \\ \hline <1 & 9,480 & [640, 39,800] & 3000 & [740, 14,800] \\ \hline 1 & 19,880 & [4,640, >40,000] & 1,200 & [160, 5,360] \\ \hline 2–3 & 21,100 & [5,600, >40,000] & 1,600 & [320, 6,550] \\ \hline 4–6 & 17,220 & [3,520, >40,000] & 680 & [200, 2,560] \\ \hline 7–9 & 14,840 & [2,440, >40,000] & 480 & [160, 1,680] \\ \hline 10–19 & 9,080 & [1,100, 31,460] & 240 & [80, 720] \\ \hline 20+ & 1,600 & [320, 9,610] & 160 & [80, 440] \\ \hline P. vivax \\ \hline <1 & 4,480 & [240, 15,260] & 120 & [70, 1,520] \\ \hline 1 & 5,540 & [1,360, 12,870] & 480 & [130, 2,960] \\ \hline 2–3 & 4,500 & [920, 12,820] & 440 & [120, 1,600] \\ \hline 4–6 & 2,440 & [320, 9,120] & 200 & [120, 640] \\ \hline 7–9 & 1,280 & [200, 7,480] & 160 & [80, 280] \\ \hline 10–19 & 300 & [80, 3,380] & 80 & [40, 200] \\ \hline 20+ & 120 & [80, 280] & 80 & [40, 160] \\ \hline P. malariae \\ \hline <1 & 220 & [90, 350] & 80 & [40, 740] \\ \hline 1 & 420 & [120, 1,910] & 200 & [40, 360] \\ \hline 2–3 & 1380 & [210, 3,360] & 320 & [120, 800] \\ \hline 4–6 & 1160 & [450, 3,240] & 320 & [120, 680] \\ \hline 7–9 & 960 & [280, 2,400] & 160 & [80, 360] \\ \hline 10–19 & 440 & [120, 1760] & 120 & [60, 200] \\ \hline 20+ & 120 & [80, 480] & 80 & [40, 160] \\ \hline \end{tabular} \end{table}
PMC2719654_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & \multicolumn{2}{c|}{\textbf{β0,, Intercept [95\% CI]}} & \multicolumn{2}{c|}{\textbf{β1, Slope, [95\% CI]}} \\ \hline \textbf{P. falciparum (excluding < 1 year old)} & \textbf{-4.29} & \textbf{[-4.62, -3.97]} & \textbf{1.33} & \textbf{[1.24, 1.42]} \\ \hline P. falciparum (all) & -5.03 & [-5.62, -4.43] & 1.40 & [1.23, 1.57] \\ \hline P. vivax & -5.51 & [-6.07, -4.95] & 1.57 & [1.40, 1.73] \\ \hline P. malariae & -5.75 & [-6.75, -4.75] & 1.56 & [1.26, 1.87] \\ \hline \end{tabular} \end{table}
PMC2719654_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline & \multicolumn{5}{c|}{\textbf{Private health insurance}} \\ \hline \textbf{Lifestyle factors} & \textbf{N} & \textbf{\% column} & \textbf{\% PHI} & \textbf{RR crude*} & \textbf{RR adjusted+} \\ \hline BMI categories‡ \\ \hline Underweight & 3,903 & 4.0 & 61.1 & 0.91 (0.89, 0.94) & 0.97 (0.95, 0.99) \\ \hline Healthy weight§ & 31,256 & 31.9 & 67.0 & 1 & 1 \\ \hline Overweight & 36,027 & 36.8 & 67.4 & 1.01 (1.00, 1.02) & 1.02 (1.01, 1.03) \\ \hline Obese & 19,619 & 20.1 & 61.0 & 0.91 (0.90, 0.92) & 0.97 (0.96, 0.99) \\ \hline Smoking status \\ \hline \textbf{N}ever§ & 55,522 & 56.7 & 69.7 & 1 & 1 \\ \hline Past & 34,989 & 35.8 & 62.8 & 0.90 (0.89, 0.91) & 0.94 (0.93, 0.94) \\ \hline Current & 7,319 & 7.5 & 41.4 & 0.59 (0.58, 0.61) & 0.71 (0.70, 0.73) \\ \hline Alcohol consumption (drinks/week) \\ \hline Zero§ & 31,098 & 31.8 & 55.4 & 1 & 1 \\ \hline 1 to 6 & 28,339 & 29.0 & 70.2 & 1.27 (1.25, 1.28) & 1.11 (1.10, 1.12) \\ \hline 7 to 13 & 17,992 & 18.4 & 72.7 & 1.31 (1.29, 1.33) & 1.12 (1.10, 1.13) \\ \hline 14 to 20 & 10,732 & 11.0 & 72.5 & 1.31 (1.29, 1.33) & 1.11 (1.10, 1.13) \\ \hline 21 and over & 7,642 & 7.8 & 63.0 & 1.14 (1.12, 1.16) & 1.03 (1.01, 1.05) \\ \hline Physical activity (sessions/week) \\ \hline Zero§ & 4,047 & 4.1 & 52.7 & 1 & 1 \\ \hline 1 to 6 & 24,557 & 25.1 & 65.0 & 1.23 (1.20, 1.27) & 1.09 (1.06, 1.12) \\ \hline 7 to 10 & 24,526 & 25.1 & 65.8 & 1.25 (1.21, 1.29) & 1.08 (1.05, 1.11) \\ \hline 11 to 15 & 20,030 & 20.5 & 68.0 & 1.29 (1.25, 1.33) & 1.10 (1.07, 1.13) \\ \hline 16 and over & 22,810 & 23.3 & 65.8 & 1.25 (1.21, 1.29) & 1.07 (1.04, 1.10) \\ \hline Vegetable intake (serves/day) \\ \hline Zero§ & 1,994 & 2.0 & 47.8 & 1 & 1 \\ \hline >0 to 1 & 9,576 & 9.8 & 58.4 & 1.22 (1.16, 1.28) & 1.08 (1.04, 1.13) \\ \hline 2 to 3 & 40,085 & 41.0 & 66.2 & 1.38 (1.32, 1.45) & 1.14 (1.10, 1.19) \\ \hline 4 to 5 & 24,065 & 24.6 & 68.5 & 1.43 (1.37, 1.50) & 1.17 (1.12, 1.22) \\ \hline 6 and over & 20,035 & 20.5 & 65.0 & 1.36 (1.30, 1.42) & 1.17 (1.12, 1.22) \\ \hline Fruit intake (serves/day) \\ \hline Zero§ & 6,225 & 6.4 & 50.7 & 1 & 1 \\ \hline >0 to 1 & 19,018 & 19.4 & 62.5 & 1.23 (1.20, 1.26) & 1.12 (1.09, 1.15) \\ \hline 2 to 3 & 53,961 & 55.2 & 67.4 & 1.33 (1.30, 1.36) & 1.17 (1.15, 1.20) \\ \hline 4 and over & 16,362 & 16.7 & 67.7 & 1.34 (1.30, 1.37) & 1.19 (1.16, 1.22) \\ \hline \end{tabular} \end{table}
PMC2719656_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & \multicolumn{2}{c|}{\textbf{Fearful-deviant}} & \multicolumn{2}{c|}{\textbf{Happy-deviant}} \\ \hline & \textbf{\textbf{Latency range}} & \textbf{\textbf{t- and p-values}} & \textbf{\textbf{Latency range}} & \textbf{\textbf{t- and p-values}} \\ \hline \multirow{6}{*}{Fz} & 109 – 127 & t = 2.2 – 3.5 & 123 – 172 & t = 2.2 – 3.5 \\ \hline & p = .005 – .049 & & p = .005 – .047 \\ \hline 137 – 162 & t = 2.2 – 3.2 \\ \hline & p = .009 – .048 \\ \hline & & 260 – 282 & t = 2.2 – 3.3 \\ \hline & & & p = .007 – .047 \\ \hline \multirow{2}{*}{Cz} & 112 – 156 & t = 2.2 – 3.6 & 124 – 168 & t = 2.2 – 3.9 \\ \hline & p = .005 – .047 & & p = .002 – .047 \\ \hline Pz & No differences & & 281 – 300 & t = 2.2 – 3.9 p = .002 – .048 \\ \hline \multirow{6}{*}{Oz} & 164 – 183 & t = 2.3 – 2.6 & 142–153 & t = 2.2 – 2.9 \\ \hline & p = .023 – .045 & & p = .014 – .049 \\ \hline 296 – 330 & t = 2.6 – 5.5 & 280 – 302 & t = 2.2 – 3.8 \\ \hline & p = .0001 – .046 & & p = .003 – .047 \\ \hline & & 319 – 341 & t = 2.4 – 3.4 \\ \hline & & & p = .006 – .038 \\ \hline \multirow{6}{*}{O1} & & & 140 – 154 & t = 2.2 – 3.3 \\ \hline & & & p = .007 – .049 \\ \hline 174 – 185 & t = 2.6 – 3.2 \\ \hline & p = .008 – .039 \\ \hline 300 – 323 & t = 2.3 – 5.2 & 319 – 341 & t = 2.3 – 3.6 \\ \hline & p = .0001 – .042 & & p = .004 – .040 \\ \hline \multirow{10}{*}{O2} & & & 142 – 151 & t = 2.3 – 2.7 \\ \hline & & & p = .019 – .046 \\ \hline 164 – 185 & t = 2.2 – 4.44 \\ \hline & p = .001 – .048 \\ \hline & & 202 – 218 & t = 2.2 – 2.5 \\ \hline & & & p = .032 – .047 \\ \hline & & 253 – 305 & t = 2.3 – 5.6 \\ \hline & & & p = .0001 – .045 \\ \hline 281 – 331 & t = 2.3 – 4.5 & 318 – 340 & t = 2.4 – 4.6 \\ \hline & p = .001 – .042 & & p = .001 – .038 \\ \hline \end{tabular} \end{table}
PMC2719659_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|l|l|l|l|l|l|l|} \hline & \multicolumn{2}{c|}{\textbf{Global}} & \multicolumn{2}{c|}{\textbf{Europe}} & \multicolumn{2}{c|}{\textbf{Middle East}} & \multicolumn{2}{c|}{\textbf{Africa}} & \multicolumn{2}{c|}{\textbf{Central South Asia}} & \multicolumn{2}{c|}{\textbf{East Asia}} & \multicolumn{2}{c|}{\textbf{Oceania}} & \multicolumn{2}{c|}{\textbf{America}} \\ \hline \textbf{BritAIMs} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{Fst}}}}}}}} & \textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{\textbf{P}}}}}}}} \\ \hline rs7696175 & 0.074 & 0.551 & 0.129 & 0.000 & 0.002 & 0.840 & 0.052 & 0.469 & 0.011 & 0.748 & 0.018 & 0.802 & 0.067 & 0.439 & 0.118 & 0.333 \\ \hline rs1460133 & 0.035 & 0.842 & 0.062 & 0.043 & 0.027 & 0.286 & 0 & 1 & 0.022 & 0.502 & 0.010 & 0.916 & NA & NA & 0.042 & 0.695 \\ \hline rs9378805 & 0.115 & 0.321 & 0.030 & 0.280 & 0.043 & 0.136 & 0.019 & 0.796 & 0.020 & 0.554 & 0.016 & 0.831 & 0.072 & 0.424 & 0.027 & 0.754 \\ \hline rs11790408 & 0.067 & 0.594 & 0.043 & 0.141 & 0.088 & 0.022 & 0.028 & 0.714 & 0.046 & 0.169 & 0.009 & 0.920 & 0.015 & 0.709 & 0.108 & 0.370 \\ \hline rs12295525 & 0.068 & 0.591 & 0.034 & 0.226 & 0.008 & 0.666 & 0.047 & 0.513 & 0.024 & 0.454 & 0.017 & 0.809 & NA & NA & 0.021 & 0.820 \\ \hline rs12797951 & 0.106 & 0.365 & 0 & 1 & 0.105 & 0.015 & 0.037 & 0.611 & 0.053 & 0.116 & 0.061 & 0.136 & NA & NA & 0.175 & 0.167 \\ \hline rs10774241 & 0.103 & 0.383 & 0 & 1 & 0 & 1 & 0.090 & 0.226 & 0.024 & 0.470 & 0.029 & 0.580 & 0.004 & 0.760 & 0.139 & 0.247 \\ \hline rs17449560 & 0.036 & 0.835 & 0.017 & 0.520 & 0.043 & 0.135 & 0.112 & 0.146 & 0.003 & 0.909 & 0.017 & 0.814 & 0.199 & 0.210 & 0.061 & 0.581 \\ \hline rs3760843 & 0.033 & 0.855 & 0.024 & 0.369 & 0 & 1 & 0.073 & 0.320 & 0.014 & 0.665 & 0.021 & 0.747 & 0.144 & 0.295 & 0.139 & 0.247 \\ \hline rs2143877 & 0.078 & 0.529 & 0.046 & 0.117 & 0.011 & 0.585 & 0.053 & 0.460 & 0.004 & 0.892 & 0.015 & 0.857 & 0.005 & 0.754 & 0.038 & 0.714 \\ \hline \end{tabular} \end{table}
PMC2719660_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Continental Group} & \textbf{Median Fst} & \textbf{P value} \\ \hline Europe & 0.0316 & 0.039 \\ \hline Central South Asia & 0.021 & 0.574 \\ \hline Africa & 0.0492 & 0.49 \\ \hline Middle East & 0.01895 & 0.302 \\ \hline East Asia & 0.017 & 0.992 \\ \hline America & 0.08465 & 0.414 \\ \hline Oceania & 0.067 & 0.362 \\ \hline \end{tabular} \end{table}
PMC2719660_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & & \textbf{Neuropilin-2} & & \textbf{p value} \\ \hline Factor & & Negative & Positive \\ \hline \multirow{2}{*}{Age} & < 50 & 35 (54\%) & 30 (46\%) & 0.0911 \\ \hline �51 & 18 (38\%) & 30 (62\%) \\ \hline \multirow{4}{*}{Histology} & Ductal & 47 (45\%) & 57 (55\%) & 0.4328 \\ \hline Lobular & 3 (60\%) & 2 (40\%) \\ \hline Medullary & 1 (100\%) & 0 (0\%) \\ \hline Mucinous & 2 (67\%) & 1 (33\%) \\ \hline \multirow{2}{*}{Tumor size} & pT1 & 19 (53\%) & 17 (47\%) & 0.4240 \\ \hline pT2–4 & 34 (44\%) & 43 (56\%) \\ \hline \multirow{2}{*}{Lymph node metastasis} & Negative & 31 (57\%) & 23 (43\%) & 0.0389 \\ \hline Positive & 22 (37\%) & 37 (63\%) \\ \hline \multirow{2}{*}{Estrogen receptor} & Negative & 22 (49\%) & 23 (51\%) & 0.8476 \\ \hline Positive & 31 (46\%) & 37 (54\%) \\ \hline \multirow{2}{*}{Progesterone receptor} & Negative & 24 (47\%) & 27 (53\%) & 1.0000 \\ \hline Positive & 29 (47\%) & 33 (53\%) \\ \hline \multirow{2}{*}{Histological grade} & I and II & 34 (51\%) & 33 (49\%) & 0.3440 \\ \hline III & 19 (41\%) & 27 (59\%) \\ \hline \multirow{2}{*}{VEGF-C} & Negative & 17 (85\%) & 3 (15\%) & < 0.001 \\ \hline Positive & 36 (39\%) & 57 (61\%) \\ \hline \multirow{2}{*}{CXCR4 (cytoplasmic)} & Negative & 37 (65\%) & 20 (35\%) & < 0.001 \\ \hline Positive & 16 (29\%) & 40 (71\%) \\ \hline \multirow{2}{*}{CXCR4 (nuclei)} & Negative & 42 (50\%) & 42 (50\%) & 0.2879 \\ \hline Positive & 11 (38\%) & 18 (62\%) \\ \hline \multirow{2}{*}{Distant metastasis} & Negative & 41 (49\%) & 43 (51\%) & 0.5243 \\ \hline Positive & 12 (41\%) & 17 (59\%) \\ \hline \end{tabular} \end{table}
PMC2719661_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Sample} & \textbf{CA125 (unit/ml)} & \textbf{Claudin-4*} \\ \hline N32 & 0 & 1 \\ \hline N2 & 0 & 0 \\ \hline N3 & 41 & 0 \\ \hline N4 & 4 & 0 \\ \hline N5 & 122 & 0 \\ \hline N6 & 44 & 0 \\ \hline N7 & 0 & 0 \\ \hline N8 & 0 & 0 \\ \hline N9 & 0 & 0 \\ \hline N21 & 0 & 0 \\ \hline N22 & 8 & 0 \\ \hline N23 & 0 & 0 \\ \hline N24 & 0 & 0 \\ \hline N25 & 76 & 0 \\ \hline N26 & 27 & 0 \\ \hline N27 & 6 & 0 \\ \hline N28 & 4 & 0 \\ \hline N29 & 0 & 0 \\ \hline N30 & 0 & 0 \\ \hline N31 & 20 & 0 \\ \hline N33 & 1 & 0 \\ \hline N34 & 0 & 0 \\ \hline N35 & 0 & 0 \\ \hline N36 & 47 & 0 \\ \hline N37 & 0 & 0 \\ \hline N38 & 0 & 0 \\ \hline N39 & 0 & 0 \\ \hline N19 & 9 & 0 \\ \hline N15 & 0 & 0 \\ \hline N11 & 0 & 0 \\ \hline N1 & 0 & 0 \\ \hline N10 & 30 & 0 \\ \hline N41 & 0 & 0 \\ \hline N42 & 0 & 0 \\ \hline N43 & 0 & 0 \\ \hline N44 & 22 & 0 \\ \hline N45 & 80 & 0 \\ \hline N46 & 0 & 0 \\ \hline N47 & 16 & 0 \\ \hline N48 & 99 & 0 \\ \hline N49 & 27 & 0 \\ \hline N51 & 0 & 0 \\ \hline N52 & 0 & 0 \\ \hline N53 & 85 & 0 \\ \hline N54 & 0 & 0 \\ \hline N55 & 9 & 0 \\ \hline N56 & 4 & 0 \\ \hline N57 & 0 & 0 \\ \hline N58 & 2 & 0 \\ \hline N59 & 171 & 0 \\ \hline \end{tabular} \end{table}
