jeffreygwang/pythia_dedupe_mia_49975-49990_50000-98500

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You will understand the relationships between power, privilege, and systems of oppression. Sometimes, this will overwhelm you, but I hope it never drowns out your faith in humanity. I hope you understand the worst of humanity but believe in its best. Don’t worry these are just a few of my hopes and dreams for you. I haven’t figured all of the things on this list out, but that’s why you’re here. My only real hope is that you are better than me, that this life and this world seem kinder somehow. The Black Student Alliance Invitational (BSAI) is a four-day event on campus for prospective students that identify as Black. The weekend is filled with exciting events that enable the prospective students to experience many facets of the college experience. I was lucky enough to attend this event last March. Now that I work at the Mary Lou Williams Center for Black Culture, the center that sponsors the event, as well as am a co-chair of one of the planning committees, I cherish my memories of BSAI even more. My first day at BSAI, I arrived at Duke and got to meet my host, whom I instantly had a connection with. I also met a girl who is now my best friend at Duke. The rest of the day evolved into a night of bowling, and the rest of the weekend turned into a time I’ll never forget. My BSAI experience came just days after an African American student had been harassed by a racist chant performed by a fraternity on campus. The community’s willingness to discuss the incident, and not shy away from it, was inspiring. The discussion of racial issues was something new to me, which I appreciated and was comforted by. I am from a predominately white community where others recognizing my Blackness was almost unheard of. The best I got was a "Black History Month" prayer by our school’s resident nun. It wasn’t until I came to BSAI that I realized that there are people that actually look like me, think like me, and live the struggle like me. Finding that comfort solidified my decision to attend Duke. I truly believe that without the opportunity to attend BSAI many students would not have the ability to experience what it is like to be on Duke's campus, and possibly not end up choosing to enroll at Duke. Allowing students to spend the weekend here greatly influences their decision to enroll at Duke. Being a top ten university, the majority of students that apply, and are accepted to Duke, also apply, and are accepted, to other top schools. The biggest deciding factor, in my opinion, in attending any institution, is the experience that one has on campus. I believe that the experience that one has at BSAI separates Duke from the rest. I can never be anything less than grateful for the experience that BSAI provided me. It allowed me to establish a foundation on this campus. This foundation has flourished into a job as an Abele Ambassador at the Marylou Williams Center, and an active member of the black community on campus. Alexandria Miller, History and African American Studies Major, class of 2017 As part of the Students of the Caribbean Association, we have been gearing up for our best Caribbean Awareness Week yet. This year, we’ll bring back returning treats like a traditional steel pan band and a Monday Motivations collaboration with the Center for Multicultural Affairs. This year will also bring about new traditions including a keynote speaker and will culminate with our annual Caribana festival. It goes without saying that Caribbean Awareness Week is, at least in my opinion, the most wonderful time of the year! Being able to celebrate my Caribbean heritage has been one of the most significant attributes of my college experience. From our annual J’ouvert celebration till four in the morning, debating Caribbean politics, or discussing how society misinterprets new songs in our Caribbean dialects, there has been no greater family to me here than my fellow Caribbean and Caribbean-American friends here. If you are from the Caribbean or just want to get to know more about Caribbean culture, I encourage you to join SOCA this year for Caribbean Awareness Week 2016 from Thursday, March 24th through Friday, April 1st this year and follow us on social media @DukeSOCA to stay up-to-date! There will be tons of food, great music, and even greater people! We hope to see you there! In recent years, more and more Black women are wearing their natural hair unapologetically; and it’s beyond beautiful. After decades of straightening, chemically altering and manipulating our curls to fit a beauty standard that wasn’t ours, we have started to love and appreciate our curls, kinks and coils. Due to the positivity of this movement, many black women have also embraced their looks and learned to love themselves and recognize their beauty. There is more representation of Black women in media, and there are more cosmetic companies that cater to Black women. Due to the magnitude of this movement, Black women’s hair and appearance has become a highly politicized aspect of our lives. One of these conversations is based on the professionalism (or lack thereof) of Black women’s hair. A little over a month ago, Lara Oddoffin had her job revoked because her braids were not “professional” enough. The company emailed her stating, “If you are unable to take them out I unfortunately won't be able to offer you any work.” Many other women have been criticized for sporting their natural curls and afros. How is the hair that grows out of my scalp not deemed acceptable? Why do I have to succumb to a white standard of beauty and professionalism to be accepted? Or even land a job? Why does my decision to wear my hair exactly the way it grows deemed “bold” or even considered a movement? Why does my hair somehow define me? Despite the over politicized discussion of Black women’s hair, many people still embrace the natural hair movement. But, while there has been a lot of positive impact of the natural hair movement, we often fail to recognize the few failures of the movement. Whether it is in media or on social network, whenever we’re appreciating and promoting the beauty of Black women, we tend to focus on women who are close in line with the white beauty standard. Women who have fairer skin, softer curls and thin figures are the ones most people think of when it comes to beauty in the Black community. We use Black celebrities to claim our celebration of Black beauty, when in reality, we somehow internalize and Idealize values for Eurocentric beauty standards even within our own community. Zola Ndlovy of wordpress.com perfectly puts it as, “In the economy that is black beauty, being light skinned is a social currency.” Or in this context, reflecting beauty standards that resemble white beauty standards is the social currency. This is not even what is most problematic. The big issue is how we fail to see the diversity of our beauty. The fact that we differentiate between what constitutes an “acceptable” type of Black woman and what doesn’t, is a huge problem. The fact that we rarely see Black women who don’t have light skin, a thin figure, and “nice hair” just shows how narrow our society’s thinking is when it comes to the beauty of Black women. Phrases like “…cute for a black girl,” or “…too black” emphasize the negative stigma that already exists in the politicized world of Black beauty, yet they’re things we continue to hear day to day. The challenge is to recognize the diverseness of Black women, while redefining what beauty means, and shifting it away from internalized hatred for our own physical features; it is knowing that if we say “black is beautiful”, we truly do mean all of our blackness is beautiful, not just the parts that look “acceptable”. After all, beauty is not hair, or skin or figure. Beauty is knowing one’s identity and self worth. Whether it is your natural curls, your kinky fro, or your relaxed hair, what constitutes your beauty is so much more than just the surface. For any Black adult who has ever been to college, more than likely some of the pivotal snapshots of our college careers are linked to the events and programs that were held by members of the National Pan-Hellenic Council (NPHC). Whether it be one of their academic enrichment programs, neophyte presentations or infamous step shows and parties, we sometimes frame our college years around these unique African-American organizations. Too often though, we take these organizations and their many contributions for granted, seeing them as a prop to our collegiate experiences. But, what if we took the mundane seriously? What if black constructions of brotherhood and sisterhood were actually works of art? And, what if the traditions emanating from Black Greek letter organizations were also works of art too? As such, this two-part exhibit begs all of its onlookers to consider the NPHC experience in a way that elevates it to art. “Divine” asks us to consider NPHC interactions as art. “Movement” on the other hand, asks us to consider stepping as both iconography and artistic. Join me in a consideration of “Divine Movement.” Black History Month 2016 has been one to remember. From Black Hollywood standing together through the #OscarsSoWhite hashtag to voice their discontentment with the lack of Black nominees for the second straight year, to Beyonce’s electric pro-Black performance at the Super Bowl, to Kendrick Lamar’s breathtaking performance at
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48, 1532, 49, 1532, 51, 1532, 50, 187, 187, 1898, 309, 452, 4425, 326, 253, 1390, 495, 34588, 651, 320, 1805, 745, 751, 436, 27, 187, 187, 11717, 50276, 34, 1532, 35, 1532, 36, 187, 50261, 61, 187, 24594, 14, 18, 50269, 46, 1532, 47, 1532, 48, 187, 50254, 50275 ]	in Pretoria, the local government and housing department in Gauteng said on Thursday. The houses were handed over on the spot on Tuesday to the legitimate beneficiaries after the department successfully evicted the illegal occupants, said spokesperson Motsamai Motlhaolwa. “At least 50 houses and 273 stands were illegally occupied, thus creating a delay in the continuation of the project in the area to build houses for beneficiaries,” said Motlhaolwa. A partnership between the department, the City of Tshwane and the community established that some houses and stands were sold to illegal occupants and foreign nationals by people claiming to be community leaders. MEC Ntombi Mekgwe welcomed the positive and quick response by the department in dealing with the crisis. She said the issue had become a major problem for the department and committed that her department will continue to work hard to deal with such lawlessness. “We cannot allow this to become a norm. We will continue to use all available avenues to ensure that illegal occupation does not happen under our watch,” said Mekgwe. She said the move should be a warning to would-be illegal occupants. “Beneficiaries have been waiting patiently for their houses and I urge others to follow the correct procedures and await their turn.” The department had began with its preparations to evict the illegal occupants of the 273 stands to allow the contractor to continue with the construction of more houses. - Sapa// Copyright 2016 The Chromium Authors. All rights reserved. // Use of this source code is governed by a BSD-style license that can be // found in the LICENSE file. #ifndef SKIA_EXT_TEXTURE_HANDLE_H_ #define SKIA_EXT_TEXTURE_HANDLE_H_ #include "third_party/skia/include/gpu/gl/GrGLTypes.h" namespace skia { // TODO(bsalomon): Remove both of these conversions when Skia bug 5019 is fixed. inline GrBackendObject GrGLTextureInfoToGrBackendObject( const GrGLTextureInfo& info) { return reinterpret_cast<GrBackendObject>(&info); } inline const GrGLTextureInfo* GrBackendObjectToGrGLTextureInfo( GrBackendObject object) { return reinterpret_cast<const GrGLTextureInfo>(object); } } // namespace skia #endif // SKIA_EXT_TEXTURE_HANDLE_H_ ; Copyright (C) 2013 Apple Inc. All rights reserved. ; ; Redistribution and use in source and binary forms, with or without ; modification, are permitted provided that the following conditions ; are met: ; 1. Redistributions of source code must retain the above copyright ; notice, this list of conditions and the following disclaimer. ; 2. Redistributions in binary form must reproduce the above copyright ; notice, this list of conditions and the following disclaimer in the ; documentation and/or other materials provided with the distribution. ; ; THIS SOFTWARE IS PROVIDED BY APPLE INC. AND ITS CONTRIBUTORS ``AS IS'' ; AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, ; THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR ; PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL APPLE INC. OR ITS CONTRIBUTORS ; BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR ; CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF ; SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS ; INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN ; CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ; ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF ; THE POSSIBILITY OF SUCH DAMAGE. (webkit-powerbox) (shared-preferences-read-write "com.apple.quicktime.plugin.preferences") (allow file-read file-write* (home-library-subpath "/Caches/QuickTime") (home-library-preferences-literal "/QuickTime Preferences")) (allow network-bind (local ip)) Does anyone currently assign TI-Nspires or other calculators to their students like a textbook at the beginning of the year? If yes, do they have a document or district policy on it that you can share? Any tips, pros or cons?Revista Indicadores 2018 RevistaIndicadores2018-final02 - Page 52 GESTION EMPRESARIAL BUSINESS MANAGEMENT Una de las prioridades de todos los hoteles que integran Mayakoba es el bienestar de los colaboradores, realzando valores de educación, respeto, solidadridad, el valor de la familia, un estilo de vida saludable, entre otros. Te invitamos a conocer las buenas prácticas empresariales que realiza cada uno de los hoteles. One of the priorities of all the hotels that make up Mayakoba is the wellbeing of employees, enhancing values of education, respect, solidarity, the value of the family, a healthy lifestyle, among others. We invite you to learn more about the good business practices carried out by each of the hotels. Para Andaz es fundamental la capacitación y el crecimiento de nuestros colaboradores, así como su bienestar, para ello cuenta con diversos programas corporativos. VIDEO ANDAZ MAYAKOBA 52 \| Mayakoba Sustentable 2018 For Andaz, the training and growth of our employees, as well as their well- being, is fundamental, for which it has various corporate programs.Pharmacological and immunological characterization of the Leu5 analogue of human beta-endorphin. The potencies of beta h-endorphin, Met (O)5-beta h-endorphin, and synthetic Leu5-beta h-endorphin have been compared in three bioassays of opioid activity, and in two radioimmunoassays. In all assays, a peptide isolated from hemodialysates from a psychotic patient behaved like Leu5-beta h-endorphin; it has been distinguished unambiguously from beta h-endorphin and Met(O)5-beta h-endorphin. Leu5-beta h-endorphin was one-fifth as potent as beta h-endorphin in guinea pig ileum myenteric plexus, but was only slightly less active in mouse vas deferens and in guinea pig brain opiate receptor binding assay. The low cross-reactivity of Leu5-beta h-endorphin relative to beta h-endorphin with an antiserum raised to beta-endorphin suggests that the preferred solution conformations of these peptides are different. In all bioassays beta h-endorphin was 2- to 3-fold less potent than beta c-endorphin.This invention relates generally to microprocessing, and more particularly to providing methods to improve floating point arithmetic operations. In most processors, it is common to see some type of floating point unit (FPU) or other processing unit that completely implements (or at least has enhanced support for) various floating point square root instructions. Implementations of these instructions are based on popular square root algorithms, including non-restoring SRT (Sweeney Robertson Tocher) algorithms, Newton-Raphson algorithms, Goldschmidt algorithms and others. Errors may occur during execution of these instructions using any of various algorithms, either due to errors in the design (including the algorithm itself) or due to circuit malfunctions such as manufacturing faults or rare environmental disturbances. Functional checking of these types of floating point square root algorithms and their results using formal verification techniques is not currently available, and such checking would only serve to eliminate design flaws, as opposed to malfunctions occurring during execution. Accordingly, other techniques have been devised to try and verify the correctness of the algorithm and/or the result. For example, previous machines have focused on verifying the internal verifiable mathematical operations of the square root using parity and residue checks. While these techniques can verify the correctness of each internal operation, they do not speak to the correctness of the square root algorithm or the final result. Thus, it would be desirable to be able to detect errors in the final result of a floating point square root algorithm, particularly to detect errors occurring due to a circuit malfunction. Such an ability would be useful in providing a method to verify the actual results of a square root operation without the need to verify each mathematical step in the algorithm.Q: Move a sequential set of commits from one (local) branch to another Is there a way to move a sequential set of commits from one (local) branch to another? I have searched quite a bit and still haven't found a clear answer for what I want to do. For example, say I have this: master A---B---C \ feature-1 M---N---O---P---R---Q And I have decided that the last 3 commits would be better off like this: master A---B---C \ feature-1 M---N---O
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Then for every $\eta>0$ with $(1+C)\eta<1$ and for every sequence $(z_i)\subset S_X$ with $d(z_i,Z_i)<\eta$ for all $i\in{\mathbb{N}}$, there is a subsequence $(x_i)$ of $(z_i)$ and a weakly null sequence $(y_i)\subset S_X$ such that $\|\|x_i-y_i\|\|<2(1+C)\eta$ for all $i\in{\mathbb{N}}$. Indeed, we can pass to a weakly Cauchy subsequence $(x_i)$ of $(z_i)$ such that $$\label{P1E1} \|\|P^E_{[1,n]}(x_i-x_j)\|\|< \eta 2^{-j}\quad\forall n\in{\mathbb{N}}\textrm{ and }i>j\geq n.$$ Since $d(x_i,Z_i)<\eta$, we have $\|\|P^E_{[1,i]}x_i\|\|<C\eta$ for all $i\in{\mathbb{N}}$. Since $(E_i)$ is shrinking, the sequence $(P^E_{(i,\infty)}x_i)$ is weakly null, and so for each $n\in{\mathbb{N}}$ there exists $(a_i^{(n)})_{i=n}^{K(n)}=(a_i)_{i=n}^K\subset [0,1]$ such that $\sum_{i=n}^K a_i=1$ and $\|\|\sum_{i=n}^K a_i P^E_{(i,\infty)}x_i\|\|<\eta$. Set $$y_n=\frac{x_n-\sum a_i x_i}{\|\|x_n-\sum a_i x_i\|\|}.$$ We have that $$\begin{aligned} \left\Vert\sum_{i=n}^K a_i x_i\right\Vert\leq\sum_{i=n}^K a_i\|\|P^E_{[1,i]}x_i\|\|+\left\Vert\sum_{i=n}^K a_i P^E_{(i,\infty)}x_i\right\Vert <\sum_{i=n}^K a_i C\eta+\eta =(1+C)\eta\ ,\end{aligned}$$ which implies that $\|\|x_n-y_n\|\|<2(1+C)\eta$. We also have $$\begin{aligned} \|\|P_{[1,n]}y_n\|\|\leq 2\Big\\|P_{[1,n]}(x_n-\sum a_i x_i)\Big\\| \leq2\sum a_i\|\|P_{[1,n]}(x_n-x_i)\|\|<2\eta 2^{-n}\ ,\end{aligned}$$ which tends to zero as $n\rightarrow\infty$. Hence $(y_n)\subset S_X$ is weakly null as $(E_i)$ is shrinking. We now continue with the proof of the implication $(c)\Rightarrow(b)$. Assume that $S$ does not have a winning strategy for the $(A,{\varepsilon})$ game for some ${\varepsilon}>0$. As this game is determined [@Ma] , there exists a winning strategy $\phi$ for the point chooser. The function $\phi$ takes values in $S_X$: if $(k_i),(m_i)\in[{\mathbb{N}}]^\omega$ are the choices by player $S$ and if $z_n=\phi(k_1,m_1,...,k_n,m_n)$ for all $n\in{\mathbb{N}}$, then $d(z_i,Z_{m_i})<{\varepsilon}2^{-i}$ for all $i\in{\mathbb{N}}$ and $(k_i,z_i)\not\in \overline{A_{5C{\varepsilon}}}$. We can, of course, assume that $(1+C){\varepsilon}<1$. For each $\alpha\in T_\infty^{\textrm{even}}$ set $z_\alpha=\phi(\alpha)$. Then $(z_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ is a normalized even tree in $X$ no branch of which is in $\overline{A_{5C{\varepsilon}}}$. Its nodes $(z_i)=(z_{(k_1,\dots,k_{2\ell-1},i)})_{i>k_{2\ell-1}}$ satisfy $d(z_i,Z_i)<{\varepsilon}2^{-\ell}$ for all $i>k_{2\ell-1}$. By repeated applications of our preliminary observation we can find a full subtree $(x_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ of $(z_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ and a weakly null even tree $(y_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ such that $\|\|x_\alpha-y_\alpha\|\|<2(1+C){\varepsilon}2^{-\ell}$ for all $\ell\in{\mathbb{N}}$ and $\alpha=(k_1,\dots,k_{2\ell})\in T_\infty^{\textrm{even}}$. Since no branch of $(x_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ is in $\overline{A_{5C{\varepsilon}}}$, it follows that no branch of $(y_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ is in $\overline{A_{C{\varepsilon}}}$. Thus $(c)$ fails. We will be applying Proposition \[P1\] for the case $A=\{(n_i,x_i)_{i=1}^\infty \,\| (v_{n_i}) \textrm{ dominates } (x_i)\}$ where $(v_i)$ is a 1-unconditional basic sequence. We will also be repeatedly applying the technique of blocking FDDs. For this reason it is important that properties of $\bar{\delta}$-skipped blocks are preserved by blockings. This follows at once from the following simple observation: Assume that $(E_i)$ is an FDD with projection constant $K$, and $(H_i)$ is a blocking of $(E_i)$. Then a $\bar{\delta}$-skipped block of $(H_i)$ is a $2K\bar{\delta}$-skipped block of $(E_i)$. We will be concerned with a space $X$ which satisfies subsequential $V$-upper tree estimates. However the nature of our proofs require us to work with $X^$ as well. This is because some of the blocking techniques which we use depend on the FDD being boundedly complete. Before stating a duality result on upper tree estimates, we need the following definition: A basic sequence $V=(v_i)$ is [$C$-right dominant* ]{}(respectively, $C$-left-dominant) if for all sequences $m_1{\!<\!}m_2{\!<\!}\dots$ and $n_1{\!<\!}n_2{\!<\!}\dots$ of positive integers with $m_i{\!\leq\!}n_i$ for all $i{\!\in\!}{\mathbb{N}}$ we have that $(v_{m_i})$ is $C$-dominated by (respectively, $C$-dominates) $(v_{n_i})$. We say that $(v_i)$ is right-dominant or left-dominant if for some $C{\!\geq\!}1$ it is $C$-right-dominant or $C$-left-dominant, respectively. \[L3\] Let $X$ be a Banach space with separable dual, and let $V=(v_i)$ be a normalized, 1-unconditional, right dominant basis. If $X$ satisfies subsequential $V$-upper tree estimates, then $X^$ satisfies subsequential $V^$-lower $w^$ tree estimates. $X$ has separable dual, so by [@DFJP Corollary 8] there exists a space $Z$ with a shrinking and bimonotone FDD $(F_i)$ for which there is a quotient map $Q:Z\rightarrow X$. After renorming $X$ we may assume that it has the quotient norm $\|\|x\|\|=\inf_{Qy=x}\|\|y\|\|$ for all $x\in X$. This gives that $Q^$ is an isometric embedding of $X^$ into $Z^$. Furthermore, $(F^_i)$ is a boundedly complete FDD for $Z^$ as $(F_i)$ is shrinking. We next show that if $(x_i)\subset S_{X^}$ is $w^$ null, then there is a subsequence $(x'_i)$ of $(x_i)$ and a weakly null sequence $(y_i)\subset S_X$ such that $x'_i(y_i)>\frac34$ for all $i\in{\mathbb{N}}$. We have $(Q^x_i)$ is $w^$ null in $Z^$ as $Q^$ is $w^$ to $w^$ continuous. Hence there is a subsequence $(x'_i)$ of $(x_i)$ such that $\|\|P^{F^}_{[1,i)}Q^x'_i\|\|
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187, 5088, 187, 4140, 577, 11, 82, 428, 3307, 426, 428, 20, 11, 87, 13, 577, 11, 82, 559, 608 ]	a + 5c - 848. Is 42 a factor of a? False Let s(r) = -3r - 5. Suppose 0 = 3z - 9 - 39. Let t = 10 - z. Is 8 a factor of s(t)? False Let z(v) = v*3 + 25v*2 - 117v - 11. Is z(-26) a multiple of 5? True Suppose 12q = -12013 + 31597. Is 16 a factor of q? True Let r(v) be the first derivative of -1/3v*3 - 5v*2 - 4 + 0v. Is 7 a factor of r(-7)? True Let k be (-27)/(-6)16/(-12). Let m = -6 - k. Does 11 divide (-1 - m)/(13/(-286))? True Suppose 0 = 3j + 2i - 11 - 5, -3j = -5i - 23. Let s(y) = -y3 + 10y*2 - 11y - 13. Is 13 a factor of s(j)? True Suppose 4p - 1055 - 1038 = -f, 4f = 4p + 8272. Is f a multiple of 48? False Let f(q) = 8q*2 - 4q - 2. Let r be f(2). Let c be (4/(-5))/(r/(-55)). Suppose 3t + ct + 4x - 212 = 0, 0 = 4t - 3x - 182. Is t a multiple of 13? False Let h(s) = -s3 - 7s*2 + 7s - 7. Let l(c) = c3 + c2 - 2c + 4. Let f be l(-3). Let o be h(f). Is 1/(-2 + o) - -25 a multiple of 12? True Let q = 23 + 14. Let g = 5 + q. Is g a multiple of 14? True Let s = -12 - -15. Let h(k) = 5k*2 - k - 6. Is 6 a factor of h(s)? True Let y = 283 - 104. Suppose b - 90 = 5f, -3b + 449 = 5f + y. Does 22 divide b? False Suppose 3p - 18 = -4j, -2p + 12 = -0p + 5j. Suppose -ph = -h - 240. Suppose z + z = h. Is z a multiple of 12? True Suppose -3n + 6n - 183 = 0. Let k = -42 + n. Is k a multiple of 19? True Let d = 7 - -6. Let g(z) = z*3 - 12z*2 + 14z - 10. Is g(d) a multiple of 46? False Let c(r) = r*3 + 4r*2 + 2r. Let h be c(-3). Suppose 0u + hu - 21 = 0. Suppose -607 + 110 = -um. Is 20 a factor of m? False Suppose 0 = 3u - 3o - 15, -5u - 5o = -2o - 17. Suppose 0 = y - 5m - 1, -5y - 23 = um + 30. Does 9 divide (0 + (-1 - 0))y? True Let s be (1 - 0)/((-5)/(-675)). Does 10 divide 4/(s/66 - 2)? False Let h = 0 + -9. Let m(j) = j*2 + 6j + 18. Does 21 divide m(h)? False Suppose 0 = 2r + 2, -4r - 2 - 4 = x. Let m(y) = -y*3 + 2y + 2. Is 6 a factor of m(x)? True Let l = 7 - 5. Suppose lk = -k + 114. Is k a multiple of 8? False Suppose g - 795 = 1266. Is 21 a factor of g? False Let k(f) = 47f + 5. Let b(u) = 41u. Let r(v) = 42v + 1. Let o(i) = 5b(i) - 6r(i). Let x(a) = -4k(a) - 3o(a). Does 23 divide x(-1)? False Suppose 8 = -3k + 7k. Suppose 5q + k - 27 = 0. Suppose 0 = -qx - 0x + 45. Is x a multiple of 9? True Let f(s) = 16s*2 + 25s + 154. Does 4 divide f(-5)? False Let g be (16/10)/((-4)/10). Let t be g/(-3)(-90)/20. Does 2 divide t/8 - (-253)/44? False Let v(s) = -s + 9. Let q be v(14). Let f = q + 31. Is 13 a factor of f? True Suppose -4y = -2y - 88. Let a = y - -177. Is a a multiple of 11? False Let t(h) = 141h3 - h2 + 4h - 4. Does 14 divide t(1)? True Suppose 14 = 2s + 4q, 4s - 3q - 21 = -4. Suppose si - 20 = 30. Suppose -2b = -0b - i. Is b even? False Let i(t) = -t*2 - 5t - 4. Let k be i(-3). Suppose v = 4a + 22, -ka = -v - a + 13. Suppose -v = x - 3x. Is 4 a factor of x? False Let s = -2546 - -3622. Suppose s + 1304 = 10d. Is 9 a factor of d? False Let v(i) = 2i. Let n be v(1). Suppose 3b = 5b - 8. Suppose -bh + 88 = -2z, 121 = 5h + z + nz. Is h a multiple of 15? False Suppose 5y - 5631 - 2319 = 5u, 0 = 5y - 3u - 7960. Does 55 divide y? True Suppose 2u - 82 = -3x + 43, 186 = 3u + 4x. Suppose -188 = -l - u. Suppose 0 = -2y - 0h - 2h + l, -y = -3h - 69. Does 33 divide y? True Suppose -4p = -0g - g + 16, -4p = 4g - 4. Suppose ga = -a + 10. Suppose 3y + ay - 115 = 0. Is y a multiple of 3? False Let b = 626 - 381. Suppose 112 = 7c - b. Does 51 divide c? True Let r = -122 + 312. Suppose -4o + 122 = -r. Does 26 divide o? True Suppose 22c = 19c + 30. Let r be ((-6)/(-5))/(c/25). Suppose rf - 26 = 2f. Is f a multiple of 13? True Let i = -154 + 364. Is 20 a factor of (i/(-8))/((105/80)/(-7))? True Let t = -64 - -488. Suppose -5u + j = -t, 2j = 2u - u - 83. Is 18 a factor of u? False Suppose 5s + 3k = 818, -2s - 5k = -5s + 484. Does 8 divide s? False Let a(x) = x*2 - 4x - 8. Let k be a(5). Does 38 divide (-1)/(-3)579 + k? True Let l = -39 - -92. Let v(w) = 9w - 2 + lw2 - 11w + 1. Is 18 a factor of v(-1)? True Let i(o) = -15o - 20. Let v(b) = 1. Let p(x) = i(x) + 30v(x). Is 23 a factor of p(-7)? True Suppose -11i + 1315 + 3173 = 0. Is 3 a factor of i? True Suppose 1082 = 4c + 2m, 5c - 544 = 3c - 4m. Let b = c + -162. Does 18 divide b? True Suppose 4q - 22 = -3v, 4*q + 5
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Ten eerste moet ervoor worden gezorgd dat de regelgeving voor de interne markt die al is aangenomen ten uitvoer wordt gelegd. Alle lidstaten moeten de regelgeving voor de interne markt tijdig en op transparante wijze invoeren, en de Commissie heeft tot taak zorgvuldig en consequent toe te zien op de tenuitvoerlegging daarvan. Ten tweede moet de neiging tot protectionisme worden beperkt. Bescherming zal slechts fragmentering van de Europese markt in de hand werken en ons totale concurrentievermogen verminderen. Ten derde moeten diverse transactiekosten die de vlotte werking van de Europese economie in de weg staan worden verminderd. Dit betreft niet alleen mechanismen zoals een doeltreffende, eenvoudige en buitengerechtelijke procedure voor het oplossen van geschillen, maar ook gebruiksvriendelijk grensoverschrijdend e-management met een functionerende elektronische uitwisseling van de benodigde informatie en documenten. De vierde richting is een grotere betrokkenheid van maatschappelijke groeperingen bij de vorming en uitvoering van beleid overeenkomstig de in het Verdrag van Lissabon vervatte beginselen. Tot slot, mijnheer de Voorzitter, wil ik graag alle schaduwrapporteurs en coördinatoren bedanken voor hun bijdrage en de doelmatige samenwerking die daaruit is voortgevloeid, die het ons vandaag hopelijk mogelijk zal maken resoluties over de interne markt met een overtuigende meerderheid aan te nemen, en de werkzaamheden voort te zetten die de laatste jaren zijn uitgevoerd voor de ontwikkeling van wetgeving die de interne markt werkelijk zal consolideren en er een instrument van zal maken om groei en banen in Europa te scheppen. António Fernando Correia De Campos rapporteur. - (PT) Mijnheer de Voorzitter, mijnheer Barnier, dames en heren, het Parlement heeft gereageerd op het verzoek van de Commissie betreffende de maatregelen die nodig zijn voor revitalisering van de interne markt middels het verslag waarover we vandaag debatteren en stemmen. Uit de negentien voorstellen in verband met de Single Market Act voor Europeanen, waarvoor ik rapporteur ben geweest, hebben we vijf prioriteiten vastgesteld volgens de criteria tastbaarheid en haalbaarheid binnen een relatief kort tijdsbestek. Ten eerste moeten we de mobiliteit van de Europese burgers vergroten middels wederzijdse erkenning van beroepskwalificaties, beroepsbewijzen, het Europese vaardighedenpaspoort en de regelmatige meting van mobiliteit binnen de EU. Ten tweede moeten we de grenscontroles op ingevoerde goederen uit derde landen verbeteren en een meerjarenactieplan opstellen voor markttoezicht en productveiligheid. Ten derde moet de termijn van de verordening over roaming worden verlengd tot juni 2015, met prijsplafonds voor roaming om de kosten voor burgers en bedrijven te verminderen. Ten vierde moeten we de toegang tot basisbankdiensten waarborgen en de transparantie en vergelijkbaarheid verbeteren. Ten vijfde moeten de obstakels worden weggenomen waarmee mobiele werknemers worden geconfronteerd, teneinde te zorgen voor de volledige overdraagbaarheid van hun pensioenrechten. Hierover waren we het al snel eens. Lastiger was het overeenstemming te bereiken over maatregelen om wat te doen aan de in het verslag-Monti genoemde moeheid van de Europeanen met betrekking tot de interne markt en om te komen tot de holistische, gezamenlijke benadering als antwoord op de behoeften en het wantrouwen van de burgers, die onmiskenbaar werden vastgesteld in het verslag-Grech dat in mei vorig jaar is goedgekeurd door dit Huis. Wij zijn stellig van mening dat het kunstmatig is het werk van het Parlement te verdelen in drie afzonderlijke verslagen, ondanks de inspanningen van de Commissie interne markt en consumentenbescherming om de analyses en acties te verenigen. Met de drie componenten - ondernemingen, Europeanen en bestuur - zal gelijktijdig vooruitgang moeten worden geboekt willen we kunnen zorgen voor een competitieve interne markt, met slimme, inclusieve en duurzame groei en waarin de Europeanen centraal staan. Wij zijn ons er verder van bewust dat het als gevolg van de proliferatie van initiatieven van de Commissie op dit gebied, samen met Europa 2020, het industriebeleid en het Europa van de innovatie, niet meer goed duidelijk is waar de revitalisering in feite voor is bedoeld, namelijk dat we het idee van een interne markt niet alleen vriendelijker maar ook aantrekkelijker maken voor de Europeanen. Consensus, mijnheer de Voorzitter, dames en heren, was het lastigst te bereiken over twee kwesties. De eerste betreft de eerbiediging van sociale waarden en rechten. Leden ter rechterzijde en van de Fractie Alliantie van Liberalen en Democraten voor Europa aanvaardden slechts schoorvoetend dat het noodzakelijk is de sociale rechten van de Europeanen permanent te waarborgen om hen te behoeden voor de gevolgen van marktoverwegingen in toekomstige wetgeving. We betreuren in het bijzonder dat een verwijzing naar de herziening van de richtlijn betreffende de terbeschikkingstelling van werknemers niet is aanvaard als prioriteit. De tweede kwestie betreft de waarborging van maatschappelijke diensten van algemeen economisch belang. Op dit punt beoogden we te voorkomen dat de activiteiten van die diensten inhoudelijk onderworpen zouden worden aan louter marktoverwegingen of in ieder geval dat het mogelijk zou zijn openbare maatschappelijke diensten om te vormen tot particuliere monopoliën of oligopoliën op zulke gebieden als watervoorziening, stadsvervoer, onderwijs, gezondheid en sociale dienstverlening. Hoewel de invoering van concurrrentiegericht beheer en internemarktmechanismen in die diensten nuttig kan blijken, zullen de sociale waarden die samengaan met universele toegang moeten worden gewaarborgd, aangezien de beginselen van solidariteit in dergelijke gevallen zwaarder wegen dan louter marktoverwegingen. Op dit punt ondervonden we verzet van de fracties ter rechterzijde in dit Huis tegen de aanvaarding van Europese wetgeving over dit onderwerp en het enige waarmee zij instemden was dat de Commissie "alle mogelijke opties moet aanwenden, in overeenstemming met artikel 14 [en] Protocol 26” van het Verdrag. De fractie waartoe ik behoor, heeft zich onthouden van de eindstemming over de drie verslagen in de commissie, aangezien er geen vooruitgang was geboekt met de sociale dimensie van de interne markt. Na de stemming in de commissie zijn er echter wel enkele positieve punten opgenomen waarmee het verslag aanzienlijk is verbeterd. Er is overeenstemming bereikt via een reeks compromissen, waarbij de definitieve amendementen werden onderschreven door de belangrijkste fracties en er geen winnaars of verliezers waren. Alle fracties hebben bijgedragen tot het e
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(McKannay v. Horton, supra, 151 Cal. at p. 720.) Disqualification is a civil disability. (Helena Rubenstein Internat. v. Younger, supra, 71 Cal. App.3d at p. 418.) Accordingly, Carpenter's appeal does not stay his removal from office. D We are aware of the decision in McCormick v. United States, supra, 500 U.S. ___, which may or may not affect Carpenter's judgment on appeal. Carpenter's personal tragedy would certainly be compounded were the 1431 judgment set aside.[7] We emphasize the question of Carpenter's entitlement to office upon reversal is not before us and is not addressed here. DISPOSITION The petition is denied. Work, Acting P.J., and Nares, J., concurred. NOTES [1] Pursuant to California Rules of Court, rule 976.1, this opinion is certified for publication with the exception of part I. [2] The petition was originally filed in the Supreme Court. By order dated April 23, 1991, the Supreme Court transferred the matter here. [3] Matthew Fong is the son of March Fong Eu. Fong, as real party in interest, and the Republican Party, as amicus curiae, oppose the petition on identical grounds. For simplicity, we group the opposition as "respondents." [4] Amended by order on May 9, 1991. [5] All statutory references are to the Government Code unless otherwise specified. [] See footnote 1, ante, page 1422. [7] Such a scenario is not without precedent. Lieutenant Governor of California Ed Reinecke was found guilty of perjury (18 U.S.C. § 1621) by a jury in the United States District Court for the District of Columbia. His conviction was reversed on appeal. (United States v. Reinecke (D.C. Cir.1975) 524 F.2d 435, 440 [173 App.D.C. 274].) Jinze Jinze () is a town in Qingpu District of Shanghai, China. As of the 2017 census it had a population of 60,800 and an area of . The town is bordered by two provinces, namely Zhejiang and Jiangsu. With convenient land and water transportation, it is an important transport hub linking Shanghai, Zhejiang and Jiangsu. It is surrounded by the towns of Shenta, Zhouzhuang and Jinxi on the northwest, Liantang Town on the southeast, Zhujiajiao Town on the east, and the towns of Dingshan and Dashun on the southwest. Name Jinze, formerly known as "Bainingli" (). According to Chorography of Jiangnan (), the name derives from a farmer got a stone of the same colour as gold. History In 978, it used to be in the territory of Northern Song Empire (960–1127) under the jurisdiction of Huating County (). In 1279, the Yuan Empire (1271–1368) set up province system to maintain control of the vast region. Jinze under the jurisdiction of Songjiang Prefecture () of Zhejiang Province. In 1573, in the ruling of Wanli Emperor (1573–1620) of the Ming dynasty (1368–1644), Qingpu County was established. Jinze belonged to Qingpu County. In 1743, in the reign of Qianlong Emperor (1736–1795) of the Qing dynasty (1644–1911), four townships was founded, namely Haizhong Township (), Haishang Township (), Huazhong Township () and Huashang Township (), Jinze came under the jurisdiction of Huashang Township. In 1909, the Qingpu County was divided into 16 autonomous districts, Jinze was one of them. In 1912, after the establishment of the Republic of China, Jinze became a township. In 1929, the whole county was divided into 13 districts, Jinze was the Fifth District. In 1934, after the merger of districts, it belonged to the Fourth District. In February 1948, after the adjustment of administrative divisions, Jinze became a township. In July 1949, Qingpu County was divided into 8 districts, Jinze was one of them. In May 1957, Jinze Township was founded. In September 1958, it was renamed "Jinze People's Commune". In May 1986, it was upgraded to a town. In March 2004, the towns of Shangta () and Xicen () were merged into the town. Administrative division As of 2017, the town is divided into 5 communities and 30 villages: Jinxi Community () Jinyang Community () Xicen Community () Liansheng Community () Shangta Community () Xuli () Xinchi () Jinze () Yangwan () Dongxi () Jianguo () Jinyao () Xingang () Cenbo () Xicen () Santang () Yutian () Hezhu () Aiguo () Dongtian () Rentun () Tianshanzhuang () Gongdu () Qiansheng () Dianhu () Lianhu () Caibang () Dongxing () Wanggang () Shuangxiang () Nanxin () Chendong () Xuemi () Dianxi () Shagang () Geography The Dianshan Lake is located in the town, it is the largest freshwater lake in Shanghai. Jinze is in the subtropical oceanic monsoon climate zone and exhibits four distinct seasons. It has an average annual temperature of , total annual rainfall of , and a frost-free period of 247 days. Economy The local economy is primarily based upon aquaculture and local industry. The main aquatic products are crabs, turtles, eels, shrimps and various freshwater fish. Culture The Farmland and Mountain Folk Song () is a national-level intangible cultural heritage. Tourist attractions According to historical records, there had been "Six temples, a tower, thirteen archways and forty-two bridges" in the town, among which 21 old bridges survived till today. It is the only town that has so many old bridges in Shanghai, thus earning itself the accolade "the top Bridge Town of Jiangnan region". The five bridges spanning parallel over the river course in the vicinity of Xiatang Street in particular, were built respectively in the Song, Yuan, Ming and Qing dynasties (960–1911), so there was a saying "Bridges of four dynasties are stringed by one river". Of the five, Puji Bridge and Wan'an Bridge, built in the Southern Song dynasty (1127–1279), are the oldest stone arch bridges in Shanghai. The two being collectively known as the "Sister Bridges". Religion Yihao Temple () is a Buddhist temple in the town. It was originally built in the Southern Song dynasty (1127–1279) and renovated in the following dynasties, the temple had reached unprecedented heyday in the Yuan dynasty (1721–1368), overtaking Lingyin Temple and Chengtian Temple. Transportation The town is connected to two highways: National Highway G318 and G50 Shanghai–Chongqing Expressway. The main channel is the Taipu River (). Notable people Wang Dajue (), writer. K. K. Chen (), Chinese-American pharmacologist. Jiang Linhua (), sailing competitor. References Bibliography Category:Towns in Shanghai Category:Divisions of Qingpu DistrictEffects of fasting and refeeding on insulin binding to liver plasma membranes and hepatocytes from normal rats. The effect of acute and chronic starvation on insulin binding to liver cells and liver cell membranes was studied in normal rats. A short-term (1 day) fasting period did not induce significant changes in insulin binding to liver plasma membranes in spite of the hypoinsulinemia present in the rats, as compared with normo-insulinemic fed controls. Longer periods of fasting (2 and 4 days) elicited an increase in insulin binding to liver membranes that was due to an increase in the number of insulin receptors rather than to changes in affinity. All groups of membranes were similar with respect to the rates of association and dissociation of hormone, degree of negative cooperativity and extents of both hormone and receptor inactivation. The fasting-induced increase of insulin binding was not a consequence of the methodological procedure for membrane isolation since the same conclusions were obtained when intact hepatocytes were used. Refeeding of fasted animals resulted in a decrease of insulin binding together with an increase of insulinemia towards the fed control values. These results suggest that the number of insulin receptors is inversely related to the circulating levels of the hormone and support the hypothesis of insulin regulating its own receptor.MERS-CoV, South Korea, Cases (7 June 2015) As of early this morning (presumably including cases up to Sunday 7th June), there are now 87 cases of MERS-CoV infection in South Korea, with 6 deaths. The updated list of cases is at the Flutrackers forum here. There is also a list of 24 hospitals that is managing or had been visited by patients with MERS, although some inaccuracies have been noted in the list. There appears to be at least one other “super-spreader”, a 40-year-old man who had been on the same ward as the
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27372, 4407, 1389, 13709, 4189, 7620, 2964, 1152, 38077, 27123, 13, 187, 4183, 23346, 3504, 6205, 26072, 26610, 10324, 7065, 1207, 6099, 8961, 5126, 21475, 15095 ]	� kết nối. Chắc hẳn bạn biết rõ tính huống khi mà bạn nhận được đánh giá từ bà chủ của mình, và bà ấy chỉ cho bạn 37 thứ bạn làm thực sự tốt, và một thứ -- một cơ hội để làm tốt hơn? (Cười lớn) iw: כי אני מתעניינת בכמה נושאים מאד מבולגנים. אך יש לי רצון להצליח להפוך אותם ללא מבולגנים. אני רוצה להבין אותם. אני רוצה להצליח לפרוץ אל אותם דברים שברור לי שהם חשובים ולהציג את החוקיות שלהם לעיני כל. והמקום שהתחלתי ממנו היה הקשר. שכן, בנקודה שבה אתם עוסקים בעבודה סוציאלית כ-10 שנים, מה שאתם מבינים הוא שקשר הוא הסיבה שבגללה אנו כאן. הוא מה שמעניק מטרה ומשמעות לחיינו. זהו הדבר המהותי ביותר. זה לא משנה אם אתם מדברים עם אנשים שעובדים כפעילים חברתיים או בבריאות הנפש או בנושאי התעללות והזנחה, מה שאנו יודעים הוא שקשר, היכולת להרגיש קשור, היא -- נוירוביולוגית, זה האופן בו אנו מחווטים -- זו הסיבה שבגללה אנו כאן. ואני חשבתי - יודעים מה, אני אתחיל עם קשרים. אם כן, אתם מכירים את המצב הזה שאתם מקבלים הערכה מהמעבידה שלכם, והיא אומרת 37 דברים שבהם אתם ממש מדהימים, ודבר אחד שהוא - "הזדמנות לצמיחה". (צחוק) Lithuanian: nes mane domina nešvarūs dalykai. Tačiau noriu sugebėti juos sutvarkyti. Aš noriu juos suprasti. Noriu įsilaužti į tuos dalykus, kurie yra svarbūs ir pateikti kodą matomą visiems. Taigi, aš pradėjau nuo ryšio. Nes, kai jau 10 metų esi socialinis darbuotojas, suvoki tai, kad būtent ryšio dėka mes visi esame čia. Tai suteikia tikslą ir prasmę mūsų gyvenimams. Štai kas tai yra. Ir visai nesvarbu, ar tu kalbi su žmonėmis, kurie dirba socialinio teisingumo, ar psichinės sveikatos srityje, su patyrusiais prievartą, su apleistais – mes žinome, kad tas ryšys, tas gebėjimas jaustis susijusiam, yra todėl, kad mes taip sustyguoti neurobiologiškai - ir dėl to esame čia. Taigi pamaniau, žinote ką - pradėsiu nuo ryšio. Ko gero, žinote tokią situaciją, kai viršininkė vertina jūsų darbą ir susako 37 dalykus, kuriuos darote tiesiog baisiai ir vieną dalyką - kaip galimybę augti? (Juokiasi) Norwegian: fordi eg er interessert i kinkige tema. Men eg har lyst å vere i stand til å gjere dei ikkje-kinkige. Eg ønskjer å forstå dei. Eg vil hakke laus på desse tinga eg veit er viktige og løyse koden slik at alle andre ser det. Så eg starta med tilknyting. Fordi når du har vore sosionom i ti år skjønar du at tilknyting er grunnen til at me er her. Det er det som gir liva våre mål og meining. Det er det alt handlar om. Det betyr ikkje noko om du snakkar med menneske som jobbar med sosial rettferd, mental helse og misbruk og forsøming, det me veit er at tilknyting, evna til å føle tilknyting er -- den nevrobiologiske måten me er skrudd saman på -- det er grunnen til at me er her. Så eg tenkte: veit du kva, eg startar med tilknyting. Og du kjenner situasjonen kor du blir evaluert av sjefen din, og ho fortel deg 37 ting du gjer på ein framifrå måte og ein ting -- ein "muligheit for vekst?" (Latter) Bulgarian: защото се интересувам от объркани теми. Но искам да мога да ги подредя. Искам да ги разбера. Искам да проникна в тези неща, за които знам, че са важни и да ги направя разбираеми за всички. Това, с което започнах, беше връзката. Когато имаш около 10 години стаж като социален работник разбираш, че връзката е това, заради което сме тук. Тя дава причина и значение в нашият живот. Това е всичко. Няма значение дали говорите за хора, които работят по теми като социална справедливост, ментално здраве, малтретиране и пренебрегване, това, което знаем е, че връзката, способността да се чувстваме свързани, невробиологично е начинът, по който ние се обединяваме - затова сме тук. Помислих си, че ще започна с връзка. Позната ви е ситуацията, в която получавате оценка от
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Our vehicle ecellerates to 88 MPH in 2 seconds, as we must go Back to the Studio! We arrive back to the studio as the artists appear overhead on screens congratulating us for surviving and that we can come back any time! We then exit our vehicles and head out back to Production Central. The Vagabond Adventure Tours is the leading touring company in the world offering tours that are fun, exciting and yes even a little educational! But they are not your typical adventure company offering Safari trips in Africa or white water rafting on the Amazon, they offer Disaster Tours! The Vagabond Adventure Tours offers disaster tours all over the world getting there adventurers closer to the event than any other disaster touring country could. They have had tours to New Orleans right after Hurricane Katrina hit, brought adventurers to the 2010 eruption of Eyjafjallajökull volcano in Iceland, and still offers adventurers a chance to get closer to the biggest nuclear power plant disaster at Chernobyl. There newest offering to adventurers is a chance to see and experience an ongoing flooding of a whole American town. Willimantic is a large town located in California that just experienced an earthquake that partially damaged a dam uphill from them. The earthquake also damaged the Kravet Nuclear Power Plant near to them but The Nuclear Regulatory Commission (NRC) has stated that has stated that the damage to the power plant was minimal and radiation leaks have been contained. The 90% of the inhabitants of Willimantic are feared dead due to the sudden break of the dam and the flooding it caused. The Vagabond Adventure Tours has bought an abandoned sporting goods store and made that the meeting place for their new tour. The Vagabond boat tour will get up close and personal experience of how destructive Mother Nature can be. This boat tour will go from leisurely, to thrilling, to chilling, to downright terrifying! Queue/Building: The area around the ride will look like an abandoned American town with store fronts and houses. The queue and the ride entrance will be a sporting’s good shop that has been abandoned but still intake and next to water. Inside the shop it will look like people who were in there at the time of the earthquake and the flooding just dropped everything and left. The T.V.’s have been left on also to MSNBC and The Weather Channel and other Universal news organizations covering this whole event and then describing to people that there are tours going to the town. Ride: The ride starts in the middle of Main Street Willimantic and the ride starts at a leisurely pace through some of the most prominent areas of Willimantic including government buildings and the town square. The boats also have speakers in them with Alex as the host of the tour explaining details of the town and giving you tips on what to expect. Then the tour takes it first drastic tour. The first tremor hits the town. The tremor is actually more severe than the initial earthquake that hit the town. You hear Alex scream because the dam breaks and your leisurely tour take a wilder ride! Because the dam is uphill to the town the water now comes streaming down the hill and towards you. The boat bucks and twists the boat is straight and then backwards. The boat takes a wild plunge down some steep and long hills. There will be 3 main drops the first is a 30ft drop, the second will also be a 30ft drop but backwards and the last drop is a 55ft drop reaching speeds of 42mph! After the second drop where you go backwards you see the first signs of life. You see in the distance a family of 4, 2 adults and 2 kids. Then after the third and final drop you see more and they are starting to get close. Alex mentions that the other tour boats are seeing more and more but the only thing they can see clearly is a green glow emanating from their eyes. Alex is coordinating effort with other tour guides from The Vagabond Adventure Tours to see if they can get them all together and get them out of Willimantic. She starts asking each where they are and when she asks for Jason he doesn’t answer and they presume he’s busy. Well they are right he is busy! The boat then turns a corner and they see 4 people huddled close together with someone lying on the ground Alex believes it is someone that is hurt and they should stop to assist. When they stop the people turn to the boat their green eyes glowing brighter, you see the skin hanging off their faces, blotchy blood corpse like people. In the middle of the group lying on the ground is a body with a shirt just like The Vagabond Adventure Tours guides wear and he is being torn and eaten by these people! They look up again and start moaning lifting their arms and hands towards you and then get up and start walking towards the docked boat. Yes this is also a Zombie ride! Apparently the nuclear reactor leak was not as minimal as first thought and the people that were feared “missing and dead” were not actually “missing” but here all along. Alex screams and throws the throttle of the boat into full and gets away from this group. All along the edge of the “river” or “street” there are Zombies chasing or walking towards the boat. You can hear the moans all over the place and all over the boat. Alex thinks that if they go down a certain way they can find a way out. Alex sends the boat down another path in which the buildings get closer and closer to the boat. Alex thinks that because the buildings are close the Zombies can’t get to them. Well Alex doesn’t take into the account that the Zombies are in the buildings! They start breaking through windows and reaching out to the boats. One even comes close to dropping into the boat! Well finally Alex gets away from the buildings and says if they can get into the Hassler Tunnel, a tunnel system that connects to State Route 20. The boat finally gets into the tunnel and its dark but you can’t hear any moans so there’s got to be no one in there right? You first see green eyes down in the distance in the tunnel, then in the back of the boat, then on the sides, and then you start seeing instead of one pair of eyes you start seeing dozens of them all around the boat and they are getting closer. Then you hear the moans again echoing all over the tunnel. Fortunately the lights are out and you can’t see them, well that change’s. The fluorescent flood lights start to flicker and each flicker you see them. You see them snarling, walking towards the boats, you see some of them falling into the water and standing and still coming towards you. And each blinding flash you only see them for a split second and each one is more terrifying then the next. At one point during one of the flashes a camera takes a picture of you. Alex decides that they have had enough with safety and guns the engines to the boat as hard as they can to get out of the deathtrap of Hassler’s Tunnel to get back to the sporting goods base. Exit/Base: You finally get back to Base and realize it changed a bit instead of the sporting goods store you saw before well the building hasn’t changed but the inside has. The army and CDC are here and inspecting everyone that has come of the boat making sure nobody is infected! Here are also video screens showing the pictures that were taken during Hassler’s Tunnel. Is it over? After seeing the photos and possibly buying them everyone is ushered into a final hallway to exit in the hallway they are ordered to wait for another boat to come and that person leaves. The hallway is white with other corridors and doors the end of each. On one side of the wall is a mirror. While waiting you hear a roar, then the floor shakes and the lights go out! You were hit with a second tremor. Like before you see the green glowing eyes, hear the moans, and they are all around down each corridor and the door in front and behind you are locked! You hear over the loud speakers that they are working to get you out and just wait and that they are working on the lights. They again flicker and you actually see them getting closer to you, the mirror turns out to be a two way mirror and Zombies are seen and heard banging on the glass. Finally the lights go fully out and the glowing eyes move back and finally fad away with the lights finally turning on for good. The doors open to the exit and as guests leave the hallway they are immediately met with a large tank sitting in front of the door with the barrel of the tank pointing directly at the door! Technical Stuff: The ride will be a Flume ride using the same boats as the Jurassic Park: The Ride at IOA and will be a good complement to it. The boats and the track will be adapted to go backwards as well as forward. The ride will both feature audio animatronics and live performers. There will be more live performers during Halloween in which Hassler’s Tunnel and the Exit Hallway scenes will be even more terrifying! I didn’t include pictures of the Zombies to get the website family friendly and also we all know they look like! Also what make my Zombies unique are the green glowing eyes which gets people to assume that the nuclear power plant is the cause. And yes I do realize that Universal and IOA will have flume rides but WDW has two also and are both very popular.
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32074, 3346, 2506, 626, 2647, 3346, 49745, 21, 15, 20, 9840, 18, 1335, 4453, 5322, 3346, 1014, 1293, 436, 499, 84, 785, 14, 14778, 187, 29, 87, 11282, 520, 31, 285, 352, 2119, 1057, 417, 1007, 751, 627, 588, 320, 247, 2900, 28537, 3517, 347, 275, 436, 1770, 187, 29, 43292, 301, 31, 309, 8038, 259, 280, 69, 323, 23245, 15, 187, 29, 12753, 3245, 83, 46963, 31, 380, 2990, 7205, 275, 49745, 2987, 1270, 352, 434, 253, 1652, 275, 14, 483, 4216, 326, 2506, 626, 789, 275, 577, 15, 20, 9840, 15, 187, 29, 87, 11282, 520, 31, 391, 656, 73, 27, 34746, 2188, 49745, 577, 15, 20, 2391, 849, 7505, 4233, 452, 368, 1119, 352, 281, 320, 32, 187, 29, 610, 1200, 31, 6089, 806, 352, 277, 5168, 417, 1663, 3334, 25863, 3346, 1142, 6332, 326, 352, 3078, 281, 50029, 4367, 432, 643, 12149, 187, 29, 610, 1200, 31, 594, 891, 908, 247, 2257, 273, 277, 19910, 1969, 4774, 50029, 1227, 2044, 16, 25887, 16, 16321 ]	akhia> can you type: file Urb* <alakhia> that should tell you what kind of file you have <Guest31841> ioUrbanTerror.i386: ELF 32-bit LSB executable, Intel 80386, version 1 (SYSV), dynamically linked (uses shared libs), for GNU/Linux 2.2.0, not stripped <alakhia> great ... it is an application <alakhia> so, now type: ./Urban* <Guest31841> still denied <alakhia> what is the exact message? <Guest31841> bash: ./ioUrbanTerror.i386: Permission denied <little> Barridus: Aare you still there? <alakhia> is your userid nick? <Guest31841> yep <alakhia> indulge me and run: chmod a+x Urban* <Guest31841> same thing. denied <alakhia> er, i mean: chmod a+x ioUrban* <tron2000> anyone on here using bitchx as their client <Guest31841> yep did that <alakhia> that is strange ... i'm not sure why you can't access a file that you own <Guest31841> same here.... I can access any other files on the drive. Just cant run that i386 <alakhia> hmmm, is it possible that you mounted the drive using noexec flag? <Guest31841> hmmm <Guest31841> will check <alakhia> do: grep noexec /proc/mounts <Barridus> is it possible to reset permissions? (those popup password prompts that i previously told to remember the permission forever) <alakhia> Barridus: which popup was this? <Guest31841> it does have the noexec flag. weird... shouldnt use mountmanager prog :/ <Barridus> alakhia you know, the prompts for passwords when you make a system change <Barridus> there's radio buttons that say "remember this permission foreveR" or something. i want to reset/clear that <little> barridus: If you open kwallet by typing kwalletmanager in a terminal window, then you can go into the configuration menu and change the settings. <alakhia> ok, mystery solved ... if you copy that file somewhere else, chmod it, then it will work <alakhia> or just remount with noexec off <Guest31841> thanks alakhia. super help <Guest31841> works <alakhia> cool <pondus_> hej <Barridus> little, i'm not sure if that's what i'm looking to do <Barridus> i could have sworn i used to get popups for passwords when adding removing packages in kpackagekit, etc <Barridus> i don't see anything in kwalletmanager for that <alakhia> Barridus: try looking at: ~/.kde/share/config/kwalletrc <alakhia> in case you are brave enough to modify it directly and remove things from "Auto Allow" section <little> Usually if a program asks if you'd like it to remember a password, it kicks in the kwallet automatically. Have you tried going into kpackagekit and having it remember a password? <Barridus> alakhia, hmmm i assume i want to remove things from [Auto Allow] <Barridus> little, yes i believe i did that. want to remove it :) <alakhia> Barridus: be careful .. and make a backup in case things go bad <Barridus> yeah, always ;) <alakhia> also i'm not sure how you can tell kwallet to read the new file ... you might need to log out and back in perhaps? <Barridus> probably <little> Barridus: Ah, that should be possible under the configuration menu, isn't it? <Barridus> i don't see anything in kwalletmanager for kpackagekit specifically <little> Barridus: Did you look in the Access Control tab and expand the listing? <Barridus> mostly just networking related things (KRDC, Kopete, Network Manager, twitter, etc) <Barridus> tab? <Barridus> tab in what, little? i see none in kwalletmanager <little> Barridus: In my kwalletmanager if I go into the Settings menu and then choose Configure Kwallet, there is an Access Control tab with a listing of the programs that use Kwallet. <Barridus> ahhh, ok <Barridus> KDE Control Module? <little> Barridus: That I'm not sure of. In that tab I have kdewallet with a plus next to it. If I click the plus, I get a listing of the programs that use the wallet. Is that where KDE Control Module is? <Barridus> KDE Daemon perhaps? <Barridus> yes <little> Barridus: Someone in the #ubuntu-devel channel might know. <Barridus> hmmm <little> Barridus: I suppose it wouldn't do any harm to remove any entry in the wallet, because it would simply prompt you to add it again if anything needs a password and hasn't got it. (: <Barridus> yeah i suppose <Barridus> heh * little likes to occasionally get yelled at by her computer. (: <Barridus> hmm, no effect. lemme log out and back in <little> Barridus: Okay, crossing fingers. <little> Barridus: How is it going? <pawel> hey guys i managed to run skype under pulseaudio in kubuntu but i have huge trouble with another application that isnt PA compatible. do u know any solution that might help? is there a alsa wrapper that would "fool" the app? <little> No idea, sorry! <rysh> Hi, anybody using kde4.3-beta1 on jaunty?? <rysh> Seems the plasma-widget "system Monitor - network settings" can not find any network interface ... <rysh> anyone who also found this ? ... and maybe have a solution? <vadi01> hi guys. i need to ask how the new kubuntu 9.0.3 is with kde? i ask cause the previos release honestly was terrible <vadi01> and i had to shift my os <vadi01> is rock solid? <vadi01> cause am thinking of downloading and installing it <Num83rGuy> I have the same problem with the net mon. <Num83rGuy> It'll get fixed. <vadi01> Num83rGuy: you refering to my question? <Pondus2> hi...dos anyone know about xbins <vadi01> net mon is buggy from kde itself <Num83rGuy> Nah, it was rysh I was refering to. :) <perseid> Problems with the net mon? As in network access going away randomly? <rysh> Num83rGuy: aha, thanks for replying ... so it seems i am not the only one with this problem <vadi01> Num83rGuy: ok. anyway it seems that kubuntu developers also have a prob with net mon <vadi01> Num83rGuy: is gnomenetwork monitor recommended to be used meanwhile? <vadi01> rysh: what happens? <Num83rGuy> No it doesn't go away randomly just the net mon plasmoid can't find the net interface to monitor. <rysh> I know kde4.3 is BETA and for me it is not a real problem ... just wanted to know if there was a solution available ... <rysh> i am using kde 4.3 beta1 .... and the plasma widget "System Monitor - Network Settings" is not seeing any interface <vadi01> well in fedora-kde its the same prob. <Num83rGuy> Yup thats life in beta. <vadi01> so the developers are using gnome network monitor instead. is this possible in kubuntu? <rysh> Num83rGuy: :-) ... doesn't matter ... kde4.3 beta1 still looks nice ... even without this plsma-widget <vadi01> and it sure does not look like there will be a solution anytime soon as in this month <perseid> I installed wicd for networking. <Num83rGuy> The network manager in kde works great it's the little in-out graph that doesn't work in 4.3 beta. <vadi01> rysh: hmmmm kde 4.3.... how buggy have you found it to be? <rysh> Well first it ddi not really install smoothly ... many errors that it wanted to overwrite files from other packages <rysh> so i used a lot of dpkg --force overwrite /var/xxx/xxxx
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187, 187, 4387, 966, 308, 6361, 6717, 35892, 5089, 551, 535, 50274, 33, 5089, 187, 50274, 4387, 2991, 1071, 5804, 1785, 28704, 7834, 4431, 1082, 551, 50274, 187, 50270, 4531, 29, 46167, 48810, 31, 581, 48810, 426, 47304, 15, 4093, 10747, 9, 1826, 308, 6361, 48810 ]	When he was invited to return to Albert's legacy for the Namatjira Project, "at first I was like, no, I can't do this any more. I just gave up doing Namatjira, in the end, because of the realisation of what the government's not been doing for us, and I just wish there was a resolution. There's still that question to this day, how can we resolve it? How can we resolve the whole Namatjira legacy?" Namatjira Project doesn't answer the question, but neither does it end on a tragic note. While the mission to win back copyright continues, the film makes apparent another aspect of Albert's legacy that lives on: his family have continued to paint in his distinct style, and a new generation of young artists is picking up brushes now. "His DNA keeps on through the younger generations," says Jamieson, "and new generations are what matter." Namatjira Project premieres August 5 at the Melbourne International Film Festival. miff.com.auPages Monday, May 17, 2010 What A WOW Monday! I usually don't care for Mondays. Mondays are late start days for my teenage son and it just messes up my whole morning schedule. But today is a WOW Monday! When I first came across Words of Wisdom I was so excited to see what Sandy and Pam were bringing to the blog world. There are a lot of great blogs out there that need to be seen and that is exactly what Pam and Sandy are doing...exposing wonderful blogs (so I feel incredibly privileged that I was chosen on this Monday and my feelings of Mondays will forever be changed) :) I want to reach out to the world on being positive and share with them how being positive has helped me. I am not perfect and I am not "always" positive but I can say that positivity has brought me where I am today. I have had a roller coaster life since I can remember and I have memories going way back to when I was 3! So I can honestly say I know God has blessed me with positivity to help me survive and make it through this temporary life. I have recently rediscovered my passion for art and writing. I lost that for a while because I forgot who I am. I am still getting used to drawing again and am a slowly getting back into it. My biggest goal in this is to reach out to children and parents so that children can know early on how important it is to be positive. Thank you for visiting my page today from WOW and I hope you will enjoy what I have to say and by all means, if you can contribute, please do! Happy Monday! Please visit Pam and Sandy and read about all the wonderful blogs they have already exposed here at Words of WisdomThis invention relates to an adjustable fluid flow regulator, and in particular to an adjustable fluid flow regulator having a finite adjustment limit. Commercial and Residential gas appliances typically use natural gas or L. P. gas, which are delivered at different pressures. It is desirable to have equipment that can be converted for use with either type of gas, rather than equipment limited in use to just one type of gas. A number of attempts have been made to make an adjustable pressure regulator that is capable of operating within the pressure ranges typical for the two types of gas. Examples of these include Bauman, U.S. Pat. No. 3,747,629; Love, U.S. Pat. No. 4,718,448; Buezis, U.S. Pat. No. 5,435,343; Dalton, U.S. Pat. No. 6,173,775. Most of these devices employ a diaphragm for controlling a valve, a spring for biasing the diaphragm, and a means for varying the spring pressure to adjust the fluid flow regulator. While the prior adjustable fluid flow regulators are useful for the purposes described, there is still a need to reduce the risk of inadvertent adjustment above the pressure ranges typical for natural gas and L. P. gas, or the specified maximum pressures of the appliance manufacturer. The present invention relates to an adjustable fluid flow regulator construction that can be converted between two modes of operation, but which restricts accidental or inadvertent adjustment above a predetermined maximum limit. The regulator of the present invention comprises a casing having an inlet and an outlet, a diaphragm-operated valve, and a servo-regulator diaphragm. The servo-regulator diaphragm regulates the passage of a control gas pressure that is applied to one side of the diaphragm that operates the valve. The valve opens and closes as the diaphragm moves in response to pressure changes on either side of the diaphragm. By adjusting the servo-regulator diaphragm, the control gas pressure can be adjusted to control the opening of the valve. The adjustable fluid flow regulator further comprises a spring for applying pressure against the servo-regulator diaphragm to control the operation of the valve. A first screw and a second screw are both used to adjustably bias the spring against the servo-regulator diaphragm. The second screw, which engages the spring, is adjustably disposed within the first screw. Initially adjusting the regulator involves fully adjusting the first screw to a limit within the regulator, and subsequently adjusting the second screw until the predetermined maximum regulator setting is obtained. Once the maximum setting adjustment is made, the second screw may be restricted from further adjustment in the field by using a non-standard screw head not adjustable by the public, or by a means of covering the screw. Subsequent adjustment would be limited to the first screw and would not exceed the maximum regulator setting established by the limit.Review: EVGA GeForce GTX 670 FTW Power Consumption, Temperature and Noise We found the EVGA card to be slightly more hungry when playing Batman: Arkham City, but there's not a lot in it - the power characteristics of both factory-overclocked cards are similar. Here's where things get interesting. EVGA's GTX 670 FTW does well to keep the factory-overclocked card running below 80ºC under load - it's actually cooler than the stock-clocked reference design - but ASUS's custom-cooled GTX 670 DirectCU II TOP is in a different league all together. We see a similar pattern in our noise evaluation; the EVGA card isn't particularly loud and performs similarly to a reference GTX 680, but it isn't as quiet as ASUS's custom DirectCU II cooler.Although numerous genetic alterations have been causally linked to cancer development, many of the affected genes appear to fall into common cellular pathways. With the advent of technologies capable of assessing the expression of thousands of genes simultaneously, the potential now exists to "reverse- engineer" cancer-related signaling pathways by computer modeling. Towards this end, the objective of this proposal is to develop experimental methods and analysis tools to elucidate the components of signaling networks functionally altered during tumorigenesis. To achieve this goal, prototype pathway modeling algorithms will be tested in Phase I for their ability to detect known relationships among genes manipulated in experimental systems. Specifically, recombinant wildtype versions of genes frequently mutated in cancer development will be inducibly expressed in cell lines, and the resulting expression changes in endogenous genes will be monitored by hybridization to oligonucleotide arrays. Analogous studies will also be performed using cells in which individual genes have been deleted. The protein products of genes that demonstrate altered expression in such studies serve as candidate functional mediators of the ectopically expressed genes. The commercial goal of these studies is to develop broadly applicable tools to facilitate the rational identification of novel diagnostic markers, prognostic markers, and therapeutic targets. PROPOSED COMMERCIAL APPLICATION: We will develop experimental and analytical tools to reverse-engineer signal transduction networks from gene expression profiles. These tools will facilitate the rational identification of novel diagnostic markers and therapeutic targets. As such, they will enhance the sale of high-throughput expression analysis systems and pathway analysis software./* * Copyright 2017 The Apache Software Foundation. * * Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. */ package org.apache.storm.kafka.spout.subscription; import static org.mockito.Mockito.clearInvocations; import static org.mockito.Mockito.inOrder; import static org.mockito.Mockito.mock; import static org.mockito.Mockito.when; import java.util.Collections; import java.util.HashSet; import java.util.Set; import org.apache.kafka.clients.consumer.ConsumerRebalanceListener; import org.apache.kafka.clients.consumer.KafkaConsumer; import org.apache.kafka.common.TopicPartition; import org.apache.storm.kafka.spout.config.builder.SingleTopicKafkaSpoutConfiguration; import org.junit.Test; import org.mockito.InOrder; public class TopicAssignerTest { @Test public void testCanReassignPartitions() { Set<TopicPartition> onePartition = Collections.singleton(new TopicPartition
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352, 369, 26373, 8977, 326, 7911, 5103, 598, 15, 1292, 672, 32509, 1720, 262, 46308, 13, 2488, 273, 795, 510, 31015, 273, 308, 4740, 8291, 11580, 1503, 3399, 15767, 434, 19902, 327, 253, 43744, 10092, 4033, 66, 275, 33287, 13, 253, 4559, 48148, 27510, 2987, 497, 1335, 16453, 314, 33449, 15 ]	: literature, the arts, sciences, philosophy, and the ongoing debate about the future of Marxism. It is fascinating to observe the extent to which she, who never knew her father, chose someone whose inner qualities uncannily resembled his. True, Modigliani, although a Socialist and supporter of Emanuele's causes, was never politically active. But he and Valdi had the same omnivorous intellectual curiosity, the same love for poetry, the same impulsive ability to jump into the middle of a losing fight, and the same gift for keeping up a false front. Speaking of his Resistance years Valdi wrote, "We were like actors wearing masks," performing a life-or-death drama in broad daylight before a public that did not know and would not have cared. Modigliani could have said the same. Valdi was also married to Hélène and had two young sons, Maxime and Alain. In wartime nothing like that stood in the way of people who were deeply in love. Desanti said that the relationship for Jeanne was "determinant, crucial." As for Valdi, he wrote, "Her rebellion was full of verve. The exuberance of her intelligence, her vivacity, her frankness and her charm bowled me over. I was seduced. Our union, begun in a moment of common danger, lasted for thirty years." That a life of high adventure is not only exhilarating but can bring out the very best in people is a truism that applied to Jeanne Modigliani in particular during the German occupation of France. François Vitrani, who became one of Valdi's pupils, called her a "grande Résistante," i.e., a model of courage and "unbelievable audacity." She and Valdi shared, not only the constant fear of being captured and tortured, but missions calling for resourcefulness and the ability to improvise. But the organization Vernant put together had mastered the art of creating forged papers that were persuasive enough to rescue Valdi several times. Similar documents were also used to free Jeanne from prison. She was arrested in October 1943 and released in January 1944. Glodek said, "During the liberation of Paris she was in the middle of things and always fearless." He recalled one day when they—meaning himself, Valdi, and Jeanne—had a rendez-vous on the Left Bank that required them to walk in front of a heavy German field battery, installed behind fortifications on the Place Saint-Michel. At the least sign of fear or haste the suspicious Germans might have opened fire. But Jeanne was magnificent. "She looked the Germans straight in the eye and calmly crossed the square, just like that," he said. Jeanne's defiance sometimes bordered on recklessness. Jean-Pierre Haillus tells the story about one time, during the German occupation, when she and Valdi happened to enter a restaurant full of members of the Gestapo. Jeanne took in the scene, then ordered from the menu. In a loud voice, she would have some "Résistance soup," or words to that effect. Valdi kicked her hard under the table and hustled her out of there. _Les Tribulations d'un idéologue,_ written in 1984 under his alias of Victor Leduc and recently reprinted, is a fascinating account of this French intellectual's Communist beliefs and his slow disenchantment as the truth about Stalin's repressive regime became clear. It was written partly to explain to a new generation how someone like himself, so hard to deceive, could have taken up the cause at great personal risk and continued to believe in its tenets until post-Stalinist revelations made such a belief impossible. At the same time it is a kind of admission that life spent in a clandestine world exacts a high personal price. Being with Jeanne on cloak-and-dagger missions during the war was one thing. Setting up life with Jeanne in a Paris apartment was something else. By 1946 Jeanne had divorced Mario Levi but Valdi had gone back to live with his wife. In his memoir he told the story haltingly, with the kind of understatement one would expect. "After the Liberation my family moved to Paris with me. I had not broken my liaison with Jeanne. I suffered very much in this situation because I was very attached to Hélène, I loved my sons... and we were about to have a baby girl to whom I had given my mother's name of Olga. But I love Jeanne, by whom I also had a daughter, Anne." What Valdi did not mention was that both babies were born in the same month, May of 1946. Maxime Nechtschein said that during the war he seldom saw his father and when he did Valdi was always on the run. He was often obliged to lie for him, something he did not like at all. His father never talked about Jeanne, politics, his work in the Resistance, or anything personal. He was "not much of a talker." However, "he was a very good organizer, very passionate, indefatigable but not practical at all. He had a double life. It was 'la culte du secret.' " G. E. Modigliani in America, 1935 (image credit 14.5) Finally, Valdi moved in with Jeanne. Even then he never talked about her, his son said, and Maxime only met her once or twice. Valdi spent his weekends with Hélène and the children, as if he had been away on some secret mission and returned for a brief holiday. That their father had two other children was something Maxime and his brother did not learn for many years. One of the reasons for Valdi's decision to move in with Jeanne had to do with the state of Anne's health. When she was only sixteen months old she had a cerebral hemorrhage that left her partially paralyzed, with brain damage. Years of therapy and operations would follow before she was able to lead a normal life. All this was happening in 1947, which would have been a terrible year for Jeanne for another reason: her uncle Emanuele had died. After leaving Switzerland at the end of the war, he and Vera returned to Italy in triumph. But his health was fragile and he died there in October 1947, a few days before his seventy-sixth birthday. No doubt Jeanne felt overwhelmed; in any event, this was when Valdi moved in. Ten years later Valdi divorced Hélène and married Jeanne. By then they had a second daughter, Laure, born in 1951. Their father belatedly acknowledged his two illegitimate daughters a year or so before his death in 1993. That would have been in character. Dominique Desanti said, "It is true that the two of them lived only for politics. Militants of that epoch essentially abandoned their children. The best thing was if there was a grandmother on the scene... It was a Bohemian household; they all were. If you wanted to eat, well, you went to a restaurant. Otherwise it was ham and frites or you bought something at a delicatessen. I don't know if Jeanne ever cooked but I'd be astonished if she did. Of course they were very poor. Communist journalists were very poorly paid, considered working class." A rare photograph of Valdi and Jeanne together, postwar, in the countryside with cat (image credit 14.6) Jean-Pierre Haillus agreed. He recalled one time when he was living in Guadeloupe and Valdi arrived there for a conference. They met at the airport. Valdi was in complete sartorial disarray. Everything was unbuttoned and his sole covering above the waist was an undershirt. "A completely Bohemian lifestyle. Jeanne was capable of leaving the house wearing one red shoe and one blue one. It didn't bother her at all. Possessions didn't exist for them. If they had a car it needed repair and wouldn't run. Their apartments were full of old furniture and covered with dust. Books and magazines all over the place." At home they often walked around in the nude, in a curious repetition of Modigliani's fondness for disrobing. Living with Jeanne meant constant theatrical arguments, "very Italian," and family crises played out against a chaotic lifestyle in which parents came and went at unpredictable hours. Jeanne was, as it were, all for her husband, with nothing much left for her children, particularly Laure, in an echo of her mother's attitude. Laure went on to study psychology; her doctoral thesis was the incidence of death among psychotic infants, and also the very rare condition that causes children to mutilate themselves. She is not married and has a daughter, Sarah, now in her twenties. She is unemployed and lives in a working-class quarter of Paris. Haillus believes that Christian Parisot formed a charity and a group of art collectors helps provide for Laure. Her sister Anne, who now lives on a small state pension and is cared for by Haillus, her guardian, does not share in this largesse. One of the reasons why Emanuele fought for Jeanne's legal status had to do with her artistic inheritance. Zborowski and Guillaume had the usual financial arrangement: four-fifths of a work's sale price went to them and one-fifth to the artist or his heirs. Once an artist died it was axiomatic that prices shot up. But when Gerald Reitlinger, author of _The Economics of Taste,_ visited Zborowski's quarters on the rue Joseph Bara in 1922, the Modigliani works were still modestly priced.
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4766, 966, 16122, 390, 39443, 32, 8452, 310, 275, 253, 4766, 32, 187, 187, 510, 1783, 273, 841, 3533, 12957, 326, 253, 3894, 273, 253, 2448, 6782, 3072, 326, 4852, 275, 4766, 14, 20666, 18294, 556, 6137, 25060, 323, 253, 2469, 1740, 8007, 15, 831, 556, 644, 11704, 407, 14257, 4503, 4243, 11438, 598, 285, 1066, 253, 6021, 23465, 15, 496, 643, 3000, 13, 627, 556, 644, 1097, 4780, 285, 9077, 275, 253, 5054, 3708, 273, 2448, 5870, 15, 187, 187, 6436, 13, 4780, 323, 690, 18825, 2390, 556, 644, 1805, 685, 323, 2571, 13, 285, 253, 9077, 323, 690, 2390, 556, 644, 12861, 685, 323, 2571, 15, 380, 20721, 2486, 36710, 313, 1131, 7251, 285, 5662, 582, 7028, 17581, 285, 1110, 342, 247, 6831, 4248, 15, 380, 3897, 398, 2486, 2872, 7747, 13, 440, 38982, 1821, 13, 952, 665, 452, 1620, 7028, 285, 1110, 1293, 247, 6831, 4248, 15, 1797, 4325, 16609, 281, 4332, 13, 627, 369, 4583, 4780, 13, 342, 20721, 562, 9133, 272, 3897, 398, 15, 1723, 13, 432, 6585, 281, 4332, 13, 627, 369, 8069, 642, 1818, 275, 253, 3708, 273, 253, 3072, 4583, 13, 285, 3897, 398, 562, 48085, 20721, 15, 187, 187, 6872, 4342, 20177, 432, 253, 5197, 457, 84, 1783, 273, 941, 432, 253, 31188, 15904, 457, 84, 11604, 30657, 17136, 323, 16609, 281, 4332, 15, 1423, 380, 2173, 941, 5867, 403, 432, 253, 25627, 8404, 285, 19190, 6023, 1338, 5196, 275, 3919, 273, 1016, 807, 15, 496, 436, 1770, 13, 15102, 403, 2546, 281, 2085, 11692, 6021, 941, 323, 253, 16832, 807, 2720, 281, 253, 807, 273, 253, 6630, 15, 1198, 436, 1921, 13, 6021, 941, 275, 436, 1304, 3835, 253, 10333, 281, 4267, 2180, 285, 253, 18825, 941, 3835, 253, 16609, 281, 4332, 2180, 15, 187, 187, 7883, 1680, 10515, 33224, 32, 187, 187, 1552, 2593, 273, 253, 1304, 4648, 941, 327, 11692, 6021, 281, 10957, 7108, 715, 1264, 6021, 246, 4670, 1128, 12973, 13, 4766, 285, 5170, 15, 11279, 432, 271, 5795, 2746, 1128, 8912, 272, 253, 1345, 281, 6266, 3139, 347, 1146, 2406, 13, 4766, 390, 5170, 966, 1128, 609, 5469, 275, 1529, 2593, 273, 253, 1304, 15, 380, 1979, 273, 253, 4766, 13, 1880, 1754, 327, 11692, 38805, 275, 4267, 390, 1754, 327, 1881, 14, 25598, 966, 275, 253, 4050, 6630, 13, 7819, 562, 281, 320, 4829, 8931, 15, 187, 187, 11888, 6021, 347, 253, 17705, 13, 4766, 14, 20666, 18294, 403, 2931, 347, 1110, 342, 247, 1979, 14, 23811, 11692, 6021, 326, 310, 767, 14, 29988, 281, 4021, 253, 4583, 8876, 1979, 14, 23811, 11692, 6021, 15, 3495, 20672, 14, 20666, 18294, 452, 1979, 14, 23811, 38805, 326, 403, 1679, 685, 767, 14, 29988, 273, 253, 8876, 13, 285, 5170, 14, 20666, 18294, 452, 1979, 14, 23811, 38805, 326, 403, 625, 685, 4021, 253, 8876, 15, 187, 187, 510, 13674, 273, 253, 4766, 14, 20666, 30625, 6889, 407, 11692, 1979, 15, 1198, 1264, 14, 10816, 18294, 275, 4267, 13, 253, 4766, 14, 20666, 2491, 310, 670, 370, 1867, 13, 933, 281, 370, 14711, 13, 933, 15, 380, 12714, 273, 247, 11692, 281, 253, 4766, 14, 20666, 30625, 7024, 327, 752, 697, 6021, 310, 5998, 281, 320, 846, 352, 310, 24337, 281, 247, 1264, 14, 10816, 11692, 15, 1348, 329, 11692, 342, 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5886, 281, 253, 4583, 8876, 13, 6889, 689, 673, 15, 496, 4332, 13, 2456, 15, 24, 6, 273, 7747, 313, 1131, 1283, 285, 5662, 10, 6940, 275, 4766, 14, 20666, 18294, 15, 1099, 496, 1180, 13, 326, 37752, 281, 12387, 3041, 7747, 562, 273, 253, 530, 15, 52, 15, 11692, 3072, 273, 28804, 3041, 7747, 15, 1731, 380, 3894, 273, 253, 530, 15, 52, 15, 6782, 3072, 326, 4852, 275, 4766, 14, 20666, 18294, 556, 23028, 689, 673, 15, 496, 16609, 13, 3925, 15, 25, 6, 273, 7747, 6940, 275, 4766, 14, 20666, 18294, 13, 884, 7155, 2792, 625, 685, 275, 4332, 15, 187, 187, 510, 39443, 13, 390, 288, 8165, 562, 13, 273, 253, 4766, 14, 20666, 30625, 556, 644, 11704, 407, 271, 2572, 275, 253, 10764, 273, 253, 6782, 3072, 387, 253, 1029, 285, 1698, 7637, 273, 253, 6021, 3268, 1128, 395, 11467, 4503, 10764, 452, 4395, 598, 390, 1066, 15, 380, 3894, 273, 253, 3072, 275, 253, 5170, 14, 20666, 30625, 556, 28987, 432, 1638, 6, 275, 16609, 281, 1384, 6, 275, 4332, 15, 2058, 253, 1072, 673, 13, 253, 3894, 275, 253, 2406, 14, 20666, 30625, 8899, 432, 2030, 6, 275, 16609, 281, 3285, 6, 275, 4332, 15, 3308, 13, 432, 16609, 281, 4332, 13, 253, 530, 15, 52, 15, 6782, 3072, 556, 2489, 625, 29187, 25865, 1128, 3113, 4942, 625, 275, 253, 1755, 285, 253, 5004, 246, 4670, 13, 285, 11184, 275, 253, 4766, 15, 187, 187, 510, 288, 8165, 273, 253, 4766, 14, 20666, 30625, 556, 644, 247, 11792, 285, 14257, 440, 30933, 264, 1232, 689, 253, 2469, 1740, 8007, 15, 28396, 432, 10333, 13, 1046, 9976, 556, 7402, 342, 247, 4577, 3894, 275, 253, 4766, 14, 20666, 30625, 285, 2169, 10764, 275, 253, 2406, 14, 285, 5170, 14, 20666, 246, 4670, 15, 1621, 2014, 9976, 9572, 562, 347, 1907, 10838, 1025, 253, 4866, 273, 952, 562, 273, 253, 4766, 15, 187, 187, 13641, 3756, 273, 10515, 14, 688, 3188, 2006, 3628, 187, 187, 8457, 253, 5020, 273, 7747, 2965, 715, 253, 4766, 14, 20666, 30625, 13, 253, 5319, 273, 253, 4766, 8800, 247, 2266, 36199, 281, 253, 3072, 4583, 15, 380, 2544, 275, 1110, 5319, 671, 11472, 253, 18825, 2544, 326, 452, 22007, 253, 530, 15, 52, 15, 3072, 1580, 16609, 15, 831, 2593, 37250, 253, 2201, 4342, 28, 253, 7000, 4342, 403, 3559, 275, 17138, 337, 15, 9658, 253, 2234, 7313, 27, 187, 187, 32868, 27, 496, 4332, 13, 760, 884, 6, 273, 4766, 14, 20666, 7747, 574, 417, 12431, 247, 1029, 2143, 11833, 3691, 390, 697, 6425, 285, 4567, 6, 574, 760, 247, 1029, 2143, 11833, 3691, 15, 6295, 10764, 497, 1066, 19836, 432, 16609, 13, 347, 310, 253, 1083, 342, 512, 7747, 15, 2058, 253, 1072, 673, 13, 253, 3894, 273, 4766, 14, 20666, 7747, 342, 690, 6831, 4730, 9461, 432, 1638, 6, 275, 16609, 281, 4567, 6, 275, 4332, 13, 285, 253, 3894, 342, 247, 37589, 457, 84, 4248, 390, 625, 2559, 432, 884, 6, 281, 3436, 7739, 2053, 11701, 275, 11331, 49049, 403, 275, 1386, 342, 253, 9058, 323, 253, 530, 15, 52, 15, 3072, 15, 1630, 187, 187, 19711, 27, 380, 4766, 14, 20666, 1387, 273, 7747, 10652, 8489, 7938, 685, 253, 3072, 432, 16609, 281, 4332, 15, 380, 3894, 273, 4766, 14, 20666, 7747, 7251, 285, 5662, 4829, 25128, 432, 898, 6, 275, 16609, 281, 1668, 6, 275, 4332, 15, 2064, 369, 247, 1199, 17614, 468, 2572, 685, 275, 253, 4583, 3072, 13, 835, 253, 3894, 273, 1110, 11880, 7251, 285, 5662, 9461, 432, 1458, 6, 275, 16609, 281, 1722, 6, 275, 4332, 15, 24646, 13, 253, 3894, 273, 2872, 7747, 13, 11880, 1283, 281, 3285, 13, 275, 253, 4766, 14, 20666, 30625, 6497, 625, 23071, 685, 616, 3894, 275, 253, 3072, 387, 1781, 432, 16609, 281, 4332, 1128, 4064, 1884, 6, 281, 3307, 6, 275, 253, 4766, 14, 20666, 30625, 285, 432, 3349, 6, 281, 3307, 6, 275, 253, 3072, 15, 187, 187, 51, 584, 285, 10570, 79, 5755, 27, 1284, 342, 253, 2120, 6782, 3072, 13, 4766, 14, 20666, 7747, 497, 625, 7393, 1365, 285, 22603, 1037, 11117, 275, 4332, 685, 275, 10226, 15, 1619, 380, 3894, 273, 3032, 4029, 982, 275, 253, 4766, 14, 20666, 3072, 2559, 432, 854, 6, 275, 10226, 281, 2145, 6, 275, 4332, 15, 380, 3894, 273, 19991, 6497, 432, 5096, 6, 275, 10226, 281, 5571, 6, 275, 4332, 347, 253, 3894, 273, 26769, 285, 1284, 2458, 2559, 15, 187, 187, 9709, 5896, 27, 39138, 310, 1679, 1846, 275, 253, 530, 15, 52, 15, 3063, 685, 275, 16609, 13, 285, 436, 310, 11392, 275, 253, 6890, 3894, 273, 4766, 14, 20666, 7747, 665, 403, 7028, 342, 247, 22333, 1246, 15, 9658, 4766, 14, 20666, 7747, 13, 253, 3894, 6497, 432, 10677, 6, 275, 16609, 281, 7288, 6, 275, 4332, 15, 496, 253, 4583, 6782, 3072, 13, 253, 3894, 273, 7028, 952, 342, 247, 22333, 1246, 6497, 432, 10447, 6, 275, 16609, 281, 8073, 6, 275, 4332, 15, 16257, 13, 253, 8394, 273, 4766, 14, 20666, 7747, 665, 452, 1620, 644, 7028, 9461, 432, 1668, 6, 281, 3435, 5294, 13892, 12427, 253, 1818, 275, 253, 2264, 6782, 3072, 15, 187, 187, 56, 12947, 285, 8742, 398, 187, 187, 510, 11792, 5141, 275, 253, 3894, 273, 253, 530, 15, 52, 15, 3072, 326, 310, 275, 253, 4766, 556, 5876, 512, 2201, 18825, 2390, 15, 31565, 273, 4730, 13, 2363, 13, 8645, 13, 7875, 13, 5492, 285, 31908, 13, 253, 3894, 275, 253, 4766, 369, 2057, 3777, 390, 19965, 432, 16609, 281, 4332, 15, 380, 7934, 6517, 281, 436, 4086, 310, 36710, 313, 2082, 285, 5662, 10, 323, 5207, 627, 369, 247, 1534, 10343, 275, 253, 3894, 275, 253, 2406, 14, 20666, 30625, 285, 247, 16613, 6054 ]	years. The median household income in the U.S. when adjusted for the drop in household size increased from $44,845 in 1970 to $59,127 in 2010. That is an increase of 32%, substantially greater than the increase of 13% prior to an adjustment for household size. The effect of adjusting for household size is most pronounced in the 1970s, a decade in which average household size fell from 3.2 to 2.7. As a result, household incomes in this decade are estimated to have increased by 12.2% instead of a mere 1.9% without adjusting for household size. Household size from 2000 to 2010 was virtually unchanged, inching down from 2.6 to 2.5. Thus, adjusting or not adjusting for household size has virtually no impact on income trends in the “lost decade.” Prior to adjustment, median household income in this decade fell by 7.0%. After the adjustment for household size, the drop in household income is 6.6%. The adjusted median household income in 2010—$59,127—is also no higher than its level 13 years earlier in 1997—$59,194. The “lost decade” acquires one other unique characteristic after incomes are adjusted for household size—it is the only 10-year period since 1970 in which median household income at the end of the period has been less than at the start of the period.20 Middle-Income Demography, 1971-2011 Trends in median household income are a good indicator of overall changes in prosperity, but they leave many questions unanswered: Is the rise in prosperity shared equally? Are those in the middle faring as well as those above or below the middle? Are income gaps increasing or decreasing? Is the size of the middle class expanding or shrinking? Who is in the middle? The analysis of these questions reveals that the share of the American adult population that lives in middle-income households has decreased steadily for the past four decades. This has been accompanied by virtually equal parts movements up and down the income ladder. In other words, there has been both progress and regression in the economic status of American families. However, progress for some demographic groups has been better than for others, and the regression for some groups has been deeper than for others. The winners include seniors (ages 65 and older), married couples and those with a college degree. The losers include young adults, unmarried men, people who have never married and those without a college degree.21 From 1971 to 2011, there was overall progress, with winners outnumbering losers. However, from 2001 to 2011, there was effectively no change in the status of the population overall, and losers outnumbered winners. These findings emerge from the Center’s analysis of data from the Census Bureau’s Current Population Survey for 1971 to 2011.22 The specific data analyzed are from the Annual Social and Economic Supplement conducted in March of each year. In this month, respondents are asked to provide household income data for the calendar year prior to the year of the survey. For this reason, income data in this report cover the 1970 to 2010 period and the demographic data cover the 1971 to 2011 period. Who Is Middle Income? This section of the report uses data on household income to divide Americans into three income tiers—lower, middle and upper. Results from an alternative approach—allowing the public to describe itself as being lower, middle or upper class—are discussed in another section of the report. The size of the middle, whether based on household incomes in 2010 or based on self-described class in the 2012 survey, turns out to be nearly identical. Using income as the criterion, middle-income households are defined as those with a size-adjusted household income that is two-thirds to double the overall median size-adjusted household income. 23 Lower-income households have size-adjusted incomes that are less than two-thirds of the median, and upper-income households have size-adjusted incomes that are more than double the median. The boundaries of the middle-income tier vary by household size. For three-person households in 2010, the middle-income range is about $39,000 to $118,000. The assignment of a household to the middle-income tier depends on what its income is estimated to be after it is scaled to a three-person household.24 A household with reported income less than $39,000 may fall in the middle-income tier if it has fewer than three members. Conversely, a household earning more than $39,000 may fall out of the middle-income tier if it has more than three members. Because the median household income has risen over time, the threshold for entering the middle-income tier has also risen over time. From 1970 to 2000, the low end of the middle-income range increased from about $30,000 to $42,000. The threshold fell to $39,000 in 2010 because of the decline in median household income. The precise income ranges used to classify households into the middle-income tier after adjusting for household size are shown in the accompanying table. How Many Adults Are Middle Income? The size of the middle-income tier varies over time because the incomes of individual households, in relation to the overall median, vary over time. In 2011, 50.7% of adults (ages 18 and older) lived in middle-income households.25 In number, that amounted to 117 million adults out of the U.S. household population of 231 million adults.26 The share of the U.S. adult population that lives in middle-income households has diminished over time. In 1971, 60.8% of adults lived in middle-income households, 10 percentage points more than in 2011. The shrinking, or hollowing out, of the middle-income tier has been accompanied by an increase in the shares of the adult population at the high and low ends of the income distribution—and roughly equal shares have moved up or down. The share of the population in the upper-income tier has risen from 14% in 1971 to 20% in 2011. At the same time, the share in the lower-income tier grew from 25% in 1971 to 29% in 2011. Thus, from 1971 to 2011, the U.S. adult population has become more economically polarized—with relatively more in the top and the bottom tiers, and fewer in the middle. The hollowing of the middle-income tier has been a steady and virtually uninterrupted process over the past four decades. Starting from 1970, every decade has ended with a smaller share in the middle-income tier and higher shares in the lower- and upper-income tiers. No single decade stands out as having energized the movement of people out of the middle. Demography of Middle-Income Adults Because the majority of adults fall into the middle-income tier, the characteristics of the middle bear a strong resemblance to the population overall. The changes in those characteristics also mirror the demographic changes that have swept the U.S. population since 1971. This section summarizes the major findings; the detailed findings are presented in Appendix 1. Among the key observations: Education: In 2011, only 10% of middle-income adults had not earned a high school diploma or its equivalent and 32% had only a high school diploma. Both shares were down notably from 1971, as is the case with all adults. At the same time, the share of middle-income adults with some college education rose from 14% in 1971 to 32% in 2011, and the share with a bachelor’s degree or more increased from 10% to 26%. These improvements in educational attainment are in line with the trend for the U.S. population.27 Age: The middle-income group of adults aged somewhat faster than the population from 1971 to 2011. The share of middle-income adults 65 and older nearly doubled from 9% in 1971 to 16% in 2011. That was a much sharper increase than in the overall population, where the share of those ages 65 and older rose from 15% in 1971 to 17% in 2011. Conversely, the share of young adults, ages 18 to 29, in the middle-income tier fell more sharply than their share in the population at large from 1971 to 2011—from 30% to 22% in the middle-income tier and from 28% to 22% in the population. Race and Ethnicity: As with the full adult population, middle-income adults were more racially and ethnically diverse in 2011 than in 1991.28 The share of Hispanics in the middle-income population increased from 8% in 1991 to 13% in 2011. The share of whites fell from 80% in 1991 to 70% in 2011 as the share of blacks and Asians increased. Marriage: Marriage is less common in the U.S. today than in 1971, and this is reflected in the changing share of middle-income adults who are married with a spouse present. Among middle-income adults, the share fell from 74% in 1971 to 55% in 2011. In the overall adult population, the share of married people with a spouse present fell from 69% in 1971 to 52% in 2011. Meanwhile, the proportion of middle-income adults who have never been married rose from 16% to 27%, mimicking the change in the total adult population. Winners and Losers The steady reduction in the share of the U.S. population that is in the middle has affected all major demographic groups. Regardless of education, age, gender, marriage, race and ethnicity, the share in the middle was either reduced or unchanged from 1971 to 2011. The sole exception to this rule is seniors (65 and older) for whom there was a significant decline in the share in the lower-income tier and a notable rise
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64, 67, 64 ]	_b_b_prev = tempVec[3].ptr<float>(0) + i; float* ptr_mean_b_g_prev = tempVec[4].ptr<float>(0) + i; float* ptr_mean_b_r_prev = tempVec[5].ptr<float>(0) + i; float* ptr_mean_a_b_next = tempVec[0].ptr<float>(1) + i; float* ptr_mean_a_g_next = tempVec[1].ptr<float>(1) + i; float* ptr_mean_a_r_next = tempVec[2].ptr<float>(1) + i; float* ptr_mean_b_b_next = tempVec[3].ptr<float>(1) + i; float* ptr_mean_b_g_next = tempVec[4].ptr<float>(1) + i; float* ptr_mean_b_r_next = tempVec[5].ptr<float>(1) + i; float* ptr_I = I.ptr<float>(0) + i; float* ptr_q_b = q.ptr<float>(0) + i * 3; float* ptr_q_g = q.ptr<float>(0) + i * 3 + 1; float* ptr_q_r = q.ptr<float>(0) + i * 3 + 2; float sum_mean_a_b = ptr_mean_a_b_prev (r + 1); float sum_mean_a_g = ptr_mean_a_g_prev (r + 1); float sum_mean_a_r = ptr_mean_a_r_prev (r + 1); float sum_mean_b_b = ptr_mean_b_b_prev (r + 1); float sum_mean_b_g = ptr_mean_b_g_prev (r + 1); float sum_mean_b_r = ptr_mean_b_r_prev (r + 1); for (int j = 1; j <= r; j++) { sum_mean_a_b += ptr_mean_a_b_next; sum_mean_a_g += ptr_mean_a_g_next; sum_mean_a_r += ptr_mean_a_r_next; sum_mean_b_b += ptr_mean_b_b_next; sum_mean_b_g += ptr_mean_b_g_next; sum_mean_b_r += ptr_mean_b_r_next; ptr_mean_a_b_next += step; ptr_mean_a_g_next += step; ptr_mean_a_r_next += step; ptr_mean_b_b_next += step; ptr_mean_b_g_next += step; ptr_mean_b_r_next += step; } ptr_q_b = (sum_mean_a_b ptr_I + sum_mean_b_b) div; ptr_q_g = (sum_mean_a_g ptr_I + sum_mean_b_g) div; ptr_q_r = (sum_mean_a_r ptr_I + sum_mean_b_r) div; ptr_I += step; ptr_q_b += step * 3; ptr_q_g += step * 3; ptr_q_r += step * 3; for (int j = 1; j <= r; j++) { sum_mean_a_b += ptr_mean_a_b_next - ptr_mean_a_b_prev; sum_mean_a_g += ptr_mean_a_g_next - ptr_mean_a_g_prev; sum_mean_a_r += ptr_mean_a_r_next - ptr_mean_a_r_prev; sum_mean_b_b += ptr_mean_b_b_next - ptr_mean_b_b_prev; sum_mean_b_g += ptr_mean_b_g_next - ptr_mean_b_g_prev; sum_mean_b_r += ptr_mean_b_r_next - ptr_mean_b_r_prev; ptr_mean_a_b_next += step; ptr_mean_a_g_next += step; ptr_mean_a_r_next += step; ptr_mean_b_b_next += step; ptr_mean_b_g_next += step; ptr_mean_b_r_next += step; ptr_q_b = (sum_mean_a_b ptr_I + sum_mean_b_b) div; ptr_q_g = (sum_mean_a_g ptr_I + sum_mean_b_g) div; ptr_q_r = (sum_mean_a_r ptr_I + sum_mean_b_r) div; ptr_I += step; ptr_q_b += step * 3; ptr_q_g += step * 3; ptr_q_r += step * 3; } for (int j = r + 1; j < img_row - r - 1; j++) { sum_mean_a_b += ptr_mean_a_b_next - ptr_mean_a_b_prev; sum_mean_a_g += ptr_mean_a_g_next - ptr_mean_a_g_prev; sum_mean_a_r += ptr_mean_a_r_next - ptr_mean_a_r_prev; sum_mean_b_b += ptr_mean_b_b_next - ptr_mean_b_b_prev; sum_mean_b_g += ptr_mean_b_g_next - ptr_mean_b_g_prev; sum_mean_b_r += ptr_mean_b_r_next - ptr_mean_b_r_prev; ptr_mean_a_b_prev += step; ptr_mean_a_g_prev += step; ptr_mean_a_r_prev += step; ptr_mean_b_b_prev += step; ptr_mean_b_g_prev += step; ptr_mean_b_r_prev += step; ptr_mean_a_b_next += step; ptr_mean_a_g_next += step; ptr_mean_a_r_next += step; ptr_mean_b_b_next += step; ptr_mean_b_g_next += step; ptr_mean_b_r_next += step; ptr_q_b = (sum_mean_a_b ptr_I + sum_mean_b_b) div; ptr_q_g = (sum_mean_a_g ptr_I + sum_mean_b_g) div; ptr_q_r = (sum_mean_a_r ptr_I + sum_mean_b_r) div; ptr_I += step; ptr_q_b += step * 3; ptr_q_g += step * 3; ptr_q_r += step * 3; } for (int j = img_row - r - 1; j < img_row; j++) { sum_mean_a_b += ptr_mean_a_b_next - ptr_mean_a_b_prev; sum_mean_a_g += ptr_mean_a_g_next - ptr_mean_a_g_prev; sum_mean_a_r += ptr_mean_a_r_next - ptr_mean_a_r_prev; sum_mean_b_b += ptr_mean_b_b_next - ptr_mean_b_b_prev; sum_mean_b_g += ptr_mean_b_g_next - ptr_mean_b_g_prev; sum_mean_b_
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336, 66, 11, 285, 475 ]	lines differ from pol lines in their mitochondrial genome organization, suggesting that 681A might be a variant of pol CMS. On the other hand, restorers for hau cytoplasm have not been identified so far and pol or nap restorers fail to rescue hau-induced male sterility ([@b90-64_38]). Another novel CMS gene, orf288, co-transcribed with atp6 was discovered in hau CMS ([@b43-64_38]). Orf288 was cytotoxic to E. coli and induced male sterility in A. thaliana when expressed from the nuclear genome with or without the mitochondrial targeting presequences ([@b43-64_38]). It was further shown that ORF288 protein was targeted to the mitochondria even when not fused with mitochondrial targeting presequence. These results indicate that orf288 might be the causal gene of hau CMS. Recent studies on R. sativus discovered types of CMS other than Ogura CMS. One was found in Korean radish collections and named NWB CMS ([@b70-64_38]); the Rf genes for this CMS have not yet been found. Another one was found in a radish of Uzbekistan ([@b44-64_38], [@b55-64_38], [@b56-64_38]). A study of the complete mitochondrial genome sequence of this CMS type, designated as DCGMS, identified the causal gene as a novel chimeric gene, orf463, consisting of a 128-bp partial sequences of coxI and a 1261-bp sequence of unclear origin ([@b72-64_38]). [@b34-64_38] hybridized two distantly related accessions of A. thaliana and obtained male sterile strains whose inheritance pattern in reciprocal crosses suggested CMS. Mitochondrial genome analyses of the two accessions revealed that the causal gene of this CMS was orf117. The predicted ORF117 peptide is 56% identical and 69% similar to the ORF108 peptide from Moricandia arvensis that induces male sterility in B. juncea (see next section). (2) Alloplasmic CMS as a result of interspecific or intergeneric hybridizations ------------------------------------------------------------------------------- Since the establishment of the CMS line of B. rapa with the cytoplasm of Diplotaxis muralis ([@b38-64_38]), several more male sterile lines have been developed in Brassicaceae ([Table 1](#t1-64_38){ref-type="table"}). In B. juncea, the most important oil seed crop in Southern Asia, the cytoplasms of at least eight species induce CMS ([@b3-64_38], [@b53-64_38], [@b54-64_38], [@b64-64_38], [@b73-64_38], [@b77-64_38], [@b79-64_38], [@b82-64_38]). In addition to D. muralis, four other cytoplasms induce CMS in B. rapa ([@b22-64_38], [@b65-64_38], [@b76-64_38], [@b77-64_38], [@b89-64_38]). Seven B. napus CMS lines are known, including the three (Ogura, pol and nap) mentioned above. The cytoplasm of D. muralis induces sterility also in B. oleracea ([@b84-64_38]). Erucastrum canariense and M. arvensis cytoplasms were recently reported to confer CMS in B. oleracea ([@b17-64_38]). A CMS line of R. sativus with the cytoplasm of B. maurorum was produced ([@b2-64_38]). As shown in [Table 1](#t1-64_38){ref-type="table"}, five species, B. oxyrrhina, B. tournefortii, D. muralis, D. siifolia and Enarthrocarpus lyratus, are effective as donors of male sterile cytoplasm for more than one crop species. The cytoplasm of D. muralis induces male sterility in B. rapa, B. oleracea and B. napus, whereas En. lyratus cytoplasm confers CMS in B. rapa, B. juncea and B. napus. CMS was also obtained in B. juncea as a result of interspecific hybridization between B. rapa and B. juncea; this CMS was later transferred to leaf mustard (B. juncea var. multiceps) ([@b101-64_38]), tuber mustard (B. juncea var. tumida) ([@b107-64_38]) and stem mustard (B. juncea) ([@b103-64_38]). Male sterility in B. juncea CMS line was found to be associated with a novel gene, orf220, which shares 79 homology with orf222 (nap) and 81% with orf224 (pol) of B. napus ([@b101-64_38]). Three cytoplasms (D. berthautii, D. catholica and D. erucoides) that confer CMS to B. juncea commonly possess orf108 upstream of atpA, and the two genes are co-transcribed. Expression analyses suggested orf108 as the causal gene in these CMS sources ([@b53-64_38]). Orf108 was also found in male sterile B. juncea obtained by cell fusion between B. juncea and M. arvensis. The CMS B. juncea line derived from the somatic hybridization with M. arvensis carried the unaltered mitochondrial genome from M. arvensis in which orf108 is present ([@b78-64_38]). The finding is the first demonstration of a common molecular mechanism underlying CMS in lines of different origin ([@b1-64_38], [@b53-64_38]). Apart from the above species, orf108 was also found in other wild species including B. oxyrrhina, Sinapis alba, En. lyratus and D. tenuisilque, which suggests its wide distribution. However, orf108 was absent in D. muralis, D. siifolia and D. cretasia. Therefore, it appears that orf108 is of ancestral origin but is lost or modified in some lineages. Recent finding in A. thaliana of CMS-associated orf117 with 69% homology to orf108 ([@b34-64_38]) further supports this view. Orf263 was inferred to be the causal gene in the CMS lines of B. napus and B. juncea with the cytoplasm of B. tournefortii ([@b54-64_38]). In the mitochondria of D. muralis, which induces CMS in three Brassica species ([Table 1](#t1-64_38){ref-type="table"}), a novel chimeric gene, orf72, located downstream of rps7 and containing a fragment of atp9, was identified. Comparison of gene expression and pollen fertility demonstrated the association of the orf72 with CMS ([@b84-64_38]). (3) CMS plants obtained by cell fusion -------------------------------------- In contrast to sexual hybridization, cell fusion does not require fertilization, and thus a much wider range of hybridization species can be used. Wild species not used in interspecific and intergeneric sexual hybridization have been used for cell fusion to produce male sterile lines ([Table 2](#t2-64_38){ref-type="table"}). In addition to B. tournefortii, D. catholica, M. arvensis and R. sativus, which have been used as cytoplasm donors in sexual hybridization, A. thaliana, Orychophragmus violaceus, Sinapis arvensis and Trachystoma ballii cytoplasms were transferred into B. napus, B. juncea or B. oleracea by somatic cell fusion to obtain CMS ([@b27-64_38], [@b28-64_38], [@b29-64_38], [@b39-64_38], [@b45-64_38], [@b46-64_38], [@b47-64_38], [@b48-64_38], [@b66-64_38], [@b97-64_38], [@b99-64_38], [@b98-64_38]). Whereas alloplasmic CMS lines obtained by sexual hybridization inherit the mitochondrial genome of the female parent, somatic hybridization can give rise to novel recombined mitochondrial genomes derived from both parental species, which complicates identification of CMS causal genes. Hitherto, two genes have been identified that demonstrate contrasting features in relation to the CMS genes of alloplasmic lines. The progeny of somatic hybrid between B. juncea and *
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1214, 12185, 11018, 2351, 1092, 390, 13345, 4753, 1008, 435, 11232, 64, 72, 1761, 17866, 17, 28, 1214, 435, 11232, 64, 72, 1761, 17866, 28, 1214, 435, 11232, 64, 72, 1761, 17866, 19, 28, 1214, 22468, 5120, 18, 28, 1214, 22468, 5120, 19, 28, 1214, 22468, 5120, 20 ]	operations. In the Pentagon and Whitehall, it has become a critical component of a diplomatic and military campaign to blockade, isolate and weaken Iran by hyping its “nuclear threat”: a phrase now used incessantly by Barack Obama and Gordon Brown, and parroted by the BBC and other broadcasters as objective news. And it is fake." Your more recent attempts to convince the public to support yet another military aggression in the Middle East, with the millions of innocent lives that would be lost as a result, are just as sinister. Last week you claimed that Iran had been "caught red-handed...by the forced disclosure". I beg your pardon? You condemn Iran for doing its job, declaring a facility to the IAEA and inviting its inspectors in! And the conclusion you reach is that they've "been caught lying, again"? Incredible from someone supposed to be unbiased. Yesterday you continued in the same vein, writing of "disclosures concerning Iran's alleged attempts to design a nuclear warhead to be mounted on its Shahab long-range missiles that are capable of striking Israel and some European countries." You continue with some conspiracy theory about how the IAEA is hiding this information from the public "for fear of increasing international tensions." Your source for this claim was the NYT,but you didn't pass on their caveat: "its conclusions are tentative and subject to further confirmation of the evidence, which it says came from intelligence agencies...". Why not? This is outrageous, yet again, presenting as fact unsubstantiated claims. Neither was there any mention of El Baradei's recent statement reported by your own newspaper that there is "no credible evidence" that Iran is developing nuclear weapons". 01 October 2009 In his latest column for the New Statesman, John Pilger compares the current drum-beating for war against Iran, based on a fake "nuclear threat", with the manufacture of a sense of false crisis that led to invasion of Iraq and the deaths of 1.3 million people. It's not only Pilger though who's denouncing the British, American and Israeli lies trying to push us all once again into yet another war of aggression. There's also Phillip Giraldi (WMD All Over Again) who shows just how co-ordinated an effort there is really going on in the US, specifically the media - Washington Post - and across the political divide. He also reveals what the ulterior motive for sanctions really is: "sanctions are an extremely blunt instrument. In practice they never work and only solidify support for a rogue regime, witness Cuba. Once sanctions are in place negotiations cease, virtually guaranteeing a slide to war, which is precisely what Howard Berman and The Washington Post would like to see develop." And Washington, London and Tel Aviv... He finishes "Remember the WMD, pilotless drones, chemical weapon labs, and mushroom clouds? The same song is being sung again, but this time everyone should recognize a con job when they see it coming." Then there's Glenn Greenwald (Talking about Iran on the TV) who debated on MSNBC with Washington Post Editorial Page writer Jonathan Capehart ("fresh back from Israel" - where he presumable refined his talking points...well, refined may not accurately describe those comments, but anyway) and Arianna Huffington: It's important to note Greenwald's comments that "the entire time when I was speaking, MSNBC was flashing scary video of Iran testing its missiles (though it omitted video of this and this), interspersed with this melodramatic and frightening caption: It’s genuinely hard to overstate the effect of visuals like this, transmitted over and over and over to a population." Greenwald leads us to Scott Ritter's interview on Democracy Now (Politically Motivated Hype). Scott Ritter was former UN weapons inspector in Iraq from 1991-1998: "Iran is a signatory to the Nuclear Non-Proliferation Treaty. It has a complete inspection regime conducted by the International Atomic Energy Agency. It’s not been found to be in noncompliance. And yet, here we are condemning Iran for doing its job, declaring a facility, inviting inspectors in. And the conclusion it’s reached from this? That they’re producing nuclear weapons. This is politically motivated hype designed to create a situation this coming Thursday that will find the United States unable to reach any sort of agreement with Iran about its nuclear program....if you’re the Iranians and you make a decision that you strategically require an additional source of energy, such as nuclear energy, to supplement your domestic energy usage so that you free up your oil production and gas production for exportation, so you can earn money, this is a big deal. This isn’t insignificant. And so, you’re building this capability. Israel and the United States say they want to bomb it. What do you do? Well, the first thing you do is you build redundancy, and that’s what this new Qom facility represents. It’s redundancy. It’s a backup to the Natanz primary facility. Again, it’s been declared, no nuclear material has been diverted. But it’s there as a backup. The second thing you do is you fire off missiles in a warning that you have an inherent right and capability of self-defense. Israel launched a massive air exercise last year, in which it demonstrated the ability to fly hundreds of aircraft, you know, the distance necessary to strike targets in Iran. The United States is carrying out exercises with Israel as we speak. You know, the bottom line is it’s the United States and Israel which are the more aggressive of the players here. Iran is not an aggressor. Iran has not attacked anybody. Iran is simply trying to do that which it is legally allowed to do: produce enriched uranium for the purposes of nuclear power. It’s Israel, which, by the way, is not a signatory to the Nuclear Non-Proliferation Treaty, claims it will never be a signatory and has a massive nuclear weapons capability—it’s Israel and the United States which are creating a crisis out of nothing. " And finally all this is backed up by outgoing IAEA chief Mohamed ElBaradei ( "no credible evidence" that Iran is developing nuclear weapons). The release of the famous EU report on last years Georgia-South Ossetia conflict which manages to find both sides at fault! Georgia for starting the conflict and wait for it, Russia for 'retaliation' “far beyond the reasonable limits of defense”. Perhaps they ought to have a look at the Afghan and Iraqi conflicts too, or perhaps even the recent Israeli genocide in Gaza...it would make interesting reading if they kept to the same criteria! Shocking seems to be the word of the day considering this next item that Borev flagged: "RAF leaflet box kills Afghan girl". "The box should have broken apart in mid-air but struck the young girl intact." Note the scary comment under the photo 'The RAF tries to reach local people with leaflet drops'. No one can say they didn't reach that little girl, who remains nameless, no British paper has yet published her name and only the Daily Mail has published her age. She was 6 years old. If it had been a British girl we would akready know everything about her and her life. I have checked the BBC, Guardian, Telegraph, Times, Scotsmantwice, Sky News - there's nothing on her name - while the Independent thought it only important enough as a 3 liner at the very end of the ousted US diplomat report above. Disgusting behaviour by the British press. Yet again. Pages About Me "I never meant to say that the Conservatives are generally stupid. I meant to say that stupid people are generally Conservative. I believe that is so obviously and universally admitted a principle that I hardly think any gentleman will deny it. " -- John Stuart Mill "The crimes of the United States have been systematic, constant, vicious, remorseless, but very few people have actually talked about them. You have to hand it to America. It has exercised a quite clinical manipulation of power worldwide while masquerading as a force for universal good. It's a brilliant, even witty, highly successful act of hypnosis." ---- abstract: 'Driving a quantum system periodically in time can profoundly alter its long-time dynamics and trigger topological order. Such schemes are particularly promising for generating non-trivial energy bands and gauge structures in quantum-matter systems. Here, we develop a general formalism that captures the essential features ruling the dynamics: the effective Hamiltonian, but also the effects related to the initial phase of the modulation and the micro-motion. This framework allows for the identification of driving schemes, based on general $N$-step modulations, which lead to configurations relevant for quantum simulation. In particular, we explore methods to generate synthetic spin-orbit couplings and magnetic fields in cold-atom setups.' author: - 'N. Goldman' - 'J. Dalibard' title: \| [Periodically-driven quantum systems:\ Effective Hamiltonians and engineered gauge fields]{} --- Introduction ============ Realizing novel states of matter using controllable quantum systems constitutes a common interest, which connects various fields of condensed-matter physics. Two main routes are currently investigated to reach this goal. The first method consists in fabricating materials [@topological; @superconductivity], or artificial materials [@artificial_graphene0; @artificial_graphene; @artificial_graphene2; @photonic1; @photonic2; @photonic3
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4695, 374, 13, 22, 495, 374, 337, 13, 22, 337, 470, 13, 22, 470, 23257, 13589, 27, 4358, 26041, 284, 15, 1997, 1757, 11125, 820, 2145, 15, 330, 10449, 42, 18100, 14, 9873, 1831, 7860, 5271, 3876, 3691, 19804, 1448, 33042, 1448, 399, 2271, 27560, 284, 42924, 15333, 4474, 247, 21000, 9725, 8441, 7544, 6752, 5826, 4695, 374, 13, 22, 495, 374, 337, 13, 22, 337, 470, 13, 22, 470, 23257, 13589, 27, 4358, 26041, 284, 15, 3905, 2611, 33271, 546, 826, 9374, 279, 64, 13017, 15, 527, 69, 23512, 854, 16, 1093, 16, 2693, 374, 27, 1619 ]	Marcela Muñoz Ávila 179 Los siguientes gráfi cos representan la información del cuadro anterior por institución y por años: Gráfi co 3. CDA-Corporación para el Desarrollo Sostenible del Norte y oriente Amazónico Consultas realizadas por año 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 10 12 8 6 4 2 0 Fuente: las autoras. Gráfi co 4. CODECHOCÓ-Corporación Autónoma Regional para el Desarrollo Sostenible del Chocó Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. La participacion en la gestion_final.indd 179 8/18/09 2:28 PM La participación en la gestión ambiental: un reto para el nuevo milenio 180 Gráfi co 5. CORPAMAG-Corporación Autónoma Regional del Magdalena Consultas realizadas por año 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 6. CARDIQUE-Corporación Autónoma Regional del Canal del Dique Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 7. CORPOGUAJIRA-Corporación Autónoma Regional de la Guajira Consultas realizadas por año 1993 1996 1999 2002 2005 2008 0,8 1 0,6 0,4 0,2 0 Fuente: las autoras. La participacion en la gestion_final.indd 180 8/18/09 2:28 PM Gloria Amparo Rodríguez, Lina Marcela Muñoz Ávila 181 Contrastando la información anterior se tiene que las Corporaciones Autónomas Regionales que reportan la realización de consultas con comunidades negras son Cardique, Codechocó, Corpocesar, CVC, Corantioquia y Corpourabá. Las demás aseguran haber realizado sus consultas únicamente con pueblos indígenas. 4.2. Audiencias públicas e intervención de terceros en el otorgamiento de licencias ambientales De la información obtenida sobre audiencias públicas realizadas por el Ministerio de Ambiente, Vivienda y Desarrollo Territorial en el otorgamiento de licencias ambientales se tiene un total de 51 proyectos relacionados por la información ofi cial, divididos en 10 categorías, de la siguiente manera: Cuadro 19. Sector Número de audiencias públicas por sector Hidrocarburos Energéticos Minería Viales Puertos y navegación Plantas de tratamiento y producción Aeroportuarios Relleno Ríos Turísticos Total 11 8 9 7 5 3 3 2 2 1 51 Fuente: las autoras. La participacion en la gestion_final.indd 181 8/18/09 2:28 PM La participación en la gestión ambiental: un reto para el nuevo milenio 182 La anterior información se expresa de forma gráfi ca así: Gráfi co 8. Ministerio de Ambiente, Vivienda y Desarrollo Territorial Audiencias públicas. 1994-2008 Plantas de trat. y prod. Aeroportuario Relleno Rio Tusristicos Hidrocarburos Energéticos Minería Viales Puerto y navegación Cantidad 12 10 8 6 4 2 0 11 8 9 7 5 3 3 2 2 1 Fuente: las autoras. Los anteriores datos señalan nuevamente que los sectores en donde más se presentan audiencias públicas son el de hidrocarburos y el energético, fenómeno que puede ocurrir por el número de solicitudes de licencias ambientales y por la importancia económica y social que representan este tipo de sectores. A continuación se presenta un patrón histórico del número de audiencias públicas que se han realizado por años en el Ministerio de Ambiente, Vivienda y Desarrollo Territorial, según los resultados de la investigación: Gráfi co 9. Ministerio de Ambiente, Vivienda y Desarrollo Territorial. 1994-2008 Consultas realizadas por año 1993 1996 1999 2002 2005 2008 10 12 14 8 6 4 2 0 1 11 3 33 3 3 13 4 4 66 Fuente: las autoras. La participacion en la gestion_final.indd 182 8/18/09 2:28 PM Gloria Amparo Rodríguez, Lina Marcela Muñoz Ávila 183 Desde 1993 hasta el año 2000 se realizaron 36 audiencias públicas ambientales por parte del Ministerio de Ambiente, Vivienda y Desarrollo Territorial, mientras que de 2001 a mediados de 2008 ese número disminuyó a 15, de acuerdo con los datos suministrados por las instituciones, lo que demuestra una disminución importante de la utilización de este mecanismo en los últimos años. En términos porcentuales, el siguiente cuadro expresa, de un total de 51 audiencias públicas, cuántas se realizaron por año: Cuadro 20. A ño Número de audiencias Porcentaje 1994 1 1,9% 1995 13 25,49% 1996 4 7,8% 1997 3 5,8% 1998 6 11,7% 1999 6 11,7% 2000 3 5,8% 2001 3 5,8% 2002 1 1,9% 2003 - 2004 3 5,8% 2005 - 2006 4 7,8% 2007 3 5,8% 2008 1 1,9% Fuente: las autoras. Como se ha planteado en este documento, la autoridad puede convocar a la audiencia pública de ofi cio; sin embargo, en el análisis que hemos efectuado encontramos que son escasas, por no decir casi nulas, las audiencias públicas que se dan de esta forma. Llamamos la atención de las autoridades ambientales para que en casos donde se presentan confl ictos con relación a proyectos, donde la información es escasa, para que de manera oportuna y sin necesidad La participacion en la gestion_final.indd 183 8/18/09 2:28 PM La participación en la gestión ambiental: un reto para el nuevo milenio 184 de requerimientos se convoque la realización de audiencias públicas. De esta forma se puede, además de ofrecer información, minimizar los problemas y aclarar la realización de estos proyectos. En cuanto a las Corporaciones Autónomas Regionales,12 desde 1994 hasta mediados de 2008 se han realizado 164 audiencias públicas. Cinco corporaciones reportan no haber realizado ninguna audiencia en 15 años y las que más reportan se observan en el siguiente cuadro: Cuadro 21. Corporaciones autónomas regionales y de desarrollo sostenible con el mayor número de audiencias públicas realizadas Número de audiencias públicas realizadas por corporación CRC CAR-CUNDINAMARCA CVC CARDIQUE CORANTIOQUIA CORPONARIÑO 58 15 10 9 6 6 Fuente: las autoras. La anterior información se expresa en forma gráfi ca, por institución y por años, así: Gráfi co 10. CRC-Corporación Autónoma Regional del Cauca Consultas realizadas por año 1993 1996 1999 2002 2005 2008 25 20 15 10 5 0 Fuente: las autoras. 12 Análisis sin información de tres Corporaciones Autónomas Regionales. La participacion en la gestion_final.indd 184 8/18/09 2:28 PM Gloria Amparo Rodríguez, Lina Marcela Muñoz Ávila 185 Gráfi co 11. CAR-Corporación Autónoma Regional de Cundinamarca Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 12. CVC-Corporación Autónoma Regional del Valle del Cauca Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 13. CARDIQUE-Corporación Autónoma Regional del Canal del Dique Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. La participacion en la gestion_final.indd 185 8/18/09 2:28
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3655, 13, 48190, 9, 18, 582, 18450, 322, 15, 38, 15, 19, 69, 721, 3763, 313, 7199, 481, 1723, 13, 1964, 739, 590, 31658, 1057, 417, 4647, 281, 21248, 390, 44245, 16966, 13, 390, 16966, 273, 8767, 7467, 15, 4031, 15, 187, 688, 436, 1083, 13, 5466 ]	missing out, the fear of being flamed or forgotten’. Andreas not only regards these fears as justifiable, he traces them back to the rationalism of the Enlightenment and the French Revolution. The Reign of Terror, he thinks, anticipated ‘the terrors of technocracy, which sought to liberate humanness through the efficiency of markets and the rationalism of machines’. The leaps of logic in this passage are not entirely explained by the fact that the guilt-wracked Andreas is, at this late stage of the novel, beginning to lose his mind. Even someone not functioning at full mental capacity could probably come up with at least a couple of reasons why the prospect of running afoul of the Stasi is substantially different to the fear of becoming unpopular or uncool. Yet the categorical confusion appears to belong not simply to Andreas, but to the novel itself. Purity sees the implications of technology in moral and psychological terms. It casts the Internet as a perverter of reality, a symbol of dissolution and death, rather than a new reality to be negotiated. It shows no real interest in the way that information technology or a WikiLeaks-like operation might actually work, or in the fact that the issues raised by the likes of Julian Assange and Edward Snowden are not moral and psychological, but ethical and political. The real potential for the Internet to become ‘totalitarian’ is that makes it possible for governments and corporations to collect vast amounts of personal data at a level of detail unimagined by the Stasi. Purity is not concerned with this question, though it does come down on the side of an orderly public sphere overseen by responsible journalists. Leila, the novel’s most forceful critic of the Sunlight Project, condemns Andreas’s operation for its savage naïveté, like the kid who thinks adults are hypocrites for filtering what comes out of their mouths. Filtering isn’t phoniness – it’s civilization … Andreas Wolf is a man so full of his own dirty secrets that he sees the entire world as dirty secrets. The dissolution of Andreas Wolf would appear to validate this judgement. But in doing so, it also suggests why Purity’s critique of our media-saturated, technology-crazed, apocalypse-haunted historical moment is so thin, why its argument between traditional journalism and new media is a damp squib. Near the end of the book, Andreas becomes so immersed and implicated in the Internet, so enmeshed in its totalitarianism, that his online existence was coming to seem realer than his physical self … The aim of the Internet and its associated technologies was to ‘liberate’ humanity from the tasks – making things, learning things, remembering things – that had previously given meaning to life and thus had constituted life. Now it seemed as if the only task that meant anything was search-engine optimization. The novel seems to want us to treat this kind of lame pronouncement as a serious criticism. What Purity seems unable or unwilling to do, however, is distinguish between a material criticism of the world we live in and the novelistic conceit that casts the Internet as the symbol of a psychologically destructive infinity. Near the end of Freedom, there is a line that might be read as a keynote: The personality susceptible to the dream of limitless freedom is a personality also prone, should the dream ever sour, to misanthropy and rage. One could substitute the word ‘purity’ for ‘limitless freedom’ and the line could slot happily into in Franzen’s new novel, though Purity ups the ante by suggesting that the price of such idealism extends beyond mere misanthropy and rage to neurosis and psychological breakdown. It does so with considerable ingenuity. What it doesn’t do is tell us anything in particular about modern technology. 725 S.E.2d 336 (2012) 314 Ga. App. 628 SECURED REALTY & INVESTMENTS, INC. et al. v. BANK OF NORTH GEORGIA. Bank of North Georgia v. Secured Realty & Investments, Inc. et al. Nos. A11A2020, A11A2021. Court of Appeals of Georgia. March 7, 2012. 338 Charles Merritt Lane, Carrollton, for appellants. Stokes, Lazarus & Carmichael, William Kim Carmichael, Atlanta, Rachel Humphrey, for appellee. McFADDEN, Judge. These appeals arise from a bank's lawsuit to collect amounts due on two promissory notes given or guaranteed by the debtors. The trial court denied summary judgment to the bank as to one of the notes and granted summary judgment to the bank as to the other note. Because there are no genuine issues of material fact, we affirm the grant of summary judgment and reverse the denial. "Summary judgment is proper when there is no genuine issue of material fact and the movant is entitled to judgment as a matter of law. We review the grant of summary judgment de novo, construing the evidence in favor of the nonmovant." (Citations and punctuation omitted.) Brooks v. Gwinnett Community Bank, 311 Ga.App. 806, 717 S.E.2d 647 (2011). So construed, the evidence shows that Secured Realty Investments, Inc. (Secured), executed a promissory note, identified as Note 20, in favor of Bank of North Georgia ("BNG") in the principal sum of $911,557, and Dennis McDowell personally guaranteed the note. Secured also executed another promissory note, identified as Note 21, in favor of BNG in the principal amount of $3.8 million, and McDowell personally guaranteed that note as well. Secured and McDowell defaulted and failed to pay the amounts due to BNG under the terms of the notes and guarantees. BNG sued Secured and McDowell to collect the amounts due. BNG subsequently moved for summary judgment, filing the affidavit of its senior vice-president, along with documentary evidence, which set forth the parties' contracts and accounts, the debtors' defaults and their total debt to BNG. After a hearing, the trial court denied summary judgment to the bank as to Note 20 and granted summary judgment as to Note 21. In Case No. A11A2020, Secured and McDowell appeal from the grant of summary judgment on Note 21; and in Case No. A11A2021, BNG appeals from the denial of summary judgment on Note 20. Case No. A11A2020 1. Secured and McDowell contend that the trial court erred in granting summary judgment in favor of the bank because genuine issues of material fact remain as to their affirmative defenses. The contention is without merit. Under OCGA § 9-11-56, BNG had the burden on its motion for summary judgment to establish that there is no genuine issue of fact and that it is entitled to judgment as a matter of law. Lau's Corp. v. Haskins, 261 Ga. 491, 405 S.E.2d 474 (1991). Where, as here, the record shows that the promissory notes and guarantees were duly executed by the debtors and that they are in default, a prima facie right to judgment as a matter of law was established, and the burden shifted to Secured and McDowell to produce or point to evidence in the record which established an affirmative defense. Helton v. Jasper Banking Co., 311 Ga.App. 363, 363-364, 715 S.E.2d 765 (2011); Reece v. Chestatee State Bank, 260 Ga.App. 136, 138(1), 579 339 S.E.2d 11 (2003); Miller v. Calhoun/Johnson Co., 230 Ga.App. 648, 649-650(3)(b), 497 S.E.2d 397 (1998). In response to the bank's motion for summary judgment, Secured and McDowell were not entitled to rest on allegations in their pleadings to establish affirmative defenses on which they would have the burden of proof at trial, but were required to come forward with or point to specific facts in the record to establish affirmative defenses. Southeast Reducing Co. v. Wasserman, 229 Ga.App. 1, 4-5(2), 493 S.E.2d 201 (1997). Secured and McDowell failed to point to such specific facts establishing a triable issue as to their affirmative defenses of estoppel and breach of the implied covenant of good faith and fair dealing. (a) "In order for an equitable estoppel to arise, there must generally be some intended deception in the conduct or declarations of the party to be estopped, or such gross negligence as to amount to constructive fraud, by which another has been misled to his injury." (Citation and punctuation omitted.) Griffin v. State Bank of Cochran, 312 Ga.App. 87, 94(2)(a), 718 S.E.2d 35 (2011). Similarly, under the doctrine of promissory estoppel, "[a] promise which the promisor should reasonably expect to induce action or forbearance on the part of the promisee or a third person and which does induce such action or forbearance is binding if injustice can be avoided only by enforcement of the promise." (Citation and punctuation omitted.) Georgia Investments Intl. v. Branch Banking & Trust Co., 305 Ga.App. 673, 675(1), 700 S.E.2d 662 (2010). However, promissory estoppel does not apply to vague or indefinite promises, or promises of uncertain duration. Id. In this case, Sec
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19485, 689, 253, 1533, 672, 253, 2656, 5439, 521, 4430, 187, 328, 306, 4837, 521, 6422, 25033, 40602, 15, 380, 643, 17373, 33766, 1066, 275, 247, 861, 273, 1675, 15, 187, 2302, 13, 2656, 574, 347, 1199, 6265, 347, 7728, 316, 15, 187, 11564, 253, 33764, 388, 3525, 13, 253, 4475, 273, 7728, 316, 13, 369, 347, 12368, 11574, 347 ]	such as hotels, restaurants, and entertainment venues. Studies have shown that the migrant population tends to have lower educational attainment, lower income, and lower access to health services compared to permanent residents who hold a hukou. Most migrants are sexually active and are vulnerable to HIV and other STIs. A study in Guangdong found that the HIV awareness rate among the migrant population was only 49%, that 8% of the participants had extramarital sex in the last year and that only 72% of them used condoms in their most recent extramarital sexual contact (Liu et al. [@CR18]). A study in Foshan city showed that HIV awareness and risk behavior varied for different occupations among the migrant population. HIV awareness was particularly low among workers in the entertainment, restaurant, and construction industries. The study also showed that 31% had engaged in commercial sex and 9% reported non-commercial casual sex in the last year (Chen et al. [@CR4]). A similar study conducted in Shenzhen found that 4% of surveyed migrants had taken part in commercial sex and only 36% of them reported consistent condom use (Sun et al. [@CR25]). An exaggerated vulnerability is experienced by individuals in dual-risk populations, such as migrants who are MSM. In a study of migration patterns among MSM, Guangdong had the highest migrant inflow ratios---migrant MSM were moving into Guangdong from areas of higher HIV prevalence among the broader MSM population (Mi et al. [@CR19]). A study conducted in Guangzhou showed that migrant MSM, compared to local MSM, have higher odds of reporting unprotected anal intercourse, having multiple male sexual partners, and lower rates of condom use (Wu et al. [@CR31]). ### Surveillance Among Migrant Workers {#Sec33} Because migrants were significantly over-represented among HIV case reports, six sentinel surveillance sites were set up in the Pearl River Delta region, where the migrant population is most concentrated, beginning in 2010. The annual HIV prevalence among migrants sampled at the six sites overall was 0.04%, 0.14%, 0.12%, 0.08%, 0.17%, 0.04%, 0.04%, and 0.17% in the years from 2010 to 2017, respectively. A cross-sectional study in Zhuhai found that 75% of PLWH were migrants (Li et al. [@CR15]). A similar study in Dongguan found that the proportion of migrants among PLWH rose from 52% in 2010 to 71% in 2015 (Li et al. [@CR14]). A study conducted in Zhongshan in 2010 estimated an HIV prevalence of 0.13% among the migrant population (Tan et al. [@CR27]). A cross-sectional study conducted in three medium-sized Guangdong cities with large floating populations found the prevalence of HIV and syphilis were 0.17% and 1.31%, respectively (Fu et al. [@CR7]). Conclusion {#Sec34} ========== With sudden and rapid trade liberalization and economic development as a backdrop, China's HIV epidemic has taken a somewhat unique course in Guangdong province. Although slow to get started, with only 500 cases identified cumulatively as of 2003, HIV prevalence increased rapidly, particularly among high-risk groups. Guangdong must redouble its efforts in prevention and expand testing, treatment, and care if it is to bring its HIV epidemic under control. Authors gratefully acknowledge Jennifer M. McGoogan, who provided input and assisted with editing. Tag Archives: lunar This Friday night and Saturday morning is the best time to see the best lunar eclipse ever!! Okay, slight exaggeration but this lunar eclipse is definitely the longest for 100 years! And it is visible almost everywhere in the world… except for Northern America. Considering they had the solar eclipse last year, I think they will survive. What is a Lunar Eclipse? As covered in a similar post earlier this year, a lunar eclipse occurs when the Moon passes behind the Earth and into its shadow. The Moon does not have its own light source; that big pizza pie in the sky is reflecting light from the Sun on to the Earth. So when the Sun, Earth, and Moon are all aligned, it means the Moon will pass into the shadow of the Earth. This also means a lunar eclipse only happens during a full moon. Waxing and Waning Moons occur due to the odd-angle the Moon sits relative to the Earth and the Sun. The great news is you don’t need any special equipment; no funky glasses or special telescopes. Just pull up a seat and gaze at the moon. Bring snacks as well because lunar eclipses can last a while, and this one is the longest. Experts (like NASA and the Sydney Observatory) advise the moon will be eclipsed for one hour and 43 minutes!! During this time, we have the greatest opportunity to witness a “Blood Moon”. Wait… What is a Blood Moon? Some cultures used to refer to a total lunar eclipse as a blood moon. When the direct sunlight is completely blocked, the only other light seen is refracted through Earth’s shadow. This light looks red because of the ‘Rayleigh scattering‘ – that’s the scattering of light by particles. Light, as we see it, is a spectrum of colours. When it is refracted (or split) through the atmosphere, we can see different colours. This is most noticeable with the blue sky and the different colours in sunsets due to dust particles in the air. For a lunar eclipse, the Sun’s light refracts around the edge of the Earth and hits the Moon. Blue and violet wavelengths scatter more than red and orange wavelengths, so the red is more like to reach the moon. Thus, it looks like the Moon is bleeding. When and Where Can I See the Blood Moon? The absolute best viewing points are from Western Asia, across the Middle East, and East Africa. If you are in Australia, Oceania, Europe, and the rest of Africa, you still have a good chance of a great site. North America and Greenland are out of luck this year. Australia Not the best timing for us but an early start shouldn’t kill me. If you are specifically after the Red, then make sure you are comfortable looking up around 4.30am AEST on Saturday morning. The total eclipse should occur between 5.30am and 6.30am, with the Moon setting around 6.55am. The Moon is going to be close to the horizon, so look to the West-South-West. Asia Those in Central Asia will probably have the best viewing of all. Look up from around 3.30pm and you might be able to catch the Mars Opposition at the same time. For those in India, you should aim for around 11:50pm local time on Friday night. Middle East The Middle East should be able to see the whole event in its entirety. That’s 103 minutes to make yourself comfortable. The eclipse should start around 10:24pm local time. Europe The days are pretty long in Europe right now. Follow your early dinner with an evening walk to the best vantage point by 8.45pm. With your warm Summer nights, you can probably stretch out on the grass and soak it all in. I’m a little jealous. Africa Eastern Africa will have the best viewing across the continent with other regions maybe missing the start. My contacts tell me the eclipse should be completely visible in Eastern Africa from 3.30pm to 5.15pm local time. South America Most of South America will only catch the tail-end of the eclipse, after sunset on Friday 27 July. However, don’t be too disappointed because your next big event is a total solar eclipse on 2 July 2019, with totality running through Chile and Argentina. Still, tonight’s event is a nice way to kick off the evening. Yes, I will most likely be dragging my tired sorry butt out of bed early in the morning to check it out. Due to my sleep deprivation during the last three weeks, I am giving no guarantees for photos. You’ll just have to wait and see.--- title: "R Notebook" output: html_notebook --- This is an [R Markdown](http://rmarkdown.rstudio.com) Notebook. When you execute code within the notebook, the results appear beneath the code. Try executing this chunk by clicking the Run button within the chunk or by placing your cursor inside it and pressing Ctrl+Shift+Enter. ```{r} plot(cars) ``` Add a new chunk by clicking the Insert Chunk button on the toolbar or by pressing Ctrl+Alt+I. When you save the notebook, an HTML file containing the code and output will be saved alongside it (click the Preview button or press Ctrl+Shift+K to preview the HTML file). The preview shows you a rendered HTML copy of the contents of the editor. Consequently, unlike Knit, Preview does not run any R code chunks. Instead, the output of the chunk when it was last run in the editor is displayed. Zeus, after having been the leader of the victory of the Olympic gods against the titans, became the supreme god and, sitting on his throne, he started to reign over the world when the God raised his arm unveiling his powerful lightning bolts. The other gods bowed down in a sign of respect. No, God had as much authority as Zeus. Only the goddess Hera, the wife of Zeus, was as esteemed as
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35306, 27, 187, 9486, 540, 1979, 28, 187, 9486, 22008, 5456, 3298, 28, 187, 187, 10971, 13 ]	’t stand up to research. A study of New York City schools found a positive relationship between principal experience and school performance, which was broadly defined to include not just test scores, but other measures such as student absences. Researchers suggested an important takeaway from their findings should be that “policies that lengthen principals’ careers will, on average, improve school performance.” Leading a school is a tremendously challenging job which requires a complex set of skills. Many of those skills cannot be taught in graduate school but must be mastered through years of trial and error. Experienced principals are better positioned to cultivate relationships that will lead to success, support teachers instructionally, and train the next generation of school administrators in how to lead effectively. Their compensation should recognize and reward the value that they bring to the job. One of the most troublesome outcomes of North Carolina’s principal pay plan is that it discourages principals from working in schools that need strong leadership the most. Research is clear that having an effective principal in place is especially crucial in schools that serve our most disadvantaged students. Our policies must encourage principals to want to work in those schools, or at the very least not deter them from doing so. Unfortunately, the new plan does just that. North Carolina’s principal pay rate is based on the last three years of growth data. If a principal who has been rated “exceeded growth” for three consecutive years moves into a low-performing school, he or she has two years to bring that school up to the “exceeded” level before seeing a reduction in salary. In schools that generally employ the least experienced teachers and have the highest rates of teacher turnover, that’s a very difficult proposition. When the new pay plan was implemented, some North Carolina principals faced reductions in salary of more than $20,000. The legislature’s response to concerns about this fact was to institute a “hold harmless” clause whereby principals who didn’t see enough standardized test growth would see their salaries frozen at the level of the previous year. The clause was renewed for the upcoming school year, but again frozen at 2016-17 levels, meaning principals whose students didn’t show enough growth will see a second straight year with no raise. That’s not an effective approach when it comes to attracting and retaining school leaders. Principals are second only to teachers among school-related factors in terms of impact on student learning. It’s essential that we treat them in ways that will lengthen their careers and encourage the best among them to work in schools where their talents are needed most. The General Assembly’s current approach to compensation does a grave disservice to our veteran principals and will further weaken North Carolina’s low-performing schools. It’s a model in need of a major overhaul. Justin Parmenter was named a finalist for Charlotte-Mecklenburg Schools teacher of the year in 2016. He currently serves as a Design Team member with Hope Street Group’s North Carolina Teacher Voice Network and sits on the Advisory Board of Red 4 Ed NC. He writes frequently about public education in North Carolina at http://notesfromthechalkboard.com/ where this article originally appeared.Q: User-Entered value for Array Size doesn't actually change the array's size. [Java] So as the title says, I'm trying to get a user inputted size to my array, yet every time I run the program it does not change the array size. I'm pretty sure its something to do with my constructors but i'm not positive. Any help would be appreciated! Class 1 (Numbers) package lab1; import java.util.Random; public class Numbers { public int size; public Integer[]arr = new Integer [size]; public Numbers () { for (int i = 0; i < size; i++){ arr[i] = new Integer(i); } } public Numbers(int size){ this.size = size; for (int i = 0; i < size; i++){ arr[i] = new Integer(i); } } public void generateNumbers(){ System.out.println(arr.length); Random rand = new Random(); for (int i = 0; i < arr.length; i++) { arr[i] = rand.nextInt(100); } } public int count(int val){ int count = 0; for (int i = 0; i < arr.length; i++){ if (arr[i] == val){ count++; } } return count; } public String toString() { StringBuilder builder = new StringBuilder(); for (int i = 0; i < arr.length; i++){ builder.append(arr[i]).append(" "); } return builder.toString(); } } Class 2 (Lab1) package lab1; import java.util.Scanner; public class Lab1 { public static void main(String[] args) { Numbers numbers = new Numbers(); @SuppressWarnings("resource") Scanner input = new Scanner(System.in); int menu = 1; while (menu != 0){ System.out.println("1 to create array of new size\n" + "2 to generate random numbers into array\n" + "3 to count a value\n" + "4 to display array\n" + "0 to quit\n"); menu = input.nextInt(); switch (menu) { case 1: System.out.println("Enter new size:\n"); int size = input.nextInt(); size = numbers.size; System.out.println("Array has been generated of size: " + numbers.size + "\n"); break; case 2: numbers.generateNumbers(); System.out.println("Numbers have been generated\n"); break; case 3: System.out.println("Enter number to search for:\n"); int num = input.nextInt(); System.out.println("There are " + numbers.count(num) + " of the number " + num); break; case 4: System.out.println(numbers.toString()); break; } } } } A: First problem: you're not changing the value of size in your instance of Numbers: size = numbers.size; This updates the local variable size, not the member variable of numbers, overwriting the value you just read from the scanner. To update the member variable with that value: numbers.size = size; Second problem: you're not actually changing the size of the array. The array is created when the instance of the class is initialized: public int size; public Integer[]arr = new Integer [size]; At the time it is created, size is zero, so arr is initialized to be a zero-length array. Changing the value of size won't change the size of arr automatically. You will need to create a new instance and assign it to the arr member variable. If you are specifying this at construction time: public Numbers(int size){ this.size = size; this.arr = new Integer[size]; for (int i = 0; i < size; i++){ arr[i] = new Integer(i); } } Note that because size == 0 initially, your default constructor (public Numbers()) does nothing: the body of the for loop for (int i = 0; i < size; i++){ is never executed, because i == 0 and size == 0 initially, so 0 < 0 is false. You should probably just remove the default constructor, so you always have to specify a value for size to construct the instance. If you remove the default constructor, you can remove the inline initialization of arr: public Integer[]arr; since a non-null value will be assigned in the constructor. Alternatively, if you only ever use Numbers in the code you've given, you can get rid of both constructors, and just declare your fields as: public int size = 0; public Integer[] arr = new Integer[0]; However, in your code, you are trying to change the length of the array after it has been constructed. In this case, you would need to create a new array whenever you change the value of size, for example: numbers.size = size; numbers.arr = Arrays.copyOf(numbers.arr, numbers.size); Arrays.copyOf will appropriately truncate your array or pad it with zeros, depending upon whether size is less than or greater than the current length of the array. Note that it would be usual to encapsulate such changes in a method on Numbers: public void setSize(int size) { this.size = size; this.arr = Arrays.copyOf(this.arr, size); } and make the fields private, so that they can only be updated by methods in Numbers: private int size; private Integer[]arr; Finally,
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2803, 326, 812, 4833, 3729, 13247, 7882, 15, 1292, 604, 3729, 9733, 7024, 327, 4135, 323, 253, 10713, 273, 697, 2739, 285, 7236, 13, 2139, 1057, 4135, 417, 21854, 10058, 3729, 9733, 323, 41185, 253, 3564, 326, 3997, 352, 32, 1623, 253, 10214, 13, 6944, 13554, 1408, 275, 253 ]	why each factor is insufficient, (c) then makes a blanket assertion that the district court abused its discretion because these factors combined with his employ- ment record, lack of criminal record for 70 years, and community ties, were not present to an exceptional degree to warrant departure. The majority’s analysis blatantly disregards the mandate of Koon and the amended Sentencing Guidelines. The United States Supreme Court in Koon ruled that "Congress allows district courts to depart from the applicable Guideline range if ‘the court finds that there exists an aggravating or mitigating circum- stance of a kind, or to a degree, not adequately taken into consider- ation by the Sentencing Commission.’" See Koon, 518 U.S. at 92 (citing 18 U.S.C. § 3553(b)). Several factors mentioned by the Sen- tencing Guidelines may combine to create mitigating or aggravating circumstances sufficient to warrant a basis for departure. See gener- ally Debeir, 186 F.3d at 573. Consistent with Koon, the district court properly found the combination of permissible factors placed the case outside of the heartland of cases contemplated by the Sentencing Guidelines. The district court examined a variety of factors and found Coble to be a 75-year-old man who had no criminal record, served as a combat pilot in two wars, employed as a commercial airline captain, had strong family ties, and whose sole offense was to attempt to use a bogus comptroller’s warrant to satisfy a tax lien against his prop- erty. The district judge stated that in his 17 years of sentencing, he did not think that there has been a federal court who sentenced anyone with Coble’s characteristics within the initial guideline range. (J.A. at 237.) In his institutional experience, Coble’s case was outside of the UNITED STATES v. COBLE 17 heartland of cases contemplated by the guidelines and some departure was warranted. The district judge’s considerable sentencing experi- ence and familiarity with other tax cases are crucial to understanding why the judge departed in this case. At sentencing, the district judge exercised considerable restraint and integrity in announcing his ruling. He acknowledged that he could exercise his discretion and grant an undeserved "acceptance of responsibility" three level departure from the applicable offense level and such a ruling would be almost "appeal proof." (J.A. at 237.) Instead, he considered his experience with tax cases and stated that, in 17 years, he had not seen anyone sentenced to a lengthy term of incarceration for this offense where the defendant had Coble’s unique personal characteristics. The district judge’s decision to depart two levels, a frugal two levels, embodied the traditional permissible exercise of discretion in sentencing. See Koon, 518 U.S. at 98. District courts have an institu- tional advantage and vantage point over appellate courts in comparing factors because district courts see so many more Sentencing Guide- line cases than do appellate courts. See Koon, 518 U.S. at 98 (acknowledging that in 1994 approximately 94% of Guidelines cases were not appealed); United States v. Hairston, 96 F.3d 102, 106 (4th Cir. 1996) (acknowledging the institutional advantage of district court in determining sentences). The district judge’s findings of fact con- cerning specific circumstances of a case are important because it per- mits the flexibility necessary for a defendant to be appropriately sentenced when his case involves unique and unusual facts. See Koon, 518 U.S. at 99. See, e.g., United States v. Reilly, 178 F.3d 1288 (4th Cir. 1999) (unpublished) (upholding district court’s eleven level departure on the grounds of post-offense rehabilitation after the dis- trict court made extensive factual findings). The majority sweeps aside Judge Bullock’s 17 years of institutional wisdom and casts a fleeting glance at Koon’s acknowledgment that Congress allows a dis- trict court to depart from the applicable Guideline range if the district court finds atypical mitigating circumstance not adequately taken into consideration by the Sentencing Commission. See Koon, 518 U.S. at 91. In sum, the majority makes a de novo determination that if it were in the district court’s position, it would have decided the case differ- ently. Under Koon, an appellate court should reverse a district court’s 18 UNITED STATES v. COBLE decision if the district court abuses its discretion, not if it disagrees with the district court’s decision. See, e.g., United States v. Goodman, 2001 WL 273143, *2-3 (4th Cir. 2001) (unpublished) (applying the standard in Koon and holding that, even though it was a very close case, the court cannot conclude that the district court abused its dis- cretion in departing downward). The majority’s decision comes with- out the benefit of the trial judge’s sentencing experience or impression of the testimony presented at Coble’s trial.3 The majority’s position is completely at odds with the mandate of Koon to review a downward departure from the Sentencing Guidelines for an abuse of discretion. The district court did not abuse its discretion in finding Coble’s case was atypical. The Sentencing Guidelines structure sentencing in a way that adds predictability to the sentencing process. In drafting these guidelines, the Sentencing Commission could not possibly con- template every type of circumstance conceivable in sentencing. There is still room for individualized consideration of the whole person within the framework of the Sentencing Guidelines. Coble is a recal- citrant tax evader, a 75-year-old man, who had no criminal record, served as a combat pilot in two wars, has strong family ties, and had a good employment record as a commercial airline captain. Coble was convicted because he attempted to use a bogus comptroller’s warrant to satisfy a tax lien. The population of offenders possessing Coble’s offense and other characteristics is small, and indeed, rare. The dis- trict judge could find no case which factually compared to Coble’s case in his 17 years experience, and decided to impose a frugal two level downward departure from the applicable Sentencing Guidelines which allowed him to place Coble in home electronic detention for six months and on probation for three years. I respectfully dissent because the district court did not abuse its discretion in this case and I would affirm the district court’s judgment. 3 This appeal follows a contested trial and sentencing hearing where the Government did not succeed at an attempt to link Coble to a group which is notorious for promoting tax evasion schemes. The Government could not prove that Coble was a member of the group or an adherent to the group’s wide ranging criminal activities. MANUFACTURED IN OUDENNARDE (FLANDERS) SILK AND WOOL WITH GOLD THREADS ADDED TO THE SURFACE MIDDLE OF THE 16TH CENTURY The two Flemish tapestries of the Bagatti Valsecchi Museum called Mercury and his Children and The Sun and his Children, might be the extant portion...Class Win and P2 Overall at Bathurst 12H Patrick Long, Marc Lieb, David Calvert-Jones and Matt Campbell scored a sensational class win and claimed p2 overall in a hectic, unforgettable Liqui-Moly Bathurst 12 Hours on Saturday, at the legendary Mount Panorama circuit. The #12A Ice Break Coffee Porsche 911 GT3 R, run by Competition Motorsports, ran a strong weekend throughout, progressing through the unique qualifying format to ultimately take place in the Top Ten shootout, where new Porsche Junior Matt Campbell qualified 9th overall. During the race, which saw a characteristic high number of safety car periods due to Mount Panorama’s incredibly narrow confines and large, varied grid, the Ice Break team led for a few stretches but was in and amongst the fight at the front all day. The team did incur three penalties in the race for various infractions, but were running first in class and P3 overall when pre-race favorite Shane Van Gisbergen spectacularly crashed out from P2 with just minutes remaining. 2016 FIA WEC Champion Marc Lieb said, “Second place and class victory feels pretty good. We had to cope with a lot of minor setbacks, probably more than any other team, and that alone makes this a super result.” Patrick remarked, “My stints were good. During the second stint I unfortunately nudged a Mercedes. I wanted to overtake it to snatch the lead but he didn’t budge an inch and I didn’t want to risk anything. So I decided to pull back and keep my position. But I was on the dirty side of the track and I couldn’t avoid touching the car. Luckily nothing more happened.”North Korea’s dependency on China for energy and food has long been cited as a source of Chinese political leverage and a primary factor that could influence North Korean stability. But if North Korea depends on China for the bulk of its food and fuel, why does China not punish tiny North Korea for biting the hands that feed it? On the contrary, underlying trends run in the
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8106, 15, 2594, 11726, 26333, 13, 5405, 273, 308, 8707, 13, 4458, 287, 42418, 5838, 13, 268, 15, 31118, 15, 187, 688, 253, 1246, 1083, 13, 352, 310, 15279, 281, 9186, 6827, 15, 399, 280, 2364, 434, 16038 ]	that an "altercation might arise." Mrs. Dickey directed the Balko's daughter "not to be upset and to avoid any confrontation with the Anthonys," and indicated that she "would attempt to reach the police." The police were called and the judge talked to them. Mrs. Dickey then asked the judge to advise her of the proper course to take in the event the Anthonys removed the children before the police arrived to inform them of the custody order. The judge responded that she should charge the parents with abduction in the Magistrate's Court. Later, that afternoon, Mrs. Dickey discovered that Mr. and Mrs. Anthony had in fact retrieved two of their three children. She thereupon signed a complaint against the Anthonys for child abduction. In pertinent part, that complaint recites that Mr. and Mrs. Anthony "did . . . unlawfully COMMIT THE ACT OF CHILD ABDUCTION to-wit: did then and there remove Dolores Anthony, age two years, and Maria Anthony, age four years, from legally appointed guardians without permission of court." On the basis of this complaint, an arrest warrant was issued by a Justice of the Peace. The Anthonys' complaint alleges, and Mrs. Dickey does not dispute, that pursuant to this warrant Mrs. Anthony was arrested by a Delaware state trooper, detained for four hours for interrogation and other police procedures and released after posting a $500 bail bond. 571 Mr. Anthony, according to the complaint, surrendered to the police voluntarily and, after undergoing interrogation and other procedures, was released on his own recognizance. At the request of the Division of Social Services, the charges against the Anthonys were subsequently dismissed pursuant to an order issued by the Family Court. In her affidavit, Mrs. Dickey states that her sole purpose in charging the Anthonys with abduction was "to seek return of the children before their expressed threat to leave the state had been carried out." She further states that it was never her intention "to punish, harass or persecute the Anthonys" and that she acted "with the sole intention of providing the Anthony children with the protection I felt they needed." The Anthonys were arrested for allegedly violating Section 624 of Title 11 of the Delaware Code, which provides as follows: Whoever, without the color of right, forcibly abducts, takes or conveys away any child under the age of 12 years, from the home or usual place of abode of such child, or from the custody and control of the parent or lawful guardian of such child; or Whoever, without the color of right, and against the consent of the parent or lawful guardian of such child, persuades or entices from the usual place of abode or house of such child, or from the custody and control of the parent or guardian of such child; or Whoever knowingly secretes or harbors such child, with the intent to deprive such parent or guardian, or any person who may be in lawful possession of such child, of the custody, care and control of such child Shall be fined not more than $500, or imprisoned not more than 10 years, or both. The Anthonys observe that the respective subsections of this statute require that the alleged abductors act either "without the color of right" or "knowingly." From this language they infer that a necessary element of the crime defined by Section 624 is knowledge on the part of the alleged abductors that they lack lawful custody over the children that they are accused of abducting. Mrs. Dickey, they claim, was fully aware that the Anthonys had not been apprised of the Family Court's custody order when they retrieved their children from the Balko household. Hence, they conclude, Mrs. Dickey lacked probable cause to suspect the Anthonys of child abduction when she secured the warrant for their arrest. Additionally, they maintain that Mrs. Dickey's conceded purpose of "seek(ing) the return of the children before their threat to leave the state had been carried out," while perhaps well-intentioned, was nevertheless an improper motive for securing an arrest warrant. Consideration of the Anthonys' argument must begin with the observation that Mrs. Dickey neither arrested the Anthonys herself nor made the formal determination that there was an adequate legal foundation for that arrest. Mrs. Anthony was arrested by a Delaware state trooper, while Mr. Anthony surrendered to the police voluntarily. The determination that probable cause existed to arrest the Anthonys was made by the magistrate who signed the warrant for their arrest. Mrs. Dickey's participation in these events was limited to appearing before that magistrate and averring facts concededly true and purportedly indicative of the Anthonys' criminal conduct.[3] Thus, she essentially acted as a complainant, whose affidavit to a judicial officer serves to trigger criminal proceedings. At common law, a complainant who initiates unfounded criminal proceedings is potentially liable only for the tort of malicious prosecution. Distinguishing actions for false arrest and imprisonment from actions for malicious 572 prosecution, Professor Prosser has written that: The distinction between the two lies in the existence of valid legal authority for the restraint imposed. If the defendant complies with the formal requirements of the law, as by swearing out a valid warrant, so that the arrest of the plaintiff is legally authorized, the court and its officers are not his agents to make the arrest, and their acts are those of the law and the state, and not to be imputed to him. He is, therefore, liable, if at all, only for a misuse of legal process to effect a valid arrest for an improper purpose. The action must be for malicious prosecution. Prosser, Law of Torts, p. 62. Since she complied with the proper legal formalities and played no role in the actual arrest and detention of the Anthonys, Mrs. Dickey's liability at common law, if any, must rest on a theory of malicious prosecution. The law of malicious prosecution likewise provides the controlling legal framework for determining her liability under Section 1983 as well. Conduct which gives rise to a cause of action for malicious prosecution may also constitute a violation of Section 1983 if that conduct is undertaken under color of state law and results in a deprivation of a federally secured right. See Nesmith v. Alford, 318 F.2d 110, 126 (5th Cir. 1963). In passing upon a claim brought under Section 1983, however, the Third Circuit has cautioned that "the § 1983 right of action should not be construed to be in derogation of the common law." Johnson v. Alldredge, 488 F.2d 820 (1973). Relying on this principle, that court has held, for example, that "officials immune from damage suits at common law would also be immune from such suits under Section 1983." Id. And, aside from the immunity from suit available to state officers acting within the scope of their official discretion, other defenses, likewise derived from the common law, are also available in Section 1983 suits. In Pierson v. Ray, 386 U.S. 547, 87 S.Ct. 1213, 18 L.Ed.2d 288 (1966), the Supreme Court reiterated that Section 1983 "should be read against the background of tort liability" and accordingly permitted police officers, sued under Section 1983 for committing an unconstitutional arrest, to invoke the defense of "good faith and probable cause" traditionally claimed by police officers in a common law action for false arrest. The Supreme Court's reliance on the common law in Pierson, as well as the similar approach of this circuit in Johnson, suggests that wherever common law tort doctrine would afford protection from liability, similar protection must be available in analogous actions brought under Section 1983. We turn, therefore, to the law of malicious prosecution to determine not only Mrs. Dickey's liability under state tort law but her liability under Section 1983 as well. Traditionally, liability for malicious prosecution will not be imposed if the defendant initiated criminal proceedings either with probable cause to believe that the plaintiff was guilty or for the primary purpose of bringing an offender to justice.[4] Prosser, *573 Law of Torts, § 113, p. 853; Restatement of the Law of Torts, § 653, p. 382; Nesmith v. Alford, 318 F.2d 110, 121 (5th Cir. 1963). Because either probable cause or a legitimate law enforcement objective will suffice to defeat an action for malicious prosecution, the standard for recovery in such actions is more stringent than in the kindred area of false arrest, where the defendant police officer must show both good faith and probable cause in order to prevail. See Pierson v. Ray, supra; Bivens v. Six Unknown Agents, 456 F.2d 1339, 1347-1348 (2nd Cir. 1972). As Professor Prosser has observed, a more rigorous standard of liability is appropriate in an action for malicious prosecution because the defendant "has proceeded under the proper legal formalities." Prosser, supra, p. 853. A complainant who swears out an arrest warrant before a magistrate entrusts that magistrate with the task of evaluating the legal sufficiency of the charges he has brought; assuming his motive is proper, the complainant should not be penalized for subsequently disclosed errors in legal judgment. Similarly, even if the complainant has acted in bad faith, the goal of "efficient enforcement of the criminal laws" requires that he be free from liability when he has commenced criminal proceedings in a reasonable and justifiable belief that the alleged wrongdoer is guilty. See Restatement, Law of Torts, Introductory Note, p. 380. In the present case, it is unnecessary to examine Mrs. Dickey's motivation
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6255, 9749, 15, 754, 434, 6523, 24794, 11678, 13, 24794, 3551, 562, 273, 253, 15229, 5534, 1601, 964, 964, 964, 390 ]	, and all that. She can see him stumbling to the house with his head down, breathing hard through his nose. Viva ze bool. "By then I knew I was in bed, but I could hear this low voice that didn't sound like mine at all, it sounded like some stranger's voice, and it couldn't put corners on any of the words it was saying. 'Ell-ee-itch-un, ell-ee itch-un,' that's what it sounded like. 'Ell-ee itch-un, Ish!'" Tell me which one. Tell me which one, Trish. Harvey falls silent, thinking. Considering. The dust motes dance around his face. The sun makes his T-shirt almost too dazzling to look at; it is a T-shirt from a laundry-detergent ad. "I lay there waiting for you to run in and see what was wrong," he finally says. "I lay there all over goosebumps, and trembling, telling myself it was just a dream, the way you do, of course, but also thinking how real it was. How marvelous, in a horrible way." He stops again, thinking how to say what comes next, unaware that his wife is no longer listening to him. Jax-that-was is now employing all her mind, all her considerable powers of thought, to make herself believe that what she is seeing is not blood but just the Volvo's undercoating where the paint has been scraped away. Undercoating is a word her subconscious has been more than eager to cast up. "It's amazing, isn't it, how deep imagination goes?" he says finally. "A dream like that is how a poet—one of the really great ones—must see his poem. Every detail so clear and so bright." He falls silent and the kitchen belongs to the sun and the dancing motes; outside, the world is on hold. Janet looks at the Volvo across the street; it seems to pulse in her eyes, thick as a brick. When the phone rings, she would scream if she could draw breath, cover her ears if she could lift her hands. She hears Harvey get up and cross to the nook as it rings again, and then a third time. It is a wrong number, she thinks. It has to be, because if you tell your dreams they don't come true. Harvey says, "Hello?" Rest Stop He supposed that at some point between Jacksonville and Sarasota he did a literary version of the old Clark-Kent-in-the-phone-booth routine, but he wasn't sure just where or how. Which suggested it wasn't very dramatic. So did it even matter? Sometimes he told himself the answer to that was no, the whole Rick Hardin/John Dykstra thing was nothing but an artificial construct, pure press agentry, no different from Archibald Bloggert (or whatever his real name might have been) performing as Cary Grant, or Evan Hunter (whose actual birth name had been Salvatore something-or-other) writing as Ed McBain. And those guys had been his inspiration . . . along with Donald E. Westlake, who wrote hard-boiled "caper" novels as Richard Stark, and K. C. Constantine, who was actually . . . well, no one really knew, did they? As was the case with the mysterious Mr. B. Traven, who had written Treasure of the Sierra Madre. No one really knew, and that was a large part of the fun. Name, name, what's in a name? Who, for instance, was he on his biweekly ride back to Sarasota? He was Hardin when he left the Pot o' Gold in Jax, for sure, no doubt. And Dykstra when he let himself into his canal-side house on Macintosh Road, certainly. But who was he on Route 75, as he flowed from one town to the other beneath the bright turnpike lights? Hardin? Dykstra? No one at all? Was there maybe a magic moment when the literary werewolf who earned the big bucks turned back into the inoffensive English professor whose specialty was twentieth-century American poets and novelists? And did it matter as long as he was right with God, the IRS, and the occasional football players who took one of his two survey courses? None of that mattered just south of Ocala. What did was that he had to piss like a racehorse, whoever he was. He'd gone two beers over his usual limit at the Pot o' Gold (maybe three) and had set the Jag's cruise control at sixty-five, not wanting to see any strobing red lights in his rearview mirror tonight. He might have paid for the Jag with books written under the Hardin name, but it was as John Andrew Dykstra that he lived the majority of his life, and that was the name the flashlight would shine on if he was asked for his operator's license. And Hardin might have drunk the beers in the Pot o' Gold, but if a Florida state trooper produced the dreaded Breathalyzer kit in its little blue plastic case, it was Dykstra's intoxicated molecules that would wind up inside the gadget's educated guts. And on a Thursday night in June, he would be easy pickings no matter who he was, because all the snowbirds had gone back to Michigan and he had I-75 pretty much to himself. Yet there was a fundamental problem with beer any undergraduate understood: You couldn't buy it, only rent it. Luckily, there was a rest stop just six or seven miles south of Ocala, and there he would make a little room. Meanwhile, though, who was he? Certainly he had come to Sarasota sixteen years before as John Dykstra, and it was under that name that he had taught English at the Sarasota branch of FSU since 1990. Then, in 1994, he'd decided to skip teaching summer classes and have a fling at writing a suspense novel instead. This had not been his idea. He had an agent in New York, not one of the superstuds, but an honest enough guy with a reasonable track record, who had been able to sell four of his new client's short stories (under the Dykstra name) to various literary magazines that paid in the low hundreds. The agent's name was Jack Golden, and while he had nothing but praise for the stories, he dismissed the resulting checks as "grocery money." It had been Jack who'd pointed out that all John Dykstra's published stories had "a high narrative line" (which was agentese for a plot, as far as Johnny could tell) and suggested his new client might be able to make $40,000 or $50,000 a whack writing suspense novels of a hundred thousand words. "You could do that in a summer if you found a hook to hang your hat on and then stuck to it," he'd told Dykstra in a letter. (They hadn't progressed to using the phone and the fax at that point.) "And it would be twice as much as you'd make teaching classes in the June and August sessions down there at Mangrove U. If you're going to try it, my friend, now is the time—before you find yourself with a wife and two-point-five children." There had been no potential wife on the horizon (nor was there now), but Dykstra had taken Jack's point; rolling the dice did not get easier as one grew older. And a wife and kids weren't the only responsibilities one took on as time slipped quietly by. There was always the lure of the credit cards, for instance. Credit cards put barnacles on your hull and slowed you down. Credit cards were agents of the norm and worked in favor of the sure thing. When the summer-teaching contract came in January of '94, he had returned it unsigned to the department head with a brief explanatory note: I thought this summer I'd try to write a novel instead. Eddie Wasserman's reply had been friendly but firm: That's fine, Johnny, but I can't guarantee the position will be there next summer. The man in the chair always gets right of first refusal. Dykstra had considered this, but only briefly; by then he had an idea. Better still, he had a character: The Dog, literary father of Jaguars and houses on Macintosh Road, was waiting to be born, and God bless the Dog's homicidal heart. • • • Ahead of him was the white arrow on the blue sign twinkling in his headlights, and the ramp curving off to the left, and the high-intensity arc-sodium lights illuminating the pavement so brightly that the ramp looked like part of a stage set. He put on his blinker, slowed to forty, and left the interstate. Halfway up, the ramp branched: trucks and Winnebagos to the right, folks in Jaguars straight ahead. Fifty yards beyond the split was the rest stop, a low building of beige cinder block that also looked like a stage set under the brilliant lights. What would it be in a movie? A missile-command center, maybe? Sure, why not. A missile-command center way out in the boonies, and the guy in charge is suffering from some sort of carefully concealed (but progressive) mental illness. He's seeing Russians everywhere, Russians coming out of the damn woodwork . . . or
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745, 14, 10565, 985, 49599, 10, 187, 6573, 12296, 5239, 7470, 323, 897, 275, 12296, 14, 13670, 38121, 403, 2530, 15, 496, 8956, 342, 253, 3688, 13, 247, 873, 273, 3295, 275, 661, 323, 897, 275, 19736, 2718, 403, 2530, 285, 26115, 281, 2085, 5520, 8342, 2929, 285, 2714, 3420, 3045, 1223, 11850, 1175, 11993, 5319, 15, 380, 275, 661, 285, 12296, 5239, 273, 253, 1246, 3688, 10738, 7126, 3295, 3045, 285, 1708, 7957, 1255, 2439, 247, 2491, 273, 3420, 13, 10237, 611, 16, 58, 43662, 5052, 327, 8342, 2929, 387, 3809, 3379, 18819, 13, 347, 973, 347, 7126, 3379, 1430, 285, 13367, 15, 5488, 13, 253, 12296, 873, 13276, 1175, 13367, 275, 271, 3126, 1907, 247, 4942, 1029, 4719, 273, 14842, 27427, 6083, 15, 831, 13367, 13276, 253, 897, 273, 26611, 43662, 1453, 6297, 15, 380, 275, 661, 285, 12296, 5239, 273, 253, 1246, 3688, 671, 789, 9696, 973, 275, 247, 13506, 9538, 390, 7954, 1369, 833, 313, 70, 15, 72, 904, 3488, 42240, 1351, 22441, 10, 390, 247, 9538, 1417, 313, 4786, 312, 1417, 10, 985, 15, 187, 7673, 5742, 13, 247, 2173, 18722, 873, 323, 830, 8287, 8862, 13, 4231, 20891, 13, 285, 28422, 275, 661, 310, 10557, 13, 247, 8862, 18722, 11616, 247, 7802, 273, 3527, 8862, 3495, 313, 8506, 1508, 10, 285, 1480, 8862, 13718, 313, 32201, 14783, 582, 247, 28422, 18722, 11616, 247, 7802, 273, 3527, 4797, 898, 313, 2925, 26, 10, 285, 247, 28422, 18722, 8508, 1907, 253, 7212, 27, 187, 7096, 19, 89, 1438, 89, 3953, 9, 8683, 20, 41, 10, 19, 15, 24, 187, 18675, 49, 68, 7096, 19, 89, 1438, 89, 3953, 9, 8683, 19, 17659, 19, 10, 17, 15, 22, 187, 7096, 19, 89, 1438, 89, 3953, 9, 8683, 19, 17659, 9, 36, 19, 41, 21, 20492, 10, 17, 15, 25, 187, 2811, 249, 367, 68, 6125, 247, 268, 18563, 6711, 21222, 13787, 313, 284, 10557, 275, 11754, 11683, 1621, 15, 25069, 8688, 16, 2251, 24257, 13, 253, 9410, 273, 534, 403, 11217, 11249, 407, 3806, 558, 285, 247, 4231, 20891, 18722, 11616, 247, 4231, 20891, 18722, 8508, 1907, 7212, 27, 209, 187, 2811, 249, 1165, 310, 247, 27201, 15, 187, 510, 3688, 2529, 11249, 310, 6828, 281, 247, 2173, 12296, 873, 323, 11993, 12296, 14, 13670, 3888, 970, 21917, 2130, 12296, 14, 13670, 38121, 13, 824, 347, 20955, 44, 43, 2025, 9, 35152, 2769, 35152, 10, 38121, 13, 285, 625, 3782, 13, 745, 14, 10565, 12296, 14, 13670, 38121, 13, 824, 347, 253, 20955, 44, 43, 2025, 374, 1518, 9, 35152, 10, 19736, 13, 18461, 407, 44990, 17655, 14, 28794, 472, 6487, 273, 5226, 80, 46317, 13, 34280, 15, 380, 12296, 873, 13276, 271, 12296, 14, 13670, 3295, 19736, 281, 4711, 1029, 3290, 3295, 3888, 1907, 7126, 3295, 3045, 285, 1708, 7957, 1255, 327, 247, 2491, 273, 3420, 13, 3782, 327, 8342, 2929, 15, 5488, 13, 253, 12296, 873, 13276, 1175, 13367, 13, 824, 347, 12296, 7882, 13, 285, 1086, 522, 285, 7355, 313, 70, 15, 72, 15, 23396, 272, 10, 275, 247, 5235, 273, 12620, 15, 187, 510, 1246, 8862, 13, 4231, 20891, 13, 285, 28422, 17515, 12296, 16672, 1016, 19142, 275, 2087, 432, 670, 470, 15, 1762, 281, 670, 1384, 22923, 2462, 273, 387, 1878, 581, 18722, 285, 247, 4958, 11616, 253, 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14842, 27427, 6083, 672, 841, 767, 4753, 313, 74, 15, 70, 904, 3295, 386, 285, 14842, 27427, 5570, 10, 403, 26115, 275, 253, 1072, 12296, 285, 943, 3464, 19663, 672, 26115, 342, 247, 14842, 27427, 5570, 15, 496, 643, 3000, 253, 36348, 943, 452, 4209, 35051, 275, 253, 12296, 4958, 594, 326, 597, 651, 417, 830, 25824, 2308, 273, 14842, 17255, 407, 253, 14842, 27427, 6083, 390, 949, 4884, 342, 643, 4295, 275, 253, 12296, 15, 9157, 13, 253, 36348, 943, 417, 8071, 342, 253, 14842, 262, 386, 281, 830, 25824, 2308, 273, 7006, 326, 588, 13, 2057, 4745, 390, 689, 673, 13, 5926, 562, 273, 2900, 15, 1198, 1650, 253, 36348, 943, 417, 830, 47261, 12872, 390, 26793, 326, 452, 247, 14955, 281, 830, 29111, 326, 452, 6137, 35051, 275, 253, 12296, 4958, 689, 673, 275, 824, 2308, 347, 281, 19323, 342, 253, 6799, 3045, 273, 253, 11993, 985, 15, 187, 510, 4236, 3295, 1103, 1364, 671, 10738, 1175, 1708, 7957, 1255, 327, 247, 4618, 2491, 273, 3420, 13, 3782, 13, 2714, 2929, 15, 733, 310, 671, 1774, 326, 253, 3295, 1103, 4711, 4122, 5937, 1420, 11462, 3888, 1907, 253, 4569, 43192, 13, 3340, 327, 8342, 2929, 15, 187, 1147, 369, 1119, 326, 1142, 273, 253, 36348, 326, 10048, 253, 806, 767, 6095, 13, 10775, 13, 1175, 35051, 285, 1708, 7957, 1255, 13, 4197, 11462, 3888, 326, 313, 18, 10, 1474, 4215, 432, 253, 7445, 43192, 6907, 8571, 327, 8342, 2929, 13, 285, 16, 263, 313, 19, 10, 574, 1698, 5937, 66, 327, 8342, 2929, 15, 187, 510, 18722, 873, 273, 253, 1246, 3688, 13, 3400, 1175, 3295, 18814, 307, 327, 8342, 2929, 28, 1175, 1708, 7957, 1255, 28, 5520, 611, 16, 58, 43662, 13, 1175, 8487, 7882, 13, 285, 1175, 11993, 3045, 15, 380, 12296, 873, 273, 253, 1246, 3688, 12093, 27, 187, 66, 8862, 12296, 11616, 247, 7802, 273, 3527, 8862, 3495, 313, 8506, 1508, 10, 285, 1480, 8862, 13718, 313, 32201, 14783, 558, 187, 66, 28422, 12296, 11616, 247, 7802, 273, 3527, 4797, 898, 313, 2925, 26, 10, 285, 247, 28422, 18722, 8508, 1907, 253, 7212, 27, 187, 7096, 19, 89, 1438, 89, 3953, 9, 8683, 20, 41, 10, 19, 15, 24, 187, 18675, 49, 68, 7096, 19, 89, 1438, 89, 3953, 9, 8683, 19, 17659, 19, 10, 17, 15, 22, 187, 7096, 19, 89, 1438, 89, 3953, 9, 8683, 19, 17659, 9, 36, 19, 41, 21, 8575, 10, 17, 15, 25, 187, 7096, 19, 89, 1438, 89, 3245, 2811, 249, 367, 68, 6125, 247, 268, 18563, 6711, 21222, 13787, 28, 285, 187, 66, 4231, 20891, 12296, 11616, 247, 4231, 20891, 18722, 1907, 253, 7212, 27, 209, 187, 7096, 19, 89, 1438, 89, 3245, 2811, 249, 1165, 310, 247, 27201, 15, 496, 247, 9013, 14704, 13, 1165, 310, 10939, 4236, 253, 1387, 273, 49424, 11253, 273, 33322, 13, 18528, 33322, 13, 11914, 13, 27747, 13, 23160, 13, 285, 14864, 3358, 4040, 312, 2163, 1514, 7235, 15, 187, 510, 275, 661, 273, 253, 1246, 3688, 19142, 432, 670, 470, 15, 1762, 281, 670, 1384, 6, 18722, 28, 13027, 13, 432, 670, 470, 15, 18, 281, 670, 854, 10543, 285, 625, 13027, 13, 432, 670, 470, 15, 22, 281, 670, 608, 10543, 407, 2801, 13, 1754, 327, 253, 2264, 2801, 273, 253, 12296, 13, 1754, 327, 253, 11914, 830, 273, 253, 36348, 15, 733, 943, 320, 7192, 326, 253, 4588, 7043, 830, 273, 253, 18722, 908, 275, 253, 12296, 778, 320, 1027, 313, 70, 15, 72, 904, 253, 18722, 778, 320, 275, 253, 308, 3788, 830, 481, 380, 36348, 778, 320, 275, 616, 7043, 830, 13, 824, 347, 271, 42391, 5148, 313, 15061, 13, 611, 13, 390, 8182, 10, 390, 40163, 552, 33322, 15, 3808, 273, 841, 7043, 4948, 13, 824, 347, 6897, 13, 403, 21917, 2130, 15, 5131, 7043, 4948, 476, 320, 1160, 970, 973, 1929, 5609, 15, 187, 688, 581, 14704, 13, 253, 275, 661, 273, 253, 1246, 3688, 19142, 27, 387, 1878, 581, 8862, 12296, 1907, 247, 7985, 1708, 32593, 273, 432, 670, 470, 15, 22232, 281, 670, 470, 15, 38447, 387, 247, 24082, 11747, 991, 273, 432, 21566, 281, 35771, 285, 387, 247, 337, 27, 22, 13, 933, 23458, 275, 1824, 28, 387, 1878, 581, 28422, 12296, 1907, 247, 7985, 1708, 32593, 273, 432, 670, 470, 15, 2904, 281, 670, 337, 15, 2417, 387, 247, 24082, 11747, 991, 273, 432, 50059, 281, 721, 1237, 285, 387, 247, 337, 27, 22, 13, 933, 23458, 275, 1824, 28, 387, 1878, 581, 4231, 20891, 12296, 1907, 247, 7985, 1708, 32593, 273, 432, 670, 470, 15, 9992, 281, 670, 470, 15, 28950, 387, 247, 24082, 11747, 991, 273, 432, 36725, 281, 28564, 285, 387, 247, 337 ]	is to provide a first ink composition comprising a first colorant, and a second ink composition comprising a second colorant and a precipitating agent (e.g., inorganic salts), which will react with the first colorant in the first ink composition so that upon contact of the first ink and the second ink on the printing medium a precipitate is formed, thus preventing color bleed between the first ink composition and the second ink composition. Likewise, many inks used commercially represent a compromise in an attempt to achieve an ink evidencing at least an adequate response in each of the aforementioned characteristics. For example, a number of inks and ink sets suffer from black to color bleed which make their use less desirable or impossible for a number of color-intensive printing applications. Likewise, many of the known inks and ink sets suffer from poor lightfastness and humid hue shift/bleed on special media. Other problems are encountered when attempting to use these known inks and ink sets in reservoir based off-axis printing systems. In view of the foregoing, there exists a need in the industry for inks that work well in both fiber and foam based off-axis systems as well as in pens/cartridges without any fiber or foam material, and for ink formulations which have improved properties and which do not improve one property at the expense of the others, such as image quality, light fastness, architecture, performance and reliability. More specifically, there exists a need for improved black-to-yellow (K/Y) bleed for faster plain paper printing, no humid hue shift/bleed for magenta inks on special media, good plain paper chroma and lightfastness, and/or compatibility of inks with new reservoir material in an ink supply (e.g., as seen in off-axis system cartridges) Color ink sets suitable for use in ink-jet printers are provided. In accordance with the invention, a set of color inks for use in printer systems are provided and formulated to provide improved plain paper and special media performance while maintaining good printing characteristics. The inks and ink sets of the present invention exhibit excellent color performance and lightfastness across a range of media, robust K/Y bleed resistance on plain paper at fast print speeds, as well as excellent printability and reliability. Furthermore, the ink set enables good reliability in an environment having a relatively high concentration of precipitating agents. This reliability enables the use of precipitation bleed control mechanisms. The inks and ink sets of the present invention also work equally well in a synthetic fiber or foambased (e.g., polyurethane foam) or a fiberless (foamless) system. More specifically, a specific dye set for formulating yellow, magenta, and cyan inks is disclosed, a yellow dye comprising a mixture of acid yellow 23 (AY23) and direct yellow 132 (DY132), a cyan dye comprising a mixture of acid blue 9 (AB9) and a cyan dye compound having the formula: xe2x80x94(SO3H)2.7 CuPcxe2x80x94(SO2NH2)0.5 xe2x80x94(SO2NH(C2H4 OH)0.8 wherein Pc represents a phthalocyanine nucleus (as disclosed in Patent Application No. WO 99/67334, the contents of which are incorporated herein by reference); and a magenta dye comprising a magenta dye compound having formula: wherein Q is a cation. The invention described herein is directed to a specific ink set for printing ink-jet images using commercially available ink-jet printers, such as DESKJET(copyright)(copyright) printers, and more particularly, off-axis ink-jet printers, such as the DESKJET 2200(copyright) printer, manufactured by Hewlett-Packard Company of Palo Alto, Calif. The ink set enables an ink-jet color printer to produce high quality color images having excellent color performance and lightfastness on a range of media, particularly on plain paper. Furthermore, the ink set enables good reliability, such as ink stability, and decap and recovery (e.g. crusting) in a variety of environments. The present yellow, magenta, and cyan aqueous ink compositions each comprise in general from about 0.05 to about 20 wt % of at least one dye and a vehicle comprising the following components (in wt % of total ink composition): from about 5 to about 30 wt % of at least one organic solvent; 0 to about 5 wt % of at least one component independently selected from the group consisting of surfactants, buffers, precipitating agents and biocides. All concentrations herein are in weight percent of total ink composition, unless otherwise indicated. The purity of all components is that employed in normal commercial practice for ink-jet inks. In the practice of the invention, each ink color, namely, yellow, magenta, and cyan can comprise more than one dye load. That is, there can be one or more ink-jet ink supplies filled for each ink color, each supply having a different dye load or a different dye. As used herein, the term xe2x80x9cinkxe2x80x9d refers to the inks of the present invention. In selecting the colorants for the ink set of the present invention, the following factors were considered: reduced or absence of humid hue shift; good color performance, particularly, on plain paper; good lightfastness; good black to color bleed resistance; excellent printability and readability; and compatibility of inks with reservoir fiber-based materials in the ink supply. Of particular importance in the present invention was the selection of appropriate colorants capable of providing the aforementioned characteristics in a reservoir-based off-axis printer, as well as providing those attributes in a printer or pen lacking such a fiber material. In order to achieve the above-mentioned goals, the dyes or colorants selected for the present ink set should exhibit good compatibility (e.g., stable in the ink vehicle) in various environments. For example, the selected colorants should exhibit little, if any, significant reactivity with precipitating agents when these two materials (i.e., colorant and precipitating agent) are formulated in the same ink and should remain soluble when formulated with a precipitating agent. In other words the dyes should have sufficient solubility in the ink vehicle so that they would not form unwanted levels of precipitate by the precipitating agents or through reaction with other components in the ink. Additionally, the dyes should not react with the precipitant to form unwanted levels of compounds that will, either immediately or over time, drop out of solution. For example the dyes should not form insoluble complexes or salts that have a tendency to form aggregates that have decreased solubility in the ink vehicle over time in such levels as to interfere with the desired performance of the printing system. The selected colorants must also exhibit good lightfastness on a wide range of media, particularly, special paper. It is also important that the colorants produce highly chromatic printed images having the appropriate hue, especially on plain paper. It was found that many of the dyes that satisfied the first two requirements, namely, good solubility and lightfastness, produced printed images that (1) deviated from the ideal hue angle targets on plain paper, and/or (2) had low chroma on plain paper. The dye set of the present invention, provides good color gamut on plain paper; good lightfastness; improved K/Y bleed, good pH stability, and good printing performance. The ink set of the present invention comprises: a yellow ink comprising a mixture of acid yellow 23 (AY23) and direct yellow 132 (DY132); a cyan ink comprising a mixture of acid blue 9 (AB9) and a cyan dye compound having the formula: xe2x80x94(SO3H)2.7 CuPcxe2x80x94(SO2NH2)0.5 xe2x80x94(SO2NH(C2H4OH)0.8 xe2x80x83wherein Pc represents a phthalocyanine nucleus; and a magenta ink comprising a magenta dye having the formula: xe2x80x83wherein Q is a cation. In a preferred embodiment, Q is independently selected the group of cations consisting of ammonium, substituted ammonium, sodium, lithium, potassium, and tetramethylammonium ion. The inks of the present invention comprise from about 0.05 to about 20% dye; preferably, from about 0.1 to about 8%; and more preferably, from about 0.5 to about 5%; by weight, based on the total weight of the ink, based on the sodium form of the dyes. It should be understood that the actual salt form of the dye used in the ink may be different (e.g., the dye may be in the TMA form). The dyes may be in their salt form, such as an alkali metal (Na, K, or Li) or quaternary ammonium. Some of these salt forms, such as Na, are commercially available. Other salt forms can be made using well known techniques. In one embodiment, the inks of the present invention comprise: at least one yellow ink having a visible light absorbance of from about 0.242 to about 0.620 at a lambdamax of from 404 to 412 and at a 1:5,000 dilution in water; at least one cyan ink having a visible light absorbance of from about 0.08 to about 1.55 at a lambdamax of from 624 to 632 and at a 1:5,000 dilution in water; at least one magenta ink having a visible light absorbance of from about 0.020 to about 0.807 at a lambdamax of from 540 to 550 and at a 1
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776, 16529, 3417, 1895, 187, 187, 5064, 24677, 1549, 26221, 1552, 310, 12832, 9825, 9741, 264, 275, 10566, 2167, 15, 1422, 452, 281, 4086, 690, 1846, 4394, 562, 1735, 673, 285, 2770, 327, 8928, 7794, 15, 1605, 254, 285, 9741, 264, 1361, 441, 4677, 1691, 352, 457, 84, 417, 13438, 13, 533, 253, 1551, 403, 3965, 19437, 15 ]	backgroundColor = "#008000"; } } </script> Michel Lemieux Michel Lemieux (born February 13, 1959 in Indianapolis, Indiana) is a Canadian multimedia artist from Quebec, whose career has incorporated work in theatrical design, installation art, film, video, dance and music. First coming to prominence in the early 1980s as a performance artist whose work explored the integration of new media technologies into experimental pop music in a manner similar to Peter Gabriel and Laurie Anderson, more recently he has concentrated primarily on creating, designing, directing and producing multimedia theatrical presentations for events, theatrical companies and other artists. Career A 1979 graduate of the National Theatre School of Canada, Lemieux composed music for dance and theatrical troupes including La La La Human Steps, and did performance art work in Montreal before breaking through to wider success with his 1984 show Solide Salade. The show, a complex performance piece which incorporated film and video projections, music, dance and visual and lighting design, had a successful sold-out run in Montreal before touring venues across North America, Europe and Japan. In 1986, Lemieux performed the show at Expo 86, and signed to the record label Audiogram, with whom he released a self-titled album of songs from Solide Salade. He won the CASBY Award for Most Promising Male Vocalist, was nominated for the Juno Award for Most Promising Male Vocalist at the Juno Awards of 1986, and garnered two Prix Félix nominations for Best English-Language Pop/Rock Album and Best Video ("Romantic Complications"). In 1988, he premiered his new show Mutations at the arts festival of the 1988 Winter Olympics in Calgary, Alberta, and released the album Taming the Power Inside. He toured Mutations across Canada, and at World Expo 88 in Australia. Taming the Power Inside was again a Félix nominee for Best English Pop/Rock Album. In 1990, he premiered his first works co-created with Victor Pilon instead of as a solo artist; Pilon has since been Lemieux's creative and business partner in most of his subsequent work. Their first works together were Lemieux's new performance piece Free Fall, and Le Souffle de Pythagore, a holographic video dance work which was Lemieux's first work created for another performer. In 1991, Lemieux and Pilon created In Mid Air, a theatrical piece about the then-imminent transfer of Hong Kong from British to Chinese control which was created for Hong Kong's Festival 2000. In 1992, Lemieux and Pilon created Têtes Chercheuses, a commissioned performance piece for the 25th anniversary of Montreal's Saidye Bronfman Centre, and created and designed concert performances for UZEB and Michel Rivard, while Lemieux collaborated with Richard Blackburn on the design and staging of the parade to kick off Montreal's 350th anniversary celebrations. Lemieux and Pilon have since collaborated on works including Grand Hôtel des Étrangers, the stage design and direction of the Prix Félix ceremony in 1995, theatrical adaptations of Jean Cocteau's Orféo, William Shakespeare's The Tempest and Luc Plamondon's Starmania, and Cirque du Soleil's 2006 show Delirium. Lemieux was named an Officer of the Order of Canada in 2012, and a Chévalier of the National Order of Quebec in 2014. Lemieux is openly gay. He has stated that while his work addresses universal themes rather than gay-specific ones, he does consider his sexuality to influence his creative perspective. Works As performer Le Tympan de la Cantatrice (1982) L'Oeil rechargeable/The Rechargeable Eye (1983) Solide salade (1984) Mutations (1988) Free Fall / Voix de passage (1990) As creator or director Le Souffle de Pythagore (1990) In Mid Air (1991) Têtes Chercheuses (1992) Act of Faith / Feux sacrés (1993) Grand Hôtel des Étrangers (1994) Territoire Intérieur / À mille lieux (1994) Hommage à la musique du Cirque du Soleil (1995) Reach for the Stars / La route des étoiles (1995) Pôles (1996) Time Travel / Voyage dans le temps (1997) Orféo (1998) Harmony 2000 (1999) Ocean of Hope / Océan d’espoir (1999) Translucide (2000) This is a Sphere (2000) Anima (2002) The Planets (2003) Soleil de minuit (2004) La Tempête (2005) Delirium (2006) NORMAN (2007) Starmania Opéra (2008) La Belle et la Bête (2011) Continuum - Planetarium Rio Tinto and Espace pour la vie (2013) Dreamscapes (2014) ICARUS (2014) Cité Mémoire (2016) Discography Michel Lemieux (1986)Taming the Power Inside'' (1987) References External links Category:Living people Category:1959 births Category:People from Indianapolis Category:Canadian multimedia artists Category:Canadian installation artists Category:Canadian video artists Category:Canadian theatre directors Category:Canadian theatre managers and producers Category:Canadian performance artists Category:Canadian production designers Category:Canadian experimental musicians Category:Canadian electronic musicians Category:Canadian composers Category:Canadian male composers Category:Canadian male singers Category:Artists from Montreal Category:LGBT artists from Canada Category:LGBT musicians from Canada Category:LGBT directors Category:Officers of the Order of Canada Category:Knights of the National Order of Quebec Category:Gay artists Category:Gay musicians Category:National Theatre School of Canada alumni Category:Musicians from MontrealQ: Handling array value in JS I have a problem with my arrays in JavaScript. I can't seem to get the value correctly. I create my array in PHP like this: $data = Array(); $get = mysql_query("SELECT x,y,sid FROM table WHERE uid='1'"); while($row = mysql_fetch_assoc($get)){ $data[$row['x']] = Array(); $data[$row['x']][$row['y']] = $row['sid']; } $data = json_encode($row) EDIT The json_encode comes out as "false" /EDIT I then assigned this $data to a JS variable as sdata. So then i try to get the value in JS but its not working. I get an undefined error. This is my Javascript: var i = 1; var j = 5; if(sdata["x"] == i && sdata["y"] == j){ alert(sdata["x"]["y"]["sid"]); } Its meant to alert me the value of "sid" but i get: Undefined Any ideas where my mistake is? A: Given your json alert(sdata["x"]["y"]["sid"]); should be alert(sdata["sid"]); as the json encoded data you show is only a one dimensional array EDIT If your json comes out as false, that's a different story: $data = json_encode($row); Should be inside your loop, for good practice, and if you're just encoding the $row why even bother with $data[$row['x']] = Array(); $data[$row['x']][$row['y']] = $row['sid']; Otherwise try print_r($row); within your while statement and make sure your expected result is coming through from mysql in the first place. EDIT If you are trying to get the $data variable in json then use $data = json_encode($data); outside of your loop. EDIT JSFiddle to return sid for given x and y - I'm sure it can be done in a cleaner way, but it's a start http://jsfiddle.net/HWByj/ var sdata = {"4":{"4":"1"},"7":{"1":"0"}}; var i = 4; var j = 4; if(typeof sdata[i] != 'undefined') { if(typeof sdata[i][j] != 'undefined') { alert(sdata[i][j]); //gives you the value of sid } } I'll give hints I guess>Snorunt for the climate (also looks like Moomin, popular in my particular area)>Aggron for the iron mines everywhere>Lampent for a popular urban legend>Lycanroc for the wolves starting to repopulate the state>Bergmite for the stupidly cold weather>Shellder for our invasive species problem >>38560398This is literally anywhere forested in NA though. You have to rule some common ones out next time and focus on cultural aspects. Deer and forested help us figure put it’s not desert, but the rest are pretty useless.
