The South Orient Rail Line is a state-owned facility that runs from Presidio, on the Mexican border, to San Angelo Junction. It was constructed to interchange with Ferromex at Presidio, but the Presidio-Ojinaga International Rail Bridge is not currently operational.

The line interchanges with Union Pacific Railroad at Alpine and with BNSF Railway and the Fort Worth and Western Railroad at San Angelo Junction. Texas Pacifico Transportation Ltd. (TXPF) operates over the South Orient Rail Line under a lease and operating agreement with TxDOT.
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