PMC2719664_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline & \textbf{Cl4 +} & \textbf{Cl4 -} \\ \hline CA125 Positive & 31 & 14 \\ \hline CA125 Negative & 1 & 17 \\ \hline \end{tabular} \end{table}
PMC2719664_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & & \multicolumn{2}{c|}{\textbf{Score of CA 9 expression}} \\ \hline \multicolumn{2}{c|}{\textbf{Patient characteristics (n = 31)}} & \textbf{<80} & \textbf{$\geq$ 80} & \textbf{P value} \\ \hline & & \textbf{(n = 20)} & \textbf{(n = 11)} \\ \hline Age, median (range) & 51.6 (31.8 – 67.8) & 52.6 (33.3 – 66.7) & 50.4 (31.8 – 67.8) & 0.741* \\ \hline Gender \\ \hline Male & 15 & 10 & 5 & 0.809† \\ \hline Female & 16 & 10 & 6 \\ \hline Performance status \\ \hline 0 & 3 & 2 & 1 & 1.000‡ \\ \hline 1 & 25 & 16 & 9 \\ \hline 2 & 3 & 2 & 1 \\ \hline Line of bevacizumab \\ \hline 2nd line & 13 & 9 & 4 & 0.718‡ \\ \hline $\geq$ 3rd line & 18 & 11 & 7 \\ \hline Primary sites \\ \hline Rectum & 12 & 9 & 3 & 0.452‡ \\ \hline Colon & 19 & 11 & 8 \\ \hline Site of distant metastasis \\ \hline Liver & 17 & 10 & 7 & 0.465† \\ \hline Lymph node & 15 & 12 & 3 & 0.081† \\ \hline Lung & 14 & 9 & 5 & 0.981† \\ \hline Omentum & 11 & 9 & 2 & 0.241‡ \\ \hline Bone & 7 & 6 & 1 & 0.372‡ \\ \hline Sum of metastatic sites & 4 & 3 & 1 \\ \hline < 3 & 20 & 13 & 7 & 1.000‡ \\ \hline $\geq$ 3 & 11 & 7 & 4 \\ \hline Combined chemotherapy \\ \hline FOLFOX & 15 & 10 & 5 & 0.439‡ \\ \hline FOLFIRI & 6 & 5 & 1 \\ \hline Fluoropyrimidines alone & 10 & 5 & 5 \\ \hline Treatment responses \\ \hline Complete response & - & - & - \\ \hline Partial response & 6 (19.4\%) & 4 & 2 \\ \hline Stable disease & 13 (41.9\%) & 12 & 1 \\ \hline Disease control rate§ & 19 (61.3\%) & 16 (80.0\%) & 3 (27.3\%) & 0.004‡ \\ \hline Progressive disease & 11 (35.5\%) & 3 & 8 \\ \hline Not evaluable & 1 (3.2\%) & 1 & 0 \\ \hline \end{tabular} \end{table}
PMC2719665_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Genotype} & \textbf{Control (\%) (N = 323)} & \textbf{SPCa (\%) (N = 391)} & \textbf{LPCa (\%) (N = 112)} \\ \hline rs1447295 \\ \hline CC & 218 (67.5) & 217 (55.5) & 71 (63.4) \\ \hline CA & 89 (27.5) & 149 (38.1) & 34 (30.4) \\ \hline AA & 16 (5.0) & 25 (6.4) & 7 (6.2) \\ \hline rs6983267 \\ \hline TT & 147 (45.5) & 151 (38.6) & 48 (42.9) \\ \hline TG & 151 (46.8) & 181 (46.3) & 53 (47.3) \\ \hline GG & 25 (7.7) & 59 (15.1) & 11 (9.8) \\ \hline Allele & Control (\%) (2N = 646) & SPCa (\%) (2N = 782) & LPCa (\%) (2N = 224) \\ \hline rs1447295 \\ \hline C & 525 (81.3) & 583 (74.6) & 176 (78.6) \\ \hline A & 121 (18.7) & 199 (25.4) & 48 (21.4) \\ \hline HWE \\ \hline chi-square & 2.91 & 0.01 & 1.09 \\ \hline p value & 0.09 & 0.93 & 0.30 \\ \hline rs6983267 \\ \hline T & 445 (68.9) & 483 (61.8) & 149 (66.5) \\ \hline G & 201 (31.1) & 299 (38.2) & 75 (33.5) \\ \hline HWE \\ \hline chi-square & 2.65 & 0.16 & 0.44 \\ \hline p value & 0.10 & 0.69 & 0.51 \\ \hline \end{tabular} \end{table}
PMC2719668_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline \multirow{2}{*}{\textbf{Genotype}} & \multirow{2}{*}{\textbf{\textbf{OR*}}} & \multirow{2}{*}{\textbf{Control vs. SPCa 95\% CI}} & \multirow{2}{*}{\textbf{\textbf{p value}}} & \multirow{2}{*}{\textbf{\textbf{OR*}}} & \multirow{2}{*}{\textbf{Control vs. LPCa 95\% CI}} & \multirow{2}{*}{\textbf{\textbf{p value}}} \\ \hline \\ \hline rs1447295 \\ \hline CC & 1.0 & reference & & 1.0 & reference \\ \hline CA & 1.54 & 1.08 – 2.21 & 0.02 & 1.22 & 0.75 – 1.98 & 0.42 \\ \hline AA & 1.29 & 0.62 – 2.73 & 0.50 & 1.45 & 0.53 – 3.59 & 0.45 \\ \hline CA + AA & 1.50 & 1.07 – 2.11 & 0.02 & 1.25 & 0.79 – 1.97 & 0.33 \\ \hline rs6983267 \\ \hline TT & 1.0 & reference & & 1.0 & reference \\ \hline TG & 0.95 & 0.67 – 1.35 & 0.78 & 1.17 & 0.74 – 1.86 & 0.50 \\ \hline GG & 2.21 & 1.24 – 4.03 & 7.0 × 10-3 & 1.40 & 0.62 – 3.03 & 0.40 \\ \hline TG + GG & 1.12 & 0.80 – 1.57 & 0.50 & 1.21 & 0.78 – 1.88 & 0.41 \\ \hline Allele \\ \hline & \textbf{\textbf{OR*}} & 95\% CI & \textbf{\textbf{p value}} & \textbf{\textbf{OR*}} & 95\% CI & \textbf{\textbf{p value}} \\ \hline rs1447295 \\ \hline C & 1.0 & reference & & 1.0 & reference \\ \hline A & 1.34 & 1.01 – 1.79 & 0.04 & 1.23 & 0.84 – 1.79 & 0.29 \\ \hline rs6983267 \\ \hline T & 1.0 & reference & & 1.0 & reference \\ \hline G & 1.27 & 0.99 – 1.62 & 0.06 & 1.17 & 0.84 – 1.62 & 0.35 \\ \hline \end{tabular} \end{table}
PMC2719668_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & & \multicolumn{3}{c|}{\textbf{rs6983267}} \\ \hline & & \textbf{TT} & \textbf{TG} & \textbf{GG} \\ \hline rs1447295 & OR* & 1.0 & 0.78 & 1.69 \\ \hline \multirow{2}{*}{CC} & 95\% CI & reference & 0.50 – 1.23 & 0.78 – 3.75 \\ \hline OR* & 1.07 & 1.33 & 2.74 \\ \hline \multirow{2}{*}{CA} & 95\% CI & 0.58 – 1.94 & 0.77 – 2.29 & 1.13 – 7.17 \\ \hline OR* & 0.54 & 1.34 \\ \hline AA & 95\% CI & 0.15 – 1.81 & 0.42 – 4.48 \\ \hline \end{tabular} \end{table}
PMC2719668_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|} \hline & & & \multirow{2}{*}{\textbf{rs1447295 A allele frequency}} \\ \hline \\ \hline Author (Year) & N cases/N controls & Study population & Cases & Controls & OR & 95\% CI & p value \\ \hline \multirow{4}{*}{Amundadottir, et al. (2006)} & 1291/997 & Iceland & 0.17 & 0.11 & 1.72 & — & 1.7 × 10-9 \\ \hline 1435/779 & Sweden & 0.16 & 0.13 & 1.29 & — & 4.5 × 10-3 \\ \hline 458/247 & European Americans & 0.13 & 0.08 & 1.66 & — & 6.7 × 10-3 \\ \hline 246/352 & African Americans & 0.34 & 0.31 & 1.15 & — & 0.29 \\ \hline \multirow{5}{*}{Freedman, et al. (2006)} & 70/68 & Native Hawaiians & 0.37 & 0.16 & 3.02 & 1.66 – 5.50 & 1.5 × 10-4 \\ \hline 449/465 & Japanese Americans & 0.24 & 0.17 & 1.48 & 1.18 – 1.86 & 3.4 × 10-4 \\ \hline 640/567 & Latino Americans & 0.14 & 0.10 & 1.48 & 1.14 – 1.91 & 1.4 × 10-3 \\ \hline 455/447 & European Americans & 0.13 & 0.10 & 1.35 & 1.01 – 1.80 & 0.02 \\ \hline 989/804 & African Americans & — & — & 1.05 & 0.95 – 1.16 & 0.15 \\ \hline \multirow{2}{*}{Wang, et al. (2007)} & 491/545 & Caucasians & 0.12 & 0.10 & 1.16 & 0.85 – 1.58 & 0.25 \\ \hline 435/545 & Caucasians* & 0.17 & 0.10 & 1.93 & 1.37 – 2.72 & 4.0 × 10-3 \\ \hline \multirow{4}{*}{Gudmundsson, et al. (2007)} & 1453/3064 & Iceland & 0.17 & 0.10 & 1.71 & 1.49 – 1.95 & 1.6 × 10-14 \\ \hline 385/892 & Spain & 0.10 & 0.07 & 1.44 & 1.07 – 1.94 & 1.7 × 10-2 \\ \hline 367/1302 & The Netherlands & 0.14 & 0.11 & 1.39 & 1.09 – 1.78 & 9.0 × 10-3 \\ \hline 373/372 & African Americans & 0.32 & 0.31 & 1.01 & 0.81 – 1.25 & 0.96 \\ \hline \multirow{5}{*}{Haiman, et al. (2007)} & 1614/837 & African Americans & — & — & — & — & — \\ \hline 722/728 & Japanese Americans & — & — & — & — & — \\ \hline 111/112 & Native Hawaiians & — & — & — & — & — \\ \hline 637/633 & Latino Americans & — & — & — & — & — \\ \hline 1182/942 & European Americans & — & — & — & — & — \\ \hline Robbins, et al. (2007) & 490/567 & African Americans & 0.34 & 0.31 & 1.40 & 0.70 – 1.30 & 0.13 \\ \hline \multirow{3}{*}{Present study (2009)} & 391/323 & Native Japanese & 0.25 & 0.19 & 1.34 & 1.01 – 1.79 & 0.04 \\ \hline & & rs6983267 \\ \hline & & G allele frequency \\ \hline Author (Year) & N cases/N controls & Study population & Cases & Controls & OR & 95\% CI & p value \\ \hline \multirow{4}{*}{Amundadottir, et al. (2006)} & 1291/997 & Iceland & — & — & — & — & — \\ \hline 1435/779 & Sweden & — & — & — & — & — \\ \hline 458/247 & European Americans & — & — & — & — & — \\ \hline 246/352 & African Americans & — & — & — & — & — \\ \hline \multirow{5}{*}{Freedman, et al. (2006)} & 70/68 & Native Hawaiians & — & — & — & — & — \\ \hline 449/465 & Japanese Americans & — & — & — & — & — \\ \hline 640/567 & Latino Americans & — & — & — & — & — \\ \hline 455/447 & European Americans & — & — & — & — & — \\ \hline 989/804 & African Americans & — & — & — & — & — \\ \hline \multirow{2}{*}{Wang, et al. (2007)} & 491/545 & Caucasians & — & — & — & — & — \\ \hline 435/545 & Caucasians* & — & — & — & — & — \\ \hline \multirow{4}{*}{Gudmundsson, et al. (2007)} & 1453/3064 & Iceland & — & — & — & — & — \\ \hline 385/892 & Spain & — & — & — & — & — \\ \hline 367/1302 & The Netherlands & — & — & — & — & — \\ \hline 373/372 & African Americans & — & — & — & — & — \\ \hline \multirow{5}{*}{Haiman, et al. (2007)} & 1614/837 & African Americans & 0.90† & 0.84 & 1.43 & 1.17 – 1.75 & — \\ \hline 722/728 & Japanese Americans & 0.37† & 0.32 & 1.22 & 1.05 – 1.42 & — \\ \hline 111/112 & Native Hawaiians & 0.36† & 0.28 & 1.29 & 0.88 – 1.89 & — \\ \hline 637/633 & Latino Americans & 0.63† & 0.62 & 1.05 & 0.89 – 1.24 & — \\ \hline 1182/942 & European Americans & 0.54† & 0.51 & 1.13 & 0.99 – 1.28 & — \\ \hline Robbins, et al. (2007) & 490/567 & African Americans & 0.08 & 0.11 & 1.40 & 0.90 – 2.40 & 0.17 \\ \hline Present study (2009) & 391/323 & Native Japanese & 0.38 & 0.31 & 1.27 & 0.99 – 1.62 & 0.06 \\ \hline \end{tabular} \end{table}
PMC2719668_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{Strain} & \textbf{Serotype} & \textbf{Sequence source} & \textbf{LSPA6 lineage} & \textbf{SNP clade} & \textbf{Stx-phage insertion site genotype} \\ \hline EC4024 & O157:H7 & NZ_ABJT00000000 & I/II & 8 & 1 \\ \hline EC4042 & O157:H7 & NZ_ABHM00000000 & I/II & 8 & 1 \\ \hline EC4045 & O157:H7 & NZ_ABHL00000000 & I/II & 8 & 1 \\ \hline EC4076 & O157:H7 & NZ_ABHQ00000000 & I/II & 8 & 1 \\ \hline EC4113 & O157:H7 & NZ_ABHP00000000 & I/II & 8 & 1 \\ \hline EC4115 & O157:H7 & NZ_ABHN00000000 & I/II & 8 & 1 \\ \hline EC4196 & O157:H7 & NZ_ABHO00000000 & I/II & 8 & 1 \\ \hline EC4206 & O157:H7 & NZ_ABHK00000000 & I/II & 8 & 1 \\ \hline EC4401 & O157:H7 & NZ_ABHR00000000 & I/II & 8 & 1 \\ \hline EC4486 & O157:H7 & NZ_ABHS00000000 & I/II & 8 & 1 \\ \hline EC508 & O157:H7 & NZ_ABHW00000000 & I/II & 8 & 1 \\ \hline EC71074 & O157:H7 & Public Health Agency of Canada & I/II & 8 & 1 \\ \hline EC869 & O157:H7 & NZ_ABHU00000000 & II & uncertain & 6 \\ \hline EC4501 & O157:H7 & NZ_ABHT00000000 & I & 2 & 3 \\ \hline TW14588 & O157:H7 & NZ_ABKY00000000 & I & 2 & 3 \\ \hline EDL933 & O157:H7 & NC_002655.2 & I & 3 & 3 \\ \hline Sakai & O157:H7 & NC_002695.1 & I & 1 & 3 \\ \hline EC33264 & O145:NM & Public Health Agency of Canada & NA & NA & NA \\ \hline MG1655 & K12 & NC_000913.2 & NA & NA & NA \\ \hline \end{tabular} \end{table}