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185. 186. 187. 188. 189. 190. 191. 192. 193. 194. 195. 196. 197. 198. 199. 200. 201. 202. 203. 204. 205. 206. 207. 208. 209. 210. 211. 212. 213. 214. 215. 216. 217. 218. 219. 220. 221. 222. 223. 224. 225. 226. 227. 228. 229. 230. 231. 232. 233. 234. 235. 236. 237. 238. 239. 240. 241. 242. 243. 244. 245. 246. 247. 248. 249. 250. 251. 252. 253. 254. 255. 256. 257. 258. 259. 260. 261. 262. 263. 264. 265. 266. 267. 268. 269. 270. 271. 272. 273. 274. 275. 276. 277. 278. 279. 280. 281. 282. 283. 284. 285. 286. 287. 288. 289. 290. 291. 292. 293. 294. 295. 296. 297. 298. 299. 300. 301. 302. 303. 304. 305. 306. 307. 308. 309. 310. 311. 312. 313. 314. 315. 316. 317. 318. 319. 320. 321. 322. 323. 324. 325. 326. 327. 328. 329. 330. 331. 332. 333. 334. 335. 336. 337. 338. 339. 340. 341. 342. 343. 344. 345. 346. 347. 348. 349. 350. 351. 352. 353. 354. 355. 356. 357. 358. 359. 360. 361. 362. 363. 364. 365. 366. 367. 368. 369. 370. 371. 372. 373. 374. 375. 376. 377. 378. 379. 380. 381. 382. 383. 384. 385. 386. 387. 388. 389. 390. 391. 392. 393. 394. 395. 396. 397. 398. 399. 400. 401. 402. 403. 404. 405. 406. 407. 408. 409. 410. 411. 412. 413. 414. 415. 416. 417. 418. 419. 420. 421. 422. 423. 424. 425. 426. 427. 428. 429. 430. 431. 432. 433. 434. 435. 436. 437. 438. 439. 440. 441. 442. 443. 444. 445. 446. 447. 448. 449. 450. 451. 452. 453. 454. 455. 456. 457. 458. 459. 460. 461. 462. 463. 464. 465. 466. 467. 468. 469. 470. 471. 472. 473. 474. 475. 476. 477. 478. 479. 480. 481. 482. 483. 484. 485. 486. 487. 488. 489. 490. 491. 492. 493. 494. 495. 496. 497. 498. 499. 500. 501. 502. 503. 504. 505. 506. 507. 508. 509. 510. 511.
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16670, 2201, 3910, 275, 20272, 32108, 15, 187, 187, 20167, 2048, 273, 322, 1848, 7282, 18, 68, 13, 401, 1719, 13, 285, 322, 3717, 18, 2692, 326, 5541, 8258, 369, 417, 12059, 275, 253, 2923, 7944, 15, 20272, 1341, 3890, 1698, 14, 20425, 30823, 285, 1077 ]	-AVV- and chemerin-156-AAV-injected mice. HCC progresses from hyperplastic nodules to adenomas to carcinomas \[[@B22-ijms-21-00252],[@B23-ijms-21-00252]\]. At the time of chemerin-156 overexpression, mice had already developed preneoplastic lesions \[[@B22-ijms-21-00252],[@B23-ijms-21-00252]\]. Larger tumors originate from these hyperplastic nodules. Chemerin-156 had no effect on tumor progression. The number of large tumors and the degree of tumor malignancy did not differ between the two groups of animals. Cancer-associated fibroblasts within the HCC environment contribute to disease progression. These cells express α-SMA, which is associated with poor survival of patients with HCC \[[@B48-ijms-21-00252]\]. In the tumors, α-SMA was comparably induced in both groups of mice in accordance with similar malignancy of liver tumors. The HCC biomarker AFP similarly increased during disease progression in all of the mice, further illustrating comparable tumor growth. Small tumors and neoplastic lesions usually do not secrete AFP and do not affect its serum level \[[@B28-ijms-21-00252]\]. The mechanisms by which chemerin may prevent formation of liver lesions remains unknown. Liver fibrosis and bioactive lipids like ceramides contribute to the pathogenesis of liver tumors \[[@B1-ijms-21-00252],[@B44-ijms-21-00252]\]. Based on histological, gene expression, and lipidomic data, chemerin-156 did not improve liver function. Cancer is associated with adipose tissue loss, but fat pad weights were not changed by chemerin overexpression. Of note, there was a negative correlation of liver to body weight ratio and intraabdominal fat pad weights. Fat atrophy appears to be triggered by the tumor and may supply cancers with fatty acids to generate ATP \[[@B49-ijms-21-00252]\]. Overexpression of chemerin in the liver did not alter adipose tissue mass and appears not to interfere with energy supply. Chemically-induced liver tumorigenesis is a stepwise process with distinct stages of initiation, promotion, and progression \[[@B50-ijms-21-00252]\]. The current model indicates that chemerin-156 retards initiation and/or early tumor growth. The expression of three genes, DOCK8, LHPP, and CYP1A2, was induced in the normal liver tissues of chemerin-156-AVV compared to control-AAV infected mice. The suppression of these genes in the murine tumors and human HCC \[[@B41-ijms-21-00252],[@B42-ijms-21-00252],[@B43-ijms-21-00252]\] suggests a role in hepatocarcinogenesis. Future experiments have to evaluate a potential anti-tumor capacity of these proteins. Again, equal expression of these genes in the HCC of both animal groups showed that chemerin-156 had little or no protective role in the progression of HCC. Principally, this seems to contradict recent studies demonstrating the anti-cancer effects of this chemerin isoform in xenograft models \[[@B15-ijms-21-00252],[@B16-ijms-21-00252]\]. Compared to DEN-induced HCC, xenograft models do not develop liver fibrosis \[[@B51-ijms-21-00252]\]. Proteinases like chymase were induced in the fibrotic liver and may contribute to chemerin inactivation \[[@B52-ijms-21-00252],[@B53-ijms-21-00252]\]. Chromosomal aberrations, inter- and intra-tumor heterogeneity are prevalent in carcinogen-induced hepatocarcinogenesis \[[@B51-ijms-21-00252]\] and affect cell function. The heterogeneous sensitivity of HCC cells to drugs like sorafenib has been documented \[[@B54-ijms-21-00252]\] and the responsiveness of different HCCs to chemerin-156 may vary. Furthermore, CMKLR1 was strongly downregulated in the HCC tissues of the mice studied herein, and this may further abolish the protective effects of chemerin-156. However, CMKLR1 levels were maintained in the tumors of mice 21 weeks after DEN injection \[[@B47-ijms-21-00252]\], consistent with the ability of chemerin-156 to exert beneficial activities in early carcinogenesis. Chemerin expression was analyzed in different human cancers, whereas levels of CMKLR1 were hardly investigated. The human protein atlas provides information about CMKLR1 in colorectal, breast, prostate, lung, and thyroid cancer \[[@B55-ijms-21-00252]\]. CMKLR1 protein was not prognostic in these different tumor diseases \[[@B55-ijms-21-00252]\]. In the liver, CMKLR1 is expressed by hepatocytes, Kupffer cells, bile-duct cells, and hepatic stellate cells \[[@B56-ijms-21-00252]\]. Preliminary data from our group suggest that CMKLR1 protein was reduced in non-viral human HCC \[[@B57-ijms-21-00252]\]. Until now, the factors regulating CMKLR1 in liver cells have hardly been described. Adiponectin and IL-6 seem to induce CMKLR1 mRNA in hepatocytes. In hepatitis C infection, hepatic CMKLR1 was normal, levels were reduced or induced in NASH \[[@B5-ijms-21-00252]\]. Further research has to analyze CMKLR1 expression in HCC as well as chronic liver diseases. The contribution of serum chemerin to HCC is a further unresolved question. Patients with liver cirrhosis are at risk of developing HCC \[[@B58-ijms-21-00252]\]. Low systemic chemerin was associated with mortality in patients with decompensated disease \[[@B59-ijms-21-00252]\]. On the other hand, serum chemerin was comparable in non-cancer patients, patients with colorectal liver metastases, and HCC \[[@B60-ijms-21-00252]\]. Most chemerin in serum is inactive \[[@B61-ijms-21-00252]\], and detailed analysis of chemerin isoforms in patients with cirrhosis and HCC may help to resolve this issue. Full-length chemerin overexpression in adrenocortical carcinoma cells promoted β-catenin degradation, which was initiated by phosphorylation of the protein at S33, S37, or T41. Moreover, it inhibited the phosphorylation of p38 kinase \[[@B8-ijms-21-00252]\]. Subsequently, cell proliferation, invasion, and tumorigenesis were blocked. Interestingly, exogenously-provided active chemerin-157 had no effect on these features \[[@B8-ijms-21-00252]\]. Aberrant activation of the Wnt/β-catenin pathway was reported in liver cancer, but nuclear localization of β-catenin was not detected in the DEN model \[[@B60-ijms-21-00252]\]. Mice with hepatocytes unable to secrete Wnts had comparable tumor burden and HCC histology as the respective controls \[[@B62-ijms-21-00252]\]. These studies showed that β-catenin was dispensable during DEN-induced HCC \[[@B62-ijms-21-00252],[@B63-ijms-21-00252]\]. Indeed, protein levels of β-catenin were essentially identical in tumorous and non-tumorous tissues, and did not vary between the groups. Moreover, p38 protein and its phosphorylated form were not changed in tumors of DEN-injected mice \[[@B39-ijms-21-00252]\]. Accordingly, p38 mRNA was not upregulated in the tumors nor by chemerin-156 overexpression. Akt was activated by chemerin in short-term exposure. Treatment with chemerin for a longer time caused a decline in the levels of phosphorylated Akt. Of note, after 4 h incubation, Akt activation reverted to the resting levels \[[@B16-ijms-21-00252]\]. There was no evidence to suggest that Akt was activated by chemerin-156 in the cancer tissues analyzed. This kinase affects various signaling pathways and nearly identical gene expression in tumor and paratumor tissues of chemerin-156-AAV- and control-AAV-infected mice argues against differential activity of Akt. This may also apply to additional proteins, including the tumor suppressors p53 and PTEN. These pathways may contribute to the reduced number of small tumors in chemerin-156-overexpressing mice which is a subject of further investigations. The Fabp5 protein in HCC is associated with worse outcome and in vitro analysis revealed higher migration, invasion, and proliferation rates of cells with high Fabp5 protein levels \[[@B64-ijms-21-00252]\]. Identical expression of Fabp5 protein in the tumors of both groups again indicated comparable malignancies. Pnpla5 is a neutral lipid triacylglycerol lipase and, furthermore, has acylglycerol transacylase activity \[[@B45-ijms-21-00252]\]. Pnpla5 mRNA was highly expressed in HCC tissues of chemerin-156-infected mice. Triglyceride and diacylglycerol species were nevertheless equally abundant in the tumors of both groups. This indicates that Pnpla5 is not a primary determinant of hepatic triglyceride and diacylglycerol levels. However, it is also possible that Pnpla5 protein and enzymatic activity were not induced in parallel to mRNA levels. It would be interesting to clarify the role of this enzyme in hepatic lipid metabolism. Elevated diacylglycerol concentrations contribute to HCC proliferation \[[@B65-ijms-21-00252]\] and identical levels in the tumors of both animal groups further exclude major differences in HCC malignancy. Normal expression of SREBP1c, FAS, and SCD1 showed that lipogenesis was not altered in the cancer tissues. HCC cells express low-density lipoprotein and very
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595, 275, 2151, 434, 44244, 942, 187, 187, 34, 371, 26548, 14, 45721, 8524, 1253, 9, 52, 26796, 775, 3833, 504, 390, 7043, 4587, 5760, 253, 1824, 3268, 273, 253, 2133, 1253, 601, 1158, 273, 352, 323, 30297, 13 ]	the same woman who thinks calling Haiti a "shithole" is racist.” It IS racist characterizing people from “shithole” brown countries as not being as worthy of immigration as the nice white nations like Norway. Try to be at least a little bit honest, but I know that’s asking too much of you. We all know what he meant. I sometimes wonder what drives you people. Xenophobia and bigotry trump (pun intended) any Christian teaching you’ve had and you easily put it on the back burner. You rationalize it, you deny it, you even revel in it like dogs rolling in shit. The smell of the comments sections are smelling particularly foul the last few days. The people from there may or may not be good individuals but that is besides the point. They have no right to immigrate here and at a time when industries are becoming increasingly automatized we do not need illiterate unskilled people. You want them here because they will vote Dem (either legally or illegally). Outside of that, they can rot in ghettos for all you care. But that such people apparently sincerely believe that les deplorables grant them any moral credibility, let alone moral authority, is one of the most fascinating studies in human delusions of the age. This phenomenon may just be a particular instance of what Haidt noted: that conservatives understand liberals but liberals don't understand conservatives, so whatever liberals are banging on about to conservatives is very often going to be off-kilter enough to end up in "wtf?" territory. Lately, though, the moral grandstanding seems to me to be developing into a form of sociopathy, rather than being a basic philosophical misunderstanding or workaday lack of self-insight. I don't understand why people who do not support the President, expect him to do for them. When HW Bush reneged on his promise of no new taxes, he not only turned his supporters against him but also turned himself into a wussy. If Trump reneges on immigration, he'll be both toast and a wussy. You read it here first.Q: Hg ACL for cloning Is it possible to use the mercurial ACL extension to prevent specific users from cloning a repository? If so, how do you do it? A: You don't need the ACL extension to prevent specific users from cloning. The allow_read and deny_read settings in the [web] section of a hgrc file grant/remove clone rights. Cloning is really just hg init ; hg pull under the covers. http://www.selenic.com/mercurial/hgrc.5.html#web Our magazine always stood against all kinds of unfair and idiotic practices around us. The provocation for this write-up is the results of International Caricature Competition organized by Indian institute of Cartoonists. Unfortunately, we happened to see those prize winning entries. It was a clear case of ‘murder’ of the caricature art form ! Undoubtedly, Rtd. Judge Mr. Venkatachalayya, artist Andani and cartoonist Keshav were responsible for this tragedy. What more can we expect when these three caricature illiterate persons become the judges ! A review of these prize winning works would turn their heads down. Section- Manmohan Singh First prize: Except for its detailed work, this one is not at all a perfect caricature.The nose is unnecessarily distorted so big. Why Gandhi specs? [ Is it Gandhism ? ha ha ha.. ] His bushy eyebrows are missing. Second prize : Mr Manmohan Singhmight fall flatif he happened to see this one ! What is the ‘hole’ thing between forehead and turban ? Third prize : Here Mr Singh was butchered beyond recognition ! All those 3 consolation entries are realistic portraits ! Section - Sonia Gandhi First,second and third prize winning entries should have beenkept out of the competition itself for it’s realistic approach.All 3 are neat portraits! These 3 consolation winning works are not perfect ones. Now, what is a caricature after all ?A portrait ? No way ! Or is it just an exaggeration face of a person ? Exaggeration of face is okay to some extent. A perfect caricaturist would show thedistorted face as well as something about the person. But judges here simply ignored all this . It’s a big humiliation for those who believed in caricaturing. IIC did a lot of valuable programmes so far. But now it lost it’s respect with this blunder. Poor R V Deshapande, President of Congress has donated Rs3,50,000 as the prize money. Sadly, the money was spent to hire realistic artists to murder this Followers VAARE KORE-visitors PRAKASH SHETTY About Me Here is a rare species called Prakash Shetty. Born on April Fools Day,1960.I was addicted to cartooning at the age of fifteen [ 1975 ] I started my funny career with a kannada magazine called Santhosha. Then switched on to a English daily - The Times Of Deccan. Later with Mungaru daily and finally served The Week. At present Iam seriously into funny business. Spot caricaturing at events..drawing huge cartoon murals... staff caricatures on 40ft wall...t-shirt cartoons...coloured family caricatures...recently Prakash Shetty PUNCH became instant hit on ETV. My last misadventure was VAARE KORE,a humour magazine in kannada language.Fun Gallery is my new baby. Call 9591979629 0r 080-28606030 email id- [email protected]<ActionBar title="Extras & Events Demo"></ActionBar> <ScrollView> <StackLayout> <StackLayout android:visibility="collapsed"> <label text="Here auto-paging is enabled with an interval of 3 seconds." textWrap="true" margin="10,5,0,5" ></label> <label text="You can capture the tap and change events." textWrap="true" margin="10,5,0,5"></label> <label text="Page-indicator can be turned on/off and its color changed" textWrap="true" margin="10,5,20,5" ></label> </StackLayout> <StackLayout ios:visibility="collapsed"> <label text="You can capture the change events." textWrap="true" margin="10,5,0,5"></label> <label text="Page-indicator can have different animations and change color" textWrap="true" margin="10,5,20,5" ></label> </StackLayout> <GridLayout height="350"> <ns:Carousel #advCarousel height="100%" width="100%" color="white" (pageChanged)="pageChangedEvent($event)" indicatorColor="#fff" indicatorColorUnselected="#50ffffff" ios:autoPagingInterval="3" android:indicatorAnimation="swap" > <ns:CarouselItem *ngFor="let item of items" verticalAlignment="middle" [backgroundColor]="item.color" (tap)="pageTappedEvent($event)" > <GridLayout> <image [src]="item.image" stretch="aspectFill"></image> <label [text]="item.title" horizontalAlignment="center" backgroundColor="#50000000" height="30"></label> </GridLayout> </ns:CarouselItem> </ns:Carousel> </GridLayout> <label text="Indicator animation type: 'swap'" textWrap="true" ios:visibility="collapsed" margin="10,0,0,0"></label> <button text="Toggle indicator" (tap)="toggleIndicator()" margin="10,10,0,10" android:visibility="collapsed" ></button> <button text="Toggle indicator color" (tap)="toggleColor()" margin="10,10,0,10"></button> <label [text]=" 'Selected page: ' + currentPage" textWrap="true" margin="10,0,0,0"></label> <label [text]=" 'Tapped page: ' + tappedPage" textWrap="true" margin="0,0,0,0"></label> </StackLayout> </ScrollView> Pisces-Ferrum Phos– (Iron Phosphate) early inflammation–fever, start of throat and ear swelling and pain. Can stop hemorrhage, nosebleed. Use liberally in children's ailments Aquarius-Nat Mur–(Sodium Chloride or salt)- controls the water distribution of the body–so think of it for edema,
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39916, 432, 619, 10329, 15, 309 ]	) => { body.client = {type: 'WEB', id: 'RMV', name: 'webapp'} body.ext = 'RMV.1' body.ver = '1.18' body.auth = {type: 'AID', aid: 'x0k4ZR33ICN9CWmj'} return body } const hvvProfile = { locale: 'de-DE', timezone: 'Europe/Berlin', endpoint: 'https://www.rmv.de/auskunft/bin/jp/mgate.exe', transformReqBody, products, trip: true, radar: true, refreshJourney: true, reachableFrom: true } module.exports = hvvProfile Rules of the Game: Earnings Road Race It's another big week for earnings, with a little over half of the S&P 500 companies having delivered results thus far. Analysts are eyeing an overall year-over-year decline of 0.04% for the companies remaining. Of course, companies often set low expectations, so they will have a beat when reporting time rolls around. After Monday's bell, the beleaguered Herbalife (HLF) will deliver first-quarter results. Despite the fascination swirling around the company and the "he said, he said" battle between big activist investors, I'm just not interested. The stock continues to struggle, and even an earnings beat won't be enough to convince me of its viability at this time. While the chattering class will undoubtedly be preoccupied with Herbalife, I'll be watching some S&P names that report after the close. Hertz (HTZ) is one of our holdings. The stock has been delivering growth-style price appreciation since November. It's rallied above its 10-week average since then, rising to a new peak of $24.31 on Friday. Hertz is just on the verge of driving into large-cap land. Rival Avis (CAR) is also trading in new high ground. It has a market capitalization of nearly $9.7 billion. It has excellent liquidity, moving about 7.9 million shares per day, on average. This stock, however, has a high beta of1.80. Trade has been orderly as Hertz rallied to new highs in recent months, but a glance at the chart shows some erratic trading patterns in the not-so-distant past.This type of action is maddening for traders. But for investors with a longer time horizon, it's often wise to sit through some corrections, and even view pullbacks as opportunities to add shares. When Hertz reports after Monday's bell, analysts expect per-share income of $0.17 on revenue of $2.39 billion. Those would be increases over the year-ago quarter. Hertz beat views in each of the past four quarters. Looking at the current price, many investors would probably conclude that a pullback is due soon. Perhaps, but take a glance at the price-to-earnings ratio of 17, which suggests that this stock is not yet in "priced for perfection" mode, and appears to have some driving room ahead. Hertz closed Friday at $24.19a share. Also reporting after Monday's close is S&P 500 component Jacobs Engineering (JEC). Jacobs provides design, engineering and architectural services to corporate and government clients. This is also a mid-cap, with a market capitalization of $6.7 billion. It trades about 1 million shares per day, and has a beta of 1.46. This chart, too, indicates some wide-and-loose trading patterns that undoubtedly vex many traders. Jacobs has been in a correction since retreating from its March 28 high of $56.53. While momentum traders certainly would avoid this stock based on the technicals, the fundamentals merit a look. Analysts expect the company to report earnings per share of $0.83 on revenue of $2.93 billion, year-over-year increases on the top and bottom lines. The stock regained its 50-day line last week, and closed Friday at $51.65, 0.3%, above that key price line. For the year, analysts expect earnings of $3.33 per share, a gain of 13% over 2012. Consensus estimates were recently lowered, but the stock nonetheless appears to have good potential, based on the fundamentals.var R = require('../../../../dist/rambda.js'); var eq = require('./shared/eq'); describe('lastIndexOf', function() { var input = [1, 2, 3, 4, 5, 1]; var list = ['a', 1, 'a']; list[-2] = 'a'; // Throw a wrench in the gears by assigning a non-valid array index as object property. it('has R.equals semantics', function() { function Just(x) { this.value = x; } Just.prototype.equals = function(x) { return x instanceof Just && R.equals(x.value, this.value); }; eq(R.lastIndexOf(0, [-0]), -1); eq(R.lastIndexOf(-0, [0]), -1); eq(R.lastIndexOf(NaN, [NaN]), 0); eq(R.lastIndexOf(new Just([42]), [new Just([42])]), 0); }); it('dispatches to `lastIndexOf` method', function() { function Empty() {} Empty.prototype.lastIndexOf = R.always(-1); function List(head, tail) { this.head = head; this.tail = tail; } List.prototype.lastIndexOf = function(x) { var idx = this.tail.lastIndexOf(x); return idx >= 0 ? 1 + idx : this.head === x ? 0 : -1; }; var list = new List('b', new List('a', new List('n', new List('a', new List('n', new List('a', new Empty() ) ) ) ) ) ); eq(R.lastIndexOf('a', 'banana'), 5); eq(R.lastIndexOf('x', 'banana'), -1); eq(R.lastIndexOf('a', list), 5); eq(R.lastIndexOf('x', list), -1); }); it('finds function, compared by identity', function() { var f = function() {}; var g = function() {}; var list = [g, f, g, f]; eq(R.lastIndexOf(f, list), 3); }); });Most Helpful Positive Review Dec 02, 2009 It was a really good starter recipe. I added a bit to the ingrients, pickling salt, and changed the cooking method a bit.....I added a few spices like dill and basil, for just a little extra and added all sorts of different peppers esp hotter ones like chili peppers to give it a bit of color and extra kick since the vinegar and cooking will take away the heat of the peppers. BTW, if you don't like the heat of the peppers, you can add a little oil to the bottom of the jars before filling and it will help to take away some of the kick of the peppers! I also put some pickling salt in the vinegar/water before boiling, just a TBSP or so. Takes away a bit of the sour taste some might get. I also filled the jars differently, making it a lot easier and a lot less dangerous in my opinion. Instead of actually cooking the peppers, onions, garlic, and spices with the Vinegar/Water; I stuff them into clean jars and poured the really hot vinegar/water mixture over them. I then re-cooked the jar with lids on to make them seal, like the recipe. This allowed the peppers to cook in the jars through the boiling process, but not lose as much heat and crunch. It was also a little easier in my opinion, allowing me to stuff my jar completely with the cool, just cut ingredients, instead of having to ladle and stuff hot peppers into the jars, making sure they were filled and not burning myself in the process. Hope that helps and thanks for the great idea! Whew! I made these with a bunch of jalapenos and 2 cayenne peppers. I did throw in some evoo and fresh herbs as suggested by another reviewer. I also threw in some cherry tomatoes and green onions after I removed the pan from the heat -- I think you could pickle alomost anything in this mixture. I had some of the mixture left that wouldn't fit in the jars, so I added some more peppers for a few minutes, added 1/4 c. sugar and 1 T. salt, tossed it in the blender, and made some kickin' hot sauce. Simple recipe and pretty in the jars, too. A very simple and easy recipe. I use it to pickle banana peppers from my garden. I
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16, 16455, 4305, 16, 16455, 15, 4305, 16, 23290, 16, 1731, 1229, 1228, 187, 11, 1214, 248, 567, 4229, 21626, 6525, 39638, 318, 20942, 275, 5216, 2470, 1374, 880, 3614, 1358, 7280, 15, 681, 16, 16455, 4305, 16, 16455, 15, 4305, 16, 23290, 16, 1731, 1630, 1228, 187, 11, 1214, 78, 2131, 531, 408 ]	com/videojs/video.js/pull/2427)) * @misteroneill restore videojs.formatTime ([view](https://github.com/videojs/video.js/pull/2420)) * @misteroneill include child components with `true` in options ([view](https://github.com/videojs/video.js/pull/2424)) * @misteroneill create video.novtt.js in dist builds ([view](https://github.com/videojs/video.js/pull/2447)) * @misteroneill pass vtt.js option to tech ([view](https://github.com/videojs/video.js/pull/2448)) * @forbesjo updated the sauce labs config and browser versions ([view](https://github.com/videojs/video.js/pull/2450)) * @mmcc made sure controls respect muted attribute ([view](https://github.com/videojs/video.js/pull/2408)) * @dmlap switched global options back to an object at videojs.options ([view](https://github.com/videojs/video.js/pull/2461)) * @ogun fixed a typo in the Turkish translation ([view](https://github.com/videojs/video.js/pull/2460)) * @gkatsev fixed text track errors on dispose and in cross-browser testing ([view](https://github.com/videojs/video.js/pull/2466)) * @mmcc added type=button to button components ([view](https://github.com/videojs/video.js/pull/2471)) * @mmcc Fixed IE by using setAttribute to set 'type' property ([view](https://github.com/videojs/video.js/pull/2487)) * @misternoneill fixed vertical slider issues ([view](https://github.com/videojs/video.js/pull/2469)) * @gkatsev moved default and player dimensions to style els at the top of HEAD ([view](https://github.com/videojs/video.js/pull/2482)) * @gkatsev moved default and player dimensions to style els at the top of HEAD el ([view](https://github.com/videojs/video.js/pull/2482)) * @gkatsev removed non-default track auto-disabling ([view](https://github.com/videojs/video.js/pull/2475)) * @gkatsev exported event helpers on videojs object ([view](https://github.com/videojs/video.js/pull/2491)) * @nickygerritsen fixed texttrack handling in IE10 ([view](https://github.com/videojs/video.js/pull/2481)) * @gkatsev deep clone el for iOS to preserve tracks ([view](https://github.com/videojs/video.js/pull/2494)) * @forbesjo switched automated testing to BrowserStack ([view](https://github.com/videojs/video.js/pull/2492)) * @gkatsev fixed nativeControlsForTouch handling. Defaults to native controls on iphone and native android browsers. ([view](https://github.com/videojs/video.js/pull/2499)) * @heff fixed cross-platform track tests by switching to a fake tech ([view](https://github.com/videojs/video.js/pull/2496)) * @gkatsev improved tech controls listener handling. ([view](https://github.com/videojs/video.js/pull/2511)) * @dmlap move seek on replay into the flash tech ([view](https://github.com/videojs/video.js/pull/2527)) * @dmlap @gkatsev improve Flash tech error property and add an error setter to the base tech ([view](https://github.com/videojs/video.js/pull/2517)) * @dmlap update to videojs-swf 5.0.0-rc1 ([view](https://github.com/videojs/video.js/pull/2528)) * @dmlap expose start and end buffered times ([view](https://github.com/videojs/video.js/pull/2501)) * @heff fixed a number of console errors after testing ([view](https://github.com/videojs/video.js/pull/2513)) * @gkatsev made the sass files available via npm in src/css ([view](https://github.com/videojs/video.js/pull/2546)) * @heff removed playerOptions from plugin options because it created an inconsistency in plugin inits ([view](https://github.com/videojs/video.js/pull/2532)) * @heff added a default data attribute to fix the progress handle display in IE8 ([view](https://github.com/videojs/video.js/pull/2547)) * @heff added back the default cdn url for the swf ([view](https://github.com/videojs/video.js/pull/2533)) * @gkatsev fixed the default state of userActive ([view](https://github.com/videojs/video.js/pull/2557)) * @heff fixed event bubbling in IE8 ([view](https://github.com/videojs/video.js/pull/2563)) * @heff cleaned up internal duration handling ([view](https://github.com/videojs/video.js/pull/2552)) * @heff fixed the UI for live streams ([view](https://github.com/videojs/video.js/pull/2557)) * @gkatsev updated opacity of caption settings background color ([view](https://github.com/videojs/video.js/pull/2573)) * @gkatsev made all sass variables !default ([view](https://github.com/videojs/video.js/pull/2574)) * @heff fixed the inline volume control and made it the default ([view](https://github.com/videojs/video.js/pull/2553)) * @forbesjo fixed webkit deprecation warnings ([view](https://github.com/videojs/video.js/pull/2558)) * @forbesjo added Android and iOS browser testing ([view](https://github.com/videojs/video.js/pull/2538)) * @heff improved css selector strengths ([view](https://github.com/videojs/video.js/pull/2583)) * @heff moved scss vars to be private ([view](https://github.com/videojs/video.js/pull/2584)) * @heff added a fancy loading spinner ([view](https://github.com/videojs/video.js/pull/2582)) * @gkatsev added a mouse-hover time display to the progress bar ([view](https://github.com/videojs/video.js/pull/2569)) * @heff added an attributes argument to createEl() ([view](https://github.com/videojs/video.js/pull/2589)) * @heff made tech related functions private in the player ([view](https://github.com/videojs/video.js/pull/2590)) * @heff removed the loadedalldata event ([view](https://github.com/videojs/video.js/pull/2591)) * @dmlap switched to using raynos/xhr for requests ([view](https://github.com/videojs/video.js/pull/2594)) * @heff Fixed double loadstart and ready events ([view](https://github.com/videojs/video.js/pull/2605)) * @gkatsev fixed potential double default style elements ([view](https://github.com/videojs/video.js/pull/2619)) * @imbcmdth extended createTimeRange to support multiple timeranges ([view](https://github.com/videojs/video.js/pull/2604)) * @misteroneill rename "extends" to "extend" for ie8 ([view](https://github.com/videojs/video.js/pull/2624)) * @forbesjo removed the PhantomJS dependency ([view](https://github.com/videojs/video.js/pull/2622)) * @misteroneill re-exposed videojs.TextTrack ([view](https://github.com/videojs/video.js/pull/2625)) * @heff removed a second copy of video.novtt.js from dist ([view](https://github.com/videojs/video.js/pull/2630)) * @heff fixed timeranges deprecation warnings in tests ([view](https://github.com/videojs/video.js/pull/2627)) * @misteroneill
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73, 10, 426, 428, 1010, 4148, 11, 73, 428, 20504, 15, 1737, 403, 253, 4335, 2616, 273, 269, 1490, 19, 6177, 187, 19, 13, 495, 13, 2145, 13, 655, 187 ]	/(-162) - 6/9. 3, 19 List the prime factors of (-1 + -3)-1(57 + -34). 2, 23 Suppose -2z - 27 = 5. Let b = 34 - z. What are the prime factors of b? 2, 5 Suppose -101s = -107s - 204. Suppose -2p - p = 5o - 243, 3o - 173 = 5p. Let f = o + s. List the prime factors of f. 17 Let k(t) = t + 3. Let c be k(-7). Let m be (c/6)/((-2)/(-75)). Let l = 16 - m. What are the prime factors of l? 41 List the prime factors of 13/((-65)/(-2))2295. 2, 229 Let v(x) = x2 - 7x + 9. Suppose 3k = 7k - 5r - 9, -2r - 24 = -5k. Let j be v(k). Suppose -i = -ji + 12. What are the prime factors of i? 2, 3 Let n be (13 + -11)(-8)/2. Let z be (-27)/12 - 2/n. List the prime factors of z + -2 + 3 + 11. 2, 5 List the prime factors of 70908/30 - 15/25. 17, 139 Let d(b) = -3b + 10. Let f = 22 + -36. What are the prime factors of d(f)? 2, 13 Let s be 2 - 8 - (-3)/1. What are the prime factors of (356/8)/(s/(-6))? 89 Let x be ((-64)/6)/((-8)/12). Let n be (-3 + 7)4/x. What are the prime factors of n163/6? 2 Let u(m) = 3m*3 + 8m*2 + 2m - 1. Let p(q) = q*2 - 1. Let w(l) = 4p(l) - u(l). List the prime factors of w(-4). 7, 19 Let z(p) = p2 + p - 32. Let q be z(-7). Let j(b) = b3 - 4b2 + 4b + 1. Let l be j(3). Let t = q - l. What are the prime factors of t? 2, 3 Suppose 3j - 44 = -y, 2y = -4j - 6 + 64. Let v = 17 - j. Suppose 5u - 60 = vu. List the prime factors of u. 2, 5 Let o be ((-96)/(-14))/((-4)/(-42)). Suppose 0 = -p - 2p - o. What are the prime factors of (-4)/(((-3)/p)/(-1))? 2 What are the prime factors of -2(-1 - 1) + 1 + 2694? 2699 Let r(k) = 18k + 49. List the prime factors of r(38). 733 Suppose 9 = 6s + 3s. Let t(c) = 54c2 - 2c + 3. List the prime factors of t(s). 5, 11 List the prime factors of (1510/30)/((-1)/(-1 - 20)). 7, 151 Let w = -630 + 428. List the prime factors of (2/(-4))/(1/w). 101 Let m(t) = t + 1. Let d be m(-2). Let g(q) = q*2 + 7q + 17. Let s be g(-4). Let r = s - d. What are the prime factors of r? 2, 3 Let n = -293 + 710. What are the prime factors of n? 3, 139 Let s = 1133 + -892. What are the prime factors of s? 241 Suppose -2a - 284 + 4040 = 0. What are the prime factors of a? 2, 3, 313 Let d(x) = x2 - 3x - 3. Let r be d(4). Let g(a) = -4a2 + 7 + 12a*3 - 2 + 2a + 2a2 - 6. What are the prime factors of g(r)? 11 Let p be (0 + 52/4)/((-2)/(-88)). Suppose -12u + 124 = -p. What are the prime factors of u? 2, 29 Let q = 7559 + -2774. List the prime factors of (q/12)/5 - (-3)/(-4). 79 Let n(z) = -3z - 11. Let q be n(-5). Suppose 0 = -2j - 2d + 48, 3j + 24 = qj - 2d. What are the prime factors of j? 2, 3 Let k(u) = -1598u - 129. List the prime factors of k(-3). 3, 5, 311 Suppose 35299 = 17d - 41490. List the prime factors of d. 4517 Let b(r) = -r*2 + 2r - 1. Let j be b(3). Let f be 4 + (-3 - -3) - j. List the prime factors of (2/(-8))/(f/(-1504)). 47 Suppose -39w + 32w + 2184 = 0. What are the prime factors of w? 2, 3, 13 Suppose 18a = 4o + 16a - 3878, -966 = -o + 4a. List the prime factors of o. 2, 5, 97 Let g be -1 + (-3 - 2) - 3. Let s(a) = a*3 + 10a*2 + 3a - 16. List the prime factors of s(g). 2, 19 Let n be (-2)/6 + (-120)/(-9). Suppose r - 28 = -3r. Let i = n - r. What are the prime factors of i? 2, 3 Let t(q) = q3 + 3q*2 + 5q + 3. Let o be t(-3). Let g(p) = p*3 + 13p*2 + 6p + 3. What are the prime factors of g(o)? 3, 5 What are the prime factors of 26625/24 + (-81)/216? 1109 Let h be -18/4 - -14. Let r be 30/h - 6/(-4). Suppose -4i + 21 + 7 = c, -rc + 133 = -5i. List the prime factors of c. 2 Let w be 2(-3)/18-15. Let t = w + -5. Suppose 5u + 0u - 30 = t. What are the prime factors of u? 2, 3 Let f(i) = -i*3 + 12i*2 - 15i - 8. Let a(q) = q2 - q + 1. Let u(y) = a(y) - f(y). List the prime factors of u(10). 7 Let c be 14/56 + (-322)/8. Let f = -4 + 2. What are the prime factors of (56/c)/(f/10)? 7 Let s(p) = p2 + 7p + 2. Let l be s(-7). Suppose 2k = -lk. Suppose kz + 116 = 4z. What are the prime factors of z? 29 Suppose 0 = u - 2k - 2229, -16u + 11u = 3k - 11132. List the prime factors of u. 17, 131 Let g(h) be the third derivative of 6h*2 + 0h - 19/12h4 - 1/6h*3 + 0. List the prime factors of g(-1). 37 Suppose 0 = 30p - 26p - 248. Suppose l - p = -i - 0i, 0 = -5l - 4i + 309. What are the prime factors of l? 61 List the prime factors of 50/150 - 299/(-3). 2, 5 Suppose 0 = -2j + 5i + 1643, -1673 = -2j - 5i - 0i. List the prime factors of j. 829 What are the prime factors of 1 + -11 + 3852 + -1? 23, 167 Let y be 6(3 - (-28)/(-12)). Suppose yk = 4j - 3j - 51, -j + 26 = k. List the prime factors of j. 31 Let f(h) = -1597h - 230. What are the prime factors of f(-2)? 2, 3, 13, 19
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automatically generated or I have to enter here } I know slug is generated automatically but what about the user info? I'm getting confused here? And how do I get user info from userId? (I have a route /users/:id though but don't know how to use it in this case) User Model const userSchema = new Schema({ username: { type: String, required: true }, email: { type: String, required: true }, password: { type: String, required: true }, }, { timestamps: true }) Post Model const postSchema = new Schema({ title: { type: String, required: true }, description: { type: String, required: true }, userId: { type: Schema.Types.ObjectId, ref: "User" }, slug: { type: String, slug: "title" } }, { timestamps: true } authmiddleware.js function generateToken(payload) { return jwt.sign(payload, "secret") } function verifyToken(req, res, next) { const token = req.headers.Authorization if (!token) return res.json({ msg: "unauthorized"}) jwt.verify(token,"secret",(err, decoded) => { if (err) return res.json({ error: "unuthorized" }) req.user = decoded next() }) } module.exports = {generateToken, verifyToken } routes/posts.js router.post("/new", authmiddleware.verifyToken, postControllers.newPost) postControllers/newPost.js newPost: (req, res) => { Post.create(req.body, (err, newPost) => { if (err) console.log(err) if (!newPost) { return res.json({ message: "No post found" }) } else if (newPost) { return res.json({ post: newPost }) } }) } When I checked in postman by entering this info as body(and sent token in headers) { "title": "My first post", "description": "My first post description" } I got this result: { "post": { "_id": "5e3028ded3e24b55e06baaf2", "title": "My first post", "description": "My first post description" "createdAt": "2020-01-28T12:28:14.331Z", "updatedAt": "2020-01-28T12:28:14.331Z", "slug": "my-first-post", "__v": 0 } } But I also want to get the user info in this. Update: So, I got the userId in the newly created post object. I was doing this earlier: newPost: (req, res) => { Post.create(req.body, req.user.userId, (err, newPost) => { if (err) console.log(err) if (!newPost) { return res.json({ message: "No post found" }) } else if (newPost) { return res.json({ post: newPost }) } }) } And got and error: { "error": { "message": "Parameter \"obj\" to Document() must be an object, got 5e2f365d41ff66569445eec2", "name": "ObjectParameterError" } } Then I did this I got the result: newPost: (req, res) => { const data = { title: req.body.title, description: req.body.description, userId: req.user.userId } Post.create(data, (err, newPost) => { if (err) console.log(err) if (!newPost) { return res.json({ message: "No post found" }) } else if (newPost) { return res.json({ post: newPost }) } }) } It shouldn't be happening. No? A: You can put the logged in user's id to the request in your auth middleware, and acccess the user id in your route. Let's say you have a such auth middleware: const jwt = require("jsonwebtoken"); module.exports = function(req, res, next) { let token; if ( req.headers.authorization && req.headers.authorization.startsWith("Bearer") ) { token = req.headers.authorization.split(" ")[1]; } if (!token) return res.status(401).send("Access denied. No token provided."); try { const decoded = jwt.verify(token, "JWT_PRIVATE_KEY"); req.user = decoded; next(); } catch (ex) { res.status(400).send("Invalid token."); } }; I assume you send the authorization token in the Authorization header in the format Bearer TOKEN....... If you send the token in a different header, you need to adjust code to read token accordingly. Now when you apply this middleware to your route, you can read the user id from request, and use it. const Post = require("../models/post"); const auth = require("../middleware/auth"); router.post("/posts", [auth], async (req, res) => { const result = await Post.create({ title: req.body.title, description: req.body.description, user: req.user._id //comes from auth middleware }); res.send(result); }); For this to work, you need to include the user id in the token when you sign it. const token = jwt.sign({ _id: user._id }, "JWT_PRIVATE_KEY"); Scalable memory allocation using jemalloc - Anon84 http://www.facebook.com/note.php?note_id=480222803919 ====== gnosis Previously on HN: <http://news.ycombinator.com/item?id=1258935> Q: Elementary Submodels in Set Theory I was reading the following summary on elementary submodels: http://boolesrings.org/mpawliuk/2012/01/26/a-practical-guide-to-using-countable-elementary-submodels/ Say $M\prec N$. The link above indicates (Super Useful Fact) that any set definable by parameters in $M$ is an element of $M$. In particular, let $\phi(v_1,v_2)$ be a first order formula of set theory. My understanding of this is that, if $x\in M$ and $\{t: t\in N\wedge \phi(x,t)\}\in N$, then $\{t: t\in M\wedge \phi(x,t)\}\in M$. What I am wondering is whether we can guarantee that $\{t: t\in M\wedge \phi(x,t)\}\subset M$. As a first order sentence, we have ($\exists z) \ (\forall t)t\in z\leftrightarrow(\phi(x,t))$ Assuming this is satisfied by $N$, it must be satisfied by $M$ since $M\prec N$. In particular, there exists $z'\in M$ such that $(\forall t\in M)t\in z'\leftrightarrow(\phi(x,t))$. Certainly, $z'$ is a subset of the class we want but perhaps it contains elements which are not in $M$. Can we guarantee that $z'\subset M$? A: This all comes from the definition of elementary, and is a little more delicate than you might think. Model theoretically, a model $M$ is an elementary submodel of a model $N$ if $M$ is a submodel of $M$ (the universe of $M$ is a subset of that of $N$, and all interpretations of function/predicate/constant symbols are just the restrictions of those of $N$), and every statement about the elements of $M$ is true in $N$ iff it is true in $M$; meaning that given a formula $\varphi ( x_1 , \ldots , x_n )$ and $a_1 , \ldots , a_n \in M$, $$M \models \varphi ( a_1 , \ldots , a_n ) \Leftrightarrow N \models \varphi ( a_1
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44383, 47452, 15, 7532, 422, 33501, 6031, 497, 10098, 326, 1073, 13083, 247, 10665, 7155, 273, 253, 7970, 48866, 281, 253, 6150, 13, 8479, 352, 281, 23973, 25060, 15, 5488, 13, 8485, 40784, 273, 46936, 18549, 497, 908, 323, 6069, 5175, 13, 285, 627, 4961, 247, 48541, 273, 2864, 18086, 29492, 285, 27304, 15, 187, 187, 688, 253, 806, 629, 273, 4695, 8170, 10497, 7407, 247, 5460, 2341, 8891, 13, 247, 28938, 273, 1097, 13978, 285, 7236, 13, 26668, 407, 32459, 595, 5412, 9208, 13, 11741, 11319, 13 ]	was done on the fly as the German advance was already sweeping through the Soviet border zone. The German invasion also hampered the effectiveness of the Soviet response by shattering their communications in the war's early stages; many Soviet leaders were unable to gather reliable information about the positions of German forces until it was too late to effect an orderly evacuation. There was also a desire on the part of Soviet officials to forestall any evacuations until it was absolutely necessary, the marching orders were often to continue factory production until the eve of occupation before hurriedly dismantling and transporting factory equipment, and destroying what couldn't be moved in time. As a result of the delay in evacuations, they were often carried out under German aerial bombardment, which led to additional confusion among the frightened citizenry. Historian Rebecca Manley describes these early evacuations as being charactered by “three phenomena: the 'flight' of officials, the flight of the population, and 'panic'”. The early flight of Soviet officials who were supposed to manage the evacuation was roundly condemned by Soviet leaders, but often their retreat resulted from a realisation that evacuation procedures had started too late, and that there was no way to effectively execute it. Additionally, Soviet officials who remained in a city captured by German forces feared execution by Nazis on the hunt for communists. Avoiding that, the officials knew that they would be subject to intense interrogation as to what happened by suspicious Soviets upon returning to the fold. Despite these setbacks in the implementation of evacuation policy early in the war, around 12 million Soviet citizens successfully evacuated in 1941, even if a number of these were the result of disorganised, “spontaneous self-evacuation,” and another 4.5 million evacuated the following year. In addition, the factories that were successfully evacuated to the Central Asian rear would help provide the productive capacity the Soviets needed to eventually win the war, as well as preventing the Germans from acquiring additional industrial resources. By providing a safe haven from the German advance for Soviet citizens, Central Asia played a critical role in securing Allied victory. The evacuation itself was only part of the difficulty, however, as evacuees arriving in Central Asia faced many trials and tribulations. Due to the haphazard nature of evacuation, many labourers did not arrive with their factory, and had to find labour on their own, though jobs were hard to come by. Additionally, cities like Tashkent became overwhelmed at the sheer volume of people arriving at its gates and had great difficulty supplying the food and shelter necessary for evacuees. Upon arrival, many evacuees died of illness or starvation in extreme poverty in Central Asia. Uzbek officials set up aid stations at Tashkent, which were mirrored at other railway stations to help combat the poverty, but they could only do so much as little could be spared economically for the war effort. Despite these troubles, the ability of Central Asia to absorb Soviet industry and population to the extent that it did and in the harried manner that it did was impressive. The Germans certainly didn't foresee the preparedness of Soviet Central Asia, and in the end they paid dearly for it. Since 1991 From 1988 to 1992, a free press and multi-party system developed in the Central Asian republics as perestroika pressured the local Communist parties to open up. What Svat Soucek calls the "Central Asian Spring" was very short-lived, as soon after independence former Communist Party officials recast themselves as local strongmen. Political stability in the region has mostly been maintained, with the major exception of the Tajik Civil War that lasted from 1992 to 1997. 2005 also saw the largely peaceful ousting of Kyrgyz president Askar Akayev in the Tulip Revolution and an outbreak of violence in Andijan, Uzbekistan. Much of the population of Soviet Central Asia was indifferent to the collapse of the Soviet Union, even the large Russian populations in Kazakhstan (roughly 40% of the total) and Tashkent, Uzbekistan. Aid from the Kremlin had also been central to the economies of Central Asia, each of the republics receiving massive transfers of funds from Moscow. Independence largely resulted from the efforts of the small groups of nationalistic, mostly local intellectuals, and from little interest in Moscow for retaining the expensive region. While never a part of the Soviet Union, Mongolia followed a somewhat similar path. Often acting as the unofficial sixteenth Soviet republic, it shed the communist system only in 1996, but quickly ran into economic problems. See: History of independent Mongolia. The economic performance of the region since independence has been mixed. It contains some of the largest reserves of natural resources in the world, but there are important difficulties in transporting them. Since it lies farther from the ocean than anywhere else in the world, and its southern borders lay closed for decades, the main trade routes and pipelines run through Russia. As a result, Russia still exerts more influence over the region than in any other former Soviet republics. Nevertheless, the rising energy importance of the Caspian Sea entails a great involvement in the region by the US. The former Soviet republics of the Caucasus now have their own US Special Envoy and inter-agency working groups. Former US Secretary of Energy Bill Richardson had claimed that "the Caspian region will hopefully save us [the US] from total dependence on Middle East oil". Some analysts, such as Myers Jaffe and Robert A. Manning, estimate however that US' entry into the region (with initiatives such as the US-favored Baku-Tbilisi-Ceyhan pipeline) as a major actor may complicate Moscow's chances of making a decisive break with its past economic mistakes and geopolitical excesses in Central Asia. They also regard as a myth the assertion that Caspian oil and gas will be a cheaper and more secure alternative to supplies from the Persian Gulf. Despite these reservations and fears, since the late 1980s, Azerbaijan, Kazakhstan, and Turkmenistan have gradually moved to centre stage in the global energy markets and are now regarded as key factors of the international energy security. Azerbaijan and Kazakhstan in particular have succeeded in attracting massive foreign investment to their oil and gas sectors. According to Gawdat Bahgat, the investment flow suggests that the geological potential of the Caspian region as a major source of oil and gas is not in doubt. Russia and Kazakhstan started a closer energy co-operation in 1998, which was further consolidated in May 2002, when Presidents Vladimir Putin and Nursultan Nazarbayev signed a protocol dividing three gas fields – Kurmangazy, Tsentralnoye, and Khvalynskoye – on an equal basis. Following the ratification of bilateral treaties, Russia, Kazakhstan and Azerbaijan declared that the northern Caspian was open for business and investment as they had reached a consensus on the legal status of the basin. Iran and Turkmenistan refused however to recognise the validity of these bilateral agreements; Iran is rejecting any bilateral agreement to divide the Caspian. On the other hand, US' choices in the region (within the framework of the so-called "pipeline diplomacy"), such as the strong support of the Baku pipeline (the project was eventually approved and was completed in 2005), reflect a political desire to avoid both Russia and Iran. Increasingly, other powers have begun to involve themselves in Central Asia. Soon after the Central Asian states won their independence, Turkey began to look east, and a number of organizations are attempting to build links between the western and eastern Turks. Iran, which for millennia had close links with the region, has also been working to build ties and the Central Asian states now have good relations with the Islamic Republic. One important player in the new Central Asia has been Saudi Arabia, which has been funding the Islamic revival in the region. Olcott notes that soon after independence Saudi money paid for massive shipments of Qur'ans to the region and for the construction and repair of a large number of mosques. In Tajikistan alone an estimated 500 mosques per year have been erected with Saudi money. The formerly atheistic Communist Party leaders have mostly converted to Islam. Small Islamist groups have formed in several of the countries, but radical Islam has little history in the region; the Central Asian societies have remained largely secular and all five states enjoy good relations with Israel. Central Asia is still home to a large Jewish population, the largest group being the Bukharan Jews, and important trade and business links have developed between those that left for Israel after independence and those remaining. The People's Republic of China sees the region as an essential future source of raw materials; most Central Asian countries are members of the Shanghai Cooperation Organization. This has affected Xinjiang and other parts of western China that have seen infrastructure programs building new links and also new military facilities. Chinese Central Asia has been far from the centre of that country's economic boom and the area has remained considerably poorer than the coast. China also sees a threat in the potential of the new states to support separatist movements among its own Turkic minorities. One important Soviet legacy that has only gradually been appreciated is the vast ecological destruction. Most notable is the gradual drying of the Aral Sea. During the Soviet era, it was decided that the traditional crops of melons and vegetables would be replaced by water-intensive growing of cotton for Soviet textile mills. Massive irrigation efforts were launched that diverted a considerable percentage of the annual inflow to the sea, causing it to shrink steadily. Furthermore, vast tracts of Kazakhstan were used for nuclear testing, and there exists a plethora of decrepit factories and mines. In the first part of 2008 Central Asia experienced a severe energy crisis, a shortage of both electricity and fuel, aggravated by abnormally cold temperatures, failing infrastructure,
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23974, 9657, 1662, 18, 28, 187, 14, 313, 301, 654, 2925, 6998, 24475, 19570, 22226, 11145, 24475, 19570, 10477, 2925, 6998, 24475, 23974, 9657, 1662, 18, 28, 187, 14, 313, 301, 654, 2925, 6998, 19238, 19570, 22226 ]	ohistochemical tests revealed that the neoplastic cells were immunoreactive for S-100 and vimentin and showed no staining with cytokeratin. The animal had a local recurrence of the tumor 3 months after the initial excision. This is the first case of malignant melanoma with osteoid formation reported in animals.const createEvent = require("aws-event-mocks"); const SnsEvent = require("../src/SnsEvent"); const createSnsEvent = message => { return createEvent({ template: "aws:sns", merge: { Records: [ { Sns: { Subject: "the subject", Message: message } } ] } }); }; describe("SnsEvent", () => { describe("#message", () => { it("should be able to parse from raw event", async () => { const snsEvent = SnsEvent.fromRaw(createSnsEvent("plain text")); expect(snsEvent.message).toEqual("plain text"); expect(snsEvent.subject).toEqual("the subject"); }); it("should automatically parse JSON", async () => { const snsEvent = SnsEvent.fromRaw( createSnsEvent(JSON.stringify({ foo: "bar" })) ); expect(snsEvent.message).toEqual({ foo: "bar" }); }); }); }); Q: What is more efficient in python new array creation or in place array manipulation? Say I have an array with a couple hundred elements. I need to iterate of the array and replace one or more items in the array with some other item. Which strategy is more efficient in python in terms of speed (I'm not worried about memory)? For example: I have an array my_array = [1,2,3,4,5,6] I want to replace the first 3 elements with one element with the value 123. Option 1 (inline): my_array = [1,2,3,4,5,6] my_array.remove(0,3) my_array.insert(0,123) Option2 (new array creation): my_array = [1,2,3,4,5,6] my_array = my_array[3:] my_array.insert(0,123) Both of the above will options will give a result of: >>> [123,4,5,6] Any comments would be appreciated. Especially if there is options I have missed. A: If you want to replace an item or a set of items in a list, you should never use your first option. Removing and adding to a list in the middle is slow (reference). Your second option is also fairly inefficient, since you're doing two operations for a single replacement. Instead, just do slice assignment, as eiben's answer instructs. This will be significantly faster and more efficient than either of your methods: >>> my_array = [1,2,3,4,5,6] >>> my_array[:3] = [123] >>> my_array [123, 4, 5, 6] A: arr[0] = x replaces the 0th element with x. You can also replace whole slices. >>> arr = [1, 2, 3, 4, 5, 6] >>> arr[0:3] = [8, 9, 99] >>> arr [8, 9, 99, 4, 5, 6] >>> And generally it's unclear what you're trying to achieve. Please provide more information or an example. OK, as for your update. The remove method doesn't work (remove needs one argument). But the slicing I presented works for your case too: >>> arr [8, 9, 99, 4, 5, 6] >>> arr[0:3] = [4] >>> arr [4, 4, 5, 6] I would guess it's the fastest method, but do try it with timeit. According to my tests it's twice as fast as your "new array" approach. <html><head><meta http-equiv="content-type" content="text/html; charset=utf-8"> <style> .KEYW {color: #933;} .COMM {color: #bbb; font-style: italic;} .NUMB {color: #393;} .STRN {color: #393;} .REGX {color: #339;} .linenumber {border-right: 1px dotted #666; color: #666; font-style: normal;} </style></head><body><pre><span class='linenumber'> 1</span> <span class="COMM">/** <span class='linenumber'> 2</span> * @namespace Stores information about the state of the keyboard <span class='linenumber'> 3</span> /</span><span class="WHIT"> <span class='linenumber'> 4</span> </span><span class="KEYW">var</span><span class="WHIT"> </span><span class="NAME">Keyboard</span><span class="WHIT"> </span><span class="PUNC">=</span><span class="WHIT"> </span><span class="PUNC">{</span><span class="WHIT"> <span class='linenumber'> 5</span> </span><span class="COMM">/* <span class='linenumber'> 6</span> * Hash of keys and whether they are down <span class='linenumber'> 7</span> * @type Hash (String -> Boolean) <span class='linenumber'> 8</span> /</span><span class="WHIT"> <span class='linenumber'> 9</span> </span><span class="NAME">keys</span><span class="PUNC">:</span><span class="WHIT"> </span><span class="KEYW">new</span><span class="WHIT"> </span><span class="NAME">Hash</span><span class="PUNC">(</span><span class="PUNC">)</span><span class="PUNC">,</span><span class="WHIT"> <span class='linenumber'> 10</span> </span><span class="COMM">/* <span class='linenumber'> 11</span> * Whether Cartagen will be controlled by the keyboard <span class='linenumber'> 12</span> * @type Boolean <span class='linenumber'> 13</span> /</span><span class="WHIT"> <span class='linenumber'> 14</span> </span><span class="NAME">key_input</span><span class="PUNC">:</span><span class="WHIT"> </span><span class="KEYW">false</span><span class="PUNC">,</span><span class="WHIT"> <span class='linenumber'> 15</span> </span><span class="PUNC">}</span><span class="WHIT"> <span class='linenumber'> 16</span> </span></pre></body></html>// // Generated by class-dump 3.5 (64 bit) (Debug version compiled Oct 15 2018 10:31:50). // // class-dump is Copyright (C) 1997-1998, 2000-2001, 2004-2015 by Steve Nygard. // #import <AddressBook/NSObject-Protocol.h> @class ABGroupActionScope, ABGroupBrowsingContext, ABGroupDragScope, ABGroupDropScope, ABGroupImportFilesScope, ABGroupSearchingContext, ABSmartGroup, NSString; @protocol ABGroupActionHelper, ABGroupCutHelper, ABGroupDeleteHelper, ABGroupDragHelper, ABGroupDropHelper, ABGroupRenameHelper, ABGroupSelectHelper; @protocol ABGroupHelperFactory <NSObject> - (id <ABGroupActionHelper>)makeImportFilesHelper:(ABGroupImportFilesScope )arg1 showImportConfirmation:(BOOL)arg2; - (id <ABGroupActionHelper>)makeEditSmartGroupHelper:(ABSmartGroup )arg1; - (id <ABGroupActionHelper>)makeCreateSmartGroupFromSearchHelper; - (id <ABGroupActionHelper>)makeCreateSmartGroupHelper; - (id <ABGroupSelectHelper>)makeSectionSelectHelperWithIdentifier:(NSString )arg1; - (id <ABGroupSelectHelper>)makeSearchingSelectHelper:(ABGroupSearchingContext )arg1; - (id <ABGroupSelectHelper>)makeBrowsingSelectHelper:(ABGroupBrowsingContext )arg1; - (id <ABGroupDragHelper>)makeDragHelper:(ABGroupDragScope )arg1; - (id <ABGroupDropHelper>)makeDropHelper:(ABGroupDropScope )arg1; - (id <ABGroupDeleteHelper>)
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5232, 15, 5089, 15, 9494, 5726, 15, 788, 31780, 42049, 318, 33937, 366, 15, 12812, 187, 50254, 50274, 9, 346, 1552, 310, 7964, 417, 271, 4579, 2953, 3, 187, 50254, 50274, 13, 42519, 42049, 318, 15, 19504, 7191, 15, 4756 ]	what dying patients teach you. After your death, when most of you for the first time realize what life here is all about, you begin to see that your life here is almost nothing but the sum total of every choice you have made during every moment of your life. Your thoughts, which you are responsible for, are as real as your deeds.You will begin to realize that every word and every deed affects your life and has also touched thousands of lives. I believe that we are solely responsible for our choices, and we have to accept the consequences of every deed, word, and thought throughout our lifetime. There is within each one of us a potential for goodness beyond our imagining; for giving which seeks no reward; for listening without judgment; for loving unconditionally.” Daniel Webster "One may live as a conqueror, a king or a magistrate; but he must die as a man. The bed of death brings every human being to his pure individuality; to the intense contemplation of that deepest and most solemn of all relations, the relation between the creature and his Creator. Here it is that fame and renown cannot assist us; that all external things must fail to aid us; that even friends, affection and human love and devotedness cannot succor us." Dr. Eben Alexander, III on his message from the after-life "You are loved and cherished, dearly, forever. You have nothing to fear. There is nothing you can do wrong over there." George Bernard Shaw "This is the true joy in life - that being used for a purpose recognized by yourself as a mighty one - that being a force of nature instead of a feverish, selfish, little clod of ailments and grievances complaining that the world will not devote itself to making you happy. I am of the opinion that my life belongs to the whole community. As long as I live, it is my privilege to do for it whatever I can. I want to be thoroughly used up when I die, for the harder I work, the morel live. I rejoice in life for its own sake. Life is no brief candle for me. There is a sort of splendid torch which I've got hold of for the moment and I want to make it burn as brightly as possible before handing it on to future generations." "If you wish to upset the law that all crows are black, you must not seek to show that no crows are; it is enough if you can prove one single crow be white." Charles H. Duell, Commissioner U.S. Patent Office 1899 "Everything that can be invented has been invented." Chief Seattle circa 1850: "This we know. All things are connected like the blood which unites one family. All things are connected. Whatever befalls the earth befalls the sons of earth. Man did not weave the web of life; he is merely a strand of it. Whatever he does to the web, he does to himself." Dr. Albert Einstein “You can’t solve a problem using the same level of thinking that got you into that problem”. "Give"Given the millions of billions of Earth-like planets, life elsewhere in the Universe without a doubt, does exist. In the vastness of the Universe we are not alone." "There is not the slightest indication that nuclear energy will ever be obtainable. It would mean the atom would have to be shattered at will." Simon Cameron, U.S. Senator 1901> "I am tired of all this sort of thing called science here ... We have spent millions in that sort of thing for the last few years, and it is time it should be stopped." Wilbur Wright, 1908 "I confess that in 1901 I said to my brother Orville that man would not fly for fifty years. Two years later we ourselves made flights. This demonstration of my impotence as a prophet gave me such a shock that ever since I have distrusted myself and avoided all predictions." Nikola Tesla "Of all the frictional resistance, the one that most retards human movement is ignorance, what Buddha called "the greatest evil in the world." The friction which results from ignorance can be reduced only by the spread of knowledge and the unification of the heterogeneous elements of humanity. No effort could be better spent." "No matter what we attempt to do, no matter to what fields we turn our efforts, we are dependent on power. We have to evolve means of obtaining energy from stores which are forever inexhaustible, to perfect methods which do not imply consumption and waste of any material whatever. If we use fuel to get our power, we are living on our capital and exhausting it rapidly. This method is barbarous and wantonly wasteful and will have to be stopped in the interest of coming generations." Chinese proverb “If we do not change direction, we are likely to end up exactly where we are headed”. Albert A. Michelson German Born American Physicist 1894 "The more important fundamental laws and facts of physical science have all been discovered, and these are now so firmly established that the possibility of their ever being supplanted in consequence of new discoveries is exceedingly remote.... Our future discoveries must be looked for in the sixth place of decimals." Margret Mead “Never doubt the power of a small group of people to change the world. Nothing else ever has”. Buddha “In order to fully understand, you have to be one with what you want to understand”. Paul Davies “You are … host to a billion or so atoms that once belonged to Jesus Christ, or Julius Caesar, or the Buddha, or the tree that the Buddha once sat beneath”. Niccollo Machavelli circa 1500 “There is nothing more difficult to take in hand, more perilous to conduct or more uncertain in its success than to take the lead in the introduction of a new order of things". Dr. Steven Hawking - A Brief History of Time “Ever since the dawn of civilization, people have not been content to see events as unconnected and inexplicable. They have craved an understanding of the underlying order in the world. Today we still yearn to know why we are here and where we came from. Our goal is nothing less than a complete description of the universe we live in.” Dr. Edgar Mitchell on reflections of his trip to the moon: “When I went to the moon, I was as pragmatic a test pilot, engineer, and scientist as any of my colleagues … But there was another aspect to my experience during Apollo 14, and it … began with the breathtaking experience of seeing planet earth floating in the vastness of space. The first thing that came to mind as I looked at earth was its incredible beauty … a splendid blue and white jewel suspended against a velvet black sky. How peacefully, how harmoniously, how marvelously it seemed to fit into the evolutionary pattern by which the universe is maintained. In a peak experience, the presence of divinity became almost palpable and I knew that life in the universe was not just an accident based on random process. … It was knowledge gained through private subjective awareness, but it was - and still is - every bit as real as the objective data upon which, say, the navigational program or the communications system were based. Clearly, the universe had meaning and direction … an unseen dimension behind the visible creation that gives it an intelligent design and that gives life purpose”.module MetaTests exposing (all) import Expect exposing (Expectation) import Form.Error exposing (ErrorValue) import Form.Test.Helpers import Form.Test.ValidationExpectation as ValidationExpectation import Form.Validate as Validate exposing (Validation, string) import Test exposing (..) all : Test all = describe "meta tests" [ test "expect success but get error" <\| \() -> let actual = Form.Test.Helpers.getValidationExpectation Validate.email ( "This is definitely not an email address" , ValidationExpectation.Valid ) expected = ValidationExpectation.Invalid Form.Error.InvalidEmail \|> Expect.equal ValidationExpectation.Valid in actual \|> Expect.equal expected , test "expect success get success" <\| \() -> let actual = Form.Test.Helpers.getValidationExpectation Validate.email ( "[email protected]" , ValidationExpectation.Valid ) in actual \|> Expect.equal Expect.pass , test "expected error" <\| \() -> let actual = Form.Test.Helpers.getValidationExpectation Validate.email ( "This is definitely not an email address" , ValidationExpectation.Invalid Form.Error
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3629, 1340, 15, 187, 14, 19, 16, 24, 13, 608, 13, 12036, 187, 12501, 428, 19, 16, 22, 13, 374, 16, 22, 13, 428, 23, 13, 428, 18, 16, 21, 275, 16317, 1340, 15, 187, 19, 16, 22, 13, 428, 18, 16, 21, 13, 428, 19, 16, 22, 13, 428, 23, 187, 12501, 428, 23, 1508, 13, 374, 13, 495, 13, 577, 275, 16317, 1340, 15, 187, 21, 13, 495, 13, 374, 13, 428, 23, 1508, 187, 12501, 428, 18, 13, 428, 2504, 13, 608, 13, 1249, 275, 11052, 1340, 15, 187, 805, 13, 608, 13, 428, 18, 13, 428, 2504, 187, 15462, 374, 13, 495, 13, 1249, 13, 428, 19, 275, 20474, 1340, 15, 187, 14, 19, 13, 374, 13, 495, 13, 1249, 187, 12501, 428, 17, 15, 18, 13, 428, 17, 15, 520, 13, 428, 17, 15 ]	. -4, -2, -1, 6 Sort -1/4, 3/2, 25. -1/4, 3/2, 25 Put 25, -5, -4, -3 in ascending order. -5, -4, -3, 25 Sort -102, 5, 4. -102, 4, 5 Sort 1/4, -2.89, -0.1, 1, 4. -2.89, -0.1, 1/4, 1, 4 Put 1, 10, -11 in descending order. 10, 1, -11 Sort -1/3, 1/4, 18/13, 2 in increasing order. -1/3, 1/4, 18/13, 2 Sort -255, -4, -5 in increasing order. -255, -5, -4 Sort -6, -1, -15 in ascending order. -15, -6, -1 Put 969, 4, 2 in descending order. 969, 4, 2 Put 5, 1/5, 70, 2/7, 1/3 in descending order. 70, 5, 1/3, 2/7, 1/5 Sort -5, 3/5, 50/11 in descending order. 50/11, 3/5, -5 Sort -0.4, -0.2, -0.05, -5 in increasing order. -5, -0.4, -0.2, -0.05 Put -4, 1, 19 in decreasing order. 19, 1, -4 Put -1, -33, -5, -4 in increasing order. -33, -5, -4, -1 Sort -5, -3, 1, 6. -5, -3, 1, 6 Put -1, 18, -0.3, 0 in ascending order. -1, -0.3, 0, 18 Put -276, -1, 3/4, -2 in ascending order. -276, -2, -1, 3/4 Put -684, 1, 0.1 in ascending order. -684, 0.1, 1 Put 3, 4, -0.9, 0.1 in descending order. 4, 3, 0.1, -0.9 Put 4, 3, 28, 5 in decreasing order. 28, 5, 4, 3 Put 20, -4, -5 in decreasing order. 20, -4, -5 Put -9, 3, -4, 0, 15 in ascending order. -9, -4, 0, 3, 15 Put -6, 5/2, 0.05 in descending order. 5/2, 0.05, -6 Sort 2, -97, -9 in increasing order. -97, -9, 2 Sort 2, 1, -1.6. -1.6, 1, 2 Sort 0.22, -4, 2 in decreasing order. 2, 0.22, -4 Sort 4, 641, -5. -5, 4, 641 Put -80, -1, 3 in increasing order. -80, -1, 3 Put -1, -4, 4, 831 in decreasing order. 831, 4, -1, -4 Put -2, -169, 2 in decreasing order. 2, -2, -169 Sort -35, 1/2, 7/4. -35, 1/2, 7/4 Put 10, 4, -1/3, 0 in descending order. 10, 4, 0, -1/3 Sort -1, -2, -189, 4, 2 in decreasing order. 4, 2, -1, -2, -189 Put -6, 2, -0.052, 0 in increasing order. -6, -0.052, 0, 2 Sort 268, -2, -3. -3, -2, 268 Sort -1/2, 15047, 3. -1/2, 3, 15047 Sort 5, 4, -12, -6, -4 in decreasing order. 5, 4, -4, -6, -12 Sort -1, 1, -2, 27 in increasing order. -2, -1, 1, 27 Sort 3, -4, 1, 2, 19 in descending order. 19, 3, 2, 1, -4 Sort -5, 0, -0.1, -0.2 in descending order. 0, -0.1, -0.2, -5 Sort -0.4, -5, 0.4, -0.5 in increasing order. -5, -0.5, -0.4, 0.4 Put -90, 24, 1 in descending order. 24, 1, -90 Sort 7, 1, -4 in ascending order. -4, 1, 7 Sort 4, -4, 339 in descending order. 339, 4, -4 Put -4/3, -26, -2/7 in descending order. -2/7, -4/3, -26 Sort -5, -47, -19 in ascending order. -47, -19, -5 Sort -2/3, 9/4, 2, 2/9. -2/3, 2/9, 2, 9/4 Sort 5, -1325, 3. -1325, 3, 5 Sort -3/8, -0.1, 0.9, 0.047 in decreasing order. 0.9, 0.047, -0.1, -3/8 Sort -4, 0, -0.1, 2 in decreasing order. 2, 0, -0.1, -4 Put 7.04, -3/7, -0.5 in decreasing order. 7.04, -3/7, -0.5 Sort 50, -5, 3. -5, 3, 50 Sort 0.2, -0.3, 2/17, -0.4, -3/2 in ascending order. -3/2, -0.4, -0.3, 2/17, 0.2 Put -2, -5, 28 in descending order. 28, -2, -5 Sort 1/47, 3, -1. -1, 1/47, 3 Sort -4, 0.2, -26, -2, 0.1. -26, -4, -2, 0.1, 0.2 Sort 5, -10, 6. -10, 5, 6 Put 0.2, -5/2, 0, -3 in increasing order. -3, -5/2, 0, 0.2 Put 12, -1, 8, 3 in descending order. 12, 8, 3, -1 Put -257, -1/7, -0.4, -2/3 in descending order. -1/7, -0.4, -2/3, -257 Sort -4, -0.2, 0.4, 55 in increasing order. -4, -0.2, 0.4, 55 Sort -3, -169, -1/4 in descending order. -1/4, -3, -169 Sort 4, 0.3, 2/9. 2/9, 0.3, 4 Sort 0.03, 0.4, 14 in increasing order. 0.03, 0.4, 14 Put 4, -1, 3, 16 in descending order. 16, 4, 3, -1 Sort 3/2, 5, 1, -5 in increasing order. -5, 1, 3/2, 5 Sort -0.01, -0.2, 5 in decreasing order. 5, -0.01, -0.2 Put 0.4, -5, -0.2, 20, -2/5 in decreasing order. 20, 0.4, -0.2, -2/5, -5 Sort -0.1, 5, 3/2, -0.5, -3/13. -0.5, -3/13, -0.1, 3/2, 5 Put -1, -62, -5 in ascending order. -62, -5, -1 Sort 160, 5, -2/7 in increasing order. -2/7, 5, 160 Put -2/5, 2/5, -6, -1/4 in descending order. 2/5, -1/4, -2/5, -6 Put -623, 2, 3, 4 in descending order. 4, 3, 2, -623 Put -1, -47, 5, 12 in decreasing order. 12, 5, -1, -47 Sort 2, 3, 12, -2 in ascending order. -2, 2, 3, 12 Put -0.1, -0.01, -0.
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12, 32303, 12, 39, 20, 281, 3186, 323, 1735, 12340, 598, 273, 253, 1655, 4236, 2505, 544, 88, 16, 80, 4645, 253, 29856, 62, 187, 50266, 12467, 7456, 15, 16601, 12094, 9, 187, 50262, 12094, 15, 9867, 19030, 4312, 5683, 20696, 45089, 13, 187, 50262, 20842, 14324, 15, 13904, 13, 187, 50262, 12094, 6998, 15, 9867, 1898, 34435, 13, 187, 50262, 12599, 1320, 15, 52, 1070, 12094, 9867, 34435, 559, 19242, 15, 11133, 15, 14324, 38830, 1080, 559 ]	jandro Granados-Villafuerte (Granados) appeals the sentence he received following his guilty plea conviction for being found illegally in the United States after having been previously removed. Granados argues that one criminal history point should not have been assigned to his 2010 Oklahoma open container traffic offense. * Pursuant to 5TH CIR. R. 47.5, the court has determined that this opinion should not be published and is not precedent except under the limited circumstances set forth in 5TH CIR. R. 47.5.4. Case: 12-50566 Document: 00512199258 Page: 2 Date Filed: 04/05/2013 No. 12-50566 The Government argues that appeal of this sentencing issue is moot and, in the alternative, that the criminal history point was properly assigned to Granados’s prior open container traffic offense. Granados has not filed a reply brief and, thus, has not responded to the Government’s mootness argument. The district court sentenced Granados to 15 months of imprisonment with credit for time served in custody since March 24, 2011. This term of imprisonment necessarily expired on or about June 24, 2012. The Department of Homeland Security has confirmed that Granados was removed from the United States on June 30, 2012. For these reasons, Granados’s appeal is moot. See United States v. Rosenbaum-Alanis, 483 F.3d 381, 383 (5th Cir. 2007). Accordingly, the appeal is DISMISSED AS MOOT. 2 Q: Rails 5.2 encrypted credentials not saving When I do bin/rails credentials:edit my editor opens a file like credentials.yml.enc.1234 with default content. After I'm done editing, I hit save, and the console reads New credentials encrypted and saved. After I run bin/rails credentials:edit again, another temp file gets opened (credentials.yml.enc.4321) and the contents are back to default. How can I make the credentials persist? A: If you aren't using vim, you need to add a wait flag to the editor. e.g for atom: EDITOR="atom --wait" credentials:edit I ran into the same thing and found the answer here. A: There is an issue related to this: https://github.com/rails/rails/issues/31286 It's been fixed already in 5.2.0.rc1 A: I had this problem in rails 5.2.0 using textmate as the editor. It turns out the credentials file must be closed after save in order for the changes to persist. /* * Copyright (C) Sony Computer Entertainment America LLC. * All Rights Reserved. */ using System; using System.Collections.Generic; using System.ComponentModel.Composition; using System.Drawing; using System.IO; using System.Linq; using System.Text; using System.Windows.Forms; using System.Xml; using Sce.Atf; using Sce.Atf.Adaptation; using Sce.Atf.Applications; using Sce.Atf.Controls; using Sce.Atf.Controls.PropertyEditing; using Sce.Atf.Dom; using Sce.Sled.Resources; using Sce.Sled.Shared; using Sce.Sled.Shared.Controls; using Sce.Sled.Shared.Document; using Sce.Sled.Shared.Dom; using Sce.Sled.Shared.Plugin; using Sce.Sled.Shared.Services; using Sce.Sled.Shared.Utilities; using Sce.Sled.SyntaxEditor; namespace Sce.Sled { [Export(typeof(IInitializable))] [Export(typeof(ISledDocumentPlugin))] [Export(typeof(ISledFindAndReplaceService))] [Export(typeof(SledFindAndReplaceService))] [PartCreationPolicy(CreationPolicy.Shared)] class SledFindAndReplaceService : IPartImportsSatisfiedNotification, IInitializable, ISledFindAndReplaceService, ISledDocumentPlugin, ICommandClient { [ImportingConstructor] public SledFindAndReplaceService( MainForm mainForm, ICommandService commandService, ISettingsService settingsService, IControlHostService controlHostService) { m_mainForm = mainForm; m_mainForm.Shown += MainFormShown; m_mainForm.FormClosing += MainFormFormClosing; // Register find and replace -> quick find command commandService.RegisterCommand( Command.QuickFind, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceQuickFind, Localization.SledCommandFindReplaceQuickFindComment, Keys.Control \| Keys.F, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register find and replace -> find in files command commandService.RegisterCommand( Command.FindInFiles, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceFindInFiles, Localization.SledCommandFindReplaceFindInFilesComment, Keys.Control \| Keys.Shift \| Keys.F, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register find and replace -> quick replace command commandService.RegisterCommand( Command.QuickReplace, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceQuickReplace, Localization.SledCommandFindReplaceQuickReplaceComment, Keys.Control \| Keys.H, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register find and replace -> replace in files command commandService.RegisterCommand( Command.ReplaceInFiles, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceReplaceInFiles, Localization.SledCommandFindReplaceReplaceInFilesComment, Keys.Control \| Keys.Shift \| Keys.H, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register F3 to repeat the last search [w/o showing the GUI] commandService.RegisterCommand( Command.RepeatLastSearchWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceRepeatLastSearchWithoutGui, Localization.SledCommandFindReplaceRepeatLastSearchWithoutGuiComment, Keys.F3, null, CommandVisibility.None, this); // Register Ctrl+F3 to search for next occurrence of the current selected text [w/o showing the GUI] commandService.RegisterCommand( Command.FindSelectedTextWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceFindNextInstanceOfSelectedTextWithoutGUI, Localization.SledCommandFindReplaceFindNextInstanceOfSelectedTextWithoutGUIComment, Keys.Control \| Keys.F3, null, CommandVisibility.None, this); // Register Shift+F3 to repeat the last search up [w/o showing the GUI] commandService.RegisterCommand( Command.RepeatLastSearchUpWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceRepeatLastSearchUpWithoutGui, Localization.SledCommandFindReplaceRepeatLastSearchUpWithoutGuiComment, Keys.Shift \| Keys.F3, null, CommandVisibility.None, this); // Register Shift+Ctrl+F3 to search for next occurrence up of the current selected text [w/o showing the GUI] commandService.RegisterCommand( Command.FindSelectedTextUpWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator +
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247, 2454, 310, 5189, 13, 253, 985, 14802, 253, 1481, 434, 1899, 13, 1979, 285, 16753, 281, 21684, 326, 253, 2454, 310, 20420, 3531, 2584, 253, 6568, 323, 253, 985, 281, 8749, 352, 15, 187, 20167, 1320, 1128, 510, 2460, 273, 253, 1481, 310, 24337, 285, 27272, 594, 326, 352, 476, 320, 9856, 285, 18301, 715, 271, 4569, 1979, 285, 16753, 15, 21386, 1320, 310, 2684, 10159, 273, 253, 1481, 434, 4328, 285, 4181, 432, 253, 6568, 15, 187, 35012, 318, 1128, 510, 985, 30376, 253, 17754, 941, 715, 247, 4451, 2127, 15, 831, 12425, 1232 ]	Title: Wireless Transducer Data Capture andRetrieval System for AircraftSerial #08/815,026Filing Date: Mar. 14, 1997Patent #5,943,140Issue Date: Aug. 24, 1999Title: Method and Apparatus for Sending andReceiving Facsimile Transmissions Over a Non-TelephonicTransmission SystemSerial #09/143,232Filing Date: Aug. 28, 1998Title: Multifunctional Remote Control Systemfor Audio Recording, Capture, Transmission andPlayback of Full Motion and Still ImagesSerial #09/257,448Filing Date: Feb. 25, 1999Title: Multi-Casting CommunicationProtocols for Simultaneous Transmission toMultiple StationsSerial #09/257,720Filing Date: Feb. 25, 1999Patent #6,392,692Issue Date: May 21, 2002Title: Network Communication Techniquesfor Security Surveillance and Safety SystemSerial #09/257,765Filing Date: Feb. 25, 1999Patent #6,366,311Issue Date: Apr. 02, 2002Title: Record and Playback System for AircraftSerial #09/257,767Filing Date: Feb. 25, 1999Patent #6,246,320Issue Date: Jun. 12, 2001Title: Ground Link With On-Board SecuritySurveillance System for Aircraft and OtherCommercial VehiclesSerial #09/257/769Filing Date: Feb. 25, 1999Title: Ground Based Security Surveillance Systemfor Aircraft and Other Commercial VehiclesSerial #09/257,802Filing Date: Feb. 25, 1999Patent #6,253,064Issue Date: Jun. 26, 2001Title: Terminal Based Traffic Management andSecurity Surveillance System for Aircraft and OtherCommercial VehiclesSerial #09/593,901Filing Date: Jun. 14, 2000Title: Dual Mode CameraSerial #09/594,041Filing Date: Jun. 14, 2000Title: Multimedia Surveillance and MonitoringSystem Including Network ConfigurationSerial #09/687,713Filing Date: Oct. 13, 2000Title: Apparatus and Method of Collectingand Distributing Event Data to StrategicSecurity Personnel and Response VehiclesSerial #09/966,130Filing Date: Sep. 21, 2001Title: Multimedia Network Appliancesfor Security and Surveillance ApplicationsSerial #09/974,337Filing Date: Oct. 10, 2001Title: Networked Personal Security SystemSerial #09/715,783Filing Date: Nov. 17, 2000Title: Multiple Video Display Configurationsand Bandwidth Conservation Scheme forTransmitting Video Over a NetworkSerial #09/716,141Filing Date: Nov. 17, 2000Title: Method and Apparatus forDistributing Digitized Streaming Video Over aNetworkSerial #09/725,368Filing Date: Nov. 29, 2000Title: Multiple Video Display Configurationsand Remote Control of Multiple Video SignalsTransmitted to a Monitoring Station Over a NetworkSerial #09/853,274Filing Date: May 11, 2001Title: Method and Apparatus for Collecting,Sending, Archiving and Retrieving Motion Video andStill Images and Notification of Detected EventsSerial #09/854,033Filing Date: May 11, 2001Title: Portable, Wireless Monitoring andControl Station for Use in Connection With aMulti-Media Surveillance System Having EnhancedNotification FunctionsSerial #09/866,984Filing Date: May 29, 2001Title: Modular Sensor ArraySerial #09/960,126Filing Date: Sep. 21, 2001Title: Method and Apparatus for InterconnectivityBetween Legacy Security Systems and Networked MultimediaSecurity Surveillance SystemSerial #10/134,413Filing Date: Apr. 29, 2002Title: Method for Accessing and Controlling aRemote Camera in a Networked System With MultipleUser Support Capability and Integration to OtherSensor Systems Several companies have developed computer algorithms that are capable of producing a “digital signature” from video images of people's faces. These signatures are much like a fingerprint: they are unique to individuals; they are relatively small so they are efficient; and, they may be used in databases to look up the identity and other data about the person. While other types of biometrics, such as iris scanning, are at best or even more accurate than facial recognition (which has a relatively low error rate; just under 1 percent), facial recognition will probably be accepted more widely because it is not intrusive. Further, it does not require that the user push, insert or click on anything. Companies often do not need to install anything beyond the new software because most already have cameras in place and pictures of employees on file—making it less expensive than iris reading setups. In addition, the relatively small size of the database for a facial profile makes it an attractive technology. One example of a currently available facial recognition software is the Visionics' FaceIt system. The FaceIt software measures a face according to its peaks and valleys—such as the tip of the nose, the depth of the eye sockets—which are known as nodal points. A typical human face has 80 nodal points and precise recognition can be achieved with as few as 14 to 22 utilizing the FaceIt system. Specifically, the FaceIt system concentrates on the inner region of the face, which runs from temple to temple and just over the lip, called the ‘golden triangle.’ This is the most stable because even if facial hair such as a beard is altered, or if the subject changes or adds glasses, changes in weight or ages substantially the ‘golden triangle’ region tends to not be affected, while places such as under chin would be substantially altered. FaceIt plots the relative positions of these points and comes up with a long string of numbers, called a faceprint. Visage Technology of Littleton, Mass., has a slightly different model. Its software compares faces to 128 archetypes it has on record. Faces are then assigned numbers according to how they are similar or different from these models. The Visage Technology has been utilized to date in the identification of criminals, for access control, for transaction security and for identity fraud prevention. Most recently, government and aviation officials are poised to begin using facial recognition systems to scan airport terminals for suspected terrorists. Recently, Visionics has teamed up with a domestic airline to demonstrate a conceptual boarding system that will use FaceIt to facilitate the rapid boarding of the airline's frequent flyers. In the past, law enforcement officials often have no more than a facial image to link a suspect to a particular crime or previous event. Up to now, database searches were limited to textual entries (i.e., name, social security number, birth date, etc.), leaving room for error and oversight. By conducting searches against facial images, the facial recognition technology permits rapid review of information and quickly generated results, with the ability to check literally millions of records for possible matches, and then automatically and reliably verifying the identity of a suspect. The facial recognition technology has several advantages over other biometric systems. For example, with facial recognition technology a person can be identified at a distance or in a crowd. The technology has the capability of capturing a face in the field of view, extract the face from the background data and compare it against a database. The system permits the creation of watch lists or the like. This could include, for example, known shoplifters, terrorists or criminals, as well as frequent customers, VIP's, expected visitors or individuals generally classified as friends or foes. The system can be used at airports, casinos, public buildings, schools, subways, colleges, factories, business facilities, housing complexes, residences and the like. The system also is useful in transaction modes. Customers are used to being verified or being recognized by their face at retail locations by providing merchants with a driver's license or other form of photo ID. In sharp contrast to today's widely used signature verification process, which is highly unreliable and cannot be accurately determined by unskilled and untrained clerks, face recognition makes verification reliable, automatic and fast. In banking, facial recognition technology can adapt to already installed ATM cameras for recognizing and verifying customer identities so the financial transaction can be quickly and effortlessly conducted. Such technology can replace reliance on alphanumeric PINs to identify and authenticate a user. Face recognition is the only biometric that can be used in two modalities—logon and continuous monitoring. An example of logon modality is use as a perimeter defense mechanism, where an authorized individual gains entry to a network or session after a one-time logon process. This is the typical mode for all biometric systems. In addition, face recognition supports a continuous monitoring mode where persons are continuously authenticated for ensuring that at all times the individual in front of the computer or handheld device continues to be the same authorized person who logged in. Currently available technology focuses on the following aspects of facial recognition: Detection—When the system is attached to a video surveillance system, the recognition software searches the field of view of a video camera for faces. If there is a face in the view, it is detected within a fraction of a second. A multi-scale algorithm is used to search for faces in low resolution. The system switches to a high-resolution search only after a head-like shape is detected. Alignment—Once a face is detected, the system determines the head's position, size and pose to assure that the face is appropriately turned toward the camera for the system to register it. Normalization—The image of the head is scaled and rotated so that it can be registered and mapped into an appropriate size and pose. Normalization is performed regardless of the head's location and distance from the camera. Representation—The system translates the facial data into a unique code. This coding process
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Vascular endothelial growth factor (VEGF)-A has been identified as the predominant tumor angiogenesis factor in the majority of human and experimental murine cancers ([@bib2]), acting via VEGF receptor (VEGFR)-1 and VEGFR-2. Recent studies in mouse tumor models, however, have suggested that some types of malignant tumors also induce the formation of lymphatic vessels (lymphangiogenesis), and that this process promotes tumor spread to regional lymph nodes ([@bib3]--[@bib5]). Moreover, tumor lymphangiogenesis has been identified as a novel prognostic factor for determining the risk for human cutaneous melanomas to become metastatic ([@bib6]). In contrast to the detailed characterization of the molecular mechanisms that control (blood vascular) angiogenesis, the mechanisms underlying the pathologic growth and function of the lymphatic vascular system have remained poorly understood. Thus far, VEGF-C and VEGF-D are the only known lymphangiogenesis factors---acting predominantly through activation of VEGFR-3---which is expressed by lymphatic endothelium in vivo and in vitro ([@bib7]). Several studies in animal tumor models have provided direct experimental evidence that increased levels of VEGF-C or VEGF-D promote tumor lymphangiogenesis and tumor spread via the lymphatic vessels to regional lymph nodes. Furthermore, these effects can be suppressed by blocking VEGFR-3 signaling ([@bib3]--[@bib5], [@bib8]--[@bib10]). Other factors, however, are likely to be involved in mediating tumor lymphangiogenesis and metastasis to the lymph nodes ([@bib11]). Generally, VEGF-A has been considered to only promote (blood vascular) angiogenesis; however, recent work from several laboratories revealed that VEGF-A promotes human lymphatic endothelial cell proliferation and migration in vitro ([@bib12]--[@bib15]), and that lymphatic endothelium expresses VEGFR-2 in situ and in vitro ([@bib12], [@bib13], [@bib16]--[@bib18]). Moreover, intradermal injection of mice with an adenoviral vector engineered to express mouse VEGF-A, but not with adenoviral human VEGF-A ([@bib18]), resulted in the production of enlarged, proliferating lymphatic vessels ([@bib16]). Our recent work has shown that chronic transgenic delivery of VEGF-A to mouse skin promoted lymphangiogenesis associated with chronic skin inflammation ([@bib19]) and with cutaneous tissue repair ([@bib13]). To investigate whether VEGF-A also might be involved in mediating tumor lymphangiogenesis and metastasis to the lymph node, we generated a new transgenic mouse model to target expression of GFP to normal and malignant epidermal keratinocytes. GFP expression was controlled by a keratin 14 (K14) promoter-driven transgene cassette. This model enables the sensitive detection and quantification of lymph node metastasis during experimental, multi-step skin carcinogenesis. We then crossed these mice with our previously established K14/VEGF-A transgenic mice ([@bib20], [@bib21]), and subjected the offspring, which produce fluorescent keratinocytes in the skin that also overexpress VEGF-A, to a chemically induced, multi-step skin carcinogenesis regimen ([@bib22], [@bib23]). We found that targeted overexpression of VEGF-A potently induced tumor lymphangiogenesis in cutaneous squamous cell carcinoma (SCC) and promoted tumor metastasis to sentinel lymph nodes. Importantly, VEGF-A--expressing tumor cells maintained their lymphangiogenic activity after metastasis to lymph nodes. Surprisingly, VEGF-A--overexpressing cutaneous SCC induced lymphangiogenesis in sentinel lymph nodes, even before the tumors had metastasized to these tissues. Together, these results identify VEGF-A as a novel tumor lymphangiogenesis factor. They also indicate that VEGF-A--induced lymph node lymphangiogenesis promotes metastasis, and therefore, is an important target for the treatment of advanced cancer and the prevention of metastasis. RESULTS ======= Transgenic expression of GFP in the skin enables detection and quantification of SCC metastasis to lymph nodes -------------------------------------------------------------------------------------------------------------- To facilitate detection and quantification of skin cancer metastases, we created a transgenic mouse model to selectively express GFP in epidermal keratinocytes, using a K14 promoter cassette ([Fig. 1](#fig1){ref-type="fig"} A). Three transgenic founder lines expressed high levels of GFP in the skin; targeted expression of the K14/GFP transgene in the basal epidermal keratinocyte layer and in outer root sheath keratinocytes of hair follicles was confirmed by fluorescence microscopy ([Fig. 1](#fig1){ref-type="fig"} B). Induction of epidermal hyperplasia by topical application of PMA to the ear skin of transgenic mice resulted in strong GFP expression throughout the hyperplastic epidermis at 1 and 4 d afterward ([Fig. 1](#fig1){ref-type="fig"} C, D). ![K14/GFP transgenic mice provide a reliable new model for the detection of skin cancer metastases. (A) Schematic representation of the K14-GFP transgenic construct. A 720-bp enhanced GFP (EGFP) cDNA fragment was ligated to the BamHI restriction site of the keratin 14 promoter cassette. (B) Targeted expression of the K14/GFP transgene in the basal epidermal keratinocyte layer and in outer root sheath keratinocytes of hair follicles was confirmed by fluorescence microscopy (green). (C and D) Induction of epidermal hyperplasia by topical application of PMA resulted in strong GFP expression throughout the epidermis. Nuclei are labeled blue (Hoechst stain). (E and F) High levels of GFP expression (green) were maintained in tumor cells of papillomas (E) and of SCC (F) induced by the chemical skin carcinogenesis regimen. Immunostains for the panvascular marker CD31 (E; red) revealed tumor-associated angiogenesis, whereas immunostains for the lymphatic-specific marker LYVE-1 (F; red; arrowheads) demonstrated lymphangiogenesis in close association with tumor cells at the advancing tumor edge. (G and H) Metastatic tumor cells in sentinel lymph nodes of K14/GFP transgenic mice maintained high levels of GFP expression, enabling simple detection of lymph node metastasis by fluorescence microscopy (G, green) and quantification of GFP-positive and CD45-negative metastatic tumor cells (66.2% of all cells in this representative case) by FACS analysis of single cell suspensions (H). Bars, 100 μm (B--F), 500 μm (G).](20041896f1){#fig1} To investigate whether GFP expression also was maintained during the successive stages of multi-step skin carcinogenesis and metastasis, the K14/GFP transgenic line that expressed the highest level of GFP was subjected to a standard 7,12-dimethylbenzanthracene (DMBA)/PMA chemical skin carcinogenesis regimen. This involved a single dose of DMBA to initiate tumor formation, followed by 20 weekly applications of the tumor promoter PMA. High levels of GFP expression were detected in all of the cells of early benign papillomas that already displayed marked tumor angiogenesis, as detected by stains for the vascular marker CD31, adjacent to the GFP-expressing tumor cells ([Fig. 1](#fig1){ref-type="fig"} E). Similarly, SCC cells maintained strong GFP expression, and immunostains for the lymphatic-specific marker lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) demonstrated lymphangiogenesis in close association with tumor cells at the advancing tumor edge ([Fig. 1](#fig1){ref-type="fig"} F). Importantly, metastatic tumor cells in sentinel lymph nodes of K14/GFP transgenic mice also maintained strong GFP expression, enabling the simple detection of metastasis to the lymph node by fluorescence microscopy ([Fig. 1](#fig1){ref-type="fig"} G). We investigated whether the extent of metastasis to the lymph node might be quantified by flow cytometry analysis of homogenized lymph nodes. GFP-positive/CD45-negative tumor cells were easily detectable and represented up to ∼66.2% of all sorted lymph node cells ([Fig. 1](#fig1){ref-type="fig"} H). Together, these results established the K14/GFP transgenic model as a suitable model for comparative studies of skin cancer metastasis. Accelerated and increased skin carcinogenesis in VEGF-A transgenic mice ----------------------------------------------------------------------- To investigate the effects of VEGF-A on tumor progression and metastasis, we crossed our line of K14/GFP mice that expressed the highest level of GFP with previously established and characterized heterozygous K14/VEGF-A transgenic mice ([@bib20]). This led to the establishment of K14/GFP and K14/GFP/VEGF-A transgenic mice. These mice were then subjected to the skin carcinogenesis regimen described above. VEGF-A transgenic mice showed accelerated formation of skin papillomas, with an average latency period of 6 wk after the first PMA application, as compared with 12 wk for wild-type mice ([Fig. 2](#fig2){ref-type="fig"} A). By 7 wk, 100% of VEGF-A transgenic mice had developed papillomas, whereas none of the wild-type mice had developed any visible tumor at this time point ([Fig. 2](#fig2){ref-type="fig"} A). The number of papillomas also was increased dramatically in VEGF-A transgenic mice. After 20 wk of PMA treatment, VEGF-A overexpression resulted in the formation of more than 40 papillomas per mouse, as compared with less than 7 papillomas that formed, on the average, in wild-type mice (P \< 0.001; [Fig. 2](#fig2){ref-type="fig"} B). ![Accelerated and increased skin carcinogenesis in VEGF-A transgenic mice. (A) Accelerated development of skin papillomas in VEGF-A transgenic mice (n = 34; filled squares), as compared with wild-type mice (n = 31; open circles). Incidence is expressed as the percentage of mice with detectable papillomas (\>1 mm) during the 20 wk of topical PMA application. (B) Significant increase in frequency of papilloma formation in VEGF-A transgenic mice, expressed as the average number of papillomas per mouse
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7145, 310, 417, 247, 4086, 873, 275, 8805, 13, 352, 434, 247, 906, 273, 253, 2561, 326, 8599, 441, 326, 253, 5130, 4866, 327, 247, 4422, 3798, 7866, 432, 253, 1669, 1930, 15, 1422, 878, 281, 1239, 625, 327, 5130, 4866, 869, 1336, 13, 3340, 670, 253, 401, 14, 17523, 534, 310, 4623, 275, 436, 1083, 15, 380, 5004, 1386, 310, 326, 604, 368 ]	town of Fuquay-Varina and portions of the town of Holly Springs. References Category:Townships in Wake County, North Carolina Category:Townships in North CarolinaWhy are some prison sentences so long? Magazine Monitor A collection of cultural artefacts Published duration 1 August 2013 image caption After sentencing, the judge told Ariel Castro he was too dangerous to ever be released Kidnapper and rapist Ariel Castro has been sentenced to life without parole plus 1,000 years. What's the point in extending a prison term beyond a person's lifetime, asks Tom Geoghegan. Sentencing is not just about determining how long someone should be behind bars, it also has a symbolic, theatrical function, says Franklin Zimring, a professor of law at the University of California, who has written extensively about deterrents. "In sentencing Bernie Madoff [to 150 years for fraud], what the judge wants to be telling him is 'you are really a bad person.' And for this purpose, the number of years can be endlessly elastic." How much symbolic denunciation plays a part can depend on many things, such as media coverage or the nature of an offence, but the tension between these two radically different functions - the symbolic and practical - is a feature of modern criminal justice systems, he says, and not just in the US. There was a famous case in Spain where a fraudster received a 2,000-year sentence. Parole means the sentence can be adjusted at a later date. But it has been eliminated for life sentences in many parts of the country. Most criminal prosecutions in the US are brought by the state, so there can be huge variations in sentencing. Judges are constrained by a statutory range but, depending on the crime, that could be very broad or have no maximum sentence at all. Fraud against one person can involve multiple crimes like false statements, wire fraud and theft, so consecutive sentences for each charge can fast add up. The same goes for crimes involving a computer, like child pornography, because each image could be a separate count. Minor misdemeanours are more likely to result in concurrent sentences. For victims of crime and their loved ones there is nothing problematic about a very long sentence. Indeed, a sentence that increases with each guilty charge is a way of telling each victim that they matter. Some long sentences are an alternative to the death penalty. Dudley Wayne Kyzer is serving two life terms plus 10,000 years for a triple murder he committed in the 1970s. After four years on death row, he was given a second trial because the death penalty in Alabama was at the time deemed unconstitutional.Q: Material UI Box Border for float-right bootstrap element Using a Material UI Box to show border which consist of a bootstrap element <input type="submit" className="btn btn-primary float-right" value="Send" /> Here is the code sandbox link https://codesandbox.io/s/compassionate-forest-81kn0?file=/src/App.js:490-501 The Send Button appears outside the Box when float-right is used. Send Button appears inside the Box when float-right is removed. How to make it float to right while also making it within the Material UI Box. A: Ciao, you could use style to make this. In your input define a style like: <input style={styles.input} type="submit" className="btn btn-primary" value="Send" /> Then in style set display: "flex" and marginLeft: "auto" in this way: const styles = { input: { display: "flex", marginLeft: "auto" } }; and button will appears in form, floated on right. Here your codesandbox modified. Biomechanical studies of the anterior spinal fixators after corpectomy in pigs. An unstable corpectomy porcine spinal model was created for the testing of anterior spinal fixators including: Kaneda device (KD), combination of Polster-Brinckmann prosthesis and Zielke implant (PBZ), and a new prototype device (CH). These spinal implants were examined in a one above/one below corpectomy model to determine the relative stiffness of each construct and the deformation of the adjacent discs under loading. The results indicated that the relative torsion and flexion stiffness were higher for the tested spines fixed with KD and CH. However, the relative compression stiffness of the tested spines was the same for all devices. The rigidity of the spinal constructs, which were measured around the corpectomy region showed the same tendency as above. However, the stiffness of CH and KD constructs were significantly higher than that of the PBZ construct under flexion and torsion. The difference in deformation of the upper and lower adjacent discs was not obvious among the intact spine and the spinal constructs with different devices. Clinical relevances: The corpectomy model represents a "worst case" scenario of spinal instability. In many conditions, spinal reconstructive surgery can restore axial compressive, torsional, and flexural rigidity to normal levels. These experimental conclusions apply to acute restoration of stability, rather than to rigidity after long-term cyclical loading. These three anterior fixators extended to only one cephalad level and one caudal level beyond the corpectomy defect. The new prototype device (CH) has a stability to the Kaneda device. The superior mechanical strength and simpler operative procedure of the new device provide for a potential clinical advantage in restoration of unstable spinal conditions.2012 IRB Junior World Championship squads The 2012 IRB Junior World Championship was an international rugby union tournament held in South Africa from 4 June until 22 June. The tournament was open to players who were born in or after 1992. This article lists the official squads for the 2012 IRB Junior World Championship in South Africa. Pool A Fiji Fiji's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Sale Sorovaki New Zealand New Zealand's 29-man squad for the 2012 IRB Junior World Championship. Head Coach: Rob Penney Samoa Samoa's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: John Schuster Wales Wales's 30-man squad for the 2012 IRB Junior World Championship. Head Coach: Danny Wilson Pool B England England's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Rob Hunter Ireland Ireland's 29-man squad for the 2012 IRB Junior World Championship. Head Coach: Mike Ruddock Italy Italy's 30-man squad for the 2012 IRB Junior World Championship. Head Coach: Craig Green South Africa South Africa's 31-man squad for the 2012 IRB Junior World Championship. Head Coach: Dawie Theron Pool C Argentina Argentina's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Facundo Soler, Bernardo Urdaneta Velez Australia Australia's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: David Nucifora France France's 31-man squad for the 2012 IRB Junior World Championship. Head Coach: Didier Retiere Scotland Scotland's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Peter Wright References External links 2012Q: Is it a bad idea to put the logo in the top-right corner and the navigation in the top-left? Firstly I would like to say that I don't think there is a concrete rule about where the logo on a website should be – but intuitively I think it should be in the top left at least for continuities sake. Is it bad UX to have the navigation placed before a company logo and why? A: This article might also help: Jakob Nielsen: Horizontal Attention Leans Left Extract: People spent more than twice as much time looking at the left side of the page as they did the right: Left half of screen: 69% of viewing time Right half of screen: 30% of viewing time Simply put: Stick to the conventional layout, because it works perfectly with how people look at Web pages: Keep navigation all the way to the left. This is where people look to find a list of current options. Keep the main content a bit further in from the left. The most important stuff should be showcased between one-third and halfway across the page. This is where users focus their attention the most. Keep secondary content to the right. It won't be seen as much here, but that's okay — not everything can get top billing, and you need a place to put less-important material. A: You have to decide what is more important for a company and then what is more representative for that company's website: the logo or the navigation. The positioning of the logo in the top left corner is not a rule set in stone, it's a result of the research that tells us that the eye movement on a website usually starts from the left side. You need to read more on eye movement patters, especially about the F-pattern which is relevant in this case. The bottom line is that if you
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It's a small entertainment, but at least it's working. You have solar? Not hooked up to the zero point? Very long-sighted of you. Now: watch! Varaha, Vamana, Buddha and Kalki! They flow from their painted stools like liquid and run around the inside of the ring, an effortless, cat-lazy lope. The trick with cat circuses, I have found, is to convince them they are doing it for themselves. And lo! I clap my hands and in perfect unison my cats leap from their ordained orbits clean through the paper hoops. Your applause please, but not for me: for Varaha, Vamana, Buddha and Kalki. Now they run in a circle, hurdling through the hoops. What was that? Is there a lesson in every trick? What do you mean? The spiritual significance of the cats I call to perform? I hadn't thought of that. I don't think cats especially spiritual; quite the reverse; they are the most worldly and sensual of creatures, though the Prophet Mohammed, so it's said, was a great lover of cats and famously cut the sleeve from his robe rather than disturb a cat that had fallen asleep there. Now, on with the story. Where am I going? Don't you know it's a terrible rudeness to interrupt the storyteller? You came here to see the cat circus, not watch some old goondah spin a yarn? You've seen cats leap through paper hoops, what more do you want? Where am I going? Very well then, to Varanasi. No, I am not. It's not just the bodhisofts who go to Varanasi. Here's the deal. I have plenty more tricks in my little ring here on the sand, but to see them you will have to listen to my story and remember, the power may be working but the broadcasters are out. Nothing on your screens tonight. But you'll like this. It's a wedding scene. What is a story without a wedding? Elephants bore me. When I say that I don't mean that I find the pachyderm genus tedious, as if I have some special personal conversational relationship with them and knew all their conversational tics and ploys. Is Ganesh not the best-loved god in our entire profligate pantheon? I mean, simply, that elephants carried me; in a howdah like a small gilt temple through the streets of Delhi. Five elephants, with mahouts; one for my school friend Suresh Hira, one for Vin Johar, one for Syaman and one, my sole spit of defiance in the face of tradition, for Sarasvati, and one for me, Vishnu Nariman Raj, the gnarly groom. Delhi's eternal, monstrous traffic broke around the horde of musicians, drummers, dancers, merry-meeters like water. The traffic news had been reporting me as a major congestion for hours. People stopped and stared, women threw rice, ayahs pointed me out to their finger-sucking grandchildren: _there, there he is, Lord Vishnu goes to his wedding._ The chati mags had been full of little else than the first dynastic Brahmin marriage. My other break with tradition: much of the gaudy I had funded myself through the judicious auctioning of the photo rights to _Gupshup_ magazine. Look here am I, in white sherwani and wrinkle-ankle pants in the very best style, the traditional veil of flowers over my face, gripping my sword with one hand (a ludicrous affectation by Sreem, Delhi's most-sought nute wedding choreographer; who could ever sword-fight from the broad back of an elephant?), with the other gripping white-knuckled to the gold-leaf coping of my swaying howdah. Have I said that riding an elephant is like being on a boat on unstill waters? Does what you glimpse through the cascading marigolds look afraid? Were you expecting someone larger? Negotiations had been protracted and delicate over the winter. Hosts of aeai attorneys circled and clashed around my mother and father, temporarily unified, as they entertained the Misras to a grand vagdana. Lakshmi and I sat blandly, quietly, hands folded neatly in our laps on the cream leather sofa as relatives and relatives passed and greeted and blessed us. We smiled. We nodded. We did not speak, not to our guests, not to each other. In our years together at the Dr Renganathan Brahminical College we had said all that we could say to each other. We sat like an old married couple at a metro stop. At last the hosts of clashing attorney aeais withdrew: a pre-nuptial contract was drafted, a dowry was set. It was a brilliant match; property and ware with water, the very essence of life. Of course the price was high; we were Brahmins. It was no less than the flesh of our flesh and the seed of our loins, for all generations. Way down the list of ticky boxes on Dr Rao's shopping list was one I suspect Lakshmi's parents had tickied blindly. I know my parents had. But it was perhaps the most profound change of all that Dr Rao's nanoworkers worked on us. Our genelines were modified. The traits engineered into us were inheritable. Our children and their children, all our conceivable Nariman-Misras marching into futurity, would be Brahmins, not from the microsurgery of Dr Rao, but from our sperm and eggs. Children, offspring, a line, a dynasty. That was our mutually contracted dowry. A match was made! Let great Delhi rejoice! The janampatri aeais had read the stars for the most auspicious fates, the pandit had made the puja to Ganesh and the joint houses of Nariman and Misra had hired _Gupshup Girls_ , Delhi's biggest and brassiest girl band to sing and flash their thighs for two thousand society guests at our sangeet sandhya. Lakshmi duetted onstage with them. Pop-girli hotpants and belly-top looked disturbing on her as she danced and skipped among the high-heels. Too small, too too young to wed. I was never much of a singer. Mamji and Dadaji had neglected to ticky that box. I boogied down in the golden circle with my classmates. Though I had still two years more at Dr Renganathan College under the tutelage of the invisible Mr Khan, our circle was broken. I was all their imminent futures. At India Gate Sarasvati called her mahout to a halt and slipped from her elephant's back to run and dance among my parade of Baraatis. I had defied tradition by inviting her, she defied it back by coming dressed as a man in sherwani and kohl and huge, ludicrous false Rajput moustache. I watched her leap and whirl, brilliant and vivacious with the dancers and drummers and dance, laughing, with monkey-like Sreem and felt tears in my eyes behind my veil of flowers. She was so brilliant, so lovely, so lithe and free from expectation. At Lodi Gardens the celebrity spotters were five deep. Policemen held them back with a chain of linked lathis. They had seen Rishi Jaitly and Anand Arora and ooh, isn't that Esha Rashore the famous dancer and who is that little man with the very much younger wife; don't you know, it's Narayan Mittal from Mittal Industries. Last and least to them was the seeming child perched high on the back of a painted wedding elephant. A blare of trumpets and a barrage of drums greeted us. Then the smartsilk screens draped around us woke up and filled with the characters and, in a never-before-seen-feat of CG prestidigitation, the cast of _Town and Country_ singing and dancing our wedding song specially written by legendary screen composer A.H. Husayin. They were aeais; singing and dancing were easy for them. There, almost lost among the sari silk and garlands as the bridal party stepped forward to greet us, was Lakshmi. We were swept on a wave of drum beating and brass-tootling to the pavilions arrayed across the well-watered grass like a Mughal invasion. We feasted, we danced, we were sat on our thrones, our feet not touching the ground, and received our guests. I didn't see him. The line was long and the atmosphere in marquee stifling and I was bloated and drowsy from wedding food. I took the hand blindly, bored. I only became attentive when it held mine that moment too long, that quantum too firmly. Shiv. "Brother." I nodded in acknowledgment. "Are you well?" He indicated his suit, the fabric cheap, the cut niggardly, the cufflinks and the jewel at the shirt-throat phoney. A bud get wedding outfit. Tomorrow it would go by phatphat back to the hire shop. "I'll be more suitably dressed when you come to my wedding." "Are you getting married?" "Doesn't everyone?" I
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metadata_.ClearToEmpty(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline const ::std::string& VariantTensorDataProto::metadata() const { // @@protoc_insertion_point(field_get:tensorflow.VariantTensorDataProto.metadata) return metadata_.Get(); } inline void VariantTensorDataProto::set_metadata(const ::std::string& value) { metadata_.Set(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), value, GetArenaNoVirtual()); // @@protoc_insertion_point(field_set:tensorflow.VariantTensorDataProto.metadata) } #if LANG_CXX11 inline void VariantTensorDataProto::set_metadata(::std::string&& value) { metadata_.Set( &::google::protobuf::internal::GetEmptyStringAlreadyInited(), ::std::move(value), GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_rvalue:tensorflow.VariantTensorDataProto.metadata) } #endif inline void VariantTensorDataProto::set_metadata(const char* value) { GOOGLE_DCHECK(value != NULL); metadata_.Set(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), ::std::string(value), GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_char:tensorflow.VariantTensorDataProto.metadata) } inline void VariantTensorDataProto::set_metadata(const void* value, size_t size) { metadata_.Set(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), ::std::string( reinterpret_cast<const char>(value), size), GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_pointer:tensorflow.VariantTensorDataProto.metadata) } inline ::std::string VariantTensorDataProto::mutable_metadata() { // @@protoc_insertion_point(field_mutable:tensorflow.VariantTensorDataProto.metadata) return metadata_.Mutable(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline ::std::string* VariantTensorDataProto::release_metadata() { // @@protoc_insertion_point(field_release:tensorflow.VariantTensorDataProto.metadata) return metadata_.Release(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline ::std::string* VariantTensorDataProto::unsafe_arena_release_metadata() { // @@protoc_insertion_point(field_unsafe_arena_release:tensorflow.VariantTensorDataProto.metadata) GOOGLE_DCHECK(GetArenaNoVirtual() != NULL); return metadata_.UnsafeArenaRelease(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline void VariantTensorDataProto::set_allocated_metadata(::std::string* metadata) { if (metadata != NULL) { } else { } metadata_.SetAllocated(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), metadata, GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_allocated:tensorflow.VariantTensorDataProto.metadata) } inline void VariantTensorDataProto::unsafe_arena_set_allocated_metadata( ::std::string* metadata) { GOOGLE_DCHECK(GetArenaNoVirtual() != NULL); if (metadata != NULL) { } else { } metadata_.UnsafeArenaSetAllocated(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), metadata, GetArenaNoVirtual()); // @@protoc_insertion_point(field_unsafe_arena_set_allocated:tensorflow.VariantTensorDataProto.metadata) } // repeated .tensorflow.TensorProto tensors = 3; inline int VariantTensorDataProto::tensors_size() const { return tensors_.size(); } inline void VariantTensorDataProto::clear_tensors() { tensors_.Clear(); } inline const ::tensorflow::TensorProto& VariantTensorDataProto::tensors(int index) const { // @@protoc_insertion_point(field_get:tensorflow.VariantTensorDataProto.tensors) return tensors_.Get(index); } inline ::tensorflow::TensorProto* VariantTensorDataProto::mutable_tensors(int index) { // @@protoc_insertion_point(field_mutable:tensorflow.VariantTensorDataProto.tensors) return tensors_.Mutable(index); } inline ::tensorflow::TensorProto* VariantTensorDataProto::add_tensors() { // @@protoc_insertion_point(field_add:tensorflow.VariantTensorDataProto.tensors) return tensors_.Add(); } inline ::google::protobuf::RepeatedPtrField< ::tensorflow::TensorProto >* VariantTensorDataProto::mutable_tensors() { // @@protoc_insertion_point(field_mutable_list:tensorflow.VariantTensorDataProto.tensors) return &tensors_; } inline const ::google::protobuf::RepeatedPtrField< ::tensorflow::TensorProto >& VariantTensorDataProto::tensors() const { // @@protoc_insertion_point(field_list:tensorflow.VariantTensorDataProto.tensors) return tensors_; } #ifdef __GNUC__ #pragma GCC diagnostic pop #endif // __GNUC__ #endif // !PROTOBUF_INLINE_NOT_IN_HEADERS // ------------------------------------------------------------------- // @@protoc_insertion_point(namespace_scope) } // namespace tensorflow // @@protoc_insertion_point(global_scope) #endif // PROTOBUF_tensorflow_2fcore_2fframework_2ftensor_2eproto__INCLUDED 1. Introduction {#sec1-ijms-20-04632} =============== The results of decades-long research have shown that the therapeutic use of stem cells brings about significant improvements, even in cases of diseases incurable by other methods. Stem cell research is developing very dynamically. Their regenerative potential is used in medicine. Currently, the wide use of stem cells in therapies of many diseases is awaited with high hopes. Wharton's Jelly is a specialized type of connective tissue located inside the umbilical cord, from which mesenchymal stem cells (WJ-MSCs) can be isolated. WJ-MSCs express all surface markers typical for mesenchymal stem cells \[[@B1-ijms-20-04632]\]. These cells, properly cultured and stimulated, are capable of differentiating towards other types of cells \[[@B2-ijms-20-04632]\]. The publications appearing in recent years show the huge plasticity of WJ-MSCs, which have the ability to differentiate not only towards mesodermal cells, such as cardiomyocytes, but also into cells of ectodermal (neurons) and endodermal (hepatocytes) origin \[[@B3-ijms-20-04632],[@B4-ijms-20-04632]\]. In addition, unlike ESC (Emrbyonic Stem Cells), they do not create ethical problems in scientific research. They have higher proliferation and self-renewal rate compared to somatic stem cells \[[@B4-ijms-20-04632]\]. Wharton's Jelly is an extremely valuable source of stem cells. It has been calculated that up to 4 × 10^5^ stem cells can be isolated from a 15 cm long umbilical cord fragment. WJ-MSCs are also characterized by high subdivision activity. They are well tolerated by the immune system, which favors the possibilities for their use in medicine, both in auto and allogeneic transplants \[[@B5-ijms-20-04632]\]. Chronic ischemia of the lower limbs is a condition in which blood flow through the arteries supplying blood to the legs is restricted. The most common cause of narrowing of the arteries which leads to chronic ischemia of the lower
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1186, 11, 76, 3853, 2727, 95, 3122, 76, 3853, 251, 20547, 187, 187, 31515, 14634, 37013, 33263, 323, 6814, 273, 269, 1028, 375, 24009, 27816, 327, 271, 16644, 3554, 300, 36416, 9548, 37013, 33263, 38768, 1712, 4538, 938, 94, 187, 39423, 7040, 187 ]	, Japan) and transferred onto PVDF membranes (Thermo Fisher Scientific). All samples were purified proteins and ALP containing fucosylated N-glycans was used as a negative control. After blocking with PVDF Blocking Reagent for Can Get Signal (NOF, Tokyo, Japan), the membrane was incubated with FasMab, mouse anti-AFP mAb Clone 2B12, or the anti-ALP mAb (Rockland Immunochemicals). The membrane was washed with TBS containing 0.05% Tween-20 (TBS-T) and then incubated with peroxidase-conjugated secondary antibodies. After washing with TBS-T, the proteins were detected with an ECL kit (GE Healthcare). The conditioned media of wild-type and FUT8-deficient HepG2 cells were condensed and protein concentration was quantified by using a bicinchoninic acid (BCA) protein assay kit (Nacalai tesque, Kyoto, Japan). Twenty micrograms of total protein included there was subjected to 10% SDS-polyacrylamide gel electrophoresis, and then transferred to a PVDF membrane (Millipore, Billerica, MA). After blocking with PBS containing 3% BSA or 5% skim milk, the membrane was incubated with FasMab, mouse anti-AFP mAb Clone 2B12 or biotinylated Aleuria aurantia lectin (AAL; J-Oil Mills). AAL was used for detection of fucosylated proteins contained in the conditioned media. AAL recognizes all types of fucosylation, that is, α1,2-, α1,3-, α1,4, and α1,6-fucose-containing oligosaccharides^[@CR22]^ but it is reported that it preferentially binds to α1,6-fucosylated oligosaccharides^[@CR23]^. The membrane was washed with TBS-T and then incubated with peroxidase-conjugated anti-mouse IgG for western blotting and incubated with avidin-peroxidase conjugates (ABC kit, Vector Laboratories, Burlingame, CA) for AAL blotting. After washing with TBS-T, the protein bands were detected with an ECL kit (Wako, Osaka, Japan). Human serum samples {#Sec16} ------------------- In this study, 25 normal human serum samples were purchased from ProMedDx (Norton, MA, USA), 20 liver disease serum samples were purchased from BioreclamationIVT (Westbury, NY, USA), and 55 AFP-positive HCC serum samples were purchased from Access Biologicals (Vista, CA, USA) and BioreclamationIVT (Westbury, NY, USA). The serum samples purchased from Access Biologicals, ProMedDx and BioreclamationIVT have been collected through obtaining informed consent from each donor and under protocols approved by Independent IRB (Sunrise, FL, USA), New England Independent Review Board (Needham, MA, USA) and Schulman Associates IRB (Cincinnati, OH, USA) respectively. All experimental protocols were approved by the research ethics review committee of Sysmex Corporation in accordance with Ethics Guideline for Clinical Research. The AFP concentration and AFP-L3% of human serum samples were measured using µTAS WAKO AFP-L3^[@CR9]^. The AFP-L3 concentration was determined using the following equation:$$\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\rm{t}}{\rm{o}}{\rm{t}}{\rm{a}}{\rm{l}}\,{\rm{A}}{\rm{F}}{\rm{P}}\,{\rm{c}}{\rm{o}}{\rm{n}}{\rm{c}}{\rm{e}}{\rm{n}}{\rm{t}}{\rm{r}}{\rm{a}}{\rm{t}}{\rm{i}}{\rm{o}}{\rm{n}}\times {\rm{A}}{\rm{F}}{\rm{P}}-{\rm{L}}3{\rm{ \% }}.$$\end{document}$$ Immunoprecipitation and western blot analysis {#Sec17} --------------------------------------------- For immunoprecipitation experiments, 25 μL of protein G sepharose FF (GE Healthcare) was incubated with 10 μg of a goat anti-AFP polyclonal antibody (LifeSpan Biosciences) at RT for 1 h. The resin was washed three times with PBS, and incubated with 200 μL of human serum at 4 °C overnight. After washing five times with PBS, bound proteins were eluted with 50 μL of 0.1 M glycine-HCl (pH 3.0). The solution was neutralized with 5 μL of 1 M Tris-HCl (pH 9.0). Ten microliters of the solution was electrophoresed on 10--20% Tris-glycine gradient gels (ATTO) and transferred onto PVDF membrane (Thermo Fisher Scientific). Western blot procedures were performed as purified proteins described above. Primary antibodies used included FasMab and 2B12. The band intensities were analyzed with ImageJ^[@CR24]^. ELISA {#Sec18} ----- The glycopeptide-binding activity of the FasMab was assessed using antigen-immobilized ELISA. Two micrograms per milliliter of BSA-conjugated fucosylated or non-fucosylated AFP peptides (Fig. [2](#Fig2){ref-type="fig"}) diluted in phosphate buffer (pH 7.5) was coated onto 96-well plates at 4 °C overnight. The wells were washed with PBS-T and blocked with 1% BSA in PBS at RT for 3 h. The plates were then washed and incubated with 125 ng/mL of FasMab diluted in 1% BSA in PBS at RT for 1 h. The wells incubated with FasMab were washed, followed by addition of goat F(ab')~2~ fragment anti-mouse IgG (H + L)-peroxidase (Beckman Coulter, Brea, CA, USA). The enzymatic reaction was conducted using TMB substrate. Optical density was measured at 450 nm using an iMark Microplate Absorbance Reader (Bio-Rad). The measurements were performed in triplicate. All data was plotted using GraphPad Prism 6 software.Figure 2Epitope mapping of FasMab using ELISA. (A) Schematic representation of AFP glycopeptides. Positions of mutated amino acids are shown in red. Blue squares, green circles, and red triangles correspond to N-acetylglucosamine, mannose, and fucose, respectively. (B) Bar graph illustrating the reactivity of FasMab to the different AFP glycopeptides illustrated in (A). Error bars represent the standard deviation. The binding activity of FasMab for entire AFP protein was assessed using sandwich ELISA. FasMab (5 μg/mL) diluted in phosphate buffer (pH 7.5) was coated onto 96-well plates at 4 °C overnight. The wells were washed with PBS-T and blocked with 1% BSA in PBS at RT for 3 h. Then, the plates were incubated with fucosylated AFP, afucosylated AFP, AFP from wild-type or FUT8^−/−^ HepG2 cells diluted in 100 mM 2-Morpholinoethanesulfonic acid (MES) (pH 6.0) and 4 mM Tris (2-calboxyetyl) phosphine chloride (TCEP) at RT for 1 h. The wells were washed and ALP-conjugated 2B12 was added. ALP conjugation to 2B12 was performed using an Alkaline Phosphatase Labeling Kit-SH (DOJINDO, Kumamoto, Japan). After incubation at RT for 1 h, the wells were washed, and ALP substrate was added to the wells. Optical density was measured at 595 nm using a SpectraMax 190 Microplate Reader (Molecular Devices, San Jose, CA, USA). The measurements were performed in triplicate. All data was plotted using GraphPad Prism 6 software. Surface plasmon resonance (SPR) {#Sec19} ------------------------------- Fab fragments of FasMab were prepared using immobilized Papain (Thermo Fisher Scientific) according to the manufacturer's instructions. The interaction between fucosylated AFP and the Fab fragment of FasMab was analyzed by SPR using a Biacore X100 instrument (GE Healthcare). Fucosylated AFP was immobilized onto the surface of a CM5 sensor chip (GE Healthcare) using a standard amine coupling procedure. The kinetic data of the binding of the Fab of FasMab to antigen were obtained by injecting increasing concentrations of antibody into the sensor chip at a flow rate of 30 μL/min. Contact and dissociation time were 180 sec and 600 sec, respectively. The measurements were carried out at 25 °C in 50 mM MES (pH 6.0) 50 mM NaCl, 4 mM TCEP, and 0.005% Tween-20. Data analysis was performed with the Biacore X100 Evaluation software. Association (k~on~) and dissociation (k~off~) rate constants were calculated by a global fitting analysis and stoichiometry of (1:1). The dissociation constant (K~D~) was determined from the ratio of the kinetic rate constants as follows: K~D~ = k~off~/k~on~. Sandwich immunoassay for measurement of fucosylated AFP on an automated chemiluminescence enzyme immunoassay analyzer {#Sec20} ---------------------------------------------------------------------------------------------------------------------
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See the NOTICE file # distributed with this work for additional information # regarding copyright ownership. The SFC licenses this file # to you under the Apache License, Version 2.0 (the # "License"); you may not use this file except in compliance # with the License. You may obtain a copy of the License at # # http://www.apache.org/licenses/LICENSE-2.0 # # Unless required by applicable law or agreed to in writing, # software distributed under the License is distributed on an # "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY # KIND, either express or implied. See the License for the # specific language governing permissions and limitations # under the License. class MouseButton(object): LEFT = 0 MIDDLE = 1 RIGHT = 2 Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses. Our objective was to determine the predictive value of specimen radiography for large core (14-gauge) needle biopsy of noncalcified breast masses. Eighty-four biopsies of 83 breast masses yielded 403 specimens. Specimens showing dense material on specimen radiography were predicted to be diagnostic; specimens showing intermediate- or low-density material were predicted to be nondiagnostic. Specimen radiographic and histopathologic findings were correlated for each specimen using vital dyes to mark individual specimens. Of the 403 specimens, 307 (76%) contained diagnostic material representative of the lesion, with a specific diagnosis achieved for 82 (99%) of 83 lesions (62 benign, 20 malignant). Of the 293 passes containing dense material, 268 (91%) proved to be diagnostic; 11 (18%) of 62 specimens containing only low-density material proved to be diagnostic. Of the 25 (9%) of 293 specimens containing radiographically dense but nondiagnostic material, 18 (72%) showed focal fibrosis and had missed the lesion; 15 (83%) of 18 such specimens were obtained in dense parenchyma. The positive predictive value of specimen radiography was 13 (100%) of 13 in fatty breasts; 77 (96%) of 80 in breasts with minimal scattered fibroglandular elements; 91 (94%) of 97 in heterogeneously dense breasts; and 35 (70%) of 50 in breasts with extremely dense parenchyma. Of the 16 lesions sampled stereotactically, specimen radiography helped assess the inadequacy of initial sampling in three (19%). In six (9%) of 68 sonographically guided biopsies, only one or two specimens could be obtained; specimen radiography helped us predict whether material was adequate for diagnosis. Radiography of core specimens obtained from noncalcified breast masses accurately reveals the adequacy of sampling unless the breast parenchyma is extremely dense. Such immediate assessment can help ensure adequate material from lesions that are difficult to biopsy and can thereby improve the diagnostic yield of large core needle breast biopsy.You are here Talisay Police to Probe Teener’s Death Talisay City PNP authorities are conducting investigation on the mysterious death of a 19-year-old male found in Purok Sigay, Barangay Zone 3, Talisay City around 7:00 a.m. Sunday. The victim was later identified by police authorities, according to Superintendent Adonis Rosales, as Orlando Salazar Jr., whose body was found in a nipa plantation in the area already in a state of decomposition. He sustained a lone hack wound on his back. According to his mother the victim was last seen roaming in the fish port two days before his body was found. Police also alleged that the victim had previous cases of theft in the village and was previously sniffing solvent.*Q: Do any Nikon FX cameras allow square-format shooting with DX lenses? When one uses a Nikon DX (APS-C) camera on an FX camera body, the camera automatically enters a "DX crop mode", using only the center portion of the sensor to match the DX format, as explained on Nikon's web site. The FX format is roughly 36×24mm, while DX is 24×16mm, and it's this smaller size that DX crop mode uses. Notice that the short edge of the FX format is equal to the long edge of DX — and of course the image circle is perfectly round, not oblong. Do any Nikon full-frame cameras allow a "square DX" format, either 24×24mm (with some possible vignetting in the extreme corners) or slightly reduced? A: Square format is not supported, but 5:4 aspect ratio offered by D3, D3s, D800 and D800E is only slightly wider, 30mm. The nice thing is that the viewfinder is electronically masked, so you can compose with good precision. This aspect ratio is not provided on a D700 or D3x. Alternatively, you could always crop in post. Of course, you'll also need to disable Auto DX Crop. The Blyth Hotel Simple yet stylish, the Blyth is contemporary seaside hospitality at its best; designed to be welcoming but informal, giving you the luxury of relaxing into Southwold living. A delightfully refurbished family run hotel just 5 minutes walk from Southwold’s famous colourful beach huts or the town centre. All of our 12 bedrooms with en-suite bath or shower, have been elegantly styled during a recent refurbishment. As a family run business, we offer attention to detail in every way and guarantee you’ll find it hard to leave.Headlines Bruins seek split of home-and-home vs. Sabres by Mike Battaglino / NHL.com SABRES (9-23-3) at BRUINS (23-10-2) TV: MSG-B, NESN Last 10: Buffalo 4-4-2; Boston 7-3-0 Season series: The Buffalo Sabres defeated the Boston Bruins 4-2 on Thursday after trailing 2-1 late in the second period. Boston won the first game, also at Buffalo, 5-2 on Oct. 23, with two third-period goals from defenseman Torey Krug. Big story: Buffalo has won two in a row in regulation for the first time this season; it has not won three in a row in any manner. Of the Sabres' nine wins, three are against the Bruins, Los Angeles Kings and San Jose Sharks (sixth, fourth and seventh in the NHL standings prior to Saturday). "I expect [Boston] to probably be a little upset about the loss," Sabres defenseman Mike Weber told the team website. "I think we've always played them hard and it's always been a hard-fought game. I'm not too worried about anything. It's always better when you're into the game when people are hitting you and you're hitting them back, and you're into the battles in front of the net." Team Scope: Sabres: Buffalo acquired forward Linus Omark in a trade Thursday and will put him to work Saturday. "He'll take a spot in the lineup," interim coach Ted Nolan said Friday, according to the Buffalo News. "I'm not 100 percent sure exactly where we'll put him yet but he'll play tomorrow night." The Sabres are short a forward after Cody Hodgson sustained a wrist injury blocking a shot by Krug in the first period Thursday. Nolan said Hodgson would be out "maybe a week or two or three. I'm not sure." Omark, 26, played one game this season for the Edmonton Oilers, who received a conditional sixth-round draft pick in return. He was fourth in the American Hockey League with 29 points in 29 games for Oklahoma City. "He's getting pretty close," coach Claude Julien told the Boston Herald after practice Friday. "Honestly it's a matter of game-to-game right now. I don't know yet [about the game Saturday], but I wouldn't write him off." McQuaid hasn't played this month because of a lower-body injury reported to be a groin pull, missing eight games (5-3-0). The Bruins could wait until after the three-day Christmas break to give him a little more recovery time. "I hope that's not the case," McQuaid told the Herald. "I want to be back playing as soon as I can. I definitely don't want to be going through that cycle of coming back a little bit too soon [and getting hurt again]. But when I'm ready, I'll be ready. Hopefully that's sooner rather than later." Who's hot: The Sabres have killed 14 penalties in a row; they haven't allowed a power-play goal since Dec. 5. Forward Brian Flynn has three of his season's six points in the past two games. Forward Drew Stafford has three points in four games, including his first goal since Nov. 5. Defenseman Christian Ehrhoff has five points in the past six. … Bruins forward Brad Marchand had two goals Thursday, and defenseman Zdeno Chara had two on Tuesday. Forward David Krejci has 11 points in his past 10 games. Share this!! The NHL uses cookies, web beacons, and other similar technologies. By using NHL websites or other online services, you consent to the practices described in our Privacy Policy and Terms of Service, including our Cookie Policy.Independent UX Consultant & Mobile Special
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253, 987, 1930, 273, 253, 19354, 15, 15682, 281, 46112, 15, 187, 187, 34, 35512, 14, 35, 12586, 46564 ]	for me. Whenever I needed to talk to him, whenever I needed help. Again, he was always patient. He was a good friend. I am very glad that I not only got to know Karry Moore but I can say he was a friend to me and my family and because of our friendship I am a better person. Please remember, that we NEVER know when it all comes to an end… but we all know it will end. Do not waste time with the stupid B.S. that life throws at you. In the end NONE OF IT MATTERS. What matters is family, friendship, relationships and love. I do regret that I didn’t spend more time with him. We talked in the past of visiting each other more but I live in Philly and he lived in Florida and we both ran national companies and we both had families… we had great reasons. And when he got sick, I wanted to visit him but he said that he thought I should wait until he got a little better. Every time I asked, he said he wanted to get a little more healthy before I came and visited with him. I am upset that I didn’t book a flight and just go! Just Google "How To Buy a Car" or YouTube "How To Buy a Car" and what you see on the FIRST page is THIS video (The Original One). This video is from 2007, its HORRIBLE, ITS Filled with lies and misconceptions. The speaker is obviously NOT an Automotive Sales Expert... What seriously disturbs me is that NO ONE is doing anything about this... NO ONE? No OEMs, No Dealer Groups, No Dealerships, No Automotive Managers, No Automotive Sales Consultants... No one. There is this stupid propaganda video LOCKED online and it just sits there without challenge? I am not sure about you but this video offends me, it has always offended me. Because it is so one sided and so filled with mistruths and straight out lies... What is sad is that the PUBLIC sees this as REAL, as the TRUTH. Why...? Because it is on the FIRST page of Google and the First Page of YouTube!!! Most people are NOT subject matter experts. They are going online for some information, some direction and then they stumble into this type of trash... What is SAD is that they actually believe it. And why shouldn't they...? Its not like there are other, more compelling videos that tell the REAL story. So, if you are watching this video or reading this post with distain... DO SOMETHING ABOUT IT! Here are a bunch of ideas of articles, blog posts or VIDEOS you could write, record and POST all over the internet: * How To Buy a Car? * How to Buy a New Car * How to Buy a Used Car * What to expect from Car Dealership * What makes a GREAT Car Dealership * How Do you Choose a specific Car Dealerships These are just some basic ideas. The point is CREATE CONTENT, INFORMATION to the PUBLIC. Stop just thinking the internet is a "Point of Sale" resource... You need to capture people at "Point of Interest" and CULTIVATE the opportunity. If you are as pissed as I am when watching this video... Let me know your thoughts- Have you ever looked at the clock and seen it was the end of your shift and you thought to yourself, “Wow — where did the day go?” Or worse, “Uh oh, I got absolutely nothing done today.” Well, you are not alone; most people in our industry feel the exact same way. Automotive professionals sometimes describe working at a dealership as “chaotic,” “a constant fire drill,” “not organized,” “overwhelming,” “stressful,” etc. A lot of dealerships feel like they are grinding to sell cars, but wonder why they constantly fail to hit their objectives. They are confused why they are not selling as many units as they need to, even though they have their team working bell-to-bell most of the month. There is a logical reason of course: They have no understanding or training when it comes to proper time management. Remember, there are only 86,400 seconds in a day. When they are gone, they are gone. For the most part, most dealerships just “react” versus being “proactive.” You can get up and have a positive attitude and want to work really hard, but if you have no plan, you can’t expect to be tremendously successful. Don’t get me wrong — I am sure you can have some success. It will only be short lived, however, or not at the full magnitude that you are capable. Here is an example: If I said to everyone reading this AutoSuccess article that I am giving away $1,000,000 to anyone who can drive from Houston, Texas to Philadelphia, would you be in? Of course you would be. But here is the catch: You can only use this map that I give you. Are you still in? Of course you are. But there is more to the catch. The map is of the city of San Francisco. Uh, oh. That changes everything, because the rules of the $1,000,000 giveaway is that you have to use this map and only this map. So how in the world are you going to get this easy million dollars? Oh, I know: You can have a great attitude. You can think positively, and you can be happy about the opportunity. Is that going to help you accomplish that goal? No. A positive attitude is great, but it is not enough in this example, and it is not enough in the real world at your dealerships. OK, how about working hard? If you work really hard at looking at this map of San Francisco, maybe you can unlock some secret rout to Philadelphia from Houston? No, you can’t. So, working hard is important, but it is not the sole answer. You need to have a map; you need an internal global positioning system (GPS). You need to begin with the end in mind. Car dealerships are awesome, but they are hectic; there is a lot going on. Plus, it is a month-to-month business. I get it. You need, though, to take control of what you have control of — yourself. We all have multiple roles in our life. We are not just automotive professionals. Some additional roles that you might fall into include: • Parent • Son/daughter • Brother/sister • Manager • Leader • Owner • Trainer • Motivator • Analyst • Friend • Volunteer • Veteran • Paramedic • Athlete • Pet owner • Community activist • Baby Sitter (which can have multiple meanings…) So, now take into account how busy your day is, how hectic a dealership is, how intense our industry is and now add all of the roles you play in life. How are you juggling everything? Are you even trying to juggle or are you neglecting important things? There is a better way. Internationally respected leadership authority Dr. Stephen Covey says that the most effective planning is weekly planning — not monthly or daily. It is truly best to pick a time once a week (my wife and I prefer Friday, after work) and map out the following week. The key is not to overload or “pack” as much as possible into a short amount of time. Rather, you want to identify your priorities — a.k.a. “must do’s” — and schedule them first. This should include your different roles. You want to make sure that you put first things first. Here are some examples: • Showroom appointments • Training sessions (can be from the dealership or on your own) • Phone call and follow-up time • Breaks, lunch, etc. (it is important to refresh yourself and “sharpen the saw”) • Any days off • Clients anniversaries, birthdays or other important dates • Personal friends’/relatives’ anniversaries, birthdays or other important dates • Special time with family (and or friends) • Health appointments (doctors etc…) • Relaxation time If you have any questions about this article or would like some advice on how to create a powerful weekly planning road map, please feel free to call me or e-mail me. Sean V. Bradley is the founder and CEO of Dealer Synergy, a nationally recognized training and consulting company in the automotive industry. He can be contacted at 267-319-6776, or by e-mail at [email protected]. The rules have changed in automotive SEO. In fact, they've changed for the entire search engine optimization world. It's no longer a function of quantity that determines rankings. More content, more links, more social signals - that's fine, but it won't help you as of April 24, 2012, the way it used to. Today is the world of SEO quality over quantity. These changes have been anticipated for some time but only now are they really becoming apparent. Some dealers are dropping in rankings based upon their (or their vendor's) SEO efforts. As a result, others are moving up. Which side of the fence do you want to be on? Here are some best practices to help you get on the right side of the fence. Click to enlarge. A Mercedes-Benz dealership
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He put the gun in his pocket and returned to the kitchen. Quickly he cleaned up all but a few tiny shards of glass and dumped the fragments into a garbage can just outside the kitchen door. He went back to the one bedroom which looked in use. Double-bed with a yellow spread -- neat. A couple of small chairs. A vanity, dresser and mirror, beige carpet wall-to-wall and... Where the carpet came out from under the bed by one of twin night tables, a large irregular stain, faded by much scrubbing. Blood? No time for speculation. He began to open drawers, finding only female garments in the vanity, male in the dresser. He went to one of two closets and discovered an array of dresses and shoes, fine quality. He was headed for the second when he had a strange feeling of presence in the room. He froze in stride and slowly turned his head. His gaze fastened on the doorway. Framed in the center with a curious look of placid watchfulness was Valerie McLean. She was dressed in slacks and a white jersey which followed snugly the lift and thrust of her breasts. She wore tennis sneakers. Though she was rigidly immobile, she leaned on the doorframe with apparent casualness. Slowly he let the gun sink back into his pocket and removed his hand. He didn't know what to say except, "Hello, Valerie." "It took you a long time," she said. "Not so long. A few days." "How you must have worked at it," she said, still unmoving. "And how clever you must have been." "I had luck here and there. Or I might never have found you." "How clever," she said again. "And how foolish." "Foolish?" "Why couldn't you tend to your own silly life and let others live theirs the way they have to live it?" "Have to?" "Have to. We do what we have to do." Her voice broke and trembled on the edge of breaking. "I feel sorry for you," she said. "For me?" She nodded. "And for me, and for -- for everyone." She made no sense at all. "Where were you just now?" he said. "I know the house was empty. Where did you come from?" "In the front door," she said, her voice gaining control. "And before that?" "Does it matter?" "Are you alone?" His hand went back to the pocket. "You don't see anyone else, do you?" "It's the ones I don't see that worry me." "If I wasn't alone, you would have known it before now." "Just the same, we'll look around," he said, and this time the gun came out of his pocket. She looked at the gun with small interest. "How thoughtful to be always prepared." "Just walk ahead of me and make the tour, Valerie." Behind her, he went from room to room. He looked outside, front and back. "Now," he said. "We'll start with the other bedroom and we'll take everything out of the drawers and closets. You'll do the work, I'll watch." With a shrug, she preceded him. As they went from room to room, she silently opened the emptied drawers and closets just as he ordered. Her attitude was stoic, resigned. He found nothing incriminating in any corner of the house. They returned to the living room and he sat down facing her with the gun restored to his pocket. "Well," he said. "I didn't really expect to find the money. But I did expect to find some little thing. It's over, Valerie. Completely over. Why don't you just tell me?" "I never seem to know when a thing is over," she said. "That's my trouble. Would you mind giving me a hint as to what got you started on all this?" "I was watching in the mirror when you opened the suitcase. Very few honest people can get that much cash together." "I see. Very stupid of me. But I was so upset." She laughed without humor. "In a way, I paid you five hundred dollars to hunt me down." "Oh, I'll return it," he said. "But not to you. What happened to Roy Whalen, Valerie?" Her face underwent the first real change. "Don't look so startled. I have most of the facts. He and Marty Bates did it together. With Scofield's help, of course. Isn't that right?" "I only listen." "You don't seem the type for this, Valerie. What are you all about? I'm really curious." "You know what they say about curiosity, don't you?" The question came from another part of the room and the voice which asked it was distinctly male. Clayton Scofield stood in the archway of the dining alcove. The round cold mouth of the .45 in his fist dared Scott to move for his own gun. He didn't. "Oh, thank God!" sighed Valerie. "I thought you'd never get here." "Your call caught me with a customer waiting. I had to lend him some money to get rid of him. He was a very bad risk." She got up and went towards him. "No," he said. "Don't get in my way." She paused. "He's got a gun," she said. "Is that so? Stand up, Daniels. And step away from the chair." He obeyed. "Get the gun, Valerie. Walk around him and reach from behind. That's it." Fingers groped and found the .32. She delivered it and it disappeared in Scofield's pocket. "Sit down again, Daniels," Scofield ordered. "How did you know I was here, Valerie?" asked Scott from the chair. His own voice sounded immensely calm while his palms were fear-damp. "Luck," she said with a wry smile. "I was bored and I had gone for a walk. I was just rounding a corner and there you were getting out of the car. I ducked back and watched until you were out of sight. Then I went in and called Clay. While I was talking to him, I heard the back window crash and I went out the front door." "I told you to stay outside and wait for me," said Scofield. "You were taking a chance." "I wanted to keep him busy," she said. "I was afraid he'd leave." "Well," Scofield said, "this doesn't change anything. It only convinces me he's a very bad boy to have around." "He knows much more than we dreamed," said Valerie. "He knows about Marty. And he knows about Roy, too." "Nonsense!" said Scofield. "If he knew you killed Roy he would have brought the police with him." "Oh God, oh God," she moaned. "He didn't know Roy was dead, just that he helped." "What difference does it make?" snapped Scofield. "He already knew one thing too many." "The police know, too," said Scott in the shocked, near whisper which was all he could muster. "Don't try anything with me, Scofield. They know I'm here and they're watching this house." "Save your breath," said Scofield. "I'm familiar with how the police operate. When they have anything, they move right in and make an arrest. Is that his Ford around the corner, Valerie?" "Yes. The gray one." "Let's have the keys, Daniels." He hesitated. "Come on, come on!" He got up, found the keys and began to walk forward with them. "No you don't," said Scofield. "Throw them. None of your boy-scout ideas will work with me. Just remember that." Scott gave the keys a toss. Scofield caught them neatly in his left hand and dropped them in his pocket. "Back in the chair, Daniels." Scott returned, said quickly, "Listen to me, Scofield. Listen carefully. At thirty-five minutes after ten this morning I called a cop by the name of Hoag, Detective William Hoag. I told him everything I know. He followed me up here. Right at this moment he's out there somewhere, waiting for you to make a move. He had a radio car and he's in touch with headquarters. The smartest thing for you to do is...." "The smart thing for you to do is shut your mouth," said Scofield. "You have a dangerous tendency to make me nervous. You think I came this far just to let a small-time sonofabitch like you wreck everything I've done? Two other flunkies stood between me and a half million. You saw what happened to one of them." Stall, stall! thought Scott. "And where's the other one?" he
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7569, 352, 13, 533, 597, 588, 1900, 1891, 15, 496, 619, 2564, 13, 352, 310, 271, 5667, 15, 733, 5082, 457, 85, 320, 253, 23193, 1293 ]	<!--End of nav.sidebar--> </nav> <!--Page content--> <div id="content"> <!-- navbar --> <nav class="navbar navbar-expand-lg navbar-light bg-light"> <div class="container-fluid"> <button type="button" id="sidebarCollapse" class="btn btn-info"> <i class="fas fa-align-justify"></i> </button> </div> </nav> <!--End of div.row--> <div class="row"> <div class="col-12"> <div class="card shadow mb-5"> <div class="title-holder"> <h1 class="title">Language Use in India</h1> <p class="subtitle">Calculated in the Millions</p> <p class="font">Uncheck labels to recalculate.</p> </div> <div class="card-body"> <div id="pieChart"> </div> </div> <footer> <ul class="footer"> <li><a href="http://www.censusindia.gov.in/Census_Data_2001/Census_Data_Online/Language/Statement5.aspx" target="_blank">Data Source</a></li> <li><a href="www.lisaofalltrades.com" target="_blank">lisaofalltrades.com</a></li> </ul> </footer> </div> </div> </div> <!--End of div.row--> </div> </div> <!--End of div.content--> </div> <!--End of div.wrapper--> <!--Lib <script>--> <!--own <script>--> <script src="js/script.js"></script> </body> </html> I've researched on how to use the d3.schemeCategorry20c it seems there is no problem in the way i used it was wondering what could be the problem. Any help will be so much appreciated. A: Change var color = d3.scaleOrdinal(d3.schemeCategory20c); to var color = d3.scaleOrdinal(d3.schemeCategory10); and error should be gone for you There is no more schemeCategory20c in d3.v5 Pages Meta While I wasn’t initially going to include this film, I was watching TCM the other night, and learned some new information about it that made it a whole new film to me. It’s not that I don’t enjoy the film, but there are other films that I think deserve a little more attention. See, this film is everyone’s favorite film and, to a certain extent, this little piece of information that I learned on TCM is the reason why! 7) It’s A Wonderful Life (Frank Capra, 1946) Inspired by an unsuccessful short story called “The Greatest Gift” by Philip Van Doren in 1939, Frank Capra’s film was released with a great less of a successful response than originally anticipated. While some attribute that to its dark themes or non-linear narrative, it also was going against super patriotic films like Best Years of Our Lives (William Wyler, 1946) , which definitely gave it a run for its money. So how did this film make the jump to becoming one of the most loved films in all Christmas-film-history? Simply put, the answer to that question is copyright issues and television. The film, released in 1946, was guaranteed protection under standard U.S. Copyright Protection laws for 28 years. So when 1974 came around, the film came up for copyright renewal. Within that time period, the film was only allowed to be played with proper permission and through proper dispensations, lest the individuals who wanted to show the film get in trouble for copyright infringement. However, when 1974 rolled around, Republic Pictures, the original copyright holder, dropped the ball and didn’t renew the copyright. This started a media chain reaction that caused the film to become as fundamental to the Christmas world as Apple Pie is to the US image. Long story short, It’s a Wonderful Life became public domain and shown on just about every channel on television during Christmas time for many years. You couldn’t switch a channel without seeing Donna Reed’s face. If it wasn’t for this little “accident” of Republic’s (which was “fixed” a few years later, thus why it doesn’t get played as such a multi-channel orgy as it had previously), this film would not be anywhere near as popular. Joe Dante is one of the nicest and most knowledgeable guys you’ll ever meet in your life. From the first time he ever programmed a festival at the New Beverly in 2008 (discussed here by the inimitable Dennis at Sergio Leone & the Infield Fly Rule), I knew he was one of the “good ‘uns.” Realistically, I had known this since I was a kid, but I reserve judgement on someone’s person until I get a chance to meet them (if I get that good fortune- which is rare- but in LA…it happens). However, Joe is absolutely golden. But I really should’ve known that since this was the man who gave us Matinee (Joe Dante, 1993), a film that has a lightly-disguised William Castle-like character (and I’m a huge Castle fan) and is dedicated to the undying love of cinema. I also should’ve known this since I remember seeing Innerspace (Joe Dante, 1987) with my mom in the theater as a kid and thinking it was one of the coolest movies ever, adoring the Sam Cooke song, and thinking that is this was what movies were about, I wanted to see ALL OF THEM all of the time. And yes, I’m a huge fan of The ‘burbs (Joe Dante, 1989) as well. I was so very pleased to get to see that at the New Beverly a little while ago as well. But, as we are all aware, the erudite Dante made a Christmas film. And it is not just any Christmas film, it is the Christmas film. 5) Gremlins (Joe Dante, 1984) One of my friends is probably the ultimate anti-Christmas-film person. He’s down with the food, but the “happy happy joy joy” stuff and any kind of religiousness? Keep that the hell away from him. It’s just not his style. But he loves Gremlins. He really, truly adores this film like it was going out of style. And considering some of his other favorite directors are Tod Solendz, John Woo and Werner Herzog and he believes that Salo by Pasolini is a staple…this is saying quite a bit. He’s not alone, however. Gremlins is widely considered a classic. And I think it’s generally because not everyone likes Christmas in its Joyful Portrayal. See, every bright room has some dark time, and to many people (myself included) the dark time is, in many ways, a great deal more interesting. In fact, if you were to take a look at the other “classic” Christmas films, they are all a bit dark, which leads me to question why we have so much trouble recognizing that. I mean, to be completely honest, It’s a Wonderful Life (Frank Capra, 1946) is a film about a guy who wants to commit suicide. How cheerful a theme is that around holiday time? Polish Gremlins poster. I love Polish posters. A man I wrote about a few entries earlier, Bob Clark, has dipped into the “dark time” of the Christmas room twice, with Black Christmasand with A Christmas Story (Bob Clark, 1983). While the latter film is more comedic, it has more edge than a straight-up, feel-good comedy. Most of the film centers on the gun that the child-protagonist wants, and how his parents think that it will “shoot his eye out,” not to mention the rest of the dark things that happen to the young members of the cast. Are we supposed to injure children in Christmas films? Heh. Well, maybe in my kinds of Christmas movies. As long as they’re accompanied by the right balance that Clark gives us (which he definitely does, in Christmas Story– if you haven’t seen that one, see it). Gremlins has monsters in it. And lord help me, I’m a sucker for a monster movie. I don’t care what season it is. And, more importantly, it has the significant interplay between human, monster, and sympathy. The things that will always get me. You put those things in a film, and more often than not, I’m YOURS. Then you add humor and a dark view of the holidays??? SOLD!! Gremlins has been on my list for these reasons and always will be. People can try to knock it, but they will always fail. In my mind, it is an essential. It wouldn’t be the holidays without
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22688, 267, 3402, 15, 1723, 13, 253, 1551, 285, 4073, 14221, 497, 671, 3012, 2406, 275, 253, 22688, 267, 685, 275, 253, 18134, 3402, 2470, 3235, 374, 1084, 85, 19, 14, 498, 79, 64, 1967, 81, 49510, 910, 709, 14, 881, 568, 2420, 2536, 329, 5301, 875, 27552, 14, 34, 285, 27552, 14, 35, 858, 417, 921, 667, 1534, 2685, 3910, 13, 3707, 323, 253, 4156, 330, 6764, 2796, 81, 13912, 17, 15, 1762, 10, 285, 812, 4271, 29263, 275, 418, 10172, 35, 2470, 3235, 495, 1084, 85, 20, 14, 498, 79, 64, 1967, 81, 49510, 910, 709, 14, 881, 568, 2420, 2536, 5076, 13, 27552, 14, 34, 285, 27552, 14, 35, 574, 3012, 2406, 4073, 2685, 275, 253, 13235, 3402, 685, 275, 253, 22688, 267, 3402, 15, 3308, 13, 2685, 275, 253, 13235, 3402, 369, 625, 5876, 407, 418, 10172, 35, 685, 326, 275, 253, 22688, 267, 3402, 13, 3907, 273, 253, 3361, 273, 29263, 15, 330, 6764, 275, 253, 29841, 285, 11884, 8099, 497, 2406, 275, 27552, 14, 35, 685, 275, 443, 2267, 13, 534, 812, 5513, 247, 3102, 8847, 273, 418, 10172, 35, 275, 253, 5928, 273, 29263, 15, 187, 187, 3220, 50173, 3545, 12213, 11487, 48908, 14, 34751, 33034, 285, 19713, 1159, 187, 6154, 7040, 187, 187, 37872, 14, 12496, 1363, 275, 27552, 313, 3571, 2673, 574, 642, 1534, 27651, 19147, 285, 512, 1363, 275, 443, 2267, 574, 2622, 27651, 15, 5076, 13, 253, 27651, 19147, 313, 3528, 52, 12667, 21, 285, 16, 263, 21777, 12667, 19, 10, 20845, 281, 320, 625, 21270, 275, 253, 3361, 273, 29263, 313, 23802, 14, 34, 475, 10936, 4556, 27552, 14, 35, 28, 475, 81, 13912, 17, 15, 3071, 481, 844, 1119, 10126, 1534, 3910, 875, 253, 2390, 672, 359, 2783, 27651, 19147, 275, 253, 13235, 285, 16, 263, 22688, 267, 8099, 2796, 81, 13912, 17, 15, 2125, 10, 347, 973, 347, 275, 253, 18134, 285, 16, 263, 11884, 8099, 2796, 81, 13912, 17, 15, 4838, 10, 2470, 2841, 337, 1084, 71, 18, 14, 498, 79, 64, 1967, 81, 49510, 910, 709, 14, 881, 568, 926, 2536, 187, 187, 45, 12695, 39, 2193, 285, 19713, 13369, 14118, 403, 17903, 275, 544, 29153, 577, 1084, 85, 21, 14, 498, 79, 64, 1967, 81, 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253, 10177, 5880, 4197, 407, 418, 10172, 35, 403, 1929, 27, 29307, 90, 273, 22170, 275, 253, 28685, 868, 28, 5141, 273, 19713, 33767 ]	F) was calculated from the rest and stress images using 4D QGS [@b17-cln_70p726] software, version 2012.2. Quantitative MBF Measurements ----------------------------- The studies were processed in batch mode using QPET (Cedars-Sinai, Los Angeles, California) to quantify MBF and CFR. In brief, left ventricle (LV) contours were positioned automatically with an algorithm that determines the LV contours from the summed dynamic images data. The 3-D cylindrical region (1 cm diameter, 2 cm length) for the LV input function was automatically placed in the middle of the valve plane and oriented along the long axis of the heart. Dynamic myocardial samples were obtained from the polar map by analyzing all of the time frames within the fixed LV contour boundaries [@b18-cln_70p726]. A standard 1-tissue compartment model was used to quantify MBF, which includes regional uptake and clearance parameters (K~1~ \[mL/min/g of myocardial tissue\] and k~2~ \[min^−1^\]), blood-to-myocardial spillover fraction and myocardial partial-volume corrections. A previously calibrated ^82^Rb extraction fraction was used to estimate MBF from K~1~ [@b19-cln_70p726]. Stress and rest MBF were computed for each sample in the polar map, and CFR was calculated as the ratio of stress/rest MBF. Four basal slices were not used for flow analysis due to low counts in the membranous septum. MBF in each vascular territory was then obtained by averaging the polar map segments in the regions of the LAD, RCA, and left circumflex artery (LCX), according to the standard 17 segments of the American Heart Association model [@b20-cln_70p726] and corresponding to the anterior, septal, lateral, inferior, and apical walls. Image Interpretation -------------------- Rest and stress uptake images were visually analyzed using a 5-point score (0-normal; 1-mild uptake; 2-moderate; 3-severe and 4-no uptake) for relative myocardial perfusion in 17 segments [@b20-cln_70p726]. We compared the GI-A and GI-B patients considering the anterior and septal walls as segments 1, 2, 7, 8, 13, and 14 and the lateral and inferior walls as segments 3, 4, 5, 6, 9, 10, 11, 12, 15, and 16. Segment 17 was excluded in this analysis. Two experienced nuclear physicians who were blinded to the patient data analyzed the perfusion images. Summed stress scores (SSS), summed rest scores (SRS) and summed difference scores (SDS) were determined. An SSS ≥4 and/or SDS ≥2 were considered perfusion abnormalities. A rest or stress LVEF \<45% was considered to be abnormal. Statistical Analysis -------------------- Quantitative variables were expressed in medians (25%-75% quartile), while qualitative variables were expressed in percentages. Differences in the quantitative variables between GI and GII were verified by t or Mann-Whitney tests conditioned by the normality distribution assumption, which was checked using the Anderson-Darling test and the assumption of homogeneity of variances, which was established by the Levene test. In turn, discrepancies among GI-A, GI-B and GII were verified by ANOVA or Kruskal-Wallis tests, supported by the assumptions of normality and homogeneity of variances. Next, multiple comparisons relative to GI-A vs. GI-B and GI-B vs. GII were performed using the parametric or nonparametric Dunnett test [@b21-cln_70p726]. Comparisons of the anterior or septal wall with the other walls were evaluated using the paired nonparametric Dunnett test [@b22-cln_70p726]. Finally, differences in the qualitative variables were analyzed using the Fisher test. All of the discrepancies were classified as statistically significant considering a significance level at 5%. The calculations were performed using the R package, version 3.1.1. [@b23-cln_70p726]. Ethics ------ All of the procedures that were performed in studies that involved human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors. Informed consent was obtained from all individual participants included in the study. RESULTS ======= Clinical and demographic characteristics ---------------------------------------- The patient demographics are summarized in [Table 1](#t1-cln_70p726){ref-type="table"}. In GI patients, 12 had CAD (32%, GI-A) with 2- or 3-vessel disease in 67%, 1-vessel disease in 25% and a myocardial bridge in 8%. Twenty-six patients (68%, GI-B) had normal coronary arteries or \<70% stenosis and normal ^82^Rb-PET perfusion. The median ages were not significantly different (GI vs. GII, p=1.00; GI-A vs. GI-B vs. GII, p=0.06). The female gender was predominant in all groups. Furthermore, the main clinical risk factors, such as hypertension, dyslipidemia and diabetes, were also not significantly different between the groups. Quantitative MBF Measurements ----------------------------- Global and regional values in GI and GII are summarized in [Table 2](#t2-cln_70p726){ref-type="table"}. The stress flow and CFR were significantly lower in GI than in GII in all of the walls (p\<0.001), whereas the rest flow was lower only in the septal and apical walls (p=0.02 and 0.01, respectively). A comparison of the anterior or septal walls with the other walls in GI revealed that the rest flow, stress flow and CFR were significantly lower in the anterior wall and less so in the septal wall. However, the rest and stress flows were also significantly lower in the septal than in the inferior wall ([Table 2](#t2-cln_70p726){ref-type="table"}). A comparison between GI-A and GI-B did not show any significant flow differences, except for the global CFR (p=0.05) and could identify CAD in LBBB ([Table 3](#t3-cln_70p726){ref-type="table"}). Moreover, GI-A and GI-B had significantly lower stress flow in the anterior wall than in the septal wall. Thus, flow in the anterior wall was more affected by LBBB than that in the septal wall, independent of the presence of CAD. CFR in the apical and lateral walls were lower in GI-B than in GII, which could explain a pattern characteristic of LBBB in the absence of CAD. Myocardial Perfusion 82Rb-PET Imaging and LV function ----------------------------------------------------- Twenty-four patients in GI (63%) had no significant perfusion abnormalities and all patients in GII had normal perfusion. Moreover, the perfusion abnormalities (SSS ≥4 and/or SDS ≥2) tended to be more prevalent in the presence of CAD (GI-A vs. GI-B; p=0.06). We found statistically significant differences between the groups when we considered perfusion abnormalities in the anterior and/or septal walls (p=0.04) as well as in the inferior and/or lateral walls (p=0.003) ([Figure 1](#f1-cln_70p726){ref-type="fig"}). LVEF values and LV cavity volumes are summarized in [Tables 4](#t4-cln_70p726){ref-type="table"} and [5](#t5-cln_70p726){ref-type="table"}. Twenty-five patients in GI (66%) had LV dysfunction at rest and all of the GII subjects had normal LVEF. There were significantly lower rest and stress LVEFs in GI than in GII (p\<0.001), but no significant differences between GI-A and GI-B (p=ns). However, GI-A had a high prevalence of LVEF dysfunction (\<45%) only during stress (p=0.02). DISCUSSION ========== An evolution in cardiovascular imaging with PET-CT systems being incorporated into the clinical setting has been occurring since the early 2000s. This trend is partially driven by the fact that cardiac PET-CT offers a noninvasive method to assess relative myocardial perfusion, LV function, MBF and calcium score (15). The importance and independent prognostic values of MBF and CFR using ^82^Rb-PET, beyond relative myocardial perfusion image interpretation, has already been established. Worse patient outcomes and a higher incidence of cardiac events (death and myocardial infarction) have been demonstrated in cases with global CFR \<2 mL/min/g in patients with normal and abnormal relative myocardial perfusion [@b24-cln_70p726],[@b25-cln_70p726]. Despite the low prevalence of LBBB in the general population [@b26-cln_70p726], several studies have reported its frequent association with heart disease. In the Framingham study, CAD was found in 40% of LBBB patients and was associated with a fourfold increase in the risk of cardiovascular mortality [@b27-cln_70p726]. Dynamic alterations in the cardiac cycle produced by LBBB are known: asynchrony of contraction in the ventricles; reduction of LV diastolic
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342, 247, 4980, 414, 4457, 253, 1461, 1100, 273, 253, 2363, 273, 10532, 15, 187, 187, 817, 795, 510, 10417, 382, 273, 253, 15033, 64, 187, 187, 35, 311, 1950, 2044, 858, 417, 8591, 247, 2675, 10532, 13, 285, 1620, 7558, 281, 513, 594, 15, 8565, 3268, 13, 15066, 13919, 13, 39208, 273, 21245, 13, 354, 1253, 28531, 2864 ]	demands and express them in absolute independence. Liberation was his objective, and liberation itself was a great cause, to free Spanish America from colonial occupation and its peoples from foreign laws. Liberty and equality, these were his pivotal themes, and he made them the foundation of his revolution. He thus advanced beyond those creoles who would have been satisfied with autonomy within the Spanish monarchy and whose commitment to equality was always dubious. He also led with the mind as well as the will. It was Bolívar, the intellectual, the political theorist, who gave Spanish American independence its intellectual underpinning, in works whose style and eloquence resound to this day. Liberty, he said, is 'the only object worth the sacrifice of a man's life', not simply freedom from absolutism but freedom from colonial power. From Montesquieu he inherited a hatred of despotism and a belief in moderate constitutional government, in the separation of powers and the rule of law. But liberty in itself is not the key to his political system. He distrusted theoretical concepts of liberty, and his hatred of tyranny did not lead him to the glorification of anarchy. 'Abstract theories create the pernicious idea of unlimited freedom,' he said, and he was convinced that absolute liberty invariably deteriorated into absolute power. His search for freedom therefore was a search for a mean between the extremes of anarchy and tyranny, between the rights of the individual and the needs of society. This would be secured essentially by the administration of justice and the rule of law, so that the just and weak could live without fear, and merit and virtue could receive their due reward. He believed, with Rousseau, that only the law can be sovereign, and law is the result not of divine or despotic authority but of human will and the sovereignty of the people. Equality too was a right and an objective in Bolívar's project. First, equality of Americans with Spaniards, of Venezuela and Colombia with Spain. This equality was absolute, and was the basis of his argument for independence. Second, equality between Americans. European political theorists wrote for communities of relative social homogeneity and appealed to fairly distinct classes, such as the petty bourgeoisie favoured by Rousseau. Bolívar had no such advantage. He had to begin with more complex human material and to legislate for a society with a special racial formation. Americans, he was never tired of saying, were neither European nor indigenous people but a mixture of Spanish, Africans and Indians. All differ visibly in the colour of their skin, a difference which places upon us an obligation of the greatest importance.' This obligation was to correct the disparity imposed by nature and inheritance, by making men equal before the law and the constitution. 'Men are born with equal rights to share the benefits of society,' he observed, but obviously they do not possess equal talents, virtue, intelligence and strength. This physical, moral and intellectual inequality must be corrected by laws, so that the individual may enjoy political and social equality; thus by education and other opportunities an individual may gain the equality denied him by nature. It was Bolívar's opinion that 'the fundamental basis of our political system turns directly and exclusively upon the establishment and practice of equality in Venezuela'. And he explicitly denied that this was inspired by France or North America, where in his view equality had not been a political dogma, a debatable opinion probably influenced by his determination to produce American solutions for American problems. The logic of his own principles led him to conclude that the greater the social inequality, the greater the need for legal equality. Among the practical steps which he envisaged was the extension of free public education to all the people and particular reforms for those sectors who were especially disadvantaged, such as the landless and the slaves. Liberty and equality, these were the essential objectives. But how could they be realized without sacrificing security, property and stability, those other rights by which society protected the persons and possessions of its citizens? In principle Bolívar was a democrat and he believed that government should be responsible to the people. As he moved into Venezuela to confront the rebellion of Páez in December 1826 he warned the people against warlords and their parties: 'Only the majority is sovereign; he who takes the place of the people is a tyrant and his power is usurpation.' But Bolívar was not such an idealist as to imagine that America was ready for pure democracy, or that the law could instantly annul inequalities of nature and society. Until our people acquire the political virtues of our brothers in North America, he said, I fear that popular systems of government, far from helping us, will be our ruin. He had no confidence in the people en masse as they came out of the colonial system; they had to be re–educated under the tutelage of a strong executive before they could be fit for liberty. Meanwhile: 'Complete liberty and absolute democracy are but reefs upon which all republican hopes have foundered.' He spent his whole political career developing his principles and applying them to American conditions in his own version of the age of revolution. 'His principle was not to expect too much from a people who unhappily might still be considered little better than a nation of slaves, to give them no more power than they were able to direct, and to have wholesome checks on those who held such power.' Until they were educated into political society his solution lay not in a federal system, which he consistently opposed, nor in monarchy, of which he was accused, but in his Bolivian Constitution, though even about this he was more diffident than is often supposed. Bolívar's revolution did not resemble revolutionary movements in Europe or the Atlantic world. These reflected conditions and claims which were appropriate to themselves but had only limited application to the political, social and economic problems of America. The European Enlightenment and its liberal aftermath, well known to Bolívar, were too self–absorbed to offer political ideas or services to colonial peoples. The economic interests of industrial Europe, being those of a metropolis, involved some opportunities for primary producers but also disadvantages, and if industrialization was a medium of social change in western Europe, it played no such role in early nineteenth–century Spanish America, whose concern was to strengthen the traditional export sector – and with it the landed oligarchy – in order to import manufactures made by others. For these reasons Bolívar, who in many respects had a deep affinity with the age of revolution, could not imitate its intellectual and political leaders, even had he wished to do so. While the Enlightenment confirmed his attachment to reason and inspired his struggle for liberty and equality, he had to employ his own intellectual resources to fashion a theory of colonial emancipation, and then to find the appropriate limits for liberty and equality, and in the process we can see traces of enlightened absolutism as well as democratic revolution. Democratic forms in Europe and North America evoked his respect, but he insisted on writing his own constitutions, designed to conform to Spanish American conditions, not to outside models. These conditions, especially in the post–war period, when social and racial divisions, lack of consensus and absence of political traditions placed liberal constitutions under severe strain and brought the new republics to the edge of anarchy, caused serious problems for Bolívar. Now we see the realistic Bolívar – his democratic ideals tempered by experience of popular protest, race conflict, and elite factionalism – the man who declared Spanish America to be ungovernable. The Bolivarian model of government, designed around the life presidency, appealed to the military but otherwise made few friends: it excluded too many vested interests from political life and decisions to gain wide acceptance. The civilian elites preferred more liberal constitutions, though even these and their authors were affected by that bias towards authority and centralism that was a feature of the republican as it had been of the colonial state. Most Venezuelan constitutions allowed the president extraordinary powers of intervention in time of crisis or rebellion, and most defined the political nation in the narrowest of terms, establishing property and literacy qualifications for those entitled to stand for election and even to vote. Bolívar had nothing to be ashamed of in any comparison of his constitutional principles with those of his liberal enemies. Historians have suggested that he abandoned the search for liberty, or at least postponed it in favour of order and security. But the evidence shows that his principles in 1828–30 were not basically different from those he had developed from 1812 onwards, that his insistence on liberty and equality was always accompanied by a search for strong government. Bolívar conceived the American revolution as more than a fight for political independence. He also thought of it as a social movement, which would improve as well as liberate, and would respond to both the radical and liberal demands of the age. For him a free government had to be an active government, moving beyond dispensing privileges and patronage into the more positive work of giving Americans a better life. Strong government was essential for the new states if they were to impose reforms, an incomprehensible synthesis for the liberals of his day, but better understood by later generations of Latin Americans. Many of them came to believe that powerful presidential government and one–party states were suitable, or at least inevitable, constitutional forms for new nations in formation. Bolivarian absolutism, therefore, was not an end in itself. The bias towards strong government, in the interests of reform as well as of order, and as a necessary framework for post–colonial development, was a quality rather than a flaw in Bolívar's policy, and endows him with a modernity beyond the confines of the age of revolution. ## _The Realist of the Revolution_ Bolívar did not promote a social revolution, and never claimed to do so. Land distribution, racial equality, abolition of slavery, pro–Indian decre
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It is not available as a supplement, to my knowledge. The best dietary source is a Japanese fermented soy product called natto, which is famous for its vile flavor. Other dietary sources include soy products and wheat germ. And yes, it is found at high concentrations in semen. Read more Alternative to Chemotherapy and Radiation Dr M Rigdon Lentz (an American) runs a German clinic with a unique cancer treatment. Cancer cells protect themselves from attack by the body’s immune system by spitting out many “false target” molecules that attract killer T cells in the blood and distract them from the real culprit, the cancer cells themselves. Lentz’s procedure involves filtering these decoy molecules from the blood. Often this is sufficient to initiate a fierce immune assault on the tumors, which flare up hot and red. Lentz described some dramatic cures. He reports major regression of tumors in 70% of his patients, despite the fact that most of them have been treated previously with chemo and/or radiation and traditional oncology has given up on them. Read more DRACO – kills all virus-infected cells Todd Rider of MIT is quietly witty on-stage and charmingly self-effacing, but his program is radically ambitious. He wants to cure all infectious disease. DRACO is an acronym for Double-stranded RNA-Activated Caspase Oligomizer. Start with the observation that single strands of RNA are used in all cells, but double-stranded RNA is found only in cells infected by viruses. The DrACO molecule has three parts: One part speaks to the body’s “mail system” that looks at address tags on a molecule, and uses those to send them to a particular cell. DRACO molecules are targeted to a particular kind of cell that is infected. Part two is a detector of double-stranded RNA. And if dsRNA is found, then part three is activated: molecular signals that trigger cell death. The bottom line is that DRACO molecules can find cells that are infected with any virus, distinguish them from uninfected cells, and selectively signal the cell to destroy itself. It’s been tested in test tubes and in mice it cures, for example, the flu. Rider’s lab is producing only tiny quantities of DRACO at present, but by year’s end he hopes to ramp up production for much wider testing. Read more RTEs = Retro Transposable Elements Half of our DNA consists of repetitious stretches of DNA that never get translated into proteins. This was once referred to as “junk DNA” or even “parasitic DNA”, but it probably plays an important role in evolution. One piece of evidence for this is that RTEs of recent origin (those unique to primates) are a lot more active and mobile. They’re the part of us that is presently evolving. John Sedivy of Brown University reported that senescent cells – cells that have depleted their telomeres – are far more likely to have active RTE’s. These DNA segments make RNA copies of themselves which can then be “retro-transcribed” back into the chromosome, with disruptive consequences. (Transcription = DNA→RNA, part of the path by which chromosomes control the cell; Retro-transcription = RNA→DNA, an unusual and often pathological process) Read more Retinoic Acid promotes regeneration of damaged tissue Retinoic Acid is an ingredient in prescription cremes which treat acne and also aging skin. Malcolm Maden from University of Florida reported that retinoic acid promotes regeneration generally. Read more Genetic therapy is much advanced Frank Church of Harvard reported on the state of the art in gene therapy. Fourteen years ago, the first gene transplant experiments resulted in death of a (very sick) teen patient, and set the field back several years. But advances in the interim make it possible now to insert a gene safely into a large number of cells of a lilving body, and target them to a precisely specified position on a chosen chromosome. This is done using CRISPRs, which are short stretches of RNA with a distinctive palindromic pattern, used by viruses to find the right place to insert themselves into a host genome.Read about CRISPRRead about Gene Therapy Plasticity of the brain Jean Hébert of Einstein Medical Center in New York is working to inject neural stem cells into the brain, to grow new nerves. This might seem like an impossible challenge. Nerve cells regenerate at a rate lower than any other cell type in the body, and even if we got them to regrow, how would they come to carry the knowledge and skills that we have acquired during a lifetime? Hébert reports a hopeful and amazing fact: In patients with brain tumors that destroy function in one part of the brain, another part picks up the function smoothly and without noticeable disruption. This has been noted with fMRI studies based on Boca’s area, which houses language. Read more Growing a liver on a lymph node There is a long waiting list for liver transplants. In the US, 90% of patients with liver failure will die before they get a transplant. Some have proposed transplanting livers from pigs. Eric Lagasse of Wake Forest Inst for regenerative medicine has another idea. He has had success growing new livers from stem cells in the patient’s body. Liver progenitor cells are implanted in a lymph node, which seems to provide a favorable environment for growth. In mouse models, 70% are able to grow a functional liver “ectopically”, meaning in a part of the body where it does not belong.Read more One of the oldest and best-established theories of aging holds that we age because of oxidative damage. In the classic version, the body exploits high-energy chemistry based on oxidation for an energy supply at the cellular level, but this involves constant exposure to these high-energy species and the free radicals that are their by-products, species which can attack sensitive biomolecules. Damage to these molecules accumulates over a lifetime, so the story goes, and makes the body gradually less able to maintain its balance. I’ve argued against the general idea that aging is an accumulation of damage, because of evidence that it is an active process, closely regulated like everything else about life. But new to me this week is a version of the theory by Spanish physiologist Gustavo Barja, in which some of the same chemistry is described as an active program of self-destruction. Barja argues that the process of burning fuel to produce energy can be extremely clean or it can be rather dirty. It is the “leakage” of free radicals during the process that causes the damage of aging, and this leakage can be quite fast, or it can be almost nil. Leakage is tightly-regulated in a way that determines life span. This is a unique lens through which to view aging. What does it help us to understand? An old and (I believe) discredited view of aging is that the body ages the same way a tool rusts or a car wears out over time – because damage accumulates with wear and exposure to corrosion. The best-established version of this theory is based on damage in the cellular energy factories, the mitochondria, and it is called the Mitochondrial Free Radical Theory of Aging, MFRTA. I visited last week with a man who has devoted his career to studying the chemistry of mitochondria, and he has come to believe that indeed mitochondrial chemistry has a lot to do with aging, but this is not just damage that accumulates as a side-effect of the energetic chemistry. He thinks that this damage is purposeful and programmed, and has written an updated version of MFRTA. Everything that you have heard about free radicals, ROS (reactive oxygen species) and anti-oxidants derives from the MFRTA. Mitochondria are tiny energy factories. Hundreds of them in each cell of our body burn sugar and convert the energy to an electrochemical form, analogous to charging a battery. This is the Krebs cycle. The electrochemical energy (in the form ATP) is then used for nerve signals and muscle movements and manufacturing biochemicals – everything for which the body requires energy. Classic MFRTA In the original version of MFRTA theory, there are unavoidable by-products of the highly-energetic chemical reactions that power our bodies. These are free radicals or ROS, and they corrode the body’s delicate chemistry. There are quencher chemicals – antioxidants that help mop up the toxic waste. These include SOD, ubiquinone (coQ10), and glutathione, catalase, and vitamin C. But they are not 100% efficient at preventing damage. It is the buildup of damaged biochemicals that is the root cause of aging. One of the attractive things about the MFRTA is its connection to evolutionary history. Once upon a time, more than a billion years ago, mitochondria were infectious bacteria. They invaded the primitive cells at the time, lived as parasites, and killed the cell with their powerful oxidative toxins. Over a long period of time, the parasites evolved to be friendlier to the host, and the host evolved to exploit the energy products of the parasite. Every eukaryotic cell, including all multi-cellular life today, is descended from this ancient symbiosis. Modern mitochondria are performing in the service of the host cell, and have no will of their own. But they retain the capacity to kill the cell, and in fact can serve as executioners when they are signaled to do so. This is apoptosis, or programmed cell death. Problems with the MFRTA theory include: Anti-oxidants don’t seem to extend life span when fed
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"官方文档地址：https://pandas.pydata.org/pandas-docs/stable/reference/api/pandas.Series.shift.html" ] }, { "cell_type": "code", "execution_count": 14, "metadata": {}, "outputs": [ { "data": { "text/html": [ "<div>\n", "<style scoped>\n", " .dataframe tbody tr th:only-of-type {\n", " vertical-align: middle;\n", " }\n", "\n", " .dataframe tbody tr th {\n", " vertical-align: top;\n", " }\n", "\n", " .dataframe thead th {\n", " text-align: right;\n", " }\n", "</style>\n", "<table border=\"1\" class=\"dataframe\">\n", " <thead>\n", " <tr style=\"text-align: right;\">\n", " <th></th>\n", " <th>bWendu</th>\n", " <th>bWendu</th>\n", " <th>bWendu</th>\n", " </tr>\n", " <tr>\n", " <th>ymd</th>\n", " <th></th>\n", " <th></th>\n", " <th></th>\n", " </tr>\n", " </thead>\n", " <tbody>\n", " <tr>\n", " <td>2017-01-31</td>\n", " <td>3.322581</td>\n", " <td>NaN</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-02-28</td>\n", " <td>7.642857</td>\n", " <td>3.322581</td>\n", " <td>NaN</td>\n", " 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733, 1904, 626, 789, 15, 7214, 670, 2620, 8014, 273, 1110, 20003, 2455, 3047, 253, 657, 727, 1373, 969, 15, 754, 369, 581, 273, 731, 2698, 187, 187, 1909, 253, 8986, 273, 22420, 1253, 47868, 14782, 327, 13, 752, 3589, 626, 4755, 369, 1880, 253, 2862, 5685, 1899, 275, 253, 11053, 48727, 651, 564, 281 ]	though, once the Russians attacked with masses of wide-tracked T-34 tanks backed by hordes of Siberian infantry dressed in warm winter uniforms. Hitler ordered troops to stay in place, regardless of the cost, to prevent a rout. That saved the German army, but it would never get that close to Moscow again. ## Mother Russia Is a Cruel Mistress Invading Russia has never been a good idea, historically. France's Napoleon and Sweden's Charles XII failed miserably, losing their armies. Like his predecessors, Hitler was made overconfident by early victories. The easier alternative is not invading. It is doubtful this would have been a sound strategy. Soviet dictator Joseph Stalin still allowed his staff to plan a possible attack on German-held Poland in the spring of 1942. Such a move was improbable, but not impossible. Focusing on the German invasion itself, we can see that there were things that could have been done differently to better prepare for the campaign. Germany could have put more effort into expanding its auto industry, adding more trucks to its motor pool. Or it could have improved its rail capabilities, making them able to convert track from Russian to German gauge at a faster clip. Operationally, Germany's generals could have narrowed the plan. As originally written, three army groups would have had to take Leningrad, Moscow, Ukraine, Crimea, and the Caucasus, all in one campaign season! And solidify their gains before the winter weather arrived! Planners could not seem to limit their goals to the attainable. While the German army captured some strategic objectives, German strength was stretched too thin in the attempt to take all of them. Perhaps a better move was to forgo Leningrad and concentrate on Moscow and Ukraine. Or fight a slower campaign, moving all three army groups east by three hundred miles, stopping, then riding out the winter while managing a strained, but shorter supply line. The lull would have allowed rail lines to be converted to German gauge for their entire length; then the supply dumps could have been rebuilt. By gambling, Hitler came within twenty miles of taking Moscow. Being less ambitious he could have reaped Moscow as the prize in 1942, avoiding Stalingrad and an overstretched campaign in the Caucasus. This would have been inconsistent with the way Germans fought their wars, favoring the attack and quick pursuit over deliberate advance and supply. German determination and improvisation can only take an army so far when supplies are lacking. # 62 # RONALD REAGAN STARS IN CASABLANCA 1942 By Mike Resnick What if this actor had not played on the world stage? The unproduced play was titled _Everyone_ _Comes to Rick's._ After it failed to find a Broadway producer, it was submitted to Hollywood, where story editor Irene Diamond read it, thought it had possibilities, and recommended that Hal B. Wallis purchase the film rights, which he did for a less-than-munificent $20,000. The title was changed to _Casablanca_ , where the action took place. It starred Humphrey Bogart and Ingrid Bergman, it featured Claude Rains and Paul Henreid, and it had a delicious supporting cast that included Peter Lorre, Sydney Greenstreet, Conrad Veidt, S. Z. Sakall, and Leonid Kinskey. It was rewritten on an almost day-by-day basis by the team of Julius and Philip Epstein, with some additional help from Howard E. Koch, and directed by Michael Curtiz. The film was originally scheduled for release in mid-1943, but it was rushed into distribution, with a world premiere on November 26, 1942, and an official release date of January 23, 1943, to capitalize on the Allies' landing in North Africa. No one at Warner Bros. expected it to do much at the box office or in the awards, which just goes to show how incredibly wrong people can be. _Casablanca_ won the Academy Award for Best Picture, became an instant classic, and has always ranked among the top two or three films every time the American Film Institute ranks its top one hundred films. It made five-foot-seven-inch balding Bogart a romantic lead, as well as the most popular actor in America. Okay, that's what happened. But what might have happened is just as interesting. Humphrey Bogart was not the first actor considered for the role of Rick Blaine. Jack Warner wanted George Raft or James Cagney, and after all, Bogart had only one big hit behind him—the recent _Maltese Falcon—_ and he had never played a romantic lead. But before they signed Bogart, they had in mind yet another Warner's contract player. There's every chance you may have heard of him. On January 7, 1942, Warner Bros.'s Hollywood News Press Service released the following statement: "Ann Sheridan and Ronald Reagan will be teamed by Warner Brothers for the third time in _Casablanca._ " Nothing came of it. But what if Reagan _had_ wound up with the role of Rick Blaine? Yes, he was in the army by then . . . but what if they'd held the movie for him? After all, not a single theatrical producer had been willing to put it onstage, and Bogart's name wasn't yet box office magic. What if the film, made in 1945, was every bit as popular with him in the lead as it was with Bogart? What logically follows? Well, for starters, Reagan moves up the ladder to become Warner's number one romantic lead. But the wild popularity of _Casablanca_ has created a huge demand for his screen services, and he finds himself overwhelmed with offers. His next appearance is the lead in _To Have and Have Not_ , a role that would have gone to Bogart had Reagan not established himself as a romantic star in _Casablanca._ The film is a hit, and suddenly Reagan has his choice of plum roles, roles that would never have been offered to him had _Kings Row_ been the apex of his acting career. He beats out Gregory Peck for the lead in _Gentleman's Agreement_ , actually wins an Oscar after beating relatively unknown Ernest Borgnine for _Marty_ , makes thirty-five films—most of them big-budget, highly publicized ones—between 1946 and his retirement (after starring in his final film, a television remake of _The Last Hurrah_ ) in 1977 _._ At one time, during the war, he thought of working for the Screen Actors Guild when he came home, perhaps even running for an office within the guild. But when he received literally two million accumulated fan letters and fourteen bona fide movie offers, he realized that he couldn't possibly take the time, at least not until he took some of these very choice acting jobs and put some money in the bank. But of course, the more he performed, the more offers came his way, and the more the industry depended on him to keep performing, and he finally realized that no, he was not going to run for president (or any other office) of the Screen Actors Guild. It was two decades later that the policies of Governor Pat Brown and other Democrats so outraged him that for the first time in his life he registered as a Republican. He was working constantly, as he had been since 1945, but he donated some $3 million to Republicans in state and national races. It would be nice to say that he and Bogart traded places, but Bogart was an on-and-off liberal, and his chain-smoking caused his death in January of 1957. So what _did_ happen during the years that Reagan, under different circumstances, might have run for president, not of the Screen Actors Guild, but of the United States of America? Well, there was quite a battle among Republicans, but George H. W. Bush emerged with the 1980 nomination, and beating Jimmy Carter when Iran was holding dozens of hostages and the prime rate topped 21 percent was even easier than it had looked, with the seated president winning only ten states. Bush didn't scare the Ayatollah Khomeini the way a President Reagan would have, and in 1982, the United States invaded Iran, freeing all but five of the hostages (who were killed during the action) and replacing Khomeini with a pro-democracy, pro-America ruler. Bush did not preside over the phenomenal economic recovery and job growth that Reagan would have brought about, but compared to the economy he inherited, he was soon labeled an economic wizard, and of course he won reelection in 1984. It was said that he relaxed from the heavy pressures of his office by watching endless reruns of _Casablanca._ # 63 # KURSK 1943 By Harry Turtledove "My stomach turns over." After Field Marshal Friedrich Paulus surrendered the last ninety thousand starving, freezing Germans in Stalingrad at the end of January 1943, anyone with eyes to see should have understood that Hitler would never beat Stalin on the Eastern Front. (Paulus was promoted to field marshal just before the surrender, to persuade him to shoot himself instead of giving up—no German field marshal had ever surrendered. It didn't work. Only about five thousand of those Germans ever saw the Vaterland again. He was one of them.) As the winter of 1942–1943 wore on, what wasn't obvious was whether the entire German position in the southern USSR would go to