PMC2719669_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline Strain & Lineage & Strain & Lineage & Strain & Lineage \\ \hline AA10002 & I & H2727 & I & EC4113 & I/II \\ \hline AA10021 & I & H2731 & I & EC4115 & I/II \\ \hline APF593 & I & H432 & I & EC4196 & I/II \\ \hline 2328 & I & H435 & I & EC4206 & I/II \\ \hline 23339 & I & H4420 & I & EC4401 & I/II \\ \hline 58212 & I & H451 & I & EC4486 & I/II \\ \hline 63154 & I & H453 & I & EC508 & I/II \\ \hline 70490 & I & H454 & I & EC71074 & I/II \\ \hline 813601 & I & H568 & I & R1388 & I/II \\ \hline 93111 & I & H571 & I & Zap0046 & I/II \\ \hline 97701 & I & H572 & I & AA6192 & II \\ \hline EC4501 & I & H573 & I & AA9952 & II \\ \hline EC980120 & I & H574 & I & E12491 & II \\ \hline EC980121 & I & LN6374 & I & EC19920026 & II \\ \hline EC980122 & I & LRH6 & I & EC869 & II \\ \hline EC980125 & I & LRH73 & I & EC970520 & II \\ \hline EDL933 & I & LS110 & I & F1081 & II \\ \hline F1082 & I & LS236 & I & F12 & II \\ \hline F1095 & I & M01MD3265 & I & F1305 & II \\ \hline F1103 & I & OK1 & I & FRIK1985 & II \\ \hline F1299 & I & R1195 & I & FRIK1990 & II \\ \hline F2 & I & S23021 & I & FRIK1999 & II \\ \hline F30 & I & S2628 & I & FRIK2001 & II \\ \hline F5 & I & S3722 & I & FRIK920 & II \\ \hline F732 & I & Sakai & I & LRH13 & II \\ \hline F744 & I & TS97 & I & LS68 & II \\ \hline H2160 & I & TW14588 & I & R1797 & II \\ \hline H2161 & I & 09601Fe046.1 & I/II & 493/89 & O157:H- \\ \hline H2163 & I & 32511 & I/II & CB2755 & O157:H- \\ \hline H2164 & I & 59243 & I/II & Dec5d & O55:H7 \\ \hline H2176 & I & EC4024 & I/II & TB182A & O55:H7 \\ \hline H2704 & I & EC4042 & I/II & 5905 & O55:H7 \\ \hline H2718 & I & EC4045 & I/II & EC33264 & O145:NM \\ \hline H2723 & I & EC4076 & I/II & MG1655 & K12 \\ \hline \end{tabular} \end{table}
PMC2719669_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Number of proteins} & \textbf{1722} \\ \hline \textbf{Number of proteins} with OG & 1626 \\ \hline \textbf{Number of proteins} with a BP GO annotation (depth = 5) & 1026 \\ \hline \textbf{Number of proteins} with a CC GO annotation (depth = 5) & 688 \\ \hline \textbf{Number of proteins} with gene expression data & 1821 \\ \hline Number of interactions & 3035 \\ \hline Number of interactions with OG & 3032 \\ \hline Number of interactions between proteins with sufficient information on different genomic features & 1457 \\ \hline Number of interactions with a BP GO annotation (depth = 5, depth = 8) & 1457,157 \\ \hline Number of interactions with BP score > = 5, > = 8 & 913, 123 \\ \hline Number of interactions with a CC GO annotation (depth = 5) & 757 \\ \hline Number of interactions with CC score > = 5 & 565 \\ \hline Number of interactions with gene expression data & 2482 \\ \hline Number of interactions with PCC> = 0.3 & 837 \\ \hline Number of interactions with a BP GO annotation (depth = 5) and expression data & 1276 \\ \hline Number of interactions with BP score > = 5 and PCC > = 0.3) & 317 \\ \hline Total number of filtered interactions with CC score > = 5 or BP score > = 5 and PCC > = 0.3 or BP score > = 8) & 767 \\ \hline \end{tabular} \end{table}
PMC2719670_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline & \textbf{#proteins} & \textbf{#interactions} \\ \hline Yeast & 4662 & 175322 \\ \hline Yeast CC5 & 1182 & 9384 \\ \hline Yeast BP5+PCC 0.3 & 1249 & 8986 \\ \hline Yeast BP8 & 290 & 1336 \\ \hline Yeast total filtered & 1919 & 16145 \\ \hline Human & 3346 & 28397 \\ \hline Human CC5 & 694 & 1821 \\ \hline Human BP5+PCC 0.3 & 632 & 1082 \\ \hline Human BP8 & 185 & 421 \\ \hline Human total filtered & 1089 & 2795 \\ \hline C. elegans & 1549 & 4174 \\ \hline C. elegans CC5 & 149 & 199 \\ \hline C. elegans BP5+PCC 0.3 & 234 & 256 \\ \hline C. elegans BP8 & 70 & 100 \\ \hline C. elegans total filtered & 330 & 432 \\ \hline Drosophila & 3355 & 19315 \\ \hline Drosophila CC5 & 430 & 924 \\ \hline Drosophila BP5+PCC0.3 & 368 & 438 \\ \hline Drosophila BP8 & 87 & 140 \\ \hline Drosophila total filtered & 646 & 1282 \\ \hline All species – Interologs with CC annotation (CC > = 5) & 2123 (1431) & 43698 (11891) \\ \hline All species – Interologs with BP annotation (BP > = 5, BP > = 8) & 3087 (2111, 416) & 79475 (25037, 1890) \\ \hline All species – Interologs with gene expression data (PCC > = 0.3) & 5369 (4688) & 161928 (62178) \\ \hline All species – Filtered & 2233 & 18674 \\ \hline All species – Predicted & 3014 & 51885 \\ \hline All species – interologs (without filtering) & 6206 & 216972 \\ \hline \end{tabular} \end{table}
PMC2719670_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline & \multicolumn{2}{c|}{\textbf{23 DAP library}} & \multicolumn{2}{c|}{\textbf{35 DAP library}} & \multicolumn{2}{c|}{\textbf{Combined data}} \\ \hline \textbf{Category} & \textbf{\textbf{\textbf{Unique sequences}}} & \textbf{\textbf{\textbf{All sequences}}} & \textbf{\textbf{\textbf{Unique sequences}}} & \textbf{\textbf{\textbf{All sequences}}} & \textbf{\textbf{\textbf{Unique sequences}}} & \textbf{\textbf{\textbf{All sequences}}} \\ \hline Total extracted ditags & - & 34,984 & - & 15,919 & - & 50,903 \\ \hline Rejected ditags (Phred $\leq$ score 20a) & - & 10,685 & - & 3,306 & - & 13,991 \\ \hline Accepted ditags (Phred score > 20a) & 23,996 & 24,299 & 11,846 & 12,613 & 35,842 & 36,912 \\ \hline Total extracted tags & 24,655 & 48,534 & 12,714 & 25,198 & 37,369 & 73,732 \\ \hline Accepted tags (excluding polyA tags) & 24,654 & 48,514 & 12,713 & 25,183 & 37,367 & 73,697 \\ \hline \multicolumn{2}{c|}{Copy number of accepted} \\ \hline 1 & 18,183 (73.8.\%) & 18,183 (37.5\%) & 9,741 (76.6\%) & 9,741 (38.7\%) \\ \hline 2–5 & 5,329 (21.6\%) & 14,320 (29.5\%) & 2,510 (19.7\%) & 6,596 (26.2\%) \\ \hline 6–20 & 1,016 (4.1\%) & 9,450 (19.5\%) & 406 (3.2\%) & 3,668 (14.6\%) \\ \hline 21–99 & 118 (0.5\%) & 4,437 (9.1\%) & 46 (0.4\%) & 1,997 (7.9\%) \\ \hline >100 & 8 (0.03\%) & 2,124 (4.4\%) & 9 (0.07\%) & 3,181 (12.6\%) \\ \hline \end{tabular} \end{table}
PMC2719671_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{gene A. thaliana locus} & \textbf{Gene} & \textbf{Cumulated counts,35:23 DAP LongSAGE (non-normalized)} & \textbf{Fold-change 35:23 DAP LongSAGE (normalized)} & \textbf{Fold-change 35:23 DAP Real-time RT- PCR} & \textbf{EST B. napus contigs assembled by CAP3} \\ \hline AT2G40890 & Coumarate 3- hydroxylase (C3H) & 2:2 & 1.9 & 2.0 4.1 & Contig 1 from 5 ESTs Contig 2 from 2 ESTs \\ \hline AT5G48930 & Hydroxycinnamoyl- Coenzyme A shikimate/quinate hydroxycinnamoyl- transferase (HCT) & 5:3 & 3.2 & 2.3 & 1 EST \\ \hline AT1G15950 & Cinnamoyl-CoA reductase 1 (CCR1) & 2.2:1 & 4.3 & 0.9 & Contig from 4 ESTs \\ \hline AT2G23910 & Cinnamoyl-CoA reductase-related (CCR1-related) & 0:0 & - & 1.2 1.7 & Contig 1 from 22 ESTs Contig 2 from 13 ESTs \\ \hline AT3G19450 & Cinnamoyl alcohol dehydrogenase (CAD1) & 8:9.5 & 1.6 & 2.1 & Contig 3 from 4 ESTs \\ \hline AT4G27140 AT4G27150 AT4G27160 AT4G27170 & 2S seed storage proteins (napin) & 669.1:3.4 560.1:1.9 575.3:1.9 636.5:7.9 & 374.1 564.4 579.6 155.0 & 1224 & Contig from SAGE primer-amplified cloned 3'-terminal napin gene fragments \\ \hline \end{tabular} \end{table}
PMC2719671_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline \textbf{Rank} & \textbf{A. thaliana locus} & \textbf{No. of matched Brassica ESTs at 1e-6} & \textbf{No. of different tags matched to Brassica ESTs} & \textbf{Mean tag count per locus} & \textbf{Frequency of tag counts (\%, normalized)} & \textbf{Description of matched A. thaliana gene locus} \\ \hline 1 & AT5G45890 & 4,452 & 44 & 772 & 1.590 & SAG12 (SENESCENCE- ASSOCIATED GENE 12); cysteine-type peptidase \\ \hline 2 & AT5G50260 & 109 & 15 & 320 & 0.660 & cysteine proteinase, putative \\ \hline 3 & AT3G48350 & 14 & 7 & 299 & 0.615 & cysteine proteinase, putative \\ \hline 4 & AT5G38195 & 1,640 & 36 & 263 & 0.541 & protease inhibitor/seed storage/lipid transfer protein (LTP) family protein \\ \hline 5 & AT1G48750 & 8 & 4 & 209 & 0.430 & protease inhibitor/seed storage/lipid transfer protein (LTP) family protein \\ \hline 6 & AT3G20210 & 630 & 13 & 156 & 0.323 & DELTA-VPE (delta vacuolar processing enzyme); cysteine-type endopeptidasee \\ \hline 7 & AT2G12465 & 160 & 11 & 134 & 0.275 & LCR50 (Low-molecular-weight cysteine-rich 50) \\ \hline 8 & AT4G32110 & 852 & 20 & 127 & 0.263 & transferase, transferring glycosyl groups \\ \hline 9 & AT3G04120 & 814 & 30 & 124 & 0.256 & GAPC (GLYCERALDEHYDE-3- PHOSPHATE DEHYDROGENASE C SUBUNIT) \\ \hline 10 & AT5G37474 & 35 & 10 & 120 & 0.247 & Encodes a defensin-like (DEFL) family protein \\ \hline 11 & AT2G14846 & 191 & 13 & 118 & 0.244 & protease inhibitor/seed storage/lipid transfer protein (LTP) family proteinperoxidise \\ \hline 12 & AT4G21960 & 1,312 & 16 & 118 & 0.243 & PRXR1 (peroxidase 42); peroxidase \\ \hline 13 & AT5G60390 & 2,771 & 30 & 113 & 0.233 & elongation factor 1-alpha/ EF-1-alpha \\ \hline 14 & AT4G32105 & 79 & 13 & 109 & 0.225 & Galactosyltransferase \\ \hline 15 & AT1G58055 & 23 & 5 & 100 & 0.206 & Encodes a defensin-like (DEFL) family protein \\ \hline 16 & AT1G04645 & 502 & 11 & 97 & 0.200 & self-incompatibility protein- related \\ \hline 17 & AT1G05850 & 426 & 11 & 96 & 0.198 & POM1; chitinase \\ \hline 18 & AT1G08830 & 410 & 14 & 95 & 0.196 & CSD1 (copper/zinc superoxide dismutase 1) \\ \hline 19 & AT4G12960 & 351 & 6 & 93 & 0.191 & gamma interferon responsive lysosomal thiol reductase family protein/ GILT \\ \hline 20 & AT4G21650 & 53 & 8 & 92 & 0.189 & subtilase family protein \\ \hline \end{tabular} \end{table}
PMC2719671_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline \textbf{Rank} & \textbf{A. thaliana locus} & \textbf{No. of matched Brassica ESTs at 1e-6} & \textbf{No. of different tags matched to Brassica ESTs} & \textbf{Mean tag count per locus} & \textbf{Frequency of tag counts (\%, normalized)} & \textbf{Description of matched A. thaliana gene locus} \\ \hline 1 & AT4G27140 & 16,413 & 96 & 669 & 2.657 & 2S seed storage protein 1/ 2S albumin storage protein/NWMU1-2S albumin 1 \\ \hline 2 & AT4G27170 & 6,691 & 67 & 637 & 2.528 & 2S seed storage protein 4/ 2S albumin storage protein/NWMU2-2S albumin 4 \\ \hline 3 & AT4G27160 & 2,402 & 34 & 575 & 2.284 & 2S seed storage protein 3/ 2S albumin storage protein/NWMU2-2S albumin 3 \\ \hline 4 & AT4G27150 & 249 & 24 & 560 & 2.224 & 2S seed storage protein 2/ 2S albumin storage protein/NWMU2-2S albumin 2 \\ \hline 5 & AT4G28520 & 126 & 13 & 195 & 0.776 & CRU3 (CRUCIFERIN 3) \\ \hline 6 & AT3G27660 & 1,226 & 15 & 183 & 0.728 & OLEO4 (OLEOSIN4) \\ \hline 7 & AT5G38195 & 1,640 & 36 & 161 & 0.640 & protease inhibitor/seed storage/lipid transfer protein (LTP) family protein \\ \hline 8 & AT4G25140 & 1,119 & 15 & 146 & 0.580 & OLEO1 (OLEOSIN1) \\ \hline 9 & AT5G44120 & 1,112 & 17 & 143 & 0.567 & CRA1 (CRUCIFERINA); nutrient reservoir \\ \hline 10 & AT5G45890 & 4,452 & 44 & 143 & 0.566 & SAG12 (SENESCENCE- ASSOCIATED GENE 12); cysteine-type peptidase \\ \hline 11 & AT1G03880 & 1,791 & 12 & 138 & 0.549 & CRU2 (CRUCIFERIN 2); nutrient reservoir \\ \hline 12 & AT1G48750 & 8 & 4 & 136 & 0.538 & protease inhibitor/seed storage/lipid transfer protein (LTP) family protein \\ \hline 13 & AT1G79870 & 5 & 3 & 123 & 0.487 & oxidoreductase family protein \\ \hline 14 & AT1G12920 & 1 & 2 & 113 & 0.447 & ERF1-2 (EUKARYOTIC RELEASE FACTOR 1-2); translation release factor \\ \hline 15 & AT5G35530 & 401 & 6 & 102 & 0.406 & 40S ribosomal protein S3 (RPS3C) \\ \hline 16 & AT3G12580 & 31 & 8 & 102 & 0.405 & HSP70 (heat shock protein 70); ATP binding \\ \hline 17 & AT3G01570 & 170 & 6 & 99 & 0.393 & glycine-rich protein/ oleosin \\ \hline 18 & AT1G69830 & 1 & 2 & 97 & 0.385 & AMY3/ATAMY3 (ALPHA- AMYLASE-LIKE 3); alpha- amylase \\ \hline 19 & AT3G05020 & 401 & 14 & 86 & 0.340 & ACP1 (ACYL CARRIER PROTEIN 1) \\ \hline 20 & AT5G09440 & 31 & 3 & 82 & 0.326 & phosphate-responsive protein, putative \\ \hline \end{tabular} \end{table}
PMC2719671_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Locus} & \textbf{Number of alleles/ No. of individuals} & \textbf{No. polymorphic sites within PBR} \\ \hline Maeu-UM & 3/4 & 1 \\ \hline Maeu-UE & 2/4 & 0 \\ \hline Maeu-UK & 3/4 & 1 \\ \hline Maeu-UO & 2/4 & 0 \\ \hline Modo-UG & 12/16 & 2 \\ \hline \end{tabular} \end{table}
PMC2719672_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Gene} & \textbf{BAC location in wallaby} & \textbf{Location in opossum} & \textbf{Predicted location in wallaby} \\ \hline HNRPM & 3 & 3 & 4 [45] \\ \hline GPR128 & 5q (distal) & 4 & 5q (proximal) [44] \\ \hline ARPP19 & 7 & 1 & 7 [45] \\ \hline ARHGAP20 & 6 & 4 & 5 [45] \\ \hline \end{tabular} \end{table}
PMC2719672_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Class I locus} & \textbf{Primers} \\ \hline Maeu-UE & α1F – ATG TGC CTG CAG AAA GTG TCT GCG \\ \hline Primer set 1 & α2R – AT GGT TCA GGG CTC CTG AGT TCC \\ \hline Maeu-UK & α1F – AGT AGT TAG AGA GAC GGA GCA CAC \\ \hline Primer set 2 & α2R – GTA CTT CTG CAG CCA TTC AGT \\ \hline Maeu-UO & α1F – CAA GAG ATA CCA GAT TAC TGG GA \\ \hline Primer set 4 & α2R – CGT TCC CAG CGA TCC AAC TTA GA \\ \hline Maeu-UM & α1F – GCG GGC CCA GAC TGG GGT TAG AG \\ \hline Primer set 4 & α2R – ACG TTT AGG GCC ACG TTG TCC AAT \\ \hline MHC un-linked class I & α1F – CACTCCATGAGGTATTTCGACA \\ \hline Primer set 5 & α3R – GGCTCAGGCAGCCCCTCGTGC \\ \hline \end{tabular} \end{table}
PMC2719672_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{S.No} & \textbf{Complexes} & \textbf{Color} & \textbf{◦C Melting point} & \textbf{Mole Ratio} & \textbf{\% yield} \\ \hline 1 & Enoxacin & off white & 225 & — \\ \hline 2 & MnII complex & off white & 265d & 1 : 2 & 78 \\ \hline 3 & FeIII complex & dark brown & 275d & 1 : 1 & 70 \\ \hline 4 & NiII complex & leaf green & 246 & 1 : 2 & 76 \\ \hline 5 & CuII complex & light blue & 255 & 1 : 2 & 72 \\ \hline \end{tabular} \end{table}
PMC2719789_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|} \hline \textbf{S.\textbf{N}o} & \textbf{\textbf{C}ompound name} & & \textbf{C} & \textbf{H} & \textbf{N} & \textbf{C}hloride & \textbf{Metal} \\ \hline \multirow{2}{*}{1} & \multirow{2}{*}{Enoxacin} & Found & 56.42 & 5.85 & 16.99 & — & — \\ \hline \textbf{C}alculated & 56.24 & 5.35 & 17.49 \\ \hline \multirow{2}{*}{2} & \multirow{2}{*}{[Mn(eno)2(\textbf{H}2O)2]·3\textbf{H}2O} & Found & 45.40 & 6.12 & 14.04 & — & 7.05 \\ \hline \textbf{C}alculated & 45.90 & 5.92 & 14.34 & — & 6.99 \\ \hline \multirow{2}{*}{3} & \multirow{2}{*}{[Fe(eno)(\textbf{H}2O)2]·\textbf{C}l·4\textbf{H}2O} & Found & 33.67 & 5.27 & 10.47 & 13.2 & 10.43 \\ \hline \textbf{C}alculated & 33.73 & 5.20 & 10.58 & 13.5 & 10.24 \\ \hline \multirow{2}{*}{4} & \multirow{2}{*}{[\textbf{N}i(eno)2(\textbf{H}2O)2]·3\textbf{H}2O} & Found & 45.53 & 5.74 & 14.01 & — & 7.77 \\ \hline \textbf{C}alculated & 45.65 & 5.62 & 14.19 & — & 7.43 \\ \hline \multirow{2}{*}{5} & \multirow{2}{*}{[\textbf{C}u(eno)2(\textbf{H}2O)2]·3\textbf{H}2O} & Found & 45.39 & 5.56 & 14.12 & — & 8.02 \\ \hline \textbf{C}alculated & 45.37 & 5.58 & 14.11 & — & 8.00 \\ \hline \end{tabular} \end{table}
PMC2719789_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|l|l|l|} \hline \multirow{2}{*}{\textbf{Sample}} & \multirow{2}{*}{\textbf{Clostridium hofmani Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Staphylococcus aureus Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Bacillus subtilis Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Shigella flexneri Conc. (mg/disc)}} \\ \hline \\ \hline & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} \\ \hline Enoxacin & 8 & 14 & 16 & 8 & \textbf{\textbf{\textbf{\textbf{10}}}} & 14 & 8 & \textbf{\textbf{\textbf{\textbf{10}}}} & 12 & 8 & 11 & 13 \\ \hline Enox +Mn & \textbf{\textbf{\textbf{\textbf{10}}}} & 16 & \textbf{\textbf{\textbf{\textbf{20}}}} & 1\textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & 21 & 12 & 1\textbf{\textbf{\textbf{\textbf{5}}}} & 16 & 8 & 9 & 13 \\ \hline Enox + Fe & 8 & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & 7 & 9 & 11 & 7 & 8 & \textbf{\textbf{\textbf{\textbf{10}}}} \\ \hline Enox + Ni & 14 & 18 & 24 & 7 & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & 12 & 16 & \textbf{\textbf{\textbf{\textbf{10}}}} & 11 & 1\textbf{\textbf{\textbf{\textbf{5}}}} \\ \hline Enox + Cu & 11 & 13 & 17 & 14 & 1\textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & 11 & 11 & 8 & 11 & 12 \\ \hline \end{tabular} \end{table}
PMC2719789_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|l|l|l|} \hline \multirow{2}{*}{\textbf{Sample}} & \multirow{2}{*}{\textbf{Pseudomonas areuginosa Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Salmonella typhi Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Streptococcus pneumonia Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Citrobacter Conc. (mg/disc)}} \\ \hline \\ \hline & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} & \textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{20}}}} \\ \hline Enoxacin & 12 & 16 & 18 & 12 & 17 & 21 & 9 & 12 & 14 & \textbf{\textbf{\textbf{\textbf{10}}}} & 12 & 14 \\ \hline Enox +Mn & 9 & 12 & 1\textbf{\textbf{\textbf{\textbf{5}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & 1\textbf{\textbf{\textbf{\textbf{5}}}} & 18 & 9 & 12 & 14 & \textbf{\textbf{\textbf{\textbf{10}}}} & \textbf{\textbf{\textbf{\textbf{10}}}} & 11 \\ \hline Enox + Fe & 8 & 8 & \textbf{\textbf{\textbf{\textbf{10}}}} & 9 & \textbf{\textbf{\textbf{\textbf{10}}}} & 12 & 8 & \textbf{\textbf{\textbf{\textbf{10}}}} & 12 & \textbf{\textbf{\textbf{\textbf{10}}}} & 12 & 12 \\ \hline Enox + Ni & 13 & 18 & \textbf{\textbf{\textbf{\textbf{20}}}} & 11 & 17 & 22 & \textbf{\textbf{\textbf{\textbf{10}}}} & 12 & 22 & 14 & 1\textbf{\textbf{\textbf{\textbf{5}}}} & 18 \\ \hline Enox + Cu & \textbf{\textbf{\textbf{\textbf{10}}}} & 11 & 12 & 8 & 12 & 14 & 11 & 13 & 13 & 14 & 16 & 18 \\ \hline \end{tabular} \end{table}
PMC2719789_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline \multirow{2}{*}{\textbf{Sample}} & \multirow{2}{*}{\textbf{Escherichia coli Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Klebsiella pneumonia Conc. (mg/disc)}} & \multirow{2}{*}{\textbf{Proteus mirabilis Conc. (mg/disc)}} \\ \hline \\ \hline & \textbf{\textbf{\textbf{5}}} & \textbf{\textbf{\textbf{10}}} & \textbf{\textbf{\textbf{20}}} & \textbf{\textbf{\textbf{5}}} & \textbf{\textbf{\textbf{10}}} & \textbf{\textbf{\textbf{20}}} & \textbf{\textbf{\textbf{5}}} & \textbf{\textbf{\textbf{10}}} & \textbf{\textbf{\textbf{20}}} \\ \hline Enoxacin & 12 & 1\textbf{\textbf{\textbf{5}}} & 19 & 9 & 12 & 13 & \textbf{\textbf{\textbf{10}}} & 13 & 14 \\ \hline Enox +Mn & 12 & 13 & 14 & 11 & 11 & 12 & \textbf{\textbf{\textbf{10}}} & 11 & 13 \\ \hline Enox + Fe & \textbf{\textbf{\textbf{10}}} & 11 & 12 & 9 & 11 & 11 & 11 & 13 & 12 \\ \hline Enox + Ni & 14 & 16 & 2\textbf{\textbf{\textbf{5}}} & 11 & 14 & 18 & \textbf{\textbf{\textbf{10}}} & 12 & \textbf{\textbf{\textbf{20}}} \\ \hline Enox + Cu & \textbf{\textbf{\textbf{10}}} & 12 & 12 & \textbf{\textbf{\textbf{10}}} & 11 & 13 & 11 & 13 & 13 \\ \hline \end{tabular} \end{table}
PMC2719789_table_4
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{Group} & \textbf{Age} & \textbf{PMI} & \textbf{Cause of death} & \textbf{DSM-IV (six months diagnosis)} & \textbf{Toxicology screening} \\ \hline C & 51 & 15 & Motor vehicle accident & Alcohol dependence & Alcohol \\ \hline C & 31 & 24 & Cardiac arrest & Alcohol dependence \\ \hline C & 19 & 32 & Motor vehicle accident \\ \hline C & 47 & 12 & Cardiac arrest & Alcohol abuse \\ \hline C & 30 & 30 & Cardiac arrest \\ \hline C & 28 & 27 & Motor vehicle accident \\ \hline C & 41 & 24 & Myocardial Infarction \\ \hline C & 31 & 29.5 & Motor vehicle accident \\ \hline C & 46 & 19.5 & Myocardial Infarction \\ \hline C & 21 & 24 & Cardiac arrest \\ \hline C & 27 & 20.5 & Cardiac arrest \\ \hline C & 32 & 26.5 & Cardiac arrest & Cannabis abuse \\ \hline C & 55 & 24 & Motor vehicle accident \\ \hline S & 38 & 23 & Hanging & Alcohol dependence, cocaine dependence & Alcohol \\ \hline S & 21 & 21 & Asphyxiation & OCD, Alcohol dependence & Alcohol \\ \hline S & 31 & 32.5 & Hanging \\ \hline S & 29 & 26.5 & Hanging \\ \hline S & 33 & 18 & Hanging \\ \hline S & 26 & 69 & Hanging \\ \hline S & 30 & 27 & Stabbing & Paranoid schizophrenia \\ \hline S & 36 & 25 & Hanging \\ \hline S & 51 & 21 & Self inflicted gun shot & Alcohol dependence \\ \hline S & 42 & 27 & Carbon monoxide \\ \hline SMD & 28 & 20 & Hanging & MDD, alcohol dependence & Alcohol \\ \hline SMD & 22 & 11.5 & Hanging & MDD, alcohol dependence & Alcohol, cocaine \\ \hline SMD & 53 & 14 & Carbon monoxide & MDD \\ \hline SMD & 26 & 34 & Hanging & MDD & Cocaine \\ \hline SMD & 40 & 23 & Hanging & MDD, alcohol dependence \\ \hline SMD & 19 & 29.5 & Hanging & MDD \\ \hline SMD & 53 & 29 & Hanging & MDD, alcohol dependence \\ \hline SMD & 42 & 21 & Drowning & MDD & SSRI \\ \hline SMD & 45 & 20.5 & Self inflicted gun shot & MDD, pathological gambling \\ \hline SMD & 35 & 31 & Hanging & MDD, alcohol dependence \\ \hline SMD & 39 & 25.5 & Hanging & MDD \\ \hline SMD & 49 & 32 & Hanging & MDD, alcohol abuse \\ \hline SMD & 40 & 22 & Hanging & MDD \\ \hline SMD & 53 & 33.5 & Hanging & MDD \\ \hline SMD & 18 & 27 & Carbon monoxide & MDD \\ \hline SMD & 22 & 20 & Hanging & MDD \\ \hline \end{tabular} \end{table}
PMC2719799_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{Brain Region} & \textbf{Genes analyzed} & \textbf{Genes significant} & \textbf{\textbf{C-S}MD} & \textbf{C-S} & \textbf{SMD-S} \\ \hline BA4 (C = 6; S = 5; SMD = 8) & 14632 & 202 & 128 (66 up; 62 down) & 55 (28 up; 27 down) & 62 (35 up; 27 down) \\ \hline BA6 (C = 7; S = 6; SMD = 13) & 15266 & 286 & 216 (105 up; 111 down) & 76 (31 up; 45 down) & 46 (20 up; 26 down) \\ \hline BA8,9 (C = 6; S = 5; SMD = 9) & 14854 & 589 & 73 (33 up; 40 down) & 302 (71 up; 231 down) & 411 (147 up; 264 down) \\ \hline BA10 (C = 6; S = 6; SMD = 7) & 11935 & 636 & 604 (436 up; 168 down) & 41 (30 up; 11 down) & 69 (31 up; 38 down) \\ \hline BA11 (C = 6; S = 5; SMD = 9) & 14410 & 152 & 85 (19 up; 66 down) & 33 (11 up; 22 down) & 77 (50 up; 27 down) \\ \hline BA20 (C = 5; S = 5; SMD = 6) & 13944 & 255 & 77 (36 up; 41 down) & 68 (21 up; 47 down) & 173 (50 up; 123 down) \\ \hline BA21 (C = 9; S = 6; SMD = 5) & 14129 & 204 & 161 (42 up; 119 down) & 20 (8 up; 12 down) & 64 (37 up; 27 down) \\ \hline BA38 (C = 7; S = 5; SMD = 6) & 14395 & 182 & 65 (37 up; 28 down) & 102 (58 up; 44 down) & 64 (16 up; 48 down) \\ \hline BA24 (C = 7; S = 5; SMD = 9) & 15243 & 84 & 52 (27 up; 25 down) & 20 (5 up; 15 down) & 27 (15 up; 12 down) \\ \hline BA29 (C = 8; S = 7; SMD = 10) & 15032 & 83 & 19 (7 up; 12 down) & 40 (13 up; 27 down) & 40 (24 up; 16 down) \\ \hline Amy (C = 8; S = 6; SMD = 14) & 15007 & 153 & 95 (56 up; 39 down) & 47 (22 up; 25 down) & 35 (25 up; 10 down) \\ \hline Hippo (C = 6; S = 6; SMD = 10) & 14495 & 426 & 34 (16 up; 18 down) & 118 (60 up; 58 down) & 359 (196 up; 163 down) \\ \hline NAcc (C = 6; S = 6; SMD = 10) & 15232 & 140 & 22 (8 up; 14 down) & 60 (10 up; 50 down) & 91 (11 up; 80 down) \\ \hline BA44 (C = 12; S = 6; SMD = 13) & 15788 & 140 & 88 (32 up; 56 down) & 24 (15 up; 9 down) & 48 (30 up; 18 down) \\ \hline BA45 (C = 11; S = 6; SMD = 12) & 15886 & 101 & 60 (13 up; 47 down) & 21 (8 up; 13 down) & 27 (17 up; 10 down) \\ \hline BA46 (C = 7; S = 7; SMD = 12) & 15655 & 622 & 140 (37 up; 103 down) & 192 (148 up; 44 down) & 470 (373 up; 97 down) \\ \hline BA47 (C = 9; S = 7; SMD = 12) & 15303 & 163 & 102 (48 up; 54 down) & 29 (13 up; 16 down) & 51 (29 up; 22 down) \\ \hline Total & 251206 & 4472 \\ \hline \end{tabular} \end{table}