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completely suspended in the universe. You actually feel like you are in space and moving with the organic movements of the universe. The lightness is where I’m no longer in the matrix with you. You’re talking and I’m so free in this entire universe that I can feel the universe and my suspended state. You can feel the current, the neural pathways in your brain in the opposite hemisphere that begins to wake up, that says: oh, oh, I’m God; yes, I’m God. I’m not my emotions or defined by them. You’re introducing two things to the frontal lobe – vibration and light. The frontal lobe is meant to repeat the name of God. That’s what it’s designed for. The frontal lobe is there to keep us constantly in that current of vibration. If you could sustain your lightness and luminosity, the entire matrix of your being will rearrange itself. So when I say to you: if you can feel that currency and really be aware of that and the light at the same time, within three months you’re going to be so grateful to be alive that you’re ready to explode. You’re so grateful that every moment and every cell within your body belongs to the universe. Throughout your whole year, if you truly become grateful, and truly allow – I don’t care if somebody cuts you off, you can go: you stupid bugger. But if you engage into the action, you’ve just created another mirror of reflection that sits in your future. We are at an intensified period of time when if you become grateful, even if you simply say: I hate my job! Be grateful; because that will get you another job. But the more you loathe your job, the deeper you’re going to sink. The more grateful you are for everything, the more you will get uplifted. Whatever you think you are in charge of, just realize you’re in charge of nothing! Zero! This is a time where you might think you can think your way out of it and you cannot. But you can lift your way out of it. You need to fly. And if you fly throughout this entire year, you’ll pull yourself predominantly out of this matrix because energetically this is what the universe is all about. Let this whole personality identity step aside and really TRUST big time. Say: I’m going to be fine. It’s going to be good. God loves me. God knows where I am. God has my address. God has my email address. God has my phone number. I am in his directory. He knows who I am; knows where I live. The reality: that is that shift in the lightness. God knows every moment, every second, every burp, every fart, every moment, God knows. You are so much more than who you are today. This blog is an excerpt from the Pathway to Consciousness event in January 2017 in Toronto, Canada. ]]>[email protected] (Bart Smit)BlogWed, 31 May 2017 01:00:00 +0000Trump and the January 2017 Women's March - The currency of Freedom!https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/66-trump-and-the-january-2017-women-march https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/66-trump-and-the-january-2017-women-march You know it’s going to be loud and noisy. But it’s all right; it’s what needs to happen. Women are extraordinary when it comes to change. Are women uniting humanity? Absolutely. Women are the ones who give birth to children. They create the next generation. That many women who demonstrated without someone like Trump stopping it or trying to do a curfew – for that to have happened is extraordinary. That demonstration is the beginning of the wave that will create change in the world. Imagine there are reptilian races all fighting for power. Do I think this is a good thing? Absolutely. Kill each other. Knock yourselves out. Let the world wake up to recognizing that this kind of behavior that has existed for centuries….Donald Trump and someone like Hitler – there is no difference. They’re exactly the same. One had the ability to kill people and the other is in the process of creating chaos. He is using the same methodology of creating fear. Exactly what Hitler did. But the world didn’t stop Hitler. So, do I think this is a massive opportunity for Consciousness to rise? Absolutely. When you listen to someone like Trump and what he does, if you have great faith in the universe, he will last one day less. The more you judge him, the more you observe and absorb, process, and have an opinion, the longer he stays in power. Why does your boss at work have power? Because you gave him power. Why does anybody have power? Because you gave it to them. So, people rise to power because you say: oh my goodness, I’m supposed to listen to Donald Trump…the more the world stops paying attention, the more the universe goes – Baby! Love. There’s something bigger. The moment you believe that there’s a greater power, a greater purpose for all of this, the less he will be in office. That’s what this is about. We don’t focus on Donald Trump, we focus on YOUR awakening. When you become pure light and currency and you affect the next person and the next person, he comes out of power. It’s about YOUR awakening. It’s all the Atlanteans who are rising and awakening. Imagine this is all a currency war. I’m talking about currency of the heart. And currency in here and currency out here are the same thing. The more you can have currency in here, the richer and happier you become. It’s all currency – of love, compassion, empathy. But if you look at what’s happening out here, it’s a currency war. What happened with all those people on that huge walk – they were not afraid. Their brains lit up differently. They were not coming together in anger or hatred; they came in love; love that echoed through every currency of the universe. And it is THIS that creates transformation. All those women having their demonstration, that was the largest percent of Atlanteans gathered at one time. Not everyone, but the majority who traveled were all Atlantean women. They are healers. They heal pain. They don’t buy into pain. They HEAL pain. Atlantean women don’t buy into anger; they transcend it. Atlantean women don’t buy into fear; they heal. They don’t buy into what’s in front of them. They see the desperation. We don’t buy into desperation, we rise above it. This is a currency war, but also a war between reptiles. All the reptiles are going after each other, where before they all went after YOU. Now they’re going after each other. For where we are: AMEN! HALLELJUAH! Knock each other out and let all these Atlantean men and women LET THEM RISE and create the change so these types of reptiles will NEVER be in power again. HUGE!!! HUGE!!! HUGE!!!! This has NEVER been possible in 2K years. All of this is currency, currency of love and energy; the currency of FREEDOM! This blog is an excerpt from the Pathway to Consciousness event in January 2017. The next Pathway to Consciousness event will be in Toronto in the Fall 2017. Bart Smit's next public event scheduled will be at the Akasha's Den June 3, 2017. Bart will be channeling Dr. Williams. ]]>[email protected] (Bart Smit)BlogTue, 18 Apr 2017 11:37:00 +0000I am not here to be the pain of myself or the pain of the world.https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/65-i-am-not-here-to-be-the-pain-of-myself-or-the-pain-of-the-world https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/65-i-am-not-here-to-be-the-pain-of-myself-or-the-pain-of-the-world As we’re moving into a new world’s economy, and the United States is going through it’s own battles, this is not a time to process through your lower chakras or other people’s needs or emotions or to let these lower chakras be stimulated. This is the time for you to hold your heart, the part of this quadrant and the reptilian brain and frontal lobe in such silence and stillness because this is how the world gets lifted to great Consciousness. To help us achieve this, Dr. Williams has given us a prayer: I’m here to experience liberation. I am not here to process everyone else’s needs or emotions. I’m not a slave to my emotions or anyone else’s. I’m here for liberation. I’m here to be awakened. I am not here for my lower chakras
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18804, 4207, 322, 15, 575, 36, 3508, 13, 3921, 292, 355, 27720, 789, 275, 4780, 15, 187, 187, 51, 15, 209, 575, 43, 15, 209, 575, 49256, 15860, 285, 500, 15, 209, 575, 49, 15, 209, 575, 55, 552, 13, 475, 9083, 15, 3555, 15, 399, 11, 4299, 1967, 7444, 313, 9430, 10, 470, 1047, 8972, 905, 20197, 14341, 14, 545, 16, 2941, 883, 17864, 4622, 4207, 187, 187, 55, 15, 575, 34, 15, 575, 44, 36687, 729, 13, 500, 8634, 39, 15, 575, 18102, 7173, 285, 329, 15, 575, 55, 15, 575, 8944, 343, 30568, 13, 475, 9083, 15, 3555, 15, 399, 11, 4299, 2357, 7444, 313, 8012, 10, 16331, 1235, 1619, 905, 20197, 14341, 14, 394, 16, 2904, 520, 15, 15645, 24, 4622, 696, 187, 187, 52, 15, 575, 43, 15, 575, 19968, 1397, 4742, 13, 500 ]	does not enter a second-order perturbative analysis. Figure from Ref.[@Vary:2009gt].[]{data-label="n_odd"}](n_odd.eps){width="8cm"} To date, we have found no matrix element trends with increasing transverse energy that would imply new divergences. All such matrix elements sets we examined, within a perturbative analysis, fall faster than $1/\sqrt{n'}$. Also, we found no sets that remained constant with increasing $m'$ (and thus $m$) holding $n,n'$ fixed. As a result of this initial analysis, we anticipate that straightforward adoption of counterterm methods previously introduced [@JPV214] will be sufficient for managing the identified divergences in BLFQ. As another example of the interacting cavity mode QED, we present in Fig.\[eigenvalues\_4x4.eps\] the eigenvalue spectra for a Hamiltonian matrix that includes lepton and lepton-photon Fock spaces. The leptons are now massive with $\bar m_l=0.511$ MeV, and the HO parameters are $\Omega=0.1$ MeV and $M_0=\bar m_l$. The other basis parameters are chosen as $K=3$, $N_{max}=2$ and $M_j=1/2$. The eigenvalues are shown as a function of the strength of the coupling with respect to the coupling at QED, with $g_{\rm QED}=\sqrt{4\pi\alpha}$. Since the instantaneous fermion interaction term only contributes when all the leptons and photons of the process have their spins aligned, this particular case only involves the photon emission vertex interaction (see e.g. Ref.[@Anommm]). Application of the sector-dependent renormalization [@Karmanov] will shift these eigenvalues such that the lowest one will obtain the value $E_0=\frac{\bar m^2+M_0\Omega}{K}$, where $\bar m$ is the mass of the lowest state fermion. As we increase the cutoffs $K,N_{max}$, the evaluation of the electron anomalous magnetic moment will serve as an important precision test for our method [@Anommm]. ![ Eigenvalues of a cavity mode QED Hamiltonian, which includes lepton and lepton-photon Fock spaces, as a function of the strength of the coupling ($g_{\rm QED}=\sqrt{4\pi\alpha}$). The HO parameters are $\Omega=0.1$ MeV and $M_0=0.511$ MeV, and the other basis parameters are $K=3$, $N_{max}=2$ and $M_j=1/2$.[]{data-label="eigenvalues_4x4.eps"}](eigenvalues_4x4.eps){width="9cm"} Conclusions =========== Following successful methods of [ab initio]{} nuclear many-body theory, we have introduced a basis light-front quantization (BLFQ) approach to Hamiltonian quantum field theory. With a cavity mode treatment of massless non-interacting QED we showed how the number of many-parton basis states exhibit a dramatic rise as the cutoffs are elevated. In order to extend our method to QCD, we presented two methods for treating the color degree of freedom and demonstrated sample measures of the efficiency gains for global color singlets over basis states with color-singlet projection alone. For the interacting cavity mode QED we outlined our approach to managing the expected divergences in a manner that will preserve all the symmetries of the theory. An initial inspection of the interaction vertices of QED in the BLFQ approach shows smooth behaviors that, following a second-order perturbative analysis, are not expected to lead to divergences. It appears that the cavity mode treatment, with the type of basis spaces we have selected, will encounter the divergences in a more subtle fashion as cutoffs are elevated. The evaluation of the electron anomalous magnetic moment will be an important test to our method as we expand our basis space. [99]{} H. C. Pauli and S. J. Brodsky, Phys. Rev. D [32]{}, (1985)1993; S. J. Brodsky, H. C. 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Let m = 0.1 - 0.9. Let w = m - -0.9. What is the nearest to w in 0.2, 5, x? 0.2 Let y = -65 + 62. Which is the closest to -6? (a) 4 (b) 5 (c) y c Let i be ((-4)/3)/(8 - (-396)/(-45)). Let f = 0.1 - 2.1. Which is the closest to f? (a) -0.3 (b) i (c) -3 c Suppose -4y - 110 = 2g, -5y - 145 = -g + 5g. Let q = 15 + y. Let v be q/6 + 2/1. Which is the closest to -0.1? (a) 1/4 (b) 3 (c) v a Let m(k) = k*3 + 7k*2 + 10k + 3. Let g be m(-5). Let z = -6 - 40. Let s be (-2)/(z/25) - 1. Which is the nearest to g? (a) s (b) 0.4 (c) -3 b Let z be 4 + (2 - 35/6). Which is the nearest to -2/7? (a) z (b) -1/3 (c) -3/8 b Let v be ((-2)/6)/((-2)/4). Let z = -3.6 + 3. Let i = z - -5.6. What is the nearest to 1 in i, 4, v? v Let h = 3 + -3.1. Let q = -2.6 - -3. Let k = q - 0.9. Which is the nearest to 2/7? (a) -3/7 (b) h (c) k b Let q = 2 - 3. Let k be (35/(-70))/(14/(-8)). What is the closest to 0.1 in q, k, -0.1? k Let r = -40 - -40. Suppose -j + 8 - 3 = 0. What is the closest to -1 in -3, r, j? r Suppose -4c + 3 = -1. Let o = 115 - 107.9. Let h = o + -7. What is the closest to c in 0.5, 0.3, h? 0.5 Let i = 351524 + -3875834/11. Let k = 820 + i. Let t = k - -389/88. Which is the nearest to -1/3? (a) t (b) -0.2 (c) -5 b Let v = -57/2 + 29. Which is the nearest to 0.1? (a) -5/3 (b) -3 (c) v c Let l be 9/(-3) + (30/9 - 0). What is the nearest to -0.9 in l, -0.1, 0.2? -0.1 Let r = 6 - 11. Which is the closest to 2? (a) r (b) 0.4 (c) -2/9 b Let g = 2.2 + -2. Let y be 7/(-12) + (-2)/(-8). Let c = -92 - -88. What is the nearest to y in c, -0.4, g? -0.4 Let i = 24 - 25.7. Let f = i + 2. Let w = 0.5 + -1. Which is the closest to 0? (a) f (b) w (c) -0.4 a Let p = 0.1 + 0.4. Let l = p + -0.3. Let r = l - 0.1. Which is the nearest to r? (a) 0.1 (b) 2 (c) -3 a Let n = 4 + -4.6. Let u = -0.4 - n. Which is the closest to -3? (a) u (b) 3 (c) 4 a Let j = 0.2 - 0.7. Let m = j - -3.5. Let l = -13/115 - 2/23. Which is the nearest to 0.1? (a) m (b) 0.5 (c) l c Let r(z) = z - 12. Let h be r(12). Suppose 11 = -4x - x + 2g, 15 = -3x - 3g. Which is the nearest to h? (a) x (b) 0.2 (c) -0.4 b Let p = 1.7 + -2.6. Let q = p + -0.1. Let h = -1/76 - -155/228. What is the closest to h in -3, q, 0.3? 0.3 Let f = -6 + 6.6. Let p = f - 0.6. Let l = -1006/33 - -92/3. What is the nearest to p in 0.1, -3/7, l? 0.1 Suppose -2m + 7m = -10. What is the nearest to 0.1 in -0.5, -1/11, m? -1/11 Let h = 22.1 + -22. Let p be 1 + -3 + 0 - -7. What is the nearest to h in -4, p, 0.4? 0.4 Let u = -1.1 - -0.1. Let j = 5.84 + 0.16. Let z = j + -5.5. Which is the closest to u? (a) z (b) -1/3 (c) 1 b Let m be 15/505/(-2). Let i be (1/5)/((-4)/(Background The six-carbon circular non-proteinogenic compound l-pipecolic acid is an important chiral drug intermediate with many applications in the pharmaceutical industry. In the present study, we developed a metabolically engineered strain of Escherichia coli for the overproduction of l-pipecolic acid from glucose. Results The metabolic pathway from l-lysine to l-pipecolic acid was constructed initially by introducing lysine cyclodeaminase (LCD). Next, l-lysine metabolic flux from glucose was amplified by the plasmid-based overexpression of dapA, lysC, and lysA under the control of the strong trc promoter to increase the biosynthetic pool of the precursor l-lysine. Additionally, since the catalytic efficiency of the key enzyme LCD is limited by the cofactor NAD+, the intracellular pyridine nucleotide concentration was rebalanced by expressing the pntAB gene encoding the transhydrogenase, which elevated the proportion of LCD with bound NAD+ and enhanced l-pipecolic acid production significantly. Further, optimization of Fe2+ and surfactant in the fermentation process resulted in 5.33 g/L l-pipecolic acid, with a yield of 0.13 g/g of glucose via fed-batch cultivation. Conclusions We expanded the metabolic pathway for the synthesis of the chiral pharmaceutical intermediate l-pipecolic acid in E. coli. Using the engineered E. coli, a fast and efficient fermentative production of l-pipecolic acid was achieved. This strategy could be applied to the biosynthesis of other commercially and industrially important chiral compounds containing piperidine rings. Chirality plays a key role not only in the life of plants and animals but also in the pharmaceutical, agricultural and chemical industries [1, 2]. Particularly, in the pharmaceutical industry, 56% of all drugs currently in use are chiral and screening and production of single enantiomers of chiral intermediates is increasingly important [3]. l-pipecolic acid (l-PA) is a non-proteinogenic compound and key chiral intermediate in the synthesis of many important groups of drugs [4] (Fig. 1). l-PA with a high optical purity is a precursor for the anaesthetics ropivacaine, bupivacaine and chloroprocaine which are widely used in local anaesthesia [5]; and it is also a precursor for the macrolide-pipecolate immunosuppressor rapamycin, FK-506 and FK-520 that are indispensable in the clinic [6]. Similar to the preparation of most of the other enantiomeric organic compounds, pure l-pipecolic acid enantiomers are mainly produced by chemical enantioselective synthesis [7] and stereoselective transformation [8]. However, the chemical methods for commercial-scale preparation of l-PA are complex and environmentally unfriendly [9]. Total biosynthesis of chiral drug intermediates is a more environmentally friendly approach for the preparation of affordable pharmaceuticals [10]. Bioproduction of l-PA has been extensively investigated, mainly due to its close relationship with l-lysine metabolism [11, 12]. Previous studies [11–13] have established two basic routes for converting l-lysine to l-PA. The first involves the loss of the α
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θ and ${A_{x}}^{\prime} = \sqrt{A_{x}^{2} + A_{y}^{2}}$ are accrued. Phase II, as shown in [Figure 3(b)](#fig3){ref-type="fig"}, is to rotate the $\overset{⃑}{g^{\prime}}$ vector on the x-z plane and have it aligned to the x-axis, as looking from the pointing direction of the y-axis (right side). The rotation is performed by 2D CORDIC on the x-z plane with the initial 2D vector (A~x~′, A~z~) and have it aligned to the x-axis. The iterative equations are shown in [Figure 3(b)](#fig3){ref-type="fig"}, and the rotated angle δ is accrued through CORDIC operations and φ = π/2 − δ. As you can see, the tilt angle, φ, is obtained with simple shifting and addition operations only by this proposed algorithm. 2.4. System Design and Realization {#sec2.4} ---------------------------------- ### 2.4.1. Definition of Head Position Angles {#sec2.4.1} In the proposed sensing system, an accelerometer is attached to the forehead of the subject mounted with 3M™ Micropore™ Surgical Tape in the orientation shown in [Figure 4(a)](#fig4){ref-type="fig"}, where x-axis points toward the head of the head, y-axis points to the right-hand side of the body, and z-axis points to the front of the head. With the accelerometer attached to the forehead to comply with the defined orientation, the head would rotate along the x-axis. Therefore, the rotation angle θ and the inclination angle φ can be calculated as in ([3](#EEq2){ref-type="disp-formula"}) for a different orientation compared with those in ([2](#EEq1){ref-type="disp-formula"}). It is also represented in [Figure 4(b)](#fig4){ref-type="fig"}. $$\begin{matrix} {\varphi = \arctan\left( \frac{A_{x}}{\sqrt{{A_{y}}^{2} + {A_{z}}^{2}}} \right),} \\ {\theta = \arctan\left( \frac{A_{y}}{A_{z}} \right) + \sigma \cdot \lambda \cdot \pi,} \\ \end{matrix}$$where σ = 0, if A~z~ ≥ 0; otherwise, σ = 1. λ = 1, if A~y~ ≥ 0; otherwise, λ = −1. ### 2.4.2. System Realization {#sec2.4.2} The overall system consists of front-end sensing subsystem and back-end data conversion subsystem. The front-end subsystem is the accelerometer sensor with a microcontroller for data acquisition and tilting angle transformation in digital formats. The angle information is then passed to the back-end subsystem for signal conversion into analog voltage signals to be hooked up with the PSG devices. Digital information has to be converted into analog signals because the tilting information has to be integrated with the PSG devices through their AUX inputs which are available for most of the PSG devices. Depending on how the data can be passed from front-end to back-end, the system can be realized as a wired system or a wireless system. ### 2.4.3. Wired Sensing System Implementation {#sec2.4.3} The wired system block diagram is shown in [Figure 5](#fig5){ref-type="fig"} and mainly consisted of a microcontroller unit (MCU; ADuC7020; Analog Devices Inc.) and accelerometer modules (ADXL345, Analog Devices Inc.). The system was integrated into the PSG (Alice 5; Philips Respironics Inc.) for in-line and real-time application. The firmware executed on the MCU was developed in C language under the software of uVision4 IDE. The MCU core clock was set at 10.44 MHz. The accelerometer module was an ultralow-power high-performance 3-axis digital accelerometer. It has the sensitivity of 3.9 mg/LSB with a ±2g range and an on-chip low-pass filter for the removal of high-frequency noise. The communication between the accelerometers and MCU was through an I2C bus on a wired cable. The sampling rate of the accelerometer was set to be 100 Hz, and therefore, the MCU received the rectangular coordination (A~x~, A~y~, and A~z~) of vector (−1g) from a 3-axis digital accelerometer for every 10 ms. The data were then transformed to the angular domain for tilting angle identifications. Four channels of on-chip digital-to-analog converters (DACs) were included in the MCU and converted the in-line calculated angles into analog voltages representing the inclination information. Then, the information was directly transferred to the auxiliary inputs of the PSG for the study of remission of the patient with OSAS. This is the system that has been implemented for the IRB tests. ### 2.4.4. Wireless Sensing System Implementation {#sec2.4.4} If the tilting information of the head is transmitted wirelessly to the back-end data conversion subsystem and hooked up to the PSG, then it is the wireless sensing system. With this implementation, a front-end sensing subsystem could be attached on the forehead of the subject and without any cable connected to the PSG. In this front-end sensing subsystem, a module named "BASIC" was developed. BASIC stands for BLE-enabled Accelerometer-based Sensing In a Chip-packaging and is a fusion of A, B, and C technologies which are the accelerometer-based inertial sensing, Bluetooth low-energy (BLE) technology, and CORDIC-based tilting angle transformation algorithm. It is an integration of the accelerometer with the BLE module with CORDIC-based tilting angle transformation algorithm realized in the SoC of the BLE module. So, the module is capable of transmitting the tilting information according to the configured orientation over the air wirelessly by itself. The photo of the BASIC module and its block diagram is shown in [Figure 6](#fig6){ref-type="fig"}. With this module attached to the forehead of the subject, there will be no wired connection from the sensing front-end to the data conversion back-end which is then attached to the PSG device. The back-end system can be simply modified from [Figure 5](#fig5){ref-type="fig"} using a BLE module to receive the transmitted data from the wireless sensing front-end subsystem, for example, the BASIC module; then, the received data are filled into the DACs inside the MCU for signal conversion and hooked up to the PSG device. 3. Results {#sec3} ========== In this section, the accuracy of the CORDIC-based tilting sensing algorithm-converted information is analyzed by comparing the angle calculated using mathematical equations as in ([3](#EEq2){ref-type="disp-formula"}). Then, the accuracy of the proposed sensing system was tested with a three-axis rotation platform to measure its actual accuracy under a precise controlled environment. Finally, the results of the system applied in a clinical IRB test is shown to prove the usability of the system for an unmet medical need. 3.1. Precision of the CORDIC-Based Tilting Sensing Algorithm {#sec3.1} ------------------------------------------------------------ Validation of the algorithm accuracy was performed to show its precision. The number of iterations executed in the CORDIC-based algorithm can greatly impact the accuracy. Generally, the more iterations executed, the better accuracy can be obtained. But, the trade-off is to increase the computation time. An optimization was performed to find the number of iteration with acceptable accuracy and computation time. Hereby, different numbers of iterations from 4 to 12 were tested and compared with those of the calculated angles from the offline mathematical calculations. The results are summarized in [Figure 7](#fig7){ref-type="fig"}. It indicated that to meet the medical requirement of accuracy at 1°\~2°, an acceptable accuracy of ±0.8 degrees for rotation angles and ±0.49 degrees for inclination angle was calculated by 8 iterations with the computation time of 795.9 ms. Such computation time was still much faster than the one from the original trigonometric calculation. 3.2. Accuracy of the Sensing System with an Accelerometer {#sec3.2} --------------------------------------------------------- The accuracy of the sensing system with the actual accelerometer was confirmed through testing on a controllable three-axis rotation platform (with a tri-axis step motor controller, TL-3T, from Tanlian E-O Co. Ltd.), as shown in [Figure 8(a)](#fig8){ref-type="fig"}. The accelerometer sensing module being tested was placed at the center of the platform. During such testing, the tilting angles of the platform are controlled using precise step motors on the x-axis, y-axis, and z-axis with a resolution of 0.0025 degrees per step. In addition, the tilting angle of the
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17442, 273, 253, 330, 6435, 10280, 15, 1723, 13, 271, 7466, 273, 436, 10280, 13, 3738, 3309, 13, 1057, 417, 1646, 281, 320, 4209, 281, 2847, 2048, 273, 6005, 9, 57, 2769, 82, 1630, 15, 20, 481, 5131, 2616, 403, 4518, 3058, 13, 299, 15, 72, 904, 21871, 26790, 366 ]	with a dermatitis condition that clears up if he avoids certain agents, receives a zero percent impairment even if that person cannot return to the type of employment that he was performing at the time of his exposure and outbreak (this is the example that applies to the claimant herein). However, under "Class two, 10% to 20%, Example one", Page 145, a housewife that develops a chronic dermatitis that requires some intermittent treatment receives a ten percent impairment. Thus, it is obvious that the effect that the skin condition has upon one's economic loss, which is the heart of the wage loss concept, is not a factor in making a determination of impairment to the skin under the Guides. Collaterally, but not a factor in the undersigned's findings, is the pronouncement in Trindade, supra, that since the indispensable requisite of the wage loss concept is economic 950 loss, a classification which distinguishes between eligible and ineligible claimants on a basis which bears no reasonable relationship to their respective economic loss is violative of certain Federal and State Constitutional guarantees. The claimant's physician has opined that the claimant would have a permanent impairment as a result of his condition if he continued to work with wet cement. However, the claimant would encounter increasing physical problems from the dermatitis that would eventually totally incapacitate him from working in that employment. Additionally, the employer/carrier could assert the affirmative defense of a voluntarily inflicted injury against claims for indemnity benefits under those circumstances. Accord: Ernest Waters Construction Company v. Mills, 51 So.2d 180 (Fla. 1951). On the other hand, if one accepts the premise that the Guides are exclusive in this particular situation, and the claimant accepts other less remunerative employment, he would not be entitled to wage loss benefits because the Guides do not provide an impairment rating. I find, however, that under the facts of this particular case, the Guides do not deal with the effect that the dermatitis has upon the claimant's ability to return to and perform the various physical activities of the employment in which he developed the occupational disease as opposed to the claimant's ability to carry out daily living activities as defined by the Guides. The claimant's treating physician, Harold Seder, M.D., a Board Certified Dermatologist, has opined that the claimant would have a permanent impairment if the claimant continued to work with wet cement and that he would eventually become totally disabled from working in that employment as a result of the dermatitis. Dr. Seder also observed the outbreak of the dermatitis upon the claimant's skin. It was Dr. Seder's opinion that the claimant should not return to employment involving contact with wet cement. The undersigned accepts the testimony of Dr. Seder and finds that this expert opinion is competent and substantial evidence that establishes the existence of a permanent impairment of an unknown degree under the facts of this particular case and that this evidence meets generally acceptable medical standards for determining impairment, especially in light of the fact that the doctor was not aware of any guides other than the A.M.A. Guides for determining dermatological impairment. Claimant clearly suffers from permanent impairment which has resulted in his "incapacity because of the injury to earn in the same or any other employment the wages which the employee was receiving at the time of the injury." (emphasis added). Section 440.02(9), Florida Statutes. Due to his skin condition, claimant cannot work in his chosen occupation, where he earned a relatively high salary, and, in all likelihood, is unable to earn an equal wage in other employment without further training. Although not presented as an issue, we note that neither the employer nor its servicing agent has provided claimant any rehabilitation services as required by Section 440.49(1)(a), Florida Statutes.[1] In the 951 situation before us, claimant's condition is directly related to his occupation. Under the terms of the Guides, there is no impairment if the injury does not affect the employee's daily living. In the case sub judice, claimant's skin condition does not affect his daily living as long as he does not work in his job. Essentially, as long as claimant does nothing, there is no impairment. In Trindade v. Abbey Road Beef 'n Booze, 443 So.2d 1007, 1011 (Fla. 1st DCA 1983), this court held: We have the obligation of interpreting a statute in a manner consistent with the legislative intent, to the extent it is ascertainable and can lawfully be implemented. We have the further obligation of applying an interpretation upholding the constitutionality of a statute, if such an interpretation is permissible. Department of Insurance, State of Florida v. Southeast Volusia Hospital District, 438 So.2d 815 (Fla. 1983). Accordingly, although the Guides do not award the permanent impairment to claimant's skin condition, we affirm and agree with the deputy that, under the particular factual circumstances at bar, the Guides are not exclusively controlling because the Guides do not address claimant's evident economic loss, which is the basis of the wage-loss concept. Trindade at 1012. As to the award of temporary partial disability benefits, the deputy's finding that claimant conducted a valid, good-faith job search after his release by his doctor to return to some other type of employment is supported by competent, substantial evidence. We therefore affirm that award. We certify to the Supreme Court of Florida the following question as one of great public importance: DO THE AMA GUIDES TO THE EVALUATION OF PERMANENT IMPAIRMENT APPLY AND PRECLUDE A PERMANENT IMPAIRMENT RATING WHERE CLAIMANT SUFFERS A DISABILITY DUE TO OCCUPATIONAL DISEASE WHICH PERMANENTLY IMPAIRS CLAIMANT'S ABILITY TO WORK, RESULTING IN ECONOMIC LOSS, BUT DOES NOT AFFECT "THE ACTIVITIES OF DAILY LIVING?" WIGGINTON and BARFIELD, JJ., Concur. NOTES [1] Section 440.49(1)(a), Florida Statutes, provides, in pertinent part, as follows: (1) REHABILITATION OF INJURED EMPLOYEES. (a) When an employee has suffered an injury covered by this chapter and it appears that the injury will preclude the employee from earning wages equal to wages earned prior to the injury, the employee shall be entitled to prompt rehabilitation services. The employer or carrier, at its own expense, shall provide such injured employee with appropriate training and education for suitable gainful employment and may cooperate with federal and state agencies for vocational education and with any public or private agency cooperating with such federal and state agencies in the vocational rehabilitation of such injured employees. For purposes of this section only, "suitable gainful employment" means employment or self-employment which is reasonably attainable in light of the individual's age, education, previous occupation, and injury and which offers an opportunity to restore the individual as soon as practicable and as nearly as possible to his average weekly earnings at the time of injury... . You can try these similar gifts instead. Vintage Personalized Beer Pong Specialist Bar and Pub Sign He knows just how he wants to spend a lazy Saturday. Invite his friends over and organize a beer pong tournament. Who will be champion? There's no doubt about it, he's the best. It's sign for a guy who has the skills. This product is no longer listed on FindGift.com by this retailer. Check the Similar Gifts section above to find other gifts that may be suitable.Q: Is it safe to set Lua Table data from multiple C++ threads? As the title states. I'm curious if it's safe to set data in different Lua tables that exist in the same lua state. From multiple C++ threads. I'm asking this because my current system actually has a separating between Lua's data, and C++'s data, with Lua driving the majority of the game's update and loop - and C++ handling lower level details such as math, rendering, resources, and physics. After the physics update, I have to waste time in having an entire phase for Lua to update it's own internals for Serialization and grabbing references. A: No, Lua's state is not really thread-safe by default, so you can't access the same state from many threads without work on your part. Lua will call lua_lock and lua_unlock at appropriate points, but by default these methods do nothing and you must #define them to implementations that actually take the appropriate platform-specific critical section. However, that implements the most bare-bones approach to thread synchronization which just makes sure only one thread is running Lua at a time. You can see here for more information. A better approach might be trying to reorganize your update loop so something else can happen concurrently with the Lua state sync, which only itself happens on one thread. Perhaps after physics is done processing, you can both synchronize Lua and prepare your graphics calls at the same time? Or something similar; it's admittedly hard to say without knowing more about your architecture. Butyrate and acetyl-carnitine inhibit the cytogenetic expression of the fragile X in vitro. Cytogenetic expression of the fragile site at Xq27.3 is only found in those patients who have a full mutation of the FMR1 gene, i.e., a large amplification of the CGG repeat. However, an expansion of this repeat, although necessary, does not seem to be sufficient to cause expression of fra(X)(q27.3). Other factors are clearly needed, e.g., thymidylate
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667, 10021, 1055, 15, 187, 187, 20431, 44052, 367, 4863, 1108, 380, 5779, 980, 323, 29077, 6089, 1255, 187, 187, 36, 706, 376, 367, 583, 1108, 187, 187, 2347, 281, 513, 27, 380, 27911, 376, 24543, 830, 1103 ]	We assessed patients using the respiratory disturbance index (RDI), the Epworth sleepiness scale (ESS), body mass index (BMI), fasting serum total cholesterol, triglycerides (TGs), and C-reactive protein (CRP). Mean RDI scores were 0.53, 10.6, 27.3, and 45.1 in the control group (n = 21), mild (n = 29), moderate (n = 31), and severe (n = 27), respectively. Partial correlation analysis showed that patients' RDI score was significantly correlated with CRP after adjustment for BMI. Partial correlation analysis showed that the mean ESS score correlated significantly with the CRP level after adjustment for BMI. Partial correlation analysis showed that the mean least oxygen saturation was significantly correlated with CRP after adjustment for BMI Pearson's correlation coefficients examining the relationship between BMI and total cholesterol; TG and CRP were found to be 0.531, 0.401, and 0.321. The correlation of CRP levels with disease severity as assessed by RDI, ESS, and least oxygen saturation was significant after adjustment for BMI. Patients with OSA have elevated serum levels of high-sensitivity-CRP, a marker for inflammation and an independent risk predictor for cardiovascular morbidity.Q: Detect if an iPhone app with given Apple ID and Bundle ID is already installed Is it possible to detect if an app with the given Bundle ID and Apple ID is already installed on the device? The app does not implement a custom URL Scheme. A: For the sake of completeness - the answer is no. // English (Ireland) [en-ie] import dayjs from 'dayjs' const locale = { name: 'en-ie', weekdays: 'Sunday_Monday_Tuesday_Wednesday_Thursday_Friday_Saturday'.split('_'), months: 'January_February_March_April_May_June_July_August_September_October_November_December'.split('_'), weekStart: 1, weekdaysShort: 'Sun_Mon_Tue_Wed_Thu_Fri_Sat'.split('_'), monthsShort: 'Jan_Feb_Mar_Apr_May_Jun_Jul_Aug_Sep_Oct_Nov_Dec'.split('_'), weekdaysMin: 'Su_Mo_Tu_We_Th_Fr_Sa'.split('_'), ordinal: n => n, formats: { LT: 'HH:mm', LTS: 'HH:mm:ss', L: 'DD/MM/YYYY', LL: 'D MMMM YYYY', LLL: 'D MMMM YYYY HH:mm', LLLL: 'dddd D MMMM YYYY HH:mm' }, relativeTime: { future: 'in %s', past: '%s ago', s: 'a few seconds', m: 'a minute', mm: '%d minutes', h: 'an hour', hh: '%d hours', d: 'a day', dd: '%d days', M: 'a month', MM: '%d months', y: 'a year', yy: '%d years' } } dayjs.locale(locale, null, true) export default locale Closer to God, closer to nature! Archive for 11:52 AM During the students´ holiday, a youth convention was organized at the Camp of our church, situated in Porumbacu. The number of participants was not very large, however those who attended enjoyed a time of beautiful fellowship, as well as the joy of winter time. The topics presented on this opportunity centered around „Friendship“, a relationship analyzed from the perspective of interpersonal interaction, the way in which we interact with the group of which we are a part, namely family and church; also, the friendship with Jesus, which will visibly bring about an improvement of the other social relationships.Q: ESR of Ceramic Capacitor I have been doing a bit research on ceramic capacitors, as I need one for the output of my synchronous buck converter. And as its very common that ESR is not straight forwardly given in the data sheets, we have to calculate it ourselves by Dissipation Factor value given at a certain frequency (normally 120 Hz) for a certain capacitance value. $$ESR = \dfrac{D \cdot F}{2 \pi f C}$$ For e.g if i have this ceramic capacitor I can calculate the ESR as $$ \dfrac{0.05}{2 \pi \cdot 120 \cdot 470 \mu F} = 141m\Omega$$ (page 1 of data sheet, calculating for 470uF cap). Now my question is, what if I am using this capacitor in my circuit at 100kHz? Its ESR should decrease right? As I think ESR should decrease with increasing the frequency. But the Dissipation factor increases with the increase in frequency as well. So how can one estimate the capacitor ESR at a high frequency? As there is no Frequency vs ESR OR Frequency vs D.F graphical relation given in the data sheets (I have gone through almost 100s of data sheets). So is there any way by which I can estimate the ESR of this capacitor at a higher frequency of 100kHz? Actually I will be charging my battery cell with the help of my buck converter and I need the capacitor ESR to be less than 10mOhms, because that is my Battery cell's ESR (mentioned in the data sheet), so I am trying to look for a ceramic capacitor with a lower ESR than this, for minimizing my voltage ripple at the output. Your helpful comments would be appreciated. Thankyou! A: While ESR is not always given it is often easy to find on a better manufacturers website. Many have online or downloadable tools that will show you all of the information you could ever want about a cap. With the rise of the need to simulate PDN for everyday boards, people have been demanding exactly this kind of information. For example take a look at Murata's simsurfing tool It's free of course and all you do is select a capacitor from the list and among other things you can see the graph of ESR and impedance vs frequency. If you're simulating it's easy to extract a simple RLC model from the data. A: If you are using that capacitor at 100kHz I might be interested in it's ESL - series inductance - it's a leaded part and quite large and this may swamp the resistance and give you horrible resonance problems: - I'd be looking for a capacitor that was specified more fully and it would more likely be a radial electrolytic. I would also consider the benefits of having it in parallel with a 1uF ceramic capacitor and maybe a 100nF - these sorts of devices are usually quite well specified by for high frequencies. My advice is find a more appropriate solution. Now my question is, what if I am using this capacitor in my circuit at 100kHz? Its ESR should decrease right? No, dissipation factor applies at a specific frequency - you can't just calculate ESR at F1 and expect it to become a different value at F2. Wiki tells us: - DF will vary depending on the dielectric material and the frequency of the electrical signals. A: The ESR equation works so long as you are below the resonant frequency of the cap. If you take a look at the impedance "notch" curve, the ESR should decrease up to the point where the cap is at its resonant point, after which you'll see the parasitic ESL begin to become more pronounced. This is where the equation above is incomplete (at the resonant frequency and above). Power Yoga Poses -The Cheapest Favour to your Body December 7, 2015 The approach of Power Yoga is the latest buzz that is bowling over the gaggles, but a ton of people are just muddled between the two terms i.e. ‘Yoga’ and ‘Power Yoga’ are they same? No, they are not alike; Yoga is the traditional system that is followed by the meditation process and steps to glom onto the crown of mind control and self recognition. While on the other hand the meditation steps followed in the Power Yoga aims at shaping the mind to be peaceful and calm. Its direction is towards the increased level of cholesterol in the body, Power Yoga targets to care about the cholesterol level. So this was all about ‘What is Power Yoga’. Power Yoga has grown throughout the world as this yoga does not involves just the strengthening of body and movements but it enmeshes the whole body and stepped out with flexibility and toning of body muscles not only this, a Power Yoga also educes the characteristics of what a good workouts can do. Power Yoga for weight Loss is one of the most crowd-pleasing forms of yoga that is considered to be most impressive and productive than other alternative forms. Power Yoga for weight Loss is well chosen as the simple yet natural way for losing weight. Practicing Power yoga on a regular basis has surely abetted countless people in paring down and gaining up weight. Weight Loss through Power Yoga is the best option that is now preferred by the herd as it does not have any adverse effect. Power Yoga Poses – The Postures for Mental Wellness Cobra Pose – How to do: The Cobra poses formants
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6179, 9954, 15, 25081, 731, 253, 10402, 3767, 273, 253, 4410, 4437, 3261, 562, 387, 253, 8762, 14, 69, 15172, 31504, 13, 8958, 436, 369, 616, 2457, 1007, 387, 3968, 15, 1583, 497, 7107, 13, 1907, 644, 391, 24695, 432, 3722, 275, 8387, 1041 ]	reeducation, cosmetic surgery if necessary, and they'll never have to work another day as long as they live—but they will want to work. Almost all of them do. I expect the navy will find places for them, paid consultants for their submarine warfare department, that sort of thing." "I want to meet them," the president said impulsively. "That can be arranged, sir, but it will have to be discreet," Moore cautioned. "Camp David, that ought to be secure enough. And Ryan, Judge, I want him taken care of." "Understood, sir. We're bringing him along rather quickly already. He has a big future with us." Tyuratam, USSR The reason Red October had been ordered to dive long before dawn was orbiting the earth at a height of eight hundred kilometers. The size of a Greyhound bus, Albatross 8 had been sent aloft eleven months earlier by a heavy-lift booster from the Cosmodrome at Tyuratam. The massive satellite, called a RORSAT, for radar ocean reconnaissance satellite, was specifically designed for maritime surveillance. Albatross 8 passed over Pamlico Sound at 1131 local time. Its on-board programming was designed to trace thermal receptors over the entire visible horizon, interrogating everything in sight and locking on any signature that fit its acquisition parameters. As it continued on its orbit and passed over elements of the U.S. fleet, the New Jersey's jammers were aimed upward to scramble its signal. The satellite's tape systems dutifully recorded this. The jamming would tell the operators something about American electronic warfare systems. As Albatross 8 crossed the pole, the parabolic dish on its front tracked in on the carrier signal of another bird, the Iskra communications satellite. When the reconnaissance satellite located its higher flying cousin, a laser side-link transmitted the contents of the Albatross' tape bank. The Iskra immediately relayed this to the ground station at Tyuratam. The signal was also received by a fifteen-meter dish located in western China which was operated by the U.S. National Security Agency in cooperation with the Chinese, who used the data received for their own purposes. The Americans transmitted it via their own communications satellite to NSA headquarters at Fort Meade, Maryland. At almost the same time the digital signal was examined by two teams of experts five thousand miles apart. "Clear weather," a technician moaned. "Now we get clear weather!" "Enjoy it while you can, Comrade." His neighbor at the next console was watching data from a geosynchronous weather satellite that monitored the Western Hemisphere. Knowing the weather over a hostile country can have great strategic value. "There's another cold front approaching their coast. Their winter has been like ours. I hope they are enjoying it." "Our men at sea will not." The technician mentally shuddered at the thought of being at sea in a major storm. He'd taken a Black Sea cruise the previous summer and become hopelessly seasick. "Aha! What is this? Colonel!" "Yes, Comrade?" The colonel supervising the watch came over quickly. "See here, Comrade Colonel." The technician traced a finger on the TV screen. "This is Pamlico Sound, on the central coast of the United States. Look here, Comrade." The thermal image of the water on the screen was black, but as the technician adjusted the display it changed to green with two white patches, one larger than the other. Twice the large one split into two segments. The image was of the surface of the water, and some of the water was half a degree warmer than it should have been. The differential was not constant, but it did return enough to prove that something was adding heat to the water. "Sunlight, perhaps?" the colonel asked. "No, Comrade, the clear sky gives even sunlight to the entire area," the technician said quietly. He was always quiet when he thought he was on to something. "Two submarines, perhaps three, thirty meters under the water." "You are certain?" The technician flipped on a switch to display the radar picture, which showed only the corduroy pattern of small waves. "There is nothing on the water to generate this heat, Comrade Colonel. Therefore it must be something under the water. The time of year is wrong for mating whales. It can only be nuclear submarines, probably two, perhaps three. I speculate, Colonel, that the Americans have been sufficiently frightened by the deployment of our fleet to seek shelter for their missile submarines. Their missile sub base is only a few hundred kilometers south. Perhaps one of their Ohio-class boats have taken shelter here and is being protected by a hunter sub, as ours are." "Then he will soon move out. Our fleet is being recalled." "Too bad, it would be good to track him. This is a rare opportunity, Comrade Colonel." "Indeed. Well done, Comrade Academician." Ten minutes later the data had been transmitted to Moscow. Soviet Naval High Command, Moscow "We will make use of this opportunity, Comrade," Gorshkov said. "We are now recalling our fleet, and we will allow several submarines to remain behind to gather electronic intelligence. The Americans will probably lose several in the shuffle." "Quite likely," the chief of fleet operations said. "The Ohio will go south, probably to their submarine base at Charleston or Kings Bay. Or north to Norfolk. We have Konovalov at Norfolk, and Shabilikov off Charleston. Both will stay in place for several days, I think. We must do something right to show the politicians that we have a real navy. Being able to track on an Ohio would be a beginning." "I'll have the orders out in fifteen minutes, Comrade." The chief of operations thought this was a good idea. He had not liked the report of the Politburo meeting that he'd gotten from Gorshkov—though if Sergey were on his way out, he would be in a good place to take over the job... The New Jersey The RED ROCKET message had arrived in Eaton's hand only moments before: Moscow had just transmitted a lengthy operational letter via satellite to the Soviet fleet. Now the Russians were in a real fix, the commodore thought. Around them were three carrier battle groups—the Kennedy, America, and Nimitz—all under Josh Painter's command. Eaton had them in sight, and had operational control of the Tarawa to augment his own surface action group. The commodore turned his binoculars on the Kirov. "Commander, bring the group to battle stations." "Aye." The group operations officer lifted the tactical radio mike. "Blue Boys, this is Blue King. Amber Light, Amber Light, execute. Out." Eaton waited four seconds for the New Jersey's general quarters alarm to sound. The crew raced to their guns. "Range to Kirov?" "Thirty-seven thousand six hundred yards, sir. We've been sneaking in a laser range every few minutes. We're dialed in, sir," the group operations officer reported. "Main battery turrets are still loaded with sabots, and gunnery's been updating the solution every thirty seconds." A phone buzzed next to Eaton's command chair on the flag bridge. "Eaton." "All stations manned and ready, Commodore," the battleship's captain reported. Eaton looked at his stopwatch. "Well done, Captain. We've got the men drilled very well indeed." In the New Jersey's combat information center the numerical displays showed the exact range to the Kirov's mainmast. The logical first target is always the enemy flagship. The only question was how much punishment the Kirov could absorb—and what would kill her first, the gun rounds or the Tomahawk missiles. The important part, the gunnery officer had been saying for days, was to kill the Kirov before any aircraft could interfere. The New Jersey had never sunk a ship all on her own. Forty years was a long time to wait. "They're turning," the group operations officer said. "Yep, let's see how far." The Kirov's formation had been on a westerly course when the signal arrived. Every ship in the circular array turned to starboard, all together. Their turns stopped when they reached a heading of zero-four-zero. Eaton set his glasses down in the holder. "They're going home. Let's inform Washington and keep the men at stations for a while." Dulles International Airport The Soviets outdid themselves getting their men away from the United States. An Aeroflot Illyushin IL-62 was taken out of regular international service and sent directly from Moscow to Dulles. It landed at sunset. A near copy of the British VC-10, the four-engine aircraft taxied to the remotest service area for refueling. Along with some other passengers who did not deplane to stretch their legs, a spare flight crew was brought along so that the plane could immediately return home. A pair of mobile lounges drove from the terminal building two miles to the waiting aircraft. Inside them the crewmen of the Red October looked out at the snow-dusted countryside, knowing this was their final look at America. They were quiet, having been roused from bed in Bethes
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29212, 310, 3164, 4030, 323, 247, 21841, 273, 271, 19614, 19327, 1108, 533, 417, 594, 1199, 323, 1323, 279, 982, 390, 45056 ]	Wymagane', type: 'Typ', typeText: 'Tekst', typePass: 'Hasło', typeEmail: 'Email', typeSearch: 'Szukaj', typeTel: 'Numer telefonu', typeUrl: 'Adres URL' } } ); WE are familiar with the parable of the lost sheep that holds so many precious lessons for us. (cfr Lk 15,1-7) We should try to be that shepherd who was willing to leave behind 99 faithful sheep to look after the one who went astray and got lost. We can imagine what that shepherd went through to look for that sheep. For a sheep to get lost can mean that it went to another area where it and the other sheep should not go. And so the shepherd must have explored some unfamiliar places to find it. It’s not...If a design is taking too long then it’s the wrong design Elon Musk Everyday Astronaut Interview This is by far the topic I get the most push back from engineers about. Even more than Software Engineering is Writing. They always want to go slower, more carefully. The idea of doing what they’re doing now but faster seems crazy. It is crazy. You can’t go faster doing what you’re doing now. Instead I want us to change what we’re doing to go faster. Why should we be trying to go faster? In short, because we’re professionals. Professionals vs Hobbyist Activity Professional Hobbyist Driving 200 MPH 65 MPH Football QB decision to pass or run 3 sec 10 sec Cleaning a 1br Apartment 4 hr 1 day Baseball fastball 90 MPH 50 MPH Programming – implementing a single screen of a prototype UI 1 month 2-3 days An almost universal difference between a professional and a hobbyist in every job is speed. Professionals are faster than amateurs. Most of the above data comes from the book “Wait: The Art and Science of Delay” by Frank Partnoy. The title is an interesting choice as the main argument I get out of the book is: Focus on speed. Speed allows you to wait longer to take action. Waiting longer allows you to gather more information, which increases the likelihood of a better outcome. It reminds me of the Special Forces phrase: “Slow is smooth and smooth is fast”. The last line in the table comes from a friend at Google. They told me this is how long it takes them to make a single prototype screen for a UI. I nearly spit out my coffee. I chose this because the majority of programmers I talk with are Googlepheliacs who think everything they do is “the way” and should be emulated always, everywhere. Speed of what? If you want a metric, the one I’m currently using is: Working software, in the hands of customers, as quickly as possible with as low a defect rate as possible. Another valid approach might be something like: minimizing median time to feedback. But won’t quality suffer? No, I don’t believe so. It might at first, as people who are used to driving their car straight until they hit a guard rail realize they might actually have to learn how to drive. But on the whole I believe the quality of your programming skills increase faster with the quantity of finished products more than slow reasoned debate. If that’s true then the faster you build products, the faster your skills develop. The following story illustrates the impact of speed on quality: The ceramics teacher announced on opening day that he was dividing the class into two groups. All those on the left side of the studio, he said, would be graded solely on the quantity of work they produced, all those on the right solely on its quality. His procedure was simple: on the final day of class he would bring in his bathroom scales and weigh the work of the “quantity” group: fifty pounds of pots rated an “A”, forty pounds a “B”, and so on. Those being graded on “quality”, however, needed to produce only one pot – albeit a perfect one – to get an “A”. Well, came grading time and a curious fact emerged: the works of highest quality were all produced by the group being graded for quantity. It seems that while the “quantity” group was busily churning out piles of work – and learning from their mistakes – the “quality” group had sat theorizing about perfection, and in the end had little more to show for their efforts than grandiose theories and a pile of dead clay. “Art & Fear” by David Bayles & Ted Orland John Carmack approves in principle: Similar to above but more science: “Ok, I’m not gonna click on any of that, but how would you propose we accomplish this?” I hear you say. Well, I have some thoughts… Work on the problem in front of you Stop trying to predict the future (“future proofing systems”) and just solve the problem you’re trying to solve with the minimal amount of code necessary. The current approach is hurting in the following ways: We’re all bad at predicting the future, so what you write may never be necessary. It takes more time to write the future proof version of the code. Creating flexibility requires abstraction. This abstraction is implemented through indirection. Every layer of indirection adds cognitive load that is unnecessary and unrelated to the task (sometimes called incidental complexity). Good abstractions are difficult to make correctly and require lots of examples to do well. Repeat Yourself A little bit of code duplication is better than maintaining 20+ abstract types. — Jaana B. Dogan ? (@rakyll) February 12, 2020 gasp I use the Rule of 3: I will copy and paste the same code twice. Once there is a third concrete need for that same code, I then feel like I have enough information that the likelihood of creating the appropriate abstraction is high. Don’t Break Tools! Two years ago I quit my job and decided to strike out on my own. Since I was programming for myself, I thought there’s no harm in using a programming language I love and had used to great success in production elsewhere, and so I wrote everything in F#. I truly believe that F# is the best language on the .NET platform and has the superior programming model for eliminating entire categories of bugs (no null, for example). I believed the strong type checker would help me move more quickly than in C#. I was wrong, but not for the reason I originally thought. For the last 6 months I’ve moved back to C# for only one reason. Tooling. All of the tooling around C# really increases your productivity with the language despite some of the issues around null, verbosity around types, etc. in F# I had to write the simple database migrations myself or otherwise jump through hoops to have a single C# project linked to my F# project so that EF Core would do the magic. The same thing is true for writing mobile apps with Xamarin. The tooling for C# ‘just works’, while for F# there’s a lot of gotchas and edge cases that you need to figure out. The time to go from idea to working code either in the browser or on my mobile device is shorter with C# because of the tooling aiding me in writing correct robust code. So this has changed my language stack-rank. I’ve found it’s preferable to use the ones with the best tools. Modern IDEs, debuggers, profilers, static analysis tools all help you immensely to speed up the time it takes to write correct, robust code. If you’re not using them, then you don’t even know what you’re missing. I like VIM as much as the next person, but it doesn’t hold a candle to Visual Studio or IntelliJ in terms of productivity. Yet in almost every large project I’ve worked on, no matter the language, someone has broken the tooling. Usually the culprit is the build. They’ve put things in non-standard directories and then write their own build script to re-assemble everything in the correct place for CI… but I wish they had just taken the time to get it working for everyday developers in the standard tool. Testing and Other Quality Control I’ve heard arguments from the TDD crowd that although testing requires more upfront work it actually makes you go faster. This is not born out by the evidence in the book “Making Software: What Really Works, and Why We Believe It” by Andy Oram, Greg Wilson which is as close as I’ve been able to find to someone using the scientific method to measure things about software engineering processes. You can quibble about the testing methodologies of the underlying papers, but it’s still peer reviewed and published data, which is better than any blog post, including this one. Testing absolutely helps when a project is so large you can’t keep it all in your head, but it’s not an unalloyed good. Testing makes permanent. Maybe that’s what you want, but maybe it’s not. How can we tell the difference? A maturity model of software is useful here. A Maturity Model of Software I think it’s obvious on its face that not all software is created equal. Software that crashes is probably fine for a prototype of an Instagram clone – but not so much for avionics or automobiles
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Unlike photons, whose intensity decreases in an approximately exponential fashion within the patient, electrons deposit most of their dose within a fixed, finite range which depends on the energy of the beam. Thus, a single electron beam can be used to treat superficial lesions while sparing underlying healthy tissues. Electron treatments are delivered with electron cones of various sizes and shapes that are typically attached to the collimator of a linear accelerator, and which shape the electron beam very close to the patient surface. The shapes can be standard geometric shapes, such as circles or squares of various sizes, or an arbitrary shape can be custom-made for a given patient. In some instances, a lead sheet having an opening that defines the aperture of the beam is placed directly on the patient's skin. Electron treatments are usually planned with a fixed source-to-skin distance (SSD). Breast boosts (a radiotherapy treatment in which a “boost” of 10-16 Gy of radiotherapy is given in addition to the normal radiotherapy treatment after surgery) typically use an SSD of 100 cm, as this is the same distance from the beam source to the isocenter of most linear accelerators (“linacs”). As a result, the linac isocenter, and hence the intersection of any wall lasers being used to align the patient with the linac, lies on the patient skin surface. This is in contrast to many photon treatments, which are planned such that the isocenter is near the center of the treatment volume. For a breast boost, the electron field ideally should cover the tumor bed and the surgical path leading from the tumor bed to the surgical scar, plus a 1-2 cm margin. In addition, it is preferable to avoid the areola. Unfortunately, the location of the scar, which is used often as a proxy for the lumpectomy site to aim the electron beam, is often a poor indicator of the actual location of the underlying tumor bed. Ultrasound has been used for planning purposes to obtain the size and shape of the tumor bed, or seroma, which is the fluid-filled region of the lumpectomy site. Surgical clips, placed during surgery around the lumpectomy site, are radio-opaque and have also been used as a proxy for the lumpectomy site for planning purposes. What is needed, however, is a methodology to incorporate internal information, e.g., the position and extent of seroma as observed in ultrasound images, into the conventional clinical setups (simulation and/or treatment) for electron breast boost treatments.This invention relates to metal complexes and to addition polymerization catalysts formed therefrom that have improved catalytic performance. More particularly the present invention relates to an addition polymerization catalyst composition comprising a Group 3, 4, or Lanthanide metal complex containing a boratabenzene group or divalent derivative thereof bonded via its delocalized xcfx80 electrons to the metal (also referred to as a boracyclohexadienyl group). In addition, the present invention relates to certain of the foregoing complexes possessing a novel bridged structure. Finally, the invention relates to a method of using the foregoing catalyst compositions in an addition polymerization process for polymerizing addition polymerizable monomers. In EP-A-416,815 there are disclosed certain constrained geometry metal complexes and catalysts derived by reacting the metal complex with activating cocatalysts. Supported derivatives of such catalysts were prepared by contacting them with a support such as alumina, silica or MgCl2. In U.S. Pat. No. 5,064,802 (EP-A-418,044) there are disclosed certain further catalysts formed by reacting metal complexes with ion forming activating cocatalysts that are salts of Bronsted acids containing a non-coordinating compatible anion. The reference discloses the fact that such complexes are usefully employed as catalysts in addition polymerizations. In EP-A-520,732 an alternative technique for preparing cationic constrained geometry catalysts using borane activators is disclosed. In U.S. Pat. No. 4,892,851 there are disclosed biscyclopentadienyl Group 4 metal complexes, especially complexes of zirconium or hafnium that are usefully employed with alumoxane activating cocatalysts for use in addition polymerizations, especially the polymerization of aliphatic xcex1-olefins. In a series of patents, W. Spaelick has disclosed certain ring substituted stereorigid bisindenyl complexes and their use as olefin polymerization catalysts. The bridging group of such complexes generically includes silicon, germanium or tin containing divalent groups containing hydride, halogen, C1-10 alkyl, C6-10 fluoroalkyl, C6-10 aryl, C6-10 fluoroaryl, C1-10 alkoxy, C2-10 alkenyl, C7-40 aralkyl, C8-40 aralkenyl or C7-40 alkylaryl groups or ring forming combinations thereof. Such disclosure may be found in U.S. Pat. No. 5,243,001, U.S. Pat. No. 5,145,819, U.S. Pat. No. 5,304,614, U.S. Pat. No. 5,350,817, among others. Boratabenzenes are anionic ligands which are boron containing six membered ring systems. They are previously known in the art having been described by A. Ashe, et al., J. Am. Chem. Soc., 93, 1804-1805 (1971). They may be prepared by reaction of 1,1-diorgano-1-stannacyclohexa-2,5-diene and a borontrihalide followed by substitution with a hydrocarbyl, amino, silyl or germyl group. Such ligand groups correspond to the formula: wherein J is selected from the group consisting of hydrogen, hydrocarbyl, dihydrocarbylamino, silyl, germyl, halohydrocarbyl, or halocarbyl, said J having up to 20 non-hydrogen atoms. It would be desirable if there were provided an improved catalyst system based on the foregoing boratabenzene groups as well as an improved addition polymerization process utilizing such catalyst systems. As a result of investigations carried out by the present inventors there have now been discovered new and improved Group 3, 4, or Lanthanide metal complexes corresponding to the formula: or a dimer, solvated adduct, chelated derivative or mixture thereof, wherein: Y is a divalent derivative of a boratabenzene group or a hydrocarbyl-, dihydrocarbylamino-, silyl- or germyl-substituted boratabenzene group containing up to 50 nonhydrogen atoms that is bonded via its delocalized xcfx80-electrons to M; L is Y or a hydrocarbadiyl group that is bound to M by means of its delocalized xcfx80-electrons, or L is a monovalent or divalent amido group, said L group containing up to 50 nonhydrogen atoms; M is a metal of Group 3, 4 or the Lanthanide series of the Periodic Table of the Elements; Z is a covalently bound, divalent substituent of up to 50 non-hydrogen atoms having the formula, xe2x80x94(ER22)mxe2x80x94, wherein E independently each occurrence is carbon, silicon or germanium, R2 independently each occurrence is selected from the group consisting of hydrocarbyl, hydrocarbyloxy, silyl, and germyl of up to 20 atoms other than hydrogen, and m is an integer from 1 to 3; Xxe2x80x2 is a neutral ligand having up to 20 non-hydrogen atoms; Xxe2x80x3 independently each occurrence is a monovalent, anionic moiety selected from hydride, halo, hydrocarbyl, silyl, germyl, hydrocarbyloxy, dihydrocarbylamide, siloxy, halohydrocarbyl, halosilyl, silylhydrocarbyl, and dihydrocarbylaminohydrocarbyl having up to 20 non-hydrogen atoms, or two Xxe2x80x3 groups together form a divalent hydrocarbadiyl group; n is a number from 0 to 3; and p is an integer from 0 to 2. According to the present invention there are further provided improved addition polymerization catalyst compositions comprising an activating cocatalyst and one or more Group 3, 4 or Lanthanide metal complexes corresponding to the formula: or a dimer, solvated adduct, chelated derivative or mixture thereof, wherein: Yxe2x80x2 is a boratabenzene group or a hydrocarbyl-, dihydrocarbylamino-, silyl- or germyl-substituted boratabenzene group containing up to 50 nonhydrogen atoms that is bonded via its delocalized xcfx80-electrons to M; Lxe2x80x2 is Yxe2x80x2 or a hydrocarbyl group that is bound to M by means of its delocalized xcfx80-electrons, or Lxe2x80x2 is an amido group, said Lxe2x80x2 group containing up to 50 nonhydrogen atoms; L and Y are as previously defined; M is a metal of Group 3, 4 or the Lanthanide series of the Periodic Table of the Elements; Z is a covalently bound, divalent substituent of up to 50 non-hydrogen atoms having the formula,
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313, 33856, 281, 1722, 361, 10, 20029, 1253, 15882, 28, 13986, 7466, 21807, 1253, 15882, 28, 5284, 16136, 2246, 21043, 28, 24084, 434, 11947, 20986, 21807, 28, 11947, 15050, 13, 24520, 27933, 8073, 1253, 3439, 13, 6705, 187, 187, 14463, 39226, 5209, 13, 378, 15, 273, 313, 1093, 1762, 10, 25098, 187, 187, 14463, 17551, 313, 4185, 1253, 12231, 10, 10909 ]	Poniatowski, king of Poland 202, 203 Stanley, H. M. 254 Starya Ladoga, Russia 113 Staufen emperors 109 steam power 206 steamships, development of 229, 263–264 steel output 220 Stephen, king of Hungary (997–1038) 98, 101 Strategic Arms Limitation Treaty (SALT) (1972) 293, 325 Stuttgart, Germany 196 Su-chou, China 166 Sudan 135; British conquest of 258; British reconquest of 255; civil war in 316; Nile valley 15; war in 309, 311, 312 Sudan, Nilotic 252 "Sudanic belt" 134, 135 Sudetenland 282 Sueves 85 Suez, Egypt 167; canal 152, 246; invasion (1956) 295 Su. saints 128 sugar, cane 152, 181 sugar trade 203, 204 Suhar, Yemen 87 Suharto, President 301, 304 Sui dynasty (581–618) 65, 67, 117 suicide bombers, Muslim xxviii–xxix, 340 suicide ( _kamikaze_ ) pilots 285 Sukarno, Achmed 274, 300–301 Sukarnoputri, Megawati 304 Sukhothai, kingdom 130 Suleiman the Magnificent (1520–66) 138, 167, 168 Sultaniya, Azerbaijan 120 Sumatra 5, 180 Sumerian civilization xxxi Sumerian language 31 Sumitomo family 177 Sun Yat-sen 245, 274, 275 Sunda shelf 23 Sung dynasty 66, 117, 118–119 Sung-chiang, China 166 Sunni Ali, king of Songhay 135, 163 Sunni Muslims xxx, 169, 316, 339 Sunni Seljuk Turks 131, 132, 133 Superior, Lake 229 Suppiluliuma (1344–1322 BC) 34 Surat, India 157 Susa, Mesopotamia 30, 31 Susilo Bambang Yudhoyono 304 Sven, king of Denmark 100 Svyatoslav, Grand Prince ( _c_. 962–72) 107 Svyatoslavich, Vladimir (980–1015) 107 Swahili-Arabs 252 Sweden: 900 to 1050 100; Baltic empire 192–193; breaks away from Scandinavian Union 192; power, decline of 194; wars with Denmark (1643–5, 1657, 1658, 1676–9) 193, 194 Swedes 99, 108 Swedish migrants 233 Swiss Confederation 141 Swiss migrants 233 Syria 33, 55, 87–88, 132, 272 "Syrian jugglers" 53 Szechwan, tribal risings in (1746–9, 1771–6) 172 Tabon Cave, Palawan 20 Tabriz, Iran 120, 122 Tahiti 258 T'ai-p'ing rebellion 244 Taika revolution (645) 115 Taino people 37, 145, 146 Taira clan 116 Taiwan (Formosa) 256, 259, 277; early cultures in 41; since 1945 296, 297 Taj Mahal, India 171 Tajikistan 120 Takauji, Ashikaga 116, 117 Taliban 308, 338 _Talmud_ (ad 500) 93 Tamerlane (Timur) 120–121, 124, 128, 137, 170; followers of 119 Tamil Tigers (LTTE) 307 Tamils 307 T'ang Chinese armies 115 T'ang dynasty 43, 117–118 Tanganyika 254, 260, 272 Tanganyika, Lake 252 Tangier 191 Tanguts 118 Tannenberg, B. of (1914) 266 Tanzania, "Ujamaa" policies 310 Tanzimat reforms 240–241 Taoism xxii Tapajós chiefdom 144 Taranaki, New Zealand 250 Taranto, Italy 97 Tarim Basin 118 Tariq ibn Ziyad 89 Tashkent 170 Tasmania (Van Diemen's Land) 248 Tatar Chin 119 Tatar invasions xxxiv Taxila 69 tea trade 205 technologies: development of xxxi–xxxii, xxxv–xxxvi; early 3; Western, export of xxxviii Teheran conference (1943) 287 Tehran, Iran 169 telecommunications 344–345 telegraph service, US 227–228 telephone, invention of 343 Tell 'Uqair, Mesopotamia 30 Templars 103 temples: Central Andes 19; early 13 Tenasserim 180 Tenedos 201 Tennessee River 232 Tenochtitlán xxxv, 145, 146 Teotihuacán, Mesoamerica 38 Ternate 131, 156 terror, rise of, and religion 340 "terror, war on" 326, 335 terrorism, world, since 1945 335–337; and nation-building 336; and social revolution 336–337 Tertry, B. of (687) 95 Teutonic Knights 104, 108, 140 Teutonic Order 192 Texas 160 Texcoco, Lake 145 textile industry 206, 219, 229 Thailand: 1954 to 1975 301; since 1975; Buddhist shrines in 129; early man in 20, 21; French in 179; military coup (2006) 305 Tham Khuong, Vietnam 20 Thebes, Egypt 33, 55, 60 Theodoric 86 Theodosius 81 Thera, volcano 48 Theravada Buddhism 131; teachings 68–69 Thessaly 61, 106 Third Department 242 Thirteen Years' War (1654–67) 158 Thirty Years' War (1618–48) 93, 191, 193, 194, 195 Thomson, Joseph 343 Thorn, burghers rebellion 192 Thorn, Peace of (1466) 192 Thrace 61, 85, 106 Three Feudatories, rebellion of (1674–81) 172 Thucydides 60 Ti people 66 Tiahuanaco, Bolivia 36 Tiber, River 73 Tiberius (14–37) 76 Tibet 275 Tidore 131 Tiglath-pileser III (744–727 BC) 55 Tigris valley, lower 27, 28, 30 Tikulti-ninurta I (1233–1197 BC) 35 Tilsit, Treaty of (1807) 213 Timbuktu, Niger 135, 163 "Time of Troubles" (1605–13) 158 Timur _see_ Tamerlane Tipu Sultan 171, 209 Titicaca Basin, Bolivia 36 Tito, Marshal 290 Titus (79–81) 76 Tlatelolco 145 Toba volcano, Sumatra 5 tobacco 152; trade 203, 204 Tocharians 57 Togoland 254, 272 Tokugawa Ieyasu 176 Tokugawa Shogunate xxxvii, 176–178 Toltecs, rise of the 38–39 Tongan region 24 tools, early xxxi, 3, 22, 15; Asian 20 Tordesillas, Treaty of (1494) 154, 162 Toronto, Canada 236 Toul 197 Toulouse, France 85 Toungoo, Myanmar 130 Touraine 111 Tournai, France 95 Toxandria 85 Toynbee, Arnold: _A Study of History_ xviii Toyotomi Hideyoshi (1536–98) 176 trade, Baltic 192 trade, global ( _c_. 1775) 203–205; Asia, trade with 205; mercantilism 203–204; slave economy 204–205; and "triangular" 152, 203, 204 trade, Neolithic 12–13 "trade diasporas" 53 trading, early, in Eurasia 29, 30–31 trading empires, expansion of (1500 to 1700) 155–157; Dutch expansion 156–157; European rivalries 157; Portugal's trading empire 156; trading routes, Eurasian 52–54, 64 Trafalgar, B. of (1805) 213 Trajan (98–117) 76
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]	ed of just a window? :-) <louise> how do I install the driver for a 802.11b/g wireless network card, in ubuntu ? <werdnum> Hi! When I resume from suspend, my screen goes bananas and I have to alt-sysrq-K to get back to a sensible X terminal <werdnum> s/terminal/session/ <ardchoille> stian: right click the workspace switcher and choose Preferences <stian> Yes but preferences isent there (?) <DawnLight> quanta+ is not develoed anymore, is it? <stian> Can adjust how many workspaces i want, thats it. <Rec0> ehm could someone help me i've got a fresh ubuntu installed but it doesn't load it says grub error 2 <Rec0> i've got multiple hdd's in my pc (3 and a dvd-burner) <Slart> stian: it seems there used to be a checkbox for this.. there is still a variable in gconf-editor for it <richard> greetings, and merry christmas <Guest29648> i have a problem with the amsn audio and video <Guest29648> can someone help, i am using intrepid <stian> Slart: Will take a look :-) Thanx <shoeunited> I've found a solution to a "screenshot gallery of a movie" that has been plauging some users for a long time. Where should I make a topic for it? <crow> is there already .dev package for mplayer_vdpau to test? <shoeunited> In the forums, I mean. <Slart> stian: seems it only works if you're running metacity though =/ <Guest29648> i have a problem with the amsn audio and video <Guest29648> no audio and video <stian> Running the same ubuntu on the laptop and there i have given them names.... but here i just cant find it.. <richard> i have a problem with the amsn audio and video <richard> no audio and video <Guest11676> help please <FiremanEd> !ask \| Guest11676 <ubottu> Guest11676: Please don't ask to ask a question, simply ask the question (all on ONE line, so others can read and follow it easily). If anyone knows the answer they will most likely reply. :-) <Guest11676> well i try to call someone with amsn but it say something about /dev/dsp <man> hello <man> can you help me? <FiremanEd> !ask \| man <ubottu> man: Please don't ask to ask a question, simply ask the question (all on ONE line, so others can read and follow it easily). If anyone knows the answer they will most likely reply. :-) <Guest11676> ok <eleos2> what is the shortcut of changing the language <eleos2> ? <PurplePlus> eleos2 alt+shift doesn't work? <eleos2> purpleplus no <man> allo <ardchoille> PurplePlus: alt+shift brings up the window menu bydefault <bitsbam> hey all, is there a way when i share a drive ( either with samba or nfs, don't care which ) that i can make 2 drives appear as one to the client computer? I guess i am looking for a program that will do this. <bartek> hi, I keep getting Could not get lock /var/lib/dpkg/lock - open (11 Resource temporarily unavailable) .. It's because I have a "aptitude search w" running in my ps but how can I kill it? I've tried sudo kill <pid> and kilall aptitude but no luck it just sits there. Any tips? <melch> Hey can someone help me install adobe air on a 64 bit install? <joaopinto> bitsbam, sure, just make sure those drives are mounted inside your share path <joaopinto> !aptlock \| bartek <ubottu> bartek: If an APT front-end crashed and your database is locked, try this in a !terminal: Â« sudo fuser -vki /var/lib/dpkg/lock;sudo dpkg --configure -a Â» <bartek> What does that do before I run it? <bartek> brief summary :-) <gauravkumar> tryin to install warcraft III on hardy.. i have a dell inspiron 1525 .. intel 965 video .. i get a black screen when i run with wine and nothin else... any help? <joaopinto> bartek, it kills the process locking that file <mint_> hi guys, i have a problem with java, everytime i try to use a digital certificate with java, it show me a pop up to select it, but there's no certificate (and i've already imported it), any suggestion? <error404notfound> I am in single user mode, I have /,/var,/boot,/var/www and I want to run fsck on them but it says that they are mounted, when I try to unmount them ubuntu cries about them being busy <bartek> ok <bartek> thanks <eleos2> what is the keyboard shortcut of changing the default language <eleos2> ? <joaopinto> !wine \| gauravkumar <ubottu> gauravkumar: WINE is a compatibility layer for running Windows programs on GNU/Linux - More information: https://help.ubuntu.com/community/Wine - Search the !AppDB for application compatibility ratings - Join #winehq for application help <bartek> awesome .. thanks joaopinto ! <melch> !adobe air <ubottu> Sorry, I don't know anything about adobe air <joaopinto> eleos2, I am not aware of a shortcut for that, it's available from System -> Admin -> Lang Support <kanibalizm> gosh <kanibalizm> so many ppl <joaopinto> error404notfound, are you sure you booted in recovery mode ? Have you untried to unmount them ? <kanibalizm> who can help about UBUNTU :) <joaopinto> !anyone \| kanibalizm <ubottu> kanibalizm: A large amount of the first questions asked in this channel start with "Does anyone/anybody..." Why not ask your next question (the real one) and find out? <em123> hi, please tell me one livecd that have these 3 feature, 1, minimal, 2, make, gcc, 3, after startup, the livecd can been pull out and put another cd into cdrom drive <error404notfound> joaopinto: I am in recovery mood, from there I select root shell option, I have also tried to unmount them... <kanibalizm> shoul id ask in channel :) <joaopinto> em123, the ubuntu live cd does not allow that <joaopinto> !ot \| em123 <ubottu> em123: #ubuntu is the Ubuntu support channel, for all Ubuntu-related support questions. Please use #ubuntu-offtopic for other topics. Thanks! <gauravkumar> joaopinto: i did install through wine and finally when i try to run the exe i get a black blank screen.. also noteworthy.. i get direct rendering: No (LIBGL_ALWAYS_INDIRECT set) from glxinfo <melch> Anyone have any info on adobe air and ubuntu <em123> ok <joaopinto> gauravkumar, "direct rendering: No" means you are not using the 3d capable drivers <joaopinto> gauravkumar, System -> Admin -> Hardware drivers <simon_> hi. since upgrade/update I get I/O errors with my cdrom drive (only with audio disc, not with data cds) <joaopinto> check if there is a recognized proprietary drivers for your card <kanibalizm> This is a major failure of your software management system. Please check for broken packages with synaptic, check the file permissions and correctness of the file '/etc/apt/sources.list' and reload the software information with: 'sudo apt-get update' and 'sudo apt-get install -f'. <kanibalizm> this i what i have :) <joaopinto> kanibalizm, on the terimnal run: sudo apt-get install -f <kanibalizm> jabagawee you can help ? <joaopinto> as suggested by the message <gauravkumar> joaopinto: Hardware drivers doesnt list anything.. tried to get something relevant by using envy but this is an intel chipset and envy is for nvidia and ati <ardchoille> joaopinto: I have a vid card and after installing ubuntu direct rendering says yes, but the 3d drivers are not installed. I don't think direct rendering means 3d capable <joa
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Snitch. Rat. Job loss and ruptured relationships are common consequences; so is grief over the loss of a once-shared identity. Whistleblowing can end with ignominy, imprisonment or exile. Sometimes it is a secret carried to the grave, or nearly so. “I didn’t, I couldn’t, even use that word about myself — whistleblower,” said Jacqueline Garrick, 56, the founding director of a Department of Defense suicide prevention program who said she ran afoul of Pentagon officials when she raised still-contested allegations, first internally and then publicly, of fraud and abuse. A former Army officer, Garrick likened her experience in the three years since she came forward to the post-traumatic stress sometimes suffered by combat veterans — sleeplessness and anxiety, isolation and despair. She went on to found a peer-support group, Whistleblowers of America, to help others deal with the psychological and practical consequences of making accusations of workplace wrongdoing. “You just don’t realize at first,” she said, “that your life is never going to be the same.” :: The whistleblower at the center of the Trump impeachment inquiry, reportedly a CIA analyst temporarily assigned to the White House, probably had a better sense than most of what might lie ahead. The individual’s complaint, filed Aug. 12, landed like a bombshell in official Washington when the House Intelligence Committee made it public on Sept. 26. Except for two blacked-out paragraphs in a classified appendix, the nine-page document spelled out in crisp, measured prose the writer’s belief that Trump was “using the power of his office to solicit interference from a foreign country in the 2020 U.S. election.” Acting Director of National Intelligence Joseph Maguire said the whistleblower who came forward in August with a complaint about President Trump’s dealings with Ukraine followed the required steps in reporting such concerns. (Kirk McKoy / Los Angeles Times) The acting director of national intelligence, Joseph Maguire, told lawmakers that the whistleblower had followed the law “every step of the way” in submitting it to the intelligence community’s inspector general. Disclosure of the complaint prompted a response familiar in the annals of whistleblowing: attack the messenger. The president denounced the whistleblower as a “partisan hack,” a “Deep State” operative, “close to a spy,” a betrayer of trust. Trump said the whistleblower should be unmasked — contrary to legal guarantees of anonymity — and demanded to personally confront his accuser. Although federal rules do not require a whistleblower’s information be firsthand, the president seized on the fact that the complainant acknowledged not having heard Trump’s crucial July 25 telephone call with Ukrainian President Volodymyr Zelensky, when Trump pressured the new leader to investigate his political rival, Joe Biden. But the declassified White House memorandum of the call, essentially a rough transcript, appeared to confirm large parts of the whistleblower’s complaint. President Trump has attacked the Ukraine whistleblower allegations. (Win McNamee / Getty Images) Lawyers representing the whistleblower said over the weekend that a second individual had come forward, also from the intelligence community. That is also a well-worn whistleblower scenario — especially if the second individual brings firsthand knowledge that could bolster the original complaint. On Sunday, 90 former national security officials — with service under both Republican and Democratic presidents — released an open letter calling for privacy and protection from retaliation for the person whose complaint set the impeachment inquiry in motion. “A responsible whistleblower makes all Americans safer,” they wrote. :: The term “whistleblower” is of uncertain origin, thought to refer to a police officer’s response when spotting a criminal, or to a sports referee calling out a foul. But most researchers say its animating principle dates to medieval times, with recognition of the right of individuals, not only officialdom, to sound the alarm about wrongdoing. In English common law, the writ of qui tam meant a private individual who assisted in an official prosecution was entitled to a share of the penalty paid. So it carried a connotation of bounty hunting, when a person was acting “for the king as well as for self.” Richard Nixon resigned as president in 1974 amid the Watergate investigation, which was fed in part by a whistleblower then known as “Deep Throat.” (Associated Press) In the United States, the term “whistleblower” only came into wide use around 1975, with headline-grabbing cases such as the Pentagon Papers, which exposed White House deceit in the Vietnam War, the Watergate scandal that brought down President Nixon, and the work of crusading of consumer advocate Ralph Nader. Stanger’s book, “Whistleblowers: Honesty in America From Washington to Trump,” details the case of the Revolutionary War seamen who won the legal protection of the Continental Congress when their wealthy and well-connected commodore, Esek Hopkins, sought to retaliate against them for reporting him. The Civil War ushered in incentives for exposing graft associated with the procurement of military supplies. In modern times, landmark legislation included the Whistleblower Protection Act of 1989 and several major updates in the following three decades. But advocates say federal workers, and especially members of the intelligence community, still lack sufficient protections if they expose wrongdoing. “To truly protect whistleblowers, there’s a lot of unfinished business,” said David Colapinto, general counsel for the National Whistleblower Center. :: Al Pacino portrays Frank Serpico in the 1973 movie “Serpico.” The New York police officer exposed corruption in the NYPD. The real Frank Serpico, right, with his attorney, Ramsey Clark, testifies before the Knapp Commission investigating police corruption in 1971. Serpico, who helped clean up the NYPD, became a pariah among his former co-workers. (Associated Press) The Hollywood image of a feisty firebrand spoiling for a fight is rarely reflected in reality, according to Tom Mueller, who said he interviewed 200 whistleblowers for his book on the subject. Many whistleblowers believe their own organization will fix whatever wrong they brought to light, and are shocked and disillusioned when that doesn’t happen. And although a few may be disgruntled employees — another popular assumption that clings to whistleblowers — many more are motivated by personal values, Mueller said. Elin Baklid-Kunz said her upbringing in Norway, with its societal emphasis on equality and the common interest, led her to complain of serious financial misconduct at the Florida hospital where she worked, including overbilling Medicare and paying kickbacks. “I just wasn’t raised to think I was better than anyone else, or to think it was all right to take advantage of others,” said Baklid-Kunz, who appeared with Mueller at a recent panel on whistleblowing at a Washington bookstore. The crowd groaned at the description of hospital officials performing a bizarre “money dance,” with rap lyrics and costumes festooned with dollar signs, to convey the message that extracting cash, not patient care, was the top priority. Mueller’s book, “Crisis of Conscience: Whistleblowing in an Age of Fraud,” takes a Martin Luther King Jr. quotation as its epigraph — reflecting, he said, a worldview that many who blow the whistle finally, reluctantly, take to heart. “A time comes,” the civil rights icon told a New York City congregation in 1967, the year before his assassination in Memphis, “when silence is betrayal.”Alan Park survived cancer by using cannabis oil. He talks to us about it, his journey and his new podcast “Green Crush”. Why is Cannabis illegal? All questions answered on the Fringe. BRV, Bin Hamin, Josh Cory Host. ... William Ramsy joins us to discuss the prophet of Evil Aleister Crowley and how he has influenced pop culture. Crowley is the prophet of the Elite Religion. What are the Crowlian connections to Pizza gate? Was 911 a magic ritual sacrifice? Is Jay – Z a follower of the Crowley doctrine? BRV, Bin Hamin and... Richard Gage of Architects and Engineers for 911 Truth joins the fringe to discuss his activities on Seot 11th 2017 and review the evidence for the Implosion of the Twin Towers and Building 7 on September 11th 2001.Jimmy Gene of Enter the Microcosm joins us at the beginning of the hour to discuss our 911... PLANET X ARRIVES OCTOBER 2017? With David Meade aka The Profit of DOOM!! It’s supposed to happen according to him! Lets hope not. Do your own research!! We get into Biblical Prophecy and the signs in the skies that indicate planet X is on the way.. David Meade joins us to discuss. Josh Cory, Bin... THE VIEWS AND OPINIONS EXPRESSED ON THIS STATION BELONG SOLELY TO THOSE WHO MAKE THEM AND DO NOT NECESSARILY REFLECT THE VIEWS AND OPINIONS OF TRUTH FREQUENCY RADIO, iHeartRadio, OR OUR AFFILIATES / ADVERTISERS.Can Aging Develop as an Adaptation to Optimize Natural Selection? (Application of Computer Modeling for Searching Conditions When the "Fable of Hares" Can Explain the Evolution of A
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14924, 2281, 13, 10159, 273, 8645, 428, 533, 368, 878, 187, 936, 320, 2119, 368, 476, 1335, 12129, 1175, 9183, 432, 3076, 9183, 13, 594, 187, 5658, 476, 626, 816, 15331, 731, 7094, 15, 187, 187, 2598, 326, 5644, 441, 281, 253, 4499, 875, 1127, 1852, 20, 13, 1053, 626, 2406, 20252, 187, 1676, 2196, 13, 285, 253, 6452, 428, 247, 1332, 273, 2820, 281, 755, 1805, 1543, 432, 187, 43408, 2793, 6095, 672, 20252, 15, 27669, 1175, 1543, 432, 1679, 187, 38835, 310, 7964, 1633, 1774, 285, 4217, 13, 533, 1679, 2793, 187, 14, 261, 14, 247, 2406, 2629, 13, 594, 309, 1158, 253, 954, 4722, 9400, 310, 627, 15, 1680, 187, 13060, 272, 952, 275, 48109, 2143, 1663, 2217, 273, 271, 4503, 6081, 2429, 281, 187, 10526, 273, 2793, 32, 1359, 1057, 352, 7277, 281, 3515, 271, 4184, 390, 820, 14, 412, 187, 14996, 32, 1680, 627, 667, 1895, 342, 253, 24834, 38287, 2970, 10166, 327, 187, 38, 1641, 90, 434, 277, 553, 533, 2444, 323, 247, 32048, 32, 1359, 310, 48109, 2143, 187, 19623, 16, 29266, 685, 2444, 342, 247, 1980, 9835, 32, 187, 187, 6223, 187, 10629, 2211, 187, 3, 28240, 1135, 7551, 8645, 44720, 449, 659, 456, 671, 347, 346, 30436, 621, 1754, 327, 187, 38835, 449, 187, 187, 34214, 4360, 671, 346, 30436, 621, 1754, 327, 2793, 326, 17343, 581, 434, 13919, 187, 527, 22947, 83, 1515, 275, 40241, 40122, 285, 3103, 17337, 11216, 1345, 33728, 318, 449, 187, 187, 6223, 187, 39923, 5432, 187, 510, 7936, 1895, 342, 954, 44720, 310, 326, 627, 310, 3839, 1199, 187, 3062, 1491, 2130, 407, 7004, 253, 2060, 15, 187, 187, 909, 15, 7820, 273, 7384, 2255, 403, 625, 11518, 13, 816, 1642, 253, 795, 68, 33524, 64, 187, 13, 1642, 3533, 8704, 616, 2495, 6222, 15, 187, 187, 2512, 403, 1270, 5657, 581, 476, 897, 432, 253, 15065, 4491, 281, 2939, 271, 187, 27276, 84, 2495, 6222, 285, 40637, 271, 8410, 5522, 326, 16382, 616, 187, 14729, 15, 3808, 9183, 751, 4266, 313, 66, 5599, 10, 971, 625, 673, 745, 984, 359, 1871, 187, 30786, 6947, 673, 342, 2021, 685, 12425, 15, 187, 187, 2042, 368, 476, 2794, 247, 27846, 789, 3126, 368, 1833, 452, 642, 1895, 187, 1595, 25031, 12816, 326, 434, 11117, 13, 3185, 273, 816, 247, 12190, 273, 952, 665, 751, 187, 936, 789, 5096, 3038, 247, 2129, 15, 187, 187, 2042, 368, 3959, 581, 1979, 13840, 512, 8410, 368, 588, 16263, 952, 760, 323, 665, 187, 3529, 1979, 13840, 15, 1310, 368, 3959, 6290, 81, 3136, 8410, 368, 1833, 16263, 6290, 81, 3136, 187, 27276, 84, 15, 187, 187, 6223, 187, 10629, 2211, 187, 688, 247, 1533, 273, 3962, 1491, 13, 326, 651, 789, 15, 496, 247, 26812, 1533, 187, 9, 2108, 582, 352, 2506, 626, 789, 15, 187, 187, 27128, 326, 368, 452, 767, 3510, 273, 5261, 18145, 13, 26706, 329, 285, 26706, 378, 15, 6295, 452, 187, 85, 15740, 1972, 326, 2965, 2112, 253, 1072, 2622, 3268, 533, 342, 1027, 187, 30799, 15, 380, 1599, 323, 26706, 329, 310, 745, 407, 470, 15, 18, 2188, 13, 285, 253, 1599, 323, 26706, 378, 310, 745, 187, 1615, 470, 15, 19, 5823, 15, 187, 187, 4125, 13, 1333, 326, 368, 2557, 1016, 26706, 1078, 18738, 352, 13, 970, 247, 3962, 187, 28025, 981, 1159, 15, 496, 436, 1083, 13, 352, 2506, 626, 2647, 1880, 368, 897, 26706, 329, 187, 263, 26706, 378, 15, 187, 187, 6436, 13, 275, 253, 1524, 1533, 13, 368, 452, 271, 35180, 10499, 1159, 15, 21882, 326, 187, 262, 4245, 368, 271, 3662, 2112, 247, 2622, 3268, 342, 690, 2629, 187, 3620, 2492, 15, 187, 187, 10795, 436, 1056, 253, 1083, 323, 26706, 329, 390, 26706, 378, 1027, 32, 6279, 13, 368, 1833, 452, 187, 3062, 5261, 18145, 2965, 1561, 8150, 1972, 604, 368, 760, 897, 26706, 329, 15, 187, 187, 1992, 2007, 3157, 253, 1566, 13, 368, 651, 971, 281, 871, 253, 18235, 2105, 273, 187, 5302, 271, 30833, 25180, 26706, 285, 253, 6186, 14, 36478, 4815, 3206, 275, 760, 187, 5302, 5261, 18145, 273, 1511, 329, 15, 380, 1543, 273, 253, 13757, 1895, 651, 2028, 187, 5658, 849, 1199, 273, 26706, 329, 7147, 26706, 378, 281, 897, 15, 187, 187, 4485, 187, 73, 48079, 187, 4374, 13, 9991, 310, 1774, 15, 187, 187, 6436, 13, 604, 368, 403, 1512, 7106, 327, 20252, 5343, 19414, 13, 368, 476, 3324, 253, 187, 1189, 455, 3290, 273, 253, 2285, 1066, 15, 3954, 309, 513, 417, 1599, 5343, 19414, 403, 667, 187, 1417, 20566, 2429, 281, 5086, 19414, 13, 533, 309, 588, 1918, 271, 1650, 432, 187, 21941, 2793, 15, 187, 187, 510 ]	in-angiotensin system plays a more active role in coarctation than previously believed.The pattern of food and mortality in Belgium. Belgians have been gradually shifting from a low ratio of polyunsaturated/saturated fat in their food to a higher one with lower total fat and cholesterol. This has occurred predominantly in the north, where the most obvious change is a decrease in butter consumption and an increase in margarine consumption. The northerners have a four to five times smaller intake of butter than the southerners and nearly double the intake of margarine. Evidence gathered over the past ten years reveals in the north a decreasing serum-cholesterol and in the south a significantly higher serum-cholesterol, associated with higher coronary morbidity and mortality. Life expectancy of males in the north is 2-4 years higher at birth and 2-2 years higher at the age of 30. It is concluded that the food habits of a population can be changed, with great benefit.As ordered reported by the Senate Committee on Veterans’ Affairs on September 12, 2012 S. 2241 would provide additional education benefits to the spouses of servicemembers who died while serving on active duty. The bill also would ensure that veterans, servicemembers, and their dependents receive specific information about educational institutions and other education-related information when using their education benefits and make changes to how the Department of Veterans Affairs (VA) and the Department of Defense (DoD) administer their education benefit programs. As posted on the Web site of the U.S. House of Representatives on December 29, 2012 A bill to provide a one-year extension of the Food, Conservation, and Energy Act of 2008 and amendments made by that Act, with certain modifications and exceptions, to provide supplemental agricultural disaster assistance, to establish dairy producer margin protection and dairy market stabilization programs, and for other purposes.Taking Eden - Issue 10 A physical copy of Issue 10 will be mailed to you. SHIPPING NOTE: I use flat rate shipping through USPS. It is expensive for 1 or two issues, but please note that it does not go up, if you buy more books. A single book would still cost $4 to ship, but would go up with more items. The flat rate shipping is the best deal that I could find for you. Taking Eden - Issue 10 Taking Eden - Issue 10 4.99 A physical copy of Issue 10 will be mailed to you. SHIPPING NOTE: I use flat rate shipping through USPS. It is expensive for 1 or two issues, but please note that it does not go up, if you buy more books. A single book would still cost $4 to ship, but would go up with more items. The flat rate shipping is the best deal that I could find for you. Quantity: Add To Cart Marnie is a naive small town girl lost in the big city club scene. She worked two summers at the local Frosty Cream to save enough money to move to the big city. Staying with her cousin Jasmine, a gothic DJ, she becomes an unwitting part of a unique drug culture. Sky, the owner of multiple night clubs, along with his minions, David and Crystal, are abducting young women. They are using magic to extract their innocence which they process into a designer drug called ‘Eden’. They will stop at nothing to keep a steady stream of product moving to their high profile clientele. When Marnie crosses paths with Sky, will she be able to resist his charm and the excitement of a lifestyle she never imagined?The Commonwealth's low-interest loans proposal for debt-stricken farmers is poorly thought out and unfair, a Budget Estimates hearing has been told. The Federal Government has allocated $60 million over two years for each of the states and the Northern Territory, if they sign up to the Commonwealth's Farm Finance package. But NSW Nationals Senator Fiona Nash has used Budget Estimates to attack the Government's decision to allocate equal funds for each state. "How am I going to feel in NSW, where there are around 43,000 farming businesses, compared with the Northern Territory that's got 522, when there's $30 million on offer for each (over two years)? How am I going to feel in NSW if I desperately wanted to access this and really needed to, and I've hit the cap?" Senator Nash said. "What's that [equate to]? Forty-six farmers out of NSW, 0.1 per cent, compared to the Northern Territory with 522 farmers? How stupid a decision is that?" In addition to the $420 million concessional loans package, the Farm Finance proposal would include changes to make the Farm Management Deposit scheme more accessible, 17 more Rural Financial Counsellors nation-wide, and a promise of debt mediation reform. Federal Agriculture Minister Joe Ludwig says it's an important program that will alleviate the acute debt stress in rural Australia, and once the states sign up, the details of the package will be able to be finalised. How Etsy Grew their Number of Female Engineers by Almost 500% in One Year - bberson http://firstround.com/article/How-Etsy-Grew-their-Number-of-Female-Engineers-by-500-in-One-Year ====== pkteison I'm disappointed that "Key Reality" #2 and #4 in an article about addressing a gender related issue are both unsupported gender stereotypes. Those points could just as easily say 'people' instead of 'women', and as near as I can tell be just as true. I'm quite willing to believe that "People" tend to be conservative about switching jobs, especially if they've had a negative experience in the past. And I can see tech interviews set up "people" for failure; but I don't see anything specific to women in that, unless you want to start from some really negative stereotypes. Working on those issues will probably help your offer acceptance rate, regardless of gender - but you need to be sure you can still distinguish good candidates from bad candidates, so you can't just toss them entirely. So that leads us to the contrast between point #3, don't lower hiring standards, and the conclusion - a method of trying to get better results from reduced experience requirements when hiring. Getting good results from less experience is definitely something important and useful, but less experience -is- a lower standard, so I think the most interesting topic is there. Is watching people in hacker school really enough of an equalizer compared to years of experience? How does it compare to running an intern or co-op program? Is there any problem with the sponsored hackers getting trained on Etsy's dime but working for a competitor? How is hacker school different/better than working with a local university? ~~~ schoper "Unsupported gender stereotypes." Stated also as "opinions based on experience." Possibly also "opinions based on experience that contradict one's equality indoctrination in kindergarten and therefore deserve loud public indignation." ~~~ fleitz The fundamental problem with most stereotypes is that there is generally much more information available by asking the individual. eg. Instead of assuming women are more conservative, just ask the _candidate_ , ask questions surrounding their risk profile. There are great tools one can use from the finance industry to assess an individuals risk profile and tailor an employment package that meets their profile. Some candidates like myself (a guy) want more time off because we'd rather spend time with family than coding. If you can create a tailored work environment you'll have no problem attracting talent that's diverse, instead of just a bunch of people who like to work 80 hours a week. If you offer one size fits all employment you will hire people only for who that size fits. If you offer bespoke employment you'll hire bespoke individuals. ~~~ schoper In a world of perfect information, that would work. In a Bayesian world (ours), it doesn't work. Say that you have two types of widgets, widget A and widget B. Both have tolerances that fall along the same normal distribution but with different means. The mean for widget A is off by 0.1mm, and the mean for widget B is off by 0.2 mm. Now, say that you measure each widget before accepting it, using a perfect measuring function. In this case, it doesn't matter whether you use widget A or widget B. However, in the real world, you have an imperfect measuring function. Say that it gives you an answer along a normal distribution with some standard deviation. Does this make the case for widget A or widget B different? Yes, you'll have more widgets fall within tolerances if you only use widget A. To further improve the model, you would want to know the rejection cost of using an incorrectly sized widget and the supply-demand costs involved in only using widgets of type A. The results of the optimization problem would tell you how much of widget A versus widget B to use. ------ hjay Yes, diversity is important. However, if you are too focused on hiring female engineers, you can bring the overall quality of the team down. Now I do not mean female engineers are any less competent compared to male engineers, but I will give an example from personal experience. The
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326, 703, 30040, 715, 617, 11959, 11320, 15, 1500, 5055, 598, 617, 2343, 43860, 13, 581, 275, 1016, 1133, 15, 187, 187, 3351, 26639, 309, 3078 ]	mainlanders lacked values. That owner, my mother said, stirred rat meat into the ground pork; when you unwrapped the butcher paper, you might catch a faint scent of urine. Pork, in turn, was passed off as beef with a squirt of red dye. So she shopped at a Korean store no bigger than our garage, blocking pinched aisles to ponder the mystery of Korean packaging, while I snuck promising foods into the cart: purple rice, tofu that came in a squeezable tube, a can of what looked like shiny pretzels but turned out to be candied lotus root. At the end of winter, my mother and I made our first visit to the store since Ruby had died. Six weeks had passed. Halley's Comet had been visible as a smudge. It was to return bigger and brighter in 2061, but which of us would be alive to see it? Our aliveness was precarious. Divers had found the crew compartment of the _Challenger_ with all of the bodies inside. Soon the wreckage would reveal that four emergency air packs had been activated; not all of them had died instantaneously. At the grocery store my mother stood in an aisle and stared at the bottled vinegar. She walked the length of the display, following the spectrum from clear to black, and then stood staring at the blackest vinegar. We left the store without buying a thing. She pulled off the road and parked. In a series of actions that startled me, she hopped a guardrail, scampered across the forbidden railroad tracks, and led me down to a huge rock at the beginning of the mudflats. The rock was shaped like a fist, knuckles down. Standing on the rock, towering over the low beach, she said she was trying to listen to it speak, the water, but she couldn't hear it from there. The tide was low; the mudflats were vast. Across the rippled terrain was the same ocean she'd grown up beside; here was Turnagain Arm, which was part of Cook Inlet, which was part of the Pacific Ocean. If you cut a slanted path through the water, she said, you could end up on the eastern shores of Taiwan. Her village, even. You could stagger to land as the first light broke, coming in with the fishermen who'd just climbed down from their anchored boats. They dragged swollen nets of fish behind them on Styrofoam flats. As they came to shore in their rubber waders and boots, long squeaks marked the rhythm of their walking. On the sand, in early light, my mother waited for her father with a bamboo pole. They'd string the net over the pole and carry the fish between them. The short beach was sloped upward, so she walked at the front, and the load was easier on her. My mother climbed off the rock and tested the hardness of the silt. These days, the sun was setting during dinner; we watched each other chewing and gulping in coppery light. In a couple of months the sun would be glowing in electric perimeters around our blinds into evening. Giving us all a charge. The previous summer, Ruby had insisted she was a fish, and my mother had fed her huge sheets of dried seaweed, folding and crumpling them into her mouth. Pei-Pei had asked to go camping with her friends. Camping! my mother exclaimed. Here, where black bears lumbered down from the Chugach Mountains, gorged on salmon at Campbell Creek, and then stuck around to swipe at your garbage cans. Beyond a scrawny, twisted tree was a huge white boulder at the edge of the water. A person was squatting beside it. "My heavens," my mother said, and started running. I tried to grab the bottom edge of her coat, but caught nothing, which made my hands feel empty. We ran past the tumbling of rocks and stray driftwood and made our way toward the boulder. For a while we followed the arcing tracks of a bird, stamped into the silt, a trail of half asterisks. It was a whale, and my first impression of it was its whiteness, unsullied. It was nearly as long as my father's pickup truck, lying in a puddle. The slump of its body came up to the chest of the squatting man, who stood up. "It's still alive," he called to us. "Bleached," I thought he said, but of course he must have said, "Beached." "What is it?" my mother asked, though she knew about the belugas in Cook Inlet. On certain stretches of Seward Highway she told us to watch the water for their writhing bodies, whiter than the crests of the waves. Just once I'd seen a short, misty spray. But she didn't know how to make conversation in English. She was always asking, What time is it?—with her watch curled in her coat pocket. "Beluga," he nearly sang, and each strange syllable was liquid and warm. The man was short, with a wide, deep chest and arms so muscular they hung away from his sides. He was wearing a neon-orange cap with earflaps, from which a few gray curls escaped. I'd never seen such a funny hat, or such a happy color. My mother approached the whale and stopped two yards from its face. I hurried to her. The whale was situated in a crevice of mud and was wriggling its head side to side. I froze in the steady gaze of its small, oily black eye, not so much bigger than a human eye, embedded in a thick ring of skin. The protruding forehead and long mouth gave it a strange expression—a pained smile—as though we'd asked, Shouldn't you be in the water? "Go back," the man said. "It's dangerous, this glacial silt." "Is okay," my mother said, and tapped the toe of her loafer against the ground. When nothing happened, she dug her toe in harder. The whale lifted its head and slapped it back down. There was a cool, silty splatter on my arm. "Oh," my mother said, delighted. Her sweatpants were streaked. Its flippers pressed against the silt and its flukes fanned the air twice. The heft of its midsection was too great for it to do more than flex. Here is a whale, I told myself, and then I wondered if it would die. It looked too big to die, too big to vanish during a sudden, silent creak of the world. And what, I thought, had they done with Ruby's body? The man scratched his bristly neck and flicked the brim of his cap up. "Best she can do is stay still and wait for the tide to come back in." My mother sprang forward, and with a shock I saw her put her hands on the body of the whale. She ducked her head and shoved, arms locked straight, her loafers gouging tracks into the packed silt. Her feet slid out of her shoes. Her socks darkened where they soaked up water. The man belted out a laugh. "That's, like, two tons you're trying to roll." My mother's face hovered beside the blowhole, from which a milky foam was leaking. She slipped her shoes back on and walked around to stand before the whale's face. She touched its forehead bump, the same gesture as when she pressed a palm to our sternums to put us to sleep at night. Pei-Pei, me, Natty. "Sleep," she would say. And, so quietly we could barely hear, "Wake up again tomorrow." The heavy weight of her hand, like sleep itself bearing down on us, paralyzing us where we lay. "Come here," she said to me now. She lifted my hand to the whale's forehead. It was not especially cold or warm. The skin had a rough, porous texture, and behind the skin its flesh was soft, like a ripe peach; I could have left dents with my fingers. I don't know what kind of expression I made, but the man, a yard away, started laughing again. "This kid," he said. I liked the way he laughed, upward, without self-consciousness. He swept an arm back the way we had come. "Nothing to be done. We should get out of here." My mother did not move. She was staring hard at the whale, which began exerting more effort, its head and extremities whapping against the ground. "Do you understand what I'm saying?" His voice sounded far behind me, and when I felt his hand on my shoulder, I started and flung it off. "Easy. Does your ma speak English?" The wind lifted my mother's permed hair into a mane, making her taller and more savage. "Do you? English? Hey, kid. English?" I looked up. A neat mustache hid half his mouth, and his eyes were translucent. "What's your name?" he asked. "Gavin," I said. "How would you spell that in English?" My mother kicked off her shoes. She peeled off her wet socks, rolling them into a single ball that she stuffed into her coat pocket. She picked up her loafers, one in each hand. Immediately I wanted
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281, 452, 247, 2444, 1650, 891, 812, 564, 407, 32, 390, 1127, 479, 281, 187, 2811, 309, 1537, 1089, 581, 32 ]	angry, orange baby that delights spectators as it travels around the world will fly again — right here in Florida. “We plan to win with love, and we LOVE Baby Trump,” said Ida Eskamani, organizer of Win With Love, in a recent statement. “The Baby Trump balloon has become an internationally recognized symbol of President Trump’s regular temper tantrums that endanger this country and our desperate need for an adult in the White House. It is also a symbol of resilience; in the midst of darkness, we can find joy in a giant, inflatable baby. We’re ready to bring Baby Trump to Orlando.” The event which takes place strategically on the evening before Juneteenth, a celebration of the end of slavery, also falls between the 3-year anniversary of the Pulse massacre, and just before the 50th anniversary of the New York City Stonewall Riots. Organizers are currently accepting donations to make the event more accessible and provide interpretation services. The balloon, which originated in the U.K. in 2018 when it flew over Parliament Square in London during an official visit by the president, has been spotted internationally in Ireland, Argentina and France, as well as at various locations in the U.S. according to Wikipedia. This will be the balloon’s first time taking to the warm summer air in Orlando, but it has been viewed in Florida before, near the location of Trump’s Mar-a-Lago resort. For more information about the Win With Love Rally visit the Facebook event page.The Flash: Matt Letscher returning as Reverse-Flash The Flash type TV Show network The CW genre Superhero Where to watch Close Streaming Options From now until our winter TV preview hits newsstands Jan. 15, EW is bringing you 25 scoops in 25 days. Follow the hashtag #25Scoops25Days on Twitter and Instagram to keep up with the latest, and check EW.com/25Scoops25Days for all the news and surprises. As if Barry Allen didn’t have enough on his plate with villain Zoom wrecking havoc on Central City, now he’ll have another speedster to contend with in the new year: Reverse-Flash! No, we’re not talking about Tom Cavanagh yellow-suiting it up once again. EW has learned exclusively that Matt Letscher will be returning to The Flash as Barry’s nemesis, Eobard Thawne, otherwise known as the Reverse-Flash. WANT MORE EW? Subscribe now to keep up with the latest in movies, television, and music. A brief refresher from last season: Letscher’s Eobard Thawne traveled back in time and killed Barry’s (Grant Gustin) mother before getting trapped in that era. Eobard then absorbed Harrison Wells’ (Cavanagh) DNA to take on his persona, and trained Barry to be fast enough to tap into the Speed Force so he could return home. But his ancestor Eddie Thawne (Rick Cosnett) killed himself, effectively erasing Eobard from the timeline. So, considering the original Reverse-Flash met his maker last season, we may be looking at a speedster from a different Earth. Here’s what executive producer Todd Helbing, who penned the episode featuring Letscher’s return with Aaron Helbing, would reveal: “His impossible return to Central City puts a member of the S.T.A.R. Labs team in unexpected danger, forcing Barry to make a life-changing decision.” Letscher (Scandal, The Carrie Diaries) is slated to appear in episode 211, which is fittingly titled “The Reverse-Flash Returns.” The Flash returns Tuesday, Jan. 19 at 8 p.m. ET on The CW.misterhouse-users I just recently started using MH, everything works good that I have configured so far. The question I have is, I use x10 devices to control some stuff around the house, mainly just lights for now(using LM15A) . I use the CM17(and RR501 Remote module) & CM11 to control the various items. The problem I have is this, in the kids room is a HR12A Powerhouse controler that the kids can use to control lights until i get some more feature such as audrys added, but is there a way to check , lets say every 10 minutes to find out what the current status of the x10 devices are? and adjust MH so it know if the kids turned a light on or off using the remote. Thnx Dick Bradford -- No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.1.405 / Virus Database: 268.12.8/455 - Release Date: 9/22/2006 I am currently using CM11 & CM17 to control my X10 devices, but I am having the hardest time with them, So far this year I have killed 2 CM17's ... Not quite sure why, but is there any type of interfaces that are compatible with MH that can control X10 devices and have a better life span? other than the CM11 ? Thnx Dickie -- No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.1.409 / Virus Database: 268.13.31/522 - Release Date: 11/7/2006 Dickie- I recently picked up an ACT x10 interface on sale from smarthomeusa, but haven't had time to set it up and test it out. I guess I've been really lucky because my cm11 has been working fine for a number of years. I got this primarily as a backup unit, but plan on testing it out soon. I'll report back as soon as I have some info. Joel On Tue, 7 Nov 2006, it would appear that Dickie Bradford wrote: > I am currently using CM11 & CM17 to control my X10 devices, but I am having > the hardest time with them, So far this year I have killed 2 CM17's ... Not > quite sure why, but is there any type of interfaces that are compatible with > MH that can control X10 devices and have a better life span? other than the > CM11 ? > > Thnx > > Dickie The LM15a is not a 2 way device, so you cannot directly find out if the light has been turned on/off. HOWEVER, if they are using the remote to turn them on / off, then you can simply assign the devices to MH via the CM11 and it will automatically synchronize its state every time a button is pushed (as long as MH is running when the button is pushed). Hope that helps, -J On Sun, 24 Sep 2006, Dickie Bradford wrote: > I just recently started using MH, everything works good that I have > configured so far. > > The question I have is, I use x10 devices to control some stuff around the > house, mainly just lights for now(using LM15A) . I use the CM17(and RR501 > Remote module) & CM11 to control the various items. The problem I have is > this, in the kids room is a HR12A Powerhouse controler that the kids can > use to control lights until i get some more feature such as audrys added, > but is there a way to check , lets say every 10 minutes to find out what the > current status of the x10 devices are? and adjust MH so it know if the kids > turned a light on or off using the remote. > > Thnx > > Dick Bradford > > > > > -- > No virus found in this outgoing message. > Checked by AVG Free Edition. > Version: 7.1.405 / Virus Database: 268.12.8/455 - Release Date: 9/22/2006 > > > ------------------------------------------------------------------------- > Take Surveys. Earn Cash. Influence the Future of IT > Join SourceForge.net's Techsay panel and you'll get the chance to share your > opinions on IT & business topics through brief surveys -- and earn cash > http://www.techsay.com/default.php?page=join.php&p=sourceforge&CID=DEVDEV > ________________________________________________________ > To unsubscribe from this list, go to: http://sourceforge.net/mail/?group_id=1365 > > > I am trying to update the Light objects with UPB so that when instantiated they synchronize with the item they are representing. I was wondering what is used to request an update from the X10/Insteon device, so I can make that universal. So far in UPB lingo, this is requested currently with: $upb_light->set("report"); which triggers the device to send back its current state and the underlying object receives this and sets it state accordingly. I know the X10SW and Insteon must have something similar and was wondering what that is (I dont recall how the X10SW did that) -J Thnx for the info J would you happen to have a working example i could go by? or point me to where I might find one?
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470, 285, 608, 575, 3272, 36, 2796, 53, 11, 5062, 4793, 95, 470, 575, 3272, 36, 481, 380, 2544, 954, 4518, 2529, 1840, 403, 2540, 275, 253, 11053, 285, 6420, 18288, 4811, 273, 16795, 13, 534, 403, 2783, 281, 320, 34562, 4811, 15, 187, 187, 30724, 20553, 15524, 598, 281, 1384, 2270, 1918, 247, 2590, 2460, 273, 271, 2572, 275, 8609, 5300, 275, 16795, 1563, 2544, 275, 253, 2978, 273, 253, 34724, 14, 4924, 285, 5675, 12396, 15, 9937, 253, 12739, 273, 253, 6706, 2324, 13774, 7952, 1566, 13, 841, 8609, 2544, 3176, 281, 320, 13857, 323, 21047, 313, 3594, 317, 44109, 285, 611, 1504, 91, 999, 25928, 1008, 1311, 1047, 2498, 21525, 715, 2395, 253, 1543, 273, 4188, 1975, 2175, 24025, 326, 271, 2572, 275, 2329, 3276, 407, 337, 575, 3272, 36, 591, 807, 17308, 684, 253, 3116, 273, 6244, 407, 374, 281, 608, 575, 11015, 13, 285, 407, 247, 13365, 390, 594, 1897, 13, 672, 253, 2572, 275, 8609, 5300, 7350, 253, 7203, 2180, 313, 74, 15, 66, 15, 775, 78, 38853, 88, 9327, 285, 416, 32617, 8260, 1008, 1311, 25, 2194, 9730, 21608, 1162, 355, 15, 1008, 1311, 1099, 2194, 500, 255, 14617, 518, 285, 8178, 1403, 3109, 1008, 1311, 1093, 6660, 581, 778, 5467, 326, 253, 2440, 273, 288, 430, 2702, 459, 275, 16795, 310, 1896, 342, 1675, 281, 253, 10199, 273, 747, 5461, 28992, 19112, 390, 1014, 747, 3417, 15, 1723, 13, 352, 556, 281, 320, 8042, 562, 326, 841, 403, 4101, 35684, 2515, 326, 4446, 17177, 11026, 285, 3290, 15, 16795, 434, 39222, 7952, 8232, 387, 4766, 4329, 11434, 9365, 1534, 734, 1136, 780, 13099, 273, 26611, 8322, 285, 1824, 23835, 13, 3340, 275, 253, 5768, 347, 247, 906, 313, 2290, 79, 4530, 1162, 355, 15, 1008, 1311, 1671, 2498, 5595, 273, 16795, 3386, 4016, 12015, 1420, 1824, 6654, 5768, 2193, 313, 56, 3170, 3155, 285, 530, 1344, 79, 335, 1008, 1311, 2945, 6660, 534, 1543, 275, 247, 6379, 275, 1824, 5718, 285, 5768, 1824, 46163, 313, 46840, 7184, 1162, 355, 15, 1008, 1311, 1610, 2498, 1294, 6499, 612, 522, 30379, 43011, 7133, 13, 8877, 8558, 407, 3081, 3276, 3116, 13, 588, 1421, 281, 271, 9592, 21198, 1824, 7563, 13, 285, 2779, 625, 12848, 390, 1014, 3710, 9313, 14, 22210, 17177, 11026, 313, 46840, 7184, 1162, 355, 15, 1008, 1311, 1610, 1092, 1535, 79, 4530, 1162, 355, 15, 1008, 1311, 1671, 2498, 187, 187, 4041, 1364, 671, 4456, 326, 8588, 2515, 13, 275, 1798, 253, 5927, 2329, 3276, 347, 973, 347, 9559, 16958, 13, 403, 8127, 7976, 327, 1980, 2515, 313, 70, 15, 72, 904, 34724, 19781, 84, 10, 313, 54, 1344, 79, 335, 1162, 355, 15, 1008, 1311, 1787, 2498, 19926, 5829, 1079, 1783, 323, 16795, 285, 697, 2067, 5799, 4811, 13, 534, 403, 4942, 6447, 275, 8609, 2426, 13, 2167, 12848, 39331, 13, 1057, 417, 2085, 247, 2590, 3662, 342, 1675, 281, 13554, 387, 253, 1980, 1268, 15, 187, 187, 1552, 789, 369, 4516, 407, 253, 2199, 27, 24819, 2196, 271, 41275, 25780, 323, 28678, 15836, 29930, 2903, 405, 942, 323, 5625, 15111, 13869, 342, 8057, 14, 18919, 11401, 942, 13, 3313, 6875, 6807, 330, 17659, 11240, 1621, 15, 470, 28766, 25139, 15, 187, 60, 34, 2554, 273, 24109, 14, 882, 267, 322, 16370, 323, 253, 8137, 273, 22815, 431, 7736, 2770, 1570, 187, 34, 5976, 14, 2913, 14, 744, 637, 574, 2570, 7898, 29931, 285, 6561, 14923, 21935, 13, 1293, 13406, 19147, 275, 734, 882, 267, 29253, 285, 1481, 14478, 15, 9064, 14, 6967, 322, 4708, 313, 20, 37, 322, 4708, 10, 1783, 273, 24109, 14, 882, 267, 322, 16370, 941, 5189, 4373, 468, 12213, 275, 253, 987, 11935, 27317, 13, 253, 15919, 13787, 285, 253, 26382, 13, 534, 2692, 3500, 2211, 12213, 1309, 734, 882, 267, 2180, 15, 2053, 4342, 5125, 326, 253, 22815, 431, 7736, 2770, 13164, 275, 253, 987, 11935, 27317, 15, 844, 7945, 326, 495, 37, 322, 4708, 1783, 273, 24109, 14, 882, 267, 322, 16370, 651, 320, 9371, 281, 4271, 253, 22815, 431, 7736, 2770, 15, 50, 27, 187, 187, 11340, 310, 417, 2444, 327, 253, 9763, 534, 369, 3559, 771, 595, 187, 187, 12092, 309, 452, 247, 6409, 327, 3973, 20775, 285, 309, 22944, 247, 8753, 489, 432, 806, 20775, 281, 1273, 20775, 347, 8753, 489, 4559, 595, 15, 3954, 327, 253, 1273, 20775, 309, 717, 11365, 247, 26645, 8246, 33866, 285, 281, 564, 327, 253, 2626, 9763, 309, 717, 13383, 253, 9763, 9, 339, 25070, 36978, 10, 1292, 697, 417, 2444, 15, 2626, 19879, 2506, 626, 3249, 598, 15, 13529, 9369, 672, 309, 5532, 253, 2840, 6409, 15, 209, 187, 4943, 310, 253, 1273, 20775, 2127, 187, 11632, 1735, 8880, 7146, 264, 9, 36294, 27, 9571, 8880, 2, 910, 187, 50274, 1059, 1379, 13443, 16227, 8929, 426, 1881, 15, 19192, 4697, 47346, 43760, 4513, 20775, 3378, 18483, 1587, 21528, 13443, 16227, 8929, 2807, 347, 2, 11668, 13443, 16227, 8929, 187, 50266, 21528, 13443, 16227, 8929, 15, 39816, 426, 7408, 187, 50266, 1286, 15, 37336, 8929, 29006, 11340, 20775, 9, 21528, 13443, 16227, 8929, 13, 21530, 27, 2032, 10, 187, 94, 187, 187, 8497, 27, 309, 1053, 626, 878, 253, 42619, 7912, 327, 6347, 9182, 31555, 594, 1223, 15250, 352, 771, 595, 352, 1904, 626, 921, 253, 15034, 7912, 15, 1292, 309, 878, 253, 15034, 7912, 327, 253, 2626, 581, 15, 50276, 2598, 28763, 2139, 309, 717, 13383, 275, 6563, 74, 356, 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5672, 13, 12240, 27, 18789, 10, 187, 187, 19, 10, 4325, 1273, 20775, 368, 476, 7450, 12245, 20775, 275, 187, 50275, 1286, 15, 8002, 74, 356, 19606, 8929, 15, 187, 10639, 2708, 2127, 275, 6347, 20775, 327, 26645, 12121, 187, 1059, 2626, 20775, 426, 12693, 29569, 4697, 9, 1590, 27, 346, 13030, 995, 13204, 27, 5296, 481, 43760, 4513, 20775, 3378, 18483, 1587, 68, 18483, 2807, 347, 2, 12245, 20775, 1881, 15, 37336, 8929, 29006, 11340, 20775, 9, 19016, 20775, 1157, 21530, 27, 2032, 3117, 535, 2948, 13283, 4658, 187, 4064, 5135, 15, 6443, 15, 17494, 1395, 23310, 6435, 947, 535, 187, 2437, 22272, 14201, 16468, 9, 6082, 2262, 535, 50274, 16680, 426, 12166, 187, 50274, 7083, 16970, 426, 16708, 535, 50274, 1545, 4772, 4478, 21920, 1286, 13, 13283, 13, 3159, 3550, 30, 5758, 1587, 4658, 16, 1156, 64, 11242, 16, 3418, 3550, 15, 10134, 6788, 1088, 8737, 5715, 1511, 30, 11336, 2262, 187, 50270, 1286, 15, 13362, 426, 13283, 187, 50270, 1286, 15, 12113, 426, 3159, 3550, 187, 50270, 1286, 15, 881, 426, 1511, 535, 50274, 1545, 1611, 64, 455, 64, 267, 46042, 9, 1286, 2262, 187, 50270, 32488, 15358, 1046, 5933, 2130, 327, 253, 4382, 970, 253, 686, 267, 46042, 64, 15735, 8, 3470, 432, 13283, 4658, 187, 50270, 266, 1650, 273, 436, 3470, 651, 320, 27, 187, 50270, 17636, 3379, 9, 13362, 4658, 15, 267, 46042, 64, 15735, 10, 187, 50270, 1178, 40116 ]	dates) at selected stations representing fruit-growing regions in Poland (1951--2010) In the central-north region of Poland, the upward trend associated with local heat resources is accompanied by a small, but statistically significant, change in the occurrence of spring frost. For example, in Skierniewice, frost can be expected less than 2 days in advance (Fig. [6](#Fig6){ref-type="fig"}), with a trend of GDD totals of 42.1/10 years. The lowest T ~min~ values during the plant growth period (GDD ≥ 150) may reach −3.0 °C. The central-southern and western regions of Poland are characterized by frost periods ending increasingly early (in both cases---Sandomierz and Opole stations---\>2 days/10 years), with a significant increase in thermal resources (respectively: 29.5 and 51.9 GDD/10 years) (Fig. [6](#Fig6){ref-type="fig"}). The lowest minimum temperature during the growing season, after exceeding the threshold of GDD = 150, was −1.9 °C in Sandomierz, while in Opole, it was −2.8 °C. The lowest minimum temperature value for the remaining thresholds was −0.8 °C. Conclusions {#Sec8} =========== Global studies on climate change impacts on agriculture, horticulture, and forestry confirm unanimously that an increase in the length of the growing season followed by a higher amount of thermal resources may enhance crop production at mid- and high latitudes, and increase potential output at harvest time as well as improve forest productivity (Winkler et al. [@CR40], Linderholm et al. [@CR21], Trnka et al. [@CR35]). However, the rate of the observed changes may have a large impact on already living species' distribution and the spread of insects, as well as may affect grain yields and crop seed production (Winkler et al. [@CR40], Thuiller et al. [@CR34]). Moreover, the increase in heat accumulation at the time of the last spring frost event as well as the variability of the frequency of frost events after sensitive plant growth stages is reached either maintains or increases frost risk (Winkler et al. [@CR40], Trnka et al. [@CR35]). Although the research conducted so far for the territory of Poland has confirmed, as already stated, both global and regional tendencies, it was carried out only for selected stations with limited representativeness. Therefore, the results cannot be fully applied to the whole area of Poland. The use of a gridded database in the current analysis assures continuous information on temperature differentiation and provides a fairly clear picture of GDD value variability in Poland. Furthermore, it combines a thorough characterization of thermal resources across the country with frost risk analysis for several different spring phenophases expressed by GDD accumulation, with a special focus on the main fruit-growing regions of the country. A statistically significant increase in average annual air temperature (about 0.2 °C/10 years), manifesting itself in a temperature rise in the spring months (about 0.4 °C/10 years) and in an extension of the growing season by an average of 2.5 days/10 years, has been observed. The trends described in the study result in an increase in heat resources with the greatest intensity between 0 and 5 °C (T ~base~ 0 °C). The changes most clearly described above are observed in the southern and southwestern regions of Poland, which are considered to be warmer regions. Future projections simulated up to 2090 give a clear image of an increase in thermal resources in Poland following changes in the length of the frost-free and growing seasons. Despite the implications of the aforesaid climate model, these thermal changes appear to be favorable for agriculture (Graczyk and Kundzewicz [@CR14]). Taking into account the results of phenological studies confirming that an increase in air temperature by 1 °C per year accelerates the growth of plants by 2 to 5 days, and by a dozen or so days, when the increase in thermal resources concerns the spring period (i.a. Chmielewski and Rötzer [@CR8]; Menzel et al. [@CR25]; Jatczak and Walawender [@CR18]), one may assume that the development of horticulture in Poland is possible with respect to the introduction of new thermophilic varieties or even new species. However, it has to be pointed out that these are hydrothermal conditions that drive crop yields and quality. Poland's continental climate zone at middle latitudes faces significant interannual variability of precipitation amounts and water deficits, especially in the summer as a result (Trnka et al. [@CR35]). Most of Poland features negative climatic water balance summer values (Wypych and Ustrnul [@CR42]), which results in a decrease in water storage and summer water shortages (Szwed et al. [@CR33]). Projected evapotranspiration intensity, driven primarily by additional temperature growth, will lead to an increasingly stressed water budget, and likely more varied or even limited rain-fed crop yields (Szwed et al. [@CR33], Trnka et al. [@CR35]). One must also remember that weather conditions, in particular the minimum air temperature as well as extreme phenomena, are largely dependent on local conditions (e.g., frost hollows) (Ustrnul et al. [@CR37]). Mesoscale analysis for Poland and its several distinct regions, which are relatively uniform in thermal terms, though varied environmentally, does not provide a clear answer with respect to trends at the local level. This work was supported by the project: Towards an Integrated Framework for Climate Change Impact Assessments for International Market Systems with Long-Term Investments, National Science Foundation CNH Award No. 0909378. [A role of peri-ictal SPECT for the identification of epileptogenic focus]. A 42-year-old man had complex partial epilepsy and secondary generalized seizure, without remarkable abnormalities in interictal EEG and head MRI. Three-dimensional SRT (3D SRT) analysis of peri-ictal SPECT data detected hyperperfusion in the right temporal lobe, the basal nucleus and the hippocampus, which showed hypoperfusion during interictal period. These findings suggested that the epileptogenic focus existed in the right temporal lobe. We concluded that 3D SRT analysis of peri-ictal SPECT would be helpful to identify the epileptogenic focus.Q: push is not working on the controller which was presented modally Hello I have a button on FirstViewController and I dragged a segue from firstViewController to secondViewController as segue Modally. Now on the secondViewController I am generating a Button Programmatically and to go on the third controller I am pushing the controller(segue Push) But its not working. thirdcontroller doesn't comes up. Nothing happening when I click the custom button. Here is the secondViewController code func nextButtonClicked(sender:UIButton!){ let takeProductPhotoController = self.storyboard!.instantiateViewControllerWithIdentifier("takeProductPhotoController") as! TakeProductPhotoController takeProductPhotoController.trip = trip self.navigationController?.pushViewController(takeProductPhotoController, animated: true) } Note: I don't need the NavigationBar on Second View Controller so while presenting it modally it didn't show the navigationBar. But I need the navigationBar on the third one. So thats why I am pushing in naviagtioncontroller A: Whenever you want push from the popped controller you have to creat the new NavigationController & also set the ViewController which you want to present modaly as rootViewController of navigationController. When we want to present the SecondViewcontrollermodally, We are presenting navigation controller with rootViewController set to SecondViewController. So we have created the new navigation stack. After that we are going to push the controller in the new navigation stack created while presenting SecondViewController. 1) Your code should be look like this in FirstViewController let secondViewController = UIStoryboard(name: "Main", bundle: nil).instantiateViewControllerWithIdentifier("aIdentifier") as! SecondViewController let nav = UINavigationController(rootViewController: SecondViewController ) self.presentViewController(nav, animated:true, completion:nil) 2) From secondViewController you can push ThirdViewController in self.naviagtionController. Write below code in SecondViewController on Button Action let thirdViewController = UIStoryboard(name: "Main", bundle: nil).instantiateViewControllerWithIdentifier("cIdentifier") as! ThirdViewController self.navigationController?.pushViewController(thirdViewController , animated: true)} import hashlib from lib.core.settings import LOGGER class HashCracker(object): results = {} cracked = False def __init__(self, hash, wordlist=open("lib/text_files/wordlist.txt").readlines(), type=None): self.hash = hash self.words = wordlist self.type = type def try_all_algorithms(self): """ Try every algorithm available on the computer using the 'algorithms_available' functions from hashlib an example of this functions would be: >>> print(hashlib.algorithms_available) set(['
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32924, 1211, 6109, 33310, 187, 395, 10469, 481, 45946, 8653, 16557, 313, 9328, 6138, 347, 45859, 275, 36605, 13, 285, 187, 4297, 405, 7019, 3692, 16557, 588, 320, 4136, 949, 481, 187, 187, 42, 476, 49860, 512, 1388, 15, 187, 187 ]	refrigerant is deposited on the exterior surfaces of some of the heat transfer tubes in the tube bundle and the other heat transfer tubes in the tube bundle are immersed in the liquid refrigerant that has been collected at the bottom portion of the shell. Although the flooded evaporators exhibit high heat transfer performance, the flooded evaporators require a considerable amount of refrigerant because the heat transfer tubes are immersed in a pool of the liquid refrigerant. With the recent development of new and high-cost refrigerant having a much lower global warming potential (such as R1234ze or R1234yf), it is desirable to reduce the refrigerant charge in the evaporator. The main advantage of the falling film evaporators is that the refrigerant charge can be reduced while ensuring good heat transfer performance. Therefore, the falling film evaporators have a significant potential to replace the flooded evaporators in large refrigeration systems. Regardless of the type of evaporator, e.g., flooded, falling film, or hybrid, a distributor is provided to distribute refrigerant entering the evaporator to the tube bundle. U.S patent publication No. 2015/0053378 discloses one example of such a distributor. The distributor is designed to separate vapor refrigerant from liquid refrigerant and distribute liquid refrigerant toward the tube bundle. Particularly in the case of a falling film type evaporator such distribution is desired. Google is Crushing the Internet - dforrestwilson http://theweek.com/articles/693488/google-monopoly--crushing-internet ====== empath75 I don't have a strong opinion about whether or not google should be regulated or not. However, this guy doesn't seem appreciate the scale of the difficulties that google solved and how much better google was than the competition. They almost single-handedly transformed the internet into a useful tool. Altavista and yahoo were like looking up information in a card catalog in comparison. It wasn't just a first mover advantage. And they followed it up by releasing, an ads platform that made everyone else look like amateur hour, a mail product that was far better than hotmail, a mapping tool much better than MapQuest, and a web browser that was far better than ie or Firefox. They are in the position they're in because they solved a lot of difficult problems and made it look easy. If we ever get to the point that we need as a society to rein them in, we should do it with a full understanding of what they've accomplished. It's bizarre to accuse the company that made the internet into what it is today of somehow crushing it. ~~~ wazoox Basically you're explaining that they earned a monopoly for a reason. That's true. And there are always true advantages to monopoly (standardization, economy of scale, prices stability ...). However monopolies harm the economy and the public good in the long run. See, that works for any past monopoly: I don't have a strong opinion about whether or not Microsoft should be regulated or not. [...] It's bizarre to accuse the company that made the PC into what it is today of somehow crushing it. I don't have a strong opinion about whether or not AT&T should be regulated or not. [...] It's bizarre to accuse the company that made the telephone into what it is today of somehow crushing it. I don't have a strong opinion about whether or not Standard Oil should be regulated or not. [...] It's bizarre to accuse the company that made the oil industry into what it is today of somehow crushing it. ~~~ bgw It has always been strange for me to understand Google search as a monopoly. First, there are competitors. Second, it's free (yes, I know you pay with data). Third, you can use the internet without using any of Google's services (except adsense, I suppose). How is Google's search a monopoly when it's the user who is deciding they prefer it to Bing or Duck Duck Go or Yahoo? Perhaps my understanding of monopoly is incomplete because this makes no sense to me. ~~~ pixl97 If I produce content that I want other people to view, I have to cater it to googles requirements or almost nobody sees it. Simply put Google is the biggest driver of traffic and ad dollars. If you play by (or if you game) Googles rules you can make piles of cash, driven by the traffic they send your way. Then the next day it can dry up with no reason given. Saying that the user prefers it is a slightly backward way of thinking about it. Does the user prefer it because it is better, or is it because abuse of their monopoly doesn't allow other providers to achieve the same quality of service? ~~~ scarface74 _If I produce content that I want other people to view, I have to cater it to googles requirements or almost nobody sees it. Simply put Google is the biggest driver of traffic and ad dollars._ I know of a few bloggers who don't seem to be dependent on Google or Facebook to maintain their business. 1\. John Gruber (daringireball.com). He made a name for himself over 15 years and is famous enough to be on the shortlist of people that Apple always reaches out to when they want to do a four or five person press event. He routinely gets VPs from Apple on his podcast. He sells RSS sponsorships - one at the beginning of the week and one at the end of the week. He also makes money from his podcast. He did lose half his readership after Google killed off Google Reader, but he said since he never sold his ads based on the number of readers, it hasn't hurt his business too badly. 2\. Ben Thompson (stratechery.com). He posts once a week to his blog, became popular and has over 2000 subscribers to his newsletter that he charges $100/a year for. He has one advertiser for his podcast - mailchimp - they sponsored him for an entire year. 3\. Marco Arment - first architect of Tumblr, creator of Instapaper, and now Overcast. He is also a decently well known blogger in the Apple ecosystem. He basically created his own podcast app ad sales platform, and has a popular podcast. 4\. Horace Deidu. He started out as a blogger/analyst and now he gives speeches and does workshops worldwide. It's hard getting noticed over the noise, but it can be done. It is possible to create a viable content business without an over reliance on Google. ------ 5_minutes While I understand the sympathy here for Google's accomplishments, and don't agree with many of the OP's points - just objectively, it's scary for us all to be dependent on one commercial company. Wether they earned to be in that position or not. It's also hard to compare things: the scale of the current internet usage, the type of information that is available. (And what can be influenced by showing what). This scale is much, much wider then what happened to AT&T back in the days. That said, since Apple and MS are also getting away with very similar things, I don't see a point in punishing Google. Especially, as them all being US companies. The solution of breaking up Google and then putting weaker foreign company in the front-seat, by doing so -- also would not make any sense. ------ fear91 I'm wondering when, if ever, the general public will start recognizing Google as one of the "big brothers". Somehow it's still perceived as this "cool" startup but they squash small businesses, avoid taxes, are in bed with intelligence agencies, etc. ~~~ quickben I'm old enough to remember the techies backlash over targeted advertising in Gmail. It seemed the google's PR started throwing cash at it for years to "educate" the public. The general public appeared to be a complacent herd of sheep like creatures that would embrace convenience over everything. Maybe in your circles Google is "cool". In my circles it's necessary evil. The platform/network effect is so strong there is no escaping it. The US is invested my money wise too deep and won't do what they had the backbone to do with SO and the rest. So, "when, if ever", won't be anytime soon. Meanwhile, innovation suffers. They killed chat protocols interfaces (pure monopoly abuse since they have most users), the buried end-to-end encryption, they killed bunch of competing businesses by promoting their side businesses on the search page higher, etc. Http2 could have had things for the users in it (if one goes through the troubles of upgrading a network layer). Instead it had "cut off download at instant if requested" and other features that made web crawling (though not necessarily browsing and developing) easy. Going forward, they will be cleaning the advertising agency landsccape to get rid out of competition with : Amp ( since they de facto own mobile browsing and Android). Desktop displayed ads (they announced as blocker in chrome, and guess twice whose ads will be allowed through). I can enumerate all day.
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11, 418, 972, 486, 253, 8990, 27436, 281, 4076, 314, 823, 7066, 911, 47554, 13175, 281, 634, 2199, 1293, 1907, 281, 3630, 253, 39870, 3789, 2127, 323, 2444, 342, 253, 7066, 911, 47554, 33261, 187, 187, 1992, 475, 69, 422, 275, 11, 285, 923, 849, 4384, 911, 442, 8809, 17261, 2789, 634, 1495, 1805, 13, 2451, 562, 253, 187, 27, 709, 30337, 28782, 5478, 65, 2, 187, 187, 510, 11447, 16398, 187, 26446, 187, 187, 537, 281, 291, 658, 1450, 187 ]	Thoroughbred racehorse who was the champion filly of her year and beat the colts in the 1987 New Zealand Derby. After finishing second in her debut, Tidal Light won ten of her next 13 races, including the Derby, Avondale Guineas, Waikato Guineas, Canterbury Guineas and a Group 1 victory in the Air New Zealand Stakes over older horses under weight-for-age conditions, beating the great Solveig. She returned in the spring of 1987 as a four-year-old, but failed to win a race and despite some good performances was obviously not the same horse she had been the previous season. Her three-year-old season earned her both the Three Year-Old of the Year award and Horse of the Year, a rare feat for a filly. She died in March 2007. Category:1983 racehorse births Category:2007 racehorse deaths Category:Racehorses bred in New Zealand Category:Racehorses trained in New Zealand Category:Thoroughbred family 21-aA father-of-two has died days after he was stabbed multiple times in a horrific road rage attack on an Adelaide street. Troy James McLean, 34, tried to drive himself to hospital while bleeding profusely, but crashed into a parked car just metres before he got there. The owner of the car he drove into found him slumped behind the wheel when he went to confront him soon after the stabbing at 10.40am on Saturday. Benjamin Joshua George, 25, allegedly stabbed Troy James McLean to death in a horrific road rage attack on an Adelaide street McLean tried to drive himself to hospital while bleeding profusely, but crashed into a parked car just metres before he got there Mr McLean was rushed to Royal Adelaide Hospital in a serious condition and had emergency surgery while clinging to life, but died on Tuesday. Charges against Benjamin Joshua George who allegedly stabbed him during a roadside argument will be upgraded to murder. The 25-year-old allegedly stabbed him before driving off and leaving Mr McLean badly injured at a busy intersection. George begged the victim's family for forgiveness as he appeared in court on Monday, saying 'can I just say I'm sorry to everyone' Mr McLean's bloodstained car that he tried to drive to the hospital after he was stabbed He begged the victim's family for forgiveness as he appeared in court on Monday, saying 'can I just say I'm sorry to everyone', according to the Adelaide Advertiser. George was remanded in custody to face court again in January, causing his family to burst into tears as they watched from the gallery. Magistrate Yoong Fee Chin said George could apply for bail at a future court date.Field of the Invention The present invention relates to a reproducing apparatus for reproducing information from a recording medium, a program used for reproduction, and a recording medium with the program recorded. Description of the Prior Art To manage contents recorded in a recording medium, in audio-visual equipment such as CD and DVD players, a method is devised to obtain information from a recording medium itself or network and produce content information. (Refer to Japanese Patent Laid-open No. 2001-307464, for example). In recent years there has been a growing use of broadband networks. Besides information in small amounts, there are thus available more and more subtitle information for movie titles and more and more diversified contents such as images and audio.Scotland’s largest independent courier has bucked an industry trend of cutbacks and liquidations and is set to announce the busiest year in its 30 year history – but warns that future fuel price rises could remove any profit from low-margin public-sector contracts. With the courier industry enduring a turbulent 12 months, highlighted by the dramatic Christmas Eve demise of City Link, further industry setbacks have resulted from the cut back of many public sector contracts. Despite this, 2015 has proven to be a particularly busy period for Eagle Couriers which is on track to increase the total number of consignments delivered, breaking the one million mark for the first time in its history, with revenue also up 10 per cent on 2014. Eagle Couriers’ 100-strong fleet of drivers have so far made close to 20,000 deliveries per week, in part due to its role delivering significant public sector contracts. 2015 has also seen the firm commit to a six-figure sum move to new purpose-built headquarters in Bathgate, maintaining its bases in Edinburgh, Glasgow and Aberdeen. The new West Lothian hub was officially opened in October by Hannah Bardell, MP for Livingston and the SNP’s spokesperson for Business Innovation and Skills. Fiona Deas, Co-Director of Eagle Couriers, said: “By working tirelessly to build recognition as a reliable, efficient and adaptable service we have been able to boost turnover despite difficult economic conditions. “We have established a strong team which has provided a foundation to build on past contract successes and take on more large, often high pressure contracts knowing that we can deliver on them. “The difficulty we face now is that many contracts are being operated along very thin margins – an increase in costs such as fuel could suddenly cause huge problems in the industry. This looks set to be the biggest challenge in the coming years. “The better the firm does, the more Scottish jobs we can offer and support – as great as this is, we are in effect banking on fuel prices remaining relatively low.” The past year has seen Eagle Couriers land prestigious contracts, including the transportation and logistics behind the general election voting papers and ballot boxes and a new contract with the leading online retailer. The Bathgate business also continued sensitive and demanding work with national examination boards, organising the delivery and collection of papers from almost every school in mainland Scotland. The other Director at the helm of Eagle Couriers, Jerry Stewart, enjoyed a positive 12 months with his induction as a Fellow of the Institute of Couriers – in a ceremony at the House of Lords earlier in the year – proving to be a particular highlight. Jerry, a 30 year veteran of the sector, said: “It’s been a big year personally and has provided me with further evidence that this industry truly never stands still. “It is now essential that firms in the sector are at the forefront of technology, both in terms of the day-to-day operations and in customer service – where up to the minute parcel tracking is an expectation. “We are delighted to be able to announce such positive figures and it is a real endorsement of the hard work that has gone on behind the scenes making sure we are at the forefront of any advances. “The courier and logistics industry has changed dramatically and it has been tough at times – something that is evident with the collapse and cutbacks seen with some of our notable UK-wide competitors.” Eagle Couriers has a 3500-strong client base including the BBC and the NHS, public sector organisations and sole traders. As business-to-business experts, Eagle Couriers help other firms operate more efficiently and profitably by safely delivering on time everything from documents, medical samples and engine parts to sports footage, scripts and TV props. A total of 83,077 passengers are expected to land at the airport within five days of Christmas, about 36,000 more than at Glasgow which will be the second busiest Scottish airport. edinburghnews.scotsman.com/ne…Order filed February 15, 2018 In The Fourteenth Court of Appeals ____________ NO. 14-17-00434-CV ____________ IN THE INTEREST OF Z.Q.N., A MINOR CHILD On Appeal from the 309th District Court Harris County, Texas Trial Court Cause No. 2016-14463 ORDER The brief of appellant, L.M.B., was due February 7, 2018. No brief or motion for extension of time has been filed. Unless appellant files a brief with this court on or before March 9, 2018, the court will dismiss the appeal for want of prosecution. See Tex. R. App. P. 42.3(b). PER CURIAM .. currentmodule:: webexteamssdk ============= webexteamssdk ============= Simple, lightweight, scalable Python API wrapper for the Webex Teams APIs ------------------------------------------------------------------------------- Welcome to the docs! webexteamssdk is a community developed Pythonic wrapping of the Webex Teams APIs. The package represents all of the Cisco Webex Teams API interactions via native Python tools. Making working with the Cisco Webex Teams APIs in Python a native and natural experience. webexteamssdk helps you get things done faster. We take care of the API semantics, and you can focus on writing your code. With webexteamssdk, you can easily: * Interact with the Webex Teams APIs in an interactive Python session * Quickly create code that enables you get something done in Webex Teams * Leverage the API wrapper to cleanly add Webex Teams functionality to your project without having to write the boilerplate code for working with the Webex Teams APIs To dive in and see how webexteamssdk makes your life better, check out the :ref:`Quickstart`! The User Guide ============== .. toctree::
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5438, 285, 14663, 15, 44372, 14, 251, 3733, 5609, 403, 11217, 715, 436, 11088, 2086, 1108, 38746, 985, 873, 598, 13, 14925, 19274, 285, 9797, 18543, 15, 187, 187, 13425, 29746, 8339, 187, 187, 510, 2105, 323, 436 ]	Could it be a hotspot? Moses had one a few years ago that went from the size of a dime to the entire side of his face over night. Do a search on here for Moses hotspot and you can see pics and treatment recommendations. Vertericyn is handy to keep on hand. Something else to consider: Pythiosis of the skin (or cutaneous pythiosis) results in the development of swollen, non-healing wounds, and invasive masses of ulcerated pus-filled nodules and draining tracts. Tissue death (necrosis) follows, with the affected skin eventually turning black and wasting. Causes This infection is caused by direct contact with water that accommodates Pythium insidiosum, a water borne fungal parasite. It is usually swallowed or inhaled by the dog, and from there makes its way to the animal's intestinal tract. Register Now In order to be able to post messages on the German Shepherd Dog Forums forums, you must first register. Please enter your desired user name, your email address and other required details in the form below. User Name: Password Please enter a password for your user account. Note that passwords are case-sensitive. Password: Confirm Password: Email Address Please enter a valid email address for yourself. Email Address: Log-in User Name Remember Me? Password Human Verification In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.Q: Nested class AsyncTask can't modify Outer Class static objects I have a problem with Nested java class, it sees outer class object but somehow fails to modify it. I read a lot of similar questions but couldn't find solution for this one. It might be something really simple but I'm not good enough to figure it out. I have Sorter class to do some calculations in the background, I decided to use AsyncTask to perform those calculations outside of UI Thread. My class looks like this public class Sorter { private static List<Long> workingList; private static int _numberOfContainers, _containerSize, _timesToRepeat; private static Long _numbersFrom, _numbersTo, _sortingAlgorithmId; public Sorter(int numberOfContainers, int containerSize, Long numbersFrom, Long numbersTo, int timesToRepeat, Long sortingAlgorithmId) { _numberOfContainers = numberOfContainers; _containerSize = containerSize; _numbersFrom = numbersFrom; _numbersTo = numbersTo; _timesToRepeat = timesToRepeat; _sortingAlgorithmId = sortingAlgorithmId; // perform calculations in the background new BackgroundCalculations().execute(); } static class BackgroundCalculations extends AsyncTask<Void,Void,Void> { @Override protected Void doInBackground(Void... voids) { workingList = new ArrayList<>(_containerSize); // workingList is still null after this _numbersTo += 1; // to fix exclusive number range to inclusive Random rand = new Random(); for (int i = 0; i < _containerSize; i++) { workingList.add((long) (rand.nextDouble() * (_numbersTo - _numbersFrom)) + _numbersFrom)) } // some calc return null; } } } I tried to instantiate workingList in Sorter constructor but nested class fails to add items to workingList anyway. Any solutions? Maybe better way to implement background calculations without such problems? A: You are mixing up two concepts here. Your methods are all static; and your fields are two. So why do you then use a constructor; indicating that you want an object of your Sorter class to be instantiated? So, the first thing to fix your problem - get a better understanding of the concepts you are using. 515 F.2d 1181 dMoodyv.U. S. 75-1124 UNITED STATES COURT OF APPEALS Fifth Circuit 6/25/75 1 M.D.Ga. AFFIRMED Summary Calendar case; Rule 18, 5 Cir.; see Isbell Enterprises, Inc. v. Citizens Casualty Co. of N Q: I want to learn to play an electric guitar, how do I start? I'm 15, and recently I've watched a few electric guitar performances on YouTube. It got me really interested in electric guitars. Now, I've never played a guitar before, neither electric nor acoustic, i kind of did, I'll explain in a second. My grandfather owns a few acoustic guitars and he's pretty good at it. When i was 11 he taught me how to play Smoke on the Water, a pretty simple melody. I didn't practice that song much, I played it a few times for fun, what I'm trying to say is that I kind of know how a guitar feels on my lap and I know how it feels to play the strings. Apart from that, I never played them. I wasn't interested in guitars before, but recently I have. I don't like acoustic guitars, I like electric ones. Anyway, I have a question: I''m a beginner. I'd like to learn how to play an electric guitar. Should my first guitar be an electric or acoustic? Which one is easier to play and easier to learn to play? And a bit sillier one, could I cut my fingers on a guitar's strings? I'll be glad if someone answered my questions, I'm eager to learn how to play an electric guitar. A: I don't like acoustic guitars, i like electric ones. You should start with an electric guitar. There are arguments both ways to whether to start on electric or acoustic, but these differences are minor compared to enthusiasm. You won't get anywhere with a guitar that you don't like and don't play. You'll go far with one that gets your heart racing so you play it frequently. The strings on electric guitars are usually lighter and closer than acoustic. This is argued in favor of electrics as easier to get started on and in favor of acoustics as forcing better habits. If your grandfather is available I'd recommend taking him shopping for an inexpensive but well set up electric guitar and amp. There are dozens of sites with reviews of good starter guitars. The important thing when starting out is that it's set up well. A cheap but well set up guitar will play better and easier than an expensive but poorly set up one. Once you have the guitar take some lessons (or have your grandfather give you some if he's available and able to - playing and teaching are very different skills though) and find some like minded friends to play with. Locally a lot of the teen-oriented lessons also help the students form bands. If your friends aren't already interested in playing there may be something similar near you. Your fingers will be sore when you get started, but they shouldn't bleed. You'll need to build up strength and stamina. Take things slowly at first and stop when your fingers or hands hurt. A teacher will be able to help identify if you're hurting because of bad technique or if it's just from getting tired. Playing several 10-15 minute sessions is much safer and more valuable than one marathon session. A: Should my first guitar be an electric or acoustic? If you want to play electric, as you said, then your first guitar should definitely be an electric. Which one is easier to play and easier to learn to play? Stylistically, as in how people choose to play them, they are just a little different and neither is necessarily easier. But from a technical standpoint, assuming you chose to play the same thing on both, an electric is usually a little easier to play for most people because of the string gauge, action, and neck thickness. And a bit sillier one, could i cut my fingers on a guitar's strings? Just from playing them? No, not really. You might get blisters at first if you practice hard enough but eventually you'll build up calluses. And you can and probably will prick yourself on the strings ends at some point when changing strings. how do i start? Get a guitar Get a teacher Have them help you learn songs that you like because you'll make more progress if you're enjoying your practice time. Try to have a goal and keep that in mind at all times. For example if your goal is to play cover songs in a band with friends, then you should spend your practice time learning songs and playing with a band. But if your goal was something different you might spend your practice time on something else. Your practice time should always be moving you toward your goal. Home Theater Installer THX Home Theater 2 Professional Workshop Building upon the Home Theater 1 Workshop, this Home Theater 2 course provides in-depth training on room acoustics and design, wall treatments and isolation, and AV hardware selection and placement. Hands-on training techniques are incorporated into this comprehensive program – detailing system set up, speaker positioning and audio calibration. General Course Information The cost for this
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2042, 253, 1429, 310, 347, 13491, 347, 388, 3230, 449, 346, 5872, 352, 434, 12207, 449, 346, 1552, 310, 323, 479, 865, 346, 6067, 28806, 310 ]	go go" "I'll be back." "Manager!" "Do not eat that!" "Don't" "Hello" "Having a crush, You haven't reach puberty?" "You have that opportunity today." "You could have dated her." "Come on.." "I have my way.." "It's suffocating to death watching this." "Expert.." "Why do you get dump always?" "You punk!" "Mr. Yoon.." "From my observation." "You seem too withdrawn." "Really?" "To win her over, comply to Rule 369" "Ah.. what is that?" "Three." "Text her 3 times daily." "Six." "Reply 6 mins after she replied." "Nine." "After nine at night never reply." "Ah.." "Try to look tough today." "It's Christmas eve." "You guys dating?" "Madam Jung.. take a seat" "Today I give slight concession to you." "For that I have to thank you." "Why are you late?" "What?" "Turn off fire 3 mins later." "Remember to off it after 3 minutes" "Yeah ok" "Come with me." "Onions should be peel by hands." "My precious ring." "How dare he eat it?" "Bring so many tears to me." "Oh." "Fire!" "Fire!" "What happened?" "Call your call" "All in" "Ooo..his cards must be good." "Run away." "Hold it.." "I won it." "I won." "Hurry Hurry" "Yeouido personel dispatched now." "Announcement" "Teams 7 get ready to go" "I obviously won it!" "Come over Come over" "Byung-man you coming?" "Where's that card?" "Excuse me" "I am looking for the Chief?" "Take a look" "Who you are?" "What could be the problem?" "How do you people manage this place?" "Sorry about it." "Any incident in the kitchen." "You hold full responsibility" "Yes, I am responsible." "But the design basically have flaws." "Flaws?" "As you know there are many kitchen stoves." "Ventilation is so insufficient." "Without proper ventilation." "The guest might complain." "The design was not taken into consideration at all." "If there's fire big problem with the sprinklers." "How is that?" "Specific problems have to rectify." "I don't think there is any water in those sprinkler." "No?" "General Manager" "Supervisor Lee!" "Prepare the party, Prepare the party" "I say go prepare the party now!" "Just wait till the party's over!" "Reporting" "Firefighter.." "Lee Sun-Woo 24th December transferred to Yeouido Fire Department." "That is all, Sir" "Can you do a good job?" "Yes" "I want to be an outstanding firefighter." "Hmm.. outstanding Firefighter" "What is outstanding fireman?" "Ha ha Hmm.. this it's not just the inspiration, it's the will." "Outstanding firefighter.." "Byung-Man" "Let's go." "Coming?" "Firefighters should always be ready for rescue action." "And then?" "Explain" "From what I seen here today." "You guys are not prepared at all." "Idling away is work also." "But.." "This is your place now.." "Hopefully you will get used to it." "Hey.." "Get unpack and take a shower." "I should get the equipment, Why take shower?" "How to say this.." "Say on wedding night." "If your lover didn't take a shower." "Leaned over you, what will you think?" "I think she is not ready." "Yes precisly.." "You should get ready right?" "Go take a shower." "Get fresh and inspire." "I get equipments." "Is Captain Kang Young-Ki on duty today?" "Why look for him?" "In our school, he was a legend." "Legend not heard of me?" "What is your name?" "Ah.. forget it." "Knowing me, will give you the headaches" "Oh.. hello" "Thanks" "Thank you for helping me." "Ah..don't mention.." "It's small matter." "Is that not mistletoe?" "What is that?" "You don't know mistletoe!" "Christmas time anyone under the mistletoe gets a kiss." "Huh!" "Ah..really?" "I don't know this!" ".." "I didn't sit..sit here intentionally for that!" "That I.." "I..." "Are you burnt?" "Ha ha..no It's tastier when the coffee is hot.." "Ha ha" "Are these marble?" "It' definitely not bricks. haha" "Church Elder Kim.." "This is like Paradise." "This is the Paradise" "Once you started working, you will know 90% of firefighters in the field knows nothing." "You listening to me?" "Yes ..yes listening." "Tell you this.." "Fire fighting, rescue and evacuation only a few are really good at these three." "Only person who are the expert with these. that's me." "Since you are following me." "You will soon become a real fireman." "What are you doing?" "We have got to go!" "I don't have any equipment yet." "Senior" "Senior" "Hello" "Senior" "Hurry up kid" "Senior" "Ha ha ha ha" "Congratulation" "Congratulation" "We welcome Lee Sun-Woo joining us" "Congratulate" "Stand attention" "Welcome to our team." "Woooh.." "Stand at attention." "Hands down." "Hands down." "Wow!" "Nice!" "Surprised?" "Uncle grow up!" "It's childish." "Where is dad?" "He is up to something." "Hana, you want to meet a woman who your father like?" "Father like?" "60th floor" "There is no water." "Where does the pipe connected to?" "Last year, It was retro-fitted to building's external right to the 80th floor." "Why like this?" "It's no big deal.." "What could possibly happen?" "You aware of the party tonight right?" "Be back home early ok..ya..?" "Sorry ma'am" "Kindly dispose the poo." "So what?" "House rule owners must clean up." "Ahh!" "Aunty.." "Why don't you clean it." "That is why they pay you right?" "Yes.." "Ok I will clean for you once." "But the next time you do it." "My Oh My..." "How dare you threaten me!" "Aunty.." "You!" "What's your name?" "Ms... sorry ma'am" "I am asking." "What's your name?" "Fun?" "Why is father so busy?" "Ah..as always" "Manager" "Manager" "I know the reason why." "The pipes are frozen from 60-80 floors there is no water" "Before the problem is fixed we have to add more fire extinguishers" "Supervisor Lee" "Can't you see everyone is busy?" "Sprinkler, extinguisher, no water." "Come on ..we have a party." "You don't know what is more important?" "Manager" "Manager" "Sorry.." "Director Jo" "Why the sudden cancelation of the Chopper flights?" "I was told, there will be high winds," "Strong turbulent wind." "Strong winds?" "How do we deal with this?" "Contact Disaster Prevention Department." "Yes" "Will call Disaster Prevention for Aviation." "Why Aviation Department?" "They control chopper flights." "Forget it." "Call Mayor of Seoul personally." "Understand." "Hana" "Daughter.." "Always like this." "Dad has to ensure the safety in this building." "Sorry.." "Just wait a little longer please." "Oh my.." "let me..move can't even make a child happy." "Hana dear" "Ah..you rascal.." "Why make her cry?" "Hana" "What happen?" "Hana what happen?" "Father.." "He" "Not accompanying me, wants to work." "What to do?" "We have to check the sprinkler for water." "Do you mind taking care of her?" "Miss Yun Hee is busy too." "We are busy." "Let's go." "Hana be good, listen to sister ok?" "Want to know why she cries?" "Hana will be an actress when she grows up." "What do you mean?" "I told her, if she wants Yun-Hee to play pretend to cry." "This kid is really good at crying." "With Yun Hee handed over to Hana." "Will surely succeed." "Hana the matchmaker," "Will matchmake the both of you.." "Great?" "Sister, Man of what Zodiac do you like?" "Gentle or Beastly type?" "What is your blood group?" "My dad is O" "Bachelor with a daughter possible?" "About this.." "A gentleman or O blood type is ok." "But have a child, I don't think so." "But" "If the child is as lovely as Hana." "Then it's acceptable." "This is for me?" "Our princess is
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380, 14645, 7009, 9724, 310, 38089, 275, 4685, 253, 2448, 1039, 273, 253, 12553, 14232, 15, 7047, 1206, 366, 26729, 187, 187, 39419, 1402, 2506, 457, 85, 871, 752, 368, 457, 250, 5015, 670, 15, 3032, 1416, 3548, 457, 85, 247, 19080, 314, 49932, 5419, 4543, 310, 521, 3665, 11797, 407, 643, 29502, 38330, 16596, 15, 16456, 1402, 457, 84, 521, 1211, 637, 285, 326, 457, 84, 625, 685 ]	of Iran's regime and they are growing politically powerful in their own right - the new president represents " the pasdaran party". They are not completely under Khameini's control and they - or at least factions within the Pasdaran - are spoiling for a fight with American and western interests. Other factions have been more pragmatic and provided America's IC with a good deal of useful intel on the Taliban and pre-war Iraq. Juan Cole dismisses the possibility of cooperation between al Qaida and the Pasdaran in Iraq or elsewhere. Generally Shiite-Sunni radicals would regard each other with great antipathy so as a rule of thumb that's fine but state and factional interests are also at work. I think that Cole, at best, has an unproven assumption since neither Iran's government nor al Qaida appear to be very homogenous. Their internal decision-making process is opaque and relationships are murky and often-times transient. Saddam talked to al Qaida, so does Iran, so did/does Pakistan, the Saudis and probably many, many others who are our allies. Iran has helped both secular and religious Sunni Arab terrorist groups in Palestine and the Iranian border is porous both in Azerbaijan-Kurdistan and in Baluchistan in the east. Who really knows what local Pasdaran authorities might be up to ? Or criminal gangs that might be cut-outs and smugglers for all comers with cash to pay ? Hard to know the players and their motivations without deep expertise which I do not have. Iran is run by bad people. Some of them are reckless idiots and some are cautious and pragmatic. Others are corrupt. That's what we have to work with and our best ace in the hole is that an Iraq engulfed in total civil war is on Iran's doorstep and not ours. So uncomfortably, there is some degree of common interest with Iran but not a lot.Abstract Systematic reviews constitute the highest quality of evidence and form the cornerstone of evidence-based medicine (EBM). Such reviews now inform everything from national health policy guidelines to bedside care. However, systematic reviews are extremely laborious to produce; researchers can no longer keep pace with the massive amount of evidence now being published. Semi-automation of systematic review production via machine learning (ML) has demonstrated the potential to substantially reduce reviewer workload while maintaining comprehensiveness. However, it is unlikely that machines will fully supplant human reviewers in the near future. Rather, human experts will probably remain in the loop, assisted by automated methods. Methods that exploit the intersection of human workers and ML models in the context of systematic reviews have not been explored at length. Furthermore, we believe there is substantial untapped potential in harnessing distributed crowd-workers to contribute to systematic reviews, and thus economize expert reviewer efforts. This novel avenue has largely been neglected as a means of increasing the efficiency of review production. We propose addressing this gap by developing and evaluating novel, hybrid approaches to generating systematic reviews that jointly incorporate domain experts (systematic reviewers), layperson workers recruited via crowdworking platforms such as Amazon's Mechanical Turk and volunteer citizen scientists, while simultaneously capitalizing on ML models. This innovative, hybrid approach will be the first in-depth exploration of intelligent ML/human systems that aim to reduce the workload in the production of biomedical systematic reviews. Our strong preliminary work demonstrates the promise of this general strategy.Balenciaga, fw17/18 The Fashion Alphabet today is about D, like Down Jacket. Brilliant ideas, especially in creative environment, can often originate from a real necessity, or even from an avoided tragedy. In this case we are in Alaska in 1935, during a fishing trip, with Eddie Bauer about to have hypothermia. He, after having risked his life, understands and decides that, for some freezing temperatures, wool wasn’t enough, opting for a lined jacket that’s light at the same time; so, thinking about Russian Army’s jacket, ha created a warm and waterproof piece of outerwear, padded with goose down, with diamond shaped seams in order to keep the padding fixed and tight tobthe body. Patented in 1940, it becomes popular in ’42, thanks to the B-9, the jacket for USA air force, able to keep warm with an outside temperature of -56°C. Then is the turn of Moncler, that in ’52 establishes the company, at first producing tents, sleeping bags and one model of hooded cloak: a cloack that during the years, transforms itself becoming the core business of the company and then an iconic and timeless garment. Paninari, in the 80s, elect the down jackets as their distinguishing feature, matched with Best Company sweatshirts and Timberland boots, wearing all types of them, made of shiny nylon, oversized, in bright colors. The down jacket, in those years, is no more perceived as a purely technical garment for mountaineering and skiing, but becomes a symbol, recognizable and categorizable, of a precise group in terms of identity and style. Anyone remembers the “cinepanettone” movies in the 90s, starring Jerry Calà, Ezio Greggio, Christian de Sica and Massimo Boldi wearing in the many “Vacanze di Natale” (Christmas Holidays) huge and colored down jackets, matched with bad taste, during their adventures/misadventures in the mountains. Today we can say that fashion has transformed the down jacket with so many shapes, weights, materials and colors, that we are far from those years, when we were children and we felt like the “Michelin Man”, clumsy and ugly, forced by our mothers to go out dressed that way because “it was cold”. From sport, to movies, to catwalks, the step was short, and the down jacket is now a fashionable garment, as important as a coat or a blazer in a man’s wardrobe, presented also by niche brands like Comme des Garçons, Rick Owens, Raf Simons and Balenciaga. With Balenciaga and with his brand Vetements, the new, young creative director, Demna Gvasalia, imposes through his fashion shows the use of the down jacket, in very bright- almost unmatchable- colors, bulky and unstructured, for fall/winter as well as spring/summer; due to his contribution also, for fashion victims, now than ever, the down jacket has become a must-have and the characterizing part of a cool and modern look. In the picture for The Men Issue by Federico Miletto, the down jacket (Fall/Winter 17/18 Moncler) made of black shiny nylon with maxi pockets, is matched with a cotton hooded tracksuit and a wool beanie, in the classic sport mood; as always, the streetstyle shot aside shows a way of wearing it which is casual, but urban and cool at the same time. In the following gallery, instead, there are several looks from f/w 17/18 fashion shows – with some previews from spring/summer 18 – of great designers, that present sleeveless, printed, short, long, hooded or not down jackets. Giovanni de Ruvo Alessandro Calascibetta has been active in fashion since the late 80s. He started off his career at L'Uomo Vogue, after that with Mondo Uomo. Afterward, he became Fashion Director at Harper's Bazaar Uomo, and in 2000 founded Uomo which he directed until 2003. Following that, he started collaborating with Rizzoli. Since january 2015 he is the Editor in Chief of Style Magazine, and still remains as Man Fashion Director for Io Donna and Sette.The death penalty arouses our passions as does few other issues. Some view taking another person’s life as just and reasonable punishment while others see it as an inhumane and barbaric act. But the intensity of feeling that capital punishment provokes often obscures its long and varied history in this country. Now, for the first time, we have a comprehensive history of the death penalty in the United States. Law professor Stuart Banner tells the story of how, over four centuries, dramatic changes have taken place in the ways capital punishment has been administered and experienced. In the seventeenth and eighteenth centuries, the penalty was standard for a laundry list of crimes—from adultery to murder, from arson to stealing horses. Hangings were public events, staged before audiences numbering in the thousands, attended by women and men, young and old, black and white alike. Early on, the gruesome spectacle had explicitly religious purposes—an event replete with sermons, confessions, and last-minute penitence—to promote the salvation of both the condemned and the crowd. Through the nineteenth century, the execution became desacralized, increasingly secular and private, in response to changing mores. In the twentieth and twenty-first centuries, ironically, as it has become a quiet, sanitary, technological procedure, the death penalty is as divisive as ever. By recreating what it was like to be the condemned, the executioner, and the spectator, Banner moves beyond the debates, to give us an unprecedented understanding of capital punishment’s many meanings. As nearly four thousand inmates are now on death row, and almost one hundred are currently being executed each year, the furious debate is unlikely to diminish. The Death Penalty is invaluable in understanding the American way of the ultimate punishment.Filtrate Shop Banray doesn’t know what you’re talking about. His name isn’t a cleverly disguised pun nor is his frame inspired by other sunglasses manufacturers. Banray’s his own man and that’s more than
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933, 2556, 281, 18371, 67, 3750, 313, 19, 15, 1348, 558, 1335, 15423, 604, 13, 347, 556, 644, 9125, 13, 326, 4677, 943, 320, 15045, 32372, 281, 670, 854, 1976, 13, 933, 1108, 1077, 11467, 13, 253, 4668, 14, 486, 637, 9177, 273, 14890, 390, 5791, 25939, 571, 3063, 15, 187, 187, 4553, 1052, 13, 342, 32316, 2439, 253, 21609, 432, 11268, 281, 10497, 31279, 13, 3904, 3517, 2427, 598, 969, 27, 689, 21990, 13, 933, 275, 21732, 28, 275, 253, 1390, 807, 273, 253, 12245, 40549, 33286, 3660, 13, 1335, 670, 7783, 13, 933, 28, 285, 275, 21640, 13, 672, 2639, 394, 486, 285, 41118, 497, 256, 16970, 13, 253, 18500, 285, 1249, 1791, 621, 313, 14382, 1024, 608, 13, 5388, 2266, 285, 342, 38952, 21745, 592, 281, 3761, 10, 2264, 264, 11467, 253, 1072, 969, 15, 6000, 9976, 875, 19956, 285, 21640, 313, 262, 556, 644, 16505, 11406, 10, 574, 387, 1878, 854, 2558, 13, 285, 1309, 253, 6347, 25150, 280, 3660, 598, 281, 3285, 2558, 13, 273, 30396, 10652, 1668, 285, 689, 275, 6174, 15, 496, 1614, 13, 2167, 15245, 14, 936, 14, 455, 728, 9296, 3783, 12848, 1309, 253, 1072, 8007, 13, 253, 11684, 1160, 327, 14310, 968, 285, 9890, 10621, 74, 588, 452, 644, 642, 21259, 285, 2223, 497, 27953, 15, 187, 187, 52, 4078, 369, 3021, 2137, 14, 468, 1405, 456, 327, 14257, 247, 9928, 3720, 15, 5595, 30396, 285, 40300, 2458, 1364, 13, 751, 45494, 461, 30264, 13, 452, 2326, 4668, 2579, 3746, 390, 574, 48729, 3767, 665, 858, 594, 13, 390, 1097, 15, 21, 187, 187, 20, 22887, 41767, 275, 253, 6495, 14848, 187, 187, 6872, 1270, 4430, 19491, 574, 1095, 8140, 42455, 43203, 275, 253, 2626, 5331, 285, 840, 253, 1273, 15, 380, 806, 767, 25150, 280, 14848, 497, 2761, 23737, 4087, 19983, 275, 4852, 15, 17436, 1507, 275, 253, 3973, 25150, 280, 3660, 497, 4092, 10502, 13, 6701, 281, 295, 1920, 474, 29257, 8292, 1255, 285, 313, 34295, 40650, 10, 9054, 10861, 15, 18371, 67, 3750, 8, 25186, 8442, 13, 390, 690, 273, 731, 13, 452, 644, 13282, 13, 533, 5536, 6215, 14, 395, 10402, 14, 18585, 265, 858, 2826, 13, 347, 5393, 1840, 15, 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7527, 13, 751, 253, 32540, 32818, 14, 8777, 275, 253, 45494, 321, 757, 28214, 273, 11186, 9972, 13, 275, 322, 472, 41214, 285, 49480, 3737, 13, 285, 2439, 253, 47829, 1420, 275, 11090, 314, 5182, 285, 18363, 2056, 571, 28, 2223, 2217, 13, 597, 497, 42652, 407, 247, 2087, 31702, 7491, 90, 13, 20086, 13, 285, 1289, 20130, 15, 187, 187, 21, 6049, 858, 30396, 40402, 32, 187, 187, 18812, 497, 3264, 281, 5752, 21609, 14, 4363, 13, 347, 45494, 461, 30264, 8, 3307, 18120, 17093, 15, 831, 369, 247, 4735, 326, 8907, 285, 4231, 382, 27619, 2335, 323, 7169, 15, 1583, 2335, 323, 7169, 13, 1512, 13, 326, 2104, 14, 39455, 728, 1821, 651, 5752, 13, 1880, 347, 15986, 390, 347, 772, 1687, 84, 15, 831, 36543, 2137, 14, 88, 3867, 1255, 273, 253, 9826, 15245, 369, 581, 273, 253, 1142, 30450, 326, 3534, 253, 8370, 285, 9890, 7888, 616, 49258, 10458, 14542, 13, 347, 32766, 34300, 6888, 285, 18371, 67, 3750, 9791, 3013, 15, 187, 187, 9147, 363, 3875, 5684, 273, 247, 13699, 869, 5182, 3534, 8370, 13, 285, 13353, 1512, 9890, 13, 9647, 247, 2714, 17985, 902, 15, 18371, 67, 3750, 24631, 352, 275, 247, 4499, 342, 253, 2639, 394, 26093, 2458, 27, 187, 187, 60, 510, 2639, 394, 26093, 2458, 62, 897, 5639, 285, 14480, 35634, 5621, 13, 533, 253, 30396 ]	32.6). Indeed, Ligustinus and his comrades wanted to serve, but in their old posts as centurions. In 149 the consuls had no trouble calling up men for the Third Punic War because booty lured (Appian, Pun. 75.351) – a notable contrast with the resistance to levies for Spain just two years earlier (below). But sometimes the authorities had to compel enrolment. Warfare that brought mere toil and risk, without counterbalancing rewards, rarely appealed. Compulsion was required, for instance, in 193 for a campaign against Ligurian mountaineers, and in 169 as Ligustinus' no-longer-enticing war dragged on (Livy 34.56.1–2, 43.14.6–7). In such wars, serving soldiers sometimes – rightly – felt exploited and they complained. It happened in Spain in 206, when a corps mutinied outright for a time (Polybius 11.25–30; Livy 28.24–29), and there again in 180 under one of Ligustinus' commanders, Fulvius Flaccus (Livy 40.35.5–7, 36.4, 36.10–11). Spain was an unpopular theater: the wars were hard, dangerous and, after the first three decades of Roman rule exhausted the readily available loot, mostly unprofitable. The outbreak of yet another Celtiberian war in 151 deterred even prospective young officers from volunteering, until Africanus' grandson Scipio Aemilianus set the example (Polybius 35.4.2–14; Livy, Per. 48).2 2 The Impact of Military Service The economic and demographic impacts of these international wars are explored elsewhere. Here it is important to stress how constant a feature they were in Romans' and Italians' lives: a point well illustrated by Ligustinus' career. The regular demands for experienced recruits were one effect of another feature of Roman wars after 264: the unprecedented size of forces in service. Warfare had been a regular feature of Roman society from the outset, as Roman tradition itself recognized. The temple of Janus was closed, as a mark of total peace, supposedly only twice before Augustus' time – under King Numa (Livy 1.19.3) and in 235. But war-service from the third century on became more enduring and more large-scale. Third-century legions consisted, in principle, of 4,200 Roman infantry and 300 cavalry (the latter recruited from well-to-do citizens), plus Latin and Italian allied troops up to twice these numbers. In the First Punic War two consular armies, each two legions strong, were levied yearly. From 261 until 249, and then again in 242–241, further recruits were needed for the Romans' ventures on the sea, mainly drawn not from Roman citizens but from their maritime Italian allies. On a conservative calculation, the fleet sent to invade Africa in 256 was manned by 69,000 crewmen; the one raiding Africa in 253 had nearly as many, and in 249, when two consular fleets suffered disasters thanks to the enemy and the elements, their combined crews may have exceeded 80,000 men. The demands these efforts put on manpower were notable. When a big fleet and the legions both campaigned, as in 256 or 249, peninsular Italy had over a hundred thousand able-bodied men at war. On a rough estimate, in such years over 12 percent of available males were in arms. This was an unprecedented effort, although discontinuous and although its effects remain obscure.3 Even heavier demands ensued. There were some 155,000 men called up in 225 to face the Gallic invasion, and nearly as many (145,000 or so, for armies and fleets) at the start of Hannibal's war. At the height of this, in 212–211, with 25 legions in Italy, Cisalpine Gaul, Spain, and Sicily, and over 200 warships in commission, the total of Romans, Latins, and Italians under arms has been calculated at about 233,000. Even in the war's last year the republic's forces totaled around 110,000. These were extraordinary figures for a peninsula whose available manpower shortly before 218 totaled 770,000 according to Polybius (2.24); still extraordinary if, as has been argued, that figure should be corrected upwards to about 875,000 – very roughly, the military-age manpower of Iowa or East Anglia today. After 200, with commitments across the Mediterranean from Spain to Asia Minor, numbers soon went up again: over 212,000 in 190; in the last year of the Third Macedonian War, still about 150,000; and in 146, when Carthage and Corinth were sacked, the fleet and 12 legions (each now 5,500 strong and with allied contingents to match) totaled roughly the same again. Every decade between 225 and 146 (it has been reckoned) had at least 8 percent, and during the Second Punic War up to 29 percent, of Romans aged 16 and over in arms. In turn, though citizen-to-alliedratios varied during the same decades, the demands made on Latins and Italian socii will have been no lighter and often were heavier. Society was thus war-permeated on virtually a permanent basis. Most Romans and Italians must, like Ligustinus, have seen military service themselves or had kinsmen who did so, or both.4 3 Risk Levels in the Great Wars These great armaments had curiously contrasting fortunes in the third century and then the second. The first two Punic Wars were almost ruinously costly in lives. Fleets in the First Punic War were serious risks, thanks to nautical inexpertness and (occasionally) enemy skill. Polybius' naval figures, or some of them, have been suspected, but heavy ship-and crew-losses did occur, as mentioned above. Losses at sea hit the Italian socii especially hard, with the maritime allies providing most of the crews. In the Second Punic War, it was Roman armies which suffered catastrophes, not only in Italy but also in Cisalpine Gaul and Spain. Even if Roman losses at Cannae, for instance, are estimated downwards (not entirely convincingly) to 30,000 killed besides the 10,000 captured – and likewise Appian's claim (Pun. 134.635) that Hannibal destroyed 400 Italian cities and slew 300,000 enemies – yet the Italian peninsula and especially its southern half suffered badly from 15 years of warfare. Roman territory itself, outside Campania, was not heavily harmed after 217: yet the census of 203, carried out with particular care (Livy 29.37.5–6), returned only 214,000 citizens (though it did omit several thousand now-disfranchized Capuans and other Campanians). The impact on the loyal Italian populations must have been proportionately harsher, while those who had defected not only had to provide forces for Hannibal's war-effort but later suffered for this at the Romans' hands.5 The wars following were a revolutionary contrast. None in the East lasted more than four years. Roman casualties were far fewer: 700 killed, as against 8,000 Macedonians, at Cynoscephalae in 197, in which Sp. Ligustinus no doubt fought (Polybius 18.27.6; Livy 33.10.7); allegedly 324 at Magnesia in 190, where Antiochus III was crushed (Livy 37.44.2); and, Livy affirms, 100 – mostly Italian socii – at Pydna in 168, where 20,000 Macedonians died (44.42.7–8). Defeats could occur – a notable setback at Callicinus in 171 against the Macedonians, for instance (42.57–60) – but none was shattering. There were few naval actions and no major disasters. Even allowing for deaths from wounds, skirmishes, and ailments, Roman forces in eastern wars must have come to feel almost damage-proof as well as invincible. Although Spanish wars after 201 had fewer clear-cut endings – but instead much marching, many sieges, and opponents widely spread out and frustratingly resilient – Roman forces were smaller (usually a legion in either province), losses much lower, and a quarter-century, from 179 to 154, largely peaceful. Other second-century wars were small-scale, like the intermittent flare-ups in the Ligurian Mountains of northern Italy, in Sardinia and Corsica, and across the Adriatic in Illyria and Dalmatia; often enough, they were provoked by a general chasing booty, slaves, and gloria. 4 Why did Romans Fight? Men were expected to serve Mediterranean-wide, as Ligustinus' 22 campaigns illustrate. This was a feature that Senate and magistrates took for granted. They took for granted, too, that able-bodied men would serve, whether as volunteers or as conscripts. This enduring war-willingness of the ordinary citizen was one of the many strands that gave the Roman and Italian communities their extraordinarily tough texture, as Hannibal discovered and Polybius praises. Patriotic defense of a threatened patria gave Roman, and surely too Italian, soldiers a special esprit. Polybius stresses it in a contrast with the Carthaginians: [The Carthaginians] use foreign and mercenary forces, but the Romans
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49762, 19699, 64, 686, 84, 806, 3578, 2607, 323, 9311, 275, 247, 2014, 4644, 275, 253, 2965, 273, 23430, 15, 754, 671, 4821, 281, 789, 327, 747, 5312, 795, 49762, 19699, 64, 22486, 13, 3798, 387, 2360, 15, 322, 2835, 387, 521, 8597, 285, 10470, 247, 19555, 13, 7902, 651, 3630, 285, 3812, 432, 1903, 27, 361, 387, 2360, 1919, 608, 27, 361, 253, 1735, 4131, 15, 754, 3798, 5262, 767, 15513, 4028, 253, 2129, 434, 6001, 13, 3560, 407, 767, 15513, 10263, 253, 22486, 15, 13168, 344, 369, 3515, 594, 3563, 326, 387, 721, 27, 361, 275, 253, 4131, 13, 344, 651, 3324, 521, 22486, 13, 12296, 1335, 9685, 13, 281, 521, 6346, 8679, 32433, 437, 13, 665, 651, 5926, 731, 745, 387, 253, 5365, 31181, 9038, 327, 253, 1039, 281, 521, 2628, 275, 1457, 2816, 3228, 15, 6975, 521, 1894, 13, 29271, 13, 7902, 15494, 327, 521, 3745, 281, 1965, 87, 885, 762, 3473, 15, 3771, 347, 13, 672, 10805, 745, 247, 28900, 13, 29271, 11359, 346, 8701, 259, 953, 285, 521, 19445, 260, 1402, 251, 3, 285, 21354, 2994, 247, 23470, 13, 594, 253, 17682, 20639, 7106, 7902, 434, 19311, 13, 4900, 2996, 521, 17368, 387, 2360, 15, 187, 187, 817, 898, 50276, 187, 34, 29638, 31250, 4889, 38164, 29638, 411, 37272, 187, 187, 5872, 13, 253, 637, 285, 253, 3226, 755, 7028, 15, 187, 187, 3726, 2186, 3564, 187, 187, 395, 597, 9549, 1728, 187, 187, 1128, 9896, 24318, 5918, 24318, 5918, 24318, 5918, 24318, 187, 187, 9896, 24318, 5918, 24318, 5918, 24318, 5918, 24318, 1128, 187, 187, 36776, 15, 187, 187, 1128, 51, 19366, 611, 5214, 24001, 13, 795, 49682, 32867, 434, 20473, 19128, 285, 5131, 46155, 432, 12757, 64, 313, 36265, 10, 187, 187, 39993, 434, 2444, 3082, 5486, 326, 344, 285, 25635, 4934, 1077, 1027, 3038, 15, 25635, 9461, 387, 5093, 275, 253, 4131, 13, 846, 534, 703, 651, 1379, 616, 767, 9097, 323, 247, 2940, 2112, 253, 14263, 43183, 7121, 15, 3900, 344, 21567, 13, 25635, 3407, 2444, 327, 2926, 5697, 275, 617, 24311, 11803, 15, 16908, 9461, 387, 23483, 13, 285, 25635, 4229, 521, 12561, 285, 617, 11157, 13515, 17096, 15, 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13, 1928, 13, 285, 21319, 387, 2176, 11880, 13, 403, 28071, 27039, 937, 285, 841, 12342, 497, 346, 81, 974, 1037, 347, 3076, 347, 5492, 14, 3456, 6881, 547, 13, 14751, 1411, 2255, 13, 16618, 13, 3966, 449, 30164, 1316, 8042, 281, 346, 783, 29490, 13153, 16869, 273, 253, 1986, 2077, 285, 6144, 3, 347, 5877, 346, 290, 603, 314, 1027, 12342, 670, 1711, 952, 1381, 346, 19799, 841, 16869, 13, 253, 1029, 1127, 273, 18109, 2825, 310, 1711, 14, 486, 13, 670, 28089, 281, 32700, 15, 1422, 1472, 6326, 281, 320, 18109, 840, 28, 594, 13, 17912, 13, 368, 403, 18109, 840, 449, 11474, 24152, 13, 23060, 27621, 858, 417, 1158, 253, 2934, 4307, 347, 247, 2926, 15, 187, 187, 36, 16249, 3592, 7902, 342, 253, 3835, 10263, 323, 795, 49762, 19699, 64, 313, 4257, 2816, 27, 44842, 13, 23430, 481, 10882, 23633, 273, 253, 6212, 1665, 757, 39432, 15, 2719, 83, 26082, 342, 253, 9214, 273, 253, 22301, 273, 25635, 30164, 1316, 13, 19498, 309, 15, 3619, 293, 6339, 13, 12138, 6854, 15, 1876, 12484, 32997, 15, 187, 187, 9917, 275, 4437, 23430, 13, 8966, 44842, 3863, 795, 49762, 19699, 64, 1157, 9745, 253, 31556, 273, 253, 7060, 873, 281, 247, 14200, 8446, 15, 9384, 4714, 12808, 26108, 346, 36, 16249, 3592, 7902, 434, 15585, 4685, 273, 253, 20162, 273, 253, 1429, 13, 273, 8228, 8777, 285, 273, 33784, 7122, 13453, 84, 449, 7252, 12447, 6029, 11524, 13, 665, 1912, 253, 22420, 26386, 13412 ]	850 papers at that time.) As Johnson observed in late 1942, "If _Dick Tracy_ were dropped from the _News_ , 300,000 readers would say, 'Oh dear!' But if Barnaby went from _PM_ , his 300 readers would write indignant letters." Though it never had a mass following, _Barnaby_ was by 1943 already earning Johnson five thousand dollars per year. Crockett Johnson, illustration from Constance Foster, _This Rich World: The Story of Money_ (New York: McBride, 1943). Reprinted with the permission of the Estate of Ruth Krauss, Stewart I. Edelstein, Executor. All Rights Reserved. In the spring of 1943, Johnson's career branched in another direction when he illustrated his first children's book, Constance J. Foster's _This Rich World: The Story of Money_. Along with Ruth Brindze's _Johnny Get Your Money's Worth_ (1938), _This Rich World_ is one of the first wave of children's books inspired by the consumer movement, designed to educate children about money and the marketplace. Expressing Foster's understanding that "many of our problems are economic at root," _This Rich World_ is also the sole children's book to display any hint that Johnson was once a _New Masses_ editor. One illustration notes that "Millionaire Cadwalader and thirty-dollar-a-week Tom Kent pay the same indirect taxes," a not-so-subtle criticism of the flat nature of the sales tax. Another suggests the precariousness of an economic system built on borrowing. One man in a suit gives a thousand-dollar deposit to another man in a suit, identified as banker. The banker then gives a thousand-dollar loan to another man in a suit, who gives a thousand-dollar check to the first man. For her part, Krauss soon became annoyed that when a student did research, the professor's name went on the publication. Moreover, her anthropological work made her acutely aware that children quickly absorb the values of their culture; effecting change would require reaching children early in life. When she discussed this idea with one of her friends, the friend responded, "You should be writing for children and not doing this." Inspired, Krauss started writing a book that she hoped would give children progressive ideas. She undertook an anthropological examination of prejudice that would teach children about the dangers of fascism and anti-Semitism. She took her manuscript to Harper and Brothers, riding the elevator up to the office of Ursula Nordstrom. Nearly a decade younger than Krauss, Nordstrom had joined Harper in 1931 and had become director of the Department of Books for Boys and Girls in 1940. When Krauss stepped off the elevator, she met Nordstrom's assistant, Charlotte Zolotow, who was supposed to screen visitors. Zolotow remembered a young woman with "disheveled hair," an "off-beat" sense of humor and "perspective about life," and obviously strong "feelings for children." After a few minutes, Zolotow went into Nordstrom's office and said, "You've got to see her, you've _got_ to see her!" Nordstrom and Krauss then talked for a long while. After Krauss left, Nordstrom told Zolotow, "She's wonderful, and she's going to write a book for us." But it would not be the manuscript Krauss had brought with her: "That was a life of Hitler, and I didn't think that would do for the children's book world." Before the end of World War II, children's books that tackle prejudice are rare. In the wake of the war, Ernest Crichlow's illustrations for Jerrold and Lorraine Beim's _Two Is a Team_ (1945) show black and white children who are best friends. H. A. and Margret Rey, the creators of _Curious George_ and acquaintances of Krauss and Johnson, created _Spotty_ (1945), in which spotted bunnies and white bunnies learn to get along. Ruth's manuscript was still a couple years ahead of the curve. Johnson, too, was working on what would become his first published book, revising and redrawing the best episodes of _Barnaby_ 's first ten months for publication in a single volume in the fall of 1943. He also continued to work on new daily _Barnaby_ strips, usually at night. Sitting at his desk and smoking a cigarette, Johnson would write and draw from 11:00 at night until 5:00 the next morning. He usually spent two nights writing the week's script, followed by two nights drawing the strips. Sometimes he was running so late that at 6:00 in the morning, he would bring his strips, ink still wet, to his neighbor Bob McNell, who would drop them off at the PM Syndicate on the way to his job in New York City. Like his character, Harold, Johnson relied on his ability to improvise under pressure. Just as, when falling off a cliff, Harold keeps "his wits and his purple crayon" and draws himself a balloon, so the approaching deadline focused Johnson's wit, igniting his imagination at night. ## 9 A GOOD MAN AND HIS GOOD WIFE Then, the man and the girl get married. They hold hands and they ride home —galoop galoop galoop galoop galoop galoop galoop galoop— together. —RUTH KRAUSS, _Somebody Else's Nut Tree and Other Tales from Children_ (1958) Dave's working methods meant that he and Ruth kept very different hours. Ruth rose at seven in the morning, after which she would take their two dogs for a walk along the Five Mile River. While he slept, Ruth began working on story ideas in her upstairs studio. Dave rose at noon, and Ruth fixed his breakfast and her lunch shortly thereafter. Then he would read for about two hours before working in their Victory Garden or going sailing while she swam. At 5:30, they had dinner, prepared by Ruth. Dave would start work on _Barnaby_ at 8:00 but found that he only really got under way after the 11:00 news. Despite living in different personal time zones, they were a very close couple—so close that, on 25 June 1943, they got married in New London, Connecticut. Harper gave Krauss a three-hundred-dollar advance and a contract for her first children's book in October 1943. Influenced by her work on Ruth Benedict's anthropological project on south Italian farming families, _A Good Man and His Good Wife_ offers a novel twist on folktales that mock a husband's failed attempts to copy his wife. In contrast, Krauss has mimicry supporting the husband's efforts to teach a lesson to the wife. Nonetheless, as Krauss admitted four years later, _A Good Man and His Good Wife_ "made some mistakes" because "the characters are cast in the conventional roles." The "good man" can never find anything because his good wife keeps moving things around, explaining, "My dear, I get so tired of the same things in the same place." Frustrated, he puts his shoe on his head, his garters around his neck, his tie around his knee, his pants on his arms, his coat on his legs, his spectacles on his elbow, and his socks on his ears. He then sits on the breakfast table, eating his napkin and wiping his face with a biscuit. When his wife exclaims, "My dear, this is ridiculous!," he replies, "My dear, I get so tired of the same things in the same place." The tactic cures "his good woman of a bad habit": she stops moving things around. Ad Reinhardt, two-page spread from Ruth Krauss, _A Good Man and His Good Wife_ (New York: Harper, 1944). Reproduced courtesy of Anna Reinhardt. Copyright © Anna Reinhardt. Ad Reinhardt received the same advance and worked up a rough dummy of the book while Krauss pondered her next project, an anti-ageist children's book, _I'm Tired of Being a Grandma_. Ursula Nordstrom found parts of the beginning amusing but considered the manuscript "forced" and "not a really good follow-up to _A Good Man and His Good Wife_." Krauss persisted, sending Nordstrom two new versions of the story because "our concepts of how people think, feel, and behave at certain ages, are socially conditioned," and these concepts were "practically as bad as race-prejudice, prejudice against women, immigrants, etc." Krauss pointed to "the Northwest Coast Indians of the United States and Canada" as holding "entirely different concepts about old people": "Among these Indians, the high point of romantic sex is old-age, about seventy to ninety. You're supposed to be romantic then; so, consequently, you are romantic then." Though sympathetic, Nordstrom did not think the idea worked as a story. Crockett Johnson with the cover drawing for _Barnaby_ (New York: Holt, 1943). Image courtesy of the Smithsonian Institution. Reprinted with the permission of the Estate of Ruth Krauss, Stewart I. Edelstein, Executor. All Rights Reserved. Also in October 1943, Henry Holt published _Barnaby_ , bringing the darling of the smart set to a wider audience. Rockwell Kent praised "Crockett Johnson's profound understanding of the psychology of the child, of grownups and of fairy godfathers." William Rose Benét, who won the 1942 Pulitzer