PMC2719799_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline \textbf{Category} & \textbf{Term} & \textbf{Count} & \textbf{\%} & \textbf{P-value} \\ \hline Biological Process & signal transduction & 237 & 41.73\textbf{\%} & 2.57E-37 \\ \hline Biological Process & intracellular signaling cascade & 138 & 24.30\textbf{\%} & 2.80E-42 \\ \hline Biological Process & cell organization and biogenesis & 132 & 23.24\textbf{\%} & 1.38E-24 \\ \hline Biological Process & protein localization & 79 & 13.91\textbf{\%} & 2.03E-25 \\ \hline Biological Process & protein transport & 77 & 13.56\textbf{\%} & 8.29E-26 \\ \hline Biological Process & establishment of protein localization & 77 & 13.56\textbf{\%} & 6.87E-25 \\ \hline Biological Process & transmission of nerve impulse & 61 & 10.98\textbf{\%} & 6.73E-25 \\ \hline Biological Process & small GTPase mediated signal transduction & 59 & 10.39\textbf{\%} & 1.54E-29 \\ \hline Biological Process & synaptic transmission & 57 & 10.03\textbf{\%} & 2.50E-22 \\ \hline Biological Process & vesicle-mediated transport & 55 & 9.68\textbf{\%} & 3.12E-20 \\ \hline \end{tabular} \end{table}
PMC2719799_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline & & \multicolumn{4}{c|}{\textbf{SemiQ RT-\textbf{\textbf{P}}CR (Mean)}} & \multicolumn{4}{c|}{\textbf{Affymetrix (Mean)}} \\ \hline \textbf{Gene} & \textbf{Region} & \textbf{\textbf{Control}} & \textbf{\textbf{Suicide}} & \textbf{\textbf{SMD}} & \textbf{\textbf{P}} & \textbf{\textbf{Control}} & \textbf{\textbf{Suicide}} & \textbf{\textbf{SMD}} & \textbf{\textbf{P}} \\ \hline GABARA\textbf{\textbf{P}}L1 & BA46 & 135.35 & 102.88 & 171.73 & 0.13 & 197.566 & 181.244 & 261.768 & 0.002 \\ \hline GABARD & BA45 & 70.96 & 49.53 & 69.86 & 0.04 & 265.784 & 190.645 & 273.365 & 0.002 \\ \hline GABARD & BA46 & 196.79 & 92.43 & 109.35 & 0.04 & 405.741 & 300.856 & 443.493 & 0.003 \\ \hline GABARG1 & BA21 & 64.17 & 85.35 & 61.89 & 0.13 & 262.739 & 215.787 & 170.116 & 0.002 \\ \hline GABARG1 & BA46 & 35.92 & 46.04 & 31.30 & 0.02 & 120.571 & 174.447 & 107.812 & 0.000 \\ \hline GABRG2 & BA46 & 52.95 & 36.15 & 48.91 & 0.04 & 416.956 & 267.694 & 418.698 & 0.007 \\ \hline GABRR1 & BA44 & 195.05 & 376.23 & 138.60 & 0.01 & 23.6967 & 35.345 & 19.1808 & 0.007 \\ \hline GLS & BA46 & 56.56 & 48.36 & 56.43 & 0.12 & 231.561 & 163.459 & 243.658 & 0.002 \\ \hline GLUL & Amy & 93.46 & 76.52 & 68.49 & 0.02 & 789.678 & 438.535 & 422.579 & 0.002 \\ \hline GLUL & BA21 & 131.67 & 118.04 & 107.04 & 0.08 & 463.524 & 442.932 & 265.696 & 0.002 \\ \hline GLUL & BA45 & 142.64 & 128.99 & 108.66 & 0.02 & 338.71 & 307.803 & 197.303 & 0.002 \\ \hline GLUL & BA46 & 128.30 & 184.69 & 87.91 & 0.01 & 251.503 & 361.113 & 190.146 & 0.001 \\ \hline GRIA1 & BA21 & 71.30 & 67.63 & 142.03 & 0.04 & 118.831 & 150.885 & 180.902 & 0.004 \\ \hline GRIA3 & BA46 & 82.77 & 48.63 & 51.32 & 0.05 & 132.681 & 93.5443 & 100.471 & 0.006 \\ \hline GRM3 & BA46 & 70.75 & 52.57 & 38.63 & 0.02 & 286.41 & 281.21 & 241.308 & 0.004 \\ \hline SLC6A1 & BA4 & 150.61 & 156.09 & 140.69 & 0.58 & 648.13 & 648.05 & 478.61 & 0.002 \\ \hline \end{tabular} \end{table}
PMC2719799_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline \textbf{Gene symbol} & \textbf{Gene name} & \textbf{FC microarray} & \textbf{qRT-PCR} & \textbf{DChip criteria} \\ \hline Insulin Signaling \\ \hline GAB1 & GRB2-associated binding protein 1 & 1.25 & Yes \\ \hline PIK3CA & Phosphoinositide-3-kinase, catalytic, alpha & 1.21 & Yes \\ \hline PIK3CB & Phosphoinositide-3-kinase, catalytic, beta & 1.25 \\ \hline PIK3R3 & Phosphoinositide-3-kinase, regulatory subunit 1 & 21.22 \\ \hline PIK3C3 & Phosphoinositide-3-kinase, class 3 & 1.21 \\ \hline TBC1D4 & TBC1 domain family, member 4 & 1.24 \\ \hline SORBS1 & Sorbin and SH3 domain containing 1 & 1.27 \\ \hline RHOQ & Ras homolog gene family, member Q & 1.27 \\ \hline SLC2A4 & Solute carrier family 2 member 4 (GLUT4) & 21.04 & Yes \\ \hline FOXO3A & Forkhead box O3 & 1.22 & Yes \\ \hline RPS6KB1 & Ribosomal protein S6 kinase, 70kDa, polypept. 1 & 1.30 \\ \hline SOS2 & Son of sevenless homolog 2 & 1.25 \\ \hline MAPK8 & Mitogen-activated protein kinase 8 & 1.23 \\ \hline MAP3K2 & Mitogen-activated protein kinase kinase kinase 2 & 1.23 \\ \hline MAP3K7 & Mitogen-activated protein kinase kinase kinase 7 & 1.21 \\ \hline MAP4K3 & Mitogen-act protein kinase kinase kinase kinase 3 & 1.24 \\ \hline RPS6KA3 & Ribosomal protein S6 kinase, 90kDa, polypeptide 3 & 1.21 \\ \hline \multicolumn{2}{c|}{Modulators of Insulin Action} \\ \hline PTPN11 & Protein tyrosine phosphatase, non-R type 11 & 1.23 \\ \hline MAPK8 & Mitogen-activated protein kinase 8 & 1.23 \\ \hline PRKAA2 & Protein kinase, AMP-act., alpha 2 catalytic subunit & 1.22 \\ \hline Metabolic Regulation \\ \hline HK2 & Hexokinase 2 & 21.42 & Yes \\ \hline LDHB & Lactate dehydrogenase B & 21.62 & Yes & Yes \\ \hline LPL & Lipoprotein lipase & 21.31 & Yes \\ \hline Mitochondrial Function \\ \hline PGC1a & PPARc coactivator 1a & 1.05 & Yes \\ \hline PGC1b & PPARc coactivator 1b & 21.18 & Yes \\ \hline HK2 & Hekokinase 2 & 21.42 & Yes \\ \hline Collagens \\ \hline COL1A1 & Collagen, type I, alpha 1 & 21.57 & Yes & Yes \\ \hline COL3A1 & Collagen, type III, alpha 1 & 21.53 & Yes & yes \\ \hline Miscellaneous \\ \hline TCF7L2 & Transcription factor 7-like 2 & 21.15 & Yes \\ \hline KIF1B & Kinesin family member 1B & 1.51 & Yes & Yes \\ \hline GDF8 & Growth differentiation factor 8 & 1.76 & Yes & Yes \\ \hline PDLIM5 & PDZ and LIM domain 5 & 1.63 & Yes & yes \\ \hline TncRNA & Trophoblast-derived noncoding RNA & 1.67 & & Yes \\ \hline GOLGA8A & Golgi autoantigen, golgin subfamily a, 8A & 1.57 & & Yes \\ \hline ARID5B & AT rich interactive domain 5B & 1.43 & & Yes \\ \hline LONRF2 & LON peptidase NT domain & ring finger 2 & 1.46 & & Yes \\ \hline \end{tabular} \end{table}
PMC2719801_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline \textbf{Pathway/function} & \textbf{Z-score} & \textbf{Permuted p-value} & \textbf{Adjusted p-value} \\ \hline First degree relatives \\ \hline Insulin signaling & 7.06 & ,0.001 & 0.005 & Upregulated \\ \hline TGF-b signaling & 6.25 & ,0.001 & 0.068 & Upregulated \\ \hline RNA splicing & 5.76 & ,0.001 & 0.089 & Upregulated \\ \hline Focal adhesion & 6.52 & ,0.001 & 0.140 & Downregulated \\ \hline Inorganic anion transport & 4.18 & 0.002 & 0.740 & Downregulated \\ \hline Inflammatory response pathway & 5.59 & 0.003 & 0.326 & Downregulated \\ \hline People with type 2 diabetes \\ \hline Apoptosis & 4.31 & ,0.001 & 0.388 & Upregulated \\ \hline Protein modification & 2.88 & 0.005 & 0.979 & Upregulated \\ \hline Cell cycle G1 to S control reactome & 3.47 & 0.006 & 0.676 & Upregulated \\ \hline Insulin signaling & 6.17 & ,0.001 & 0.002 & Downregulated \\ \hline MAPK signaling & 5.78 & ,0.001 & 0.002 & Downregulated \\ \hline G-protein signaling & 4.53 & ,0.001 & 0.078 & Downregulated \\ \hline \end{tabular} \end{table}
PMC2719801_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline & \textbf{Total Cells Counted} & \textbf{# Actin Polymerized} & \textbf{\% Actin Polymerized} \\ \hline WT & 443 & 402 & 90.7\% \\ \hline VavNULL & 427 & 51 & 11.9\% \\ \hline Vav1WT & 434 & 330 & 76.0\% \\ \hline Vav1GEF2 & 400 & 324 & 81.0\% \\ \hline \end{tabular} \end{table}
PMC2719804_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline & \textbf{Total Cells Counted} & \textbf{# MTOC Polarized} & \textbf{\% MTOC Polarized} \\ \hline WT & 197 & 167 & 84.7\% \\ \hline VavNULL & 195 & 77 & 39.5\% \\ \hline Vav1WT & 152 & 115 & 75.7\% \\ \hline Vav1GEF2 & 165 & 134 & 81.2\% \\ \hline \end{tabular} \end{table}
PMC2719804_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Drug Dose} & \textbf{Mean (Days)} & \textbf{Standard Error} \\ \hline Lithium \\ \hline 10 & 11.1 & 0.12 \\ \hline 1 & 14.6 & 0.15 \\ \hline 0.1 & 15.2 & 0.11 \\ \hline Control & 13.4 & 0.31 \\ \hline Valproic Acid \\ \hline 10 & 8.2 & 0.06 \\ \hline 1 & 11.3 & 0.15 \\ \hline 0.1 & 10.2 & 0.15 \\ \hline Control & 12.4 & 0.15 \\ \hline Theobromine \\ \hline 10 & 10.6 & 0.14 \\ \hline 1 & 12.1 & 0.44 \\ \hline 0.1 & 11.4 & 0.2 \\ \hline Control & 12.2 & 0.38 \\ \hline Caffeine \\ \hline 10 & 11.1 & 0.39 \\ \hline 1 & 12.2 & 0.88 \\ \hline 0.1 & 17.9 & 0.78 \\ \hline Control & 12.2 & 0.38 \\ \hline \end{tabular} \end{table}
PMC2719805_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{Supplement} & \textbf{Dose} & \multicolumn{2}{c|}{\textbf{Fraction mated to control}} & \multicolumn{2}{c|}{\textbf{p-value for significance tests}} \\ \hline & & \textbf{early} & \textbf{late} & \textbf{dose} & \textbf{dosage} \\ \hline \multirow{3}{*}{Caffeine} & 10 & 0.78 & 1 & ,0.00001 & ,0.00001 \\ \hline 1 & 0.75 & 0.97 & ,0.00001 & 0.00001 \\ \hline 0.1 & 0.68 & 0.86 & ,0.00001 & 0.006 \\ \hline \multirow{3}{*}{Valproic acid} & 10 & 0.75 & 1 & ,0.00001 & ,0.00001 \\ \hline 1 & 0.73 & 1 & ,0.00001 & ,0.00001 \\ \hline 0.1 & 0.7 & 1 & ,0.00001 & ,0.00001 \\ \hline \multirow{3}{*}{Lithium} & 10 & 0.97 & 1 & ,0.00001 & 0.11 \\ \hline 1 & 0.88 & 0.97 & ,0.00001 & 0.039 \\ \hline 0.1 & 0.82 & 0.98 & ,0.00001 & 0.0005 \\ \hline \multirow{3}{*}{Theobromine} & 10 & 0.68 & 0.76 & ,0.00001 & 0.38 \\ \hline 1 & 0.59 & 0.54 & 0.01 & 0.71 \\ \hline 0.1 & 0.51 & 0.43 & 0.56 & 0.42 \\ \hline \end{tabular} \end{table}
PMC2719805_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Variables} & \textbf{National Average and Range (Lowest and Highest Values)} \\ \hline Education index (2002) [44] & 0.82 (state range 0.74–0.90) \\ \hline Income index (2002) [44] & 0.74 (state range 0.59–0.90) \\ \hline Human development index (2004) [45] & 0.81 (state range 0.71–0.88) (municipal range 0.38–0.91) \\ \hline Households with access to water (2005) [3] & 94.5\% (state range 85.2–98.4) \\ \hline Life expectancy (2005) [22] & 73 y old for men, 77.9 y old for women (There is a 10-y difference in life expectancy between the poorest and richest groups.) \\ \hline Infant mortality rate (2004) [45] & 19.7 per 1,000 live births (state range 14.4–26.3) \\ \hline Maternal mortality rate (2005) [22] & 63.4 per 100,000 live births (state range 9.6–126.7) \\ \hline Mortality due to infectious diseases (preventable and avoidable if there is timely access to health care) [3] & In poor communities, 25\% of deaths for children ,5 y of age are due to infectious diseases; in affluent communities, the corresponding figure is 5\%. \\ \hline Health resources \\ \hline Per capita expenditure 2005 [22] & US$498 per capita (state range 316–1,103) \\ \hline Private health care expenditures 2005 (95\% out of pocket) [22] & 54\% of health expenditure is private (state range 28.5\%–76.5\%). In 2003 [41] health expenditures represented 8.5\% of income for lowest income decile and 2.6\% for the highest income decile \\ \hline Public health expenditure as percent of GDP (2006) [3] & 2.9\% of GDP (state range 2–8.2\%) \\ \hline Physicians per 1,000 population (2005) [22] & 1.9 (state range: 1–4) \\ \hline Beds per 1,000 population (2005) [22] & 1.1 (state range: 0.6–2.5) \\ \hline Nurses per 1,000 population (2005) [22] & 2.2 (state range: 1.3–4.6) \\ \hline \end{tabular} \end{table}
PMC2719806_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Functions} & \textbf{Public Social Security Schemes for Formal Sector Workers and Families} & \textbf{Uninsured} & \textbf{Affluent} \\ \hline \multirow{4}{*}{Responsibility for services and typical coverage of total population (percent varies each year according to employment conditions)} & IMSS for private formal sector employees 40\% & MoH 46\% & Private insurers 3\% \\ \hline ISSSTE for government employees 9\% \\ \hline SEDENA & SESMAR for armed forces 2\% \\ \hline Petro´leos Mexicanos (PEMEX) for oil workers less than 0.5\% \\ \hline Financing & Social Security schemes were financed from three sources: the employer, the government, and the employee. The proportions paid by each source were different for each scheme. & Government (mainly federal with some state contributions) & Private funds \\ \hline \multirow{2}{*}{Health care providers} & A network of clinics and hospitals staffed and operated by the different schemes & A network of clinics and hospitals staffed and operated by the MoH. Some states and municipalities had developed their own network. & Private network \\ \hline & The IMSS-COPLAMAR program, which was financed by the MoH and operated by the IMSS, provided health care mainly in rural areas. \\ \hline Access to services & Free at point of service (including medications) & Free at point of service (including medicines for priority programs) & Varied \\ \hline Per capita expenditure & Large variations depending on the type of scheme & Varied by state & Varied \\ \hline \end{tabular} \end{table}
PMC2719806_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Responsibility for Services} & \textbf{State Health System} \\ \hline Financing & Federal government, state governments, and user fees. States committed to increase their allocations to health, \\ \hline Health care providers & A network of state health services: all public facilities to be managed by the state health secretariats (including IMSS-COPLAMAR). Federal health employees refused to become state employees because salaries and fringe benefits tended to be lower. Labor unions refused to accept the decentralization. All state health workers were given the opportunity of becoming federal employees. Ironically, most workers at the state health secretariats are now federal employees \\ \hline Access to services & User fees for services and medicines. Medicines for priority programs were free. \\ \hline Per capita expenditure & Varied by state \\ \hline Devolution of decision-making power & Minimal: programs continued to be designed by MoH; states had very little control over financial resources (except for user fees). Personnel appointments continued to be made by MoH \\ \hline \end{tabular} \end{table}
PMC2719806_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Responsibility for Services} & \textbf{State Health System} \\ \hline Financing & Federal government, state governments, and user fees \\ \hline Health care providers & A network of state health services: all public facilities to be managed by the state health secretary. The majority of state employees became federal employees, states gained some control over human resources, programs, and finances \\ \hline Access to services & User fees for services and medicines. Medicines for priority programs were free. Attending physicians often waived fees for the indigent. \\ \hline Per capita expenditure & Varied by state \\ \hline \multirow{3}{*}{Devolution of decision-making power} & States obtained some control of personnel. In coordination with the state branch of the worker’s union, they could transfer and fire personnel, and recommend new federal hires. \\ \hline MoH transferred ownership of physical infrastructure to the states. \\ \hline The states were allowed ample discretionary power to spend federal transferred funds, except the funds allocated to human resources, although they were able to use the unspent personnel funds (due to absenteeism, leaves of absences) at their discretion. \\ \hline \end{tabular} \end{table}
PMC2719806_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Functions} & \textbf{Uninsured Not \textbf{Affiliated to SP} (Remains Basically Unchanged)} & \textbf{Affiliated to SP} \\ \hline Responsibility for services & State health system & State Health System. The System for Social Protection for Health (SSPH), also referred to as SP, decides the services to be provided to the insured, and the protocols to be followed \\ \hline \multirow{2}{*}{Financing} & Federal government, state governments, and user fees & The financing formula is very complicated. The MoH and the states make a fixed per family contribution. Enrolled families contribute to the system based on a sliding-fee scale. The federal government allocates extra funds to the most marginalized states. \\ \hline & Family premiums are waived for families in the lowest two income deciles and for those in the third lowest income decile with a child under 5 y. \\ \hline \multirow{2}{*}{Health care providers} & A network of state health services: all public facilities to be managed by the state health secretary. & States can decide, usually a network of private and public facilities and providers. \\ \hline The majority of state employees are federal employees; states have some control over human resources, programs, and finances & Often the state is unable to provide mandatory package of services and there is a need to contract with the private sector. \\ \hline \multirow{2}{*}{Access to services} & User fees for services and medicines. & Free at point of services (includes 312 medicines) \\ \hline Medicines for priority programs were free. Attending physicians often waived fees for the indigent. \\ \hline Per capita expenditure & Varied by state & Varies by state, but it is higher than for people unincorporated to SP who remain uninsured. \\ \hline \end{tabular} \end{table}
PMC2719806_table_4
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Variable} & \textbf{Category} & \textbf{Type} & \textbf{Character Variation} \\ \hline Gall hairiness & Morphology & Binary & Galls either have a smooth or hairy (defensive) surface. Labile. \\ \hline Gall spininess & Morphology & Binary & Galls are either spineless or covered with spines (defensive). Labile. \\ \hline Gall toughness & Morphology & Categorical & Four levels, increasing in toughness from 1 to 4. High toughness is defensive. Labile. \\ \hline Gall stickiness & Morphology & Binary & Galls are either coated with sticky resin (defensive) or not. Labile. \\ \hline Gall internal airspace & Morphology & Binary & Galls are either solid or have an internal airspace surrounding the larval chamber (defensive). Labile. \\ \hline Host gall size & Morphology & Continuous & The volume of each mature gall type, with gall inducer larval chamber subtracted. \\ \hline Host resource size & Resource availability & Continuous & The volume of each fully developed host gallwasp larva. \\ \hline Gall locularity & Resource availability & Binary & Galls either contain a single host gallwasp larva, or .1. Labile. \\ \hline Mean number of hosts/gall & Resource availability & Continuous & Mean number of parasitoids emerging from galls producing at least one parasitoid. \\ \hline Organ galled & Spatiotemporal niche & Categorical & Gall location on the oak host, either shoot bud, dormant bud on the trunk (lenticel), acorn, leaf, catkin, or shoot. Labile. \\ \hline Oak section & Spatiotemporal niche & Binary & Galls develop either on oaks in the section Cerris (Q. cerris) or in the section Quercus (Q. petraea, Q. robur)a. pubescens, and Q. Labile. \\ \hline Season of development & Spatiotemporal niche & Continuous & The week, starting at April 1st, that the gall was first observed to start development. \\ \hline Persistence & Spatiotemporal niche & Continuous & The mean duration of gall development, in weeks. \\ \hline Sample size & Sampling effort & Continuous & Total number of parasitoids emerging from galls of a given type. \\ \hline \end{tabular} \end{table}
PMC2719808_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Gall trait} & \textbf{Asexual} & \textbf{Sexual} \\ \hline Gall morphology \\ \hline Hairiness & — & — \\ \hline Toughness & (+) p,0.05 & — \\ \hline Spininess & p,0.01 (2) & — \\ \hline Stickiness & p,0.05 (2) & — \\ \hline Internal airspace & p,0.01 (2) & — \\ \hline Gall size & (+) p,0.01 & — \\ \hline Resource availability \\ \hline Host resource size & — & (+) p,0.001 \\ \hline Hosts/gall & — & — \\ \hline Locularity & — & — \\ \hline Spatiotemporal niche \\ \hline Plant organ galled & (+) p,0.001 & — \\ \hline Oak section & (+) p,0.001 & — \\ \hline Persistence & — & (+) p,0.001 \\ \hline Season & — & — \\ \hline \end{tabular} \end{table}
PMC2719808_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Variable} & \multicolumn{2}{c|}{\textbf{Dataset}} \\ \hline & \textbf{Asexual} & \textbf{Sexual} \\ \hline Sample size & 1 & — \\ \hline Relatedness (alone) & ***4 & * \\ \hline Relatedness in MAM & 1 & — \\ \hline Gall morphology \\ \hline Hairiness & *2 & — \\ \hline Toughness & — & — \\ \hline Spininess & *1 & N/A \\ \hline Stickiness & ** \\ \hline 6Internal airspace & — & N/A \\ \hline Gall size & *2 & 1 \\ \hline Resource availability \\ \hline Host size & 1 & — \\ \hline Locularity & — & 1 \\ \hline Hosts/gall & *2 & *1 \\ \hline Spatiotemporal niche \\ \hline Plant organ galled & ***2 & * \\ \hline Oak section & **3 & **1 \\ \hline Season & *1 & — \\ \hline Persistence & — & ***1 \\ \hline \end{tabular} \end{table}
PMC2719808_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline SNP-43 & G/G & G/A & A/A & P \\ \hline Calpain-10 expression & 1.0060.18 (16) & 1.3360.22 (11) & 1.2060.37 (4) & 0.32 \\ \hline secretion1 Basal insulin & 0.03460.0028 (20) & 0.03960.0035 (13) & 0.04460.0056 (5) & 0.066 \\ \hline GSIS1 & 0.07260.013 (20) & 0.08860.016 (13) & 0.1060.026 (5) & 0.0222 \\ \hline Glucose SI & 1.9160.25 (20) & 2.2360.31 (13) & 2.4360.49 (5) & 0.042 \\ \hline Arginine SI & 1.8760.16 (18) & 2.1560.19 (12) & 1.5560.33 (4) & 0.13 \\ \hline Glibenclamide SI & 2.0460.26 (19) & 2.2660.33 (12) & 1.8360.65 (3) & 0.25 \\ \hline SNP-44 & T/T & T/C & C/C & P \\ \hline Calpain-10 expression & 1.1860.14 (26) & 1.0360.32 (5) & 0.42 (1) & 0.582 \\ \hline secretion1 Basal insulin & 0.03760.002 (30) & 0.03360.005 (6) & 0.0360.009 (2) & 0.452 \\ \hline GSIS1 & 0.08460.011 (30) & 0.0660.024 (6) & 0.0560.04 (2) & 0.272 \\ \hline Glucose SI & 2.2160.21 (30) & 1.7160.47 (6) & 1.6760.81 (2) & 0.342 \\ \hline Arginine SI & 2.0060.14 (25) & 1.5260.28 (6) & 2.1560.48 (2) & 0.09 \\ \hline Glibenclamide SI & 2.0460.23 (25) & 1.9060.57 (6) & 2.8560.57 (2) & 0.98 \\ \hline \end{tabular} \end{table}