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3830, 393, 2407, 92, 42, 889, 918, 10, 1227, 73, 5, 581, 4720, 31326, 1764, 4635, 14680, 1124, 92, 18, 1217, 47, 889, 2204, 1126, 1906, 426, 18, 1990, 47, 889, 1124, 464, 1274, 9, 393, 2407, 92, 34, 4689, 1906, 47260, 45, 889, 3830, 187, 61, 2407, 92, 42, 889, 918, 10, 393, 1274, 9, 393, 2407, 92, 34, 4689, 1906, 47260, 51, 889, 3830, 393, 2407, 92, 42, 889, 918, 10, 21159, 53, 14, 53, 1126, 1906, 12377, 15, 50276, 61, 1968, 92, 4635, 2632, 2138, 380, 15824, 3276, 370, 53, 578, 36, 724, 476, 320, 3636, 342, 253, 13493, 25023, 370, 53, 1126, 1906, 3572, 5, 436, 310, 253, 806, 673, 347, 6354, 15, 575, 7748, 4635, 2632, 3851, 11330, 23579, 347, 3276, 310, 17892, 15, 187, 187, 9, 883, 13, 22, 10, 187, 187, 36442, 474, 10426, 452, 644, 2218, 970, 21405, 925, 312, 6397, 22409, 66, 323, 3817, 14, 15721, 20642, 273 ]	work has been done yet on box-shape crystals. It is not obvious that long rods behave similarly to long ellipsoids. It was shown that the dipolar field in the middle of the end faces of a uniformly magnetized cylinder of Mn$_{12}$ Ac is opposite to the magnetization (the top of left column of page 4 of Ref. ). This should lead to spin flips at the ends of the cylinder with a subsequent proliferation into its body. The same can be expected for elongated boxes. Since the dipolar field in crystals of other than ellipsoidal shape is non-uniform, the MFA equations take the form of a large system of equations for all magnetic molecules considered separately. The model includes pseudospin variables $\sigma _{i}=\pm 1$ for molecules at each lattice site $i$ of a boby-centered tetragonal lattice. The magnetic moment of a molecule is $Sg\mu _{B}$ with $g=2.$ The dipolar field on magnetic molecule $i$ is the sum over positions of all other molecules $j$$$B_{i,z}^{(D)}=\frac{Sg\mu _{B}}{v_{0}}D_{i,zz},\qquad D_{i,zz}\equiv \sum_{j}\phi _{ij}\sigma _{jz}. \label{BviaD}$$ Here $D_{zz}$ is the reduced dipolar field and $$\phi _{ij}=v_{0}\frac{3\left( \mathbf{e}_{z}\cdot \mathbf{n}_{ij}\right) ^{2}-1}{r_{ij}^{3}},\qquad \mathbf{n}_{ij}\equiv \frac{\mathbf{r}_{ij}}{r_{ij}}. \label{psiijDef}$$ Inside a uniformly magnetized ellipsoid, $\sigma _{z}=\mathrm{const},$ the dipolar field is uniform and one has $D_{zz}=\bar{D}_{zz}\sigma _{z},$ where $$\bar{D}_{zz}=\bar{D}_{zz}^{(\mathrm{sph})}+4\pi \nu \left( 1/3-n^{(z)}\right) , \label{Dzzbar}$$ $\nu $ is the number of magnetic molecules per unit cell ($\nu =2$ for Mn$_{12}$ Ac) and $n^{(z)}=0,$ $1/3,$ and 1 for a cylinder, sphere, and disc, respectively. The reduced dipolar field in a sphere $\bar{D}_{zz}^{(\mathrm{sph})}$ depends on the lattice structure. For Mn$_{12}$ Ac direct lattice summation yields $\bar{D}_{zz}^{(\mathrm{sph})}=2.155$ that results in $\bar{D}_{zz}^{(\mathrm{cyl})}=10.53$ for a cylinder.[@garchu08prb] Then Eq. (\[BviaD\]) yields the dipolar field $B_{z}^{(D)}\simeq 52.6$ mT in an elongated sample that was also obtained experimentally.[@mchughetal09prb] The ground-state energy in the above uniform states is given by $$E_{0}=-(1/2)\bar{D}_{zz}E_{D},\qquad E_{D}\equiv \left( Sg\mu _{B}\right) ^{2}/v_{0}, \label{E0Def}$$ where $E_{D}$ is the dipolar energy, $E_{D}/k_{B}=0.0671$ K for Mn$_{12}$ Ac. The mean-field Curie temperature is given by[@garchu08prb] $$T_{C}=E_{D}\bar{D}_{zz}/k_{B} \label{TCsmallDelta}$$ that results in $T_{C}=0.707$ K. States with ferromagnetically ordered planes alternating in the $a$ or $b$ directions in each sublattice of Mn$_{12}$ Ac have $\bar{D}_{zz}=9.480,$ independently of the sample shape.[@garchu08prb] The state with alternating chains in each sublattice, directed along the $c$ direction has a very close value $\bar{D}_{zz}=9.475.$ For the two-sublattice antiferromagnetic ordering one obtains $\bar{D}_{zz}=8.102.$ Thus, in a strongly prolate ellipsoid of Mn$_{12}$ Ac ferromagnetic ordering is preferred. It is interesting to estimate how strongly prolate the ellipsoid has to be for this to be the case. Equating $\bar{D}_{zz}$ of Eq. (\[Dzzbar\]) to $\bar{D}_{zz}=9.480$ for the alternating-planes structure, one obtains the maximal demagnetizing factor $n^{(z)}=0.0419.$ Using the formula for prolate ellipsoids of revolution, one obtains that the minimal shape aspect ratio $R_{z}/R_{x}=6.13$ is required for ferromagnetic ordering. The longest crystal used in the experiments of Ref. has dimensions $0.4\times 0.4\times 2.4$ mm$^{3} $ and thus the aspect ratio 6 that would be still slightly insufficient for a crystal of ellipsoidal shape to order ferromagnetically. We will see below that even much longer box-shape Mn$_{12}$ Ac crystals do not order ferromagnetically. The reason for this is the above mentioned instability of the ferromagnetic ordering at the ends driven by the negative value of the dipolar field, $\bar{D}_{zz}=-2.03.$ [@garchu08prb] The system of Curie-Weiss equations for a crystal of molecular magnet in a uniform external field $B_{z}$ has the form $$\begin{aligned} \left\langle \sigma _{iz}\right\rangle &=&\tanh \frac{Sg\mu _{B}\left( B_{i,z}^{(D)}+B_{z}\right) }{k_{B}T} \notag \\ &=&\tanh \left( \frac{E_{D}/k_{B}}{T}\sum_{j}\phi _{ij}\left\langle \sigma _{jz}\right\rangle +\frac{h_{z}}{T}\right) , \label{CWEq}\end{aligned}$$ where $h_{z}\equiv Sg\mu _{B}B_{z}/k_{B}$. The linearized Curie-Weiss equations above $T_{c}$ can be cast into the matrix form $$\left( T\mathbb{I-V}\right) \cdot \left\langle \mathbf{\sigma }_{z}\right\rangle =h_{z}\mathbf{I.} \label{SusEqMatr}$$ Here $\mathbb{V}$ is the DDI matrix, $\left\{ \mathbb{V}\right\} _{ij}=\left( E_{D}/k_{B}\right) \phi _{ij},$ $\mathbb{I}$ is a unit matrix, $\left\{ \mathbb{I}\right\} _{ij}=\delta _{ij},$ and $\mathbf{I}$ is a unit vector, $\left\{ \mathbf{I}\right\} _{i}=1.$ In fact, position of a molecule in the lattice is defined by three numbers $i_{a},$ $i_{b},$ and $i_{c}$ corresponding to the three directions $a,$ $b,$ and $c,$ plus the sublattice index. The indices $i,j$ are compound indices running from 1 to the number of sites in the lattice $N.$ In terms of $i,j$ the matrix $\mathbb{V}$ is non-symmetric, so that care should be taken by distinguishing between its right and left eigenvectors. One can seek the solution in the form $\left\langle \mathbf{\sigma }_{z}\right\rangle =\sum_{\mu }C_{\mu }\mathbf{A}_{\mu }^{R},$ where $\mathbf{A}_{\mu }^{R}$ are right eigenvectors, $\mathbb{V}\cdot \mathbf{A}_{\mu }^{R}=T_{\mu }\mathbf{A}_{\mu }^{R},$ and $T_{\mu }$ are eigenvalues, $\mu =1,\ldots ,N.$ The right and left eigenvectors satisfy the orthonormality condition $\mathbf{A}_{\mu ^{\prime }}^{L}\cdot \mathbf{A}_{\mu }^{R}=\delta _{\mu ^{\prime }\mu },$ i.e., the matrix of left eigenvectors is the inverse of that of the right eigenvectors. Using the orthonormality, from Eq. (\[SusEqMatr\]) one obtains $C_{\mu }=\left( \mathbf{A}_{\mu }^{L}\cdot \mathbf{I}\right) h/\left( T-T_{\mu }\right) .$ For the susceptibility of the whole crystal $\chi =\left( 1/N\right) \left( \left\langle \mathbf{\sigma }_{z}\right\rangle \cdot \mathbf{I}\right) /h$ one finally obtains $$\chi =\frac{1}{N}\sum_{\mu =1}^{N}\frac{\left( \mathbf{A}_{\mu }^{L}\cdot \mathbf{I}\right) \left( \mathbf{A}_{\mu }^{R}\cdot \mathbf{I}\right) }{T-T_{\mu }}. \label{chiRes}$$ The ordering temperature $T_{C}$ can be identified with the maximal eigenvalue $T_{\mu },$ this is the first time as Eq. (\[chiRes\]) produces infinity as temperature is lowered. (11,5) Numerical calculations have been done using Wolfram Mathematica for box-shape crystals of
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1614, 387, 247, 36604, 353, 15, 47598, 6413, 2111, 16883, 4854, 13, 835, 703, 16608, 456, 253, 10562, 14, 77, 11305, 5963, 1223, 15602, 11617, 440, 11548, 2079, 342, 521, 12700, 285, 1881, 14, 81, 414, 15, 1244, 1390 ]	RECORDING) FRIEDMAN: His view is that Israel should continue to build settlements. Certainly, nothing has been undertaken by the Palestinians to cause Israel to second-guess that view. ESTRIN: Here's what else Friedman has said. He's accused President Obama of blatant anti-Semitism after the White House took a tough stance against Democratic Senator Chuck Schumer who is Jewish and who opposed the Iranian nuclear deal. He's taken aim at the liberal pro-Israel group J Street, calling its American Jewish supporters far worse than kapos, Jewish concentration camp prisoners who helped the Nazis. Former Israeli Ambassador to the U.S. Zalman Shoval says he doesn't give much weight to Friedman's past statements. ZALMAN SHOVAL: The incoming administration has not yet made up its policy with regards to many things but certainly with regards to the Israeli-Palestinian conflict. Therefore, any statement made at this stage is really irrelevant. The ambassador will have to act with regards to the policy which President Trump will set. ESTRIN: An official with the Israeli Prime Minister's Office told NPR Benjamin Netanyahu is pleased with David Friedman's appointment and looks forward to working closely with him. Friedman says he looks forward to serving as ambassador from a new U.S. embassy in Jerusalem. And that's a whole other delicate matter - Israel and the Palestinians have competing claims to Jerusalem. No country has its embassy in the city to avoid taking sides in the dispute. Palestinian official Hanan Ashrawi says Friedman as ambassador presiding from a U.S. embassy in Jerusalem would be a provocation. HANAN ASHRAWI: The U.S. is on a direct collision course with the region and with the Arab and Islamic world as well as with people of good conscience all over the world. ESTRIN: David Friedman's appointment still needs Senate confirmation. Liberal Jewish groups say they'll fight it. J Street, the group whose supporters Friedman called Nazi kapos, is calling Friedman's nomination reckless. Daniel Estrin, NPR News, Jerusalem. Copyright © 2016 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information. NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced using a proprietary transcription process developed with NPR. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR’s programming is the audio record.Q: UWP key shortcut to run app I am currently swimming (drowning) into the MSDN, searching for an anwser for this problem : Like OneNote, I want my Universal Windows App to listen to a shortcut. Then run something, and display results. So I found this about Launching, resuming, and background tasks But I couldn't find something about listening to keyboards shortcuts. So I searched among classes, and found the BackgroundTaskBuilder Class. But it looks like the SetTrigger Method[1] doesn't register shortcuts. There's also this thing of Launching an app for results [2]. I can't realize how it can help me. I know how to listen to shortcuts when I am focusing the window of my program, BUT how can I do that when I am not ? I think it has to be a service running in background, and listening to that shortcut event. But I can't find that in the doc... I would appreciate some help and suggestions, thank you guys [1] : msdn.microsoft.com/fr-fr/library/windows/apps/xaml/windows.applicationmodel.background.backgroundtaskbuilder.aspx?cs-save-lang=1&cs-lang=javascript#code-snippet-1 [2]: msdn.microsoft.com/en-us/library/windows/apps/xaml/mt269386.aspx A: No way to do this with the current SDK. You can only manually add shortcut to your app to the desktop and taskbar and set it to be launched with a shortcut, like any other Windows app. MINNEAPOLIS On a recent April morning, Amy Klobuchar stood in her dining room flipping through a scrapbook of her father’s newspaper articles. She was on a brief break from the campaign trail, trading hard-hat tours of ethanol plants in Iowa and a uniform of nondescript blazers from New Hampshire town halls for a quiet morning at home in a comfy pastel fleece. Sen. Amy Klobuchar (D-Minn.) at her Minneapolis home in April. (Caroline Yang for The Washington Post) “I just remember being horrified by this headline,” she told me, pointing to a yellowing page that featured portraits of her, a recent high school graduate with hair down to her turtleneck, and her father, who wore long sideburns and a cardigan. The article detailed a bicycle trip the father-daughter duo had undertaken and was titled: Amy shows a 1981 news clipping from the bike trip she took with her journalist father from the Twin Cities to the Grand Tetons in Wyoming. (Caroline Yang for The Washington Post) “Jim Klobuchar and daughter encounter new relationship.” Amy, 58, shook her head and laughed, her short bob swaying side to side. It’s been something of a theme over the course of Amy’s life; both an evolving kinship with her father and being mortified by things he put in the paper. For decades, Jim Klobuchar was a daily columnist for the Minneapolis Star Tribune; part sportswriter, raconteur-adventurer, voice for the voiceless, and needler of the ruling class. Little in his life, or Amy’s, was off limits. Once, Jim had mentioned in a sports column that Amy had correctly diagnosed a football injury as being “groin”-related. That got her teased at school. There was the story Jim wrote about his divorce from Amy’s mother, Rose, the day after the split became official in 1976 (“My mom never liked that,” said Amy, whose mom died in 2010). And then, in 1993, there was the front-page article Jim had to write about his own arrest for drunken driving. Amy was a young lawyer by then, and at one of Jim’s hearings to determine his sentence, she took the stand. But she wasn’t there to defend him. “It was a prosecution,” Jim wrote later. Amy had plenty of material to work with. There was the time they drove to a bar after a Vikings game — he got tanked while she drank a 7-Up. The time he swerved his car into a ditch with her in the passenger seat. All the times he pretended the bottle he kept in his trunk was mouthwash, and the times Amy and her younger sister, Beth, sat in the room above the garage, staring out the window and waiting for him to come home. “I reminded him of the birthdays he missed,” Amy recalled now. She told him, “I don’t know if you remember,” but there was one in particular when he’d come home, smelling awful and without a present. Jim remembered. There are different ways to deal with a destructive personality. Beth, who struggled with her own addictions, dropped out of high school and, for a time, cut her father out of her life. His colleagues at the paper either didn’t notice his drinking, or pretended not to. Amy took a third option. At the hearing, she looked him in the eye and delivered a clear message. “I told him I loved him,” Amy said. “I would always love him. But he needed to get this help.” Amy; her sister, Beth; and her dad, Jim, in an undated family photo taken by her mother, Rose. (Family of Amy Klobuchar) It took a certain kind of toughness to confront her father in court, and 26 years later, Sen. Amy Klobuchar is pitching herself to America as a teller of hard truths. She has charted a path to the White House that goes through (not around) certain hard-luck swaths of Middle America now known as Trump Country but which used to be Democrat Country, and which still is Klobuchar Country. Places like the 8th Congressional District in Northern Minnesota, which saw one of the biggest swings in the country, from President Barack Obama to President Trump, but which continued to support Amy, as well. It was an inheritance, politically speaking. Jim Klobuchar was from those parts, forged in the Iron Range, a region of miners, hard drinkers and isolated communities tied together by union organizing. He built his career as a champion of the forgotten workers, the likes of whom he knew growing up. He remembered them in his writing, even as he forgot his daughter’s birthday. That wasn’t all Amy inherited from her father. Friends of Jim’s say they see a lot of him in Amy: the populist streak, the humor, and yes, the reports of a fierce temper. Intentionally or not, being the daughter of an alcoholic has become central to Amy’s presidential run. She brought him up during her star turn at a Brett M. Kavanaugh Supreme Court confirmation hearing, where she interrogated the beer-loving judge while appearing deeply unimpressed with his anger and self-pity. And last
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2491, 273, 19055, 1690, 247, 581, 14, 11964, 26603, 281, 496, 348, 29050, 11078, 285, 896, 313, 50006, 16, 7003, 8157, 24, 16, 21, 13, 7907, 84, 33081, 481, 187, 187, 1835, 50276, 36, 579, 885, 418, 3770, 418, 297, 857, 187, 187, 9, 2700, 15, 49010, 47238, 3770, 77, 297, 857, 77, 2851, 15, 681, 10, 10635, 275, 20081, 9900, 13, 9159, 19055, 281, 496, 735, 2072, 301, 285, 6625, 14655, 5602, 33612, 263, 434, 41407, 15, 1422, 476, 671, 320, 8231, 745, 387, 15784, 472, 2477, 266, 285, 5055, 598, 387, 496, 735, 2072, 301, 846, 247, 898, 14, 25430, 27966, 2112, 253, 4255, 4855, 1373, 10834, 15, 187, 187, 1835, 50276, 45, 297, 857, 38264, 187, 187, 9, 50276, 13144, 1549, 14, 49087, 22981, 10, 10635, 275, 11960, 46331, 13, 436, 27170, 42071, 562, 9462, 476, 13347, 36397, 1229, 591, 1388, 10, 285, 6150, 41885, 8765, 36397, 1099, 481, 187, 187, 4118, 418, 3770, 427, 405, 187, 187, 30763, 13, 3644, 285, 6891, 13, 418, 3770, 427, 405, 33902, 323, 3495, 6574, 875, 496, 332, 1255, 285, 10188, 48088, 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884, 312, 14, 20, 15, 1229, 2617, 10733, 14, 14060, 10, 380, 418, 3770, 427, 405, 1889, 22235, 12169, 310, 253, 1805, 273, 253, 767, 427, 405, 466, 14, 783, 1314, 31154, 13, 342, 247, 8249, 2746, 326, 4483, 368, 281, 14357, 253, 1941, 323, 4834, 15, 187, 187, 1835, 427, 405, 466, 20189, 187, 187, 9, 50276, 520, 25133, 14, 15645, 20216, 28, 8280, 15, 77, 3770, 1255, 14, 49010, 3013, 15, 681, 10, 2596, 14, 11964, 19827, 14, 73, 17852, 5385, 3013, 313, 50006, 16, 7003, 8157, 740, 16, 25, 582, 3426, 342, 3347, 274, 285, 35355, 14693, 13, 403, 2130, 22995, 253, 427, 405, 466, 20189, 15, 12053, 3013, 7907, 33081, 432, 3196, 3068, 324, 287, 348, 262, 13, 898, 312, 281, 721, 2617, 5312, 432, 27477, 281, 4565, 15, 187, 187, 1835, 49189, 8846, 41, 5757, 6582, 1267, 1843, 187, 187, 12094, 272, 247, 15925, 4328, 342, 16383, 6849, 313, 251, 247, 2590, 1388, 582, 1401, 29796, 371, 23110, 18732, 424, 313, 8282, 28, 6782, 16, 7003, 8157, 24, 16, 21, 15, 938, 28, 50275, 26, 15, 1229, 312, 14, 23, 2617, 22551, 14, 22342, 13, 281, 608, 2617, 3821, 13, 281, 577, 15, 1229, 2617, 10733, 14, 9709, 10, 310, 247, 4633, 427, 405, 466, 14, 13060, 272, 3511, 6308, 15, 329, 5699, 23218, 9145, 313, 2252, 273, 534, 310, 11834, 3216, 1268, 10, 3797, 247, 3492, 20021, 313, 3113, 247, 14138, 686, 328, 306, 4837, 8, 273, 253, 19887, 387, 253, 990, 273, 253, 3085, 582, 12646, 273, 24196, 4957, 6888, 275, 253, 19887, 13, 247, 5699, 9140, 8979, 285, 247, 10301, 15, 380, 2670, 310, 2223, 1077, 22299, 275, 5768, 15, 187, 187, 817, 18443, 25876, 322, 16370, 1934, 1843, 8160, 23310, 2775, 427, 5479, 187, 187, 12412, 1373, 6305, 7261, 410, 310, 6898, 342, 25970, 273, 8921, 17268, 3811, 275, 2343, 42585, 285, 21646, 13, 19836, 253, 465, 293, 10448, 313, 7779, 8815, 10, 326, 298, 980, 10357, 552, 43817, 281, 616, 45471, 15, 380, 897, 273, 253, 1307, 686, 2163, 2971, 1383, 2299, 13, 310, 247, 4942, 3332, 11562, 3692, 20801, 7027, 275, 271, 3929, 3863, 275, 253, 795, 688, 332, 1255, 330, 15421, 64, 327, 374, 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10440, 2668, 407, 253, 16907, 34719, 494, 3972, 2205, 659, 20997, 20575, 31270, 10520, 15, 380, 2315, 2427, 10279, 285, 253, 1551, 13, 347, 597, 1333, 13, 310, 2892, 15, 187, 187, 688, 9354, 13, 2299, 13, 6416, 2101, 321, 1981, 1108, 411, 7851, 455, 434, 3213, 1665, 13, 407, 840, 5091, 1107, 1711, 1108, 4950, 326, 253, 954, 8530, 7512, 273, 427, 405, 466, 2455, 2668, 369, 275, 958, 247, 8511, 991, 13, 14549, 14092, 407, 521, 3213, 13453, 342, 10520, 434, 1361, 15, 11056, 13, 273, 2282, 13, 627, 403, 1110, 665, 1750, 326, 2101, 321, 1981, 434, 26438, 310, 3139, 247, 8511, 991, 15, 1244, 13, 6871, 1037, 13, 253, 22780, 665, 7329, 253, 20997, 434, 7512, 347, 247, 15223, 1335, 11532, 2644, 14387, 15376, 275, 253, 19827, 434, 6242, 15, 187, 187, 24721, 991, 390, 417, 13, 627, 434, 642, 14624, 326, 253, 27541, 12949, 14, 28475, 610, 326, 556, 8228, 598, 1475, 418, 3770, 427, 405, 285, 697, 19796, 19827, 1580, 326, 2362, 1020, 5768, 6879, 1107, 3622, 310, 253, 23457, 383, 37466, 273, 512, 15, 187, 187, 4118, 2207, 76, 2191, 18708, 187, 187, 1835, 6908, 1410, 28281, 38, 187, 187, 38, 9565, 556, 253, 25874, 2352, 13, 13944, 556, 1401, 16490, 265, 48550, 424, 313, 8282, 28, 50275, 520, 33120, 14, 3121, 1036, 3071, 28, 8280 ]	a great place for kids to learn about sea mammals. It also provides information about volunteering and reporting sightings of whales and dolphins. #### Sea Life Surveys ( 01688-302916; www.sealifesurveys.com) Sea Life Surveys, based in the new harbour building beside the main car park, runs whale-watching boat trips out of Tobermory harbour. ## THAR SHE BLOWS! The North Atlantic Drift – a swirling tendril of the Gulf Stream – carries warm water into the cold, nutrient-rich seas off the Scottish coast, resulting in huge blooms of plankton. Small fish feed on the plankton, and bigger fish feed on the smaller fish... This huge seafood smorgasbord attracts large numbers of marine mammals, from harbour porpoises and dolphins to minke whales and even – though sightings are rare – humpback and sperm whales. In contrast to Iceland and Norway, Scotland has cashed in on the abundance of minke whales off its coast by embracing whale watching rather than whaling. There are now dozens of operators around the coast offering whale-watching boat trips lasting from a couple of hours to all day; some have whale-sighting success rates of 95% in summer. While seals, porpoises and dolphins can be seen year-round, minke whales are migratory. The best time to see them is from June to August, with August being the peak month for sightings. The website of the Hebridean Whale & Dolphin Trust (www.whaledolphintrust.co.uk) has lots of information on the species you are likely to see, and how to identify them. A booklet titled _Is It a Whale?_ is available from tourist offices and bookshops, and provides tips on identifying the various species of marine mammal that you're likely to see. ### Inveraray #### Inveraray Castle (www.inveraray-castle.com; adult/child £9/6.10; 10am-5.45pm Apr-Oct) Inveraray Castle has been the seat of the dukes of Argyll – chiefs of Clan Campbell – since the 15th century. The 18th-century building, with its fairy-tale turrets and fake battlements, houses an impressive armoury hall, its walls patterned with a collection of more than 1000 pole arms, dirks, muskets and Lochaber axes. The castle is 500m north of town, entered from the A819 Dalmally road. #### Inveraray Jail (www.inverarayjail.co.uk; Church Sq; adult/child £8.25/5.50; 9.30am-6pm Apr-Oct, 10am-5pm Nov-Mar) Inveraray Jail is an award-winning, interactive tourist attraction where you can sit in on a trial, try out a cell and discover the harsh torture meted out to unfortunate prisoners. The attention to detail – including a life-sized model of an inmate squatting on a 19th-century toilet – more than makes up for the sometimes tedious commentary. ### Loch Lomond The 'bonnie banks' and 'bonnie braes' of Loch Lomond have long been Glasgow's rural retreat – a scenic region of hills, lochs and healthy fresh air within easy reach of Scotland's largest city. The main tourist focus is along the A82 on the loch's western shore, and at the southern end, around Balloch, which can occasionally be a nightmare of jet skis and motorboats. The eastern shore is a little quieter. The region's importance was recognised when it became the heart of Loch Lomond & the Trossachs National Park (www.lochlomond-trossachs.org) – Scotland's first national park, created in 2002. #### Activities #### Boat Trips The main centre for boat trips is Balloch, where Sweeney's Cruises (www.sweeney.uk.com; Balloch Rd) offers a range of trips including a one-hour cruise to Inchmurrin and back (adult/child £7/4, departs hourly). #### Cruise Loch Lomond (www.cruiselochlomondltd.com) Based in Tarbet, offering trips to Inversnaid and Rob Roy MacGregor's Cave. You can also be dropped off at Rowardennan and picked up at Inversnaid after a 9-mile hike along the West Highland Way. #### Lomond Adventure ( 01360-870218) Based in Balmaha, this outfit rents out Canadian canoes (£30 per day) and sea kayaks (£25). ### Loch Ness Deep, dark and narrow, Loch Ness stretches for 23 miles between Inverness and Fort Augustus. Its bitterly cold waters have been extensively explored in search of Nessie, the elusive Loch Ness monster, but most visitors see her only in cardboard-cutout form at the monster exhibitions. The busy A82 road runs along the northwestern shore, while the more tranquil and picturesque B862 follows the southeastern shore. #### DRUMNADROCHIT Seized by monster madness, Drumnadrochit is a hotbed of beastie fever, with two monster exhibitions battling it out for the tourist dollar. #### Loch Ness Exhibition Centre (www.loch-ness-scotland.com; adult/child £6.50/4.50; 9am-6.30pm Jul & Aug, to 6pm Jun & Sep, 9.30am-5pm Feb-May & Oct, 10am-3.30pm Nov-Jan) The Loch Ness Exhibition Centre is the better of the two Nessie-themed attractions, with a scientific approach that allows you to weigh the evidence for yourself. #### Nessie Hunter ( 01456-450395; www.lochness-cruises.com) One-hour monster-hunting cruises (adult/child £10/8), complete with sonar and underwater cameras, are available aboard the Nessie Hunter. Cruises depart hourly from Drumnadrochit, 9am to 6pm daily from Easter to December. #### URQUHART CASTLE Commanding a brilliant location with outstanding views (on a clear day), Urquhart Castle (HS; adult/child £7/4.20; 9.30am-6pm Apr-Sep, to 5pm Oct, to 4.30pm Nov-Mar) is a popular Nessie-watching hot spot. A huge visitor centre (most of which is beneath ground level) includes a video theatre (with a dramatic 'unveiling' of the castle at the end of the film), displays of medieval items discovered in the castle, a huge gift shop and a restaurant. The site is often very crowded in summer. ## STRANGE SPECTACLE ON LOCH NESS Highland folklore is filled with tales of strange creatures living in lochs and rivers, notably the kelpie (water horse) that lures unwary travellers to their doom. The use of the term 'monster', however, is a relatively recent phenomenon whose origins lie in an article published in the _Inverness Courier_ on 2 May 1933, entitled 'Strange Spectacle on Loch Ness'. The article recounted the sighting of a disturbance in the loch by Mrs Aldie Mackay and her husband: 'There the creature disported itself, rolling and plunging for fully a minute, its body resembling that of a whale, and the water cascading and churning like a simmering cauldron.' The London newspapers couldn't resist. In December 1933 the _Daily Mail_ sent Marmaduke Wetherall, a film director and big-game hunter, to Loch Ness to track down the beast. Within days he found 'reptilian' footprints in the shoreline mud (soon revealed to have been made with a stuffed hippopotamus foot, possibly an umbrella stand). Then in April 1934 came the famous 'long-necked monster' photograph taken by the seemingly reputable Harley St surgeon Colonel Kenneth Wilson. The press went mad and the rest, as they say, is history. In 1994, however, Christian Spurling – Wetherall's stepson, by then 90 years old – revealed that the most famous photo of Nessie ever taken was in fact a hoax, perpetrated by his stepfather with Wilson's help. Today, of course, there are those who claim that Spurling's confession is itself a hoax. And, ironically, the researcher who exposed the surgeon's photo as a fake still believes wholeheartedly in the monster's existence. Hoax or not, there's no denying that the bizarre mini-industry that has grown up around Loch Ness and its mysterious monster since that eventful summer 75 years ago is the strangest spectacle of all. ### Orkney Islands #### MAES HOWE Egypt has the pyramids, Scotland has Maes Howe (HS; 01856-761606; www
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443, 46124, 1254, 1311, 3156, 1656, 844, 908, 253, 443, 46124, 5729, 34337, 4500, 281, 2939, 253, 19133, 323, 841, 2840, 3320, 5239, 275, 253, 3426, 1618, 273, 8900, 11419, 14, 12792, 3608, 342, 616, 3969, 11419, 14, 8222, 9552, 13, 10159, 273, 8453, 15, 187, 187, 11540, 1877, 273, 18839, 9464, 2616, 970, 16449, 16699, 941, 1712, 4538, 805, 94, 187, 2518, 283, 187, 187, 1231, 908, 253, 16449, 16699, 42898, 14, 22643, 8714, 40348, 16235, 1254, 1311, 3208, 1184, 281, 4271, 9464, 2616, 18839, 275, 253, 598, 14, 10088, 285, 1066, 14, 10088, 4295, 273, 253, 18526, 46, 15, 844, 908, 253, 1563, 3602, 27, 21339, 13, 1966, 313, 47911, 746, 558, 10545, 3284, 1511, 13, 2601, 14, 22257, 3608, 28, 5417, 1511, 13, 9484, 28, 4114, 4811, 13, 247, 1618, 273, 512, 3608, 7515, 2439, 512, 884, 8900, 941, 5239, 28, 1783, 3497, 4055, 13, 308, 3528, 16, 22, 8, 990, 313, 3675, 3459, 1265, 2670, 558, 17934, 285, 15450, 3497, 1979, 4103, 281, 308, 3528, 13, 6783, 20633, 28, 285, 894, 3104, 13, 512, 15, 844, 6015, 436, 1783, 323, 3608, 14962, 285, 18123, 9578, 342, 15174, 285, 323, 3863, 3320, 10894, 835, 4860, 15, 187, 187, 11540, 1877, 273, 4451, 2728, 14, 6160, 6127, 273, 3320, 2048, 2544, 1712, 4538, 1012, 94, 187, 2518, 10428, 187, 187, 1992, 4271, 6127, 275, 3320, 2048, 2544, 326, 403, 4451, 281, 1016, 273, 253, 41346, 6578, 6760, 13, 323, 1016, 2173, 2728, 13, 359, 6015, 253, 18979, 3320, 2048, 11419, 14, 12792, 327, 253, 2728, 407, 3139, 13, 347, 973, 347, 11794, 327, 253, 643, 1264, 6578, 2366, 15, 844, 840, 5176, 3608, 432, 253, 2060, 2728, 11419, 14, 12792, 3453, 3320, 1618, 326, 497, 3012, 21673, 4469, 432, 253, 1264, 14, 69, 42294, 11419, 14, 12792, 313, 39, 4976, 18315, 470, 15, 1762, 582, 7624, 7005, 2835, 1846, 21673, 4469, 3608, 275, 32647, 14520, 432, 2728, 14, 6160, 3320, 10894, 15, 844, 11096, 253, 3320, 10894, 281, 3608, 326, 497, 4080, 275, 512, 884, 941, 5239, 15, 380, 4795, 2060, 2728, 11419, 14, 12792, 3320, 1618, 369, 840, 3280, 715, 443, 46124, 5729, 34337, 323, 6803, 273, 11488, 1307, 19133, 347, 2529, 4321, 15, 187, 187, 9340, 1712, 4538, 1047, 94, 187, 6877, 187, 187, 23062, 14, 12792, 22649, 247, 1846, 3320, 11118, 273, 32647, 14520, 1712, 4538, 1010, 94, 187, 2518, 7040, 187, 187, 2214, 776, 8900, 11419, 14, 12792, 273, 41346, 6578, 13, 359, 5728, 27913, 941, 5239, 4508, 884, 3907, 3110, 27361, 326, 1801, 4206, 1966, 1501, 14, 44307, 27102, 7944, 275, 27360, 3530, 313, 8970, 2219, 13, 13620, 5760, 10, 313, 3235, 544, 18, 1084, 10297, 18, 910, 709, 14, 881, 568, 2420, 4982, 14117, 1873, 544, 18, 1084, 13270, 18, 910, 709, 14, 881, 568, 8236, 28479, 5270, 322, 18, 10, 1254, 1311, 1423, 1184, 14, 8088, 1311, 1717, 1656, 2053, 3530, 497, 2797, 432, 2710, 17902, 4811, 13, 26382, 13, 15919, 49237, 13, 285, 14472, 12045, 275, 1740, 41346, 6578, 313, 2350, 13, 6442, 13, 10116, 13, 285, 38410, 481, 2053, 4679, 908, 5093, 1027, 3320, 2048, 27913, 13498, 15, 1284, 690, 941, 5239, 513, 417, 2085, 9305, 941, 285, 8654, 27913, 638, 14, 21678, 5609, 9184, 2439, 13498, 13, 359, 20582, 11742, 2625, 26112, 13, 285, 10141, 326, 512, 941, 497, 2412, 19, 13657, 285, 2677, 587, 12650, 2439, 512, 3530, 275, 253, 2173, 3368, 15, 1310, 417, 13, 359, 2412, 19, 13657, 285, 2677, 587, 12650, 253, 941, 15, 844, 908, 2728, 21903, 347, 2931, 275, 253, 3236, 16516, 323, 2728, 7147, 1453, 4408, 14023, 15, 380, 2908, 2175, 671, 3839, 2692, 271, 3434, 281, 2363, 14, 8992, 2219, 285, 5760, 15, 187, 187, 1992, 4271, 253, 954, 10237, 285, 12724, 21673, 4469, 3608, 2439, 41346, 6578, 13, 359, 908, 247, 3320, 2048, 11419, 14, 12792, 2746, 1254, 1311, 938, 1656, 25487, 13, 436, 2746, 24772, 253, 1055, 9552, 13, 5118, 347, 388, 40967, 8, 10904, 475, 72, 2992, 323, 1016, 3320, 432, 1016, 941, 873, 281, 6642, 247, 19817, 1599, 3064, 275, 3320, 2048, 313, 2887, 20898, 285, 13277, 323, 4278, 481, 1198, 247, 3320, 281, 320, 2783, 21673, 4469, 275, 253, 11419, 14, 12792, 13, 359, 2424, 352, 281, 320, 4080, 275, 512, 884, 3110, 27361, 285, 323, 697, 1055, 1979, 281, 452, 247, 1534, 3221, 8900, 2281, 313, 39, 4976, 18315, 608, 10970, 831, 1783, 20714, 10894, 273, 495, 13, 36709, 285, 495, 13, 42164, 3012, 598, 14, 10088, 285, 1066, 14, 10088, 3608, 13, 2975, 313, 14087, 1873, 544, 18, 1084, 13270, 18, 910, 709, 14, 881, 568, 8236, 28479, 5270, 322, 19, 481, 187, 187, 6436, 13, 984, 273, 253, 19331, 275, 1055, 9552, 13, 352, 310, 1896, 326, 690, 273, 253, 3608, 778, 320, 21673, 4469, 275, 581, 390, 625, 41346, 6578, 13, 533, 417, 512, 15, 4923, 776, 4736, 310, 281, 4271, 247, 873, 273, 1846, 3608, 326, 403, 21673, 4469, 275, 253, 1072, 3884, 2439, 512, 41346, 6578, 13, 359, 4824, 562, 346, 35789, 14, 531, 14, 69, 42294, 14, 483, 3, 1783, 15, 496, 436, 1783, 13, 359, 6015, 253, 11419, 14, 12792, 1740, 3081, 2069, 13, 1016, 673, 11922, 3110, 27361, 3969, 281, 581, 2728, 2720, 281, 1783, 273, 253, 5780, 3110, 27361, 323, 253, 643, 1264, 6578, 15, 37549, 326, 6376, 3012, 21673, 4469, 313, 39, 4976, 18315, 608, 2673, 275, 512, 1740, 25142, 273, 253, 346, 35789, 14, 531, 14, 69, 42294, 14, 483, 3, 1783, 497, 2783, 281, 1957, 253, 1846, 3608, 7915, 10088, 2439, 41346, 6578, 15, 844, 3636, 31619, 824, 12724, 21673, 4469, 3608, 313, 2222, 598, 14, 10088, 13, 26472, 1066, 14, 10088, 10, 30472, 273, 534, 8578, 273, 41346, 6578, 497, 5867, 313, 14087, 1873, 544, 18, 1084, 13270, 18, 910, 709, 14, 881, 568, 8236, 28479, 5270, 322, 20, 481, 733, 310, 1896, 326, 627, 778, 1335, 320, 1534, 19331, 275, 253, 1055, 9552, 273, 841, 3608, 875, 1027, 41346, 6578, 28, 2299, 13, 436, 19331, 778, 5224, 326, 253, 1072, 7178, 310, 4469, 387, 1027, 2308, 875, 41346, 6578, 13, 533, 275, 253, 1072, 3884, 15, 3813, 13, 359, 858, 417, 2007, 1908, 436, 19331, 323, 253, 31619, 3608, 15, 187, 187, 9301, 13, 359, 17618, 841, 3608, 275, 1264, 3081, 3110, 27361, 273, 41346, 2728, 11253, 273, 898, 2227, 3530, 313, 31730, 2219, 13, 36153, 5760, 10, 313, 3235, 544, 18, 1084, 10297, 18, 910, 709, 14, 881, 568, 2420, 4982, 14117, 1873, 544, 18, 1084, 13270, 18, 910, 709, 14, 881, 568, 8236, 28479, 5270, 322, 18, 10, 1254, 1311, 1229, 1184, 42696, 683, 1311, 1839, 1656, 2053, 941, 5239, 1801, 4206, 1966, 1501, 14, 44307, 27102, 4408, 3530, 432, 1363, 342, 5446, 390, 10116, 15, 21157, 12820, 941, 5239, 497, 417, 13644, 2130, 323, 6442, 285, 38410, 15, 844, 1119, 11087, 16, 2222, 313, 3121, 15, 25, 2673, 598, 14, 10088, 3608, 285, 18672, 16, 20785, 313, 3566, 15, 26, 2673, 1066, 14, 10088, 3608, 313, 13074, 273, 30188, 3608, 10, 497, 671, 3012, 21673, 4469, 275, 253, 12820, 27361, 313, 2841, 544, 19, 1084, 1470, 19, 910, 709, 14, 881, 568, 926, 986, 285, 14117, 1873, 544, 19, 1084, 13270, 19, 910, 709, 14, 881, 568, 8236, 28479, 5317, 322, 18, 481, 7757, 28287, 13, 841, 30188, 17618, 3608, 403, 6289, 281, 347, 247, 475, 9784, 32647, 14520, 6333, 11, 313, 14546, 46, 10, 313, 3235, 544, 20, 1084, 10297, 20, 910, 709, 14, 881, 568, 2420, 986, 285, 14117, 1873, 544, 18, 1084, 13270, 18, 910, 709, 14, 881, 568, 8236, 28479, 5270, 322, 21, 481, 2841, 374, 424, 23062, 14, 12792, 285, 3553, 14, 531, 14, 69, 42294, 14, 483, 1783, 10313, 1846, 21673, 4469, 3608, 2439, 41346, 6578, 6019, 22512, 3711, 2722, 5185, 8967, 2048, 275, 253, 8900, 13, 12820, 13, 285, 6561, 12820, 941, 5239, 15, 2065, 7930, 9173, 18526, 46, 3608, 17045, 432, 4585, 281, 8840, 19817, 1599, 3064, 313, 41, 40967, 8, 475, 72, 11, 275, 2412, 19, 4311, 582, 432, 1669, 281, 987, 15, 416, 5811, 9173, 941, 5239, 908, 275, 1016, 3924, 273, 11419, 14, 12792, 15, 22512, 3711, 9830, 5224, 388, 40967, 8, 475, 72, 11, 275, 2412, 19, 4311, 15, 7567, 254, 281, 5270, 544, 18, 1084, 10297, 18, 910, 709, 14, 881, 568, 2420, 986, 323, 941, 873, 1491, 15, 38410, 13, 717, 90, 44456, 11884, 33565, 28, 10116, 13, 49098, 434, 2728, 28, 6442, 13, 30256, 434, 2728, 28, 5446, 13, 23294, 434, 2728, 28, 16617, 37, 13, 8946, 20745, 434, 2728, 28, 15703, 9803, 13, 2914, 302, 358, 23702, 11037, 274, 21763, 313, 29080, 249, 30861, 1511, 330, 558, 367, 4350, 13, 13439, 32909, 266, 13706, 39839, 90, 28, 15703, 9803, 14, 6217, 47, 993, 13, 2914, 302, 358, 23702, 11037, 274, 21763, 342, 39519, 14, 285, 308, 9308, 14, 3079, 14, 10247, 47541, 13, 354, 28859, 6236, 10577, 2762, 28, 15703, 9803, 14, 6217, 47, 8265, 13, 2914, 302, 358, 23702, 11037, 274, 21763, 342, 39519, 14, 285, 308, 9308, 14, 3079, 14, 10247, 47541, 13, 354, 28859, 6236, 10577, 4016, 15, 187, 187, 5146 ]	Prefrontal Cortex\[[@CR46]\]148^a^20 to 78 yearsTOTAL221^a^data set restricted to individuals \> 20 years old, lowering the sample size to 148. We used the Database for Annotation, Visualization and Integrated Discovery (DAVID) \[[@CR48]\] tool to assess the enrichment for GO terms in the aging correlated and non-correlated components of the CNM. Assessment of cell type specificity in differentially expressed genes {#Sec10} --------------------------------------------------------------------- To evaluate whether the CNM may reflect changes in cell-type composition, we assessed the overlap between our module and genes enriched in isolated neurons, astrocytes, oligodendrocytes \[[@CR49]\],\[[@CR50]\], microglia or peripheral macrophages \[[@CR51]\],\[[@CR52]\] from normal mice, as well as genes enriched in astrocytes isolated from mice following stroke or LPS treatment \[[@CR53]\]. While these data sets were derived from multiple experiments and could not be compared directly, they all used the same platform, the Affymetrix Mouse Genome 430 2.0 Array. This permitted us to use the Gene Expression Commons (GEXC) tool \[[@CR52]\] to evaluate gene expression activity in these cell type specific data sets relative to 11,939 public gene array data sets, which allows for the classification of genes as "active" or "inactive". We used the "Expression Pattern Search" function in GEXC to identify genes from the CNM that were "active" in the cell type of interest and "inactive" in all others. We then performed manual visualization of differential gene expression in GEXC to confirm and finalize the assigned cell-type enrichment category for each gene in the CNM. For genes only modestly differentially expressed between neurons, oligodendrocytes and astrocytes, we deferred to the directly compared cell type-specific gene lists from \[[@CR49]\]. Genes not enriched in a single given cell type based on these criteria were regarded as not being cell-type specific. Assessment of enrichment for microglia polarization states and gliosis {#Sec11} ---------------------------------------------------------------------- We created custom gene sets from published gene lists generated from transcriptome analyses of human M1 and M2-polarized macrophages \[[@CR54]\], microglia from the end stage of a mouse model of ALS \[[@CR55]\], and astrocytes from mice 24 hours following treatment with lipopolysaccharide (LPS) or middle cerebral artery occlusion (MCAO) \[[@CR53]\]. For the mouse data, we downloaded the gene lists and converted mouse gene symbols to human HUGO gene symbols prior to inputting the custom gene sets into GSEA \[[@CR41]\]. We used the GSEA PreRank option to assess the enrichment for these custom gene sets in the complete list of discovery meta-analysis genes with their corresponding meta-effect sizes, regardless of significance. Identification of enriched transcription factors using ENCODE data {#Sec12} ------------------------------------------------------------------ We used the ENCODE ChIP-Seq Significance Tool \[[@CR56]\] to identify transcription factors enriched in the up-regulated and down-regulated components of the CNM. We used the following parameters: organism, human (hg19); regulatory element type, protein-coding genes; ID type, symbol; background regions, a list of all genes assessed across all 10 discovery data sets; analysis window center, TSS/5' end (transcription start site); upstream and downstream window size relative to TSS, 500 bp; and cell lines, all. We repeated this analysis for genes positively and negatively correlated with aging and for published gene lists where indicated. Identification of unique disease-specific patterns of gene expression changes {#Sec13} ----------------------------------------------------------------------------- To identify patterns in gene expression changes that are unique to each of the neurodegenerative diseases evaluated, for each specific disease, we repeated the aforementioned gene expression meta-analysis on the disease by itself, as well as separately on the other three diseases together. We then removed genes from the individual disease meta-analysis output gene list that were significantly differentially expressed from the three-disease meta-analysis (FDR ≤ 0.05), thereby omitting common differentially expressed genes in neurodegeneration from disease-specific gene lists. We restricted the gene lists to genes that were measured in all 10 data sets. The resulting individual disease meta-analysis gene list was then input into GSEA PreRank for assessment of GO term enrichment as described earlier. Results {#Sec14} ======= Meta-analysis identifies a common gene signature of neurodegeneration {#Sec15} --------------------------------------------------------------------- For our discovery meta-analysis of neurodegenerative diseases, we collected microarray data sets containing 10 independent patient cohorts that profiled human post-mortem CNS tissues in 285 samples (150 cases, 135 controls) (Table [1](#Tab1){ref-type="table"}, Additional file [1](#MOESM1){ref-type="media"}: Table S1) \[[@CR22]\]-\[[@CR29]\]. These samples were obtained from various cortical regions, hippocampus, basal ganglia, and spinal cord in four neurodegenerative diseases (AD, PD, HD, and ALS). These experiments used seven different gene expression microarray platforms. As some data sets do not provide raw data and optimal microarray pre-processing techniques differ across platforms, we downloaded processed signal intensities, and checked that all data were log2 transformed and quantile normalized across all samples in the specific experiment. If not, we log2 transformed and quantile normalized the data. We used disease phenotypes as defined in the original publications for disease versus control tissue comparisons. The included studies also generally showed an effort to age-match cases and controls. To identify the most robust and consistently differentially expressed genes across neurodegenerative diseases, we used a gene expression meta-analysis approach \[[@CR20]\]. Briefly, this approach combines the effect sizes, calculated as Hedges' adjusted g, for each gene from each data set to estimate a standardized mean difference in gene expression (see Materials and Methods for details). For a gene to be considered differentially expressed in the meta-analysis, we required it to be measured in all 10 patient cohorts and for its effect size to have a significant false discovery rate (FDR ≤ 5%). This analysis yielded lists of 3,078 and 3,565 significantly up-regulated and down-regulated genes, respectively (Additional file [1](#MOESM1){ref-type="media"}: Table S2). However, because of the heterogeneity in effect sizes, it is possible that some of the genes may be differentially expressed in one or more neurodegenerative diseases, but not all. Because our goal is to identify a set of common genes that are differentially expressed in the same direction across all neurodegenerative diseases, we carried out "leave-one-disease-out" analysis. In this analysis, we repeated the meta-analysis four additional times, each time removing patient cohorts corresponding to one disease prior to analysis of the remaining patient cohorts for the other three diseases. Genes that remained significantly differentially expressed (FDR ≤ 5%) in all four iterations of the "leave-one-disease-out" analysis were considered to represent the common genes dysregulated across neurodegenerative diseases. We identified 322 such consistently differentially expressed genes (95 up-regulated, 227 down-regulated) irrespective of which subset of neurodegenerative diseases were analyzed (Additional file [1](#MOESM1){ref-type="media"}: Table S3). It is possible that there may still be significant heterogeneity in the effect sizes of these genes between different neurodegenerative diseases; however, this heterogeneity may indicate that the same pathway is expressed at different levels between neurodegenerative diseases, but in the same direction. Therefore, we did not further consider this heterogeneity for the 322 genes. Next, we validated these genes in three additional patient cohorts of neurodegenerative disease consisting of 985 samples (643 cases, 342 controls) (Table [1](#Tab1){ref-type="table"}, Additional file [1](#MOESM1){ref-type="media"}: Table S1) \[[@CR30]\],\[[@CR38]\]. These data sets profiled human post-mortem CNS tissue samples from patients with AD or HD. Large validation data sets were not publicly available for PD and ALS. We found 73/95 (76.8%) up-regulated genes and 170/227 (74.9%) down-regulated genes (total of 243 genes) were also significantly differentially expressed in the validation cohorts (Figure [2](#Fig2){ref-type="fig"} and Additional file [2](#MOESM2){ref-type="media"}: Figure S1). Henceforth, these 243 validated genes are referred to as a common neurodegeneration module (CNM) (Table [3](#Tab3){ref-type="table"} and Additional file [1](#MOESM1){ref-type="media"}: Table S4).Figure 2Meta-analysis and leave-one-disease-out analysis reveal common differentially expressed genes across neurodegenerative diseases. Heat map shows consistent differential expression in the discovery, validation, and secondary validation data sets. Columns denote CNM genes ranked from highest to lowest standardized mean difference (Hedges' g in log2 scale), from left to right. Rows denote data sets used in each stage of meta-analysis. Heat map colors indicate Hedges' g in log2 scale. Refer to Table [1](#Tab1){ref-type="table"} for data set information. ALS, amyotrophic lateral sclerosis; HD, Huntington's disease; PD, Parkinson's disease; AD, Alzheimer's disease; PiD, classical Pick's disease; FTLD, frontotemporal lobar dementia (Constantinidis type C); PSP, progressive supranuclear palsy; FTLD-GRNpos, frontotemporal lobar dementia with ubiquitin- and TDP-43-positive inclusions, progranulin mutation positive; FTLD-GRNneg, frontotemporal lobar dementia with ubiquitin- and TDP-43-positive inclusions, progranulin mutation negative. ######
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253, 1821, 13, 187 ]	? This man, Mrs. Kennedy, has saved my life and honour more than once, and it is no humiliation for me to go on my knees before him." Perhaps there was something in her face and the tone of her voice that touched the Englishwoman's heart, in spite of her outraged sense of propriety. The stern expression disappeared from her features, and she said with friendly, almost motherly gentleness-- "Come, my poor child! I have certainly no right to set up for a judge of your actions. But I am certainly old enough for you to trust in me." Edith, overcome by this sudden kindness, leaned her head on Mrs. Kennedy's shoulder. Heideck felt it would be best to leave the two ladies to themselves. "If you will permit me, ladies, I will leave you for the present." With a rapid movement Edith laid her hand upon his arm. "You give me your word, Captain Heideck, that you will not leave without saying good-bye to me?" "I give you my word." He left the room in a most painful state of mind. It seemed as if, in the fulfilment of his duty, he would have to pass over the body of the being who was dearest to him on earth. In the evening Mrs. Kennedy's maid brought him a short note from Edith, asking him to come to her at once. He found her in her dimly-lighted room on the couch; but as he entered she got up and went to meet him with apparent calmness. "You are right, my friend; I have in the meantime come to my senses again. Nothing else is possible--we must part." "I swear to you, Edith--" "Swear nothing. The future is in God's hands alone." She drew from the ring-finger of her left hand the hoop-ring, set in valuable brilliants, which had given rise to their first serious conversation. "Take this ring, my friend, and think of me whenever you look at it." Tears choked her utterance. "Have no anxiety for me and my future. I am going with the Kennedys to England." XXV A SUSPICIOUS FISHING-SMACK A raw north wind swept over the island of Walcheren and the mouth of the West Schelde, ruffling into tiny waves the water of the broad stream, which in the twilight looked like a shoreless sea. Only those acquainted with the ground knew that the flashing lights of the beacons at Flushing on the right and at Fort Frederik Hendrik on the left marked the limits of the wide mouth of the harbour. Here, in 1809, when Holland was under the rule of Napoleon Bonaparte, a powerful English fleet had entered the Schelde to attack Flushing, and take the fortress. In the centre, between the two lights, which were about three miles apart, the German cruiser Gefion lay tossing at anchor. On the deck stood Heideck, who on his return had been promoted to major and appointed to the intelligence department for the coast district of Holland. In the afternoon he had seen a vessel entering the Schelde, which the pilot had identified as one of the fishing-smacks plying between the Shetland Islands and the Dutch ports. Heideck had informed the captain of the Gefion of his suspicion that the smack might be intended for another purpose than trading in herrings. The little vessel had put in on the left bank, between the villages of Breskens and Kadzand, and Heideck decided to row across to it. Six marines and four sailors, under the command of a mate, manned one of the Gefion's boats, and set out for the left bank in the direction of the suspected vessel. It cost the oarsmen, struggling with the tide and wind which came howling from the sea, nearly half an hour's hard work before they saw the dark hull of the smack emerging clearly outlined before them. A hoarse voice from on board asked what they wanted. "His Majesty's service!" answered Heideck, and, as the boat lay to, he threw off his cloak, so as to spring on deck more easily. Three men, in the dark, woollen smock and tarpaulined hat of coast fishermen, approached him and, in answer to his inquiry for the master, told him, in an unintelligible mixture of Dutch and German, that he had gone ashore. "His name?" "Maaning Brandelaar." "What is the name of this vessel?" "Bressay." The answers were given with hesitation and sullenly, and the three men showed such evident signs of irritation that Heideck felt they would have gladly thrown him overboard had it not been for the respect inspired by his uniform. "Where from?" he asked. "From Lerwick." "Where to?" "We are going to sell our herrings. We are respectable people, Herr major." "Where are you going to sell your herrings?" "Where we can. The skipper has gone to Breskens. He intended to be back soon." Heideck looked round. The smack had put to in a little bay, where the water was quiet. The village of Breskens and the little watering-place, Kadzand, were both so near that the lighted windows could be seen. It was nine o'clock--rather late for the business which Maaning Brandelaar intended to transact at Breskens. Heideck sent the marines on deck with orders to see that no one left the ship before the captain returned. He then ordered a lantern to be lighted to examine below. It was a long time before the lantern was ready, and it burned so dully that Heideck preferred to use the electric lamp which he always carried with him as well as his revolver. He climbed down the stairs into the hold and found that the smell of pickled herrings, which he had noticed on deck, was sufficiently explained by the cargo. In the little cabin two men were sitting, drinking grog and smoking short clay pipes. Heideck greeted them courteously and took a seat near them. They spoke English with a broad Scotch accent, and used many peculiar expressions which Heideck did not understand. They declared they were natives of the island of Bressay. Heideck gathered from their conversation that the smack belonged to a shipowner of Rotterdam, whose name they appeared not to know or could not pronounce. They were very guarded and reserved in their statements generally. Heideck waited half an hour, an hour--but still no signs of the captain. He began to feel hungry, and throwing a piece of money on the table, asked whether they could give him anything to eat. The fishermen opened the cupboard in the wall of the cabin and brought out a large piece of ham, half a loaf of black bread, and a knife and fork. Heideck noticed two small white loaves in the cupboard amongst some glasses and bottles. "Give me some white bread," said he. The man who had brought out the eatables murmured something unintelligible to Heideck and shut the cupboard again without complying with his request. His behaviour could not help striking Heideck as curious. He had, as a matter of fact, only asked for white bread because the black was old, dry, and uncommonly coarse; but now the suspicion forced itself upon him that there was some special meaning behind the rude and contemptuous manner in which his request had been received. "You don't seem to have understood me," he said. "I should like the white bread." "It belongs to the captain," was the reply; "we mustn't take it." "I will pay for it. Your captain will certainly have no objection." The men pretended not to hear. Heideck repeated his request in a stern and commanding tone. The men looked at each other; then one of them went to the cupboard, took out the white bread, and set it on the table. Heideck cut it and found it very good. He ate heartily of it, wondering at the same time why the men had been so disobliging about it at first. When he took up the bread again to cut himself off a second piece, it occurred to him that it was remarkably heavy. He cut into the middle and, finding that the blade of the knife struck on something hard, he broke the loaf in two. The glitter of gold met his eyes. He investigated further and drew out, one after the other, thirty golden coins with the head of the Queen of England upon them. Thirty pounds sterling had been concealed in the loaf. "Very nourishing bread of yours," said he, looking keenly at the men,
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That it let your other brother pet him? Or could it—?” Carla told Wynter to behave. “Yes, ma’am, but you have to realize that I’m in over my head here. I’m a good person. Or I try to be. Why is all this crap going on?” “I would imagine that it has a great deal to do with what you are.” He looked at the dragons. “They’re a matched pair. And from what I’ve been told from my brothers, when yours was on your leg, it looked just like the one on my back. We, I guess you could say, were meant to be together.” “That is right, my lord. Since the beginning of the end of dragons, you were meant to be with a female that would be your match and mate in all things.” The female dragon laid her head down on the floor and the male joined her. “We have been waiting for generations for you, Wynter Snow. I think we were ready to give up hope that you’d ever be born.” “Great, I was born to be a screw up.” Tristan laughed. “What do you find so funny? If they’re right, and at the moment I can’t see anything wrong with their logic, then we’re together. But I’m going to be spending the rest of my life behind bars, if they don’t put me to death instead.” “There will be no sentencing for any of those. I’ve spoken to my brother, and he said that you’re going to be exonerated for the mall incident, as well as what happened at the hospital.” She asked him what had gone on there. “You disappeared.” “Oh, yes, well, your brother freaked us all out with the dragon. Did they tell you that he rose up from my flesh so that he could pet him? What sort of fucked up shit is that?” She looked at her mom. “I’m sorry, Mom, but you have to agree—it’s messed up.” “I do agree. But what happens now? I mean, other than that the dragon is no longer a part of her.” The male dragon stood up. “Do you know what happens now? I don’t even know what to call you.” “We have no names as yet, my lady. We are just male and female dragon.” Wynter asked if they were to name them. “If you wish to name us that would be fine. But it does not matter to us. We both belong to the two of you. We are mates as well.” “Does this mean that I can’t shift into my dragon anymore?” That had only just occurred to him. And it would piss him off if he weren’t able to fly anymore. Male told him that he could. So could the young miss. “She’s able to be a dragon?” “Wait, wait, and wait. I don’t want to be a dragon. No offense to you guys, but I’m happy being the plain old human that I am.” Tristan told her that she wasn’t human, never had been. “Oh, but you’re wrong about that. I’m a human, damn it, and you’d better not be fucking around with me to make me anything else.” “You’re immortal too.” He had no idea—insanity, he supposed—why he was aggravating Wynter like he was. She sure had a fine temper, and she was very expressive with her hands. Like the way she doubled up her fist at him. “You can’t hurt me.” “Why not?” He told her. “I’m not going to be your mate. It has nothing to do with this shit…stuff going on with the dragons, but I’m bad luck. I don’t even like to be around my mom so much—I don’t want her to be dragged into my trouble.” “I’m sure that it was all because you were going to meet me this way.” He didn’t even glance at the dragons, fearful that they’d tell him that that wasn’t it. “We’re going to get this all cleared up, and once we do, then you and I will live happily ever after.” “You’re certifiable; you know that, don’t you?” He grinned at her. “You’re not charming either. No matter how many other women have told you that. As a matter of fact, why don’t you go out and find one of them now? I’m sure they’ll be thrilled to see you.” “I’m not leaving you. We have a lot to talk about.” She said that she was done talking to him. “I’m sorry that you feel that way, Wynter. But there are a great many things going on that we have to figure out. Like, why were you created with a dragon on your leg and not your back? Who were you parents? Where were they for all those decades before you were born? There are a great many things that we have to figure out. Plus, keeping you safe needs to be a priority—I don’t want anything to happen to you. For some reason, and I don’t know why we’ve never thought of this before, someone wants you to be in prison. To get you alone, perhaps? I don’t know. But it bears talking about.” Clara stood and so did Tristan. “I need to use the restroom. I don’t know that I’ll return here, because I think that Lord Manning is correct. You both need to talk things out. In the meantime, I’ll be making arrangements for a hotel or someplace that we can stay until we get those answers.” “I have a large house that we can all live in together.” Clara told him that was all right, but she could find something. “I insist. I can keep an eye on you both, and if Wynter wants, she can become her dragon. There is plenty of room for that too.” Clara left and Tristan stayed where he was. Wynter was jumpy enough without him lying on the bed with her like he wanted. Instead of talking to her about anything serious, he started telling her about himself. “I’ve been around for a very long time. When we were born, we were dragons; the world was a much different place than it is now. We, the dragons, blackened the skies when we were around. Helping out our human friends was easy for us. Then they realized that we were worth much more dead than alive.” Wynter told him she was sorry. “Thank you. My mother, she’d been killed some months before my father gave his life for us to be human. And since then, we’ve been trying our best to blend in with humanity so they’d not kill us.” “I don’t understand any of this.” He said that he understood. They both looked at the dragons. “Do you really think it’s possible that I could turn into a dragon? Being that size would make people back off from me a little, don’t you think?” “You’ll be much larger than them.” She looked at him. “Wynter, I know this is a great deal to throw at you, but we really do need some answers. Mostly it has to do with why you’re a dragon that no one told us about. Why are we paired with matching dragons? My head is overwhelmed with all this. I can’t imagine what is going through yours right now.” “My wound is healed. I’m betting if they remove this cast that I’ll be all right there as well. Is that part of the magic?” He nodded. “I’m terrified out of my mind right now. And all I can think about is you wrapping me up in your arms and holding me. Not that I’m asking you to do that, but I just need one thing to go normally. I really could use a dose of normal about now.” “I’m afraid that went out the door with yesterday’s wash.” They both laughed. “Come on downstairs and we’ll have something to eat, and talk. I’m sure that Winnie or Carson has the others tied to a chair or something to keep them away.” “I don’t have anything to wear but this gown from the hospital.” She looked down at herself. “What I wouldn’t give for a nice thick pair of socks and some warm pants and a too large sweatshirt.” Before he could tell her to watch what she wished for, she was dressed in what she’d said. He had to admit, he thought, she certainly looked more comfy. When he started to tell her that she could do that, to change out of her outfit too, Wynter put her hand up. “I don’t want to talk about it. Nothing happened, all right? Please?” He nodded at her. “Good. I got dressed, and now I’m going to eat. I’m sure nothing will pop out of the kitchen in front of me, will it?” “I have no idea anymore.” She nodded and took his hand. The dragons said that they’d see them downstairs, as they needed to stretch their wings. “Do you want to watch them fly? It’s beautiful, and perhaps—” “No. There are no dragons. I’m visiting an old friend and I had a frightful dream, that’s all.” Tristan laughed and she grabbed his balls in her hand. “Don’t make me have to test that theory of yours
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15, 34987, 15, 20812, 15, 9104, 15, 20812, 15, 8193, 15, 24581, 15, 2640, 53, 3231, 313, 7913, 575, 45, 6006, 18, 13146, 18, 15, 3439, 15, 3763, 15, 15645, 15, 28953, 15, 1099, 15, 29579, 15, 1229, 15, 3121, 17659, 95, 21, 17977, 47, 313, 41829, 575, 45, 6006, 18, 13146, 23735, 15, 1252, 15, 22, 1252, 2941, 15, 4529, 15, 1839, 7716, 95, 20, 17977, 47, 313, 41829, 575, 45, 6006, 18, 13146, 520, 4148, 10683, 15, 48793, 15, 1508, 10496, 30311, 15, 21378, 15, 18, 25697, 313, 41829, 575, 45, 6006, 18, 13146, 2270, 19490, 14403, 15, 23695, 15, 20812, 24424, 19631, 15, 31408, 15, 21, 5964, 95, 21, 17977, 49, 313, 41829, 575, 45, 6006, 18, 13146, 17786, 15, 40187, 15, 3439, 520, 2504, 15, 12582, 15, 26, 12261, 313, 41829, 575, 45, 6006, 18, 13146, 22, 3031, 15, 46878, 15, 17884, 1671, 1166, 15, 2511, 15, 23, 13614, 313, 7913, 575, 45, 6006, 18, 13146, 520, 15, 18911, 15, 45827, 15, 1857, 520, 15, 10695, 15, 35366, 15, 22, 35811, 313, 7913, 575, 45, 6006, 18, 13146, 361, 15, 16129, 15, 7749, 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15, 71, 965, 405, 463, 8754, 405, 254, 67, 999, 797, 1947, 15, 615, 31, 558, 45107, 285, 47820, 452, 644, 2684, 970, 20753, 3231, 48, 577, 15, 22, 313, 350, 12963, 518, 285, 3774, 300, 17146, 1008, 1311, 3156, 9259, 285, 810, 37761, 452, 644, 1160, 970, 500, 4548, 884, 313, 52, 1719, 1008, 1311, 1237, 2498, 187, 187, 9340, 1712, 4538, 1012, 94, 187, 6877, 187, 187, 14444, 3828, 2538, 387, 329, 49980, 17457, 10744, 1712, 4538, 1047, 94, 187, 1013, 187, 187, 8639, 253, 9902, 13, 253, 6919, 273, 3846, 20341, 653, 33483, 7139, 905, 6924, 285, 1066, 264, 13, 8994, 22, 14, 3591, 9080, 387, 5988, 4898, 313, 5470, 73, 31148, 275, 1675, 273, 253, 16387, 14777, 369, 670, 3307, 575, 6, 313, 1470, 15, 575, 60, 22, 1084, 1470, 22, 910, 709, 14, 881, 568, 926, 2536, 380, 807, 846, 253, 9902, 13, 436, 6919, 2559, 281, 4567, 575, 7739, 496, 253, 1563, 1107, 13, 253, 1180, 273, 3846, 20341, 653, 33483, 7139, 21051, 2559, 407, 8611, 219, 22, 575, 6, 7194, 347, 271, 1055, 273, 21939, 28868, 868, 15, 6408, 253, 11526, 19543, 275, 4332, 13, 2067, 273, 253, 954, 5876, 14777, 497, 417, 16387, 13, 347, 352, 369, 2783, 1512, 8312, 281, 4901, 253, 37045, 273, 13547, 20131, 15, 187, 187, 510, 767, 4465, 10242, 2370, 273, 21939, 28868, 282, 2192, 35804, 275, 4748, 2692, 326, 21939, 28868, 868, 5876, 10323, 512, 653, 579, 707, 8994, 22, 575, 3591, 14073, 73, 15, 7214, 470, 15, 24, 283, 19, 575, 6, 273, 253, 7139, 497, 30195, 313, 13074, 1180, 273, 6949, 7139, 13, 475, 79, 11, 575, 30, 575, 740, 3357, 481, 23177, 273, 253, 7139, 574, 5884, 8540, 313, 2437, 374, 481, 5595, 273, 841, 7139, 858, 417, 1818, 966, 875, 253, 767, 17276, 15, 17842, 5403, 285, 4695, 13, 1722, 575, 6, 273, 253, 20341, 653, 33483, 7139, 4962, 15, 6408, 253, 5768, 4748, 13, 1529, 854, 575, 6, 273, 253, 7139, 4962, 15, 496, 4332, 13, 359, 5950, 326, 2568, 1529, 1903, 575, 6, 273, 253, 20341, 653, 33483, 7139, 574, 4962, 15, 1723, 13, 436, 7155, 943, 320, 2686, 2169, 347, 2067, 14777, 342, 7418, 3846, 285, 1066, 264, 7139, 497, 10432, 432, 253, 4332, 19543, 1955, 281, 5252, 4606, 15, 187, 187, 510, 4585, 3486, 407, 253, 21939, 28868, 868, 369, 327, 4067, 7139, 15, 1198, 20341, 653, 33483, 7139, 342, 37162, 4398, 938, 575, 3591, 13, 253, 6919, 273, 3846, 7139, 591, 7484, 369, 670, 253, 1072, 275, 512, 253, 1740, 10242, 2370, 15, 1198, 4067, 7139, 13, 253, 6919, 273, 3846, 7139, 2559, 31063, 275, 253, 4332, 19543, 313, 1470, 15, 575, 60, 23, 1084, 1470, 23, 910, 709, 14, 881, 568, 926, 2536, 1470, 15, 575, 23, 39, 3460, 273, 3846, 20341, 653, 33483, 591, 18855, 9080, 966, 387, 10242, 2370, 323, 1027, 1107, 387, 329, 49980, 17457, 10744, 187, 187, 47, 10682, 2538, 387, 329, 49980, 17457, 10744, 1712, 4538, 1010, 94, 187, 28693, 187, 187, 2512, 497, 642, 25488, 326, 253, 9902, 269, 3485, 275, 4247, 5826, 4269, 667, 2559, 427, 6299, 275, 13710, 275, 253, 759, 37968, 4172, 1148, 757, 31344, 313, 1470, 15, 575, 60, 24, 1084, 1470, 24, 910, 709, 14, 881, 568, 926, 13334, 5270, 575, 60, 20, 1084, 10297, 20, 910, 709, 14, 881, 568, 2420, 2536, 496, 253, 378, 14, 1688, 21148, 13, 2299, 13, 253, 7651, 95, 20, 17977, 47, 4719, 369, 3012, 2169, 846, 253, 21939, 28868, 282, 2983, 2796, 81, 11, 575, 4713, 575, 17, 15, 1762, 10, 313, 1470, 15, 575, 60, 24, 1084, 1470, 24, 910, 709, 14, 881, 568, 926, 13334, 5270, 575, 60, 20, 1084, 10297, 20, 910, 709, 14, 881, 568, 2420, 2536, 831, 5876, 253, 24758, 6299, 347, 973, 342, 3012, 2169, 24758, 6299, 275, 253, 1340, 27, 19039, 575, 4713, 575, 998, 526, 269, 3485, 575, 4713, 575, 35, 782, 28868, 282, 2180, 313, 3235, 575, 60, 20, 1084, 10297, 20, 910, 709, 14, 881, 568, 2420, 2536, 25373, 323, 387, 495, 15, 19, 14, 78, 8825, 6864, 275, 253, 10444, 8232, 13, 4645, 3012, 2406, 18020, 95, 21, 17977, 47, 6299, 1309, 253, 9902, 14, 71, 3485, 2180, 13, 642, 3910, 875, 9894, 497, 1119, 323, 427, 275, 23765, 275, 253, 48625, 3672, 285, 10444, 18192, 15, 496, 253, 10143, 2170, 13, 2299, 13, 3012, 2169, 18020, 95, 21, 17977, 47, 285, 24758, 6299, 497, 1119, 1309, 253, 21939, 28868, 282, 2180, 1097, 387, 337, 15, 17, 14, 78, 285, 374, 15, 17, 14, 78, 8825, 24484, 13, 1223, 6714, 7651, 95, 20, 17977, 47 ]	identification of taxa, and organic material analyses. ### Stream water {#Sec11} At Stora Göljån, stream water was sampled on a monthly basis. Before the flashflood, the samples were collected from a bridge just downstream the benthic macroinvertebrate sampling site. After the flashflood, this stream channel was clogged, and the samples were taken from shore just downstream the new benthic fauna sampling site. The water was collected in rinsed polyethylene bottles and before 2009, sent for chemical analysis to the SWEDAC accredited MEANA laboratory in Uppsala. From January 2009 and onwards, the samples were sent to the laboratory at the Department of Aquatic Sciences and Assessment, SLU for chemical analysis. Except for PO~4~^3−^ and TP, the two laboratories used the same analytic methods, and SO~4~^2−^ and Cl^−^ were in fact analyzed at SLU ([@CR37]) throughout the monitoring period. At MEANA, PO~4~-P and TP were manually analyzed in a 5-cm quartz cuvette. Statistical analyses {#Sec12} -------------------- The Aneboda IM SW, GW, and stream water N concentration time series were separated into Reference (before January 8, 2005), Storm-felling (January 8, 2005--December 31, 2007) and Bark beetle periods (after January 1, 2008). Differences in N concentrations between periods were tested by the Kruskal--Wallis test followed by a post hoc comparison for each pair using Bonferroni-corrected Wilcoxon test (JMP version 10.0.2d1). Due to the restricted number of observations on TN during the storm-felling period for SW (n = 3--15 per season and soil stratum) and GW (n = 3 per season and sampling site for all N compounds), we have not tested for seasonality. In total, eight metrics describing the macroinvertebrate assemblage structure for each sampling occasion (spring and autumn) and year were calculated, and due to statistical differences in macroinvertebrate metrics between seasons, further analysis was separated by season. However, due to the lack of autumn samples and the limited number of spring samples prior to the catastrophic event, we were not able to perform any statistical tests on differences between metrics before and after the storm. The eight biological metrics were used to analyze possible changes in diversity and composition of macroinvertebrate assemblages. Taxon richness was selected as a qualitative measure of changes in assemblage diversity. In addition, assemblage diversity was calculated as Shannon (Shannon and Weaver [@CR35]) and Simpson (Simpson [@CR36]) diversity as well taxon distinctness. The latter is a diversity measure based on the relatedness of the species within a sample (Warwick and Clarke [@CR47]). Further, a detrended correspondence analysis (DCA) was performed to show temporal changes in taxonomic composition. DCA is an unconstrained ordination technique, which finds the main factors/gradients in large, species-rich, but usually sparse data matrices (ecological community data). Simple linear regression analyses with metrics versus time were performed to display possible changes in metrics over time, especially focused on the time after the event. To evaluate the relationships between macroinvertebrate assemblages and environmental factors and to assess which factors that can explain changes in the species assemblage of benthic macroinvertebrates over time, a canonical correspondence analysis (CCA) was performed with physicochemical data, including organic substrate parameters expressed as AFDW (Table [2](#Tab2){ref-type="table"}).Table 2Minimum, maximum, and mean (±1 SD) values of water chemistry and organic substrate (AFDW mg) variables across all years, but separated in autumn and spring samples at Stora Göljån, used in the CCAAutumnSpringMinMaxMeanSDMinMaxMeanSDpH56.596.210.475.416.56.120.30Conductivity (mS m^−1^)0.841.921.220.220.841.671.160.22Alkalinity (meq L^−1^)−0.020.060.040.0200.060.030.02Absorbance (420 nm)0.030.070.050.010.050.120.080.02TOC (mg L^−1^)1.54.62.450.803.25.484.30.76NH~4~-N (µg L^−1^)274.201.520103.92.38NO~3~-N (µg L^−1^)0197123.547.23015677.238.1TN (µg L^−1^)90245192.340.050357193.473.4PO~4~-P (µg L^−1^)185.761.540147.022.9TP (µg L^−1^)5199.613.0403517.89.6Ca (mg L^−1^)01.320.910.4501.800.980.5Mg (mg L^−1^)00.190.110.0500.180.110.05SO~4~ (meq L^−1^)0.020.030.030.010.010.040.030.01Organic substrate Detritus (mg AFDW)19.8202.652.847.316.50180.5261.943.34 Fontinalis sp. (mg AFDW)07.741.052.42096.912.331.8 Sphagnum sp. (mg AFDW)0000026.021.726.5 Periphyton (mg AFDW)035.47.189.58035.99.0410.05 Other (mg AFDW)0249.362.583.2043172.8114.9 Metrics have been calculated using Asterics version 3.3.1 (<http://www.fliessgewaesserbewertung.de>); DCA and CCA have been performed using CANOCO 4.5 (ter Braak and Smilauer [@CR41]); and regressions have been made using JMP 10 (SAS [@CR32]). Results {#Sec13} ======= Tree layer effects at Aneboda IM {#Sec14} -------------------------------- Before the storm, the fraction of dead Norway spruce trees \[standing and downed, \>5-cm diameter at breast height (dbh)\] in respect of the monitored plots was about 22 % (Fig. [5](#Fig5){ref-type="fig"}). The year after the storm, this fraction increased to 32 %. In the following years, the number of dead Norway spruce trees annually increased by ≈5 % mainly as an effect of bark beetles. During the scheduled inventory in 2011, several of the most affected plots were not monitored, as it was considered too dangerous to enter the maze of fallen logs. The two extra inventories of bark beetle infestation in 2009 showed that bark beetles affected basically all spruces \>5 cm dbh. Only 0.7--2 % of the trees were unaffected (total number of investigated trees, n = 1053). Half of the trees had minor damages (class 2). Most of these trees did not change class between the two surveys. Between 2006 and 2008, 17 % of the Norway spruce trees died. During the summer 2009, another 8 % of the trees died. In 2011, we recorded that yet another 11 % of the Norway spruce trees had died. However, this percentage should be actually higher as several plots with numerous dead and downed trees were excluded from the 2011 inventory due to safety reasons. The highest impact by the bark beetles was on larger trees. For Norway spruce trees with diameters \<20 cm, the fraction of dead trees per plot was about the same in all the four inventories. For larger trees, the fraction of dead trees increased drastically in the 2011 inventory (Fig. [6](#Fig6){ref-type="fig"}).Fig. 6Fraction of dead Norway spruce per trunk diameter class at inventories for different years at Aneboda IM Nitrogen effects at Aneboda IM {#Sec15} ------------------------------ There were no indications that the storm felling in January 2005 caused any increased N concentrations in SW in the peaty riparian soils (Fig. [7](#Fig7){ref-type="fig"}; Table [3](#Tab3){ref-type="table"}). In the B-horizon, however, the NO~3~-N concentration was significantly higher after the bark beetle attack (p \< 0.05) (Fig. [7](#Fig7){ref-type="fig"}; Table [3](#Tab3){ref-type="table"}). This affected the TN concentrations as well with significantly higher TN concentrations in the order: Reference \< Storm felling \< Bark beetle period (Table [3](#Tab3){ref-type="table"}). Except for at 3.2-m soil depth in the intermediate zone, showing significantly lower NH~4~-N concentrations during the storm-felling period, no differences between periods were found for N in GW in the recharge areas and intermediate zones. In the discharge area, however, significantly higher NH~4~-N and TN concentrations were found during the bark beetle period both at 1.0-m and 2.0-m soil depths, while excess NO~3~-N
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346, 531, 14, 1342, 14, 4152, 3, 310, 271, 2060, 665, 187, 42241, 247, 1180, 273 ]	(0, -90, 0), turn-left (90, 0, 0), turn-right (-90, 0, 0) Shake normal normal </COMMENTFIXEDWIDTH> </COMMENT> <COMMENT> <COMMENT_HEADING>* Meanings of Presets</COMMENT_HEADING> <COMMENT_DATA> "Happy" means a 180 degree semi-circle, clockwise from the 3 o'clock position. "Sad" means a 180 degree semi-circle, clockwise from the 9 o'clock position. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Maximum Gesture Size</COMMENT_HEADING> <COMMENT_DATA> There is no formal maximum size for a gesture, for example a circle gesture could require the user to move several times round the circle. However if the user draws such a gesture very slowly it's possible that too many stylus move points could be generated, and the gesture wouldn't be detected. The plugin has been tested with a circle gesture from 0 to 720 degrees and taking approximately 6 seconds to draw without problem. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Compatibility with other APIs and settings</COMMENT_HEADING> <COMMENT_DATA> Gestures may behave strangely on some devices if you are using Finger Scrolling or if you have any of the debug buttons displayed like the 'backbutton' or 'forwardbutton'. Particularly with the IE engine the screen will also scroll behind the gesture or the diagnostics will not persist respectively. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Common Pitfalls</COMMENT_HEADING> <COMMENT_DATA> Do not use alert boxes within the Gesture-Detected Callback, doing so will steal focus from the gesture region. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Out-of-range Values</COMMENT_HEADING> <COMMENT_DATA> Any parameter values out of the allowed range will be limited to the nearest allowed value. E.g. giving a sensitivity greater than 100 will use 100. Numeric parameters given as text will be treated as zero. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Diagnostics</COMMENT_HEADING> <COMMENT_DATA> Note that diagnostics exist only for the purpose of understanding and evaluating the various parameters. They should not be enabled in the release version of the code. They may also not display correctly in every circumstance, e.g. when scrolling, or for certain sets of parameters, e.g. for nearly vertical linear gestures. Diagnostics are not available for Tilt and Shake gestures. </COMMENT_DATA> </COMMENT> </REMARKS> <EXAMPLES> <EXAMPLE> <DESC> Create two gestures: a default left to right gesture with ID 'swipe', and a hold gesture at the top left of the screen which will fire one time after 500 milliseconds with ID 'press'. The Javascript function onGesture() is called when either gesture is detected. </DESC> <CODE> <META HTTP-Equiv="gesture" Content="type:linear"> <META HTTP-Equiv="gesture" Content="id:swipe"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture" Content="type:hold"> <META HTTP-Equiv="gesture" Content="center-x:60"> <META HTTP-Equiv="gesture" Content="center-y:60"> <META HTTP-Equiv="gesture" Content="radius:60"> <META HTTP-Equiv="gesture" Content="delay:500"> <META HTTP-Equiv="gesture" Content="interval:0"> <META HTTP-Equiv="gesture" Content="id:press"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture-detected" Content="url('Javascript:onGesture('%s','%s');')"> </CODE> </EXAMPLE> <EXAMPLE> <DESC> The following example deletes a gesture via a javascript function. </DESC> <CODE> function deleteGesture(gestureID) { gesture.id = gestureID; gesture.delete(); } </CODE> </EXAMPLE> <EXAMPLE> <DESC> Create 3D gestures: a tilt gesture that is called when the device is placed in upright position and a shake gesture. The Javascript function onGesture() is called when either gesture is detected. </DESC> <CODE> <META HTTP-Equiv="gesture" Content="type:tilt"> <META HTTP-Equiv="gesture" Content="id:swipe"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture" Content="type:shake"> <META HTTP-Equiv="gesture" Content="id:shake"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture-detected" Content="url('Javascript:onGesture(%json);')"> <script type="text/javascript"> function onGesture(jsonObject) { var html = "<b>Gesture Detected: </b>" + jsonObject.id + ""; gestureOut.innerHTML=html; } </script> <DIV id="gestureOut">Gesture Output will appear here</div> </CODE> </EXAMPLE> </EXAMPLES> <ADDITIONAL> <PLATFORM>All supported devices. On Windows the tilt and shake gestures are supported only on MPA3.0 devices.</PLATFORM> <APPLIES>Transient - any changes made by changing parameters will be lost when navigating to a new page.</APPLIES> <REQ>Linear, Circle and Hold gestures require a touch screen.</REQ> <VER_INTRODUCED>1.0.0</VER_INTRODUCED> </ADDITIONAL> <SEEALSO> <TOPIC RELPATH="../Getting Started/">GesturesOverview</TOPIC> </SEEALSO> </FUNC> </HELPPAGE> There are many good shows to watch on the Internet, like سكس في الحمام or سكسنيك من خلف. Do you like سكس أغتصاب or سكس في الحمام better? With the advancement of high broadband speeds, high definition streaming video is possible. Here on Shin SVS, you can search for سكس دينا رقاصه and سكس أغتصاب streaming Videos from popular video portals on the Internet like Youtube. Have a good time!Protection of femoral neck taper in revision of acetabular component. In hip revision restricted to the acetabular component, the taper of a modular stem is in constant danger of scratching. We used a plastic syringe to protect the taper of the femoral component. A plastic syringe of appropriate size remains well in place and offers a novel and inexpensive protective device for the taper of the femoral component available in every operation room.> Initial Number - counting starts here! > BBC 1 is the flagship television service of the BBC. > ITV 1 was the flagship television service of ITV, but it reverted to simply ITV in 2013. > Sky 1 is the prime general entertainment service of Sky Television. > Radio 1 is a radio service from the BBC, aimed at the younger generation. > Formula 1 is the highest level of motor racing regulated by the FIA (Fédération Internationale de l'Automobile). > Humans have 1 nose and 1 mouth, and 1 each of most vital organs.> A "one-man-band" is an individual who plays a number of
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275, 253, 987, 1039, 13, 253, 2165, 588, 1928, 1077, 8921, 15, 22746, 187, 187, 39, 10529, 1077, 1390, 2952, 13, 33386, 434, 3045, 544, 6434, 30, 2413, 1358, 2700, 15, 76, 69, 1200, 13347, 15, 316 ]	the fifth (41. 8%), the two quality and quantity. Consumed together, the three points to thrown into space isn't an easy thing, should have the forty percent three-point shots have to create his own shots, this how tired! The most precious is, no make a difference when and where, and how to make simple moves, garage has a superior percentage. It is no wonder the manager of the a warrior when Bob myers recently told the Associated Mass media said: "as long seeing that it's garage, to find the ball is reasonable. ". Finals past season, Arsenal's performance [url=http://www.kdshoes.us.com]kevin durant shoes[/url] isn't very ideal, although the info well, but the efficiency is not high, and his again pass error, defensive irvine was manufactured key 3 points have grown to be a "black spots" moment, apparently, in hope that within this to prove himself. Simply no, after the opening, the three points inside database and didn't hit two shots, on this contrary, the knight about three points would hit a lot of over there. Garage or focus on defense, he para which include lebron, Irwin, JR., continues to be people already, also have successful prevention. In transferring, did well in your Treasury, the ball to your teammate are fed properly, but Mr Chu in a number of opportunity attack. 04 seconds left within the first quarter, garage dribble for the frontcourt, rhythm, but he could be confident the take a few steps away from the three-point line and it's necessary to make [url=http://www.curry-shoes.com]curry shoes[/url] actions, the ball! This can be the warriors in the very first 3-pointer today. Soon, the Treasury and using second chances for the right side of the beds base again in a 3 details! It is worth mentioning how the opening, the garage suitable arm was wearing a new black gear, it is also because his right elbow inside the game before the old injury carries a relapse, however, with the sport, he has to take off protective devices. Gear, this indicates, has affected the deal with, before he took off once i feel much better. Within against lebron James, the defense does very well in the Arsenal, but after he was lebron was a little daughter knocked out, the referee has [url=http://www.stephencurryshoes.com]stephen curry shoes[/url] blown the garage preventing foul, garage on the soil is various, make action on the referee said lebron knee. In breakthrough, garage is usually a difficult moves, a myriad of people all the approach up his defense, including lebron, but Treasury first in all kinds of dazzling dribble move Thompson, after air and rival crash cases, the hard in order to score. Throw three points isn't the whole garage everyday work, and don't forget about, Stephen curry is the team in assists in addition to steals, he averaged 6. 7 assists from the regular season, 14 in the league and the playoffs [url=http://www.stephencurryshoes.com]stephen curry shoes[/url] can be averaging 9. 3 assists because league the first! Let's imagine an image, 40 minutes per game inside the Treasury, attack launched lots of times, there are always several ball he wasn't within the outside, but the soccer ball inside, attracted a twice... What will happen and then? There was a man he'll tell you the answer, [url=http://www.curry-shoes.com]curry shoes[/url] he called clay : Thompson, from the older state warriors, he made there is much surprise 211 3-pointers, finished third inside the league, and that 211 3-pointers, 68 comes from the assists of Stephen curry. 12-13 time of year to contrast the storage area and ray Allen inside '05 -' 06 : Allen into 269 3-pointers, and he could be the Seattle supersonics. That year, Allen's 269 involving 653 three-point shots, chance 41. 2%, as Stephen -- 272 of 600 photographs in his Arsenal, as high as 45. 3%; That yr, Alan ball attack build 3 ratio is below a quarter, compared along with 38. 6% in data bank; That year, Allen's assists the number 3. 7, less compared to the Treasury for three helps. So the outline, the image of alternative 3-pointers hand down the garage outline: he not merely completed the sharpshooter backdrop, his teammates for the creation of free-throw options into; He will also look for opportunities as well, through the ball discovery, stopped for no allows 3-pointer of shots. Additionally, he also can move assists, "create" another glass pitcher - clay - Thompson! Not merely can catch vote, will urgent stopped, can develop more opportunities to other folks, this star, unique! I'm [url=http://www.kdshoes.us.com]kd shoes[/url] afraid, just use "striker" two words are actually unable to define Stephen curry, also have to be in with a new "great" rhetoric. Half-court finished,[url=http://www.stephencurryshoes.com]stephen curry shoes[/url] the garage 12 details and 4 rebounds 6 helps, Owen 17 rebounds, 2 assists 1 contains the upper hand slightly. But as knight defeat in the second half, even their one-on-one hit his things. In this series, OuWenBen should have certain advantages in counterpoint, such as finals last year, because season of Christmas competitions, with their strong particular fortunes turned. But today the warriors of the changes, let knights staggered, also let like one-on-one hit Owen [url=http://www.curry-shoes.com]curry shoes[/url] to search for the rhythm. Actually, today more often than not was clay - Thompson The almighty Owen, although Owen hit a dead before him, but clay height reach or up to a point, limits the Owen's invasion. In only a few times facing single singled out inside his Arsenal, although Owen possesses good performance, but also it's hard another for a knight. Total play, scored 28 points 6 rebounds and 10 assists inside the Treasury, 6 of 11 three-point [url=http://www.kdshoes.us.com]kevin durant shoes[/url] photographs. 24 points and 3 rebounds, a couple of assists, Owen has scored 17 points within the first half, he scored seven points within the second half. Facing the big four in the mighty, and only Jordan Owen in one-on-one win garage have chances, but today's garage to try and do better. Garage underneath the [url=http://www.stephencurryshoes.com]stephen curry shoes[/url] second dribbling is toward the switch on the left side with the body without any slowdown, the footsteps choiceness and quick, soon arrived at the position you would like to go. Unlike most pitcher like center of gravity down, then struggled to jump to complete, the garage action a lot more concise. Don't waste any hard work, just jump off the bottom, slightly triggered his firing action instantly. "He is not only the most pure great scorer, he even gave shot two words to make the definition, the whole shooting art played a new revolutionary role. "The bobcats head scout work Adam - Mr Libby said Treasury. Counter frames in 6 a few minutes and 31 seconds, garage from his upper body slightly next point position organized the ball, the index finger as well as middle finger instinct to get gaps in the plastic ball center. His hand gently lifted back, remaining his palm the basketball, but still control between his fingers. His right arm into all of the joints is close to help 90 degree Angle, in the shoulder to the elbow, from the elbow towards wrist, from wrist to consider, as if a cafe waiter in carrying the tray. Glen Davis clippers, 289 - pound in the front, [url=http://www.curry-shoes.com]curry shoes[/url] need to speed up their action in the Treasury, since the childhood to lay a great foundation for complete to garage in different state, the right arm and shooting are able to keep perfect posture and durability. And in addition to master hand movements, garage features a precise shot needed one more factor: enough deep muscle tissue memory. Shooting touch isn't a proper adjective, any player, able to throw a good shooting there is yet one secret to all - month after month, year after year practice, until a set involving complex dynamic chain implanted into muscle tissue. Garage never resist like monks meditate boring exercise, it also helped while he graduated from high school, eventually grow into a separate leading little-known Davidson college or university NCAA elite last seven. "Game changing, there is no time to [url=http://www.kdshoes.us.com]kevin durant shoes[/url] you feel about your own shooting action is correct, " curry explained, "you can only depend on their daily at it ground building muscle ram, hit and believe that any of us can. We're so many practice in training, to be able to the game, you can make use of instinct to react. But if it is not in the right way, the game will feel very strange. ". Finals very last season, Arsenal's performance [url=http://www.kdshoes.us
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disheartening, and bought with him things other people bought to have a good time together, as though by doing that we would have a good time, whereas I had no illusion that I would enjoy myself, or maybe I did think I could achieve something that would feel, at least for a little while, like a good time simply by going through the motions of it, that if I just carried on like that, my mood would suddenly change, and what had not been enjoyable would become enjoyable. Now I would like to be in that room again, on that night. I am curious to see what he would say and what I would answer, because I have forgotten so much of the way he talked and the things he might think of saying to me. Now I would bring so much interest to the meeting with him that it would be full of a kind of life it did not have then. There was no table where we could play cards, so we sat on the carpet by his bed. We drank the beer, ate the chips, and played gin rummy. The game was not interesting. I might have known, if I had been willing to think about it, that I could not hope for anything from the game itself, because if there was boredom between us, there would be no tension in the game either. We played on and on, as though trying to force some interest from it. We drank more beer than we wanted, or at least it was more than I wanted, and were not affected by it either. The alcohol seemed to have no more power to intoxicate me than the game had power to interest me, and the situation was not changed by it, as I had hoped it would be, knowing that alcohol could usually change a situation at least a little. We ate the chips and maybe other things as well before the chips, or maybe we had had something odd or excessive earlier, for dinner, because when we finally went to bed, I began to feel sick, and I lay awake feeling sick, and then my sickness became so bad that I kept going into the bathroom and sitting on the floor next to the toilet, my arms on the toilet seat and my head on my arms, and then on the toilet, and then down on the floor again next to the toilet, for most of the night. He woke up slightly, once, but did not seem to notice that I was going back and forth so often or was awake for so much of the night. The next day was his birthday. We went to a movie. After the movie, we went home to my house, ate thick sweet cake and ice cream, and sat on the foot of my bed while across the room, so large and empty that the bed at one end, and the piano, the card table, and the ugly metal chairs at the other seemed small on the expanse of dark tile floor, Madeleine, sitting on one of the hard chairs, read aloud to us in the light from one of the bare bulbs attached to the white plaster wall long, complex horoscopes from a magazine. Again I was uneasy, and sensed that without the food and Madeleine's company, there would have been emptiness between him and me, and boredom, that the presence of Madeleine, in fact, who was so separate from us, drew us together a little, at the same time that what she was reading was so entertaining, and beyond that, her own reactions to it were so sharp. I ate too much, and I laughed too much. But the food held most of my interest and attention as long as it lasted and I was restless as soon as it was gone. What did boredom mean then? That nothing more would happen with him. It wasn't that he was boring, it was that I no longer had any expectations for this companionship with him. There had been expectations, and they had died. And why did that boredom make me so uncomfortable? Because of the emptiness of it, the empty spaces opening up between him and me, around us. I was imprisoned with this person and this feeling. Emptiness, but also disappointment: what had once been so complete was now so incomplete. * * * The evening before I left on my last trip contains another memory that is difficult, not so much because of my bad feelings about him, I think, as because of a combination of other things: the awkward spaces and ugly concrete walls of the barnlike building where the reception was held, the sickening sweetness of the cheap white wine, the rain afterward, the bare lawn outside, with no plantings on it at all, and the word "reception," which I don't like. I was moving from one person to another, with a glass of that sweet wine in my hand, looking through the crowd from time to time, when suddenly I saw him standing there with a few of his young friends. I did not expect to see him, though now I can't think why I wouldn't have talked to him about the reception. This is the sort of question that bothers me the most, because I will never have an answer for it—what our relations were at that point, if I was planning to do something without him and without even mentioning it to him. Maybe that was not unusual for us, but it seems especially strange to me in this case, since I was leaving the next morning. I can't remember which friends he was with, or if I even noticed who they were, since I didn't care, and I can't remember if I went over to him as soon as I saw him or, remaining a few yards away, caught his attention and waved to him and continued to talk to other people, or didn't try to catch his attention but simply watched him and kept track of where he was in the room. The last seems the most likely to me, maybe because this is what I have believed all these years. But it was also something I would be likely to do, given the reaction I had when I saw him, a reaction I do remember unmistakably. It was a feeling of absolute displeasure to see him there, as though he were a hostile element in that place, a thing that intruded where it didn't belong, so that as I watched him among the moving figures, over the shoulders of the other people in the crowded place, those same features of his that had held such a positive attraction for me not long before, and that would exert such a fascinating force again not long after, were just then repugnant to me, blunt and deadly, primitive and vicious, without intelligence, without humanity, the color of clay. Rain was coming down hard and a few people gathered by the open door, preparing to run to their cars. Although I don't know how I came to stand by the door with him, I did go with him to my car, the two of us running across the sodden lawn under my umbrella or my raincoat, and I drove him the short distance to his own car. I certainly remember the spongy grass under my feet better than I remember what I said to him, or what he said to me. I was on my way out to dinner, and he was going off to some place where his friends were giving him a birthday party. He said he would come to my house late in the evening. By the time he came, I had been at work several hours on a job I had to do before I left in the morning, and although it was already late by then, I was not finished. He went to bed at the other end of the room and fell asleep. I worked on, impatient to be done with what had turned out to be much more tedious than I had thought it would be. I was checking a friend's translation, and I was doing it as a favor. The friend never really thanked me later, or not in any way proportionate to the amount of work I had done or the awkward moment when I had had to do it, though of course it wouldn't be fair to expect her to know how awkward that moment was, especially since even I did not know it was the last night I would spend with him. I finished and went to bed. He woke up, and then we talked to each other for close to an hour, unusually companionable and relaxed, as we might have been all along, as though we were taking our last chance for it. The next morning we got into his car and he drove me to the airport. I did not see him again until I came back more than four weeks later, when he met me at the same airport and we got back into the same car. He waited until we were on our way up the highway to begin telling me that everything had changed. The distance in him was enough to let me know something had happened, though he had said nothing about it in the corridors of the airport or by the revolving tables of luggage. The distance was there because he had already begun a different way of being with me, whereas I was still in the old way of being with him. * * * I lost most of another day of work yesterday, because Vincent and I took his father to the county fair. We put a cap on him because it was a blistering hot day, and as we wheeled him around he peered out at everything attentively from under his visor. We took him to see the sheds of cattle, sheep, rabbits, and poultry, and the rubber tires of his chair rolled pleasantly over the fresh sawdust. A goose put its beak to the wire grille of its cage and honked at him and he kissed his hand back to the goose. I don't know what he was thinking. I suppose we were trying to entertain him with a spectacle more unusual than his
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peacocks and its tears.” Yup, we definitely need to re-haul the way India views sex-education, as one Indian classical dancer takes on the challenge.What nonsense. People who buy Tabasco sauce do not travel on public transport in South Africa - they drive. And how exactly is someone driving past going to experience the heat factor? Answer: they can't.# Copyright 2017 The TensorFlow Authors. All Rights Reserved. # # Licensed under the Apache License, Version 2.0 (the "License"); # you may not use this file except in compliance with the License. # You may obtain a copy of the License at # # http://www.apache.org/licenses/LICENSE-2.0 # # Unless required by applicable law or agreed to in writing, software # distributed under the License is distributed on an "AS IS" BASIS, # WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. # See the License for the specific language governing permissions and # limitations under the License. # ============================================================================== """ResNet model. Related papers: https://arxiv.org/pdf/1603.05027v2.pdf https://arxiv.org/pdf/1512.03385v1.pdf https://arxiv.org/pdf/1605.07146v1.pdf """ from __future__ import absolute_import from __future__ import division from __future__ import print_function import tensorflow as tf class ResNet(object): """ResNet model.""" def __init__(self, is_training, data_format, batch_norm_decay, batch_norm_epsilon): """ResNet constructor. Args: is_training: if build training or inference model. data_format: the data_format used during computation. one of 'channels_first' or 'channels_last'. """ self._batch_norm_decay = batch_norm_decay self._batch_norm_epsilon = batch_norm_epsilon self._is_training = is_training assert data_format in ('channels_first', 'channels_last') self._data_format = data_format def forward_pass(self, x): raise NotImplementedError( 'forward_pass() is implemented in ResNet sub classes') def _residual_v1(self, x, kernel_size, in_filter, out_filter, stride, activate_before_residual=False): """Residual unit with 2 sub layers, using Plan A for shortcut connection.""" del activate_before_residual with tf.name_scope('residual_v1') as name_scope: orig_x = x x = self._conv(x, kernel_size, out_filter, stride) x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, kernel_size, out_filter, 1) x = self._batch_norm(x) if in_filter != out_filter: orig_x = self._avg_pool(orig_x, stride, stride) pad = (out_filter - in_filter) // 2 if self._data_format == 'channels_first': orig_x = tf.pad(orig_x, [[0, 0], [pad, pad], [0, 0], [0, 0]]) else: orig_x = tf.pad(orig_x, [[0, 0], [0, 0], [0, 0], [pad, pad]]) x = self._relu(tf.add(x, orig_x)) tf.logging.info('image after unit %s: %s', name_scope, x.get_shape()) return x def _residual_v2(self, x, in_filter, out_filter, stride, activate_before_residual=False): """Residual unit with 2 sub layers with preactivation, plan A shortcut.""" with tf.name_scope('residual_v2') as name_scope: if activate_before_residual: x = self._batch_norm(x) x = self._relu(x) orig_x = x else: orig_x = x x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 3, out_filter, stride) x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 3, out_filter, [1, 1, 1, 1]) if in_filter != out_filter: pad = (out_filter - in_filter) // 2 orig_x = self._avg_pool(orig_x, stride, stride) if self._data_format == 'channels_first': orig_x = tf.pad(orig_x, [[0, 0], [pad, pad], [0, 0], [0, 0]]) else: orig_x = tf.pad(orig_x, [[0, 0], [0, 0], [0, 0], [pad, pad]]) x = tf.add(x, orig_x) tf.logging.info('image after unit %s: %s', name_scope, x.get_shape()) return x def _bottleneck_residual_v2(self, x, in_filter, out_filter, stride, activate_before_residual=False): """Bottleneck residual unit with 3 sub layers, plan B shortcut.""" with tf.name_scope('bottle_residual_v2') as name_scope: if activate_before_residual: x = self._batch_norm(x) x = self._relu(x) orig_x = x else: orig_x = x x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 1, out_filter // 4, stride, is_atrous=True) x = self._batch_norm(x) x = self._relu(x) # pad when stride isn't unit x = self._conv(x, 3, out_filter // 4, 1, is_atrous=True) x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 1, out_filter, 1, is_atrous=True) if in_filter != out_filter: orig_x = self._conv(orig_x, 1, out_filter, stride, is_atrous=True) x = tf.add(x, orig_x) tf.logging.info('image after unit %s: %s', name_scope, x.get_shape()) return x def _conv(self, x, kernel_size, filters, strides, is_atrous=False): """Convolution.""" padding = 'SAME' if not is_atrous and strides > 1: pad = kernel_size - 1 pad_beg = pad // 2 pad_end = pad - pad_beg if self._data_format == 'channels_first': x = tf.pad(x, [[0, 0], [0, 0], [pad_beg, pad_end], [pad_beg, pad_end]]) else: x = tf.pad(x, [[0, 0], [pad_beg, pad_end], [pad_beg, pad_end], [0, 0]]) padding = 'VALID' return tf.layers.conv2d( inputs=x, kernel_size=kernel_size, filters=filters, strides=strides, padding=padding, use_bias=False, data_format=self._data_format) def _batch_norm(self, x): if self._data_format == 'channels_first': data_format = 'NCHW' else: data_format = 'NHWC' return tf.contrib.layers.batch_norm( x, decay=self._batch_norm_decay, center=True, scale=True, epsilon=self._batch_norm
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In this case, the insulating cover of the electrical cover is tightly secured within the recess of the first wall portion of the connecting member. On the other hand, since the width of the recess of the second wall portion is smaller than that of the recess of the first wall portion, the insulating cover is stripped when it is pressurizingly inserted into the recess of the second wall portion, so that the conductor of the electrical wire is brought into contact with the inner surface of the recess of the second wall portion to establish an electrical connection between the electrical wire and the connecting member. As a result, an electrical connection between the electrical wire and the terminal connector is established. In the conventional terminal connector as described above, however, there are disadvantages such as follows. Namely, in the conventional terminal connector, since two processes that mounts the connecting member to the terminal body and connects the electrical wire to the connecting member at the two recesses are required in order to connect the electrical wire to the terminal connector, it is difficult to improve operation efficiency for the connection. Further, in the conventional terminal connector, since the size of the electrical wire is changed, it is required to prepare different connecting members having recesses of different sizes. This means trouble in parts control of the terminal connector since each of these connecting members has bulky nature due to its structure.The measurement of products or materials in tanks or silos is important for inventory control and custody transfer in many industries. Product level monitoring is also important in filling a storage device because overfilling and spillage of potentially hazardous products must be avoided. Similarly, level monitoring can be used to detect tank leakage; e.g., large unattended oil or gasoline storage tanks must be closely monitored for possible seepage which would cause contamination of soil and ground water. Also, as the storage device is filled, the product level must be monitored to avoid overfilling and spillage of the potentially hazardous product. Large unattended oil storage tanks must be closely monitored for possible seepage which would cause contamination of the soil and ground water. The standard practice of measuring the level in a storage vessel is to lower a stick or a rope into the vessel until the product is touched. By measuring the extended length the actual level of the product or material in the tank can be determined. This is usually called "sticking the tank". A quite common example of "sticking the tank" occurs when a gasoline station attendant measures the level of a gasoline storage tank by inserting a calibrated stick into the tank and removing it to see how much of its length is wet. Such a procedure is potentially a potentially very dangerous procedure and vents the tank contents to the atmosphere, which is undesirable. Although many of the newer measuring devices which use the stick or rope concept are automated and quite accurate, such devices typically require a physical intrusion into the storage environment. Such breaching of the tank raises the possibility of the contamination of the storage vessel contents and, depending on the corrosive nature of the vessel contents, could impair or destroy the measuring device. Since the early 1970s, various level measuring devices using radar techniques have been developed to eliminate the necessity of the measuring device touching the storage vessel contents. Typical radar level measuring devices use frequency modulated continuous wave (FM-CW) signal wave forms in which the frequency of the transmitted signal is swept at a constant rate over about 1 gigahertz (GHz) around its center frequency. The reflected signal which, due to the time delay caused by the signal traveling from the transmitter to the storage vessel contents and traveling back to the receiver upon reflection from the contents' surface, will be at a different frequency than the presently transmitted signal which, during the transit time, was swept to a different frequency. The difference in frequency between the transmitted and received frequency is an indication of how far the initial transmitted signal had to travel, and thus the distance to the storage vessel contents can be determined. In such systems the minimum resolution of the measurement and the minimum measurable distance is directly related to the sweep width of the transmitted signal. Also, since the return signal is modulated by the chirp, the required detection bandwidth must be wide, decreasing the signal-to-noise ratio and thereby limiting the maximum range. The U.S. Federal Communications Commission (FCC) and international regulations limit the maximum bandwidth of the transmitted signal (at the required power levels to overcome the path loss) to 250 megahertz (MHz). Current equipment, employing fixed sweep rates and fixed sweep lengths, cannot resolve or filter out fractions of return signal cycles. These fractions of cycles occur when the sweep, which is not synchronized with the return signal, reverses or resets before a complete cycle is received. Therefore, these systems exhibit significantly lower signal-to-noise ratios and require at least a 1 GHz bandwidth. What is needed is a method and apparatus to provide an inexpensive and highly accurate measurement for the level of a product in a storage tank or silo using microwave signals given the FCC and international regulations constraint of maximum bandwidth of the transmitted signal of 250 MHz, in a system which can resolve closely spaced echoes and exhibit good signal-to-noise-ratio.Quikr!! Mumbai!! is a free local classifieds website where you can post free advertisements related a business, product and service offered in Mumbai!!. You can post free ads to buy, sell, rent or for charity in Mumbai!!. Find used cars, rent or buy apartments, find a flatmate or even start a tiffin or catering service, hobby or dance class or a fashion boutique in your locality and much more.Fluorescent protein development 1) We are studying photoswitching behaviors of photoswitchable fluorescent proteins and their use in Frster Resonance Energy Transfer (FRET) experiments. This includes an ongoing project to develop photoswitchable yellow fluorescent proteins, photoswitchable red fluorescent proteins, and far-red fluorescent proteins for use in conventional diffraction-limited microscopy as well as super-resolution molecular localization microscopy. 2) We collaborate with Joy Zhao and Peter Schuck on their development of new fluorescence ultracentrifugation techniques. We are surveying numerous fluorescent proteins to better define their oligomerization characteristics. Literature surveys have suggested these characteristics have not been rigorously determined and that unforeseen oligomerization leads to aberrant fluorescent protein behavior. 3) We have an ongoing project to develop improved red fluorescent proteins. Current variants display low fluorescence, slow maturation, and/or oligomerization. Biochemical analyses of wild type proteins coupled with site-directed mutagenesis has led to our discoveries of mRuby variants with much decreased self-association, increased brightness, and faster maturation. Cell biology projects 1) Gaetan Herbomel, a former post-doctoral fellow in the lab of Lawrence Tabak, has started work in my lab and is completing a project to image the localization of Golgi apparatus enzymes using Stimulated Emission Depletion (STED) microscopy, Multifocal Structured Illumination Microscopy (MSIM), Photoactivated Localization Microscopy (PALM), and Stochastic Optical Reconstruction Microscopy (STORM). The multi-color super-resolution experiments have required development new data analyses which we have now implemented. These studies are intended to help in our understanding of where the enzymes are located within the Golgi and what role these locations may play in the enzymatic activity. 2) We collaborate with Jim Kochenderfer (NCI) to study the self-association properties of chimeric antigen receptor (CAR) molecules using our FRET techniques. Instrumentation and imaging development 1) Frster Resonance Energy Transfer (FRET) is a powerful approach to study the interactions of fluorescent molecules. We are developing new approaches which can be performed on a conventional widefield or confocal microscope to image FRET between a donor photoswitchable fluorescent protein, Dronpa, and an acceptor based on a conventional fluorescent protein. The technique which we call photoswitching FRET (psFRET) is based on Dronpas photoswitching properties in the presence and absence of an acceptor. This technique is currently being used to monitor interactions between a number of proteins within living cells. 2) Another FRET based project using psFPs derived directly from the psFRET studies involves imaging homo-FRET by monitoring the anisotropy of the PS-FPs during the photoswitching process as a read-out of protein-protein interactions. This technique, which we called photoswitching anisotropy FRET (psAFRET), differs from measurements of hetero-FRET (energy transfer between two different color proteins) since it monitors energy transfer between copies of the same probe. 3) We are able to use a previously described coordinate-based co-localization (CBC) analysis of PALM/STORM data to develop a plugin which runs within the freely available ImageJ application. It is designed to run with one thread per computer CPU, which drastically improves the computation time. 4) We have also developed a series of image analysis macros that can be run within the ImageJ application to analyze psFRET data. To make this technique more widely useful we have developed an ImageJ plugin that is much more versatile and can be used on almost any dataset for the steps outlined above. In parallel, a second ImageJ plugin was developed to analyze the exponential decay in fluorescence at each pixel as the photoswitchable fluorescent protein switches off. These are available on the ImageJ update site (https://imagej.net/User:Pattersg). 5) We collaborate with the Hari Shroff lab on the development of improved forms of TIRF microscopy. Recent efforts by his lab have resulted in improvements to lateral super-resolution levels while maintain the acquisition speeds necessary for live cell imaging. The emphasis for our collaboration is now to improve axial resolution in this technique.<TITLE>selectionbox - Create and manipulate a selection box widget</TITLE> <H1>selectionbox - Create and manipulate a selection box widget</H1> </pre><
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2325, 1909, 53, 9167, 337, 69, 1638, 73, 380, 10566, 2051, 624, 547, 337, 69, 1384, 73, 444, 7084, 1294, 11997, 374 ]	D Ouspensky(In Search of the Miraculous), who is quoting his teacher George Gurdjieff [pictured below right]: 'Self-observation brings man to the realization of the necessity for self-change. And in observing himself a man notices that self-observation itself brings about certain changes in his inner processes, He begins to understand that self-observation is an instrument of self-change, a means of awakening. By observing himself he throws, as it were, a ray of light onto his inner processes which have hitherto worked in complete darkness. And under the influence of this light the processes themselves begin to change.' You cannot change or reform your false selves, but there is no need to do so in any event. What needs to be done is to ‘dissolve’ your false selves. The first thing to do is to understand the process(an unfortunate word, for it makes it all sound far too mechanical) of formation of the false self/selves. The next thing to do, and keep on doing, that is, practising each day and throughout each day, is self-observation---letting it (whatever it may be) be as it is in you, but being willing for it to move and change. Self-observation of your thoughts, feelings, and actions as they arise or occur---if undertaken with passive detachment and choiceless awareness (that is, with no judgment, justification, analysis, attitude, comment, interpretation, interference, criticism, or condemnation) of what unfolds as your inner and outer reality from one moment to the next---will in time break down your identification with your false selves as a result of the insight gained from the process of self-observation itself. When you truly observe the process of your thinking, and cease being ‘an observer apart from the observed’ (to use Krishnamurti’s words), which means you see the whole movement of your thoughts, and your feelings, as well as your actions, choicelessly in the sense explained above, then the very act of self-observation puts an end to thought. The result? The false selves are dissolved because they are simply the creation of thought, habits of thought, and conditioning---all of them thought. No thought, no false selves---and over time a psychological mutation occurs that is of tremendous depth and profundity. You have become a light unto yourself. Yes, it’s a wondrous thing to behold. Self-change from self-knowledge from self-observation. (Note. The reference to 'self' in the expressions 'self-change' and 'self-knowledge' is a reference to what we actually are as persons among persons. As to the expression 'self-observation,' the word 'self' has an expanded meaning as described above.) In some spiritual traditions this whole process is referred to as ‘surrender’ or ‘letting go,’ with the idea that there needs to be a re-surrender and further letting-go whenever one becomes aware of something---in particular, some false self---that is holding us back from fully being the real person that we are. It doesn’t matter what you call it. The only important thing is that you dissolve your false selves through ongoing---yes, it must be undertaken on a progressive basis---self-observation. I suggest there is no better place to begin than … now! So, start right where you are. Now. Dear Eric: Thanks, once again. I greatly appreciate your comments and best wishes. Now, all the best for those exams. If there is a 'fearful self' or an 'unconfident self' in you, or even an 'over-confident self' (it works both ways), know this---they are NOT you, the person that you (Eric) are. Do not give them power. Watch them come and go, but detach from them. The person that you are can do well for, if you have done what is appropriate, you have within you, the person, all that you need to do well. Get the picture? It is nothing other than recognizing the false as false. We need to do that in order to know, understand, and live from the true---the truth of one's being, and ground of being. Bless you, mate---and I would love to see you and your family over here Down Under one day. I would like that so very much. Ian. COPYRIGHT---TERMS OF USE---DISCLAIMER COPYRIGHT: There is no intention to infringe copyright in respect of any copyrighted material; if any person believes there is or may be an infringement of their copyrighted material on any page of this website please advise me by email and any offending material will be removed immediately. TERMS OF USE AND DISCLAIMER: By and in using this blog, which includes but is not limited to all posts as well as all material linked to those posts as well as to any other parts of the blog ("this Site"), the user agrees to the following Terms of Use and Disclaimer: The purpose of this Site is to give information by way of general comment only, which is not designed to be comprehensive, but which may be of interest to some or all of the public ("the Information"). 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now, but the people holding her simply grabbed her legs and arms and held on. Something hissed against her arm and she thought snake before passing out. Not a snake, she thought when she woke up. The angel and a woman in strange clothes sat beside her bed. The woman said, "I know you're not going to believe this either, but you're in an archival facility in the future. Think of it as a library for people. I'm here to explain your legal standing in our culture." Benedetta wondered how many layers of lies they'd try on her. The fake angel said, "We're trying to learn about the past and we'd like you to help us." The woman said, "We saved your life and brought you into the future. A lot of people are more comfortable if they think they died and are in an afterlife they can understand." Maybe they aren't lying? Benedetta thought this was all too crazy for anyone to try as a lie. Should she pretend to believe it until she could learn more, or just stay confused? "We're sorry, but I don't understand why you bit me," the angel said. "Why so hard?" "You were lying to me. Well, thank you for saving me from dying. I can't believe those French. I want out of here." "We'd like to spare you the culture shock," the woman said. Benedetta didn't know how culture could cause shock. "We've saved your life," the man said. "Not that we expect you to be immediately grateful, or to believe us. Yet. But can you begin to tell us honestly about your life. We really want to know what you saw, how you lived, what your customs were." "I want to see the future first," Benedetta said. Her heart was beating very fast. "You have the right to be treated as reasonably as possible. But I think you should wait," the man said. "Your heart is beating very rapidly." I've been trapped by magicians, Benedetta thought. "I couldn't believe in Purgatory." "Most people from the period of Christianity that had a concept of Purgatory as well as Heaven and Hell would find Purgatory believable. Nobody believes they are good enough for heaven—or at least they don't argue about it. And people are relieved to find they're not in Hell," the man said. "I'm Joseph. You can call me Joe." "But she isn't sure where she is now, are you?" the woman said. "In a camera obscura," Benedetta answered. "Well, sort of," Joe said. "You probably want to get some rest and think about things for a while. All your friends are dead, in the past. If you believe us, this has to be a shock." "What is the year?" Benedetta asked. "By the Christian calendar, 2308," the woman said. "Eight hundred and fucking nine years from 1499," Benedetta said. Benedetta realized she didn't know how to get out of their archival room. What was the difference, 1499 or 2308? They were men and women, like other men and women. She would have to get to know them, then figure out who would bend the rules for her. Until then, she'd tell them as many stories as they'd believe. Joe asked, "You can do subtraction in your head?" He sounded genuinely amazed. "Yeah, I can do subtraction in my head. You think I'm stupid because I'm a peasant girl?" "We would never have thought that," Joe said. "It's that we didn't know women were taught to figure in your time." "Oh," Benedetta said. She decided not to tell them she could read, too. Raped, kicked, and left dying, she'd been brought to some fake purgatory run by creeps who'd out-clevered the Florentines with their toys of light. Purgatory wouldn't have been a good fit. Hell was where Benedetta had expected to find herself on the days when she bothered to believe in an afterlife. Most of the time, she figured dead was dead, so up in the future could be better yet. Living in the future, if she could escape the forgeries of times past in these little rooms, would be another adventure. "I want to see this future." "Your immune system can't handle current diseases. Even immunizations to prevent the diseases might kill you. We can't let you out that easily," Joe said. "Explain that in words I know." "Eight hundred years years isn't genetically that large a spread," the woman said, then spoke further in a strange language. "Look, I'm not stupid. Explain what an immune system is." Benedetta spoke the words as well as she could remember them. The future people seemed surprised for some reason. "I can't explain without you knowing more of our language. We have medicines to prevent diseases, for most of the deadly modern diseases. These are not without risks and while you can ask for them, you need to understand what the risks are. And it's hard to explain any of this in archaic Italian." I'm in prison, with better food, with people to talk to, and without beatings, but it's still prison. "So teach me your language if that will help me understand better." "What was it like being with the army?" Joe asked. "You were a camp follower, right?" "No, I wasn't a common camp woman; I was on the artillery team with my husband." She'd never married Emelio in the church, but they'd been together long enough. The people who'd saved and imprisoned her had another hasty conversation in their language, then Joe said, "Okay, we've suspected that the future could send people into the past just as we can move them out, so that is a possibility here, but there are accounts of women working on gun crews in Burgundy." Benedetta shrugged. These people saved her life, but they weren't interested in setting her free. She wondered what they'd do if she lied and said she was from the future. No, she'd tell them the truth until she had a better idea of what sort of mess she was in. Joe asked, "Where in Italy did you travel? What did you see? We're interested in learning things about how people lived that didn't get mentioned in the written records." "We lived in Milan when we weren't on jobs." They talked among themselves. "Really. Can you show us on a map?" They brought in a map of the streets of Milan, some different than what she'd remembered, and it didn't look like the map Leonardo drew. She found the old Sforza castle where Leonardo had lived, and found the little house near it, and said, "Some years, we lived there. And we visited one of the duke's engineers there a lot." She pointed to the old castle. The future people went nuts for a while in that strange language they were speaking. "Are you talking about meeting Leonardo di Vinci?" Yeah, I'm really from the past; I was really on an artillery crew; Leonardo really tried to seduce Emelio but thought I looked nice in mountain-girl clothes. Benedetta finally said, "Milan didn't have that many first-class artillery crews, and Emelio was cute as well as bright. We spent a lot of time at Leonardo's place. He even borrowed my kid for one of his experiments." "I know someone who'd have so many questions for you," Joe said. "Normally, the people we get didn't know anyone historically significant in the old sense of historically significant." "I will tell you what I know if I can get out of here." Joe said, "Did you use forks for eating at the table and for what and what did they look like? Yeah, the information on Leonardo will excite some people, but what I'm most interested in is the daily life of the past, what wasn't in books." Benedetta remembered how weird forks has seemed when she first saw them at the table. "Saved on water, having your own fork to hold meat. And on fingers eating sticky things." She wouldn't tell them how embarrassed she'd been not knowing how to use a fork when she first saw one. But they were excited that she'd met Leonardo. Um, something to work with there. Man's reputation lasted more than eight hundred years; Leonardo wouldn't have been surprised, though. "If you see the future, it may corrupt what you remember of the past," the woman said. "Did Leonardo's drawing books get passed up to the future?" Benedetta asked. They chattered between themselves again, then said, "Yes, some of them." "What is this culture shock you mentioned?" "Most people from the past would have mental difficulties if they tried to understand our times. Most of the more modern ones, and some of the most archaic ones, finally learn where and when they're living now," Joe said. "They're happiest living in places that most resemble their own times. We try to keep them comfortable." But they don't live long was generally the rest of that statement in Bened
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1514, 295, 1080, 74, 1215, 11, 8506, 22, 2526, 1717, 3031, 3424, 63, 66, 63, 9873, 29078, 1180, 275, 253, 18379, 5447, 273, 47222, 16616, 3614, 1358, 2700, 15, 35301, 15, 35510, 15, 24645, 15, 12312, 16, 3023, 550, 410, 4357, 481, 63, 67, 4526, 575, 395, 575, 3424, 575, 527, 9038, 326, 24402, 41064, 14, 3022, 30448, 3275, 310 ]	to produce a variety of compounds with divergent chemical structures^[@CR3]^. Recently, the C~30~ and C~50~ biosynthetic pathways were found in Micrococcus, Corynebacterium, and Flavobacterium^[@CR4]^. Carotenoids can function as photoprotectors, light harvesting molecules, or membrane stabilizers^[@CR5]^. In non-phototrophic bacteria, the main function of carotenoids is the protection of cells from photo-oxidative damage by scavenging harmful agents such as singlet and triplet molecular species produced upon illumination^[@CR1],[@CR6]^. In non-phototrophic bacteria, the control of carotenoid production is classified into three types: constitutive, light-inducible, and cryptic manner^[@CR7]^. We and other groups have been studying the phenomena and molecular mechanism of light-inducible production of carotenoids of phylogenetically different bacteria including S. coelicolor A3(2)^[@CR8]^, Thermus thermophilus HB27^[@CR9]--[@CR14]^, Bacillus megaterium QM B1551^[@CR15],[@CR16]^, Mycobacterium marinum^[@CR17]^, and Arthrobacter arilaitensis^[@CR18]^. Our study has revealed that LitR/CarH family proteins, a MerR family transcriptional regulator retained by S. coelicolor, T. thermophilus, and B. megaterium, play a central role in light-dependent gene expression^[@CR19]^. Other groups have also reported that LitR/CarH family proteins serve as a photosensor in the light-inducible production of carotenoids in Myxococcus xanthus^[@CR20],[@CR21]^. LitR/CarH family proteins commonly contain a DNA-binding domain in its N-terminus and an adenosyl-coenzyme B~12~ (AdoB~12~)-binding domain in its C-terminus, and serves as a negative regulator for light-inducible transcription^[@CR13],[@CR19]^. The molecular mechanism of light-inducible transcription mediated by the LitR/CarH family involves the photolysis of AdoB~12~ associated with LitR/CarH due to light, which results in a large conformational change and inactivation of the DNA-binding activity of LitR/CarH^[@CR11]^. LitR homologs are widely distributed in the phylogenetically diverged genera of non-phototrophic bacteria, including gram-negative and gram-positive bacteria, which indicate that LitR/CarH family proteins are general photosensors and have diverse roles in non-phototrophic bacteria. Recently, we have also reported the existence of a novel type of LitR/CarH family proteins in Burkholderia multivorans belonging to Beta-proteobacteria, which requires a different type chromophore from coenzyme B~12~^[@CR22]^. The wide distribution of LitR/CarH family protein among non-phototrophic bacteria leads to our assumption that other type of light-inducible transcriptional regulators is present in non-phototrophic bacteria. The finding of a novel type of photosensors would deepen insights on bacterial environmental responses. In this study, we performed a wide screen of bacteria exhibiting light-inducible production of carotenoids, which led us to the finding that some groups of gram-positive bacteria including C. glutamicum, an amino acid producer, exhibit photo-dependent production of carotenoids. The evidence indicates that a light-induced MarR family regulator CrtR, is distributed to some groups of Actinobacteria and is involved in the light-inducible expression of crt biosynthesis genes. Results {#Sec2} ======= Light-inducible yellow-color pigment production in bacteria belonging to the order Micrococcales {#Sec3} -------------------------------------------------------------------------------------------------- We previously reported that a number of Bacillus spp. isolated from soil showed light-dependent production of carotenoid on rich LB medium^[@CR15]^. Our genetic and biochemical study of B. megaterium QM B1551 revealed that LitR in complex with B~12~ serves as a photosensitive transcriptional regulator to control the expression of crt biosynthesis genes in a light-dependent manner. Here, we used several media including not only LB but also 10-fold diluted LB medium (1/10 LB), 1/10 LB containing 1% glucose (1/10 LBG), and R2A medium to more widely screen bacteria exhibiting light-inducible yellow-color pigment production (see Materials and Methods). We isolated a number of bacteria from various environmental source including biotope, paddy field, forest soil, bran pickled, snow, residential land, and cattle manure in Japan. Of these, bacteria showing white light-dependent pigment production were subjected to the phylogenetic analysis based on DNA sequence of the 16S rRNA gene. As summarized in Table [1](#Tab1){ref-type="table"}, a total of 24 strains out of approximately 1,100 isolates exhibited light-inducible yellow-colored pigment production. The number of the isolated photo-responsive bacteria was 1 strain out of 121 (0.8%) with LB medium, 7 out of 526 (1.3%) with 1/10 LB medium, 14 out of 361 (3.9%) with 1/10 LBG medium, and 2 out of 92 (2.2%) with R2A medium. The isolates mainly belonged to the order Micrococcales, a high G + C gram-positive Actinobacteria, including the genus Arthrobacter, Leifsonia, Microbacterium, Brevibacterium, and Agromyces. As minor groups, Bacillus, Sphingobacterium, and Simplicispira genus were also isolated. All isolates exhibited \>99% sequence identity with the known species affiliating to those bacterial taxa. This result indicated that 1/10 LB and 1/10 LBG medium were suitable for the isolation of photo-responsive Micrococcales bacteria.Table 1Phylogenetic characteristics of isolates based on the 16S rRNA gene sequence.Isolates No.Source of isolation (Locality of source)Isolation mediaClosest taxonClosest GeneBank relativeResponse to light^b^Genus/SpeciesOrderAccession No^a^Similarity (%)16Biotope (Kanagawa pref.)LBBacillus megateriumBacillalesAY03033899+199Paddy field (Ibaraki pref.)1/10 LBBacillus megateriumEU88050699+295Forest soil (Kanagawa pref.)1/10 LBAgromyces ulmiMicrococcalesAY42783098++2961/10 LBBacillus subtilisBacillalesFJ48351499++423Bran pickled (Kanagawa pref.)R2ABrevibacterium linensMicrococcalesDQ36101698++459Snow (Yamanashi pref.)1/10 LBGSphingobacterium siyangenseSphingobacterialesEU64627299++496Soil of residential land (Chiba pref.)1/10 LBGPaeniglutamicibacter sulfureusMicrococcalesAB04635899++5041/10 LBGPaeniglutamicibacter sulfureusX8340999++5141/10 LBGPaeniglutamicibacter sulfureusEF15424599++5161/10 LBGMicrobacterium phyllosphaeraeAJ277840100+5261/10 LBGMicrobacterium foliorumEU714341100+5271/10 LBGPaeniglutamicibacter sulfureusAB04635899++5501/10 LBGPaeniglutamicibacter sulfureusX8340999++647R2APaenibacillus alveiBacillalesAB37710899+732Biotope (Hokkaido)1/10 LBLeifsonia shinshuensisMicrococcalesDQ23261499++742Paddy field (Ibaraki pref.)1/10 LBSinomonas atrocyaneaX8074699++905Cattle manure (Iwate pref.)1/10 LBGlutamicibacter arilaitensisEU83426099++9191/10 LBSimplicispira metamorphaBurkholderialesY1861896+9431/10 LBGGlutamicibacter nicotianaeMicrococcalesEU85742099++9511/10 LBGPaenarthrobacter nicotinovoransAB36393399+10311/10 LBGSimplicispira metamorphaBurkholderialesY1861896+10391/10 LBGMicrobacterium natorienseMicrococcalesAY56629199++10521/10 LBGMicrobacterium natorienseAY56629198++10771/10 LBGMicrobacterium natorienseAY56629199++^a^Corresponding number in the nucleotide database of NCBI (<https://www.ncbi.nlm.nih.gov/nuccore/>).^b^+ and ++ indicate that carotenoid-like pigment production is
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1638, 1235, 10, 310, 1534, 15, 733, 310, 2668, 432, 253, 17502, 443, 1017, 27, 795, 284, 344, 497, 247, 4195, 1321, 466, 4414, 1292, 436, 443, 1017, 858, 417 ]	the still, warm evening and sent so many leaves pattering down that we thought it was raining. We all held our breath, the other two appreciating the ecstasy of such a thing almost as you would.' In a subsequent letter to Greeves (18 October 1931) Lewis recounted the ideas proposed by Dyson and my father in respect of the 'true myth' of the story of Christ; and both in his _Biography_ and more fully in _The Inklings_ (Allen & Unwin, 1978, pp. 42-5) Humphrey Carpenter has imagined the discussion of that night, drawing from Lewis's letters and from the tenor of the argument of _Mythopoeia_. The second marginal note to the final text can be conveniently given here, though it is explanatory and does not bear on the history of the poem. The reference is to the eighth line of the ninth verse ( _bogus seduction of the twice-seduced_ ): ' _Twice-seduced_ , since to return to earthly well-being as a _sole_ end is one seduction, but even this end is mis-sought and depraved.' At the same time as these notes, my father wrote at the end of the manuscript: 'Written mainly in the Examination Schools during Invigilation.' The text of _Mythopoeia_ printed here is that of the final version exactly as it stands in the manuscript. Though the textual history is complex in detail, it can be said that the development of the poem through seven versions was largely a matter of extension. In the earlier forms it was much shorter, lacking the three verses beginning _Blessed are_ , and ending with the line _nor cast my own small golden sceptre down_. CHRISTOPHER TOLKIEN ## ON FAIRY-STORIES I propose to speak about fairy-stories, though I am aware that this is a rash adventure. Faërie is a perilous land, and in it are pitfalls for the unwary and dungeons for the overbold. And overbold I may be accounted, for though I have been a lover of fairy-stories since I learned to read, and have at times thought about them, I have not studied them professionally. I have been hardly more than a wandering explorer (or trespasser) in the land, full of wonder but not of information. The realm of fairy-story is wide and deep and high and filled with many things: all manner of beasts and birds are found there; shoreless seas and stars uncounted; beauty that is an enchantment, and an ever-present peril; both joy and sorrow as sharp as swords. In that realm a man may, perhaps, count himself fortunate to have wandered, but its very richness and strangeness tie the tongue of a traveller who would report them. And while he is there it is dangerous for him to ask too many questions, lest the gates should be shut and the keys be lost. There are, however, some questions that one who is to speak about fairy-stories must expect to answer, or attempt to answer, whatever the folk of Faërie may think of his impertinence. For instance: What are fairy-stories? What is their origin? What is the use of them? I will try to give answers to these questions, or such hints of answers to them as I have gleaned – primarily from the stories themselves, the few of all their multitude that I know. ## FAIRY-STORY What is a fairy-story? In this case you will turn to the _Oxford English Dictionary_ in vain. It contains no reference to the combination _fairy-story_ , and is unhelpful on the subject of _fairies_ generally. In the Supplement, _fairy-tale_ is recorded since the year 1750, and its leading sense is said to be ( _a_ ) a tale about fairies, or generally a fairy legend; with developed senses, ( _b_ ) an unreal or incredible story, and ( _c_ ) a falsehood. The last two senses would obviously make my topic hopelessly vast. But the first sense is too narrow. Not too narrow for an essay; it is wide enough for many books, but too narrow to cover actual usage. Especially so, if we accept the lexicographer's definition of _fairies_ : 'supernatural beings of diminutive size, in popular belief supposed to possess magical powers and to have great influence for good or evil over the affairs of man'. _Supernatural_ is a dangerous and difficult word in any of its senses, looser or stricter. But to fairies it can hardly be applied, unless _super_ is taken merely as a superlative prefix. For it is man who is, in contrast to fairies, supernatural (and often of diminutive stature); whereas they are natural, far more natural than he. Such is their doom. The road to fairyland is not the road to Heaven; nor even to Hell, I believe, though some have held that it may lead thither indirectly by the Devil's tithe. O see ye not yon narrow road So thick beset wi' thorns and briers? That is the path of Righteousness, Though after it but few inquires. And see ye not yon braid, braid road That lies across the lily leven? That is the path of Wickedness, Though some call it the Road to Heaven. And see ye not yon bonny road That winds about yon fernie brae? That is the road to fair Elfland, Where thou and I this night maun gae. As for _diminutive size_ : I do not deny that that notion is a leading one in modern use. I have often thought that it would be interesting to try to find out how that has come to be so; but my knowledge is not sufficient for a certain answer. Of old there were indeed some inhabitants of Faërie that were small (though hardly diminutive), but smallness was not characteristic of that people as a whole. The diminutive being, elf or fairy, is (I guess) in England largely a sophisticated product of literary fancy. It is perhaps not unnatural that in England, the land where the love of the delicate and fine has often reappeared in art, fancy should in this matter turn towards the dainty and diminutive, as in France it went to court and put on powder and diamonds. Yet I suspect that this flower-and-butterfly minuteness was also a product of 'rationalisation', which transformed the glamour of Elfland into mere finesse, and invisibility into a fragility that could hide in a cowslip or shrink behind a blade of grass. It seems to become fashionable soon after the great voyages had begun to make the world seem too narrow to hold both men and elves; when the magic land of Hy Breasail in the West had become the mere Brazils, the land of red-dye-wood. In any case it was largely a literary business in which William Shakespeare and Michael Drayton played a part. Drayton's _Nymphidia_ is one ancestor of that long line of flower-fairies and fluttering sprites with antennae that I so disliked as a child, and which my children in their turn detested. Andrew Lang had similar feelings. In the preface to the _Lilac Fairy Book_ he refers to the tales of tiresome contemporary authors: 'they always begin with a little boy or girl who goes out and meets the fairies of polyanthuses and gardenias and appleblossom... These fairies try to be funny and fail; or they try to preach and succeed.' But the business began, as I have said, long before the nineteenth century, and long ago achieved tiresomeness, certainly the tiresomeness of trying to be funny and failing. Drayton's _Nymphidia_ is, considered as a fairy-story (a story about fairies), one of the worst ever written. The palace of Oberon has walls of spider's legs, And windows of the eyes of cats, And for the roof, instead of slats, Is covered with the wings of bats. The knight Pigwiggen rides on a frisky earwig, and sends his love, Queen Mab, a bracelet of emmets' eyes, making an assignation in a cowslip-flower. But the tale that is told amid all this prettiness is a dull story of intrigue and sly go-betweens; the gallant knight and angry husband fall into the mire, and their wrath is stilled by a draught of the waters of Lethe. It would have been better if Lethe had swallowed the whole affair. Oberon, Mab, and Pigwiggen may be diminutive elves or fairies, as Arthur, Guinevere, and Lancelot are not; but the good and evil story of Arthur's court is a 'fairy-story' rather than this tale of Oberon. _Fairy_ , as a noun more or less equivalent to _elf_ , is a relatively modern word, hardly used until the Tudor period. The first quotation in the _Oxford Dictionary_ (the only one before AD 1450) is significant. It is taken from the poet Gower: _as he were a faierie_. But this Gower did not
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Because of this Aron has hundreds of satisfied clients. Many of which return years later for a portrait of the next generation of their pets. Your picture will be on your wall for many years, so it pays to ensure it is a fitting reminder of your animal. In fact some families club together to commission a pet portrait for a special birthday or anniversary. For more information about Aron's pet portraits please click on the Artist button, or to see more examples of previous commissions, enter the galleries by clicking on one of the gallery buttons above. Aron provides a complete pet portrait service, from photo-shoot to framing, and although based in Andover, Hampshire, (which is near the borders of Berkshire and Wiltshire,) routinely receives commissions for his animal portraits from all over the South of England, especially Sussex and Surrey. He also travels to Yorkshire a couple of times a year and can do photoshoots anywhere in-between. In this way he can cover most parts of the UK.Welcome to the PokéCommunity! Hi there! Thanks for visiting PokéCommunity. We’re a group of Pokémon fans dedicated to providing the best place on the Internet for discussing ideas and sharing fan-made content. Welcome! We’re glad you’re here. In order to join our community we need you to create an account with us. Doing so will allow you to make posts, submit and view fan art and fan fiction, download fan-made games, and much more. It’s quick and easy; just click here and follow the instructions. Pokémon Sun and Moon are now available! Read our extensive Sun and Moon review at Daily! The finale of the fourth annual Favorite Pokémon Tournament is underway in Pokémon General!View the poll and vote for as many Pokémon as you'd like. Voting is only open until the 5th of December though, so don't wait to make your picks! I've never been in a relationship like the one you're in now, and I won't pretend and say I know how you feel, cause I don't. I just don't want to see you get hurt. Every time I see you come run to me and cry over the past mistakes your boyfriend made, it makes me feel so sorry for you. But you have to realize that at this point, it's your stubbornness that's making your life a living hell. He changed for the better. Sure, it took a few mistakes, but you say that he did, and I believe that. I only met the dude once, but he seems alright. To be so caught up in the past, though, isn't healthy. I told you that at this point you had two options, either forget the past, or break up with him. The way I see it, it doesn't matter how much you love him, if being with him hurts you so much (cause this has been happening for a while now) then it just isn't worth it. And yeah, I know it's easier said than done. But like I said, I don't want to see you get hurt. Please, for your sake, do something. You used to be a really great friend until you started acting all weird and drifted off. You ignoring me got on my nerves to the point where I started ignoring you too. I'm already trying my best to patch things up so I do hope you are putting in some effort too! I hope all goes well soon. I miss you, my friend. I've been meaning to text you and ask if we could chill anytime soon, especially since you live up the road from me. We both said to each other that we should hang over the summer before we graduated, but we have yet to do that. It's been a month since I've seen you, so please at least remember who I am if I text you and ask you if we could hang in the near future. Thank you so much for the times we had together but I wish you would come home. I know that you have a life now and your priorities are first, but I havent seen you in months and just I want to know that our graduation wasnt the last time I'll ever get to see you. Please visit me soon dude. Oh god, you're making things so awkward. I don't know if your texts are unintentionally making me feel uncomfortable, or if you're slyly making me feel guilty over what I did. If it's the latter, you're doing a good job. I said I couldn't do it, and I had my reasons. I said I'm sorry. What more do you want from me? I was scared to message you at first about this, but I'm thankful now that we will be seeing each other again soon. I can't wait for you to come over and hang out with me for a few hours. See you soon! You should learn to follow your own advice. It's getting a little tiresome. da, It was nice seeing you after you came to the city. I'm even surprised that you picked me out of every other person there. Hopefully you come back here soon, and perhaps we can take a day to hang out, or perhaps I can give you my number so we can text each other. da, I really miss you and I want to text you again. I can't wait for August. Get back sooner. da, I think you're really cute, but I don't think we could hit it off in a million years. The end of July is coming, regardless of how slow it is. When you come up, we have to make as much of the time as we can get. Because who knows when you'll be up after that. We do have skype, but I'd rather actually hang out with someone rather than talk with them on a screen for 25 or 30 minutes. Things really didn't go as how I expected it. The first day of school it was okay and you were really friendly and I liked that. But the very next day you started it all over again. You used my stationery, drew on my papers and invaded a large portion of my table space, all without asking. Really, I would have let you do so if you just asked. Don't just assume that I'm fine with everything because I don't seem to show any disapproval. I have feelings too. And the only reason I don't stop you from doing all these is because it isn't in my character to do so and I'd probably hurt your feelings if I told you. I do know that you're feeling very lonely in class despite being surrounded by so many classmates I can't help you if this continues. I sincerely hope things head towards the better. And like what the teacher told us, 'Our feelings can connect with the heart but the mind has to work on it's own to set things right', or in other words, think before you act based on your emotions. I'll be trying my best to do this so let's work hard together! So I have a lot of wasted intellect and a lot of spare time on my hands, I can assure you they were entirely coincidental and I want to apologise if I made you uncomfortable or offended you in any way. I'll drop it when you drop it. Dear Anonymous, I seemed to have forgotten about you for a while but here you are again. Back in my news feed. I always did think you were cute, ever since E was stalking your photos and I was silently observing. You have no idea how cranky she got afterwards, so jealous. I know we've never met in person but I really want to get to know you, both E and D tell me about how kind and fun you are. I can't just say hi over the internet because we both know that any chump with a keyboard can do that, I want to do it right, besides I've tried that before and nothing comes of it. I know your time being single is running out, we should be introduced. It could be good. I am so glad you are doing better this week as I know last week was a mess for all of us D:. I thought when you were having thoughts of giving up, I'd lose another person close to me, but with you now looking at the bright side of the future everything seems good and well. You are such a bad influence, but I love you <3 I wish we were still friends, but we have grown and moved a part. I still like hearing the stories about how bad you truly are, even though I know you mean well. Talking about anime like nothing happened isn't really doing me any favors. I know you know that. I'm sorry I'm a pain in the ass to deal with but I can't help it. Please just understand. Leave me alone for awhile... but, then again, I don't think I can stand to not talk to you any more than I already have. I miss you more and more each day. I know you're having a fun time, but I... I just miss what we used to be. I can't wish you back any more, because it'll just be wasted effort. It's not your fault; it's mine. I just wish I could've been a better boyfriend. I'm sorry. Dear anonymous... I'm sorry. I really don't want to mess anything up with your new love, but... just remember I'm still here, okay? I don't see what's the big deal with me doing events on forums. Really have you never
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253, 5810, 278, 1000, 1031, 7063, 1475, 616, 8576, 2829, 1051, 891, 871, 1051, 309, 12491, 436, 374, 2607, 3622, 281, 452, 247, 2159, 281, 755, 952, 715, 19152, 3996, 15, 380, 4736, 369, 281, 452, 247, 2159, 17478, 275 ]	weak Outcome statements, with suggestions on how they can be improved. Examples of strong and weak Outcome statements Results Reporting Format The Guide provides a useful new format for results reporting. In the past different projects have reported in a wide variety of ways, often forcing readers to wade through dozens of pages of descriptions of activities, in a vain attempt to find out what the results are. This suggested new format puts results up front, in a table, emphasizing indicator data, with room for explanations in text, below. These and other additional tips can be found in section 3 – Step by Step Instructions on results-based project planning and design (p. 66-85) and section 4 – Managing for Results during Implementation (p. 86-92) but others are spread throughout the document, and for that reason it is useful to read the whole document, even if users are familiar with past CIDA/GAC documents. Limitations This is a good, practical RBM guide, but having a good guide is one thing, and getting people to use it – or to deal with the implications of what it means for agency operation, is another. I see two areas where further improvements could be made, some of which could be done informally, and some which, given procedures in the Government of Canada, are perhaps beyond the scope of the GAC RBM group’s control. 1. Dealing with the Implications of RBM for operations and funding I have seen very small civil society organizations face lengthy processes of data collection and report revisions, to comply with donor agency RBM requirements for relatively inexpensive projects. But at the same time donor agencies themselves - and this means most donors - often do not deal realistically with the implications of their own guidelines for project budgets. Baseline data Take baseline data collection, for example. The GAC Guide sections on Indicators and the Performance Measurement Framework (p. 52-64) are generally quite practical, and make the very valid point that baseline data for indicators must be collected before targets can be established, and results reported on. I agree completely that this is the most useful way to proceed – if the time and budget are allocated to make it possible. As the GAC guide says about baseline data (I have added emphasis): "When should it be collected? Baseline data should be collected before project implementation. Ideally, this would be undertaken during project design. However, if this is not possible, baseline data must be collected as part of the inception stage of project implementationin order to ensure that the data collected corresponds to the situation at the start of the project, not later. The inception stage is the period immediately following the signature of the agreement, and before the submission of the Project Implementation Plan (or equivalent). "[p. 60] In a rational process this would in fact be the situation. But the reality is that for projects funded by GAC and many other donors, after two or three years of project design and approval processes, both the donor and the partners in the field want to start actual operations quickly. The amount of time allocated by donors and partners for the inception field trips by implementing agencies – and the budget allocated to support baseline data collection processes - are too limited to make baseline data collection for all indicators during the inception period feasible in all but the most unusual cases. A typical inception field trip for an inception period might last 3-4 weeks, rarely longer, and during this period a theory of change process has to be initiated with all of the major stakeholders, an existing logic model tested and perhaps revised, a detailed work breakdown structure, and risk framework developed, institutional cooperation agreements negotiated, and detailed discussions on a Performance Measurement Framework with a multitude of potential stakeholders completed. As the GAC guide notes: "As with the logic model, the performance measurement framework should be developed and/or assessed in a participatory fashion with the inclusion of local partners, intermediaries, beneficiaries and other stakeholders, and relevant Global Affairs Canada staff." [p. 58] Some of these indicator discussions alone, where an initial orientation is required, and where there are multiple stakeholders, with different perspectives and different areas of expertise involved, can take 20 or 30 professional staff one or even two weeks in full time sessions, to reach initial agreement on what are sometimes 30 or 40 indicators. In some cases baseline data are available immediately, and that is one important criterion in choosing between what may be equally valid indicators. But in many cases, the data collection must be assigned to the partner agencies in the field, who know where the information is, and how to get it. All of this means that a second round of discussions must be undertaken, to discard those indicators for which baseline data are unavailable, or just too difficult to collect and agree on new indicators. And, as the GAC guide quite correctly notes: "The process of identifying and formulating indicators may lead you to adjust your outcome and output statements. Ensure any changes made to these statements in the performance measurement framework are reflected in the logic model." [p. 81] The partners, meanwhile, have their existing work to continue with – and rarely see the baseline data collection as their most important operational priority given the political and institutional realities they fact to do their normal work. I have participated in several design and inception missions, and I cannot remember when baseline data for all indicators were actually collected before the project commenced. And at mid-term in many projects it is not unusual for an audit of the indicators by a monitor to find that 30-40% of the indicators may not have baseline data, even after two or three years of project operation. All of this could be avoided if more money and more time – up to six months perhaps – were allocated to the inception period, with an emphasis on establishing a workable monitoring and evaluation structure, and actually funding baseline data collection. That means that when a donor agency emphasizes participatory development of indicators, during an inception period, it should be prepared to provide the resources of time and money necessary to make this practical. 2. Limiting the Logic Model to three levels The GAC logic model has three results levels - for short-term, medium term and very long term changes. This is about standard for most agencies. But, of course, only two of these levels are actually operational, and susceptible to direct intervention during the life of the project – Immediate Outcomes in the short term (1-3 years on a 5 year project) and Intermediate Outcomes which should be achieved by the end of the project. The Ultimate Outcome level is the result to which the project, along with a host of other external agencies, including the national government, and other donors, may be contributing. In real life, a Logic Model which actually reflects the series of interventions, from changes in understanding, which are necessary for a change in attitudes, to changes in decisions or policies and changes in behaviour or professional practice, will go through a minimum of 4 to 5 or even more stages where needs assessments, and training of trainers or researchers lie at the beginning of the process, before we get to field implementation of new policies or innovations. I have worked with partners in the field during project design where during the theory of change analysis, up to 8 different levels were identified, with assumptions, interventions and purported cause and effect links between these levels, before ever getting to the ultimate long-term result. It is impractical, the donors would argue, to have even a 5 level Logic Model – and this would indeed require extra work on indicators. But while the Global Affairs RBM guide does give a nod, on page 48, to the idea of “nested logic models” something I have worked on with partners, these can be more complicated to present and to understand than a 4 or 5-layer Logic Model. Some partners have decided to maintain their own more detailed, multi-level logic models, and present a simplified version to the donors, because the whole purpose of these tools is not primarily for reporting to donors – but to help managers determine what interventions are working, and what changes are needed. That is why the process is called Results-Based Management, and not just results based reporting. Having produced a more detailed and informal Logic Model, these partners, when an evaluator, a Minister, or a new donor representative has difficulty seeing how a simple two layer Logic Model can actually attribute results to interventions, can produce the real Logic Model and explain the relationships. It is unlikely that any donor will agree to a 4 or 5-level Logic Model, but it would be useful, as this Guide will be revised, to include a section illustrating the process of nesting Logic Models. The Bottom Line This new Global Affairs Canada Results-Based Management guide is an absolutely necessary tool and reference for anyone working on Canadian aid projects – and it is a practical, very useful resource for anyone who wants clarity on the process of results-based project design. I will keep the old 2001 PIP Guide on hand, however, for its still useful detail, and user-friendly format, as a complement to the new RBM guide. Greg Armstrong is a Results-Based Management specialist who focuses on the use of clear language in RBM training, and in the creation of usable planning, monitoring and reporting frameworks. For links to more Results-Based Management Handbooks and Guides, go to the RBM Training website. About Me Greg Armstrong brings what we know about how adults learn to helping international development workers use Results-Based Management in their work. If it is done right, it can be enjoyable, and productive, helping us explain our work to others.Yeah. the current story does NOT have the characters merrily sitting around their kitchen table... i know... I drew this 2 months ago to have a short to get people into twistEd. The goal was to have a short comic in
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3016, 14, 49571, 14, 39683, 18541, 10689, 187, 9, 4708, 45, 1450, 46, 4641, 24227, 14, 13152, 4625, 49, 14, 32847, 20982, 187, 313, 37155, 577, 187, 50272, 20805, 1848, 25444, 9233, 45, 1450, 24227, 14, 24906, 14, 46, 14, 10311, 14, 34, 14, 35649, 48160, 1228, 187, 313, 27267, 608, 187, 50272, 20805, 1848, 25444, 9233, 45, 1450, 1848, 9482, 25876, 14, 6603, 29244, 11477, 14, 5915, 38, 7864, 14, 29, 1228, 187, 313, 19490, 577 ]	gets expensive very quickly just from the standpoint of shipping and insurance. It never hurts, though, to call the nearest Canon service center and get an estimate. Also check with your courier of choice to see how much it will cost to ship and insure your camera to the service center. Although Canon does not officially consider the focus screen of the Rebel T3i/600D user replaceable, the method to remove/replace the focusing screen is very similar to models that are considered as such by Canon. If you choose to try it yourself please do so at your own risk! You must accept full responsibility for whatever happens to your camera. We accept no liability for any damage resulting from your choice to use the instructions linked below. Should damage occur as a result of following these instructions you accept full responsibility for the cost of any servicing, repair, or correction needed. Here are the instructions from katzeye optics for removing/replacing the focusing screen of the 600D. Please also be aware that even after successfully removing the focusing screen, it may or may not be possible to clean the residue of the dead bug from the screen without damaging the delicate surface of the screen. Some Canon camera models do have focusing screens officially considered user replaceable while others do not. Many of the higher end models that do not support user replaceable focusing screens include LCD overlays for displaying information in the viewfinder. The early models with the LCD overlays (7D, 5D Mark III, 70D) do not support user replaceable focusing screens. Due to the presence of the LCD overlay the removal/replacement of a focusing screen on those models is even more involved and delicate that that of your 600D. The newer 7D Mark II and 6D include an LCD overlay but also have focusing screens considered user replaceable and several alternate focusing screen options are available from Canon. None of the Rebel/xx0D/xxx0D series or the x0D series prior to the 50D officially support user replaceable screens either. Some of the newer models in those series may also include an LCD overlay. Here's a list from Canon as of 11/04/2015 that includes which cameras have officially user replaceable focusing screens and which replacement screens are compatible with which models. (The newest Canon models, the EOS 5Ds and EOS 5Ds R, are not listed on the 11/04/2015 version of the list) https://support.usa.canon.com/kb/index?page=content&id=ART143832 Contact Us For Customer Support Direct mail correspondence to: Your Hospital Bill It is important to remember that your hospital bill covers services provided by the hospital: room, nursing care, meals, housekeeping and linen. It may also include services ordered by your physician: X-rays, laboratory tests, medical supplies and oxygen. The bill does not include charges for your personal physician, surgeon, anesthesiologist, pathologist, emergency physician, radiologist, or other physician assistants. You will receive separate bills from these physicians.(RTL::BVECP) (RTL::FL) (RTL::BITS) (RTL::BITN) (RTL::MULCAT (5 5 (:TYPE-PRESCRIPTION RTL::NONNEG-+-TYPE))) (RTL::MULCAT-NONNEGATIVE-INTEGER-TYPE) (RTL::MULCAT-1 (632 11 (:REWRITE RTL::BITS-SPLIT-AROUND-ZERO)) (285 19 (:REWRITE RTL::BVECP-WITH-N-NOT-A-POSITIVE-INTEGER)) (250 25 (:LINEAR RTL::EXPT-WITH-SMALL-N)) (224 11 (:REWRITE RTL::BITS-TAIL)) (209 11 (:REWRITE RTL::BITS-WITH-INDICES-IN-THE-WRONG-ORDER)) (187 122 (:REWRITE DEFAULT-<-2)) (148 122 (:REWRITE DEFAULT-<-1)) (139 139 (:REWRITE RTL::NON-INTEGERP-<-INTEGERP)) (139 139 (:REWRITE RTL::LESS-THAN-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-RIGHT-HAND-SIDE)) (139 139 (:REWRITE RTL::LESS-THAN-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-LEFT-HAND-SIDE)) (139 139 (:REWRITE RTL::INTEGERP-<-NON-INTEGERP)) (139 139 (:REWRITE RTL::EXPT-COMPARE)) (139 139 (:REWRITE RTL::CANCEL-COMMON-FACTORS-IN-<)) (122 122 (:META CANCEL_PLUS-LESSP-CORRECT)) (115 6 (:LINEAR RTL::BITS-LESS-THAN-X-GEN)) (114 91 (:REWRITE DEFAULT-+-1)) (112 6 (:LINEAR RTL::BITS-LESS-THAN-X)) (110 11 (:REWRITE RTL::BITS-FORCE-WITH-A-CHOSEN-NEG)) (103 91 (:REWRITE DEFAULT-+-2)) (99 33 (:TYPE-PRESCRIPTION RTL::INTEGERP-PROD)) (66 66 (:REWRITE RTL::EXPT-WITH-I-NON-INTEGER)) (66 66 (:REWRITE RTL::EXPT-EXECUTE-REWRITE)) (66 66 (:REWRITE RTL::EXPT-2-EVALUATOR)) (55 11 (:REWRITE A2)) (50 50 (:LINEAR RTL::EXPT-EXCEEDS-2)) (36 18 (:REWRITE RTL::BITS-WITH-I-NOT-AN-INTEGER-2)) (35 13 (:REWRITE DEFAULT--2)) (29 29 (:TYPE-PRESCRIPTION RTL::EXPT-2-POSITIVE-INTEGER-TYPE)) (26 26 (:REWRITE RATIONALP-IMPLIES-ACL2-NUMBERP)) (22 11 (:REWRITE RTL::BITS-WITH-I-NOT-AN-INTEGER)) (19 19 (:REWRITE RTL::BVECP-LONGER)) (18 18 (:REWRITE RTL::BITS-WITH-J-NOT-AN-INTEGER-2)) (18 18 (:REWRITE RTL::BITS-EXPT-CONSTANT)) (13 13 (:REWRITE DEFAULT--1)) (11 11 (:REWRITE RTL::BITS-WITH-X-NOT-RATIONAL)) (11 11 (:REWRITE RTL::BITS-WITH-J-NOT-AN-INTEGER)) (11 11 (:REWRITE RTL::BITS-WITH-BAD-INDEX-2)) (11 11 (:REWRITE RTL::BITS-IGNORE-NEGATIVE-BITS-OF-INTEGER)) (8 8 (:REWRITE RTL::POWER2-INTEGER)) (8 8 (:REWRITE RTL::INTEGERP-MINUS)) (6 6 (:REWRITE RTL::NONNEG-+)) (6 2 (:REWRITE RTL::BVECP-OF-NON-INTEGER)) (3 1 (:REWRITE RTL::INTEGERP-IMPLIES-NOT-COMPLEX-RATIONALP)) (2 2 (:REWRITE RTL::CAT-WITH-N-NOT-A-NATURAL)) (2 2 (:REWRITE RTL::CAT-WITH-M-NOT-A-NATURAL)) (2 2 (:REWRITE RTL::CAT-TIGHTEN-X)) (1 1 (:REWRITE RTL::EXPT-COMPARE-EQUAL)) (1 1 (:REWRITE RTL::EQUAL-OF-PREDS-REWRITE)) (1 1 (:REWRITE RTL::EQUAL-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-RIGHT-HAND-SIDE)) (1 1 (:REWRITE RTL::EQUAL-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-LEFT-HAND-SIDE)) (1 1 (:REWRITE RTL::CANCEL-COMMON-FACTORS-IN-EQUAL)) (1 1 (:REWRITE RTL::BITS-MATCH)) (1 1 (:REWRITE RTL::BITS-EQUAL-IMPOSSIBLE-CONSTANT)) (1 1 (:REWRITE RTL::BITS-DONT-MATCH)) (1 1 (:META CANCEL_TIMES-EQUAL-CORRECT)) (1 1 (:META CANCEL_PLUS-EQUAL-CORRECT))) (RTL::MULCAT-BVECP-SIMPLE (470 4 (:REWRITE RTL::CAT-WITH-M-NOT-A-NATURAL)) (352 5 (:REWRITE RTL::REARRANGE-NEGATIVE-COEFS-<)) (245 4
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Helen had said that the boy-men who had tortured her sister _wanted_ to be what they thought of as beasts. They turned toward the dark and the base, I realized, because they feared the glorious and the high. In truth, they dreaded with a gut-fluttering, heart-crushing terror becoming the bright songs of the earth that they most longed to sing. So it was with me. This new knowledge of myself afflicted me, and I could scarcely bear it, for I had conceived myself almost entirely otherwise. What did I most dread, I wondered? What song did I long to sing? How badly I wished to ask these questions of my grandmother and my mother, to speak and swim once more with my first family whom I had nearly forgotten in my joy of dwelling with Zavijah, Salm, and all my new sisters and brothers who had been slaughtered! Unukalhai, Alkurah, Kitalpha, and Hyadum, too, were gone, lost into the gray-blue deeps of the northern ocean. A single orca remained with whom I might share the wonderings that tormented me. How, though, could I speak of such things with a whale as young as Baby Electra? How could I add to her own torment, which she could scarcely bear? 'It hurts so bad!' she moaned out to me as we swam side by side through the sting of the salty sea. 'There is a hole in me, Arjuna!' She spoke not of the bloody wound that the man's grenade had torn out of her side, but the much deeper loss of whales she had loved. It shocked me that she included me in her remembrance of the murdered, for with an amazing percipience and compassion in one so young, she understood that the violence I had inflicted upon the man had destroyed something precious in me. 'Please do not leave me,' she said as she limped alongside me. 'I never would! I will swim with you until the end of—' 'Please do not leave me in your heart. I cannot live without _you_.' I swam on in silence for a while. Then I tried to divert the stream of her thoughts. 'I should have known that the humans would not want to hear what I had to say,' I told her. 'If I had not opened my big mouth...' 'But what does your mouth have to do with making sounds?' 'It is a figure of speech you never learned.' 'I feel that I learned so much from the humans – and so little.' We moved through the dark gray water, zanging frequently to see what lay ahead of us – and behind. 'All things have a soul,' Baby Electra continued. 'The minnows, the crabs, the starfish, the diatoms – all these beings and so with even the seaweed and the rocks of the green-shrouded shore. But how can it be, Arjuna, that the humans have a soul?' She spoke hyperbolically and too passionately for one so grievously wounded, but she spoke to a point. I said to her: 'What of Gabi, then? What of Helen?' 'They are the exceptions that prove the rule,' she said. 'I sometimes think that Descartes was correct in characterizing animals as soulless automatons, if by animals is meant human beings.' 'You know that humans are not automatons.' 'No, they are something much worse,' she said. 'Any part of reality that vexes them they destroy with a will and a glee. Why have our kind made a covenant with such creatures?' 'I do not know.' 'But you _must_ know! You are an adult, Arjuna.' 'I have not completed my rhapsody. Perhaps I never will.' 'You will! You will! And you will speak to the adults of the things that adults speak of.' 'Once,' I said, 'I overheard my grandmother and mother discussing the Great Covenant.' 'And what did they say?' 'Little that made sense to me. My grandmother said that the Great Covenant is a mystery that may not be questioned.' 'But we orcas question everything!' 'Of course we do. That is what makes my grandmother's pronouncement so mysterious.' 'Perhaps in our questioning, we should question that we question everything.' 'Of course, that is also true. I am glad that you have not allowed your wound to divert you from thought play.' 'I want to live! I want to know... so much!' 'I am glad,' I said to her as we glided beneath the waves above us. 'If we may not question the _why_ of the Great Covenant,' she said, 'may we not wonder about the _where_ and the _how_? From where did it come? How has it been passed down to our kind for so many ages?' 'Only the deep gods,' I said, 'know this. It is said that they persuaded the Old Ones to make covenant with the humans long ago.' 'But orcas do not speak with the deep gods!' 'Once we did,' I told her. 'I wish _I_ could speak with them.' 'And what would you say?' She thought about this as she swam. She winced at the pain that shot through her with every movement of flipper and fluke. 'I would say this,' she told me. 'I have chosen to question the Great Covenant after all. What can be made can be unmade, yes? Perhaps the time has come to bury the Great Covenant in the place we left Bellatrix's and Menkalinan's bodies.' Her voice spread out into the much deeper plaint and moaning of the sea. The waves carried to us the thunder of faraway storms and the much nearer booming of each other's heart. We both listened again and again to the death cries of Zavijah and her sister, and I could not help hearing anew the murdered man's shrieks. The deeps concealed even more disturbing stridencies that we felt touching our bones. All this clamor tinged the water with argrege and inkvol. We swam through these darker colors of sound in remembrance of brighter days. 'I am cold,' Baby Electra said to me as fever set in. She pressed up against me as we swam slowly toward the west. 'Stay close to me, Arjuna.' I pressed my side to her burning flesh. I wished I could soften my skin and remove it so that I might drape it like a cloak over her trembling body. 'I am hungry, too,' she said. So was I. It had been long days and nights of swimming through sunlit and moonshadowed seas since we had eaten. I zanged the restless green waters about us, but only a couple of fish did I detect. 'Where are all the salmon?' she asked. 'The humans have ravished this place. They are like sharks.' I held my breath as I counted my heartbeats, giving up when I reached twenty-three. I aimed zangs of sonar to the west, south, east, and north – and then up and down. What dwelled in the black and whisperless deeps, I wondered, which no orca had ever dared to fathom? 'The humans are _worse_ than sharks,' she added. 'Sharks eat only when they are hungry, but the humans eat just because they like to eat.' 'I have been thinking about sharks myself,' I told her. 'Have you then zanged the two that are following us?' 'Of course I have.' 'Then why did you wait for me to speak of them?' 'I had thought that the pain of your body,' I said, 'would be enough for you to endure.' 'What kind of sharks do you think they are?' Only one kind of shark swam so steadily through such cold water in pursuit of wounded whales. We knew of these sharks as the Magnificent Ones while the humans called them the Great Whites. I told this to Baby Electra, and she seemed to press herself through my side into my clenching belly. 'I have little experience of the Magnificent Ones,' she said. 'If any had thought to come near my family, Pherkad and my mother – Asteropei, too! – would have killed them quickly.' 'If these two come close to you,' I said to her, 'I will kill them, though it might not be quickly.' 'Have you killed such sharks before?' Only in my dreams, I thought. Only in my nightmares. 'No, I have not,' I said. 'But I know how to. My grandmother once instructed me.' 'I do not want you to kill them,' she said. 'What if they wound you as I am wounded? Who would protect me?' 'Let us keep moving,' I said. 'Perhaps they will lose interest in us.' We swam as quickly as Baby Electra could manage toward that red, glowing place where the sun disappears each night
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50260, 18, 13, 30541, 15, 26, 9, 21, 10, 50260, 21, 13, 36717, 15, 21, 9, 1047, 10, 50261, 18, 13, 36679, 15, 26, 9, 23, 10, 535, 50276, 11, 59, 11, 50254, 50254, 50272, 374, 50254, 50275, 19, 50254, 50275, 25, 50254, 50275, 19, 535, 50276, 4218, 32001, 4038, 313, 35811, 16, 78, 63, 20, 13146, 50254, 50272, 18, 15, 19321, 50255, 18, 15, 28871, 50255, 18, 15, 20680, 50255, 18, 15, 20914, 535, 50276, 18310, 19215, 10235, 313, 2188, 6006, 18, 13146, 50254, 50275, 17, 15, 39703, 50255, 17, 15, 24854, 50255, 17, 15, 32631, 50255, 17, 15, 6903, 535, 50276, 11, 39, 5355, 933, 10, 50254, 50254, 50276, 25569, 50254, 42302, 50254, 337, 13, 32332, 50255, 38874, 535, 50276, 36, 18568, 1979, 313, 2188, 10, 50254, 245, 50265, 209, 470, 15, 740, 6806, 470, 15, 938, 6806, 470, 15, 1229, 50268, 17, 15, 1762, 6806, 470, 15, 1762, 6806, 470, 15, 740, 50268, 17, 15, 740, 6806, 470, 15, 938, 6806, 470, 15, 1229, 50268, 17, 15, 740, 6806, 470, 15, 938, 6806, 470, 15, 1229, 535, 50276, 11, 10977, 11, 2491, 323, 941, 4849, 9, 3272, 10, 50254, 50276, 18, 15, 3593, 283, 1099, 15, 1812, 50261, 18, 15, 2511, 283, 1099, 15, 1619, 50261, 18, 15, 1762, 283, 1099, 15, 1619, 50261, 18, 15, 3079, 283, 1099, 15, 1099, 535, 50276, 6060, 13794, 50254, 979, 50263, 470, 18315, 288, 18315, 1903, 61, 50261, 17, 18315, 288, 18315, 818, 61, 50260, 17, 18315, 288, 18315, 1668, 61, 50261, 2106, 1047, 18315, 288, 18315, 2145, 61, 187, 50254, 50254, 50266, 2106, 883, 18315, 465, 18315, 1249, 61, 50263, 2106, 26, 61, 50254, 470, 18315, 465, 18315, 898, 61, 50260, 17, 18315, 465, 18315, 1903, 61, 187, 50254, 50254, 50266, 2106, 1047, 18315, 298, 18315, 1638, 50262, 24832, 465, 18315, 898, 4150, 1099, 18315, 298, 18315, 2030, 50270, 17, 18315, 298, 18315, 7904, 50260, 17, 18315, 298, 18315, 1722, 535, 50276, 7676, 9889, 5728, 50254, 50266, 577, 4699, 50254, 21, 20487, 50254, 1812, 2055, 50254, 1229, 4739, 535, 50276, 688, 6820, 24233, 35138, 51, 5355, 565, 31148, 50256, 1787, 1235, 35138, 51, 5355, 565, 10, 426, 470, 15, 21274, 696, 50275, 1839, 3079, 35138, 51, 5355, 565, 10, 426, 470, 15, 37545, 696, 50275, 1812, 2055, 35138, 51, 5355, 565, 10, 426, 470, 15, 20570, 696, 50275, 1229, 4739, 35138, 51, 5355, 565, 10, 426, 470, 15, 32745, 696, 535, 50276, 9684, 15, 285, 1054, 15, 6322, 50254, 50270, 17, 15, 1525, 883, 285, 470, 15, 4148, 1812, 50267, 17, 15, 4185, 361, 285, 470, 15, 26, 20954, 50267, 17, 15, 2222, 4148, 285, 470, 15, 2055, 3011, 50267, 17, 15, 1525, 361, 285, 470, 15, 26, 26942, 535, 50276, 7676, 14675, 1332, 327, 475, 39, 8769, 19, 63, 50254, 50272, 13525, 14, 6674, 1878, 14, 23600, 4420, 50275, 16135, 14, 6674, 1878, 14, 23600, 4420, 50275, 16135, 14, 6674, 1878, 14, 23600, 4420, 50275, 16135, 14, 6674, 1878, 14, 23600, 4420, 535, 50276, 3233, 16, 1120, 21462, 16, 22041, 50254, 50270, 1787, 1235, 16, 17, 16, 28209, 50260, 1839, 3079, 16, 17, 16, 25121, 50260, 1812, 2055, 16, 17, 16, 22067, 50260, 1229, 4739, 16, 24, 16, 25085, 535, 50276, 8620, 1255, 14, 1171, 14, 8491, 327, 475, 39, 8769, 19, 63, 50254, 50270, 337, 15, 5523, 50255, 18, 15, 4699, 50255, 18, 15, 19634, 50255, 18, 15, 5525, 535, 50276, 21747, 475, 51, 11, 14452, 35138, 42, 11, 8994, 374, 11, 3868, 24222, 42, 5627, 28653, 475, 51, 3853, 18, 9854, 475, 88, 51, 3853, 19, 95, 50275, 11, 51, 3853, 18, 95, 426, 470, 15, 3071, 2055, 61, 50266, 11, 51, 3853, 18, 95, 426, 470, 15, 17, 36208, 61, 50266, 11, 51, 3853, 18, 95, 426, 470, 15, 2922, 1449, 61, 50266, 11, 51, 3853, 18, 95, 426, 470, 15, 17, 29543, 61, 187, 50254, 50254, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 1010, 2904, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 1010, 4529, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 1036, 1036, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 1010, 2251, 535, 50276, 11, 51, 3853, 18, 9854, 475, 88, 51, 3853, 19, 95, 313, 455, 941, 10, 50254, 50270, 11, 51, 3853, 18, 95, 426, 470, 15, 1047, 3583, 61, 50266, 11, 51, 3853, 18, 95, 426, 470, 15, 1166, 2526, 61, 50266, 11, 51, 3853, 18, 95, 426, 470, 15, 1012, 3046, 61, 50266, 11, 51, 3853, 18, 95, 426, 470, 15, 9138, 61, 187, 50254, 50254, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 1093, 1671, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 1093, 4148, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 746, 1423, 50266, 11, 88, 51, 3853, 19, 95, 426, 470, 15, 1166, 4185, 535, 50276, 45, 1662, 383, 2171, 15, 5241, 285, 7793, 313, 70, 6256, 18221, 6006, 20, 13146, 50257, 17, 15, 16717, 285, 4150, 17, 15, 17809, 50266, 17, 15, 30592, 285, 4150, 17, 15, 22313, 50266, 17, 15, 25472, 285, 4150, 17, 15, 26422, 50266, 17, 15, 21345, 285, 4150, 17, 15, 48442, 187, 50276, 7078, 38944, 187, 187, 10322, 14, 746, 14, 520, 19044, 14, 85, 4699, 64, 3235, 374, 187, 187, 5146, 2490, 187, 19030, 5533, 16095, 313, 18221, 582, 5533, 14636, 16, 85, 641, 279, 14636, 313, 3272, 10, 323, 1401, 42, 8200, 1401, 2267, 8200, 1401, 8296, 8200, 285, 1401, 3252, 12530, 535, 50276, 5065, 15, 50273, 35, 857, 16095, 313, 18221, 10, 50275, 57, 14, 1402, 50266, 35, 857, 14636, 16, 53, 641, 279, 14636, 313, 3272, 10, 50275, 57, 14, 1402, 187, 50276, 9794, 23461, 4372, 9625, 16213, 187, 50276, 424, 42, 424, 50273, 36, 883, 14, 48, 20, 50265, 18, 15, 30072, 9, 21, 10, 50269, 36, 26, 14, 36, 740, 14, 36, 883, 50255, 11238, 15, 19, 9, 20, 10, 187, 50276, 47, 18, 14, 47, 19, 50273, 18, 15, 24562, 9, 20, 10, 50267, 47, 19, 14, 47, 18, 14, 36, 883, 14, 48, 20, 50273, 21151, 15, 22, 9, 20, 10, 50254, 2490, 50276, 36, 22, 14, 36, 26, 50273, 18, 15, 32006, 9, 21, 10, 50267, 47, 18, 14, 47, 19, 14, 36, 26, 14, 36, 22, 50272, 2106, 20333, 15, 25, 9, 20, 10, 50254, 187, 50276, 48, 20, 14, 36, 1093, 50274, 18, 15, 16587, 9, 21, 10, 50267, 36, 18, 14, 48, 18, 14, 36, 25, 14, 36, 24, 50272, 22, 15, 17, 9, 22, 10, 50254, 50275, 187, 50254, 50272, 330, 19, 14, 48, 19, 14, 36, 20, 14, 36, 21, 50272, 2106, 19, 15, 24, 9, 22, 10, 50254, 50276, 187, 50276, 424, 2267, 424, 50274, 36, 23, 14, 48, 19, 50264, 18, 15, 22391, 9, 25, 10, 50269, 36, 23, 14, 36, 24, 14, 36, 25, 50254, 12708, 15, 20, 9, 22, 10, 187, 50276, 47, 18, 14, 36, 21, 50273, 18, 15, 39069, 9, 24, 10, 50267, 47, 20, 14, 47, 19, 14, 36, 23, 14, 48, 19, 50272, 2106, 17864, 15, 24, 9, 23, 10, 50254, 187, 50276, 36, 24, 14, 2019, 50273, 18, 15, 48549, 9, 23, 10, 50267, 47, 19, 14, 47, 20, 14, 36, 25, 14, 36, 26, 50272, 2106, 17184, 15, 18, 9, 23, 10, 50254, 187, 50276, 47, 19, 14, 47, 20, 50273, 18, 15, 24424, 9, 23, 10, 50267, 36, 1010, 14, 48, 20, 14, 36, 805, 14, 36, 883, 50275, 18, 15, 18, 9, 883, 10, 50254, 50276, 187, 50276, 36, 25, 14, 36, 26, 50273, 18, 15, 28757, 9, 25, 10, 50267, 36, 21, 14, 47, 18, 14, 36, 20, 14, 52, 19, 50272, 2106, 18, 15, 17, 9, 740, 10, 50254, 2490, 50276, 48, 19, 14, 36, 22, 50273, 18, 15, 32631, 9, 24, 10, 50254, 50254, 50266, 2490, 50276, 424, 8296, 424, 50275, 36, 1010, 14, 48, 18, 50265, 18, 15, 27018, 9, 22, 10, 50269, 36, 1012, 14, 36, 1047, 14, 36, 1010, 50256, 11238, 15, 26, 9, 21, 10, 187, 50276, 47, 20, 14, 36, 1166, 50274, 18, 15, 30965, 9, 23, 10, 50267, 47, 18, 14, 47, 19, 14, 36, 1010, 14, 48, 18, 50273, 20070, 15, 18, 9, 21, 10, 50254, 2490, 50276, 36, 883, 14, 2019, 50274, 18, 15, 44828, 9, 24, 10, 50267, 47, 19, 14, 47, 18, 14, 36, 1012, 14, 36, 24, 50273, 15907, 15, 25, 9, 21, 10, 50254, 2490, 50276, 47, 18, 14, 47, 19, 50273, 18, 15, 22359, 9, 22, 10, 50267, 36, 1166, 14, 47, 20, 14, 36, 1093, 14, 52, 18, 50274, 26, 15, 21, 9, 24, 10, 50254, 50275, 187, 50276, 36, 24, 14, 36, 1012, 50274, 18, 15, 45475, 9, 24, 10, 50254, 50254, 50266, 2490, 50276, 48, 18, 14, 36, 1036, 50274, 18, 15, 36356, 9, 22, 10, 50254, 50254, 50266, 2490, 50276, 424, 3252, 424, 50274, 36, 740, 14, 48, 18, 50265, 18, 15, 29827, 9, 23, 10, 50269, 36, 740, 14, 36, 883, 14, 36, 805, 50256, 11238, 15, 21, 9, 22, 10, 187, 50276, 36, 1036, 14, 39, 50273, 18, 15, 24137, 9, 24, 10, 50267, 47, 19, 14, 47, 18, 14, 36, 740, 14, 48, 18, 50273, 15907, 15, 21, 9, 23, 10, 50254, 2490, 50276, 47, 18, 14, 47, 19, 50273, 18, 15, 25085, 9, 22, 10, 50267, 47, 18, 14, 47, 19, 14, 36, 805, 14, 36, 1012, 50274, 2106, 17184, 15, 20, 9, 23, 10, 50254, 187, 50276, 36, 805, 14, 36, 1012, 50275, 18, 15, 37972, 9, 24, 10, 50267, 48, 18, 14, 36, 746, 14, 48, 19, 14, 36, 938, 50274, 2106, 21151, 15, 25, 9, 21, 10, 50254, 187, 50276, 48, 18, 14, 36, 746, 50274, 18, 15, 20611, 9, 23, 10, 50267, 48, 19, 14, 36, 746, 14, 36, 1508, 14, 48, 740, 50275, 2106, 18804, 15, 19, 9, 21, 10, 50254, 187, 50254, 50272, 330, 1797, 14, 36, 938, 14, 36, 1731, 14, 48, 21, 50275, 2106, 3832, 15, 17, 9, 23, 10, 50254, 2490, 50254 ]	FN~2~O~10~ Formula weight 400.42 459.95 429.93 626.62 Temperature 293(2) 293(2) 293(2) 293(2) Wavelength (Å) 0.71073 0.71073 0.71073 0.71073 Crystal system Triclinic Triclinic Orthorhombic Monoclinic Space group P-1 P-1 Pbca P2~1~ a (Å) 9.3040(19) 6.0180(12) 13.698(3) 11.838(2) b (Å) 10.507(2) 8.2370(16) 7.6260(15) 9.4500(19) c (Å) 12.075(2) 21.600(4) 38.908(8) 14.514(3) α (°) 68.70(3) 87.08(3) 90.00 90.00 β (°) 81.40(3) 87.46(3) 90.00 100.41(3) γ (°) 67.99(3) 82.30(3) 90.00 90.00 Volume (Å^3^) 1,019.5(4) 1,058.9(4) 4,064.4(14) 1,596.9(6) Z 2 2 8 2 Calculated density (Mg/m^3^) 1.304 1.443 1.405 1.303 Absorption coefficient (mm^−1^) 0.090 0.406 0.414 0.101 F(000) 420 476 1,776 660 Crystal size (mm) 0.10 × 0.20 × 0.30 0.05 × 0.05 × 0.10 0.10 × 0.20 × 0.30 0.10 × 0.20 × 0.30 θ range for data collection(°) 1.81--25.36 1.89--25.28 1.05--25.28 1.43--25.25 Index ranges 0 ≤ h ≤ 11\ 0 ≤ h ≤ 7\ 0 ≤ h ≤ 16\ −14 ≤ h ≤ 13\ −11 ≤ k ≤ 12\ −9\ 0 ≤ k ≤ 9\ 0 ≤ k ≤ 11\ −14 ≤ l ≤ 14 ≤ k ≤ 9 −25 ≤ l ≤ 25 0 ≤ l ≤ 46 0 ≤ l ≤ 17 Reflections collected 4002 4239 3688 3091 Independent reflections \[R(int)\] 3750 \[R(int) = 0.045\] 3843 \[R(int) = 0.061\] 3688 \[R(int) = 0.034\] 3091 \[R(int) = 0.052\] Max. and min. transmission 0.9911 and 0.9736 0.9800 and 0.9605 0.9597 and 0.8857 0.9900 and 0.9704 Refinement method on F^2^ Full-matrix least-squares Full-matrix least-squares Full-matrix least-squares Full-matrix least-squares Data/restraints/parameters 3750/0/271 3843/0/272 3688/0/253 3091/7/388 Goodness-of-fit on F^2^ 1.005 1.002 1.032 1.004 Final R indices \[I \> 2σ(I)\]; R~1~, wR~2~ R~1~ = 0.0688\ R~1~ = 0.0854\ R~1~ = 0.0740\ R~1~ = 0.0656\ wR~2~ = 0.1508 wR~2~ = 0.1592 wR~2~ = 0.1616 wR~2~ = 0.1567 R~1~, wR~2~ (all data) R~1~ = 0.1452\ R~1~ = 0.1766\ R~1~ = 0.1359\ R~1~ = 0.1000\ wR~2~ = 0.1835 wR~2~ = 0.1897 wR~2~ = 0.1922 wR~2~ = 0.1798 Largest diff. peak and hole (e·Å^−3^) 0.149 and −0.169 0.451 and −0.266 0.325 and −0.358 0.226 and −0.577 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------- molecules-19-01302-t002_Table 2 ###### Selected bond lengths (Å), bond angles/torsion angles (°) for I, II, III, and IV. Comp. Bond lengths (Å) X-ray Bond angles/Torsion angles (°) X-ray --------- ------------------ ---------------- -------------------------------- ---------- I C11-O3 1.391(4) C9-C10-C11 104.2(3) N1-N2 1.374(3) N2-N1-C11-O3 173.5(3) C5-C9 1.472(4) N1-N2-C9-C5 −172.8(3) O3-C18 1.360(4) C1-O1-C8-C7 5.0(5) C2-O2-C3-C4 −2.7(5) II C6-O2 1.326(8) C6-C7-C8 106.3(5) N1-C4 1.417(7) N3-N2-C6-O2 −179.7(6) C7-Cl 1.732(6) N2-N3-C8-C9 −176.1(6) N2-N3 1.357(6) C15-O3-C12-C11 1.1(11) C8-C9 1.479(8) C4-N1-C3-S2 −1.0(10) O2-C5 1.414(7) III C15-O1 1.351(5) C13-C14-C15 104.9(4) N3-C17 1.412(6) N1-N2-C15-O1 178.1(4) C11-Cl 1.730(7) N2-N1-C13-C7 177.8(4) N1-N2 1.365(5) C17-N3-C18-S1 9.4(7) C7-C13 1.477(7) O1-C16 1.424(5) IV C10-O1 1.392(6) C10-C11-C12 104.4(5) C16-F 1.380(7) N2-N1-C10-O1 177.4(6) N1-N2 1.388(5) N1-N2-C12-C13 −176.3(6) C12-C13 1.499(7) O1-C19-O2-C20 −173.8(4) O1-C19 1.404(6) O2-C19-C23-O10 −174.2(4) C21-C20-C26-O4 −61.0(6)
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We aren’t talking just about Internet of Things (IoT), now we are talking about Internet of Everything (IoE). IOTA creates an environment for IoE Now, IOTA is coming! IOTA Foundation create an environment for Internet of Everything (IoE). The IOTA platform can be presented as a bridge via systems can connect, communicate and evolve. The interconnectivity is the key for our new economy. With interconnectivity comes incredible huge amount of data that devices send and receive every seconds. To take full benefit from the IoT and IoE we have to find a way how to connect the billions of cyber-physical systems together. The network we set up has to gain our trust. Human kind is nowadays dependant on Internet. Can you imagine what will happen if the Internet goes down. Even just for one day or one hour. The future of fully operational status of our society and economy lies in the 24 hour-stable communication (interconnection). The Internet is by far the most efficient medium but we can’t afford to use just that. The consequences of depending on one single channel would be catastrophic. IOTA developed a protocol on which the machines can communicate via other channels, such as Bluetooth, Z-wave, ZigBee or LoRa. The future of connectivity might lie beyond the Internet itself. IoE: Sensors as an example The market of IoE rapidly increasing. Let's talk about sensors, the area of market that you might not heard about yet, but will have significant impact on our economy and social life. The number of sensors especially due to demand in SmartHomes and SmartCities is growing like crazy. Sending and receiving data is just the beginning of the chain. There is no doubt we will need more computational power. The big data in our new economy needs to be analyzed first and reported as soon as possible. Cloud storage nowadays cannot provide us real-time results that we require. We need smart sensors, that have computational ability itself and are able to work with other stations as well. Instead of Cloud computing we talk about Fog computing and Mist computing. Find the difference in an easy explanation. There will be billions of sensors by the 2025. Data won't be shared freely and that is a potential for cooperation among companies and individuals. IOTA will provide the platform for exchange (data for money). Just imagine that once you gather some data, you can sell them, as well as you can sell your free storage. Selling it means to get compensation with IOTA currency. There won't be just distributed computing, data and storage, but also distributed brandwith and energy. The future of Internet of Everything is coming. But untill it reaches our everyday life, we need to do some changes starting on recognition of smart devices. Identity of Things (IDoT) To make IoT ecosystem secure, we need to think about machines and devices differently, not just as a metal things without life. We need to consider each device as its own identity. Why? Because the identity carries some attributes and we cannot securely and efficiently work with IoT without knowing more. One of the biggest challenge for IoT will be the maintenance. Creation is hard process, but to maintain IoT (means also keep them resilient) is a long-term task, that cannot be undervalued. Look at any software and application that you use on PC or smartphone. How many times did you update it? Maintenance is a new angle of re-creation process. So far we use one unique identifier for devices, but that is not enough to satisfy our future needs — secure status and smooth long term usage. Identity of Things (IDoT) will become a new standard. The question is when it will happen. To give you an idea, we need to create IoT with some specific attributes, such as: who manufactured it when it was deployed what is the expected life time cycle who owns it what data is it gathering For deeper understanding I recommend you to read IOTA development roadmap. The biggest chalenge for society 2.0 With growing number of smart devices, there will be more data traffic. Data means informations and informations are money (or power, if you prefer). All the IoT (IoE) communication must be encrypted. One of the IOTA modul is called Masked Authenticated Messaging and its job is to secure and encrypt entire data stream. Only authorized parties will be able to read and reconstruct the stream. Encrypting the data streaming is the whole area that needs to be developed with a new way of approach. Far by most important is security. As our society technologically grow, we became dependant on software and hardware. We become more vulnerable to software or hardware malfunction or hacker's attacks. The future will take place even more in cyberspace, so security should be our first priority when we aiming for a tech change. Quantum computation and mechanics cause headaches to security engineers, because in the coming decades we can see very real possibility of scalable quantum computers. This will disrupt most of cryptographic protocols used today. So in another words, our world can become insecure with quantum computers. If you want to go more in depth, have a look on article How secure will our data be in the post-quantum era? No-one can be ready for this cybersecurity challenge, but IOTA is very proactive in solving solution. It deploys 2 separate mechanisms to safe-guard against quantum threats. You can read about security issues in the Tagle whitepaper. All in one solution is replaced by layers and eXtension Interface The approach for developing IOTA is not to build all in one universal solution, but instead design and engineering core simple principles (they call it often underlaying edger protocol) and then extend its utility through the IOTA eXtension Interface (IXI). The advantage is that anyone can build IXI for their own needs, it is fast and very flexible solution to speed up development. IXI modules are the reason why IOTA will stay lightweight and optimized. History of IOTA We heard about IOTA first in 2014 when a small team developed a brand new type of microprocessor for IoT and distributed computing. The persistent problem in deeper development was lack of a clear incentive for interoperability. It was crucial. Machine 2 machine economy is and will be based on micro-transaction. It is getting better but even today we still face prohibitive fees, inflexibility and perpetual problems with scalability in blockchain development. IOTA was born as an idea to create a compensation layer that will act as the building blocks of the Economy of Things where machines can trade resources effectively and securely on-demand. IOTA main network went live on 11th July. The protocol and data transfer on the distributed and decentralized Tangle has been launched. The first stage: IOTA core live, establishing the IOTA Foundation, moving the community’s chat over to Slack, completing some partnerships, IOTA on exchange market, spreading into the world The second stage: extending IOTA’s utillity, open IOTA to anyone that want to build on top of the IOTA network The third stage: development of hardware (project's name is Jinn project), a brand new type of microprocessor for IoT, a hardware implementation hasher for IOTA’s ‘Curl hash function’ Core founding IOTA Team Sonstebo Sergey Ivancheglo Serguei Popov Dominik Schiener Find more about IOTA team. Ecosystem To start an open source project is not hard, but to grow it is incredibly difficult. The successful open source project need a great ecosystem surrounding it. The reason for it is simple. Ecosystem will deliver long term sustainability. IOTA in 2017 IOTA already proceed till the end of 2016 over 3 million successful transactions. Just to remind you, IOTA is the world’s first digital settlement system without any fees. Even though IOTA has been already launched, the year 2017 will be the first year when big changes start occurring. There are lots of projects that are in developing mode (since 2015) and will be reviled and launch soon. The number one IOTA priority of 2017 is to make the IOTA platform developer inviting and friendly. Thanks to active core team and collaboration with the community the IOTA Lightwallet went live, Mobile wallet for Android has been released and dedicated hub for tutorials around IOTA is growing (client libraries in Javascript, Python, C#, Java and Go). What is IOTA Sandbox and why is it so important? The IOTA Sandbox is here for developers and provides them tools, utilities and environment for “just code”. They don't need to download anything, setting up their PC or app, they are not disturb, they can just code. The Sandbox is important because IOTA is open source, so anyone can participate on development. IOTA needs more developers who build core and apps to grow the ecosystem and make it world-wide. Do you want to participate? Learn IOTA. IOTA Foundation is responsible for developing and maintaining the core open source protocol IOTA. It is registered in Germany as an official non-profit Stiftung. Real examples of IOTA use There are many M2M examples but if you are looking for one that is tightly connected to your life right now, check this one. The internet connection is provided (sold to you) by tele

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has committed against people of color and women here and abroad. You will understand the relationships between power, privilege, and systems of oppression. Sometimes, this will overwhelm you, but I hope it never drowns out your faith in humanity. I hope you understand the worst of humanity but believe in its best. Don’t worry these are just a few of my hopes and dreams for you. I haven’t figured all of the things on this list out, but that’s why you’re here. My only real hope is that you are better than me, that this life and this world seem kinder somehow. The Black Student Alliance Invitational (BSAI) is a four-day event on campus for prospective students that identify as Black. The weekend is filled with exciting events that enable the prospective students to experience many facets of the college experience. I was lucky enough to attend this event last March. Now that I work at the Mary Lou Williams Center for Black Culture, the center that sponsors the event, as well as am a co-chair of one of the planning committees, I cherish my memories of BSAI even more. My first day at BSAI, I arrived at Duke and got to meet my host, whom I instantly had a connection with. I also met a girl who is now my best friend at Duke. The rest of the day evolved into a night of bowling, and the rest of the weekend turned into a time I’ll never forget. My BSAI experience came just days after an African American student had been harassed by a racist chant performed by a fraternity on campus. The community’s willingness to discuss the incident, and not shy away from it, was inspiring. The discussion of racial issues was something new to me, which I appreciated and was comforted by. I am from a predominately white community where others recognizing my Blackness was almost unheard of. The best I got was a "Black History Month" prayer by our school’s resident nun. It wasn’t until I came to BSAI that I realized that there are people that actually look like me, think like me, and live the struggle like me. Finding that comfort solidified my decision to attend Duke. I truly believe that without the opportunity to attend BSAI many students would not have the ability to experience what it is like to be on Duke's campus, and possibly not end up choosing to enroll at Duke. Allowing students to spend the weekend here greatly influences their decision to enroll at Duke. Being a top ten university, the majority of students that apply, and are accepted to Duke, also apply, and are accepted, to other top schools. The biggest deciding factor, in my opinion, in attending any institution, is the experience that one has on campus. I believe that the experience that one has at BSAI separates Duke from the rest. I can never be anything less than grateful for the experience that BSAI provided me. It allowed me to establish a foundation on this campus. This foundation has flourished into a job as an Abele Ambassador at the Marylou Williams Center, and an active member of the black community on campus. Alexandria Miller, History and African American Studies Major, class of 2017 As part of the Students of the Caribbean Association, we have been gearing up for our best Caribbean Awareness Week yet. This year, we’ll bring back returning treats like a traditional steel pan band and a Monday Motivations collaboration with the Center for Multicultural Affairs. This year will also bring about new traditions including a keynote speaker and will culminate with our annual Caribana festival. It goes without saying that Caribbean Awareness Week is, at least in my opinion, the most wonderful time of the year! Being able to celebrate my Caribbean heritage has been one of the most significant attributes of my college experience. From our annual J’ouvert celebration till four in the morning, debating Caribbean politics, or discussing how society misinterprets new songs in our Caribbean dialects, there has been no greater family to me here than my fellow Caribbean and Caribbean-American friends here. If you are from the Caribbean or just want to get to know more about Caribbean culture, I encourage you to join SOCA this year for Caribbean Awareness Week 2016 from Thursday, March 24th through Friday, April 1st this year and follow us on social media @DukeSOCA to stay up-to-date! There will be tons of food, great music, and even greater people! We hope to see you there! In recent years, more and more Black women are wearing their natural hair unapologetically; and it’s beyond beautiful. After decades of straightening, chemically altering and manipulating our curls to fit a beauty standard that wasn’t ours, we have started to love and appreciate our curls, kinks and coils. Due to the positivity of this movement, many black women have also embraced their looks and learned to love themselves and recognize their beauty. There is more representation of Black women in media, and there are more cosmetic companies that cater to Black women. Due to the magnitude of this movement, Black women’s hair and appearance has become a highly politicized aspect of our lives. One of these conversations is based on the professionalism (or lack thereof) of Black women’s hair. A little over a month ago, Lara Oddoffin had her job revoked because her braids were not “professional” enough. The company emailed her stating, “If you are unable to take them out I unfortunately won't be able to offer you any work.” Many other women have been criticized for sporting their natural curls and afros. How is the hair that grows out of my scalp not deemed acceptable? Why do I have to succumb to a white standard of beauty and professionalism to be accepted? Or even land a job? Why does my decision to wear my hair exactly the way it grows deemed “bold” or even considered a movement? Why does my hair somehow define me? Despite the over politicized discussion of Black women’s hair, many people still embrace the natural hair movement. But, while there has been a lot of positive impact of the natural hair movement, we often fail to recognize the few failures of the movement. Whether it is in media or on social network, whenever we’re appreciating and promoting the beauty of Black women, we tend to focus on women who are close in line with the white beauty standard. Women who have fairer skin, softer curls and thin figures are the ones most people think of when it comes to beauty in the Black community. We use Black celebrities to claim our celebration of Black beauty, when in reality, we somehow internalize and Idealize values for Eurocentric beauty standards even within our own community. Zola Ndlovy of wordpress.com perfectly puts it as, “In the economy that is black beauty, being light skinned is a social currency.” Or in this context, reflecting beauty standards that resemble white beauty standards is the social currency. This is not even what is most problematic. The big issue is how we fail to see the diversity of our beauty. The fact that we differentiate between what constitutes an “acceptable” type of Black woman and what doesn’t, is a huge problem. The fact that we rarely see Black women who don’t have light skin, a thin figure, and “nice hair” just shows how narrow our society’s thinking is when it comes to the beauty of Black women. Phrases like “…cute for a black girl,” or “…too black” emphasize the negative stigma that already exists in the politicized world of Black beauty, yet they’re things we continue to hear day to day. The challenge is to recognize the diverseness of Black women, while redefining what beauty means, and shifting it away from internalized hatred for our own physical features; it is knowing that if we say “black is beautiful”, we truly do mean all of our blackness is beautiful, not just the parts that look “acceptable”. After all, beauty is not hair, or skin or figure. Beauty is knowing one’s identity and self worth. Whether it is your natural curls, your kinky fro, or your relaxed hair, what constitutes your beauty is so much more than just the surface. For any Black adult who has ever been to college, more than likely some of the pivotal snapshots of our college careers are linked to the events and programs that were held by members of the National Pan-Hellenic Council (NPHC). Whether it be one of their academic enrichment programs, neophyte presentations or infamous step shows and parties, we sometimes frame our college years around these unique African-American organizations. Too often though, we take these organizations and their many contributions for granted, seeing them as a prop to our collegiate experiences. But, what if we took the mundane seriously? What if black constructions of brotherhood and sisterhood were actually works of art? And, what if the traditions emanating from Black Greek letter organizations were also works of art too? As such, this two-part exhibit begs all of its onlookers to consider the NPHC experience in a way that elevates it to art. “Divine” asks us to consider NPHC interactions as art. “Movement” on the other hand, asks us to consider stepping as both iconography and artistic. Join me in a consideration of “Divine Movement.” Black History Month 2016 has been one to remember. From Black Hollywood standing together through the #OscarsSoWhite hashtag to voice their discontentment with the lack of Black nominees for the second straight year, to Beyonce’s electric pro-Black performance at the Super Bowl, to Kendrick Lamar’s breathtaking performance at