PMC2719809_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{\textbf{Gene} Ontology Biological Process at Level 6} & \textbf{Gene} & Uni\textbf{Gene} Accession & Percentage of \textbf{Gene}s & \multicolumn{2}{c|}{\textbf{Z-ratios}} \\ \hline & & & & \textbf{PA6-DA} & \textbf{MM55K} \\ \hline \multirow{8}{*}{Neurogenesis} & IDB4 & NM_031166.1 & 5.88 & 3.16 & 2.57 \\ \hline EFNB1 & NM_010110.2 & & 8.56 & 7.43 \\ \hline CXCL12 & NM_013655.2 & & 16.27 & 14.34 \\ \hline TIMP2 & NM_011594.2 & & 3.32 & 1.66 \\ \hline MYH10 & NM_009382.2 & & 9.62 & 5.18 \\ \hline THY1 & NM_175260.1 & & 3.15 & 2.90 \\ \hline RUNX1 & NM_009821.1 & & 4.28 & 4.71 \\ \hline NOTCH1 & NM_008714.2 & & 3.02 & 3.99 \\ \hline \multirow{5}{*}{Central nervous system development} & OTX1 & NM_011023.2 & 3.68 & 3.22 & 2.04 \\ \hline IDB4 & NM_031166.1 & & 3.16 & 2.57 \\ \hline CXCL12 & NM_013655.2 & & 16.27 & 14.34 \\ \hline MYH10 & NM_175260.1 & & 3.15 & 2.90 \\ \hline NOTCH1 & NM_008714.2 & & 3.02 & 3.99 \\ \hline \multirow{5}{*}{Tissue development} & MGLAP & NM_008597.2 & 3.68 & 9.42 & 1.40 \\ \hline PTN & NM_008973.1 & & 13.50 & 14.60 \\ \hline SOX9 & NM_011448 & & 11.62 & 6.33 \\ \hline OTOR & NM_020595 & & 4.04 & 4.61 \\ \hline NOTCH1 & NM_008714.2 & & 3.02 & 3.99 \\ \hline \multirow{4}{*}{Wnt receptor signaling pathway} & SFRP1 & NM_013834.1 & 2.94 & 14.24 & 14.53 \\ \hline SFRP2 & NM_009144.1 & & 3.16 & 3.09 \\ \hline FRZB & NM_011356.2 & & 3.44 & 2.56 \\ \hline PPAP2B & NM_080555.1 & & 3.37 & 7.36 \\ \hline \multirow{4}{*}{Cellular morphogenesis during differentiation} & EFNB1 & NM_010110.2 & 2.94 & 8.56 & 7.43 \\ \hline CXCL12 & NM_013655.2 & & 16.23 & 14.34 \\ \hline THY1 & NM_009382.2 & & 9.62 & 5.18 \\ \hline NOTCH1 & NM_008714.2 & & 3.02 & 3.99 \\ \hline \multirow{3}{*}{Neural crest cell differentiation} & EFNB1 & NM_010110.2 & 2.21 & 8.56 & 7.43 \\ \hline SEMA3F & NM_011349.2 & & 4.66 & 0.40 \\ \hline SOX9 & NM_011448 & & 11.62 & 6.33 \\ \hline \multirow{2}{*}{Regulation of cell migration} & CXCL12 & NM_013655.2 & 2.21 & 16.23 & 14.34 \\ \hline THY1 & NM_009382.2 & & 9.62 & 5.18 \\ \hline \multirow{2}{*}{Cell fate specification} & SOX9 & NM_011448 & 2.21 & 11.62 & 6.33 \\ \hline NOTCH1 & NM_008714.2 & & 3.02 & 3.99 \\ \hline Neural tube development & LTAP & NM_033509.2 & 0.74 & 3.21 & 2.18 \\ \hline \end{tabular} \end{table}
PMC2719871_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline \textbf{Genes} & \textbf{UniGene Accession} & \multicolumn{5}{c|}{\textbf{Z-ratios}} \\ \hline & & \textbf{PA6-DA/PA6-X} & \textbf{PA6-DA/PA6-X}1 & \textbf{PA6-DA/MS5} & \textbf{PA6-DA/MM55K} & \textbf{PA6-DA/MEF} \\ \hline CXCL12 & NM 013655.2 & 16.27 & 16.92 & 15.08 & 14.34 & 9.96 \\ \hline EFNB1 & NM 010110.2 & 8.56 & 9.26 & 8.40 & 7.43 & 7.01 \\ \hline PTN & NM 008973.1 & 13.50 & 14.58 & 12.17 & 14.60 & 5.70 \\ \hline IGF-II & NM 010514.1 & 13.19 & 13.83 & 11.63 & 13.52 & 3.28 \\ \hline IGFBP4 & NM 010517.2 & 14.18 & 13.39 & 12.70 & 12.50 & 5.73 \\ \hline \end{tabular} \end{table}
PMC2719871_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline & \textbf{H. sapiens} & \textbf{C. elegans} & \textbf{\% conserved} & \textbf{Studied by RNAi} \\ \hline Total CI subunits & 45 & 38 & 84\% & 28 \\ \hline mtDNA-encoded & 7 & 7 & 100\% & 0 \\ \hline \multirow{2}{*}{nDNA-encoded} & 38 & 31 predicted in silico & 82\% & 28 \\ \hline & (26 confirmed by BNG) \\ \hline Subcomplex of nDNA subunits \\ \hline Il & 15 & 14 & 93\% & (+2)* 13 \\ \hline Ia alone & 8 & 5 & 63\% & 4 \\ \hline Ia, Ib & 2 & 2 & 100\% & 2 \\ \hline Ib & 11 & 10 & 91\% & 9 \\ \hline Ic** & 1 & 0 & 0\% & 0 \\ \hline undefined*** & 1 & 0 & 0\% & 0 \\ \hline CI Assembly Factors & 4 & 4 & 100\% & 2 \\ \hline \end{tabular} \end{table}
PMC2719872_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline \textbf{Gene} & \textbf{Accession number} & \textbf{Protein coded} & \textbf{Forward primer (59–39)} & \textbf{Reverse Primer (59–39)} \\ \hline GRP78 & M19645 & BiP & CCTGGGTGGCGGAACCTTCGATGTG & CTGGACGGGCTTCATAGTAGACCGG \\ \hline GADD153 & S40706 & CHOP & GCCTTTCTCCTTTGGGACACTGTCCAGC & CTCGGCGAGTCGCCTCTACTTCCC \\ \hline HAMP & NM_021175 & Hepcidin & ATGGCACTGAGCTCCCAGAT & TTCTACGTCTTGCAGCACATCC \\ \hline CEBPA & NM_004364 & C/EBPa & CTAGAGATCTGGCTGTGGGG & TCATAACTCCGGTCCCTCTG \\ \hline SLC40A1 & NM_014585 & Ferroportin & CCCGGAGACAAGTCCTGAATC & TGGCCCATTGCCACAAAGGAG \\ \hline FTH1 & AF088851 & Ferritin H & CAGAACTACCACCAGGACTCAGA & TAGCCCGAGGCTTAGCTTTCA \\ \hline ALB & NM_000477 & Albumin & CAAAAACATGTGTTGCTGATGA & CTTGTTTTGCACAGCAGTCAG \\ \hline GAPDH & NM_002046 & GADPH & GAAGGTGAAGGTCGGAGTC & GAAGATGGTGATGGGATTTC \\ \hline \end{tabular} \end{table}
PMC2719873_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|l|l|} \hline \multicolumn{4}{c|}{\textbf{4-residue \textbf{\textbf{\textbf{Loop}}}s}} & \multicolumn{4}{c|}{\textbf{8-residue \textbf{\textbf{\textbf{Loop}}}s}} & \multicolumn{4}{c|}{\textbf{12-residue \textbf{\textbf{\textbf{Loop}}}s}} \\ \hline \textbf{\textbf{\textbf{Loop}}} & \textbf{\textbf{\textbf{SOS}}} & \textbf{\textbf{\textbf{CSJD}}} & \textbf{\textbf{\textbf{CCD}}} & \textbf{\textbf{\textbf{Loop}}} & \textbf{\textbf{\textbf{SOS}}} & \textbf{\textbf{\textbf{CSJD}}} & \textbf{\textbf{\textbf{CCD}}} & \textbf{\textbf{\textbf{Loop}}} & \textbf{\textbf{\textbf{SOS}}} & \textbf{\textbf{\textbf{CSJD}}} & \textbf{\textbf{\textbf{CCD}}} \\ \hline 1dvjA_20 & 0.23 & 0.38 & 0.61 & 1cruA_85 & 1.48 & 0.99 & 1.75 & 1cruA_358 & 2.39 & 2.00 & 2.54 \\ \hline 1dysA_47 & 0.16 & 0.37 & 0.68 & 1ctqA_144 & 1.37 & 0.96 & 1.34 & 1ctqA_26 & 2.54 & 1.86 & 2.49 \\ \hline 1eguA_404 & 0.16 & 0.36 & 0.68 & 1d8wA_334 & 1.18 & 0.37 & 1.51 & 1d4oA_88 & 2.44 & 1.60 & 2.33 \\ \hline 1ej0A_74 & 0.16 & 0.21 & 0.34 & 1ds1A_20 & 0.93 & 1.30 & 1.58 & 1d8wA_46 & 2.17 & 2.94 & 4.83 \\ \hline 1i0hA_123 & 0.22 & 0.26 & 0.62 & 1gk8A_122 & 0.96 & 1.29 & 1.68 & 1ds1A_282 & 2.33 & 3.10 & 3.04 \\ \hline 1id0A_405 & 0.33 & 0.72 & 0.67 & 1i0hA_122 & 1.37 & 0.36 & 1.35 & 1dysA_291 & 2.08 & 3.04 & 2.48 \\ \hline 1qnrA_195 & 0.32 & 0.39 & 0.49 & 1ixh_106 & 1.21 & 2.36 & 1.61 & 1eguA_508 & 2.36 & 2.82 & 2.14 \\ \hline 1qopA_44 & 0.13 & 0.61 & 0.63 & 1lam_420 & 0.90 & 0.83 & 1.60 & 1f74A_11 & 2.23 & 1.53 & 2.72 \\ \hline 1tca_95 & 0.15 & 0.28 & 0.39 & 1qopB_14 & 1.24 & 0.69 & 1.85 & 1qlwA_31 & 1.73 & 2.32 & 3.38 \\ \hline 1thfD_121 & 0.11 & 0.36 & 0.50 & 3chbD_51 & 1.23 & 0.96 & 1.66 & 1qopA_178 & 2.21 & 2.18 & 4.57 \\ \hline Average & 0.20 & 0.40 & 0.56 & Average & 1.19 & 1.01 & 1.59 & Average & 2.25 & 2.34 & 3.05 \\ \hline \end{tabular} \end{table}
PMC2719875_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \multirow{2}{*}{\textbf{organ/tissue}} & \multirow{2}{*}{\textbf{silica-NPs (red)(a)}} & \multirow{2}{*}{\textbf{polystyrene-NPs (a) (YG)}} & \multirow{2}{*}{\textbf{polystyrene-NPs (a) (YO, carboxy)}} \\ \hline \\ \hline pharynx - lumen & +(b) & + & + \\ \hline intestine - lumen & + & + & + \\ \hline intestine - tissue & 2 & + & + \\ \hline proximal gonad & 2 & + & + \\ \hline spermatheca & 2 & 2 & + \\ \hline early embryo/cytoplasm & 2 & 2 & + \\ \hline \end{tabular} \end{table}
PMC2719910_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline & \textbf{Septic Subjects (n = 40)} \\ \hline Age (years) & 56.862.43 \\ \hline Sex (\% Female) & 35\% \\ \hline APACHE II & 17.161.04 \\ \hline SOFA & 6.760.7 \\ \hline Mechanical Ventilation (\%) & 42.5 \\ \hline Vasopressors (\%) & 65 \\ \hline Bactermia (\%) & 37.5 \\ \hline 28 Day Mortality (\%) & 17.5 \\ \hline \end{tabular} \end{table}
PMC2719911_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Sample duration} & \textbf{‘No rotation’ condition} & \textbf{‘Rotation’ condition} \\ \hline 100 ms & .50/.13 & .43/.23 \\ \hline 1,000 ms & .59/.12 & .45/.26 \\ \hline 2,000 ms & .63/.10 & .57/.21 \\ \hline 3,000 ms & .76/.09 & .55/.28 \\ \hline \end{tabular} \end{table}
PMC2719912_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline & \textbf{Stimuli Type} & \textbf{0 colored squares} & \textbf{2 colored squares} & \textbf{4 colored squares} & \textbf{6 colored squares} \\ \hline \multirow{2}{*}{0 geons} & geons & N/A & N/A & N/A & N/A \\ \hline colored squares & N/A & .96/.03 & .94/.17 & .89/.28 \\ \hline \multirow{2}{*}{1 geon} & geons & .97/.13 & .82/.17 & .97/.17 & .80/.17 \\ \hline colored squares & N/A & .98/.03 & .90/.23 & .77/.45 \\ \hline \multirow{2}{*}{2 geons} & geons & .93/.21 & .92/.23 & .77/.30 & .83/.12 \\ \hline colored squares & N/A & .98/.05 & .85/.22 & .92/.30 \\ \hline \multirow{2}{*}{3 geons} & geons & .83/.13 & .80/.18 & .88/.42 & .75/.20 \\ \hline colored squares & N/A & .97/.08 & .92/.15 & .85/.28 \\ \hline \end{tabular} \end{table}
PMC2719912_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Condition} & \textbf{Hits/FAs} \\ \hline Task 1: Different viewpoints & .66/.35 \\ \hline Task 2: Different viewpoints & .51/.38 \\ \hline Task 1: Same viewpoints & .76/.31 \\ \hline Task 2: Same viewpoints & .45/.12 \\ \hline Task 1: Different viewpoints & .77/.38 \\ \hline Task 2: Same viewpoints & .53/.20 \\ \hline Task 1: Same viewpoints & .71/.14 \\ \hline Task 2: Different viewpoints & .56/.30 \\ \hline \end{tabular} \end{table}
PMC2719912_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Condition} & \textbf{Hits/FAs} \\ \hline Task 1: Different basic-level category & .86/.28 \\ \hline Task 2: Different basic-level category & .63/.06 \\ \hline Task 1: Same basic-level category & .79/.28 \\ \hline Task 2: Same basic-level category & .56/.06 \\ \hline Task 1: Different basic-level category & .90/.31 \\ \hline Task 2: Same basic-level category & .56/.11 \\ \hline Task 1: Same basic-level category & .80/.29 \\ \hline Task 2: Different basic-level category & .66/.08 \\ \hline \end{tabular} \end{table}
PMC2719912_table_3
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|} \hline \textbf{Cell line} & \textbf{Cell Type} & \textbf{Source/Reference} & \textbf{Karyotype/Notes} \\ \hline human dermal fibroblast (HDF) & primary neonatal foreskin fibroblasts & ATCC & 46,XY \\ \hline HT1080 & fibrosarcoma & ATCC & 46,XY/92,XXYY \\ \hline LT690 & lymphoblastoid & Ref. 15 & 46,XY \\ \hline t60-12 (somatic cell hybrid 1) & mouse-human hybrid; L cell derived & Ref.42 & contains single human active X chromosomes \\ \hline Aha-11aB1 (somatic cell hybrid 2) & mouse-human hybrid; L cell derived & Ref. 42 & contains single human active X chromosome \\ \hline HTM18TC8 & hamster-human hybrid & Refs. 21, 22 & contains single human X chromosome \\ \hline FA3Wg8-4 & hamster-human hybrid & Refs. 21, 22 & truncated X chromosome from HTM18TC8 line \\ \hline \end{tabular} \end{table}
PMC2719913_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{Genomic site} & \textbf{primer name} & \textbf{description} & \textbf{length} & \textbf{Position Assembly March 2006} & \textbf{Ta} \\ \hline ZXDA & BS254/255 & F: 59 TCAATTAAGGTGGGAGGCAG 39 R: TGTGAGGTAATTATGGCAAAGTC 39 & 217 bp & chrX:57949717-57949933 & 59uC \\ \hline 1 (Xp sat jxn) & BS236/237 & F: 59 ATTTTCCCAGCACCATTTTTCAA 39 R: 59 CTGTCAAGATGGTATGGGCTGTGT 39 & 397 bp & chrX:58104524-58104920 & 56uC \\ \hline 2 (HSAT4) & BS392/393 & F: 59 TGTGGTCAGCGAGATGTCTC 39 R: 59 AGTTTCCTGTGTGACCCCAG 39 & 159 bp & chrX:58259011-58259169 & 64uC \\ \hline 3 (HSAT4-c jxn) & BS222/223 & 59 39 59 F: CCAGGCATTCAAGCGGGAGAG R: CGGCGGAAGTTATCGTTGAGAG 39 & 355 bp & chrX:58296350-58296704 & 60uC \\ \hline 4 (c-satellite) & BS160/161 & F: 59 TTC AAC GTA CCC CTG AAA GCC TGG 39 R: 59 CTA TTT TGT CCC AAG CCT GCC 39 & 339 bp & chrX:58329603-58329941 & 58uC \\ \hline 5 (c-ALR jxn) & BS226/227 & 59 39 59 F: AGCCCGAGGAAAATACTGGTGAGG R: GCTGTCTTTCTAGTTTTTGTCGTGGGTTAT 39 & 224 bp & chrX:58335817-58336040 & 62uC \\ \hline 6 (Xp mono-HOR jxn) & BS240/241 & F: 59 AACGCTGCGCTATCAAAGGGAAAGT 39 R: 59 39 GGACATGTGGAGCGCTTTGTGC & 313 bp & chrX:58577182-58577494 & 64uC \\ \hline 7 (a-satellite) & BS13/14 & F: 59 ATAATTTCCCATAACTAAACACA 39 R: 59 TGTGAAGATAAAGGAAAAGGCTT 39 & 535 bp & chrX:61610033-61610567 & 55uC \\ \hline 8 (Xq HOR-mono jxn) & BS258/259 & F: 59 GACCTCAAAGCACTCTAAATACAC 39 R: 59 39 CTTCACATAAAAACTAGACAGACAG & 495 bp & chrX:61642633-61643127 & 61uC \\ \hline 9 (Xq sat jxn) & BS238/239 & F: 59 CCTGCTGAATCAAAACAATGGT 39 R: 59 CAAAGAAGGCTGGGTGAGAAG 39 & 389 bp & chrX:61962313-61962701 & 59uC \\ \hline jxn+150 10 (Xq kb) & BS260/261 & F: 59 TGCCTCCATGATTCAGTTACCA 39 R: 59 AATCTCCCTCCTCTTACCCTCTA 39 & 475 bp & chrX:62111658-62112132 & 58uC \\ \hline \end{tabular} \end{table}
PMC2719913_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline \multirow{2}{*}{\textbf{ID}} & \multirow{2}{*}{\textbf{Mission}} & \multirow{2}{*}{\textbf{Role*}} & \multirow{2}{*}{\textbf{Last Name}} & \multirow{2}{*}{\textbf{Mass{ kg}} & \multirow{2}{*}{\textbf{Height{ m}} & \multirow{2}{*}{\textbf{L1 m}} \\ \hline \\ \hline 1 & 11 & CDR & Armstrong & 76.2 & 1.80 & 0.97 \\ \hline 2 & 11 & LMP & Aldrin & 75.5 & 1.78 & 0.96 \\ \hline 3 & 12 & CDR & Conrad & 66.8 & 1.69 & 0.91 \\ \hline 4 & 12 & LMP & Bean & 66.3 & 1.77 & 0.95 \\ \hline 5 & 14 & CDR & Shepard & 76.4 & 1.80 & 0.97 \\ \hline 6 & 14 & LMP & Mitchell & 80.1 & 1.80 & 0.97 \\ \hline 7 & 15 & CDR & Scott & 79.6 & 1.83 & 0.99 \\ \hline 8 & 15 & LMP & Irwin & 72.0 & 1.73 & 0.93 \\ \hline 9 & 16 & CDR & Young & 77.2 & 1.75 & 0.95 \\ \hline 10 & 16 & LMP & Duke & 71.8 & 1.82 & 0.98 \\ \hline 11 & 17 & CDR & Cernan & 78.2 & 1.83 & 0.99 \\ \hline 12 & 17 & LMP & Schmidt & 73.9 & 1.75 & 0.95 \\ \hline \end{tabular} \end{table}
PMC2719915_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|} \hline \textbf{Gene} & \textbf{Probeset ID} & \textbf{SNP (LCL)} & \textbf{P-value (LCL)} & \textbf{SNP (HOb)} & \textbf{P-value (HOb)} & \textbf{Replicated in HObs?} \\ \hline Cep192 & 3779862 & rs482360 & 3.71E-19 & rs570505 & 4.22E-03 & No \\ \hline ZNF83 & 3869658 & rs1012531 & 2.72E-10 & rs1012531 & 5.39E-02 & Yes \\ \hline C17orf57 & 3724617 & rs3760372 & 5.54E-12 & rs3760372 & 4.29E-01 & No \\ \hline CAST & 2821249 & rs7724759 & 7.17E-16 & rs13362120 & 4.73E-13 & Yes \\ \hline CD46 & 2377476 & rs4844390 & 1.06E-14 & rs2761437 & 6.02E-02 & Yes \\ \hline FLJ10241 & 3863093 & rs1043413 & 9.38E-11 & rs3810174 & 1.15E-03 & Yes \\ \hline LRAP & 2821389 & rs2255546 & 8.37E-22 & rs2161657 & 8.39E-01 & Yes \\ \hline POMZP3 & 3057764 & rs2005354 & 3.77E-22 & rs17718122 & 1.70E-10 & No \\ \hline ULK4 & 2670619 & rs1717020 & 5.99E-11 & rs9852303 & 1.45E-05 & Yes \\ \hline PARP2 & 3527423 & rs2297616 & 2.81E-37 & rs3093942 & 4.94E-07 & Yes \\ \hline ATPIF1 & 2327383 & rs2481974 & 4.26E-11 & rs8559 & 1.70E-01 & No \\ \hline MRPL43 & 3303658 & rs12241232 & 1.24E-11 & rs3740487 & 2.44E-05 & Yes \\ \hline DKFZp451M2119 & 2588913 & rs10930785 & 1.93E-28 & rs10930785 & 1.56E-09 & Yes \\ \hline RNH1 & 3358076 & rs11821392 & 4.34E-15 & rs12420868 & 4.88E-01 & Yes \\ \hline SNX11 & 3725089 & rs7224014 & 4.20E-09 & rs2240122 & 1.47E-01 & No \\ \hline USMG5 & 3304753 & rs7911488 & 2.66E-24 & rs1163073 & 6.45E-11 & Yes \\ \hline SEP15 & 2421300 & rs1407131 & 7.57E-13 & rs17452535 & 1.01E-02 & Yes \\ \hline SLC35B3 & 2941033 & rs3799255 & 2.12E-10 & rs3799255 & 1.30E-02 & Yes \\ \hline DERP6 & 3708382 & rs2521985 & 2.55E-13 & rs222851 & 6.18E-04 & Yes \\ \hline ARTS-1 & 2868133 & rs7705827 & 6.09E-19 & rs1862609 & 3.98E-06 & Yes \\ \hline TAP2 & 2950168 & rs3763355 & 1.98E-13 & rs241448 & 4.48E-01 & No \\ \hline IRF5 & 3023264 & rs6969930 & 8.27E-22 & rs10239340 & 8.94E-01 & Yes \\ \hline PPIL2 & 3938301 & rs5999098 & 1.46E-12 & rs5754727 & 1.54E-02 & Yes \\ \hline PTER & 3236819 & rs1055340 & 5.25E-18 & rs7909832 & 6.24E-13 & No \\ \hline WARS2 & 2430765 & rs1325933 & 3.53E-08 & rs1325933 & 6.38E-01 & Yes \\ \hline \end{tabular} \end{table}
PMC2719916_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline \textbf{GO CATEGORY} & \textbf{Total Genes} & \textbf{Changed Genes} & \textbf{Enrichmentt} & \textbf{LOG10(p)} \\ \hline GO:0008283_cell_proliferation & 507 & 58 & 1.47 & 22.86 \\ \hline GO:0012501_programmed_cell_death & 425 & 67 & 2.03 & 28.15 \\ \hline GO:0006915_apoptosis & 423 & 67 & 2.04 & 28.24 \\ \hline GO:0007249_I-kappaB_kinase_NF-kappaB_cascade & 104 & 20 & 2.48 & 23.94 \\ \hline GO:0045595_regulation_of_cell_differentiation & 64 & 12 & 2.41 & 22.48 \\ \hline GO:0007259_JAK-STAT_cascade & 31 & 8 & 3.32 & 22.70 \\ \hline GO:0042509_regulation_of_tyrosine_phosphorylation_of_STAT_protein & 10 & 4 & 5.15 & 22.29 \\ \hline GO:0042771_DNA_damage_response__signal_transduction_by_p53_class_ mediator_resulting_in_induction_of_apoptosis & 5 & 3 & 7.73 & 22.38 \\ \hline \end{tabular} \end{table}
PMC2720376_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|} \hline \textbf{GO CATEGORY} & \textbf{Total Genes} & \textbf{Changed Genes} & \textbf{Enrichmentt} & \textbf{LOG10(p)} \\ \hline GO:0046907_intracellular_transport & 282 & 53 & 1.56 & 23.32 \\ \hline GO:0006892_post-Golgi_vesicle-mediated_transport & 14 & 7 & 4.16 & 23.25 \\ \hline GO:0006099_tricarboxylic_acid_cycle & 7 & 4 & 4.76 & 22.27 \\ \hline GO:0046356_acetyl-CoA_catabolic_process & 7 & 4 & 4.76 & 22.27 \\ \hline GO:0009081_branched_chain_family_amino_acid_metabolic_process & 6 & 5 & 6.94 & 23.87 \\ \hline \end{tabular} \end{table}
PMC2720376_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Gene Symbol} & \textbf{Description} & \textbf{RT-PCR Ratio AR ChIP/IgG ChIP} \\ \hline GSK3B & Glycogen synthase kinase 3 beta & 3.03 \\ \hline OR9Q1 & Olfactory receptor, family 9, subfamily Q, member 1 & 25.03 \\ \hline TADA2L & Transcriptional adaptor 2 (ADA2 homolog, yeast)-like & 3.26 \\ \hline ZNF533 & Zinc finger protein 533 & 3.26 \\ \hline ARL16 & ADP-ribosylation factor-like 16 & 0.79 \\ \hline \end{tabular} \end{table}
PMC2720376_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|} \hline \textbf{Toxidrome} & \textbf{Site of Action} & \textbf{Signs and symptoms} \\ \hline Opioid & opioid receptor & sedation, miosis, decreased bowel sounds, decreased respirations \\ \hline Anticholinergic & muscurinic acetylcholine receptors & altered mental status, sedation, hallucinations, mydriasis, dry skin, dry mucous membranes, decreased bowel sounds and urinary retention \\ \hline Sedative-hypnotic & gamma-aminobutyric acid receptors & sedation, normal pupils, decreased respirations \\ \hline Sympathomimetic & alpha and beta adrenergic receptors & agitation, mydriasis, tachycardia, hypertension, hyperthermia, diaphoresis \\ \hline Cholinergic & nicotinic and muscurinic acetylcholine receptors & altered mental status, seizures, miosis, lacrimation, diaphoresis, bronchospasm, bronchorrhea, vomiting, diarrhea, bradycardia \\ \hline Serotonin syndrome & serotonin receptors & altered mental status, tachycardia, hypertension, hyperreflexia, clonus, hyperthermia \\ \hline \end{tabular} \end{table}
PMC2720377_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Toxic alcohols} & \textbf{Ethanol} \\ \hline & Isopropanol \\ \hline & Methanol \\ \hline & Ethylene Glycol \\ \hline \multirow{5}{*}{Drugs/Additives} & Isoniazid \\ \hline Mannitol \\ \hline Propylene glycol \\ \hline Glycerol \\ \hline Osmotic contrast dyes \\ \hline \multirow{3}{*}{Other Chemicals} & Ethyl ether \\ \hline Acetone \\ \hline Trichloroethane \\ \hline \end{tabular} \end{table}
PMC2720377_table_1
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|} \hline \textbf{Agent or Clinical Finding} & \textbf{Potential Antidote(s)} \\ \hline Acetaminophen & N-acetylcysteine \\ \hline Benzodiazapines & Flumazenil \\ \hline Beta blockers & Glucagon \\ \hline Cardiac glycosides & Digoxin immune Fab \\ \hline Crotalid envenomation & Crotalidae polyvalent immune Fab \\ \hline Cyanide & Hydroxocobalamin \\ \hline Ethylene glycol & Fomepizole \\ \hline Iron & Deferoxamine \\ \hline Isoniazid & Pyridoxine \\ \hline Lead & Succimer Dimercaprol Calcium ethylenediamine tetra-acetic acid \\ \hline Methanol & Fomepizole \\ \hline Methemoglobinemia & Methylene blue \\ \hline Monomethylhydrazine Mushrooms & Pyridoxime \\ \hline Opioids & Naloxone \\ \hline Organophosphates & Atropine Pralidoxime \\ \hline Sulfonylureas & Glucose Octreotide \\ \hline \end{tabular} \end{table}
PMC2720377_table_2
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|} \hline \textbf{Author} & \textbf{Sample} & \multicolumn{4}{c|}{\textbf{Attitude & Knowledge}} \\ \hline & & \textbf{Scores range} & \textbf{Pre (M, SD)} & \textbf{Post (M, SD)} & \textbf{Statistical sig.} \\ \hline \multirow{3}{*}{Shahmohamadi, 1991} & Behvarz: \\ \hline (Experimental) & 0–50 & 22.96 $\pm$ 47.73 & 40.81 $\pm$ 11.08 & t = 11.65* \\ \hline (Control) & & 24.87 $\pm$ 21.66 & 28.64 $\pm$ 18.9 & p < 0.01 \\ \hline \multirow{3}{*}{Bolhari, 1995} & Behvarz: \\ \hline (Experimental) & 0–29 & 17.68 $\pm$ 2.84 & 21.09 $\pm$ 2.37 & t = 5.63* \\ \hline (Control) & & 16.4 $\pm$ 2.78 & 17.65 $\pm$ 2.03 & p < 0.01 \\ \hline \multirow{4}{*}{Kadivar, 1997} & Karshenas & 0–20 & 6.2 $\pm$ 2.9 & 12 $\pm$ 5.1 & p < 0.05** \\ \hline Kardan & 0–20 & 6.2 $\pm$ 2.9 & 12.6 $\pm$ 4.1 \\ \hline Behvarz & 0–20 & 3.6 $\pm$ 2.7 & 10.8 $\pm$ 3.7 \\ \hline Behdashtyar & 0–20 & 5.3 $\pm$ 2.4 & 13.6 $\pm$ 3.4 \\ \hline \end{tabular} \end{table}
PMC2720378_table_0
\begin{table} \centering \label{tab:tablelabel} \begin{tabular}{|l|l|l|l|l|l|l|l|l|l|} \hline \textbf{Study} & & \multicolumn{4}{c|}{\textbf{Knowledge}} & \multicolumn{4}{c|}{\textbf{Attitude}} \\ \hline \textbf{Author} & \textbf{Sample} & \textbf{\textbf{Before M (SD)}} & \textbf{\textbf{After M (SD)}} & \textbf{\textbf{Score Range}} & \textbf{\textbf{Statistical sig.}} & \textbf{\textbf{Before M (SD)}} & \textbf{\textbf{After M (SD)}} & \textbf{\textbf{Score Range}} & \textbf{\textbf{Statistical sig.}} \\ \hline Motallebi, 1996 & Behvarz & 15.43(5.04) & 32.52(2.84) & 0–38 & t = 30.99 p < 0.01 & 8.39(2.23) & 12.58(1.41) & 0–26 & t = 16 p < 0.01 \\ \hline \multirow{4}{*}{Davasaz, 2004} & General population \\ \hline Experimental & 36.36(8.4) & 46.9(4.78) & 0–58 & F = 107.26 & 6.29(5.7) & 14.51(3.36) & 0-22 & F = 56.43 \\ \hline Control 1* & 32.73(8.85) & 35.96(5.44) & 0–51 & df = 2,270 & 6.36(4.04) & 6.65(3.67) & & df = 2,264 \\ \hline Control 2* & 32.04(6.68) & 30.94(4.44) & 0–42 & p < 0.0001 & 4.43(3.01) & 5.20(2.79) & & P < 0.0001 \\ \hline \multirow{3}{*}{Bolhari, 1995} & General population \\ \hline Experimental & - & - & - & - & 14.33(2.87) & 14.7(3.07) & 0-22 & t = 2.21** p < 0.05 \\ \hline Control & & & & & 14.44(2.91) & 14(3.04) \\ \hline \multirow{3}{*}{Shahmohammadi, 1990} & General population \\ \hline Experimental & - & - & - & - & 18.79(22.27) & 23.12(24.34) & 0–30 & t = 9.44** p < 0.01 \\ \hline Control & & & & & 18.25(22.75) & 20.18(28.75) \\ \hline \end{tabular} \end{table}
PMC2720378_table_1