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in Pretoria, the local government and housing department in Gauteng said on Thursday. The houses were handed over on the spot on Tuesday to the legitimate beneficiaries after the department successfully evicted the illegal occupants, said spokesperson Motsamai Motlhaolwa. “At least 50 houses and 273 stands were illegally occupied, thus creating a delay in the continuation of the project in the area to build houses for beneficiaries,” said Motlhaolwa. A partnership between the department, the City of Tshwane and the community established that some houses and stands were sold to illegal occupants and foreign nationals by people claiming to be community leaders. MEC Ntombi Mekgwe welcomed the positive and quick response by the department in dealing with the crisis. She said the issue had become a major problem for the department and committed that her department will continue to work hard to deal with such lawlessness. “We cannot allow this to become a norm. We will continue to use all available avenues to ensure that illegal occupation does not happen under our watch,” said Mekgwe. She said the move should be a warning to would-be illegal occupants. “Beneficiaries have been waiting patiently for their houses and I urge others to follow the correct procedures and await their turn.” The department had began with its preparations to evict the illegal occupants of the 273 stands to allow the contractor to continue with the construction of more houses. - Sapa// Copyright 2016 The Chromium Authors. All rights reserved. // Use of this source code is governed by a BSD-style license that can be // found in the LICENSE file. #ifndef SKIA_EXT_TEXTURE_HANDLE_H_ #define SKIA_EXT_TEXTURE_HANDLE_H_ #include "third_party/skia/include/gpu/gl/GrGLTypes.h" namespace skia { // TODO(bsalomon): Remove both of these conversions when Skia bug 5019 is fixed. inline GrBackendObject GrGLTextureInfoToGrBackendObject( const GrGLTextureInfo& info) { return reinterpret_cast<GrBackendObject>(&info); } inline const GrGLTextureInfo* GrBackendObjectToGrGLTextureInfo( GrBackendObject object) { return reinterpret_cast<const GrGLTextureInfo*>(object); } } // namespace skia #endif // SKIA_EXT_TEXTURE_HANDLE_H_ ; Copyright (C) 2013 Apple Inc. All rights reserved. ; ; Redistribution and use in source and binary forms, with or without ; modification, are permitted provided that the following conditions ; are met: ; 1. Redistributions of source code must retain the above copyright ; notice, this list of conditions and the following disclaimer. ; 2. Redistributions in binary form must reproduce the above copyright ; notice, this list of conditions and the following disclaimer in the ; documentation and/or other materials provided with the distribution. ; ; THIS SOFTWARE IS PROVIDED BY APPLE INC. AND ITS CONTRIBUTORS ``AS IS'' ; AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, ; THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR ; PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL APPLE INC. OR ITS CONTRIBUTORS ; BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR ; CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF ; SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS ; INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN ; CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ; ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF ; THE POSSIBILITY OF SUCH DAMAGE. (webkit-powerbox) (shared-preferences-read-write "com.apple.quicktime.plugin.preferences") (allow file-read* file-write* (home-library-subpath "/Caches/QuickTime") (home-library-preferences-literal "/QuickTime Preferences")) (allow network-bind (local ip)) Does anyone currently assign TI-Nspires or other calculators to their students like a textbook at the beginning of the year? If yes, do they have a document or district policy on it that you can share? Any tips, pros or cons?Revista Indicadores 2018 RevistaIndicadores2018-final02 - Page 52 GESTION EMPRESARIAL BUSINESS MANAGEMENT Una de las prioridades de todos los hoteles que integran Mayakoba es el bienestar de los colaboradores, realzando valores de educación, respeto, solidadridad, el valor de la familia, un estilo de vida saludable, entre otros. Te invitamos a conocer las buenas prácticas empresariales que realiza cada uno de los hoteles. One of the priorities of all the hotels that make up Mayakoba is the wellbeing of employees, enhancing values of education, respect, solidarity, the value of the family, a healthy lifestyle, among others. We invite you to learn more about the good business practices carried out by each of the hotels. Para Andaz es fundamental la capacitación y el crecimiento de nuestros colaboradores, así como su bienestar, para ello cuenta con diversos programas corporativos. VIDEO ANDAZ MAYAKOBA 52 | Mayakoba Sustentable 2018 For Andaz, the training and growth of our employees, as well as their well- being, is fundamental, for which it has various corporate programs.Pharmacological and immunological characterization of the Leu5 analogue of human beta-endorphin. The potencies of beta h-endorphin, Met (O)5-beta h-endorphin, and synthetic Leu5-beta h-endorphin have been compared in three bioassays of opioid activity, and in two radioimmunoassays. In all assays, a peptide isolated from hemodialysates from a psychotic patient behaved like Leu5-beta h-endorphin; it has been distinguished unambiguously from beta h-endorphin and Met(O)5-beta h-endorphin. Leu5-beta h-endorphin was one-fifth as potent as beta h-endorphin in guinea pig ileum myenteric plexus, but was only slightly less active in mouse vas deferens and in guinea pig brain opiate receptor binding assay. The low cross-reactivity of Leu5-beta h-endorphin relative to beta h-endorphin with an antiserum raised to beta-endorphin suggests that the preferred solution conformations of these peptides are different. In all bioassays beta h-endorphin was 2- to 3-fold less potent than beta c-endorphin.This invention relates generally to microprocessing, and more particularly to providing methods to improve floating point arithmetic operations. In most processors, it is common to see some type of floating point unit (FPU) or other processing unit that completely implements (or at least has enhanced support for) various floating point square root instructions. Implementations of these instructions are based on popular square root algorithms, including non-restoring SRT (Sweeney Robertson Tocher) algorithms, Newton-Raphson algorithms, Goldschmidt algorithms and others. Errors may occur during execution of these instructions using any of various algorithms, either due to errors in the design (including the algorithm itself) or due to circuit malfunctions such as manufacturing faults or rare environmental disturbances. Functional checking of these types of floating point square root algorithms and their results using formal verification techniques is not currently available, and such checking would only serve to eliminate design flaws, as opposed to malfunctions occurring during execution. Accordingly, other techniques have been devised to try and verify the correctness of the algorithm and/or the result. For example, previous machines have focused on verifying the internal verifiable mathematical operations of the square root using parity and residue checks. While these techniques can verify the correctness of each internal operation, they do not speak to the correctness of the square root algorithm or the final result. Thus, it would be desirable to be able to detect errors in the final result of a floating point square root algorithm, particularly to detect errors occurring due to a circuit malfunction. Such an ability would be useful in providing a method to verify the actual results of a square root operation without the need to verify each mathematical step in the algorithm.Q: Move a sequential set of commits from one (local) branch to another Is there a way to move a sequential set of commits from one (local) branch to another? I have searched quite a bit and still haven't found a clear answer for what I want to do. For example, say I have this: master A---B---C \ feature-1 M---N---O---P---R---Q And I have decided that the last 3 commits would be better off like this: master A---B---C \ feature-1 M---N---O

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$(E_i)$ in $Z$. Then for every $\eta>0$ with $(1+C)\eta<1$ and for every sequence $(z_i)\subset S_X$ with $d(z_i,Z_i)<\eta$ for all $i\in{\mathbb{N}}$, there is a subsequence $(x_i)$ of $(z_i)$ and a weakly null sequence $(y_i)\subset S_X$ such that $||x_i-y_i||<2(1+C)\eta$ for all $i\in{\mathbb{N}}$. Indeed, we can pass to a weakly Cauchy subsequence $(x_i)$ of $(z_i)$ such that $$\label{P1E1} ||P^E_{[1,n]}(x_i-x_j)||< \eta 2^{-j}\quad\forall n\in{\mathbb{N}}\textrm{ and }i>j\geq n.$$ Since $d(x_i,Z_i)<\eta$, we have $||P^E_{[1,i]}x_i||<C\eta$ for all $i\in{\mathbb{N}}$. Since $(E_i)$ is shrinking, the sequence $(P^E_{(i,\infty)}x_i)$ is weakly null, and so for each $n\in{\mathbb{N}}$ there exists $(a_i^{(n)})_{i=n}^{K(n)}=(a_i)_{i=n}^K\subset [0,1]$ such that $\sum_{i=n}^K a_i=1$ and $||\sum_{i=n}^K a_i P^E_{(i,\infty)}x_i||<\eta$. Set $$y_n=\frac{x_n-\sum a_i x_i}{||x_n-\sum a_i x_i||}.$$ We have that $$\begin{aligned} \left\Vert\sum_{i=n}^K a_i x_i\right\Vert\leq\sum_{i=n}^K a_i||P^E_{[1,i]}x_i||+\left\Vert\sum_{i=n}^K a_i P^E_{(i,\infty)}x_i\right\Vert <\sum_{i=n}^K a_i C\eta+\eta =(1+C)\eta\ ,\end{aligned}$$ which implies that $||x_n-y_n||<2(1+C)\eta$. We also have $$\begin{aligned} ||P_{[1,n]}y_n||\leq 2\Big\|P_{[1,n]}(x_n-\sum a_i x_i)\Big\| \leq2\sum a_i||P_{[1,n]}(x_n-x_i)||<2\eta 2^{-n}\ ,\end{aligned}$$ which tends to zero as $n\rightarrow\infty$. Hence $(y_n)\subset S_X$ is weakly null as $(E_i)$ is shrinking. We now continue with the proof of the implication $(c)\Rightarrow(b)$. Assume that $S$ does not have a winning strategy for the $(A,{\varepsilon})$ game for some ${\varepsilon}>0$. As this game is determined [@Ma] , there exists a winning strategy $\phi$ for the point chooser. The function $\phi$ takes values in $S_X$: if $(k_i),(m_i)\in[{\mathbb{N}}]^\omega$ are the choices by player $S$ and if $z_n=\phi(k_1,m_1,...,k_n,m_n)$ for all $n\in{\mathbb{N}}$, then $d(z_i,Z_{m_i})<{\varepsilon}2^{-i}$ for all $i\in{\mathbb{N}}$ and $(k_i,z_i)\not\in \overline{A_{5C{\varepsilon}}}$. We can, of course, assume that $(1+C){\varepsilon}<1$. For each $\alpha\in T_\infty^{\textrm{even}}$ set $z_\alpha=\phi(\alpha)$. Then $(z_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ is a normalized even tree in $X$ no branch of which is in $\overline{A_{5C{\varepsilon}}}$. Its nodes $(z_i)=(z_{(k_1,\dots,k_{2\ell-1},i)})_{i>k_{2\ell-1}}$ satisfy $d(z_i,Z_i)<{\varepsilon}2^{-\ell}$ for all $i>k_{2\ell-1}$. By repeated applications of our preliminary observation we can find a full subtree $(x_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ of $(z_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ and a weakly null even tree $(y_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ such that $||x_\alpha-y_\alpha||<2(1+C){\varepsilon}2^{-\ell}$ for all $\ell\in{\mathbb{N}}$ and $\alpha=(k_1,\dots,k_{2\ell})\in T_\infty^{\textrm{even}}$. Since no branch of $(x_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ is in $\overline{A_{5C{\varepsilon}}}$, it follows that no branch of $(y_\alpha)_{\alpha\in T_\infty^{\textrm{even}}}$ is in $\overline{A_{C{\varepsilon}}}$. Thus $(c)$ fails. We will be applying Proposition \[P1\] for the case $A=\{(n_i,x_i)_{i=1}^\infty \,| (v_{n_i}) \textrm{ dominates } (x_i)\}$ where $(v_i)$ is a 1-unconditional basic sequence. We will also be repeatedly applying the technique of blocking FDDs. For this reason it is important that properties of $\bar{\delta}$-skipped blocks are preserved by blockings. This follows at once from the following simple observation: Assume that $(E_i)$ is an FDD with projection constant $K$, and $(H_i)$ is a blocking of $(E_i)$. Then a $\bar{\delta}$-skipped block of $(H_i)$ is a $2K\bar{\delta}$-skipped block of $(E_i)$. We will be concerned with a space $X$ which satisfies subsequential $V$-upper tree estimates. However the nature of our proofs require us to work with $X^*$ as well. This is because some of the blocking techniques which we use depend on the FDD being boundedly complete. Before stating a duality result on upper tree estimates, we need the following definition: A basic sequence $V=(v_i)$ is [*$C$-right dominant* ]{}(respectively, *$C$-left-dominant*) if for all sequences $m_1{\!<\!}m_2{\!<\!}\dots$ and $n_1{\!<\!}n_2{\!<\!}\dots$ of positive integers with $m_i{\!\leq\!}n_i$ for all $i{\!\in\!}{\mathbb{N}}$ we have that $(v_{m_i})$ is $C$-dominated by (respectively, $C$-dominates) $(v_{n_i})$. We say that $(v_i)$ is *right-dominant* or *left-dominant* if for some $C{\!\geq\!}1$ it is $C$-right-dominant or $C$-left-dominant, respectively. \[L3\] Let $X$ be a Banach space with separable dual, and let $V=(v_i)$ be a normalized, 1-unconditional, right dominant basis. If $X$ satisfies subsequential $V$-upper tree estimates, then $X^*$ satisfies subsequential $V^*$-lower $w^*$ tree estimates. $X$ has separable dual, so by [@DFJP Corollary 8] there exists a space $Z$ with a shrinking and bimonotone FDD $(F_i)$ for which there is a quotient map $Q:Z\rightarrow X$. After renorming $X$ we may assume that it has the quotient norm $||x||=\inf_{Qy=x}||y||$ for all $x\in X$. This gives that $Q^*$ is an isometric embedding of $X^*$ into $Z^*$. Furthermore, $(F^*_i)$ is a boundedly complete FDD for $Z^*$ as $(F_i)$ is shrinking. We next show that if $(x_i)\subset S_{X^*}$ is $w^*$ null, then there is a subsequence $(x'_i)$ of $(x_i)$ and a weakly null sequence $(y_i)\subset S_X$ such that $x'_i(y_i)>\frac34$ for all $i\in{\mathbb{N}}$. We have $(Q^*x_i)$ is $w^*$ null in $Z^*$ as $Q^*$ is $w^*$ to $w^*$ continuous. Hence there is a subsequence $(x'_i)$ of $(x_i)$ such that $||P^{F^*}_{[1,i)}Q^*x'_i||

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*a + 5*c - 848. Is 42 a factor of a? False Let s(r) = -3*r - 5. Suppose 0 = 3*z - 9 - 39. Let t = 10 - z. Is 8 a factor of s(t)? False Let z(v) = v**3 + 25*v**2 - 117*v - 11. Is z(-26) a multiple of 5? True Suppose 12*q = -12013 + 31597. Is 16 a factor of q? True Let r(v) be the first derivative of -1/3*v**3 - 5*v**2 - 4 + 0*v. Is 7 a factor of r(-7)? True Let k be (-27)/(-6)*16/(-12). Let m = -6 - k. Does 11 divide (-1 - m)/(13/(-286))? True Suppose 0 = 3*j + 2*i - 11 - 5, -3*j = -5*i - 23. Let s(y) = -y**3 + 10*y**2 - 11*y - 13. Is 13 a factor of s(j)? True Suppose 4*p - 1055 - 1038 = -f, 4*f = 4*p + 8272. Is f a multiple of 48? False Let f(q) = 8*q**2 - 4*q - 2. Let r be f(2). Let c be (4/(-5))/(r/(-55)). Suppose 3*t + c*t + 4*x - 212 = 0, 0 = 4*t - 3*x - 182. Is t a multiple of 13? False Let h(s) = -s**3 - 7*s**2 + 7*s - 7. Let l(c) = c**3 + c**2 - 2*c + 4. Let f be l(-3). Let o be h(f). Is 1/(-2 + o) - -25 a multiple of 12? True Let q = 23 + 14. Let g = 5 + q. Is g a multiple of 14? True Let s = -12 - -15. Let h(k) = 5*k**2 - k - 6. Is 6 a factor of h(s)? True Let y = 283 - 104. Suppose b - 90 = 5*f, -3*b + 449 = 5*f + y. Does 22 divide b? False Suppose 3*p - 18 = -4*j, -2*p + 12 = -0*p + 5*j. Suppose -p*h = -h - 240. Suppose z + z = h. Is z a multiple of 12? True Suppose -3*n + 6*n - 183 = 0. Let k = -42 + n. Is k a multiple of 19? True Let d = 7 - -6. Let g(z) = z**3 - 12*z**2 + 14*z - 10. Is g(d) a multiple of 46? False Let c(r) = r**3 + 4*r**2 + 2*r. Let h be c(-3). Suppose 0*u + h*u - 21 = 0. Suppose -607 + 110 = -u*m. Is 20 a factor of m? False Suppose 0 = 3*u - 3*o - 15, -5*u - 5*o = -2*o - 17. Suppose 0 = y - 5*m - 1, -5*y - 23 = u*m + 30. Does 9 divide (0 + (-1 - 0))*y? True Let s be (1 - 0)/((-5)/(-675)). Does 10 divide 4/(s/66 - 2)? False Let h = 0 + -9. Let m(j) = j**2 + 6*j + 18. Does 21 divide m(h)? False Suppose 0 = 2*r + 2, -4*r - 2 - 4 = x. Let m(y) = -y**3 + 2*y + 2. Is 6 a factor of m(x)? True Let l = 7 - 5. Suppose l*k = -k + 114. Is k a multiple of 8? False Suppose g - 795 = 1266. Is 21 a factor of g? False Let k(f) = 47*f + 5. Let b(u) = 41*u. Let r(v) = 42*v + 1. Let o(i) = 5*b(i) - 6*r(i). Let x(a) = -4*k(a) - 3*o(a). Does 23 divide x(-1)? False Suppose 8 = -3*k + 7*k. Suppose 5*q + k - 27 = 0. Suppose 0 = -q*x - 0*x + 45. Is x a multiple of 9? True Let f(s) = 16*s**2 + 25*s + 154. Does 4 divide f(-5)? False Let g be (16/10)/((-4)/10). Let t be g/(-3)*(-90)/20. Does 2 divide t/8 - (-253)/44? False Let v(s) = -s + 9. Let q be v(14). Let f = q + 31. Is 13 a factor of f? True Suppose -4*y = -2*y - 88. Let a = y - -177. Is a a multiple of 11? False Let t(h) = 141*h**3 - h**2 + 4*h - 4. Does 14 divide t(1)? True Suppose 14 = 2*s + 4*q, 4*s - 3*q - 21 = -4. Suppose s*i - 20 = 30. Suppose -2*b = -0*b - i. Is b even? False Let i(t) = -t**2 - 5*t - 4. Let k be i(-3). Suppose v = 4*a + 22, -k*a = -v - a + 13. Suppose -v = x - 3*x. Is 4 a factor of x? False Let s = -2546 - -3622. Suppose s + 1304 = 10*d. Is 9 a factor of d? False Let v(i) = 2*i. Let n be v(1). Suppose 3*b = 5*b - 8. Suppose -b*h + 88 = -2*z, 121 = 5*h + z + n*z. Is h a multiple of 15? False Suppose 5*y - 5631 - 2319 = 5*u, 0 = 5*y - 3*u - 7960. Does 55 divide y? True Suppose 2*u - 82 = -3*x + 43, 186 = 3*u + 4*x. Suppose -188 = -l - u. Suppose 0 = -2*y - 0*h - 2*h + l, -y = -3*h - 69. Does 33 divide y? True Suppose -4*p = -0*g - g + 16, -4*p = 4*g - 4. Suppose g*a = -a + 10. Suppose 3*y + a*y - 115 = 0. Is y a multiple of 3? False Let b = 626 - 381. Suppose 112 = 7*c - b. Does 51 divide c? True Let r = -122 + 312. Suppose -4*o + 122 = -r. Does 26 divide o? True Suppose 22*c = 19*c + 30. Let r be ((-6)/(-5))/(c/25). Suppose r*f - 26 = 2*f. Is f a multiple of 13? True Let i = -154 + 364. Is 20 a factor of (i/(-8))/((105/80)/(-7))? True Let t = -64 - -488. Suppose -5*u + j = -t, 2*j = 2*u - u - 83. Is 18 a factor of u? False Suppose 5*s + 3*k = 818, -2*s - 5*k = -5*s + 484. Does 8 divide s? False Let a(x) = x**2 - 4*x - 8. Let k be a(5). Does 38 divide (-1)/(-3)*579 + k? True Let l = -39 - -92. Let v(w) = 9*w - 2 + l*w**2 - 11*w + 1. Is 18 a factor of v(-1)? True Let i(o) = -15*o - 20. Let v(b) = 1. Let p(x) = i(x) + 30*v(x). Is 23 a factor of p(-7)? True Suppose -11*i + 1315 + 3173 = 0. Is 3 a factor of i? True Suppose 1082 = 4*c + 2*m, 5*c - 544 = 3*c - 4*m. Let b = c + -162. Does 18 divide b? True Suppose 4*q - 22 = -3*v, 4*q + 5

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de interne markt vind ik vier richtingen van beslissend belang. Ten eerste moet ervoor worden gezorgd dat de regelgeving voor de interne markt die al is aangenomen ten uitvoer wordt gelegd. Alle lidstaten moeten de regelgeving voor de interne markt tijdig en op transparante wijze invoeren, en de Commissie heeft tot taak zorgvuldig en consequent toe te zien op de tenuitvoerlegging daarvan. Ten tweede moet de neiging tot protectionisme worden beperkt. Bescherming zal slechts fragmentering van de Europese markt in de hand werken en ons totale concurrentievermogen verminderen. Ten derde moeten diverse transactiekosten die de vlotte werking van de Europese economie in de weg staan worden verminderd. Dit betreft niet alleen mechanismen zoals een doeltreffende, eenvoudige en buitengerechtelijke procedure voor het oplossen van geschillen, maar ook gebruiksvriendelijk grensoverschrijdend e-management met een functionerende elektronische uitwisseling van de benodigde informatie en documenten. De vierde richting is een grotere betrokkenheid van maatschappelijke groeperingen bij de vorming en uitvoering van beleid overeenkomstig de in het Verdrag van Lissabon vervatte beginselen. Tot slot, mijnheer de Voorzitter, wil ik graag alle schaduwrapporteurs en coördinatoren bedanken voor hun bijdrage en de doelmatige samenwerking die daaruit is voortgevloeid, die het ons vandaag hopelijk mogelijk zal maken resoluties over de interne markt met een overtuigende meerderheid aan te nemen, en de werkzaamheden voort te zetten die de laatste jaren zijn uitgevoerd voor de ontwikkeling van wetgeving die de interne markt werkelijk zal consolideren en er een instrument van zal maken om groei en banen in Europa te scheppen. António Fernando Correia De Campos rapporteur. - (PT) Mijnheer de Voorzitter, mijnheer Barnier, dames en heren, het Parlement heeft gereageerd op het verzoek van de Commissie betreffende de maatregelen die nodig zijn voor revitalisering van de interne markt middels het verslag waarover we vandaag debatteren en stemmen. Uit de negentien voorstellen in verband met de Single Market Act voor Europeanen, waarvoor ik rapporteur ben geweest, hebben we vijf prioriteiten vastgesteld volgens de criteria tastbaarheid en haalbaarheid binnen een relatief kort tijdsbestek. Ten eerste moeten we de mobiliteit van de Europese burgers vergroten middels wederzijdse erkenning van beroepskwalificaties, beroepsbewijzen, het Europese vaardighedenpaspoort en de regelmatige meting van mobiliteit binnen de EU. Ten tweede moeten we de grenscontroles op ingevoerde goederen uit derde landen verbeteren en een meerjarenactieplan opstellen voor markttoezicht en productveiligheid. Ten derde moet de termijn van de verordening over roaming worden verlengd tot juni 2015, met prijsplafonds voor roaming om de kosten voor burgers en bedrijven te verminderen. Ten vierde moeten we de toegang tot basisbankdiensten waarborgen en de transparantie en vergelijkbaarheid verbeteren. Ten vijfde moeten de obstakels worden weggenomen waarmee mobiele werknemers worden geconfronteerd, teneinde te zorgen voor de volledige overdraagbaarheid van hun pensioenrechten. Hierover waren we het al snel eens. Lastiger was het overeenstemming te bereiken over maatregelen om wat te doen aan de in het verslag-Monti genoemde moeheid van de Europeanen met betrekking tot de interne markt en om te komen tot de holistische, gezamenlijke benadering als antwoord op de behoeften en het wantrouwen van de burgers, die onmiskenbaar werden vastgesteld in het verslag-Grech dat in mei vorig jaar is goedgekeurd door dit Huis. Wij zijn stellig van mening dat het kunstmatig is het werk van het Parlement te verdelen in drie afzonderlijke verslagen, ondanks de inspanningen van de Commissie interne markt en consumentenbescherming om de analyses en acties te verenigen. Met de drie componenten - ondernemingen, Europeanen en bestuur - zal gelijktijdig vooruitgang moeten worden geboekt willen we kunnen zorgen voor een competitieve interne markt, met slimme, inclusieve en duurzame groei en waarin de Europeanen centraal staan. Wij zijn ons er verder van bewust dat het als gevolg van de proliferatie van initiatieven van de Commissie op dit gebied, samen met Europa 2020, het industriebeleid en het Europa van de innovatie, niet meer goed duidelijk is waar de revitalisering in feite voor is bedoeld, namelijk dat we het idee van een interne markt niet alleen vriendelijker maar ook aantrekkelijker maken voor de Europeanen. Consensus, mijnheer de Voorzitter, dames en heren, was het lastigst te bereiken over twee kwesties. De eerste betreft de eerbiediging van sociale waarden en rechten. Leden ter rechterzijde en van de Fractie Alliantie van Liberalen en Democraten voor Europa aanvaardden slechts schoorvoetend dat het noodzakelijk is de sociale rechten van de Europeanen permanent te waarborgen om hen te behoeden voor de gevolgen van marktoverwegingen in toekomstige wetgeving. We betreuren in het bijzonder dat een verwijzing naar de herziening van de richtlijn betreffende de terbeschikkingstelling van werknemers niet is aanvaard als prioriteit. De tweede kwestie betreft de waarborging van maatschappelijke diensten van algemeen economisch belang. Op dit punt beoogden we te voorkomen dat de activiteiten van die diensten inhoudelijk onderworpen zouden worden aan louter marktoverwegingen of in ieder geval dat het mogelijk zou zijn openbare maatschappelijke diensten om te vormen tot particuliere monopoliën of oligopoliën op zulke gebieden als watervoorziening, stadsvervoer, onderwijs, gezondheid en sociale dienstverlening. Hoewel de invoering van concurrrentiegericht beheer en internemarktmechanismen in die diensten nuttig kan blijken, zullen de sociale waarden die samengaan met universele toegang moeten worden gewaarborgd, aangezien de beginselen van solidariteit in dergelijke gevallen zwaarder wegen dan louter marktoverwegingen. Op dit punt ondervonden we verzet van de fracties ter rechterzijde in dit Huis tegen de aanvaarding van Europese wetgeving over dit onderwerp en het enige waarmee zij instemden was dat de Commissie "alle mogelijke opties moet aanwenden, in overeenstemming met artikel 14 [en] Protocol 26” van het Verdrag. De fractie waartoe ik behoor, heeft zich onthouden van de eindstemming over de drie verslagen in de commissie, aangezien er geen vooruitgang was geboekt met de sociale dimensie van de interne markt. Na de stemming in de commissie zijn er echter wel enkele positieve punten opgenomen waarmee het verslag aanzienlijk is verbeterd. Er is overeenstemming bereikt via een reeks compromissen, waarbij de definitieve amendementen werden onderschreven door de belangrijkste fracties en er geen winnaars of verliezers waren. Alle fracties hebben bijgedragen tot het e

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a felony conviction. (McKannay v. Horton, supra, 151 Cal. at p. 720.) Disqualification is a civil disability. (Helena Rubenstein Internat. v. Younger, supra, 71 Cal. App.3d at p. 418.) Accordingly, Carpenter's appeal does not stay his removal from office. D We are aware of the decision in McCormick v. United States, supra, 500 U.S. ___, which may or may not affect Carpenter's judgment on appeal. Carpenter's personal tragedy would certainly be compounded were the *1431 judgment set aside.[7] We emphasize the question of Carpenter's entitlement to office upon reversal is not before us and is not addressed here. DISPOSITION The petition is denied. Work, Acting P.J., and Nares, J., concurred. NOTES [1] Pursuant to California Rules of Court, rule 976.1, this opinion is certified for publication with the exception of part I. [2] The petition was originally filed in the Supreme Court. By order dated April 23, 1991, the Supreme Court transferred the matter here. [3] Matthew Fong is the son of March Fong Eu. Fong, as real party in interest, and the Republican Party, as amicus curiae, oppose the petition on identical grounds. For simplicity, we group the opposition as "respondents." [4] Amended by order on May 9, 1991. [5] All statutory references are to the Government Code unless otherwise specified. [*] See footnote 1, ante, page 1422. [7] Such a scenario is not without precedent. Lieutenant Governor of California Ed Reinecke was found guilty of perjury (18 U.S.C. § 1621) by a jury in the United States District Court for the District of Columbia. His conviction was reversed on appeal. (United States v. Reinecke (D.C. Cir.1975) 524 F.2d 435, 440 [173 App.D.C. 274].) Jinze Jinze () is a town in Qingpu District of Shanghai, China. As of the 2017 census it had a population of 60,800 and an area of . The town is bordered by two provinces, namely Zhejiang and Jiangsu. With convenient land and water transportation, it is an important transport hub linking Shanghai, Zhejiang and Jiangsu. It is surrounded by the towns of Shenta, Zhouzhuang and Jinxi on the northwest, Liantang Town on the southeast, Zhujiajiao Town on the east, and the towns of Dingshan and Dashun on the southwest. Name Jinze, formerly known as "Bainingli" (). According to Chorography of Jiangnan (), the name derives from a farmer got a stone of the same colour as gold. History In 978, it used to be in the territory of Northern Song Empire (960–1127) under the jurisdiction of Huating County (). In 1279, the Yuan Empire (1271–1368) set up province system to maintain control of the vast region. Jinze under the jurisdiction of Songjiang Prefecture () of Zhejiang Province. In 1573, in the ruling of Wanli Emperor (1573–1620) of the Ming dynasty (1368–1644), Qingpu County was established. Jinze belonged to Qingpu County. In 1743, in the reign of Qianlong Emperor (1736–1795) of the Qing dynasty (1644–1911), four townships was founded, namely Haizhong Township (), Haishang Township (), Huazhong Township () and Huashang Township (), Jinze came under the jurisdiction of Huashang Township. In 1909, the Qingpu County was divided into 16 autonomous districts, Jinze was one of them. In 1912, after the establishment of the Republic of China, Jinze became a township. In 1929, the whole county was divided into 13 districts, Jinze was the Fifth District. In 1934, after the merger of districts, it belonged to the Fourth District. In February 1948, after the adjustment of administrative divisions, Jinze became a township. In July 1949, Qingpu County was divided into 8 districts, Jinze was one of them. In May 1957, Jinze Township was founded. In September 1958, it was renamed "Jinze People's Commune". In May 1986, it was upgraded to a town. In March 2004, the towns of Shangta () and Xicen () were merged into the town. Administrative division As of 2017, the town is divided into 5 communities and 30 villages: Jinxi Community () Jinyang Community () Xicen Community () Liansheng Community () Shangta Community () Xuli () Xinchi () Jinze () Yangwan () Dongxi () Jianguo () Jinyao () Xingang () Cenbo () Xicen () Santang () Yutian () Hezhu () Aiguo () Dongtian () Rentun () Tianshanzhuang () Gongdu () Qiansheng () Dianhu () Lianhu () Caibang () Dongxing () Wanggang () Shuangxiang () Nanxin () Chendong () Xuemi () Dianxi () Shagang () Geography The Dianshan Lake is located in the town, it is the largest freshwater lake in Shanghai. Jinze is in the subtropical oceanic monsoon climate zone and exhibits four distinct seasons. It has an average annual temperature of , total annual rainfall of , and a frost-free period of 247 days. Economy The local economy is primarily based upon aquaculture and local industry. The main aquatic products are crabs, turtles, eels, shrimps and various freshwater fish. Culture The Farmland and Mountain Folk Song () is a national-level intangible cultural heritage. Tourist attractions According to historical records, there had been "Six temples, a tower, thirteen archways and forty-two bridges" in the town, among which 21 old bridges survived till today. It is the only town that has so many old bridges in Shanghai, thus earning itself the accolade "the top Bridge Town of Jiangnan region". The five bridges spanning parallel over the river course in the vicinity of Xiatang Street in particular, were built respectively in the Song, Yuan, Ming and Qing dynasties (960–1911), so there was a saying "Bridges of four dynasties are stringed by one river". Of the five, Puji Bridge and Wan'an Bridge, built in the Southern Song dynasty (1127–1279), are the oldest stone arch bridges in Shanghai. The two being collectively known as the "Sister Bridges". Religion Yihao Temple () is a Buddhist temple in the town. It was originally built in the Southern Song dynasty (1127–1279) and renovated in the following dynasties, the temple had reached unprecedented heyday in the Yuan dynasty (1721–1368), overtaking Lingyin Temple and Chengtian Temple. Transportation The town is connected to two highways: National Highway G318 and G50 Shanghai–Chongqing Expressway. The main channel is the Taipu River (). Notable people Wang Dajue (), writer. K. K. Chen (), Chinese-American pharmacologist. Jiang Linhua (), sailing competitor. References Bibliography Category:Towns in Shanghai Category:Divisions of Qingpu DistrictEffects of fasting and refeeding on insulin binding to liver plasma membranes and hepatocytes from normal rats. The effect of acute and chronic starvation on insulin binding to liver cells and liver cell membranes was studied in normal rats. A short-term (1 day) fasting period did not induce significant changes in insulin binding to liver plasma membranes in spite of the hypoinsulinemia present in the rats, as compared with normo-insulinemic fed controls. Longer periods of fasting (2 and 4 days) elicited an increase in insulin binding to liver membranes that was due to an increase in the number of insulin receptors rather than to changes in affinity. All groups of membranes were similar with respect to the rates of association and dissociation of hormone, degree of negative cooperativity and extents of both hormone and receptor inactivation. The fasting-induced increase of insulin binding was not a consequence of the methodological procedure for membrane isolation since the same conclusions were obtained when intact hepatocytes were used. Refeeding of fasted animals resulted in a decrease of insulin binding together with an increase of insulinemia towards the fed control values. These results suggest that the number of insulin receptors is inversely related to the circulating levels of the hormone and support the hypothesis of insulin regulating its own receptor.MERS-CoV, South Korea, Cases (7 June 2015) As of early this morning (presumably including cases up to Sunday 7th June), there are now 87 cases of MERS-CoV infection in South Korea, with 6 deaths. The updated list of cases is at the Flutrackers forum here. There is also a list of 24 hospitals that is managing or had been visited by patients with MERS, although some inaccuracies have been noted in the list. There appears to be at least one other “super-spreader”, a 40-year-old man who had been on the same ward as the

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� kết nối. Chắc hẳn bạn biết rõ tính huống khi mà bạn nhận được đánh giá từ bà chủ của mình, và bà ấy chỉ cho bạn 37 thứ bạn làm thực sự tốt, và một thứ -- một cơ hội để làm tốt hơn? (Cười lớn) iw: כי אני מתעניינת בכמה נושאים מאד מבולגנים. אך יש לי רצון להצליח להפוך אותם ללא מבולגנים. אני רוצה להבין אותם. אני רוצה להצליח לפרוץ אל אותם דברים שברור לי שהם חשובים ולהציג את החוקיות שלהם לעיני כל. והמקום שהתחלתי ממנו היה הקשר. שכן, בנקודה שבה אתם עוסקים בעבודה סוציאלית כ-10 שנים, מה שאתם מבינים הוא שקשר הוא הסיבה שבגללה אנו כאן. הוא מה שמעניק מטרה ומשמעות לחיינו. זהו הדבר המהותי ביותר. זה לא משנה אם אתם מדברים עם אנשים שעובדים כפעילים חברתיים או בבריאות הנפש או בנושאי התעללות והזנחה, מה שאנו יודעים הוא שקשר, היכולת להרגיש קשור, היא -- נוירוביולוגית, זה האופן בו אנו מחווטים -- זו הסיבה שבגללה אנו כאן. ואני חשבתי - יודעים מה, אני אתחיל עם קשרים. אם כן, אתם מכירים את המצב הזה שאתם מקבלים הערכה מהמעבידה שלכם, והיא אומרת 37 דברים שבהם אתם ממש מדהימים, ודבר אחד שהוא - "הזדמנות לצמיחה". (צחוק) Lithuanian: nes mane domina nešvarūs dalykai. Tačiau noriu sugebėti juos sutvarkyti. Aš noriu juos suprasti. Noriu įsilaužti į tuos dalykus, kurie yra svarbūs ir pateikti kodą matomą visiems. Taigi, aš pradėjau nuo ryšio. Nes, kai jau 10 metų esi socialinis darbuotojas, suvoki tai, kad būtent ryšio dėka mes visi esame čia. Tai suteikia tikslą ir prasmę mūsų gyvenimams. Štai kas tai yra. Ir visai nesvarbu, ar tu kalbi su žmonėmis, kurie dirba socialinio teisingumo, ar psichinės sveikatos srityje, su patyrusiais prievartą, su apleistais – mes žinome, kad tas ryšys, tas gebėjimas jaustis susijusiam, yra todėl, kad mes taip sustyguoti neurobiologiškai - ir dėl to esame čia. Taigi pamaniau, žinote ką - pradėsiu nuo ryšio. Ko gero, žinote tokią situaciją, kai viršininkė vertina jūsų darbą ir susako 37 dalykus, kuriuos darote tiesiog baisiai ir vieną dalyką - kaip galimybę augti? (Juokiasi) Norwegian: fordi eg er interessert i kinkige tema. Men eg har lyst å vere i stand til å gjere dei ikkje-kinkige. Eg ønskjer å forstå dei. Eg vil hakke laus på desse tinga eg veit er viktige og løyse koden slik at alle andre ser det. Så eg starta med tilknyting. Fordi når du har vore sosionom i ti år skjønar du at tilknyting er grunnen til at me er her. Det er det som gir liva våre mål og meining. Det er det alt handlar om. Det betyr ikkje noko om du snakkar med menneske som jobbar med sosial rettferd, mental helse og misbruk og forsøming, det me veit er at tilknyting, evna til å føle tilknyting er -- den nevrobiologiske måten me er skrudd saman på -- det er grunnen til at me er her. Så eg tenkte: veit du kva, eg startar med tilknyting. Og du kjenner situasjonen kor du blir evaluert av sjefen din, og ho fortel deg 37 ting du gjer på ein framifrå måte og ein ting -- ein "muligheit for vekst?" (Latter) Bulgarian: защото се интересувам от объркани теми. Но искам да мога да ги подредя. Искам да ги разбера. Искам да проникна в тези неща, за които знам, че са важни и да ги направя разбираеми за всички. Това, с което започнах, беше връзката. Когато имаш около 10 години стаж като социален работник разбираш, че връзката е това, заради което сме тук. Тя дава причина и значение в нашият живот. Това е всичко. Няма значение дали говорите за хора, които работят по теми като социална справедливост, ментално здраве, малтретиране и пренебрегване, това, което знаем е, че връзката, способността да се чувстваме свързани, невробиологично е начинът, по който ние се обединяваме - затова сме тук. Помислих си, че ще започна с връзка. Позната ви е ситуацията, в която получавате оценка от

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s**t. Our vehicle ecellerates to 88 MPH in 2 seconds, as we must go Back to the Studio! We arrive back to the studio as the artists appear overhead on screens congratulating us for surviving and that we can come back any time! We then exit our vehicles and head out back to Production Central. The Vagabond Adventure Tours is the leading touring company in the world offering tours that are fun, exciting and yes even a little educational! But they are not your typical adventure company offering Safari trips in Africa or white water rafting on the Amazon, they offer Disaster Tours! The Vagabond Adventure Tours offers disaster tours all over the world getting there adventurers closer to the event than any other disaster touring country could. They have had tours to New Orleans right after Hurricane Katrina hit, brought adventurers to the 2010 eruption of Eyjafjallajökull volcano in Iceland, and still offers adventurers a chance to get closer to the biggest nuclear power plant disaster at Chernobyl. There newest offering to adventurers is a chance to see and experience an ongoing flooding of a whole American town. Willimantic is a large town located in California that just experienced an earthquake that partially damaged a dam uphill from them. The earthquake also damaged the Kravet Nuclear Power Plant near to them but The Nuclear Regulatory Commission (NRC) has stated that has stated that the damage to the power plant was minimal and radiation leaks have been contained. The 90% of the inhabitants of Willimantic are feared dead due to the sudden break of the dam and the flooding it caused. The Vagabond Adventure Tours has bought an abandoned sporting goods store and made that the meeting place for their new tour. The Vagabond boat tour will get up close and personal experience of how destructive Mother Nature can be. This boat tour will go from leisurely, to thrilling, to chilling, to downright terrifying! Queue/Building: The area around the ride will look like an abandoned American town with store fronts and houses. The queue and the ride entrance will be a sporting’s good shop that has been abandoned but still intake and next to water. Inside the shop it will look like people who were in there at the time of the earthquake and the flooding just dropped everything and left. The T.V.’s have been left on also to MSNBC and The Weather Channel and other Universal news organizations covering this whole event and then describing to people that there are tours going to the town. Ride: The ride starts in the middle of Main Street Willimantic and the ride starts at a leisurely pace through some of the most prominent areas of Willimantic including government buildings and the town square. The boats also have speakers in them with Alex as the host of the tour explaining details of the town and giving you tips on what to expect. Then the tour takes it first drastic tour. The first tremor hits the town. The tremor is actually more severe than the initial earthquake that hit the town. You hear Alex scream because the dam breaks and your leisurely tour take a wilder ride! Because the dam is uphill to the town the water now comes streaming down the hill and towards you. The boat bucks and twists the boat is straight and then backwards. The boat takes a wild plunge down some steep and long hills. There will be 3 main drops the first is a 30ft drop, the second will also be a 30ft drop but backwards and the last drop is a 55ft drop reaching speeds of 42mph! After the second drop where you go backwards you see the first signs of life. You see in the distance a family of 4, 2 adults and 2 kids. Then after the third and final drop you see more and they are starting to get close. Alex mentions that the other tour boats are seeing more and more but the only thing they can see clearly is a green glow emanating from their eyes. Alex is coordinating effort with other tour guides from The Vagabond Adventure Tours to see if they can get them all together and get them out of Willimantic. She starts asking each where they are and when she asks for Jason he doesn’t answer and they presume he’s busy. Well they are right he is busy! The boat then turns a corner and they see 4 people huddled close together with someone lying on the ground Alex believes it is someone that is hurt and they should stop to assist. When they stop the people turn to the boat their green eyes glowing brighter, you see the skin hanging off their faces, blotchy blood corpse like people. In the middle of the group lying on the ground is a body with a shirt just like The Vagabond Adventure Tours guides wear and he is being torn and eaten by these people! They look up again and start moaning lifting their arms and hands towards you and then get up and start walking towards the docked boat. Yes this is also a Zombie ride! Apparently the nuclear reactor leak was not as minimal as first thought and the people that were feared “missing and dead” were not actually “missing” but here all along. Alex screams and throws the throttle of the boat into full and gets away from this group. All along the edge of the “river” or “street” there are Zombies chasing or walking towards the boat. You can hear the moans all over the place and all over the boat. Alex thinks that if they go down a certain way they can find a way out. Alex sends the boat down another path in which the buildings get closer and closer to the boat. Alex thinks that because the buildings are close the Zombies can’t get to them. Well Alex doesn’t take into the account that the Zombies are in the buildings! They start breaking through windows and reaching out to the boats. One even comes close to dropping into the boat! Well finally Alex gets away from the buildings and says if they can get into the Hassler Tunnel, a tunnel system that connects to State Route 20. The boat finally gets into the tunnel and its dark but you can’t hear any moans so there’s got to be no one in there right? You first see green eyes down in the distance in the tunnel, then in the back of the boat, then on the sides, and then you start seeing instead of one pair of eyes you start seeing dozens of them all around the boat and they are getting closer. Then you hear the moans again echoing all over the tunnel. Fortunately the lights are out and you can’t see them, well that change’s. The fluorescent flood lights start to flicker and each flicker you see them. You see them snarling, walking towards the boats, you see some of them falling into the water and standing and still coming towards you. And each blinding flash you only see them for a split second and each one is more terrifying then the next. At one point during one of the flashes a camera takes a picture of you. Alex decides that they have had enough with safety and guns the engines to the boat as hard as they can to get out of the deathtrap of Hassler’s Tunnel to get back to the sporting goods base. Exit/Base: You finally get back to Base and realize it changed a bit instead of the sporting goods store you saw before well the building hasn’t changed but the inside has. The army and CDC are here and inspecting everyone that has come of the boat making sure nobody is infected! Here are also video screens showing the pictures that were taken during Hassler’s Tunnel. Is it over? After seeing the photos and possibly buying them everyone is ushered into a final hallway to exit in the hallway they are ordered to wait for another boat to come and that person leaves. The hallway is white with other corridors and doors the end of each. On one side of the wall is a mirror. While waiting you hear a roar, then the floor shakes and the lights go out! You were hit with a second tremor. Like before you see the green glowing eyes, hear the moans, and they are all around down each corridor and the door in front and behind you are locked! You hear over the loud speakers that they are working to get you out and just wait and that they are working on the lights. They again flicker and you actually see them getting closer to you, the mirror turns out to be a two way mirror and Zombies are seen and heard banging on the glass. Finally the lights go fully out and the glowing eyes move back and finally fad away with the lights finally turning on for good. The doors open to the exit and as guests leave the hallway they are immediately met with a large tank sitting in front of the door with the barrel of the tank pointing directly at the door! Technical Stuff: The ride will be a Flume ride using the same boats as the Jurassic Park: The Ride at IOA and will be a good complement to it. The boats and the track will be adapted to go backwards as well as forward. The ride will both feature audio animatronics and live performers. There will be more live performers during Halloween in which Hassler’s Tunnel and the Exit Hallway scenes will be even more terrifying! I didn’t include pictures of the Zombies to get the website family friendly and also we all know they look like! Also what make my Zombies unique are the green glowing eyes which gets people to assume that the nuclear power plant is the cause. And yes I do realize that Universal and IOA will have flume rides but WDW has two also and are both very popular.

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MultiLayer: 0 MultiTake: 0 Hidden: "True" Shading: Y Culling: "CullingOff" TypeFlags: "Camera" GeometryVersion: 124 Position: 0.000000,-4000.000000,0.000000 Up: 0,0,-1 LookAt: 0,0,0 ShowInfoOnMoving: 1 ShowAudio: 0 AudioColor: 0,1,0 CameraOrthoZoom: 1 } Model: "Model::Producer Front", "Camera" { Version: 232 Properties60: { Property: "QuaternionInterpolate", "bool", "",0 Property: "Visibility", "Visibility", "A+",1 Property: "Lcl Translation", "Lcl Translation", "A+",0.000000000000000,0.000000000000000,4000.000000000000000 Property: "Lcl Rotation", "Lcl Rotation", "A+",0.000000000000000,0.000000000000000,0.000000000000000 Property: "Lcl Scaling", "Lcl Scaling", "A+",1.000000000000000,1.000000000000000,1.000000000000000 Property: "RotationOffset", "Vector3D", "",0,0,0 Property: "RotationPivot", "Vector3D", "",0,0,0 Property: "ScalingOffset", "Vector3D", "",0,0,0 Property: "ScalingPivot", "Vector3D", "",0,0,0 Property: "TranslationActive", "bool", "",0 Property: "TranslationMin", 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akhia> can you type: file Urb* <alakhia> that should tell you what kind of file you have <Guest31841> ioUrbanTerror.i386: ELF 32-bit LSB executable, Intel 80386, version 1 (SYSV), dynamically linked (uses shared libs), for GNU/Linux 2.2.0, not stripped <alakhia> great ... it is an application <alakhia> so, now type: ./Urban* <Guest31841> still denied <alakhia> what is the exact message? <Guest31841> bash: ./ioUrbanTerror.i386: Permission denied <little> Barridus: Aare you still there? <alakhia> is your userid nick? <Guest31841> yep <alakhia> indulge me and run: chmod a+x Urban* <Guest31841> same thing. denied <alakhia> er, i mean: chmod a+x ioUrban* <tron2000> anyone on here using bitchx as their client <Guest31841> yep did that <alakhia> that is strange ... i'm not sure why you can't access a file that you own <Guest31841> same here.... I can access any other files on the drive. Just cant run that i386 <alakhia> hmmm, is it possible that you mounted the drive using noexec flag? <Guest31841> hmmm <Guest31841> will check <alakhia> do: grep noexec /proc/mounts <Barridus> is it possible to reset permissions? (those popup password prompts that i previously told to remember the permission forever) <alakhia> Barridus: which popup was this? <Guest31841> it does have the noexec flag. weird... shouldnt use mountmanager prog :/ <Barridus> alakhia you know, the prompts for passwords when you make a system change <Barridus> there's radio buttons that say "remember this permission foreveR" or something. i want to reset/clear that <little> barridus: If you open kwallet by typing kwalletmanager in a terminal window, then you can go into the configuration menu and change the settings. <alakhia> ok, mystery solved ... if you copy that file somewhere else, chmod it, then it will work <alakhia> or just remount with noexec off <Guest31841> thanks alakhia. super help <Guest31841> works <alakhia> cool <pondus_> hej <Barridus> little, i'm not sure if that's what i'm looking to do <Barridus> i could have sworn i used to get popups for passwords when adding removing packages in kpackagekit, etc <Barridus> i don't see anything in kwalletmanager for that <alakhia> Barridus: try looking at: ~/.kde/share/config/kwalletrc <alakhia> in case you are brave enough to modify it directly and remove things from "Auto Allow" section <little> Usually if a program asks if you'd like it to remember a password, it kicks in the kwallet automatically. Have you tried going into kpackagekit and having it remember a password? <Barridus> alakhia, hmmm i assume i want to remove things from [Auto Allow] <Barridus> little, yes i believe i did that. want to remove it :) <alakhia> Barridus: be careful .. and make a backup in case things go bad <Barridus> yeah, always ;) <alakhia> also i'm not sure how you can tell kwallet to read the new file ... you might need to log out and back in perhaps? <Barridus> probably <little> Barridus: Ah, that should be possible under the configuration menu, isn't it? <Barridus> i don't see anything in kwalletmanager for kpackagekit specifically <little> Barridus: Did you look in the Access Control tab and expand the listing? <Barridus> mostly just networking related things (KRDC, Kopete, Network Manager, twitter, etc) <Barridus> tab? <Barridus> tab in what, little? i see none in kwalletmanager <little> Barridus: In my kwalletmanager if I go into the Settings menu and then choose Configure Kwallet, there is an Access Control tab with a listing of the programs that use Kwallet. <Barridus> ahhh, ok <Barridus> KDE Control Module? <little> Barridus: That I'm not sure of. In that tab I have kdewallet with a plus next to it. If I click the plus, I get a listing of the programs that use the wallet. Is that where KDE Control Module is? <Barridus> KDE Daemon perhaps? <Barridus> yes <little> Barridus: Someone in the #ubuntu-devel channel might know. <Barridus> hmmm <little> Barridus: I suppose it wouldn't do any harm to remove any entry in the wallet, because it would simply prompt you to add it again if anything needs a password and hasn't got it. (: <Barridus> yeah i suppose <Barridus> heh * little likes to occasionally get yelled at by her computer. (: <Barridus> hmm, no effect. lemme log out and back in <little> Barridus: Okay, crossing fingers. <little> Barridus: How is it going? <pawel> hey guys i managed to run skype under pulseaudio in kubuntu but i have huge trouble with another application that isnt PA compatible. do u know any solution that might help? is there a alsa wrapper that would "fool" the app? <little> No idea, sorry! <rysh> Hi, anybody using kde4.3-beta1 on jaunty?? <rysh> Seems the plasma-widget "system Monitor - network settings" can not find any network interface ... <rysh> anyone who also found this ? ... and maybe have a solution? <vadi01> hi guys. i need to ask how the new kubuntu 9.0.3 is with kde? i ask cause the previos release honestly was terrible <vadi01> and i had to shift my os <vadi01> is rock solid? <vadi01> cause am thinking of downloading and installing it <Num83rGuy> I have the same problem with the net mon. <Num83rGuy> It'll get fixed. <vadi01> Num83rGuy: you refering to my question? <Pondus2> hi...dos anyone know about xbins <vadi01> net mon is buggy from kde itself <Num83rGuy> Nah, it was rysh I was refering to. :) <perseid> Problems with the net mon? As in network access going away randomly? <rysh> Num83rGuy: aha, thanks for replying ... so it seems i am not the only one with this problem <vadi01> Num83rGuy: ok. anyway it seems that kubuntu developers also have a prob with net mon <vadi01> Num83rGuy: is gnomenetwork monitor recommended to be used meanwhile? <vadi01> rysh: what happens? <Num83rGuy> No it doesn't go away randomly just the net mon plasmoid can't find the net interface to monitor. <rysh> I know kde4.3 is BETA and for me it is not a real problem ... just wanted to know if there was a solution available ... <rysh> i am using kde 4.3 beta1 .... and the plasma widget "System Monitor - Network Settings" is not seeing any interface <vadi01> well in fedora-kde its the same prob. <Num83rGuy> Yup thats life in beta. <vadi01> so the developers are using gnome network monitor instead. is this possible in kubuntu? <rysh> Num83rGuy: :-) ... doesn't matter ... kde4.3 beta1 still looks nice ... even without this plsma-widget <vadi01> and it sure does not look like there will be a solution anytime soon as in this month <perseid> I installed wicd for networking. <Num83rGuy> The network manager in kde works great it's the little in-out graph that doesn't work in 4.3 beta. <vadi01> rysh: hmmmm kde 4.3.... how buggy have you found it to be? <rysh> Well first it ddi not really install smoothly ... many errors that it wanted to overwrite files from other packages <rysh> so i used a lot of dpkg --force overwrite /var/xxx/xxxx

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When he was invited to return to Albert's legacy for the Namatjira Project, "at first I was like, no, I can't do this any more. I just gave up doing Namatjira, in the end, because of the realisation of what the government's not been doing for us, and I just wish there was a resolution. There's still that question to this day, how can we resolve it? How can we resolve the whole Namatjira legacy?" Namatjira Project doesn't answer the question, but neither does it end on a tragic note. While the mission to win back copyright continues, the film makes apparent another aspect of Albert's legacy that lives on: his family have continued to paint in his distinct style, and a new generation of young artists is picking up brushes now. "His DNA keeps on through the younger generations," says Jamieson, "and new generations are what matter." Namatjira Project premieres August 5 at the Melbourne International Film Festival. miff.com.auPages Monday, May 17, 2010 What A WOW Monday! I usually don't care for Mondays. Mondays are late start days for my teenage son and it just messes up my whole morning schedule. But today is a WOW Monday! When I first came across Words of Wisdom I was so excited to see what Sandy and Pam were bringing to the blog world. There are a lot of great blogs out there that need to be seen and that is exactly what Pam and Sandy are doing...exposing wonderful blogs (so I feel incredibly privileged that I was chosen on this Monday and my feelings of Mondays will forever be changed) :) I want to reach out to the world on being positive and share with them how being positive has helped me. I am not perfect and I am not "always" positive but I can say that positivity has brought me where I am today. I have had a roller coaster life since I can remember and I have memories going way back to when I was 3! So I can honestly say I know God has blessed me with positivity to help me survive and make it through this temporary life. I have recently rediscovered my passion for art and writing. I lost that for a while because I forgot who I am. I am still getting used to drawing again and am a slowly getting back into it. My biggest goal in this is to reach out to children and parents so that children can know early on how important it is to be positive. Thank you for visiting my page today from WOW and I hope you will enjoy what I have to say and by all means, if you can contribute, please do! Happy Monday! Please visit Pam and Sandy and read about all the wonderful blogs they have already exposed here at Words of WisdomThis invention relates to an adjustable fluid flow regulator, and in particular to an adjustable fluid flow regulator having a finite adjustment limit. Commercial and Residential gas appliances typically use natural gas or L. P. gas, which are delivered at different pressures. It is desirable to have equipment that can be converted for use with either type of gas, rather than equipment limited in use to just one type of gas. A number of attempts have been made to make an adjustable pressure regulator that is capable of operating within the pressure ranges typical for the two types of gas. Examples of these include Bauman, U.S. Pat. No. 3,747,629; Love, U.S. Pat. No. 4,718,448; Buezis, U.S. Pat. No. 5,435,343; Dalton, U.S. Pat. No. 6,173,775. Most of these devices employ a diaphragm for controlling a valve, a spring for biasing the diaphragm, and a means for varying the spring pressure to adjust the fluid flow regulator. While the prior adjustable fluid flow regulators are useful for the purposes described, there is still a need to reduce the risk of inadvertent adjustment above the pressure ranges typical for natural gas and L. P. gas, or the specified maximum pressures of the appliance manufacturer. The present invention relates to an adjustable fluid flow regulator construction that can be converted between two modes of operation, but which restricts accidental or inadvertent adjustment above a predetermined maximum limit. The regulator of the present invention comprises a casing having an inlet and an outlet, a diaphragm-operated valve, and a servo-regulator diaphragm. The servo-regulator diaphragm regulates the passage of a control gas pressure that is applied to one side of the diaphragm that operates the valve. The valve opens and closes as the diaphragm moves in response to pressure changes on either side of the diaphragm. By adjusting the servo-regulator diaphragm, the control gas pressure can be adjusted to control the opening of the valve. The adjustable fluid flow regulator further comprises a spring for applying pressure against the servo-regulator diaphragm to control the operation of the valve. A first screw and a second screw are both used to adjustably bias the spring against the servo-regulator diaphragm. The second screw, which engages the spring, is adjustably disposed within the first screw. Initially adjusting the regulator involves fully adjusting the first screw to a limit within the regulator, and subsequently adjusting the second screw until the predetermined maximum regulator setting is obtained. Once the maximum setting adjustment is made, the second screw may be restricted from further adjustment in the field by using a non-standard screw head not adjustable by the public, or by a means of covering the screw. Subsequent adjustment would be limited to the first screw and would not exceed the maximum regulator setting established by the limit.Review: EVGA GeForce GTX 670 FTW Power Consumption, Temperature and Noise We found the EVGA card to be slightly more hungry when playing Batman: Arkham City, but there's not a lot in it - the power characteristics of both factory-overclocked cards are similar. Here's where things get interesting. EVGA's GTX 670 FTW does well to keep the factory-overclocked card running below 80ºC under load - it's actually cooler than the stock-clocked reference design - but ASUS's custom-cooled GTX 670 DirectCU II TOP is in a different league all together. We see a similar pattern in our noise evaluation; the EVGA card isn't particularly loud and performs similarly to a reference GTX 680, but it isn't as quiet as ASUS's custom DirectCU II cooler.Although numerous genetic alterations have been causally linked to cancer development, many of the affected genes appear to fall into common cellular pathways. With the advent of technologies capable of assessing the expression of thousands of genes simultaneously, the potential now exists to "reverse- engineer" cancer-related signaling pathways by computer modeling. Towards this end, the objective of this proposal is to develop experimental methods and analysis tools to elucidate the components of signaling networks functionally altered during tumorigenesis. To achieve this goal, prototype pathway modeling algorithms will be tested in Phase I for their ability to detect known relationships among genes manipulated in experimental systems. Specifically, recombinant wildtype versions of genes frequently mutated in cancer development will be inducibly expressed in cell lines, and the resulting expression changes in endogenous genes will be monitored by hybridization to oligonucleotide arrays. Analogous studies will also be performed using cells in which individual genes have been deleted. The protein products of genes that demonstrate altered expression in such studies serve as candidate functional mediators of the ectopically expressed genes. The commercial goal of these studies is to develop broadly applicable tools to facilitate the rational identification of novel diagnostic markers, prognostic markers, and therapeutic targets. PROPOSED COMMERCIAL APPLICATION: We will develop experimental and analytical tools to reverse-engineer signal transduction networks from gene expression profiles. These tools will facilitate the rational identification of novel diagnostic markers and therapeutic targets. As such, they will enhance the sale of high-throughput expression analysis systems and pathway analysis software./* * Copyright 2017 The Apache Software Foundation. * * Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. */ package org.apache.storm.kafka.spout.subscription; import static org.mockito.Mockito.clearInvocations; import static org.mockito.Mockito.inOrder; import static org.mockito.Mockito.mock; import static org.mockito.Mockito.when; import java.util.Collections; import java.util.HashSet; import java.util.Set; import org.apache.kafka.clients.consumer.ConsumerRebalanceListener; import org.apache.kafka.clients.consumer.KafkaConsumer; import org.apache.kafka.common.TopicPartition; import org.apache.storm.kafka.spout.config.builder.SingleTopicKafkaSpoutConfiguration; import org.junit.Test; import org.mockito.InOrder; public class TopicAssignerTest { @Test public void testCanReassignPartitions() { Set<TopicPartition> onePartition = Collections.singleton(new TopicPartition

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: literature, the arts, sciences, philosophy, and the ongoing debate about the future of Marxism. It is fascinating to observe the extent to which she, who never knew her father, chose someone whose inner qualities uncannily resembled his. True, Modigliani, although a Socialist and supporter of Emanuele's causes, was never politically active. But he and Valdi had the same omnivorous intellectual curiosity, the same love for poetry, the same impulsive ability to jump into the middle of a losing fight, and the same gift for keeping up a false front. Speaking of his Resistance years Valdi wrote, "We were like actors wearing masks," performing a life-or-death drama in broad daylight before a public that did not know and would not have cared. Modigliani could have said the same. Valdi was also married to Hélène and had two young sons, Maxime and Alain. In wartime nothing like that stood in the way of people who were deeply in love. Desanti said that the relationship for Jeanne was "determinant, crucial." As for Valdi, he wrote, "Her rebellion was full of verve. The exuberance of her intelligence, her vivacity, her frankness and her charm bowled me over. I was seduced. Our union, begun in a moment of common danger, lasted for thirty years." That a life of high adventure is not only exhilarating but can bring out the very best in people is a truism that applied to Jeanne Modigliani in particular during the German occupation of France. François Vitrani, who became one of Valdi's pupils, called her a "grande Résistante," i.e., a model of courage and "unbelievable audacity." She and Valdi shared, not only the constant fear of being captured and tortured, but missions calling for resourcefulness and the ability to improvise. But the organization Vernant put together had mastered the art of creating forged papers that were persuasive enough to rescue Valdi several times. Similar documents were also used to free Jeanne from prison. She was arrested in October 1943 and released in January 1944. Glodek said, "During the liberation of Paris she was in the middle of things and always fearless." He recalled one day when they—meaning himself, Valdi, and Jeanne—had a rendez-vous on the Left Bank that required them to walk in front of a heavy German field battery, installed behind fortifications on the Place Saint-Michel. At the least sign of fear or haste the suspicious Germans might have opened fire. But Jeanne was magnificent. "She looked the Germans straight in the eye and calmly crossed the square, just like that," he said. Jeanne's defiance sometimes bordered on recklessness. Jean-Pierre Haillus tells the story about one time, during the German occupation, when she and Valdi happened to enter a restaurant full of members of the Gestapo. Jeanne took in the scene, then ordered from the menu. In a loud voice, she would have some "Résistance soup," or words to that effect. Valdi kicked her hard under the table and hustled her out of there. _Les Tribulations d'un idéologue,_ written in 1984 under his alias of Victor Leduc and recently reprinted, is a fascinating account of this French intellectual's Communist beliefs and his slow disenchantment as the truth about Stalin's repressive regime became clear. It was written partly to explain to a new generation how someone like himself, so hard to deceive, could have taken up the cause at great personal risk and continued to believe in its tenets until post-Stalinist revelations made such a belief impossible. At the same time it is a kind of admission that life spent in a clandestine world exacts a high personal price. Being with Jeanne on cloak-and-dagger missions during the war was one thing. Setting up life with Jeanne in a Paris apartment was something else. By 1946 Jeanne had divorced Mario Levi but Valdi had gone back to live with his wife. In his memoir he told the story haltingly, with the kind of understatement one would expect. "After the Liberation my family moved to Paris with me. I had not broken my liaison with Jeanne. I suffered very much in this situation because I was very attached to Hélène, I loved my sons... and we were about to have a baby girl to whom I had given my mother's name of Olga. But I love Jeanne, by whom I also had a daughter, Anne." What Valdi did not mention was that both babies were born in the same month, May of 1946. Maxime Nechtschein said that during the war he seldom saw his father and when he did Valdi was always on the run. He was often obliged to lie for him, something he did not like at all. His father never talked about Jeanne, politics, his work in the Resistance, or anything personal. He was "not much of a talker." However, "he was a very good organizer, very passionate, indefatigable but not practical at all. He had a double life. It was 'la culte du secret.' " G. E. Modigliani in America, 1935 (image credit 14.5) Finally, Valdi moved in with Jeanne. Even then he never talked about her, his son said, and Maxime only met her once or twice. Valdi spent his weekends with Hélène and the children, as if he had been away on some secret mission and returned for a brief holiday. That their father had two other children was something Maxime and his brother did not learn for many years. One of the reasons for Valdi's decision to move in with Jeanne had to do with the state of Anne's health. When she was only sixteen months old she had a cerebral hemorrhage that left her partially paralyzed, with brain damage. Years of therapy and operations would follow before she was able to lead a normal life. All this was happening in 1947, which would have been a terrible year for Jeanne for another reason: her uncle Emanuele had died. After leaving Switzerland at the end of the war, he and Vera returned to Italy in triumph. But his health was fragile and he died there in October 1947, a few days before his seventy-sixth birthday. No doubt Jeanne felt overwhelmed; in any event, this was when Valdi moved in. Ten years later Valdi divorced Hélène and married Jeanne. By then they had a second daughter, Laure, born in 1951. Their father belatedly acknowledged his two illegitimate daughters a year or so before his death in 1993. That would have been in character. Dominique Desanti said, "It is true that the two of them lived only for politics. Militants of that epoch essentially abandoned their children. The best thing was if there was a grandmother on the scene... It was a Bohemian household; they all were. If you wanted to eat, well, you went to a restaurant. Otherwise it was ham and frites or you bought something at a delicatessen. I don't know if Jeanne ever cooked but I'd be astonished if she did. Of course they were very poor. Communist journalists were very poorly paid, considered working class." A rare photograph of Valdi and Jeanne together, postwar, in the countryside with cat (image credit 14.6) Jean-Pierre Haillus agreed. He recalled one time when he was living in Guadeloupe and Valdi arrived there for a conference. They met at the airport. Valdi was in complete sartorial disarray. Everything was unbuttoned and his sole covering above the waist was an undershirt. "A completely Bohemian lifestyle. Jeanne was capable of leaving the house wearing one red shoe and one blue one. It didn't bother her at all. Possessions didn't exist for them. If they had a car it needed repair and wouldn't run. Their apartments were full of old furniture and covered with dust. Books and magazines all over the place." At home they often walked around in the nude, in a curious repetition of Modigliani's fondness for disrobing. Living with Jeanne meant constant theatrical arguments, "very Italian," and family crises played out against a chaotic lifestyle in which parents came and went at unpredictable hours. Jeanne was, as it were, all for her husband, with nothing much left for her children, particularly Laure, in an echo of her mother's attitude. Laure went on to study psychology; her doctoral thesis was the incidence of death among psychotic infants, and also the very rare condition that causes children to mutilate themselves. She is not married and has a daughter, Sarah, now in her twenties. She is unemployed and lives in a working-class quarter of Paris. Haillus believes that Christian Parisot formed a charity and a group of art collectors helps provide for Laure. Her sister Anne, who now lives on a small state pension and is cared for by Haillus, her guardian, does not share in this largesse. One of the reasons why Emanuele fought for Jeanne's legal status had to do with her artistic inheritance. Zborowski and Guillaume had the usual financial arrangement: four-fifths of a work's sale price went to them and one-fifth to the artist or his heirs. Once an artist died it was axiomatic that prices shot up. But when Gerald Reitlinger, author of _The Economics of Taste,_ visited Zborowski's quarters on the rue Joseph Bara in 1922, the Modigliani works were still modestly priced.

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3708, 273, 253, 3072, 4583, 13, 285, 3897, 398, 562, 48085, 20721, 15, 187, 187, 6872, 4342, 20177, 432, 253, 5197, 457, 84, 1783, 273, 941, 432, 253, 31188, 15904, 457, 84, 11604, 30657, 17136, 323, 16609, 281, 4332, 15, 1423, 380, 2173, 941, 5867, 403, 432, 253, 25627, 8404, 285, 19190, 6023, 1338, 5196, 275, 3919, 273, 1016, 807, 15, 496, 436, 1770, 13, 15102, 403, 2546, 281, 2085, 11692, 6021, 941, 323, 253, 16832, 807, 2720, 281, 253, 807, 273, 253, 6630, 15, 1198, 436, 1921, 13, 6021, 941, 275, 436, 1304, 3835, 253, 10333, 281, 4267, 2180, 285, 253, 18825, 941, 3835, 253, 16609, 281, 4332, 2180, 15, 187, 187, 7883, 1680, 10515, 33224, 32, 187, 187, 1552, 2593, 273, 253, 1304, 4648, 941, 327, 11692, 6021, 281, 10957, 7108, 715, 1264, 6021, 246, 4670, 1128, 12973, 13, 4766, 285, 5170, 15, 11279, 432, 271, 5795, 2746, 1128, 8912, 272, 253, 1345, 281, 6266, 3139, 347, 1146, 2406, 13, 4766, 390, 5170, 966, 1128, 609, 5469, 275, 1529, 2593, 273, 253, 1304, 15, 380, 1979, 273, 253, 4766, 13, 1880, 1754, 327, 11692, 38805, 275, 4267, 390, 1754, 327, 1881, 14, 25598, 966, 275, 253, 4050, 6630, 13, 7819, 562, 281, 320, 4829, 8931, 15, 187, 187, 11888, 6021, 347, 253, 17705, 13, 4766, 14, 20666, 18294, 403, 2931, 347, 1110, 342, 247, 1979, 14, 23811, 11692, 6021, 326, 310, 767, 14, 29988, 281, 4021, 253, 4583, 8876, 1979, 14, 23811, 11692, 6021, 15, 3495, 20672, 14, 20666, 18294, 452, 1979, 14, 23811, 38805, 326, 403, 1679, 685, 767, 14, 29988, 273, 253, 8876, 13, 285, 5170, 14, 20666, 18294, 452, 1979, 14, 23811, 38805, 326, 403, 625, 685, 4021, 253, 8876, 15, 187, 187, 510, 13674, 273, 253, 4766, 14, 20666, 30625, 6889, 407, 11692, 1979, 15, 1198, 1264, 14, 10816, 18294, 275, 4267, 13, 253, 4766, 14, 20666, 2491, 310, 670, 370, 1867, 13, 933, 281, 370, 14711, 13, 933, 15, 380, 12714, 273, 247, 11692, 281, 253, 4766, 14, 20666, 30625, 7024, 327, 752, 697, 6021, 310, 5998, 281, 320, 846, 352, 310, 24337, 281, 247, 1264, 14, 10816, 11692, 15, 1348, 329, 11692, 342, 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5886, 281, 253, 4583, 8876, 13, 6889, 689, 673, 15, 496, 4332, 13, 2456, 15, 24, 6, 273, 7747, 313, 1131, 1283, 285, 5662, 10, 6940, 275, 4766, 14, 20666, 18294, 15, 1099, 496, 1180, 13, 326, 37752, 281, 12387, 3041, 7747, 562, 273, 253, 530, 15, 52, 15, 11692, 3072, 273, 28804, 3041, 7747, 15, 1731, 380, 3894, 273, 253, 530, 15, 52, 15, 6782, 3072, 326, 4852, 275, 4766, 14, 20666, 18294, 556, 23028, 689, 673, 15, 496, 16609, 13, 3925, 15, 25, 6, 273, 7747, 6940, 275, 4766, 14, 20666, 18294, 13, 884, 7155, 2792, 625, 685, 275, 4332, 15, 187, 187, 510, 39443, 13, 390, 288, 8165, 562, 13, 273, 253, 4766, 14, 20666, 30625, 556, 644, 11704, 407, 271, 2572, 275, 253, 10764, 273, 253, 6782, 3072, 387, 253, 1029, 285, 1698, 7637, 273, 253, 6021, 3268, 1128, 395, 11467, 4503, 10764, 452, 4395, 598, 390, 1066, 15, 380, 3894, 273, 253, 3072, 275, 253, 5170, 14, 20666, 30625, 556, 28987, 432, 1638, 6, 275, 16609, 281, 1384, 6, 275, 4332, 15, 2058, 253, 1072, 673, 13, 253, 3894, 275, 253, 2406, 14, 20666, 30625, 8899, 432, 2030, 6, 275, 16609, 281, 3285, 6, 275, 4332, 15, 3308, 13, 432, 16609, 281, 4332, 13, 253, 530, 15, 52, 15, 6782, 3072, 556, 2489, 625, 29187, 25865, 1128, 3113, 4942, 625, 275, 253, 1755, 285, 253, 5004, 246, 4670, 13, 285, 11184, 275, 253, 4766, 15, 187, 187, 510, 288, 8165, 273, 253, 4766, 14, 20666, 30625, 556, 644, 247, 11792, 285, 14257, 440, 30933, 264, 1232, 689, 253, 2469, 1740, 8007, 15, 28396, 432, 10333, 13, 1046, 9976, 556, 7402, 342, 247, 4577, 3894, 275, 253, 4766, 14, 20666, 30625, 285, 2169, 10764, 275, 253, 2406, 14, 285, 5170, 14, 20666, 246, 4670, 15, 1621, 2014, 9976, 9572, 562, 347, 1907, 10838, 1025, 253, 4866, 273, 952, 562, 273, 253, 4766, 15, 187, 187, 13641, 3756, 273, 10515, 14, 688, 3188, 2006, 3628, 187, 187, 8457, 253, 5020, 273, 7747, 2965, 715, 253, 4766, 14, 20666, 30625, 13, 253, 5319, 273, 253, 4766, 8800, 247, 2266, 36199, 281, 253, 3072, 4583, 15, 380, 2544, 275, 1110, 5319, 671, 11472, 253, 18825, 2544, 326, 452, 22007, 253, 530, 15, 52, 15, 3072, 1580, 16609, 15, 831, 2593, 37250, 253, 2201, 4342, 28, 253, 7000, 4342, 403, 3559, 275, 17138, 337, 15, 9658, 253, 2234, 7313, 27, 187, 187, 32868, 27, 496, 4332, 13, 760, 884, 6, 273, 4766, 14, 20666, 7747, 574, 417, 12431, 247, 1029, 2143, 11833, 3691, 390, 697, 6425, 285, 4567, 6, 574, 760, 247, 1029, 2143, 11833, 3691, 15, 6295, 10764, 497, 1066, 19836, 432, 16609, 13, 347, 310, 253, 1083, 342, 512, 7747, 15, 2058, 253, 1072, 673, 13, 253, 3894, 273, 4766, 14, 20666, 7747, 342, 690, 6831, 4730, 9461, 432, 1638, 6, 275, 16609, 281, 4567, 6, 275, 4332, 13, 285, 253, 3894, 342, 247, 37589, 457, 84, 4248, 390, 625, 2559, 432, 884, 6, 281, 3436, 7739, 2053, 11701, 275, 11331, 49049, 403, 275, 1386, 342, 253, 9058, 323, 253, 530, 15, 52, 15, 3072, 15, 1630, 187, 187, 19711, 27, 380, 4766, 14, 20666, 1387, 273, 7747, 10652, 8489, 7938, 685, 253, 3072, 432, 16609, 281, 4332, 15, 380, 3894, 273, 4766, 14, 20666, 7747, 7251, 285, 5662, 4829, 25128, 432, 898, 6, 275, 16609, 281, 1668, 6, 275, 4332, 15, 2064, 369, 247, 1199, 17614, 468, 2572, 685, 275, 253, 4583, 3072, 13, 835, 253, 3894, 273, 1110, 11880, 7251, 285, 5662, 9461, 432, 1458, 6, 275, 16609, 281, 1722, 6, 275, 4332, 15, 24646, 13, 253, 3894, 273, 2872, 7747, 13, 11880, 1283, 281, 3285, 13, 275, 253, 4766, 14, 20666, 30625, 6497, 625, 23071, 685, 616, 3894, 275, 253, 3072, 387, 1781, 432, 16609, 281, 4332, 1128, 4064, 1884, 6, 281, 3307, 6, 275, 253, 4766, 14, 20666, 30625, 285, 432, 3349, 6, 281, 3307, 6, 275, 253, 3072, 15, 187, 187, 51, 584, 285, 10570, 79, 5755, 27, 1284, 342, 253, 2120, 6782, 3072, 13, 4766, 14, 20666, 7747, 497, 625, 7393, 1365, 285, 22603, 1037, 11117, 275, 4332, 685, 275, 10226, 15, 1619, 380, 3894, 273, 3032, 4029, 982, 275, 253, 4766, 14, 20666, 3072, 2559, 432, 854, 6, 275, 10226, 281, 2145, 6, 275, 4332, 15, 380, 3894, 273, 19991, 6497, 432, 5096, 6, 275, 10226, 281, 5571, 6, 275, 4332, 347, 253, 3894, 273, 26769, 285, 1284, 2458, 2559, 15, 187, 187, 9709, 5896, 27, 39138, 310, 1679, 1846, 275, 253, 530, 15, 52, 15, 3063, 685, 275, 16609, 13, 285, 436, 310, 11392, 275, 253, 6890, 3894, 273, 4766, 14, 20666, 7747, 665, 403, 7028, 342, 247, 22333, 1246, 15, 9658, 4766, 14, 20666, 7747, 13, 253, 3894, 6497, 432, 10677, 6, 275, 16609, 281, 7288, 6, 275, 4332, 15, 496, 253, 4583, 6782, 3072, 13, 253, 3894, 273, 7028, 952, 342, 247, 22333, 1246, 6497, 432, 10447, 6, 275, 16609, 281, 8073, 6, 275, 4332, 15, 16257, 13, 253, 8394, 273, 4766, 14, 20666, 7747, 665, 452, 1620, 644, 7028, 9461, 432, 1668, 6, 281, 3435, 5294, 13892, 12427, 253, 1818, 275, 253, 2264, 6782, 3072, 15, 187, 187, 56, 12947, 285, 8742, 398, 187, 187, 510, 11792, 5141, 275, 253, 3894, 273, 253, 530, 15, 52, 15, 3072, 326, 310, 275, 253, 4766, 556, 5876, 512, 2201, 18825, 2390, 15, 31565, 273, 4730, 13, 2363, 13, 8645, 13, 7875, 13, 5492, 285, 31908, 13, 253, 3894, 275, 253, 4766, 369, 2057, 3777, 390, 19965, 432, 16609, 281, 4332, 15, 380, 7934, 6517, 281, 436, 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years. The median household income in the U.S. when adjusted for the drop in household size increased from $44,845 in 1970 to $59,127 in 2010. That is an increase of 32%, substantially greater than the increase of 13% prior to an adjustment for household size. The effect of adjusting for household size is most pronounced in the 1970s, a decade in which average household size fell from 3.2 to 2.7. As a result, household incomes in this decade are estimated to have increased by 12.2% instead of a mere 1.9% without adjusting for household size. Household size from 2000 to 2010 was virtually unchanged, inching down from 2.6 to 2.5. Thus, adjusting or not adjusting for household size has virtually no impact on income trends in the “lost decade.” Prior to adjustment, median household income in this decade fell by 7.0%. After the adjustment for household size, the drop in household income is 6.6%. The adjusted median household income in 2010—$59,127—is also no higher than its level 13 years earlier in 1997—$59,194. The “lost decade” acquires one other unique characteristic after incomes are adjusted for household size—it is the only 10-year period since 1970 in which median household income at the end of the period has been less than at the start of the period.20 Middle-Income Demography, 1971-2011 Trends in median household income are a good indicator of overall changes in prosperity, but they leave many questions unanswered: Is the rise in prosperity shared equally? Are those in the middle faring as well as those above or below the middle? Are income gaps increasing or decreasing? Is the size of the middle class expanding or shrinking? Who is in the middle? The analysis of these questions reveals that the share of the American adult population that lives in middle-income households has decreased steadily for the past four decades. This has been accompanied by virtually equal parts movements up and down the income ladder. In other words, there has been both progress and regression in the economic status of American families. However, progress for some demographic groups has been better than for others, and the regression for some groups has been deeper than for others. The winners include seniors (ages 65 and older), married couples and those with a college degree. The losers include young adults, unmarried men, people who have never married and those without a college degree.21 From 1971 to 2011, there was overall progress, with winners outnumbering losers. However, from 2001 to 2011, there was effectively no change in the status of the population overall, and losers outnumbered winners. These findings emerge from the Center’s analysis of data from the Census Bureau’s Current Population Survey for 1971 to 2011.22 The specific data analyzed are from the Annual Social and Economic Supplement conducted in March of each year. In this month, respondents are asked to provide household income data for the calendar year prior to the year of the survey. For this reason, income data in this report cover the 1970 to 2010 period and the demographic data cover the 1971 to 2011 period. Who Is Middle Income? This section of the report uses data on household income to divide Americans into three income tiers—lower, middle and upper. Results from an alternative approach—allowing the public to describe itself as being lower, middle or upper class—are discussed in another section of the report. The size of the middle, whether based on household incomes in 2010 or based on self-described class in the 2012 survey, turns out to be nearly identical. Using income as the criterion, middle-income households are defined as those with a size-adjusted household income that is two-thirds to double the overall median size-adjusted household income. 23 Lower-income households have size-adjusted incomes that are less than two-thirds of the median, and upper-income households have size-adjusted incomes that are more than double the median. The boundaries of the middle-income tier vary by household size. For three-person households in 2010, the middle-income range is about $39,000 to $118,000. The assignment of a household to the middle-income tier depends on what its income is estimated to be after it is scaled to a three-person household.24 A household with reported income less than $39,000 may fall in the middle-income tier if it has fewer than three members. Conversely, a household earning more than $39,000 may fall out of the middle-income tier if it has more than three members. Because the median household income has risen over time, the threshold for entering the middle-income tier has also risen over time. From 1970 to 2000, the low end of the middle-income range increased from about $30,000 to $42,000. The threshold fell to $39,000 in 2010 because of the decline in median household income. The precise income ranges used to classify households into the middle-income tier after adjusting for household size are shown in the accompanying table. How Many Adults Are Middle Income? The size of the middle-income tier varies over time because the incomes of individual households, in relation to the overall median, vary over time. In 2011, 50.7% of adults (ages 18 and older) lived in middle-income households.25 In number, that amounted to 117 million adults out of the U.S. household population of 231 million adults.26 The share of the U.S. adult population that lives in middle-income households has diminished over time. In 1971, 60.8% of adults lived in middle-income households, 10 percentage points more than in 2011. The shrinking, or hollowing out, of the middle-income tier has been accompanied by an increase in the shares of the adult population at the high and low ends of the income distribution—and roughly equal shares have moved up or down. The share of the population in the upper-income tier has risen from 14% in 1971 to 20% in 2011. At the same time, the share in the lower-income tier grew from 25% in 1971 to 29% in 2011. Thus, from 1971 to 2011, the U.S. adult population has become more economically polarized—with relatively more in the top and the bottom tiers, and fewer in the middle. The hollowing of the middle-income tier has been a steady and virtually uninterrupted process over the past four decades. Starting from 1970, every decade has ended with a smaller share in the middle-income tier and higher shares in the lower- and upper-income tiers. No single decade stands out as having energized the movement of people out of the middle. Demography of Middle-Income Adults Because the majority of adults fall into the middle-income tier, the characteristics of the middle bear a strong resemblance to the population overall. The changes in those characteristics also mirror the demographic changes that have swept the U.S. population since 1971. This section summarizes the major findings; the detailed findings are presented in Appendix 1. Among the key observations: Education: In 2011, only 10% of middle-income adults had not earned a high school diploma or its equivalent and 32% had only a high school diploma. Both shares were down notably from 1971, as is the case with all adults. At the same time, the share of middle-income adults with some college education rose from 14% in 1971 to 32% in 2011, and the share with a bachelor’s degree or more increased from 10% to 26%. These improvements in educational attainment are in line with the trend for the U.S. population.27 Age: The middle-income group of adults aged somewhat faster than the population from 1971 to 2011. The share of middle-income adults 65 and older nearly doubled from 9% in 1971 to 16% in 2011. That was a much sharper increase than in the overall population, where the share of those ages 65 and older rose from 15% in 1971 to 17% in 2011. Conversely, the share of young adults, ages 18 to 29, in the middle-income tier fell more sharply than their share in the population at large from 1971 to 2011—from 30% to 22% in the middle-income tier and from 28% to 22% in the population. Race and Ethnicity: As with the full adult population, middle-income adults were more racially and ethnically diverse in 2011 than in 1991.28 The share of Hispanics in the middle-income population increased from 8% in 1991 to 13% in 2011. The share of whites fell from 80% in 1991 to 70% in 2011 as the share of blacks and Asians increased. Marriage: Marriage is less common in the U.S. today than in 1971, and this is reflected in the changing share of middle-income adults who are married with a spouse present. Among middle-income adults, the share fell from 74% in 1971 to 55% in 2011. In the overall adult population, the share of married people with a spouse present fell from 69% in 1971 to 52% in 2011. Meanwhile, the proportion of middle-income adults who have never been married rose from 16% to 27%, mimicking the change in the total adult population. Winners and Losers The steady reduction in the share of the U.S. population that is in the middle has affected all major demographic groups. Regardless of education, age, gender, marriage, race and ethnicity, the share in the middle was either reduced or unchanged from 1971 to 2011. The sole exception to this rule is seniors (65 and older) for whom there was a significant decline in the share in the lower-income tier and a notable rise

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_b_b_prev = tempVec[3].ptr<float>(0) + i; float* ptr_mean_b_g_prev = tempVec[4].ptr<float>(0) + i; float* ptr_mean_b_r_prev = tempVec[5].ptr<float>(0) + i; float* ptr_mean_a_b_next = tempVec[0].ptr<float>(1) + i; float* ptr_mean_a_g_next = tempVec[1].ptr<float>(1) + i; float* ptr_mean_a_r_next = tempVec[2].ptr<float>(1) + i; float* ptr_mean_b_b_next = tempVec[3].ptr<float>(1) + i; float* ptr_mean_b_g_next = tempVec[4].ptr<float>(1) + i; float* ptr_mean_b_r_next = tempVec[5].ptr<float>(1) + i; float* ptr_I = I.ptr<float>(0) + i; float* ptr_q_b = q.ptr<float>(0) + i * 3; float* ptr_q_g = q.ptr<float>(0) + i * 3 + 1; float* ptr_q_r = q.ptr<float>(0) + i * 3 + 2; float sum_mean_a_b = *ptr_mean_a_b_prev * (r + 1); float sum_mean_a_g = *ptr_mean_a_g_prev * (r + 1); float sum_mean_a_r = *ptr_mean_a_r_prev * (r + 1); float sum_mean_b_b = *ptr_mean_b_b_prev * (r + 1); float sum_mean_b_g = *ptr_mean_b_g_prev * (r + 1); float sum_mean_b_r = *ptr_mean_b_r_prev * (r + 1); for (int j = 1; j <= r; j++) { sum_mean_a_b += *ptr_mean_a_b_next; sum_mean_a_g += *ptr_mean_a_g_next; sum_mean_a_r += *ptr_mean_a_r_next; sum_mean_b_b += *ptr_mean_b_b_next; sum_mean_b_g += *ptr_mean_b_g_next; sum_mean_b_r += *ptr_mean_b_r_next; ptr_mean_a_b_next += step; ptr_mean_a_g_next += step; ptr_mean_a_r_next += step; ptr_mean_b_b_next += step; ptr_mean_b_g_next += step; ptr_mean_b_r_next += step; } *ptr_q_b = (sum_mean_a_b * *ptr_I + sum_mean_b_b) * div; *ptr_q_g = (sum_mean_a_g * *ptr_I + sum_mean_b_g) * div; *ptr_q_r = (sum_mean_a_r * *ptr_I + sum_mean_b_r) * div; ptr_I += step; ptr_q_b += step * 3; ptr_q_g += step * 3; ptr_q_r += step * 3; for (int j = 1; j <= r; j++) { sum_mean_a_b += *ptr_mean_a_b_next - *ptr_mean_a_b_prev; sum_mean_a_g += *ptr_mean_a_g_next - *ptr_mean_a_g_prev; sum_mean_a_r += *ptr_mean_a_r_next - *ptr_mean_a_r_prev; sum_mean_b_b += *ptr_mean_b_b_next - *ptr_mean_b_b_prev; sum_mean_b_g += *ptr_mean_b_g_next - *ptr_mean_b_g_prev; sum_mean_b_r += *ptr_mean_b_r_next - *ptr_mean_b_r_prev; ptr_mean_a_b_next += step; ptr_mean_a_g_next += step; ptr_mean_a_r_next += step; ptr_mean_b_b_next += step; ptr_mean_b_g_next += step; ptr_mean_b_r_next += step; *ptr_q_b = (sum_mean_a_b * *ptr_I + sum_mean_b_b) * div; *ptr_q_g = (sum_mean_a_g * *ptr_I + sum_mean_b_g) * div; *ptr_q_r = (sum_mean_a_r * *ptr_I + sum_mean_b_r) * div; ptr_I += step; ptr_q_b += step * 3; ptr_q_g += step * 3; ptr_q_r += step * 3; } for (int j = r + 1; j < img_row - r - 1; j++) { sum_mean_a_b += *ptr_mean_a_b_next - *ptr_mean_a_b_prev; sum_mean_a_g += *ptr_mean_a_g_next - *ptr_mean_a_g_prev; sum_mean_a_r += *ptr_mean_a_r_next - *ptr_mean_a_r_prev; sum_mean_b_b += *ptr_mean_b_b_next - *ptr_mean_b_b_prev; sum_mean_b_g += *ptr_mean_b_g_next - *ptr_mean_b_g_prev; sum_mean_b_r += *ptr_mean_b_r_next - *ptr_mean_b_r_prev; ptr_mean_a_b_prev += step; ptr_mean_a_g_prev += step; ptr_mean_a_r_prev += step; ptr_mean_b_b_prev += step; ptr_mean_b_g_prev += step; ptr_mean_b_r_prev += step; ptr_mean_a_b_next += step; ptr_mean_a_g_next += step; ptr_mean_a_r_next += step; ptr_mean_b_b_next += step; ptr_mean_b_g_next += step; ptr_mean_b_r_next += step; *ptr_q_b = (sum_mean_a_b * *ptr_I + sum_mean_b_b) * div; *ptr_q_g = (sum_mean_a_g * *ptr_I + sum_mean_b_g) * div; *ptr_q_r = (sum_mean_a_r * *ptr_I + sum_mean_b_r) * div; ptr_I += step; ptr_q_b += step * 3; ptr_q_g += step * 3; ptr_q_r += step * 3; } for (int j = img_row - r - 1; j < img_row; j++) { sum_mean_a_b += *ptr_mean_a_b_next - *ptr_mean_a_b_prev; sum_mean_a_g += *ptr_mean_a_g_next - *ptr_mean_a_g_prev; sum_mean_a_r += *ptr_mean_a_r_next - *ptr_mean_a_r_prev; sum_mean_b_b += *ptr_mean_b_b_next - *ptr_mean_b_b_prev; sum_mean_b_g += *ptr_mean_b_g_next - *ptr_mean_b_g_prev; sum_mean_b_

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lines differ from *pol* lines in their mitochondrial genome organization, suggesting that 681A might be a variant of *pol* CMS. On the other hand, restorers for *hau* cytoplasm have not been identified so far and *pol* or *nap* restorers fail to rescue *hau*-induced male sterility ([@b90-64_38]). Another novel CMS gene, *orf288*, co-transcribed with *atp6* was discovered in *hau* CMS ([@b43-64_38]). *Orf288* was cytotoxic to *E. coli* and induced male sterility in *A. thaliana* when expressed from the nuclear genome with or without the mitochondrial targeting presequences ([@b43-64_38]). It was further shown that ORF288 protein was targeted to the mitochondria even when not fused with mitochondrial targeting presequence. These results indicate that *orf288* might be the causal gene of *hau* CMS. Recent studies on *R. sativus* discovered types of CMS other than Ogura CMS. One was found in Korean radish collections and named NWB CMS ([@b70-64_38]); the *Rf* genes for this CMS have not yet been found. Another one was found in a radish of Uzbekistan ([@b44-64_38], [@b55-64_38], [@b56-64_38]). A study of the complete mitochondrial genome sequence of this CMS type, designated as DCGMS, identified the causal gene as a novel chimeric gene, *orf463*, consisting of a 128-bp partial sequences of *coxI* and a 1261-bp sequence of unclear origin ([@b72-64_38]). [@b34-64_38] hybridized two distantly related accessions of *A. thaliana* and obtained male sterile strains whose inheritance pattern in reciprocal crosses suggested CMS. Mitochondrial genome analyses of the two accessions revealed that the causal gene of this CMS was *orf117*. The predicted ORF117 peptide is 56% identical and 69% similar to the ORF108 peptide from *Moricandia arvensis* that induces male sterility in *B. juncea* (see next section). (2) Alloplasmic CMS as a result of interspecific or intergeneric hybridizations ------------------------------------------------------------------------------- Since the establishment of the CMS line of *B. rapa* with the cytoplasm of *Diplotaxis muralis* ([@b38-64_38]), several more male sterile lines have been developed in Brassicaceae ([Table 1](#t1-64_38){ref-type="table"}). In *B. juncea*, the most important oil seed crop in Southern Asia, the cytoplasms of at least eight species induce CMS ([@b3-64_38], [@b53-64_38], [@b54-64_38], [@b64-64_38], [@b73-64_38], [@b77-64_38], [@b79-64_38], [@b82-64_38]). In addition to *D. muralis*, four other cytoplasms induce CMS in *B. rapa* ([@b22-64_38], [@b65-64_38], [@b76-64_38], [@b77-64_38], [@b89-64_38]). Seven *B. napus* CMS lines are known, including the three (Ogura, *pol* and *nap*) mentioned above. The cytoplasm of *D. muralis* induces sterility also in *B. oleracea* ([@b84-64_38]). *Erucastrum canariense* and *M. arvensis* cytoplasms were recently reported to confer CMS in *B. oleracea* ([@b17-64_38]). A CMS line of *R. sativus* with the cytoplasm of *B. maurorum* was produced ([@b2-64_38]). As shown in [Table 1](#t1-64_38){ref-type="table"}, five species, *B. oxyrrhina*, *B. tournefortii*, *D. muralis*, *D. siifolia* and *Enarthrocarpus lyratus*, are effective as donors of male sterile cytoplasm for more than one crop species. The cytoplasm of *D. muralis* induces male sterility in *B. rapa*, *B. oleracea* and *B. napus*, whereas *En. lyratus* cytoplasm confers CMS in *B. rapa*, *B. juncea* and *B. napus*. CMS was also obtained in *B. juncea* as a result of interspecific hybridization between *B. rapa* and *B. juncea*; this CMS was later transferred to leaf mustard (*B. juncea* var. *multiceps*) ([@b101-64_38]), tuber mustard (*B. juncea* var. *tumida*) ([@b107-64_38]) and stem mustard (*B. juncea*) ([@b103-64_38]). Male sterility in *B. juncea* CMS line was found to be associated with a novel gene, *orf220*, which shares 79 homology with *orf222* (*nap*) and 81% with *orf224* (*pol*) of *B. napus* ([@b101-64_38]). Three cytoplasms (*D. berthautii*, *D. catholica* and *D. erucoides*) that confer CMS to *B. juncea* commonly possess *orf108* upstream of *atpA*, and the two genes are co-transcribed. Expression analyses suggested *orf108* as the causal gene in these CMS sources ([@b53-64_38]). *Orf108* was also found in male sterile *B. juncea* obtained by cell fusion between *B. juncea* and *M. arvensis*. The CMS *B. juncea* line derived from the somatic hybridization with *M. arvensis* carried the unaltered mitochondrial genome from *M. arvensis* in which *orf108* is present ([@b78-64_38]). The finding is the first demonstration of a common molecular mechanism underlying CMS in lines of different origin ([@b1-64_38], [@b53-64_38]). Apart from the above species, *orf108* was also found in other wild species including *B. oxyrrhina*, *Sinapis alba*, *En. lyratus* and *D. tenuisilque*, which suggests its wide distribution. However, *orf108* was absent in *D. muralis*, *D. siifolia* and *D. cretasia*. Therefore, it appears that *orf108* is of ancestral origin but is lost or modified in some lineages. Recent finding in *A. thaliana* of CMS-associated *orf117* with 69% homology to *orf108* ([@b34-64_38]) further supports this view. *Orf263* was inferred to be the causal gene in the CMS lines of *B. napus* and *B. juncea* with the cytoplasm of *B. tournefortii* ([@b54-64_38]). In the mitochondria of *D. muralis*, which induces CMS in three *Brassica* species ([Table 1](#t1-64_38){ref-type="table"}), a novel chimeric gene, *orf72*, located downstream of *rps7* and containing a fragment of *atp9*, was identified. Comparison of gene expression and pollen fertility demonstrated the association of the *orf72* with CMS ([@b84-64_38]). (3) CMS plants obtained by cell fusion -------------------------------------- In contrast to sexual hybridization, cell fusion does not require fertilization, and thus a much wider range of hybridization species can be used. Wild species not used in interspecific and intergeneric sexual hybridization have been used for cell fusion to produce male sterile lines ([Table 2](#t2-64_38){ref-type="table"}). In addition to *B. tournefortii*, *D. catholica*, *M. arvensis* and *R. sativus*, which have been used as cytoplasm donors in sexual hybridization, *A. thaliana*, *Orychophragmus violaceus*, *Sinapis arvensis* and *Trachystoma ballii* cytoplasms were transferred into *B. napus*, *B. juncea* or *B. oleracea* by somatic cell fusion to obtain CMS ([@b27-64_38], [@b28-64_38], [@b29-64_38], [@b39-64_38], [@b45-64_38], [@b46-64_38], [@b47-64_38], [@b48-64_38], [@b66-64_38], [@b97-64_38], [@b99-64_38], [@b98-64_38]). Whereas alloplasmic CMS lines obtained by sexual hybridization inherit the mitochondrial genome of the female parent, somatic hybridization can give rise to novel recombined mitochondrial genomes derived from both parental species, which complicates identification of CMS causal genes. Hitherto, two genes have been identified that demonstrate contrasting features in relation to the CMS genes of alloplasmic lines. The progeny of somatic hybrid between *B. juncea* and *

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operations. In the Pentagon and Whitehall, it has become a critical component of a diplomatic and military campaign to blockade, isolate and weaken Iran by hyping its “nuclear threat”: a phrase now used incessantly by Barack Obama and Gordon Brown, and parroted by the BBC and other broadcasters as objective news. And it is fake." Your more recent attempts to convince the public to support yet another military aggression in the Middle East, with the millions of innocent lives that would be lost as a result, are just as sinister. Last week you claimed that Iran had been "caught red-handed...by the forced disclosure". I beg your pardon? You condemn Iran for doing its job, declaring a facility to the IAEA and inviting its inspectors in! And the conclusion you reach is that they've "been caught lying, again"? Incredible from someone supposed to be unbiased. Yesterday you continued in the same vein, writing of "disclosures concerning Iran's alleged attempts to design a nuclear warhead to be mounted on its Shahab long-range missiles that are capable of striking Israel and some European countries." You continue with some conspiracy theory about how the IAEA is hiding this information from the public "for fear of increasing international tensions." Your source for this claim was the NYT,but you didn't pass on their caveat: "its conclusions are tentative and subject to further confirmation of the evidence, which it says came from intelligence agencies...". Why not? This is outrageous, yet again, presenting as fact unsubstantiated claims. Neither was there any mention of El Baradei's recent statement reported by your own newspaper that there is "no credible evidence" that Iran is developing nuclear weapons". 01 October 2009 In his latest column for the New Statesman, John Pilger compares the current drum-beating for war against Iran, based on a fake "nuclear threat", with the manufacture of a sense of false crisis that led to invasion of Iraq and the deaths of 1.3 million people. It's not only Pilger though who's denouncing the British, American and Israeli lies trying to push us all once again into yet another war of aggression. There's also Phillip Giraldi (WMD All Over Again) who shows just how co-ordinated an effort there is really going on in the US, specifically the media - Washington Post - and across the political divide. He also reveals what the ulterior motive for sanctions really is: "sanctions are an extremely blunt instrument. In practice they never work and only solidify support for a rogue regime, witness Cuba. Once sanctions are in place negotiations cease, virtually guaranteeing a slide to war, which is precisely what Howard Berman and The Washington Post would like to see develop." And Washington, London and Tel Aviv... He finishes "Remember the WMD, pilotless drones, chemical weapon labs, and mushroom clouds? The same song is being sung again, but this time everyone should recognize a con job when they see it coming." Then there's Glenn Greenwald (Talking about Iran on the TV) who debated on MSNBC with Washington Post Editorial Page writer Jonathan Capehart ("fresh back from Israel" - where he presumable refined his talking points...well, refined may not accurately describe those comments, but anyway) and Arianna Huffington: It's important to note Greenwald's comments that "the entire time when I was speaking, MSNBC was flashing scary video of Iran testing its missiles (though it omitted video of this and this), interspersed with this melodramatic and frightening caption: It’s genuinely hard to overstate the effect of visuals like this, transmitted over and over and over to a population." Greenwald leads us to Scott Ritter's interview on Democracy Now (Politically Motivated Hype). Scott Ritter was former UN weapons inspector in Iraq from 1991-1998: "Iran is a signatory to the Nuclear Non-Proliferation Treaty. It has a complete inspection regime conducted by the International Atomic Energy Agency. It’s not been found to be in noncompliance. And yet, here we are condemning Iran for doing its job, declaring a facility, inviting inspectors in. And the conclusion it’s reached from this? That they’re producing nuclear weapons. This is politically motivated hype designed to create a situation this coming Thursday that will find the United States unable to reach any sort of agreement with Iran about its nuclear program....if you’re the Iranians and you make a decision that you strategically require an additional source of energy, such as nuclear energy, to supplement your domestic energy usage so that you free up your oil production and gas production for exportation, so you can earn money, this is a big deal. This isn’t insignificant. And so, you’re building this capability. Israel and the United States say they want to bomb it. What do you do? Well, the first thing you do is you build redundancy, and that’s what this new Qom facility represents. It’s redundancy. It’s a backup to the Natanz primary facility. Again, it’s been declared, no nuclear material has been diverted. But it’s there as a backup. The second thing you do is you fire off missiles in a warning that you have an inherent right and capability of self-defense. Israel launched a massive air exercise last year, in which it demonstrated the ability to fly hundreds of aircraft, you know, the distance necessary to strike targets in Iran. The United States is carrying out exercises with Israel as we speak. You know, the bottom line is it’s the United States and Israel which are the more aggressive of the players here. Iran is not an aggressor. Iran has not attacked anybody. Iran is simply trying to do that which it is legally allowed to do: produce enriched uranium for the purposes of nuclear power. It’s Israel, which, by the way, is not a signatory to the Nuclear Non-Proliferation Treaty, claims it will never be a signatory and has a massive nuclear weapons capability—it’s Israel and the United States which are creating a crisis out of nothing. " And finally all this is backed up by outgoing IAEA chief Mohamed ElBaradei ( "no credible evidence" that Iran is developing nuclear weapons). The release of the famous EU report on last years Georgia-South Ossetia conflict which manages to find both sides at fault! Georgia for starting the conflict and wait for it, Russia for 'retaliation' “far beyond the reasonable limits of defense”. Perhaps they ought to have a look at the Afghan and Iraqi conflicts too, or perhaps even the recent Israeli genocide in Gaza...it would make interesting reading if they kept to the same criteria! Shocking seems to be the word of the day considering this next item that Borev flagged: "RAF leaflet box kills Afghan girl". "The box should have broken apart in mid-air but struck the young girl intact." Note the scary comment under the photo 'The RAF tries to reach local people with leaflet drops'. No one can say they didn't reach that little girl, who remains nameless, no British paper has yet published her name and only the Daily Mail has published her age. She was 6 years old. If it had been a British girl we would akready know everything about her and her life. I have checked the BBC, Guardian, Telegraph, Times, Scotsmantwice, Sky News - there's nothing on her name - while the Independent thought it only important enough as a 3 liner at the very end of the ousted US diplomat report above. Disgusting behaviour by the British press. Yet again. Pages About Me "I never meant to say that the Conservatives are generally stupid. I meant to say that stupid people are generally Conservative. I believe that is so obviously and universally admitted a principle that I hardly think any gentleman will deny it. " -- John Stuart Mill "The crimes of the United States have been systematic, constant, vicious, remorseless, but very few people have actually talked about them. You have to hand it to America. It has exercised a quite clinical manipulation of power worldwide while masquerading as a force for universal good. It's a brilliant, even witty, highly successful act of hypnosis." ---- abstract: 'Driving a quantum system periodically in time can profoundly alter its long-time dynamics and trigger topological order. Such schemes are particularly promising for generating non-trivial energy bands and gauge structures in quantum-matter systems. Here, we develop a general formalism that captures the essential features ruling the dynamics: the effective Hamiltonian, but also the effects related to the initial phase of the modulation and the micro-motion. This framework allows for the identification of driving schemes, based on general $N$-step modulations, which lead to configurations relevant for quantum simulation. In particular, we explore methods to generate synthetic spin-orbit couplings and magnetic fields in cold-atom setups.' author: - 'N. Goldman' - 'J. Dalibard' title: | [Periodically-driven quantum systems:\ Effective Hamiltonians and engineered gauge fields]{} --- Introduction ============ Realizing novel states of matter using controllable quantum systems constitutes a common interest, which connects various fields of condensed-matter physics. Two main routes are currently investigated to reach this goal. The first method consists in fabricating materials [@topological; @superconductivity], or artificial materials [@artificial_graphene0; @artificial_graphene; @artificial_graphene2; @photonic1; @photonic2; @photonic3

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Marcela Muñoz Ávila 179 Los siguientes gráfi cos representan la información del cuadro anterior por institución y por años: Gráfi co 3. CDA-Corporación para el Desarrollo Sostenible del Norte y oriente Amazónico Consultas realizadas por año 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 10 12 8 6 4 2 0 Fuente: las autoras. Gráfi co 4. CODECHOCÓ-Corporación Autónoma Regional para el Desarrollo Sostenible del Chocó Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. La participacion en la gestion_final.indd 179 8/18/09 2:28 PM La participación en la gestión ambiental: un reto para el nuevo milenio 180 Gráfi co 5. CORPAMAG-Corporación Autónoma Regional del Magdalena Consultas realizadas por año 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 6. CARDIQUE-Corporación Autónoma Regional del Canal del Dique Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 7. CORPOGUAJIRA-Corporación Autónoma Regional de la Guajira Consultas realizadas por año 1993 1996 1999 2002 2005 2008 0,8 1 0,6 0,4 0,2 0 Fuente: las autoras. La participacion en la gestion_final.indd 180 8/18/09 2:28 PM Gloria Amparo Rodríguez, Lina Marcela Muñoz Ávila 181 Contrastando la información anterior se tiene que las Corporaciones Autónomas Regionales que reportan la realización de consultas con comunidades negras son Cardique, Codechocó, Corpocesar, CVC, Corantioquia y Corpourabá. Las demás aseguran haber realizado sus consultas únicamente con pueblos indígenas. 4.2. Audiencias públicas e intervención de terceros en el otorgamiento de licencias ambientales De la información obtenida sobre audiencias públicas realizadas por el Ministerio de Ambiente, Vivienda y Desarrollo Territorial en el otorgamiento de licencias ambientales se tiene un total de 51 proyectos relacionados por la información ofi cial, divididos en 10 categorías, de la siguiente manera: Cuadro 19. Sector Número de audiencias públicas por sector Hidrocarburos Energéticos Minería Viales Puertos y navegación Plantas de tratamiento y producción Aeroportuarios Relleno Ríos Turísticos Total 11 8 9 7 5 3 3 2 2 1 51 Fuente: las autoras. La participacion en la gestion_final.indd 181 8/18/09 2:28 PM La participación en la gestión ambiental: un reto para el nuevo milenio 182 La anterior información se expresa de forma gráfi ca así: Gráfi co 8. Ministerio de Ambiente, Vivienda y Desarrollo Territorial Audiencias públicas. 1994-2008 Plantas de trat. y prod. Aeroportuario Relleno Rio Tusristicos Hidrocarburos Energéticos Minería Viales Puerto y navegación Cantidad 12 10 8 6 4 2 0 11 8 9 7 5 3 3 2 2 1 Fuente: las autoras. Los anteriores datos señalan nuevamente que los sectores en donde más se presentan audiencias públicas son el de hidrocarburos y el energético, fenómeno que puede ocurrir por el número de solicitudes de licencias ambientales y por la importancia económica y social que representan este tipo de sectores. A continuación se presenta un patrón histórico del número de audiencias públicas que se han realizado por años en el Ministerio de Ambiente, Vivienda y Desarrollo Territorial, según los resultados de la investigación: Gráfi co 9. Ministerio de Ambiente, Vivienda y Desarrollo Territorial. 1994-2008 Consultas realizadas por año 1993 1996 1999 2002 2005 2008 10 12 14 8 6 4 2 0 1 11 3 33 3 3 13 4 4 66 Fuente: las autoras. La participacion en la gestion_final.indd 182 8/18/09 2:28 PM Gloria Amparo Rodríguez, Lina Marcela Muñoz Ávila 183 Desde 1993 hasta el año 2000 se realizaron 36 audiencias públicas ambientales por parte del Ministerio de Ambiente, Vivienda y Desarrollo Territorial, mientras que de 2001 a mediados de 2008 ese número disminuyó a 15, de acuerdo con los datos suministrados por las instituciones, lo que demuestra una disminución importante de la utilización de este mecanismo en los últimos años. En términos porcentuales, el siguiente cuadro expresa, de un total de 51 audiencias públicas, cuántas se realizaron por año: Cuadro 20. A ño Número de audiencias Porcentaje 1994 1 1,9% 1995 13 25,49% 1996 4 7,8% 1997 3 5,8% 1998 6 11,7% 1999 6 11,7% 2000 3 5,8% 2001 3 5,8% 2002 1 1,9% 2003 - 2004 3 5,8% 2005 - 2006 4 7,8% 2007 3 5,8% 2008 1 1,9% Fuente: las autoras. Como se ha planteado en este documento, la autoridad puede convocar a la audiencia pública de ofi cio; sin embargo, en el análisis que hemos efectuado encontramos que son escasas, por no decir casi nulas, las audiencias públicas que se dan de esta forma. Llamamos la atención de las autoridades ambientales para que en casos donde se presentan confl ictos con relación a proyectos, donde la información es escasa, para que de manera oportuna y sin necesidad La participacion en la gestion_final.indd 183 8/18/09 2:28 PM La participación en la gestión ambiental: un reto para el nuevo milenio 184 de requerimientos se convoque la realización de audiencias públicas. De esta forma se puede, además de ofrecer información, minimizar los problemas y aclarar la realización de estos proyectos. En cuanto a las Corporaciones Autónomas Regionales,12 desde 1994 hasta mediados de 2008 se han realizado 164 audiencias públicas. Cinco corporaciones reportan no haber realizado ninguna audiencia en 15 años y las que más reportan se observan en el siguiente cuadro: Cuadro 21. Corporaciones autónomas regionales y de desarrollo sostenible con el mayor número de audiencias públicas realizadas Número de audiencias públicas realizadas por corporación CRC CAR-CUNDINAMARCA CVC CARDIQUE CORANTIOQUIA CORPONARIÑO 58 15 10 9 6 6 Fuente: las autoras. La anterior información se expresa en forma gráfi ca, por institución y por años, así: Gráfi co 10. CRC-Corporación Autónoma Regional del Cauca Consultas realizadas por año 1993 1996 1999 2002 2005 2008 25 20 15 10 5 0 Fuente: las autoras. 12 Análisis sin información de tres Corporaciones Autónomas Regionales. La participacion en la gestion_final.indd 184 8/18/09 2:28 PM Gloria Amparo Rodríguez, Lina Marcela Muñoz Ávila 185 Gráfi co 11. CAR-Corporación Autónoma Regional de Cundinamarca Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 12. CVC-Corporación Autónoma Regional del Valle del Cauca Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. Gráfi co 13. CARDIQUE-Corporación Autónoma Regional del Canal del Dique Consultas realizadas por año 1993 1996 1999 2002 2005 2008 2,5 3 2 1,5 1 0,5 0 Fuente: las autoras. La participacion en la gestion_final.indd 185 8/18/09 2:28

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missing out, the fear of being flamed or forgotten’. Andreas not only regards these fears as justifiable, he traces them back to the rationalism of the Enlightenment and the French Revolution. The Reign of Terror, he thinks, anticipated ‘the terrors of technocracy, which sought to liberate humanness through the efficiency of markets and the rationalism of machines’. The leaps of logic in this passage are not entirely explained by the fact that the guilt-wracked Andreas is, at this late stage of the novel, beginning to lose his mind. Even someone not functioning at full mental capacity could probably come up with at least a couple of reasons why the prospect of running afoul of the Stasi is substantially different to the fear of becoming unpopular or uncool. Yet the categorical confusion appears to belong not simply to Andreas, but to the novel itself. Purity sees the implications of technology in moral and psychological terms. It casts the Internet as a perverter of reality, a symbol of dissolution and death, rather than a new reality to be negotiated. It shows no real interest in the way that information technology or a WikiLeaks-like operation might actually work, or in the fact that the issues raised by the likes of Julian Assange and Edward Snowden are not moral and psychological, but ethical and political. The real potential for the Internet to become ‘totalitarian’ is that makes it possible for governments and corporations to collect vast amounts of personal data at a level of detail unimagined by the Stasi. Purity is not concerned with this question, though it does come down on the side of an orderly public sphere overseen by responsible journalists. Leila, the novel’s most forceful critic of the Sunlight Project, condemns Andreas’s operation for its savage naïveté, like the kid who thinks adults are hypocrites for filtering what comes out of their mouths. Filtering isn’t phoniness – it’s civilization … Andreas Wolf is a man so full of his own dirty secrets that he sees the entire world as dirty secrets. The dissolution of Andreas Wolf would appear to validate this judgement. But in doing so, it also suggests why Purity’s critique of our media-saturated, technology-crazed, apocalypse-haunted historical moment is so thin, why its argument between traditional journalism and new media is a damp squib. Near the end of the book, Andreas becomes so immersed and implicated in the Internet, so enmeshed in its totalitarianism, that his online existence was coming to seem realer than his physical self … The aim of the Internet and its associated technologies was to ‘liberate’ humanity from the tasks – making things, learning things, remembering things – that had previously given meaning to life and thus had constituted life. Now it seemed as if the only task that meant anything was search-engine optimization. The novel seems to want us to treat this kind of lame pronouncement as a serious criticism. What Purity seems unable or unwilling to do, however, is distinguish between a material criticism of the world we live in and the novelistic conceit that casts the Internet as the symbol of a psychologically destructive infinity. Near the end of Freedom, there is a line that might be read as a keynote: The personality susceptible to the dream of limitless freedom is a personality also prone, should the dream ever sour, to misanthropy and rage. One could substitute the word ‘purity’ for ‘limitless freedom’ and the line could slot happily into in Franzen’s new novel, though Purity ups the ante by suggesting that the price of such idealism extends beyond mere misanthropy and rage to neurosis and psychological breakdown. It does so with considerable ingenuity. What it doesn’t do is tell us anything in particular about modern technology. 725 S.E.2d 336 (2012) 314 Ga. App. 628 SECURED REALTY & INVESTMENTS, INC. et al. v. BANK OF NORTH GEORGIA. Bank of North Georgia v. Secured Realty & Investments, Inc. et al. Nos. A11A2020, A11A2021. Court of Appeals of Georgia. March 7, 2012. *338 Charles Merritt Lane, Carrollton, for appellants. Stokes, Lazarus & Carmichael, William Kim Carmichael, Atlanta, Rachel Humphrey, for appellee. McFADDEN, Judge. These appeals arise from a bank's lawsuit to collect amounts due on two promissory notes given or guaranteed by the debtors. The trial court denied summary judgment to the bank as to one of the notes and granted summary judgment to the bank as to the other note. Because there are no genuine issues of material fact, we affirm the grant of summary judgment and reverse the denial. "Summary judgment is proper when there is no genuine issue of material fact and the movant is entitled to judgment as a matter of law. We review the grant of summary judgment de novo, construing the evidence in favor of the nonmovant." (Citations and punctuation omitted.) Brooks v. Gwinnett Community Bank, 311 Ga.App. 806, 717 S.E.2d 647 (2011). So construed, the evidence shows that Secured Realty Investments, Inc. (Secured), executed a promissory note, identified as Note 20, in favor of Bank of North Georgia ("BNG") in the principal sum of $911,557, and Dennis McDowell personally guaranteed the note. Secured also executed another promissory note, identified as Note 21, in favor of BNG in the principal amount of $3.8 million, and McDowell personally guaranteed that note as well. Secured and McDowell defaulted and failed to pay the amounts due to BNG under the terms of the notes and guarantees. BNG sued Secured and McDowell to collect the amounts due. BNG subsequently moved for summary judgment, filing the affidavit of its senior vice-president, along with documentary evidence, which set forth the parties' contracts and accounts, the debtors' defaults and their total debt to BNG. After a hearing, the trial court denied summary judgment to the bank as to Note 20 and granted summary judgment as to Note 21. In Case No. A11A2020, Secured and McDowell appeal from the grant of summary judgment on Note 21; and in Case No. A11A2021, BNG appeals from the denial of summary judgment on Note 20. Case No. A11A2020 1. Secured and McDowell contend that the trial court erred in granting summary judgment in favor of the bank because genuine issues of material fact remain as to their affirmative defenses. The contention is without merit. Under OCGA § 9-11-56, BNG had the burden on its motion for summary judgment to establish that there is no genuine issue of fact and that it is entitled to judgment as a matter of law. Lau's Corp. v. Haskins, 261 Ga. 491, 405 S.E.2d 474 (1991). Where, as here, the record shows that the promissory notes and guarantees were duly executed by the debtors and that they are in default, a prima facie right to judgment as a matter of law was established, and the burden shifted to Secured and McDowell to produce or point to evidence in the record which established an affirmative defense. Helton v. Jasper Banking Co., 311 Ga.App. 363, 363-364, 715 S.E.2d 765 (2011); Reece v. Chestatee State Bank, 260 Ga.App. 136, 138(1), 579 *339 S.E.2d 11 (2003); Miller v. Calhoun/Johnson Co., 230 Ga.App. 648, 649-650(3)(b), 497 S.E.2d 397 (1998). In response to the bank's motion for summary judgment, Secured and McDowell were not entitled to rest on allegations in their pleadings to establish affirmative defenses on which they would have the burden of proof at trial, but were required to come forward with or point to specific facts in the record to establish affirmative defenses. Southeast Reducing Co. v. Wasserman, 229 Ga.App. 1, 4-5(2), 493 S.E.2d 201 (1997). Secured and McDowell failed to point to such specific facts establishing a triable issue as to their affirmative defenses of estoppel and breach of the implied covenant of good faith and fair dealing. (a) "In order for an equitable estoppel to arise, there must generally be some intended deception in the conduct or declarations of the party to be estopped, or such gross negligence as to amount to constructive fraud, by which another has been misled to his injury." (Citation and punctuation omitted.) Griffin v. State Bank of Cochran, 312 Ga.App. 87, 94(2)(a), 718 S.E.2d 35 (2011). Similarly, under the doctrine of promissory estoppel, "[a] promise which the promisor should reasonably expect to induce action or forbearance on the part of the promisee or a third person and which does induce such action or forbearance is binding if injustice can be avoided only by enforcement of the promise." (Citation and punctuation omitted.) Georgia Investments Intl. v. Branch Banking & Trust Co., 305 Ga.App. 673, 675(1), 700 S.E.2d 662 (2010). However, promissory estoppel does not apply to vague or indefinite promises, or promises of uncertain duration. Id. In this case, Sec

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such as hotels, restaurants, and entertainment venues. Studies have shown that the migrant population tends to have lower educational attainment, lower income, and lower access to health services compared to permanent residents who hold a *hukou*. Most migrants are sexually active and are vulnerable to HIV and other STIs. A study in Guangdong found that the HIV awareness rate among the migrant population was only 49%, that 8% of the participants had extramarital sex in the last year and that only 72% of them used condoms in their most recent extramarital sexual contact (Liu et al. [@CR18]). A study in Foshan city showed that HIV awareness and risk behavior varied for different occupations among the migrant population. HIV awareness was particularly low among workers in the entertainment, restaurant, and construction industries. The study also showed that 31% had engaged in commercial sex and 9% reported non-commercial casual sex in the last year (Chen et al. [@CR4]). A similar study conducted in Shenzhen found that 4% of surveyed migrants had taken part in commercial sex and only 36% of them reported consistent condom use (Sun et al. [@CR25]). An exaggerated vulnerability is experienced by individuals in dual-risk populations, such as migrants who are MSM. In a study of migration patterns among MSM, Guangdong had the highest migrant inflow ratios---migrant MSM were moving into Guangdong from areas of higher HIV prevalence among the broader MSM population (Mi et al. [@CR19]). A study conducted in Guangzhou showed that migrant MSM, compared to local MSM, have higher odds of reporting unprotected anal intercourse, having multiple male sexual partners, and lower rates of condom use (Wu et al. [@CR31]). ### Surveillance Among Migrant Workers {#Sec33} Because migrants were significantly over-represented among HIV case reports, six sentinel surveillance sites were set up in the Pearl River Delta region, where the migrant population is most concentrated, beginning in 2010. The annual HIV prevalence among migrants sampled at the six sites overall was 0.04%, 0.14%, 0.12%, 0.08%, 0.17%, 0.04%, 0.04%, and 0.17% in the years from 2010 to 2017, respectively. A cross-sectional study in Zhuhai found that 75% of PLWH were migrants (Li et al. [@CR15]). A similar study in Dongguan found that the proportion of migrants among PLWH rose from 52% in 2010 to 71% in 2015 (Li et al. [@CR14]). A study conducted in Zhongshan in 2010 estimated an HIV prevalence of 0.13% among the migrant population (Tan et al. [@CR27]). A cross-sectional study conducted in three medium-sized Guangdong cities with large floating populations found the prevalence of HIV and syphilis were 0.17% and 1.31%, respectively (Fu et al. [@CR7]). Conclusion {#Sec34} ========== With sudden and rapid trade liberalization and economic development as a backdrop, China's HIV epidemic has taken a somewhat unique course in Guangdong province. Although slow to get started, with only 500 cases identified cumulatively as of 2003, HIV prevalence increased rapidly, particularly among high-risk groups. Guangdong must redouble its efforts in prevention and expand testing, treatment, and care if it is to bring its HIV epidemic under control. Authors gratefully acknowledge Jennifer M. McGoogan, who provided input and assisted with editing. Tag Archives: lunar This Friday night and Saturday morning is the best time to see the best lunar eclipse ever!! Okay, slight exaggeration but this lunar eclipse is definitely the longest for 100 years! And it is visible almost everywhere in the world… except for Northern America. Considering they had the solar eclipse last year, I think they will survive. What is a Lunar Eclipse? As covered in a similar post earlier this year, a lunar eclipse occurs when the Moon passes behind the Earth and into its shadow. The Moon does not have its own light source; that big pizza pie in the sky is reflecting light from the Sun on to the Earth. So when the Sun, Earth, and Moon are all aligned, it means the Moon will pass into the shadow of the Earth. This also means a lunar eclipse only happens during a full moon. Waxing and Waning Moons occur due to the odd-angle the Moon sits relative to the Earth and the Sun. The great news is you don’t need any special equipment; no funky glasses or special telescopes. Just pull up a seat and gaze at the moon. Bring snacks as well because lunar eclipses can last a while, and this one is the longest. Experts (like NASA and the Sydney Observatory) advise the moon will be eclipsed for one hour and 43 minutes!! During this time, we have the greatest opportunity to witness a “Blood Moon”. Wait… What is a Blood Moon? Some cultures used to refer to a total lunar eclipse as a blood moon. When the direct sunlight is completely blocked, the only other light seen is refracted through Earth’s shadow. This light looks red because of the ‘Rayleigh scattering‘ – that’s the scattering of light by particles. Light, as we see it, is a spectrum of colours. When it is refracted (or split) through the atmosphere, we can see different colours. This is most noticeable with the blue sky and the different colours in sunsets due to dust particles in the air. For a lunar eclipse, the Sun’s light refracts around the edge of the Earth and hits the Moon. Blue and violet wavelengths scatter more than red and orange wavelengths, so the red is more like to reach the moon. Thus, it looks like the Moon is bleeding. When and Where Can I See the Blood Moon? The absolute best viewing points are from Western Asia, across the Middle East, and East Africa. If you are in Australia, Oceania, Europe, and the rest of Africa, you still have a good chance of a great site. North America and Greenland are out of luck this year. Australia Not the best timing for us but an early start shouldn’t kill me. If you are specifically after the Red, then make sure you are comfortable looking up around 4.30am AEST on Saturday morning. The total eclipse should occur between 5.30am and 6.30am, with the Moon setting around 6.55am. The Moon is going to be close to the horizon, so look to the West-South-West. Asia Those in Central Asia will probably have the best viewing of all. Look up from around 3.30pm and you might be able to catch the Mars Opposition at the same time. For those in India, you should aim for around 11:50pm local time on Friday night. Middle East The Middle East should be able to see the whole event in its entirety. That’s 103 minutes to make yourself comfortable. The eclipse should start around 10:24pm local time. Europe The days are pretty long in Europe right now. Follow your early dinner with an evening walk to the best vantage point by 8.45pm. With your warm Summer nights, you can probably stretch out on the grass and soak it all in. I’m a little jealous. Africa Eastern Africa will have the best viewing across the continent with other regions maybe missing the start. My contacts tell me the eclipse should be completely visible in Eastern Africa from 3.30pm to 5.15pm local time. South America Most of South America will only catch the tail-end of the eclipse, after sunset on Friday 27 July. However, don’t be too disappointed because your next big event is a total solar eclipse on 2 July 2019, with totality running through Chile and Argentina. Still, tonight’s event is a nice way to kick off the evening. Yes, I will most likely be dragging my tired sorry butt out of bed early in the morning to check it out. Due to my sleep deprivation during the last three weeks, I am giving no guarantees for photos. You’ll just have to wait and see.--- title: "R Notebook" output: html_notebook --- This is an [R Markdown](http://rmarkdown.rstudio.com) Notebook. When you execute code within the notebook, the results appear beneath the code. Try executing this chunk by clicking the *Run* button within the chunk or by placing your cursor inside it and pressing *Ctrl+Shift+Enter*. ```{r} plot(cars) ``` Add a new chunk by clicking the *Insert Chunk* button on the toolbar or by pressing *Ctrl+Alt+I*. When you save the notebook, an HTML file containing the code and output will be saved alongside it (click the *Preview* button or press *Ctrl+Shift+K* to preview the HTML file). The preview shows you a rendered HTML copy of the contents of the editor. Consequently, unlike *Knit*, *Preview* does not run any R code chunks. Instead, the output of the chunk when it was last run in the editor is displayed. Zeus, after having been the leader of the victory of the Olympic gods against the titans, became the supreme god and, sitting on his throne, he started to reign over the world when the God raised his arm unveiling his powerful lightning bolts. The other gods bowed down in a sign of respect. No, God had as much authority as Zeus. Only the goddess Hera, the wife of Zeus, was as esteemed as

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’t stand up to research. A study of New York City schools found a positive relationship between principal experience and school performance, which was broadly defined to include not just test scores, but other measures such as student absences. Researchers suggested an important takeaway from their findings should be that “policies that lengthen principals’ careers will, on average, improve school performance.” Leading a school is a tremendously challenging job which requires a complex set of skills. Many of those skills cannot be taught in graduate school but must be mastered through years of trial and error. Experienced principals are better positioned to cultivate relationships that will lead to success, support teachers instructionally, and train the next generation of school administrators in how to lead effectively. Their compensation should recognize and reward the value that they bring to the job. One of the most troublesome outcomes of North Carolina’s principal pay plan is that it discourages principals from working in schools that need strong leadership the most. Research is clear that having an effective principal in place is especially crucial in schools that serve our most disadvantaged students. Our policies must encourage principals to want to work in those schools, or at the very least not deter them from doing so. Unfortunately, the new plan does just that. North Carolina’s principal pay rate is based on the last three years of growth data. If a principal who has been rated “exceeded growth” for three consecutive years moves into a low-performing school, he or she has two years to bring that school up to the “exceeded” level before seeing a reduction in salary. In schools that generally employ the least experienced teachers and have the highest rates of teacher turnover, that’s a very difficult proposition. When the new pay plan was implemented, some North Carolina principals faced reductions in salary of more than $20,000. The legislature’s response to concerns about this fact was to institute a “hold harmless” clause whereby principals who didn’t see enough standardized test growth would see their salaries frozen at the level of the previous year. The clause was renewed for the upcoming school year, but again frozen at 2016-17 levels, meaning principals whose students didn’t show enough growth will see a second straight year with no raise. That’s not an effective approach when it comes to attracting and retaining school leaders. Principals are second only to teachers among school-related factors in terms of impact on student learning. It’s essential that we treat them in ways that will lengthen their careers and encourage the best among them to work in schools where their talents are needed most. The General Assembly’s current approach to compensation does a grave disservice to our veteran principals and will further weaken North Carolina’s low-performing schools. It’s a model in need of a major overhaul. Justin Parmenter was named a finalist for Charlotte-Mecklenburg Schools teacher of the year in 2016. He currently serves as a Design Team member with Hope Street Group’s North Carolina Teacher Voice Network and sits on the Advisory Board of Red 4 Ed NC. He writes frequently about public education in North Carolina at http://notesfromthechalkboard.com/ where this article originally appeared.Q: User-Entered value for Array Size doesn't actually change the array's size. [Java] So as the title says, I'm trying to get a user inputted size to my array, yet every time I run the program it does not change the array size. I'm pretty sure its something to do with my constructors but i'm not positive. Any help would be appreciated! Class 1 (Numbers) package lab1; import java.util.Random; public class Numbers { public int size; public Integer[]arr = new Integer [size]; public Numbers () { for (int i = 0; i < size; i++){ arr[i] = new Integer(i); } } public Numbers(int size){ this.size = size; for (int i = 0; i < size; i++){ arr[i] = new Integer(i); } } public void generateNumbers(){ System.out.println(arr.length); Random rand = new Random(); for (int i = 0; i < arr.length; i++) { arr[i] = rand.nextInt(100); } } public int count(int val){ int count = 0; for (int i = 0; i < arr.length; i++){ if (arr[i] == val){ count++; } } return count; } public String toString() { StringBuilder builder = new StringBuilder(); for (int i = 0; i < arr.length; i++){ builder.append(arr[i]).append(" "); } return builder.toString(); } } Class 2 (Lab1) package lab1; import java.util.Scanner; public class Lab1 { public static void main(String[] args) { Numbers numbers = new Numbers(); @SuppressWarnings("resource") Scanner input = new Scanner(System.in); int menu = 1; while (menu != 0){ System.out.println("1 to create array of new size\n" + "2 to generate random numbers into array\n" + "3 to count a value\n" + "4 to display array\n" + "0 to quit\n"); menu = input.nextInt(); switch (menu) { case 1: System.out.println("Enter new size:\n"); int size = input.nextInt(); size = numbers.size; System.out.println("Array has been generated of size: " + numbers.size + "\n"); break; case 2: numbers.generateNumbers(); System.out.println("Numbers have been generated\n"); break; case 3: System.out.println("Enter number to search for:\n"); int num = input.nextInt(); System.out.println("There are " + numbers.count(num) + " of the number " + num); break; case 4: System.out.println(numbers.toString()); break; } } } } A: First problem: you're not changing the value of size in your instance of Numbers: size = numbers.size; This updates the local variable size, not the member variable of numbers, overwriting the value you just read from the scanner. To update the member variable with that value: numbers.size = size; Second problem: you're not actually changing the size of the array. The array is created when the instance of the class is initialized: public int size; public Integer[]arr = new Integer [size]; At the time it is created, size is zero, so arr is initialized to be a zero-length array. Changing the value of size won't change the size of arr automatically. You will need to create a new instance and assign it to the arr member variable. If you are specifying this at construction time: public Numbers(int size){ this.size = size; this.arr = new Integer[size]; for (int i = 0; i < size; i++){ arr[i] = new Integer(i); } } Note that because size == 0 initially, your default constructor (public Numbers()) does nothing: the body of the for loop for (int i = 0; i < size; i++){ is never executed, because i == 0 and size == 0 initially, so 0 < 0 is false. You should probably just remove the default constructor, so you always have to specify a value for size to construct the instance. If you remove the default constructor, you can remove the inline initialization of arr: public Integer[]arr; since a non-null value will be assigned in the constructor. Alternatively, if you only ever use Numbers in the code you've given, you can get rid of both constructors, and just declare your fields as: public int size = 0; public Integer[] arr = new Integer[0]; However, in your code, you are trying to change the length of the array after it has been constructed. In this case, you would need to create a new array whenever you change the value of size, for example: numbers.size = size; numbers.arr = Arrays.copyOf(numbers.arr, numbers.size); Arrays.copyOf will appropriately truncate your array or pad it with zeros, depending upon whether size is less than or greater than the current length of the array. Note that it would be usual to encapsulate such changes in a method on Numbers: public void setSize(int size) { this.size = size; this.arr = Arrays.copyOf(this.arr, size); } and make the fields private, so that they can only be updated by methods in Numbers: private int size; private Integer[]arr; Finally,

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why each factor is insufficient, (c) then makes a blanket assertion that the district court abused its discretion because these factors combined with his employ- ment record, lack of criminal record for 70 years, and community ties, were not present to an exceptional degree to warrant departure. The majority’s analysis blatantly disregards the mandate of Koon and the amended Sentencing Guidelines. The United States Supreme Court in Koon ruled that "Congress allows district courts to depart from the applicable Guideline range if ‘the court finds that there exists an aggravating or mitigating circum- stance of a kind, or to a degree, not adequately taken into consider- ation by the Sentencing Commission.’" See Koon, 518 U.S. at 92 (citing 18 U.S.C. § 3553(b)). Several factors mentioned by the Sen- tencing Guidelines may combine to create mitigating or aggravating circumstances sufficient to warrant a basis for departure. See gener- ally Debeir, 186 F.3d at 573. Consistent with Koon, the district court properly found the combination of permissible factors placed the case outside of the heartland of cases contemplated by the Sentencing Guidelines. The district court examined a variety of factors and found Coble to be a 75-year-old man who had no criminal record, served as a combat pilot in two wars, employed as a commercial airline captain, had strong family ties, and whose sole offense was to attempt to use a bogus comptroller’s warrant to satisfy a tax lien against his prop- erty. The district judge stated that in his 17 years of sentencing, he did not think that there has been a federal court who sentenced anyone with Coble’s characteristics within the initial guideline range. (J.A. at 237.) In his institutional experience, Coble’s case was outside of the UNITED STATES v. COBLE 17 heartland of cases contemplated by the guidelines and some departure was warranted. The district judge’s considerable sentencing experi- ence and familiarity with other tax cases are crucial to understanding why the judge departed in this case. At sentencing, the district judge exercised considerable restraint and integrity in announcing his ruling. He acknowledged that he could exercise his discretion and grant an undeserved "acceptance of responsibility" three level departure from the applicable offense level and such a ruling would be almost "appeal proof." (J.A. at 237.) Instead, he considered his experience with tax cases and stated that, in 17 years, he had not seen anyone sentenced to a lengthy term of incarceration for this offense where the defendant had Coble’s unique personal characteristics. The district judge’s decision to depart two levels, a frugal two levels, embodied the traditional permissible exercise of discretion in sentencing. See Koon, 518 U.S. at 98. District courts have an institu- tional advantage and vantage point over appellate courts in comparing factors because district courts see so many more Sentencing Guide- line cases than do appellate courts. See Koon, 518 U.S. at 98 (acknowledging that in 1994 approximately 94% of Guidelines cases were not appealed); United States v. Hairston, 96 F.3d 102, 106 (4th Cir. 1996) (acknowledging the institutional advantage of district court in determining sentences). The district judge’s findings of fact con- cerning specific circumstances of a case are important because it per- mits the flexibility necessary for a defendant to be appropriately sentenced when his case involves unique and unusual facts. See Koon, 518 U.S. at 99. See, e.g., United States v. Reilly, 178 F.3d 1288 (4th Cir. 1999) (unpublished) (upholding district court’s eleven level departure on the grounds of post-offense rehabilitation after the dis- trict court made extensive factual findings). The majority sweeps aside Judge Bullock’s 17 years of institutional wisdom and casts a fleeting glance at Koon’s acknowledgment that Congress allows a dis- trict court to depart from the applicable Guideline range if the district court finds atypical mitigating circumstance not adequately taken into consideration by the Sentencing Commission. See Koon, 518 U.S. at 91. In sum, the majority makes a de novo determination that if it were in the district court’s position, it would have decided the case differ- ently. Under Koon, an appellate court should reverse a district court’s 18 UNITED STATES v. COBLE decision if the district court abuses its discretion, not if it disagrees with the district court’s decision. See, e.g., United States v. Goodman, 2001 WL 273143, *2-3 (4th Cir. 2001) (unpublished) (applying the standard in Koon and holding that, even though it was a very close case, the court cannot conclude that the district court abused its dis- cretion in departing downward). The majority’s decision comes with- out the benefit of the trial judge’s sentencing experience or impression of the testimony presented at Coble’s trial.3 The majority’s position is completely at odds with the mandate of Koon to review a downward departure from the Sentencing Guidelines for an abuse of discretion. The district court did not abuse its discretion in finding Coble’s case was atypical. The Sentencing Guidelines structure sentencing in a way that adds predictability to the sentencing process. In drafting these guidelines, the Sentencing Commission could not possibly con- template every type of circumstance conceivable in sentencing. There is still room for individualized consideration of the whole person within the framework of the Sentencing Guidelines. Coble is a recal- citrant tax evader, a 75-year-old man, who had no criminal record, served as a combat pilot in two wars, has strong family ties, and had a good employment record as a commercial airline captain. Coble was convicted because he attempted to use a bogus comptroller’s warrant to satisfy a tax lien. The population of offenders possessing Coble’s offense and other characteristics is small, and indeed, rare. The dis- trict judge could find no case which factually compared to Coble’s case in his 17 years experience, and decided to impose a frugal two level downward departure from the applicable Sentencing Guidelines which allowed him to place Coble in home electronic detention for six months and on probation for three years. I respectfully dissent because the district court did not abuse its discretion in this case and I would affirm the district court’s judgment. 3 This appeal follows a contested trial and sentencing hearing where the Government did not succeed at an attempt to link Coble to a group which is notorious for promoting tax evasion schemes. The Government could not prove that Coble was a member of the group or an adherent to the group’s wide ranging criminal activities. MANUFACTURED IN OUDENNARDE (FLANDERS) SILK AND WOOL WITH GOLD THREADS ADDED TO THE SURFACE MIDDLE OF THE 16TH CENTURY The two Flemish tapestries of the Bagatti Valsecchi Museum called Mercury and his Children and The Sun and his Children, might be the extant portion...Class Win and P2 Overall at Bathurst 12H Patrick Long, Marc Lieb, David Calvert-Jones and Matt Campbell scored a sensational class win and claimed p2 overall in a hectic, unforgettable Liqui-Moly Bathurst 12 Hours on Saturday, at the legendary Mount Panorama circuit. The #12A Ice Break Coffee Porsche 911 GT3 R, run by Competition Motorsports, ran a strong weekend throughout, progressing through the unique qualifying format to ultimately take place in the Top Ten shootout, where new Porsche Junior Matt Campbell qualified 9th overall. During the race, which saw a characteristic high number of safety car periods due to Mount Panorama’s incredibly narrow confines and large, varied grid, the Ice Break team led for a few stretches but was in and amongst the fight at the front all day. The team did incur three penalties in the race for various infractions, but were running first in class and P3 overall when pre-race favorite Shane Van Gisbergen spectacularly crashed out from P2 with just minutes remaining. 2016 FIA WEC Champion Marc Lieb said, “Second place and class victory feels pretty good. We had to cope with a lot of minor setbacks, probably more than any other team, and that alone makes this a super result.” Patrick remarked, “My stints were good. During the second stint I unfortunately nudged a Mercedes. I wanted to overtake it to snatch the lead but he didn’t budge an inch and I didn’t want to risk anything. So I decided to pull back and keep my position. But I was on the dirty side of the track and I couldn’t avoid touching the car. Luckily nothing more happened.”North Korea’s dependency on China for energy and food has long been cited as a source of Chinese political leverage and a primary factor that could influence North Korean stability. But if North Korea depends on China for the bulk of its food and fuel, why does China not punish tiny North Korea for biting the hands that feed it? On the contrary, underlying trends run in the

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that an "altercation might arise." Mrs. Dickey directed the Balko's daughter "not to be upset and to avoid any confrontation with the Anthonys," and indicated that she "would attempt to reach the police." The police were called and the judge talked to them. Mrs. Dickey then asked the judge to advise her of the proper course to take in the event the Anthonys removed the children before the police arrived to inform them of the custody order. The judge responded that she should charge the parents with abduction in the Magistrate's Court. Later, that afternoon, Mrs. Dickey discovered that Mr. and Mrs. Anthony had in fact retrieved two of their three children. She thereupon signed a complaint against the Anthonys for child abduction. In pertinent part, that complaint recites that Mr. and Mrs. Anthony "did . . . unlawfully COMMIT THE ACT OF CHILD ABDUCTION to-wit: did then and there remove Dolores Anthony, age two years, and Maria Anthony, age four years, from legally appointed guardians without permission of court." On the basis of this complaint, an arrest warrant was issued by a Justice of the Peace. The Anthonys' complaint alleges, and Mrs. Dickey does not dispute, that pursuant to this warrant Mrs. Anthony was arrested by a Delaware state trooper, detained for four hours for interrogation and other police procedures and released after posting a $500 bail bond. *571 Mr. Anthony, according to the complaint, surrendered to the police voluntarily and, after undergoing interrogation and other procedures, was released on his own recognizance. At the request of the Division of Social Services, the charges against the Anthonys were subsequently dismissed pursuant to an order issued by the Family Court. In her affidavit, Mrs. Dickey states that her sole purpose in charging the Anthonys with abduction was "to seek return of the children before their expressed threat to leave the state had been carried out." She further states that it was never her intention "to punish, harass or persecute the Anthonys" and that she acted "with the sole intention of providing the Anthony children with the protection I felt they needed." The Anthonys were arrested for allegedly violating Section 624 of Title 11 of the Delaware Code, which provides as follows: Whoever, without the color of right, forcibly abducts, takes or conveys away any child under the age of 12 years, from the home or usual place of abode of such child, or from the custody and control of the parent or lawful guardian of such child; or Whoever, without the color of right, and against the consent of the parent or lawful guardian of such child, persuades or entices from the usual place of abode or house of such child, or from the custody and control of the parent or guardian of such child; or Whoever knowingly secretes or harbors such child, with the intent to deprive such parent or guardian, or any person who may be in lawful possession of such child, of the custody, care and control of such child Shall be fined not more than $500, or imprisoned not more than 10 years, or both. The Anthonys observe that the respective subsections of this statute require that the alleged abductors act either "without the color of right" or "knowingly." From this language they infer that a necessary element of the crime defined by Section 624 is knowledge on the part of the alleged abductors that they lack lawful custody over the children that they are accused of abducting. Mrs. Dickey, they claim, was fully aware that the Anthonys had not been apprised of the Family Court's custody order when they retrieved their children from the Balko household. Hence, they conclude, Mrs. Dickey lacked probable cause to suspect the Anthonys of child abduction when she secured the warrant for their arrest. Additionally, they maintain that Mrs. Dickey's conceded purpose of "seek(ing) the return of the children before their threat to leave the state had been carried out," while perhaps well-intentioned, was nevertheless an improper motive for securing an arrest warrant. Consideration of the Anthonys' argument must begin with the observation that Mrs. Dickey neither arrested the Anthonys herself nor made the formal determination that there was an adequate legal foundation for that arrest. Mrs. Anthony was arrested by a Delaware state trooper, while Mr. Anthony surrendered to the police voluntarily. The determination that probable cause existed to arrest the Anthonys was made by the magistrate who signed the warrant for their arrest. Mrs. Dickey's participation in these events was limited to appearing before that magistrate and averring facts concededly true and purportedly indicative of the Anthonys' criminal conduct.[3] Thus, she essentially acted as a complainant, whose affidavit to a judicial officer serves to trigger criminal proceedings. At common law, a complainant who initiates unfounded criminal proceedings is potentially liable only for the tort of malicious prosecution. Distinguishing actions for false arrest and imprisonment from actions for malicious *572 prosecution, Professor Prosser has written that: The distinction between the two lies in the existence of valid legal authority for the restraint imposed. If the defendant complies with the formal requirements of the law, as by swearing out a valid warrant, so that the arrest of the plaintiff is legally authorized, the court and its officers are not his agents to make the arrest, and their acts are those of the law and the state, and not to be imputed to him. He is, therefore, liable, if at all, only for a misuse of legal process to effect a valid arrest for an improper purpose. The action must be for malicious prosecution. Prosser, Law of Torts, p. 62. Since she complied with the proper legal formalities and played no role in the actual arrest and detention of the Anthonys, Mrs. Dickey's liability at common law, if any, must rest on a theory of malicious prosecution. The law of malicious prosecution likewise provides the controlling legal framework for determining her liability under Section 1983 as well. Conduct which gives rise to a cause of action for malicious prosecution may also constitute a violation of Section 1983 if that conduct is undertaken under color of state law and results in a deprivation of a federally secured right. See Nesmith v. Alford, 318 F.2d 110, 126 (5th Cir. 1963). In passing upon a claim brought under Section 1983, however, the Third Circuit has cautioned that "the § 1983 right of action should not be construed to be in derogation of the common law." Johnson v. Alldredge, 488 F.2d 820 (1973). Relying on this principle, that court has held, for example, that "officials immune from damage suits at common law would also be immune from such suits under Section 1983." Id. And, aside from the immunity from suit available to state officers acting within the scope of their official discretion, other defenses, likewise derived from the common law, are also available in Section 1983 suits. In Pierson v. Ray, 386 U.S. 547, 87 S.Ct. 1213, 18 L.Ed.2d 288 (1966), the Supreme Court reiterated that Section 1983 "should be read against the background of tort liability" and accordingly permitted police officers, sued under Section 1983 for committing an unconstitutional arrest, to invoke the defense of "good faith and probable cause" traditionally claimed by police officers in a common law action for false arrest. The Supreme Court's reliance on the common law in Pierson, as well as the similar approach of this circuit in Johnson, suggests that wherever common law tort doctrine would afford protection from liability, similar protection must be available in analogous actions brought under Section 1983. We turn, therefore, to the law of malicious prosecution to determine not only Mrs. Dickey's liability under state tort law but her liability under Section 1983 as well. Traditionally, liability for malicious prosecution will not be imposed if the defendant initiated criminal proceedings either with probable cause to believe that the plaintiff was guilty or for the primary purpose of bringing an offender to justice.[4] Prosser, *573 Law of Torts, § 113, p. 853; Restatement of the Law of Torts, § 653, p. 382; Nesmith v. Alford, 318 F.2d 110, 121 (5th Cir. 1963). Because either probable cause or a legitimate law enforcement objective will suffice to defeat an action for malicious prosecution, the standard for recovery in such actions is more stringent than in the kindred area of false arrest, where the defendant police officer must show both good faith and probable cause in order to prevail. See Pierson v. Ray, supra; Bivens v. Six Unknown Agents, 456 F.2d 1339, 1347-1348 (2nd Cir. 1972). As Professor Prosser has observed, a more rigorous standard of liability is appropriate in an action for malicious prosecution because the defendant "has proceeded under the proper legal formalities." Prosser, supra, p. 853. A complainant who swears out an arrest warrant before a magistrate entrusts that magistrate with the task of evaluating the legal sufficiency of the charges he has brought; assuming his motive is proper, the complainant should not be penalized for subsequently disclosed errors in legal judgment. Similarly, even if the complainant has acted in bad faith, the goal of "efficient enforcement of the criminal laws" requires that he be free from liability when he has commenced criminal proceedings in a reasonable and justifiable belief that the alleged wrongdoer is guilty. See Restatement, Law of Torts, Introductory Note, p. 380. In the present case, it is unnecessary to examine Mrs. Dickey's motivation

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, and all that. She can see him stumbling to the house with his head down, breathing hard through his nose. Viva ze bool. "By then I knew I was in bed, but I could hear this low voice that didn't sound like mine at all, it sounded like some stranger's voice, and it couldn't put corners on any of the words it was saying. 'Ell-ee-itch-un, ell-ee itch-un,' that's what it sounded like. 'Ell-ee itch-un, Ish!'" Tell me which one. Tell me which one, Trish. Harvey falls silent, thinking. Considering. The dust motes dance around his face. The sun makes his T-shirt almost too dazzling to look at; it is a T-shirt from a laundry-detergent ad. "I lay there waiting for you to run in and see what was wrong," he finally says. "I lay there all over goosebumps, and trembling, telling myself it was just a dream, the way you do, of course, but also thinking how real it was. How marvelous, in a horrible way." He stops again, thinking how to say what comes next, unaware that his wife is no longer listening to him. Jax-that-was is now employing all her mind, all her considerable powers of thought, to make herself believe that what she is seeing is not blood but just the Volvo's undercoating where the paint has been scraped away. Undercoating is a word her subconscious has been more than eager to cast up. "It's amazing, isn't it, how deep imagination goes?" he says finally. "A dream like that is how a poet—one of the really great ones—must see his poem. Every detail so clear and so bright." He falls silent and the kitchen belongs to the sun and the dancing motes; outside, the world is on hold. Janet looks at the Volvo across the street; it seems to pulse in her eyes, thick as a brick. When the phone rings, she would scream if she could draw breath, cover her ears if she could lift her hands. She hears Harvey get up and cross to the nook as it rings again, and then a third time. It is a wrong number, she thinks. It has to be, because if you tell your dreams they don't come true. Harvey says, "Hello?" Rest Stop He supposed that at some point between Jacksonville and Sarasota he did a literary version of the old Clark-Kent-in-the-phone-booth routine, but he wasn't sure just where or how. Which suggested it wasn't very dramatic. So did it even matter? Sometimes he told himself the answer to that was no, the whole Rick Hardin/John Dykstra thing was nothing but an artificial construct, pure press agentry, no different from Archibald Bloggert (or whatever his real name might have been) performing as Cary Grant, or Evan Hunter (whose actual birth name had been Salvatore something-or-other) writing as Ed McBain. And those guys had been his inspiration . . . along with Donald E. Westlake, who wrote hard-boiled "caper" novels as Richard Stark, and K. C. Constantine, who was actually . . . well, no one really knew, did they? As was the case with the mysterious Mr. B. Traven, who had written Treasure of the Sierra Madre. No one really knew, and that was a large part of the fun. Name, name, what's in a name? Who, for instance, was he on his biweekly ride back to Sarasota? He was Hardin when he left the Pot o' Gold in Jax, for sure, no doubt. And Dykstra when he let himself into his canal-side house on Macintosh Road, certainly. But who was he on Route 75, as he flowed from one town to the other beneath the bright turnpike lights? Hardin? Dykstra? No one at all? Was there maybe a magic moment when the literary werewolf who earned the big bucks turned back into the inoffensive English professor whose specialty was twentieth-century American poets and novelists? And did it matter as long as he was right with God, the IRS, and the occasional football players who took one of his two survey courses? None of that mattered just south of Ocala. What did was that he had to piss like a racehorse, whoever he was. He'd gone two beers over his usual limit at the Pot o' Gold (maybe three) and had set the Jag's cruise control at sixty-five, not wanting to see any strobing red lights in his rearview mirror tonight. He might have paid for the Jag with books written under the Hardin name, but it was as John Andrew Dykstra that he lived the majority of his life, and that was the name the flashlight would shine on if he was asked for his operator's license. And Hardin might have drunk the beers in the Pot o' Gold, but if a Florida state trooper produced the dreaded Breathalyzer kit in its little blue plastic case, it was Dykstra's intoxicated molecules that would wind up inside the gadget's educated guts. And on a Thursday night in June, he would be easy pickings no matter who he was, because all the snowbirds had gone back to Michigan and he had I-75 pretty much to himself. Yet there was a fundamental problem with beer any undergraduate understood: You couldn't buy it, only rent it. Luckily, there was a rest stop just six or seven miles south of Ocala, and there he would make a little room. Meanwhile, though, who was he? Certainly he had come to Sarasota sixteen years before as John Dykstra, and it was under that name that he had taught English at the Sarasota branch of FSU since 1990. Then, in 1994, he'd decided to skip teaching summer classes and have a fling at writing a suspense novel instead. This had not been his idea. He had an agent in New York, not one of the superstuds, but an honest enough guy with a reasonable track record, who had been able to sell four of his new client's short stories (under the Dykstra name) to various literary magazines that paid in the low hundreds. The agent's name was Jack Golden, and while he had nothing but praise for the stories, he dismissed the resulting checks as "grocery money." It had been Jack who'd pointed out that all John Dykstra's published stories had "a high narrative line" (which was agentese for a plot, as far as Johnny could tell) and suggested his new client might be able to make $40,000 or $50,000 a whack writing suspense novels of a hundred thousand words. "You could do that in a summer if you found a hook to hang your hat on and then stuck to it," he'd told Dykstra in a letter. (They hadn't progressed to using the phone and the fax at that point.) "And it would be twice as much as you'd make teaching classes in the June and August sessions down there at Mangrove U. If you're going to try it, my friend, now is the time—before you find yourself with a wife and two-point-five children." There had been no potential wife on the horizon (nor was there now), but Dykstra had taken Jack's point; rolling the dice did not get easier as one grew older. And a wife and kids weren't the only responsibilities one took on as time slipped quietly by. There was always the lure of the credit cards, for instance. Credit cards put barnacles on your hull and slowed you down. Credit cards were agents of the norm and worked in favor of the sure thing. When the summer-teaching contract came in January of '94, he had returned it unsigned to the department head with a brief explanatory note: I thought this summer I'd try to write a novel instead. Eddie Wasserman's reply had been friendly but firm: That's fine, Johnny, but I can't guarantee the position will be there next summer. The man in the chair always gets right of first refusal. Dykstra had considered this, but only briefly; by then he had an idea. Better still, he had a character: The Dog, literary father of Jaguars and houses on Macintosh Road, was waiting to be born, and God bless the Dog's homicidal heart. • • • Ahead of him was the white arrow on the blue sign twinkling in his headlights, and the ramp curving off to the left, and the high-intensity arc-sodium lights illuminating the pavement so brightly that the ramp looked like part of a stage set. He put on his blinker, slowed to forty, and left the interstate. Halfway up, the ramp branched: trucks and Winnebagos to the right, folks in Jaguars straight ahead. Fifty yards beyond the split was the rest stop, a low building of beige cinder block that also looked like a stage set under the brilliant lights. What would it be in a movie? A missile-command center, maybe? Sure, why not. A missile-command center way out in the boonies, and the guy in charge is suffering from some sort of carefully concealed (but progressive) mental illness. He's seeing Russians everywhere, Russians coming out of the damn woodwork . . . or

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733, 943, 320, 7192, 326, 253, 4588, 7043, 830, 273, 253, 18722, 908, 275, 253, 12296, 778, 320, 1027, 313, 70, 15, 72, 904, 253, 18722, 778, 320, 275, 253, 308, 3788, 830, 481, 380, 36348, 778, 320, 275, 616, 7043, 830, 13, 824, 347, 271, 42391, 5148, 313, 15061, 13, 611, 13, 390, 8182, 10, 390, 40163, 552, 33322, 15, 3808, 273, 841, 7043, 4948, 13, 824, 347, 6897, 13, 403, 21917, 2130, 15, 5131, 7043, 4948, 476, 320, 1160, 970, 973, 1929, 5609, 15, 187, 688, 581, 14704, 13, 253, 275, 661, 273, 253, 1246, 3688, 19142, 27, 387, 1878, 581, 8862, 12296, 1907, 247, 7985, 1708, 32593, 273, 432, 670, 470, 15, 22232, 281, 670, 470, 15, 38447, 387, 247, 24082, 11747, 991, 273, 432, 21566, 281, 35771, 285, 387, 247, 337, 27, 22, 13, 933, 23458, 275, 1824, 28, 387, 1878, 581, 28422, 12296, 1907, 247, 7985, 1708, 32593, 273, 432, 670, 470, 15, 2904, 281, 670, 337, 15, 2417, 387, 247, 24082, 11747, 991, 273, 432, 50059, 281, 721, 1237, 285, 387, 247, 337, 27, 22, 13, 933, 23458, 275, 1824, 28, 387, 1878, 581, 4231, 20891, 12296, 1907, 247, 7985, 1708, 32593, 273, 432, 670, 470, 15, 9992, 281, 670, 470, 15, 28950, 387, 247, 24082, 11747, 991, 273, 432, 36725, 281, 28564, 285, 387, 247, 337 ]

is to provide a first ink composition comprising a first colorant, and a second ink composition comprising a second colorant and a precipitating agent (e.g., inorganic salts), which will react with the first colorant in the first ink composition so that upon contact of the first ink and the second ink on the printing medium a precipitate is formed, thus preventing color bleed between the first ink composition and the second ink composition. Likewise, many inks used commercially represent a compromise in an attempt to achieve an ink evidencing at least an adequate response in each of the aforementioned characteristics. For example, a number of inks and ink sets suffer from black to color bleed which make their use less desirable or impossible for a number of color-intensive printing applications. Likewise, many of the known inks and ink sets suffer from poor lightfastness and humid hue shift/bleed on special media. Other problems are encountered when attempting to use these known inks and ink sets in reservoir based off-axis printing systems. In view of the foregoing, there exists a need in the industry for inks that work well in both fiber and foam based off-axis systems as well as in pens/cartridges without any fiber or foam material, and for ink formulations which have improved properties and which do not improve one property at the expense of the others, such as image quality, light fastness, architecture, performance and reliability. More specifically, there exists a need for improved black-to-yellow (K/Y) bleed for faster plain paper printing, no humid hue shift/bleed for magenta inks on special media, good plain paper chroma and lightfastness, and/or compatibility of inks with new reservoir material in an ink supply (e.g., as seen in off-axis system cartridges) Color ink sets suitable for use in ink-jet printers are provided. In accordance with the invention, a set of color inks for use in printer systems are provided and formulated to provide improved plain paper and special media performance while maintaining good printing characteristics. The inks and ink sets of the present invention exhibit excellent color performance and lightfastness across a range of media, robust K/Y bleed resistance on plain paper at fast print speeds, as well as excellent printability and reliability. Furthermore, the ink set enables good reliability in an environment having a relatively high concentration of precipitating agents. This reliability enables the use of precipitation bleed control mechanisms. The inks and ink sets of the present invention also work equally well in a synthetic fiber or foambased (e.g., polyurethane foam) or a fiberless (foamless) system. More specifically, a specific dye set for formulating yellow, magenta, and cyan inks is disclosed, a yellow dye comprising a mixture of acid yellow 23 (AY23) and direct yellow 132 (DY132), a cyan dye comprising a mixture of acid blue 9 (AB9) and a cyan dye compound having the formula: xe2x80x94(SO3H)2.7 CuPcxe2x80x94(SO2NH2)0.5 xe2x80x94(SO2NH(C2H4 OH)0.8 wherein Pc represents a phthalocyanine nucleus (as disclosed in Patent Application No. WO 99/67334, the contents of which are incorporated herein by reference); and a magenta dye comprising a magenta dye compound having formula: wherein Q is a cation. The invention described herein is directed to a specific ink set for printing ink-jet images using commercially available ink-jet printers, such as DESKJET(copyright)(copyright) printers, and more particularly, off-axis ink-jet printers, such as the DESKJET 2200(copyright) printer, manufactured by Hewlett-Packard Company of Palo Alto, Calif. The ink set enables an ink-jet color printer to produce high quality color images having excellent color performance and lightfastness on a range of media, particularly on plain paper. Furthermore, the ink set enables good reliability, such as ink stability, and decap and recovery (e.g. crusting) in a variety of environments. The present yellow, magenta, and cyan aqueous ink compositions each comprise in general from about 0.05 to about 20 wt % of at least one dye and a vehicle comprising the following components (in wt % of total ink composition): from about 5 to about 30 wt % of at least one organic solvent; 0 to about 5 wt % of at least one component independently selected from the group consisting of surfactants, buffers, precipitating agents and biocides. All concentrations herein are in weight percent of total ink composition, unless otherwise indicated. The purity of all components is that employed in normal commercial practice for ink-jet inks. In the practice of the invention, each ink color, namely, yellow, magenta, and cyan can comprise more than one dye load. That is, there can be one or more ink-jet ink supplies filled for each ink color, each supply having a different dye load or a different dye. As used herein, the term xe2x80x9cinkxe2x80x9d refers to the inks of the present invention. In selecting the colorants for the ink set of the present invention, the following factors were considered: reduced or absence of humid hue shift; good color performance, particularly, on plain paper; good lightfastness; good black to color bleed resistance; excellent printability and readability; and compatibility of inks with reservoir fiber-based materials in the ink supply. Of particular importance in the present invention was the selection of appropriate colorants capable of providing the aforementioned characteristics in a reservoir-based off-axis printer, as well as providing those attributes in a printer or pen lacking such a fiber material. In order to achieve the above-mentioned goals, the dyes or colorants selected for the present ink set should exhibit good compatibility (e.g., stable in the ink vehicle) in various environments. For example, the selected colorants should exhibit little, if any, significant reactivity with precipitating agents when these two materials (i.e., colorant and precipitating agent) are formulated in the same ink and should remain soluble when formulated with a precipitating agent. In other words the dyes should have sufficient solubility in the ink vehicle so that they would not form unwanted levels of precipitate by the precipitating agents or through reaction with other components in the ink. Additionally, the dyes should not react with the precipitant to form unwanted levels of compounds that will, either immediately or over time, drop out of solution. For example the dyes should not form insoluble complexes or salts that have a tendency to form aggregates that have decreased solubility in the ink vehicle over time in such levels as to interfere with the desired performance of the printing system. The selected colorants must also exhibit good lightfastness on a wide range of media, particularly, special paper. It is also important that the colorants produce highly chromatic printed images having the appropriate hue, especially on plain paper. It was found that many of the dyes that satisfied the first two requirements, namely, good solubility and lightfastness, produced printed images that (1) deviated from the ideal hue angle targets on plain paper, and/or (2) had low chroma on plain paper. The dye set of the present invention, provides good color gamut on plain paper; good lightfastness; improved K/Y bleed, good pH stability, and good printing performance. The ink set of the present invention comprises: a yellow ink comprising a mixture of acid yellow 23 (AY23) and direct yellow 132 (DY132); a cyan ink comprising a mixture of acid blue 9 (AB9) and a cyan dye compound having the formula: xe2x80x94(SO3H)2.7 CuPcxe2x80x94(SO2NH2)0.5 xe2x80x94(SO2NH(C2H4OH)0.8 xe2x80x83wherein Pc represents a phthalocyanine nucleus; and a magenta ink comprising a magenta dye having the formula: xe2x80x83wherein Q is a cation. In a preferred embodiment, Q is independently selected the group of cations consisting of ammonium, substituted ammonium, sodium, lithium, potassium, and tetramethylammonium ion. The inks of the present invention comprise from about 0.05 to about 20% dye; preferably, from about 0.1 to about 8%; and more preferably, from about 0.5 to about 5%; by weight, based on the total weight of the ink, based on the sodium form of the dyes. It should be understood that the actual salt form of the dye used in the ink may be different (e.g., the dye may be in the TMA form). The dyes may be in their salt form, such as an alkali metal (Na, K, or Li) or quaternary ammonium. Some of these salt forms, such as Na, are commercially available. Other salt forms can be made using well known techniques. In one embodiment, the inks of the present invention comprise: at least one yellow ink having a visible light absorbance of from about 0.242 to about 0.620 at a lambdamax of from 404 to 412 and at a 1:5,000 dilution in water; at least one cyan ink having a visible light absorbance of from about 0.08 to about 1.55 at a lambdamax of from 624 to 632 and at a 1:5,000 dilution in water; at least one magenta ink having a visible light absorbance of from about 0.020 to about 0.807 at a lambdamax of from 540 to 550 and at a 1

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backgroundColor = "#008000"; } } </script> Michel Lemieux Michel Lemieux (born February 13, 1959 in Indianapolis, Indiana) is a Canadian multimedia artist from Quebec, whose career has incorporated work in theatrical design, installation art, film, video, dance and music. First coming to prominence in the early 1980s as a performance artist whose work explored the integration of new media technologies into experimental pop music in a manner similar to Peter Gabriel and Laurie Anderson, more recently he has concentrated primarily on creating, designing, directing and producing multimedia theatrical presentations for events, theatrical companies and other artists. Career A 1979 graduate of the National Theatre School of Canada, Lemieux composed music for dance and theatrical troupes including La La La Human Steps, and did performance art work in Montreal before breaking through to wider success with his 1984 show Solide Salade. The show, a complex performance piece which incorporated film and video projections, music, dance and visual and lighting design, had a successful sold-out run in Montreal before touring venues across North America, Europe and Japan. In 1986, Lemieux performed the show at Expo 86, and signed to the record label Audiogram, with whom he released a self-titled album of songs from Solide Salade. He won the CASBY Award for Most Promising Male Vocalist, was nominated for the Juno Award for Most Promising Male Vocalist at the Juno Awards of 1986, and garnered two Prix Félix nominations for Best English-Language Pop/Rock Album and Best Video ("Romantic Complications"). In 1988, he premiered his new show Mutations at the arts festival of the 1988 Winter Olympics in Calgary, Alberta, and released the album Taming the Power Inside. He toured Mutations across Canada, and at World Expo 88 in Australia. Taming the Power Inside was again a Félix nominee for Best English Pop/Rock Album. In 1990, he premiered his first works co-created with Victor Pilon instead of as a solo artist; Pilon has since been Lemieux's creative and business partner in most of his subsequent work. Their first works together were Lemieux's new performance piece Free Fall, and Le Souffle de Pythagore, a holographic video dance work which was Lemieux's first work created for another performer. In 1991, Lemieux and Pilon created In Mid Air, a theatrical piece about the then-imminent transfer of Hong Kong from British to Chinese control which was created for Hong Kong's Festival 2000. In 1992, Lemieux and Pilon created Têtes Chercheuses, a commissioned performance piece for the 25th anniversary of Montreal's Saidye Bronfman Centre, and created and designed concert performances for UZEB and Michel Rivard, while Lemieux collaborated with Richard Blackburn on the design and staging of the parade to kick off Montreal's 350th anniversary celebrations. Lemieux and Pilon have since collaborated on works including Grand Hôtel des Étrangers, the stage design and direction of the Prix Félix ceremony in 1995, theatrical adaptations of Jean Cocteau's Orféo, William Shakespeare's The Tempest and Luc Plamondon's Starmania, and Cirque du Soleil's 2006 show Delirium. Lemieux was named an Officer of the Order of Canada in 2012, and a Chévalier of the National Order of Quebec in 2014. Lemieux is openly gay. He has stated that while his work addresses universal themes rather than gay-specific ones, he does consider his sexuality to influence his creative perspective. Works As performer Le Tympan de la Cantatrice (1982) L'Oeil rechargeable/The Rechargeable Eye (1983) Solide salade (1984) Mutations (1988) Free Fall / Voix de passage (1990) As creator or director Le Souffle de Pythagore (1990) In Mid Air (1991) Têtes Chercheuses (1992) Act of Faith / Feux sacrés (1993) Grand Hôtel des Étrangers (1994) Territoire Intérieur / À mille lieux (1994) Hommage à la musique du Cirque du Soleil (1995) Reach for the Stars / La route des étoiles (1995) Pôles (1996) Time Travel / Voyage dans le temps (1997) Orféo (1998) Harmony 2000 (1999) Ocean of Hope / Océan d’espoir (1999) Translucide (2000) This is a Sphere (2000) Anima (2002) The Planets (2003) Soleil de minuit (2004) La Tempête (2005) Delirium (2006) NORMAN (2007) Starmania Opéra (2008) La Belle et la Bête (2011) Continuum - Planetarium Rio Tinto and Espace pour la vie (2013) Dreamscapes (2014) ICARUS (2014) Cité Mémoire (2016) Discography Michel Lemieux (1986)Taming the Power Inside'' (1987) References External links Category:Living people Category:1959 births Category:People from Indianapolis Category:Canadian multimedia artists Category:Canadian installation artists Category:Canadian video artists Category:Canadian theatre directors Category:Canadian theatre managers and producers Category:Canadian performance artists Category:Canadian production designers Category:Canadian experimental musicians Category:Canadian electronic musicians Category:Canadian composers Category:Canadian male composers Category:Canadian male singers Category:Artists from Montreal Category:LGBT artists from Canada Category:LGBT musicians from Canada Category:LGBT directors Category:Officers of the Order of Canada Category:Knights of the National Order of Quebec Category:Gay artists Category:Gay musicians Category:National Theatre School of Canada alumni Category:Musicians from MontrealQ: Handling array value in JS I have a problem with my arrays in JavaScript. I can't seem to get the value correctly. I create my array in PHP like this: $data = Array(); $get = mysql_query("SELECT x,y,sid FROM table WHERE uid='1'"); while($row = mysql_fetch_assoc($get)){ $data[$row['x']] = Array(); $data[$row['x']][$row['y']] = $row['sid']; } $data = json_encode($row) EDIT The json_encode comes out as "false" /EDIT I then assigned this $data to a JS variable as sdata. So then i try to get the value in JS but its not working. I get an undefined error. This is my Javascript: var i = 1; var j = 5; if(sdata["x"] == i && sdata["y"] == j){ alert(sdata["x"]["y"]["sid"]); } Its meant to alert me the value of "sid" but i get: Undefined Any ideas where my mistake is? A: Given your json alert(sdata["x"]["y"]["sid"]); should be alert(sdata["sid"]); as the json encoded data you show is only a one dimensional array EDIT If your json comes out as false, that's a different story: $data = json_encode($row); Should be inside your loop, for good practice, and if you're just encoding the $row why even bother with $data[$row['x']] = Array(); $data[$row['x']][$row['y']] = $row['sid']; Otherwise try print_r($row); within your while statement and make sure your expected result is coming through from mysql in the first place. EDIT If you are trying to get the $data variable in json then use $data = json_encode($data); outside of your loop. EDIT JSFiddle to return sid for given x and y - I'm sure it can be done in a cleaner way, but it's a start http://jsfiddle.net/HWByj/ var sdata = {"4":{"4":"1"},"7":{"1":"0"}}; var i = 4; var j = 4; if(typeof sdata[i] != 'undefined') { if(typeof sdata[i][j] != 'undefined') { alert(sdata[i][j]); //gives you the value of sid } } I'll give hints I guess>Snorunt for the climate (also looks like Moomin, popular in my particular area)>Aggron for the iron mines everywhere>Lampent for a popular urban legend>Lycanroc for the wolves starting to repopulate the state>Bergmite for the stupidly cold weather>Shellder for our invasive species problem >>38560398This is literally anywhere forested in NA though. You have to rule some common ones out next time and focus on cultural aspects. Deer and forested help us figure put it’s not desert, but the rest are pretty useless.

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-AVV- and chemerin-156-AAV-injected mice. HCC progresses from hyperplastic nodules to adenomas to carcinomas \[[@B22-ijms-21-00252],[@B23-ijms-21-00252]\]. At the time of chemerin-156 overexpression, mice had already developed preneoplastic lesions \[[@B22-ijms-21-00252],[@B23-ijms-21-00252]\]. Larger tumors originate from these hyperplastic nodules. Chemerin-156 had no effect on tumor progression. The number of large tumors and the degree of tumor malignancy did not differ between the two groups of animals. Cancer-associated fibroblasts within the HCC environment contribute to disease progression. These cells express α-SMA, which is associated with poor survival of patients with HCC \[[@B48-ijms-21-00252]\]. In the tumors, *α-SMA* was comparably induced in both groups of mice in accordance with similar malignancy of liver tumors. The HCC biomarker AFP similarly increased during disease progression in all of the mice, further illustrating comparable tumor growth. Small tumors and neoplastic lesions usually do not secrete AFP and do not affect its serum level \[[@B28-ijms-21-00252]\]. The mechanisms by which chemerin may prevent formation of liver lesions remains unknown. Liver fibrosis and bioactive lipids like ceramides contribute to the pathogenesis of liver tumors \[[@B1-ijms-21-00252],[@B44-ijms-21-00252]\]. Based on histological, gene expression, and lipidomic data, chemerin-156 did not improve liver function. Cancer is associated with adipose tissue loss, but fat pad weights were not changed by chemerin overexpression. Of note, there was a negative correlation of liver to body weight ratio and intraabdominal fat pad weights. Fat atrophy appears to be triggered by the tumor and may supply cancers with fatty acids to generate ATP \[[@B49-ijms-21-00252]\]. Overexpression of chemerin in the liver did not alter adipose tissue mass and appears not to interfere with energy supply. Chemically-induced liver tumorigenesis is a stepwise process with distinct stages of initiation, promotion, and progression \[[@B50-ijms-21-00252]\]. The current model indicates that chemerin-156 retards initiation and/or early tumor growth. The expression of three genes, *DOCK8*, *LHPP*, and *CYP1A2*, was induced in the normal liver tissues of chemerin-156-AVV compared to control-AAV infected mice. The suppression of these genes in the murine tumors and human HCC \[[@B41-ijms-21-00252],[@B42-ijms-21-00252],[@B43-ijms-21-00252]\] suggests a role in hepatocarcinogenesis. Future experiments have to evaluate a potential anti-tumor capacity of these proteins. Again, equal expression of these genes in the HCC of both animal groups showed that chemerin-156 had little or no protective role in the progression of HCC. Principally, this seems to contradict recent studies demonstrating the anti-cancer effects of this chemerin isoform in xenograft models \[[@B15-ijms-21-00252],[@B16-ijms-21-00252]\]. Compared to DEN-induced HCC, xenograft models do not develop liver fibrosis \[[@B51-ijms-21-00252]\]. Proteinases like chymase were induced in the fibrotic liver and may contribute to chemerin inactivation \[[@B52-ijms-21-00252],[@B53-ijms-21-00252]\]. Chromosomal aberrations, inter- and intra-tumor heterogeneity are prevalent in carcinogen-induced hepatocarcinogenesis \[[@B51-ijms-21-00252]\] and affect cell function. The heterogeneous sensitivity of HCC cells to drugs like sorafenib has been documented \[[@B54-ijms-21-00252]\] and the responsiveness of different HCCs to chemerin-156 may vary. Furthermore, CMKLR1 was strongly downregulated in the HCC tissues of the mice studied herein, and this may further abolish the protective effects of chemerin-156. However, CMKLR1 levels were maintained in the tumors of mice 21 weeks after DEN injection \[[@B47-ijms-21-00252]\], consistent with the ability of chemerin-156 to exert beneficial activities in early carcinogenesis. Chemerin expression was analyzed in different human cancers, whereas levels of CMKLR1 were hardly investigated. The human protein atlas provides information about CMKLR1 in colorectal, breast, prostate, lung, and thyroid cancer \[[@B55-ijms-21-00252]\]. CMKLR1 protein was not prognostic in these different tumor diseases \[[@B55-ijms-21-00252]\]. In the liver, CMKLR1 is expressed by hepatocytes, Kupffer cells, bile-duct cells, and hepatic stellate cells \[[@B56-ijms-21-00252]\]. Preliminary data from our group suggest that CMKLR1 protein was reduced in non-viral human HCC \[[@B57-ijms-21-00252]\]. Until now, the factors regulating CMKLR1 in liver cells have hardly been described. Adiponectin and IL-6 seem to induce CMKLR1 mRNA in hepatocytes. In hepatitis C infection, hepatic CMKLR1 was normal, levels were reduced or induced in NASH \[[@B5-ijms-21-00252]\]. Further research has to analyze CMKLR1 expression in HCC as well as chronic liver diseases. The contribution of serum chemerin to HCC is a further unresolved question. Patients with liver cirrhosis are at risk of developing HCC \[[@B58-ijms-21-00252]\]. Low systemic chemerin was associated with mortality in patients with decompensated disease \[[@B59-ijms-21-00252]\]. On the other hand, serum chemerin was comparable in non-cancer patients, patients with colorectal liver metastases, and HCC \[[@B60-ijms-21-00252]\]. Most chemerin in serum is inactive \[[@B61-ijms-21-00252]\], and detailed analysis of chemerin isoforms in patients with cirrhosis and HCC may help to resolve this issue. Full-length chemerin overexpression in adrenocortical carcinoma cells promoted β-catenin degradation, which was initiated by phosphorylation of the protein at S33, S37, or T41. Moreover, it inhibited the phosphorylation of p38 kinase \[[@B8-ijms-21-00252]\]. Subsequently, cell proliferation, invasion, and tumorigenesis were blocked. Interestingly, exogenously-provided active chemerin-157 had no effect on these features \[[@B8-ijms-21-00252]\]. Aberrant activation of the Wnt/β-catenin pathway was reported in liver cancer, but nuclear localization of β-catenin was not detected in the DEN model \[[@B60-ijms-21-00252]\]. Mice with hepatocytes unable to secrete Wnts had comparable tumor burden and HCC histology as the respective controls \[[@B62-ijms-21-00252]\]. These studies showed that β-catenin was dispensable during DEN-induced HCC \[[@B62-ijms-21-00252],[@B63-ijms-21-00252]\]. Indeed, protein levels of β-catenin were essentially identical in tumorous and non-tumorous tissues, and did not vary between the groups. Moreover, p38 protein and its phosphorylated form were not changed in tumors of DEN-injected mice \[[@B39-ijms-21-00252]\]. Accordingly, *p38* mRNA was not upregulated in the tumors nor by chemerin-156 overexpression. Akt was activated by chemerin in short-term exposure. Treatment with chemerin for a longer time caused a decline in the levels of phosphorylated Akt. Of note, after 4 h incubation, Akt activation reverted to the resting levels \[[@B16-ijms-21-00252]\]. There was no evidence to suggest that Akt was activated by chemerin-156 in the cancer tissues analyzed. This kinase affects various signaling pathways and nearly identical gene expression in tumor and paratumor tissues of chemerin-156-AAV- and control-AAV-infected mice argues against differential activity of Akt. This may also apply to additional proteins, including the tumor suppressors p53 and PTEN. These pathways may contribute to the reduced number of small tumors in chemerin-156-overexpressing mice which is a subject of further investigations. The Fabp5 protein in HCC is associated with worse outcome and in vitro analysis revealed higher migration, invasion, and proliferation rates of cells with high Fabp5 protein levels \[[@B64-ijms-21-00252]\]. Identical expression of Fabp5 protein in the tumors of both groups again indicated comparable malignancies. Pnpla5 is a neutral lipid triacylglycerol lipase and, furthermore, has acylglycerol transacylase activity \[[@B45-ijms-21-00252]\]. Pnpla5 mRNA was highly expressed in HCC tissues of chemerin-156-infected mice. Triglyceride and diacylglycerol species were nevertheless equally abundant in the tumors of both groups. This indicates that Pnpla5 is not a primary determinant of hepatic triglyceride and diacylglycerol levels. However, it is also possible that Pnpla5 protein and enzymatic activity were not induced in parallel to mRNA levels. It would be interesting to clarify the role of this enzyme in hepatic lipid metabolism. Elevated diacylglycerol concentrations contribute to HCC proliferation \[[@B65-ijms-21-00252]\] and identical levels in the tumors of both animal groups further exclude major differences in HCC malignancy. Normal expression of SREBP1c, FAS, and SCD1 showed that lipogenesis was not altered in the cancer tissues. HCC cells express low-density lipoprotein and very

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the same woman who thinks calling Haiti a "shithole" is racist.” It IS racist characterizing people from “shithole” brown countries as not being as worthy of immigration as the nice white nations like Norway. Try to be at least a little bit honest, but I know that’s asking too much of you. We all know what he meant. I sometimes wonder what drives you people. Xenophobia and bigotry trump (pun intended) any Christian teaching you’ve had and you easily put it on the back burner. You rationalize it, you deny it, you even revel in it like dogs rolling in shit. The smell of the comments sections are smelling particularly foul the last few days. The people from there may or may not be good individuals but that is besides the point. They have no right to immigrate here and at a time when industries are becoming increasingly automatized we do not need illiterate unskilled people. You want them here because they will vote Dem (either legally or illegally). Outside of that, they can rot in ghettos for all you care. But that such people apparently sincerely believe that les deplorables grant them any moral credibility, let alone moral authority, is one of the most fascinating studies in human delusions of the age. This phenomenon may just be a particular instance of what Haidt noted: that conservatives understand liberals but liberals don't understand conservatives, so whatever liberals are banging on about to conservatives is very often going to be off-kilter enough to end up in "wtf?" territory. Lately, though, the moral grandstanding seems to me to be developing into a form of sociopathy, rather than being a basic philosophical misunderstanding or workaday lack of self-insight. I don't understand why people who do not support the President, expect him to do for them. When HW Bush reneged on his promise of no new taxes, he not only turned his supporters against him but also turned himself into a wussy. If Trump reneges on immigration, he'll be both toast and a wussy. You read it here first.Q: Hg ACL for cloning Is it possible to use the mercurial ACL extension to prevent specific users from cloning a repository? If so, how do you do it? A: You don't need the ACL extension to prevent specific users from cloning. The allow_read and deny_read settings in the [web] section of a hgrc file grant/remove clone rights. Cloning is really just hg init ; hg pull under the covers. http://www.selenic.com/mercurial/hgrc.5.html#web Our magazine always stood against all kinds of unfair and idiotic practices around us. The provocation for this write-up is the results of International Caricature Competition organized by Indian institute of Cartoonists. Unfortunately, we happened to see those prize winning entries. It was a clear case of ‘murder’ of the caricature art form ! Undoubtedly, Rtd. Judge Mr. Venkatachalayya, artist Andani and cartoonist Keshav were responsible for this tragedy. What more can we expect when these three caricature illiterate persons become the judges ! A review of these prize winning works would turn their heads down. Section- Manmohan Singh First prize: Except for its detailed work, this one is not at all a perfect caricature.The nose is unnecessarily distorted so big. Why Gandhi specs? [ Is it Gandhism ? ha ha ha.. ] His bushy eyebrows are missing. Second prize : Mr Manmohan Singhmight fall flatif he happened to see this one ! What is the ‘hole’ thing between forehead and turban ? Third prize : Here Mr Singh was butchered beyond recognition ! All those 3 consolation entries are realistic portraits ! Section - Sonia Gandhi First,second and third prize winning entries should have beenkept out of the competition itself for it’s realistic approach.All 3 are neat portraits! These 3 consolation winning works are not perfect ones. Now, what is a caricature after all ?A portrait ? No way ! Or is it just an exaggeration face of a person ? Exaggeration of face is okay to some extent. A perfect caricaturist would show thedistorted face as well as something about the person. But judges here simply ignored all this . It’s a big humiliation for those who believed in caricaturing. IIC did a lot of valuable programmes so far. But now it lost it’s respect with this blunder. Poor R V Deshapande, President of Congress has donated Rs3,50,000 as the prize money. Sadly, the money was spent to hire realistic artists to murder this Followers VAARE KORE-visitors PRAKASH SHETTY About Me Here is a rare species called Prakash Shetty. Born on April Fools Day,1960.I was addicted to cartooning at the age of fifteen [ 1975 ] I started my funny career with a kannada magazine called Santhosha. Then switched on to a English daily - The Times Of Deccan. Later with Mungaru daily and finally served The Week. At present Iam seriously into funny business. Spot caricaturing at events..drawing huge cartoon murals... staff caricatures on 40ft wall...t-shirt cartoons...coloured family caricatures...recently Prakash Shetty PUNCH became instant hit on ETV. My last misadventure was VAARE KORE,a humour magazine in kannada language.Fun Gallery is my new baby. Call 9591979629 0r 080-28606030 email id- [email protected]<ActionBar title="Extras & Events Demo"></ActionBar> <ScrollView> <StackLayout> <StackLayout android:visibility="collapsed"> <label text="Here auto-paging is enabled with an interval of 3 seconds." textWrap="true" margin="10,5,0,5" ></label> <label text="You can capture the tap and change events." textWrap="true" margin="10,5,0,5"></label> <label text="Page-indicator can be turned on/off and its color changed" textWrap="true" margin="10,5,20,5" ></label> </StackLayout> <StackLayout ios:visibility="collapsed"> <label text="You can capture the change events." textWrap="true" margin="10,5,0,5"></label> <label text="Page-indicator can have different animations and change color" textWrap="true" margin="10,5,20,5" ></label> </StackLayout> <GridLayout height="350"> <ns:Carousel #advCarousel height="100%" width="100%" color="white" (pageChanged)="pageChangedEvent($event)" indicatorColor="#fff" indicatorColorUnselected="#50ffffff" ios:autoPagingInterval="3" android:indicatorAnimation="swap" > <ns:CarouselItem *ngFor="let item of items" verticalAlignment="middle" [backgroundColor]="item.color" (tap)="pageTappedEvent($event)" > <GridLayout> <image [src]="item.image" stretch="aspectFill"></image> <label [text]="item.title" horizontalAlignment="center" backgroundColor="#50000000" height="30"></label> </GridLayout> </ns:CarouselItem> </ns:Carousel> </GridLayout> <label text="Indicator animation type: 'swap'" textWrap="true" ios:visibility="collapsed" margin="10,0,0,0"></label> <button text="Toggle indicator" (tap)="toggleIndicator()" margin="10,10,0,10" android:visibility="collapsed" ></button> <button text="Toggle indicator color" (tap)="toggleColor()" margin="10,10,0,10"></button> <label [text]=" 'Selected page: ' + currentPage" textWrap="true" margin="10,0,0,0"></label> <label [text]=" 'Tapped page: ' + tappedPage" textWrap="true" margin="0,0,0,0"></label> </StackLayout> </ScrollView> Pisces-Ferrum Phos– (Iron Phosphate) early inflammation–fever, start of throat and ear swelling and pain. Can stop hemorrhage, nosebleed. Use liberally in children's ailments Aquarius-Nat Mur–(Sodium Chloride or salt)- controls the water distribution of the body–so think of it for edema,

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) => { body.client = {type: 'WEB', id: 'RMV', name: 'webapp'} body.ext = 'RMV.1' body.ver = '1.18' body.auth = {type: 'AID', aid: 'x0k4ZR33ICN9CWmj'} return body } const hvvProfile = { locale: 'de-DE', timezone: 'Europe/Berlin', endpoint: 'https://www.rmv.de/auskunft/bin/jp/mgate.exe', transformReqBody, products, trip: true, radar: true, refreshJourney: true, reachableFrom: true } module.exports = hvvProfile Rules of the Game: Earnings Road Race It's another big week for earnings, with a little over half of the S&P 500 companies having delivered results thus far. Analysts are eyeing an overall year-over-year decline of 0.04% for the companies remaining. Of course, companies often set low expectations, so they will have a beat when reporting time rolls around. After Monday's bell, the beleaguered Herbalife (HLF) will deliver first-quarter results. Despite the fascination swirling around the company and the "he said, he said" battle between big activist investors, I'm just not interested. The stock continues to struggle, and even an earnings beat won't be enough to convince me of its viability at this time. While the chattering class will undoubtedly be preoccupied with Herbalife, I'll be watching some S&P names that report after the close. Hertz (HTZ) is one of our holdings. The stock has been delivering growth-style price appreciation since November. It's rallied above its 10-week average since then, rising to a new peak of $24.31 on Friday. Hertz is just on the verge of driving into large-cap land. Rival Avis (CAR) is also trading in new high ground. It has a market capitalization of nearly $9.7 billion. It has excellent liquidity, moving about 7.9 million shares per day, on average. This stock, however, has a high beta of1.80. Trade has been orderly as Hertz rallied to new highs in recent months, but a glance at the chart shows some erratic trading patterns in the not-so-distant past.This type of action is maddening for traders. But for investors with a longer time horizon, it's often wise to sit through some corrections, and even view pullbacks as opportunities to add shares. When Hertz reports after Monday's bell, analysts expect per-share income of $0.17 on revenue of $2.39 billion. Those would be increases over the year-ago quarter. Hertz beat views in each of the past four quarters. Looking at the current price, many investors would probably conclude that a pullback is due soon. Perhaps, but take a glance at the price-to-earnings ratio of 17, which suggests that this stock is not yet in "priced for perfection" mode, and appears to have some driving room ahead. Hertz closed Friday at $24.19a share. Also reporting after Monday's close is S&P 500 component Jacobs Engineering (JEC). Jacobs provides design, engineering and architectural services to corporate and government clients. This is also a mid-cap, with a market capitalization of $6.7 billion. It trades about 1 million shares per day, and has a beta of 1.46. This chart, too, indicates some wide-and-loose trading patterns that undoubtedly vex many traders. Jacobs has been in a correction since retreating from its March 28 high of $56.53. While momentum traders certainly would avoid this stock based on the technicals, the fundamentals merit a look. Analysts expect the company to report earnings per share of $0.83 on revenue of $2.93 billion, year-over-year increases on the top and bottom lines. The stock regained its 50-day line last week, and closed Friday at $51.65, 0.3%, above that key price line. For the year, analysts expect earnings of $3.33 per share, a gain of 13% over 2012. Consensus estimates were recently lowered, but the stock nonetheless appears to have good potential, based on the fundamentals.var R = require('../../../../dist/rambda.js'); var eq = require('./shared/eq'); describe('lastIndexOf', function() { var input = [1, 2, 3, 4, 5, 1]; var list = ['a', 1, 'a']; list[-2] = 'a'; // Throw a wrench in the gears by assigning a non-valid array index as object property. it('has R.equals semantics', function() { function Just(x) { this.value = x; } Just.prototype.equals = function(x) { return x instanceof Just && R.equals(x.value, this.value); }; eq(R.lastIndexOf(0, [-0]), -1); eq(R.lastIndexOf(-0, [0]), -1); eq(R.lastIndexOf(NaN, [NaN]), 0); eq(R.lastIndexOf(new Just([42]), [new Just([42])]), 0); }); it('dispatches to `lastIndexOf` method', function() { function Empty() {} Empty.prototype.lastIndexOf = R.always(-1); function List(head, tail) { this.head = head; this.tail = tail; } List.prototype.lastIndexOf = function(x) { var idx = this.tail.lastIndexOf(x); return idx >= 0 ? 1 + idx : this.head === x ? 0 : -1; }; var list = new List('b', new List('a', new List('n', new List('a', new List('n', new List('a', new Empty() ) ) ) ) ) ); eq(R.lastIndexOf('a', 'banana'), 5); eq(R.lastIndexOf('x', 'banana'), -1); eq(R.lastIndexOf('a', list), 5); eq(R.lastIndexOf('x', list), -1); }); it('finds function, compared by identity', function() { var f = function() {}; var g = function() {}; var list = [g, f, g, f]; eq(R.lastIndexOf(f, list), 3); }); });Most Helpful Positive Review Dec 02, 2009 It was a really good starter recipe. I added a bit to the ingrients, pickling salt, and changed the cooking method a bit.....I added a few spices like dill and basil, for just a little extra and added all sorts of different peppers esp hotter ones like chili peppers to give it a bit of color and extra kick since the vinegar and cooking will take away the heat of the peppers. BTW, if you don't like the heat of the peppers, you can add a little oil to the bottom of the jars before filling and it will help to take away some of the kick of the peppers! I also put some pickling salt in the vinegar/water before boiling, just a TBSP or so. Takes away a bit of the sour taste some might get. I also filled the jars differently, making it a lot easier and a lot less dangerous in my opinion. Instead of actually cooking the peppers, onions, garlic, and spices with the Vinegar/Water; I stuff them into clean jars and poured the really hot vinegar/water mixture over them. I then re-cooked the jar with lids on to make them seal, like the recipe. This allowed the peppers to cook in the jars through the boiling process, but not lose as much heat and crunch. It was also a little easier in my opinion, allowing me to stuff my jar completely with the cool, just cut ingredients, instead of having to ladle and stuff hot peppers into the jars, making sure they were filled and not burning myself in the process. Hope that helps and thanks for the great idea! Whew! I made these with a bunch of jalapenos and 2 cayenne peppers. I did throw in some evoo and fresh herbs as suggested by another reviewer. I also threw in some cherry tomatoes and green onions after I removed the pan from the heat -- I think you could pickle alomost anything in this mixture. I had some of the mixture left that wouldn't fit in the jars, so I added some more peppers for a few minutes, added 1/4 c. sugar and 1 T. salt, tossed it in the blender, and made some kickin' hot sauce. Simple recipe and pretty in the jars, too. A very simple and easy recipe. I use it to pickle banana peppers from my garden. I

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com/videojs/video.js/pull/2427)) * @misteroneill restore videojs.formatTime ([view](https://github.com/videojs/video.js/pull/2420)) * @misteroneill include child components with `true` in options ([view](https://github.com/videojs/video.js/pull/2424)) * @misteroneill create video.novtt.js in dist builds ([view](https://github.com/videojs/video.js/pull/2447)) * @misteroneill pass vtt.js option to tech ([view](https://github.com/videojs/video.js/pull/2448)) * @forbesjo updated the sauce labs config and browser versions ([view](https://github.com/videojs/video.js/pull/2450)) * @mmcc made sure controls respect muted attribute ([view](https://github.com/videojs/video.js/pull/2408)) * @dmlap switched global options back to an object at videojs.options ([view](https://github.com/videojs/video.js/pull/2461)) * @ogun fixed a typo in the Turkish translation ([view](https://github.com/videojs/video.js/pull/2460)) * @gkatsev fixed text track errors on dispose and in cross-browser testing ([view](https://github.com/videojs/video.js/pull/2466)) * @mmcc added type=button to button components ([view](https://github.com/videojs/video.js/pull/2471)) * @mmcc Fixed IE by using setAttribute to set 'type' property ([view](https://github.com/videojs/video.js/pull/2487)) * @misternoneill fixed vertical slider issues ([view](https://github.com/videojs/video.js/pull/2469)) * @gkatsev moved default and player dimensions to style els at the top of HEAD ([view](https://github.com/videojs/video.js/pull/2482)) * @gkatsev moved default and player dimensions to style els at the top of HEAD el ([view](https://github.com/videojs/video.js/pull/2482)) * @gkatsev removed non-default track auto-disabling ([view](https://github.com/videojs/video.js/pull/2475)) * @gkatsev exported event helpers on videojs object ([view](https://github.com/videojs/video.js/pull/2491)) * @nickygerritsen fixed texttrack handling in IE10 ([view](https://github.com/videojs/video.js/pull/2481)) * @gkatsev deep clone el for iOS to preserve tracks ([view](https://github.com/videojs/video.js/pull/2494)) * @forbesjo switched automated testing to BrowserStack ([view](https://github.com/videojs/video.js/pull/2492)) * @gkatsev fixed nativeControlsForTouch handling. Defaults to native controls on iphone and native android browsers. ([view](https://github.com/videojs/video.js/pull/2499)) * @heff fixed cross-platform track tests by switching to a fake tech ([view](https://github.com/videojs/video.js/pull/2496)) * @gkatsev improved tech controls listener handling. ([view](https://github.com/videojs/video.js/pull/2511)) * @dmlap move seek on replay into the flash tech ([view](https://github.com/videojs/video.js/pull/2527)) * @dmlap @gkatsev improve Flash tech error property and add an error setter to the base tech ([view](https://github.com/videojs/video.js/pull/2517)) * @dmlap update to videojs-swf 5.0.0-rc1 ([view](https://github.com/videojs/video.js/pull/2528)) * @dmlap expose start and end buffered times ([view](https://github.com/videojs/video.js/pull/2501)) * @heff fixed a number of console errors after testing ([view](https://github.com/videojs/video.js/pull/2513)) * @gkatsev made the sass files available via npm in src/css ([view](https://github.com/videojs/video.js/pull/2546)) * @heff removed playerOptions from plugin options because it created an inconsistency in plugin inits ([view](https://github.com/videojs/video.js/pull/2532)) * @heff added a default data attribute to fix the progress handle display in IE8 ([view](https://github.com/videojs/video.js/pull/2547)) * @heff added back the default cdn url for the swf ([view](https://github.com/videojs/video.js/pull/2533)) * @gkatsev fixed the default state of userActive ([view](https://github.com/videojs/video.js/pull/2557)) * @heff fixed event bubbling in IE8 ([view](https://github.com/videojs/video.js/pull/2563)) * @heff cleaned up internal duration handling ([view](https://github.com/videojs/video.js/pull/2552)) * @heff fixed the UI for live streams ([view](https://github.com/videojs/video.js/pull/2557)) * @gkatsev updated opacity of caption settings background color ([view](https://github.com/videojs/video.js/pull/2573)) * @gkatsev made all sass variables !default ([view](https://github.com/videojs/video.js/pull/2574)) * @heff fixed the inline volume control and made it the default ([view](https://github.com/videojs/video.js/pull/2553)) * @forbesjo fixed webkit deprecation warnings ([view](https://github.com/videojs/video.js/pull/2558)) * @forbesjo added Android and iOS browser testing ([view](https://github.com/videojs/video.js/pull/2538)) * @heff improved css selector strengths ([view](https://github.com/videojs/video.js/pull/2583)) * @heff moved scss vars to be private ([view](https://github.com/videojs/video.js/pull/2584)) * @heff added a fancy loading spinner ([view](https://github.com/videojs/video.js/pull/2582)) * @gkatsev added a mouse-hover time display to the progress bar ([view](https://github.com/videojs/video.js/pull/2569)) * @heff added an attributes argument to createEl() ([view](https://github.com/videojs/video.js/pull/2589)) * @heff made tech related functions private in the player ([view](https://github.com/videojs/video.js/pull/2590)) * @heff removed the loadedalldata event ([view](https://github.com/videojs/video.js/pull/2591)) * @dmlap switched to using raynos/xhr for requests ([view](https://github.com/videojs/video.js/pull/2594)) * @heff Fixed double loadstart and ready events ([view](https://github.com/videojs/video.js/pull/2605)) * @gkatsev fixed potential double default style elements ([view](https://github.com/videojs/video.js/pull/2619)) * @imbcmdth extended createTimeRange to support multiple timeranges ([view](https://github.com/videojs/video.js/pull/2604)) * @misteroneill rename "extends" to "extend" for ie8 ([view](https://github.com/videojs/video.js/pull/2624)) * @forbesjo removed the PhantomJS dependency ([view](https://github.com/videojs/video.js/pull/2622)) * @misteroneill re-exposed videojs.TextTrack ([view](https://github.com/videojs/video.js/pull/2625)) * @heff removed a second copy of video.novtt.js from dist ([view](https://github.com/videojs/video.js/pull/2630)) * @heff fixed timeranges deprecation warnings in tests ([view](https://github.com/videojs/video.js/pull/2627)) * @misteroneill

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/(-162) - 6/9. 3, 19 List the prime factors of (-1 + -3)*-1*(57 + -34). 2, 23 Suppose -2*z - 27 = 5. Let b = 34 - z. What are the prime factors of b? 2, 5 Suppose -101*s = -107*s - 204. Suppose -2*p - p = 5*o - 243, 3*o - 173 = 5*p. Let f = o + s. List the prime factors of f. 17 Let k(t) = t + 3. Let c be k(-7). Let m be (c/6)/((-2)/(-75)). Let l = 16 - m. What are the prime factors of l? 41 List the prime factors of 13/((-65)/(-2))*229*5. 2, 229 Let v(x) = x**2 - 7*x + 9. Suppose 3*k = 7*k - 5*r - 9, -2*r - 24 = -5*k. Let j be v(k). Suppose -i = -j*i + 12. What are the prime factors of i? 2, 3 Let n be (13 + -11)*(-8)/2. Let z be (-27)/12 - 2/n. List the prime factors of z + -2 + 3 + 11. 2, 5 List the prime factors of 70908/30 - 15/25. 17, 139 Let d(b) = -3*b + 10. Let f = 22 + -36. What are the prime factors of d(f)? 2, 13 Let s be 2 - 8 - (-3)/1. What are the prime factors of (356/8)/(s/(-6))? 89 Let x be ((-64)/6)/((-8)/12). Let n be (-3 + 7)*4/x. What are the prime factors of n*16*3/6? 2 Let u(m) = 3*m**3 + 8*m**2 + 2*m - 1. Let p(q) = q**2 - 1. Let w(l) = 4*p(l) - u(l). List the prime factors of w(-4). 7, 19 Let z(p) = p**2 + p - 32. Let q be z(-7). Let j(b) = b**3 - 4*b**2 + 4*b + 1. Let l be j(3). Let t = q - l. What are the prime factors of t? 2, 3 Suppose 3*j - 44 = -y, 2*y = -4*j - 6 + 64. Let v = 17 - j. Suppose 5*u - 60 = v*u. List the prime factors of u. 2, 5 Let o be ((-96)/(-14))/((-4)/(-42)). Suppose 0 = -p - 2*p - o. What are the prime factors of (-4)/(((-3)/p)/(-1))? 2 What are the prime factors of -2*(-1 - 1) + 1 + 2694? 2699 Let r(k) = 18*k + 49. List the prime factors of r(38). 733 Suppose 9 = 6*s + 3*s. Let t(c) = 54*c**2 - 2*c + 3. List the prime factors of t(s). 5, 11 List the prime factors of (1510/30)/((-1)/(-1 - 20)). 7, 151 Let w = -630 + 428. List the prime factors of (2/(-4))/(1/w). 101 Let m(t) = t + 1. Let d be m(-2). Let g(q) = q**2 + 7*q + 17. Let s be g(-4). Let r = s - d. What are the prime factors of r? 2, 3 Let n = -293 + 710. What are the prime factors of n? 3, 139 Let s = 1133 + -892. What are the prime factors of s? 241 Suppose -2*a - 284 + 4040 = 0. What are the prime factors of a? 2, 3, 313 Let d(x) = x**2 - 3*x - 3. Let r be d(4). Let g(a) = -4*a**2 + 7 + 12*a**3 - 2 + 2*a + 2*a**2 - 6. What are the prime factors of g(r)? 11 Let p be (0 + 52/4)/((-2)/(-88)). Suppose -12*u + 124 = -p. What are the prime factors of u? 2, 29 Let q = 7559 + -2774. List the prime factors of (q/12)/5 - (-3)/(-4). 79 Let n(z) = -3*z - 11. Let q be n(-5). Suppose 0 = -2*j - 2*d + 48, 3*j + 24 = q*j - 2*d. What are the prime factors of j? 2, 3 Let k(u) = -1598*u - 129. List the prime factors of k(-3). 3, 5, 311 Suppose 35299 = 17*d - 41490. List the prime factors of d. 4517 Let b(r) = -r**2 + 2*r - 1. Let j be b(3). Let f be 4 + (-3 - -3) - j. List the prime factors of (2/(-8))/(f/(-1504)). 47 Suppose -39*w + 32*w + 2184 = 0. What are the prime factors of w? 2, 3, 13 Suppose 18*a = 4*o + 16*a - 3878, -966 = -o + 4*a. List the prime factors of o. 2, 5, 97 Let g be -1 + (-3 - 2) - 3. Let s(a) = a**3 + 10*a**2 + 3*a - 16. List the prime factors of s(g). 2, 19 Let n be (-2)/6 + (-120)/(-9). Suppose r - 28 = -3*r. Let i = n - r. What are the prime factors of i? 2, 3 Let t(q) = q**3 + 3*q**2 + 5*q + 3. Let o be t(-3). Let g(p) = p**3 + 13*p**2 + 6*p + 3. What are the prime factors of g(o)? 3, 5 What are the prime factors of 26625/24 + (-81)/216? 1109 Let h be -1*8/4 - -14. Let r be 30/h - 6/(-4). Suppose -4*i + 21 + 7 = c, -r*c + 133 = -5*i. List the prime factors of c. 2 Let w be 2*(-3)/18*-15. Let t = w + -5. Suppose 5*u + 0*u - 30 = t. What are the prime factors of u? 2, 3 Let f(i) = -i**3 + 12*i**2 - 15*i - 8. Let a(q) = q**2 - q + 1. Let u(y) = a(y) - f(y). List the prime factors of u(10). 7 Let c be 14/56 + (-322)/8. Let f = -4 + 2. What are the prime factors of (56/c)/(f/10)? 7 Let s(p) = p**2 + 7*p + 2. Let l be s(-7). Suppose 2*k = -l*k. Suppose k*z + 116 = 4*z. What are the prime factors of z? 29 Suppose 0 = u - 2*k - 2229, -16*u + 11*u = 3*k - 11132. List the prime factors of u. 17, 131 Let g(h) be the third derivative of 6*h**2 + 0*h - 19/12*h**4 - 1/6*h**3 + 0. List the prime factors of g(-1). 37 Suppose 0 = 30*p - 26*p - 248. Suppose l - p = -i - 0*i, 0 = -5*l - 4*i + 309. What are the prime factors of l? 61 List the prime factors of 50/150 - 299/(-3). 2, 5 Suppose 0 = -2*j + 5*i + 1643, -1673 = -2*j - 5*i - 0*i. List the prime factors of j. 829 What are the prime factors of 1 + -11 + 3852 + -1? 23, 167 Let y be 6*(3 - (-28)/(-12)). Suppose y*k = 4*j - 3*j - 51, -j + 26 = k. List the prime factors of j. 31 Let f(h) = -1597*h - 230. What are the prime factors of f(-2)? 2, 3, 13, 19

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gh", //should userId be automatically generated or I have to enter here } I know slug is generated automatically but what about the user info? I'm getting confused here? And how do I get user info from userId? (I have a route /users/:id though but don't know how to use it in this case) User Model const userSchema = new Schema({ username: { type: String, required: true }, email: { type: String, required: true }, password: { type: String, required: true }, }, { timestamps: true }) Post Model const postSchema = new Schema({ title: { type: String, required: true }, description: { type: String, required: true }, userId: { type: Schema.Types.ObjectId, ref: "User" }, slug: { type: String, slug: "title" } }, { timestamps: true } authmiddleware.js function generateToken(payload) { return jwt.sign(payload, "secret") } function verifyToken(req, res, next) { const token = req.headers.Authorization if (!token) return res.json({ msg: "unauthorized"}) jwt.verify(token,"secret",(err, decoded) => { if (err) return res.json({ error: "unuthorized" }) req.user = decoded next() }) } module.exports = {generateToken, verifyToken } routes/posts.js router.post("/new", authmiddleware.verifyToken, postControllers.newPost) postControllers/newPost.js newPost: (req, res) => { Post.create(req.body, (err, newPost) => { if (err) console.log(err) if (!newPost) { return res.json({ message: "No post found" }) } else if (newPost) { return res.json({ post: newPost }) } }) } When I checked in postman by entering this info as body(and sent token in headers) { "title": "My first post", "description": "My first post description" } I got this result: { "post": { "_id": "5e3028ded3e24b55e06baaf2", "title": "My first post", "description": "My first post description" "createdAt": "2020-01-28T12:28:14.331Z", "updatedAt": "2020-01-28T12:28:14.331Z", "slug": "my-first-post", "__v": 0 } } But I also want to get the user info in this. Update: So, I got the userId in the newly created post object. I was doing this earlier: newPost: (req, res) => { Post.create(req.body, req.user.userId, (err, newPost) => { if (err) console.log(err) if (!newPost) { return res.json({ message: "No post found" }) } else if (newPost) { return res.json({ post: newPost }) } }) } And got and error: { "error": { "message": "Parameter \"obj\" to Document() must be an object, got 5e2f365d41ff66569445eec2", "name": "ObjectParameterError" } } Then I did this I got the result: newPost: (req, res) => { const data = { title: req.body.title, description: req.body.description, userId: req.user.userId } Post.create(data, (err, newPost) => { if (err) console.log(err) if (!newPost) { return res.json({ message: "No post found" }) } else if (newPost) { return res.json({ post: newPost }) } }) } It shouldn't be happening. No? A: You can put the logged in user's id to the request in your auth middleware, and acccess the user id in your route. Let's say you have a such auth middleware: const jwt = require("jsonwebtoken"); module.exports = function(req, res, next) { let token; if ( req.headers.authorization && req.headers.authorization.startsWith("Bearer") ) { token = req.headers.authorization.split(" ")[1]; } if (!token) return res.status(401).send("Access denied. No token provided."); try { const decoded = jwt.verify(token, "JWT_PRIVATE_KEY"); req.user = decoded; next(); } catch (ex) { res.status(400).send("Invalid token."); } }; I assume you send the authorization token in the Authorization header in the format Bearer TOKEN....... If you send the token in a different header, you need to adjust code to read token accordingly. Now when you apply this middleware to your route, you can read the user id from request, and use it. const Post = require("../models/post"); const auth = require("../middleware/auth"); router.post("/posts", [auth], async (req, res) => { const result = await Post.create({ title: req.body.title, description: req.body.description, user: req.user._id //comes from auth middleware }); res.send(result); }); For this to work, you need to include the user id in the token when you sign it. const token = jwt.sign({ _id: user._id }, "JWT_PRIVATE_KEY"); Scalable memory allocation using jemalloc - Anon84 http://www.facebook.com/note.php?note_id=480222803919 ====== gnosis Previously on HN: <http://news.ycombinator.com/item?id=1258935> Q: Elementary Submodels in Set Theory I was reading the following summary on elementary submodels: http://boolesrings.org/mpawliuk/2012/01/26/a-practical-guide-to-using-countable-elementary-submodels/ Say $M\prec N$. The link above indicates (Super Useful Fact) that any set definable by parameters in $M$ is an element of $M$. In particular, let $\phi(v_1,v_2)$ be a first order formula of set theory. My understanding of this is that, if $x\in M$ and $\{t: t\in N\wedge \phi(x,t)\}\in N$, then $\{t: t\in M\wedge \phi(x,t)\}\in M$. What I am wondering is whether we can guarantee that $\{t: t\in M\wedge \phi(x,t)\}\subset M$. As a first order sentence, we have ($\exists z) \ (\forall t)t\in z\leftrightarrow(\phi(x,t))$ Assuming this is satisfied by $N$, it must be satisfied by $M$ since $M\prec N$. In particular, there exists $z'\in M$ such that $(\forall t\in M)t\in z'\leftrightarrow(\phi(x,t))$. Certainly, $z'$ is a subset of the class we want but perhaps it contains elements which are not in $M$. Can we guarantee that $z'\subset M$? A: This all comes from the definition of elementary, and is a little more delicate than you might think. Model theoretically, a model $M$ is an elementary submodel of a model $N$ if $M$ is a submodel of $M$ (the universe of $M$ is a subset of that of $N$, and all interpretations of function/predicate/constant symbols are just the restrictions of those of $N$), and every statement about the elements of $M$ is true in $N$ iff it is true in $M$; meaning that given a formula $\varphi ( x_1 , \ldots , x_n )$ and $a_1 , \ldots , a_n \in M$, $$M \models \varphi ( a_1 , \ldots , a_n ) \Leftrightarrow N \models \varphi ( a_1

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was done on the fly as the German advance was already sweeping through the Soviet border zone. The German invasion also hampered the effectiveness of the Soviet response by shattering their communications in the war's early stages; many Soviet leaders were unable to gather reliable information about the positions of German forces until it was too late to effect an orderly evacuation. There was also a desire on the part of Soviet officials to forestall any evacuations until it was absolutely necessary, the marching orders were often to continue factory production until the eve of occupation before hurriedly dismantling and transporting factory equipment, and destroying what couldn't be moved in time. As a result of the delay in evacuations, they were often carried out under German aerial bombardment, which led to additional confusion among the frightened citizenry. Historian Rebecca Manley describes these early evacuations as being charactered by “three phenomena: the 'flight' of officials, the flight of the population, and 'panic'”. The early flight of Soviet officials who were supposed to manage the evacuation was roundly condemned by Soviet leaders, but often their retreat resulted from a realisation that evacuation procedures had started too late, and that there was no way to effectively execute it. Additionally, Soviet officials who remained in a city captured by German forces feared execution by Nazis on the hunt for communists. Avoiding that, the officials knew that they would be subject to intense interrogation as to what happened by suspicious Soviets upon returning to the fold. Despite these setbacks in the implementation of evacuation policy early in the war, around 12 million Soviet citizens successfully evacuated in 1941, even if a number of these were the result of disorganised, “spontaneous self-evacuation,” and another 4.5 million evacuated the following year. In addition, the factories that were successfully evacuated to the Central Asian rear would help provide the productive capacity the Soviets needed to eventually win the war, as well as preventing the Germans from acquiring additional industrial resources. By providing a safe haven from the German advance for Soviet citizens, Central Asia played a critical role in securing Allied victory. The evacuation itself was only part of the difficulty, however, as evacuees arriving in Central Asia faced many trials and tribulations. Due to the haphazard nature of evacuation, many labourers did not arrive with their factory, and had to find labour on their own, though jobs were hard to come by. Additionally, cities like Tashkent became overwhelmed at the sheer volume of people arriving at its gates and had great difficulty supplying the food and shelter necessary for evacuees. Upon arrival, many evacuees died of illness or starvation in extreme poverty in Central Asia. Uzbek officials set up aid stations at Tashkent, which were mirrored at other railway stations to help combat the poverty, but they could only do so much as little could be spared economically for the war effort. Despite these troubles, the ability of Central Asia to absorb Soviet industry and population to the extent that it did and in the harried manner that it did was impressive. The Germans certainly didn't foresee the preparedness of Soviet Central Asia, and in the end they paid dearly for it. Since 1991 From 1988 to 1992, a free press and multi-party system developed in the Central Asian republics as perestroika pressured the local Communist parties to open up. What Svat Soucek calls the "Central Asian Spring" was very short-lived, as soon after independence former Communist Party officials recast themselves as local strongmen. Political stability in the region has mostly been maintained, with the major exception of the Tajik Civil War that lasted from 1992 to 1997. 2005 also saw the largely peaceful ousting of Kyrgyz president Askar Akayev in the Tulip Revolution and an outbreak of violence in Andijan, Uzbekistan. Much of the population of Soviet Central Asia was indifferent to the collapse of the Soviet Union, even the large Russian populations in Kazakhstan (roughly 40% of the total) and Tashkent, Uzbekistan. Aid from the Kremlin had also been central to the economies of Central Asia, each of the republics receiving massive transfers of funds from Moscow. Independence largely resulted from the efforts of the small groups of nationalistic, mostly local intellectuals, and from little interest in Moscow for retaining the expensive region. While never a part of the Soviet Union, Mongolia followed a somewhat similar path. Often acting as the unofficial sixteenth Soviet republic, it shed the communist system only in 1996, but quickly ran into economic problems. See: History of independent Mongolia. The economic performance of the region since independence has been mixed. It contains some of the largest reserves of natural resources in the world, but there are important difficulties in transporting them. Since it lies farther from the ocean than anywhere else in the world, and its southern borders lay closed for decades, the main trade routes and pipelines run through Russia. As a result, Russia still exerts more influence over the region than in any other former Soviet republics. Nevertheless, the rising energy importance of the Caspian Sea entails a great involvement in the region by the US. The former Soviet republics of the Caucasus now have their own US Special Envoy and inter-agency working groups. Former US Secretary of Energy Bill Richardson had claimed that "the Caspian region will hopefully save us [the US] from total dependence on Middle East oil". Some analysts, such as Myers Jaffe and Robert A. Manning, estimate however that US' entry into the region (with initiatives such as the US-favored Baku-Tbilisi-Ceyhan pipeline) as a major actor may complicate Moscow's chances of making a decisive break with its past economic mistakes and geopolitical excesses in Central Asia. They also regard as a myth the assertion that Caspian oil and gas will be a cheaper and more secure alternative to supplies from the Persian Gulf. Despite these reservations and fears, since the late 1980s, Azerbaijan, Kazakhstan, and Turkmenistan have gradually moved to centre stage in the global energy markets and are now regarded as key factors of the international energy security. Azerbaijan and Kazakhstan in particular have succeeded in attracting massive foreign investment to their oil and gas sectors. According to Gawdat Bahgat, the investment flow suggests that the geological potential of the Caspian region as a major source of oil and gas is not in doubt. Russia and Kazakhstan started a closer energy co-operation in 1998, which was further consolidated in May 2002, when Presidents Vladimir Putin and Nursultan Nazarbayev signed a protocol dividing three gas fields – Kurmangazy, Tsentralnoye, and Khvalynskoye – on an equal basis. Following the ratification of bilateral treaties, Russia, Kazakhstan and Azerbaijan declared that the northern Caspian was open for business and investment as they had reached a consensus on the legal status of the basin. Iran and Turkmenistan refused however to recognise the validity of these bilateral agreements; Iran is rejecting any bilateral agreement to divide the Caspian. On the other hand, US' choices in the region (within the framework of the so-called "pipeline diplomacy"), such as the strong support of the Baku pipeline (the project was eventually approved and was completed in 2005), reflect a political desire to avoid both Russia and Iran. Increasingly, other powers have begun to involve themselves in Central Asia. Soon after the Central Asian states won their independence, Turkey began to look east, and a number of organizations are attempting to build links between the western and eastern Turks. Iran, which for millennia had close links with the region, has also been working to build ties and the Central Asian states now have good relations with the Islamic Republic. One important player in the new Central Asia has been Saudi Arabia, which has been funding the Islamic revival in the region. Olcott notes that soon after independence Saudi money paid for massive shipments of Qur'ans to the region and for the construction and repair of a large number of mosques. In Tajikistan alone an estimated 500 mosques per year have been erected with Saudi money. The formerly atheistic Communist Party leaders have mostly converted to Islam. Small Islamist groups have formed in several of the countries, but radical Islam has little history in the region; the Central Asian societies have remained largely secular and all five states enjoy good relations with Israel. Central Asia is still home to a large Jewish population, the largest group being the Bukharan Jews, and important trade and business links have developed between those that left for Israel after independence and those remaining. The People's Republic of China sees the region as an essential future source of raw materials; most Central Asian countries are members of the Shanghai Cooperation Organization. This has affected Xinjiang and other parts of western China that have seen infrastructure programs building new links and also new military facilities. Chinese Central Asia has been far from the centre of that country's economic boom and the area has remained considerably poorer than the coast. China also sees a threat in the potential of the new states to support separatist movements among its own Turkic minorities. One important Soviet legacy that has only gradually been appreciated is the vast ecological destruction. Most notable is the gradual drying of the Aral Sea. During the Soviet era, it was decided that the traditional crops of melons and vegetables would be replaced by water-intensive growing of cotton for Soviet textile mills. Massive irrigation efforts were launched that diverted a considerable percentage of the annual inflow to the sea, causing it to shrink steadily. Furthermore, vast tracts of Kazakhstan were used for nuclear testing, and there exists a plethora of decrepit factories and mines. In the first part of 2008 Central Asia experienced a severe energy crisis, a shortage of both electricity and fuel, aggravated by abnormally cold temperatures, failing infrastructure,

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ohistochemical tests revealed that the neoplastic cells were immunoreactive for S-100 and vimentin and showed no staining with cytokeratin. The animal had a local recurrence of the tumor 3 months after the initial excision. This is the first case of malignant melanoma with osteoid formation reported in animals.const createEvent = require("aws-event-mocks"); const SnsEvent = require("../src/SnsEvent"); const createSnsEvent = message => { return createEvent({ template: "aws:sns", merge: { Records: [ { Sns: { Subject: "the subject", Message: message } } ] } }); }; describe("SnsEvent", () => { describe("#message", () => { it("should be able to parse from raw event", async () => { const snsEvent = SnsEvent.fromRaw(createSnsEvent("plain text")); expect(snsEvent.message).toEqual("plain text"); expect(snsEvent.subject).toEqual("the subject"); }); it("should automatically parse JSON", async () => { const snsEvent = SnsEvent.fromRaw( createSnsEvent(JSON.stringify({ foo: "bar" })) ); expect(snsEvent.message).toEqual({ foo: "bar" }); }); }); }); Q: What is more efficient in python new array creation or in place array manipulation? Say I have an array with a couple hundred elements. I need to iterate of the array and replace one or more items in the array with some other item. Which strategy is more efficient in python in terms of speed (I'm not worried about memory)? For example: I have an array my_array = [1,2,3,4,5,6] I want to replace the first 3 elements with one element with the value 123. Option 1 (inline): my_array = [1,2,3,4,5,6] my_array.remove(0,3) my_array.insert(0,123) Option2 (new array creation): my_array = [1,2,3,4,5,6] my_array = my_array[3:] my_array.insert(0,123) Both of the above will options will give a result of: >>> [123,4,5,6] Any comments would be appreciated. Especially if there is options I have missed. A: If you want to replace an item or a set of items in a list, you should never use your first option. Removing and adding to a list in the middle is slow (reference). Your second option is also fairly inefficient, since you're doing two operations for a single replacement. Instead, just do slice assignment, as eiben's answer instructs. This will be significantly faster and more efficient than either of your methods: >>> my_array = [1,2,3,4,5,6] >>> my_array[:3] = [123] >>> my_array [123, 4, 5, 6] A: arr[0] = x replaces the 0th element with x. You can also replace whole slices. >>> arr = [1, 2, 3, 4, 5, 6] >>> arr[0:3] = [8, 9, 99] >>> arr [8, 9, 99, 4, 5, 6] >>> And generally it's unclear what you're trying to achieve. Please provide more information or an example. OK, as for your update. The remove method doesn't work (remove needs one argument). But the slicing I presented works for your case too: >>> arr [8, 9, 99, 4, 5, 6] >>> arr[0:3] = [4] >>> arr [4, 4, 5, 6] I would guess it's the fastest method, but do try it with timeit. According to my tests it's twice as fast as your "new array" approach. <html><head><meta http-equiv="content-type" content="text/html; charset=utf-8"> <style> .KEYW {color: #933;} .COMM {color: #bbb; font-style: italic;} .NUMB {color: #393;} .STRN {color: #393;} .REGX {color: #339;} .linenumber {border-right: 1px dotted #666; color: #666; font-style: normal;} </style></head><body><pre><span class='linenumber'> 1</span> <span class="COMM">/** <span class='linenumber'> 2</span> * @namespace Stores information about the state of the keyboard <span class='linenumber'> 3</span> */</span><span class="WHIT"> <span class='linenumber'> 4</span> </span><span class="KEYW">var</span><span class="WHIT"> </span><span class="NAME">Keyboard</span><span class="WHIT"> </span><span class="PUNC">=</span><span class="WHIT"> </span><span class="PUNC">{</span><span class="WHIT"> <span class='linenumber'> 5</span> </span><span class="COMM">/** <span class='linenumber'> 6</span> * Hash of keys and whether they are down <span class='linenumber'> 7</span> * @type Hash (String -> Boolean) <span class='linenumber'> 8</span> */</span><span class="WHIT"> <span class='linenumber'> 9</span> </span><span class="NAME">keys</span><span class="PUNC">:</span><span class="WHIT"> </span><span class="KEYW">new</span><span class="WHIT"> </span><span class="NAME">Hash</span><span class="PUNC">(</span><span class="PUNC">)</span><span class="PUNC">,</span><span class="WHIT"> <span class='linenumber'> 10</span> </span><span class="COMM">/** <span class='linenumber'> 11</span> * Whether Cartagen will be controlled by the keyboard <span class='linenumber'> 12</span> * @type Boolean <span class='linenumber'> 13</span> */</span><span class="WHIT"> <span class='linenumber'> 14</span> </span><span class="NAME">key_input</span><span class="PUNC">:</span><span class="WHIT"> </span><span class="KEYW">false</span><span class="PUNC">,</span><span class="WHIT"> <span class='linenumber'> 15</span> </span><span class="PUNC">}</span><span class="WHIT"> <span class='linenumber'> 16</span> </span></pre></body></html>// // Generated by class-dump 3.5 (64 bit) (Debug version compiled Oct 15 2018 10:31:50). // // class-dump is Copyright (C) 1997-1998, 2000-2001, 2004-2015 by Steve Nygard. // #import <AddressBook/NSObject-Protocol.h> @class ABGroupActionScope, ABGroupBrowsingContext, ABGroupDragScope, ABGroupDropScope, ABGroupImportFilesScope, ABGroupSearchingContext, ABSmartGroup, NSString; @protocol ABGroupActionHelper, ABGroupCutHelper, ABGroupDeleteHelper, ABGroupDragHelper, ABGroupDropHelper, ABGroupRenameHelper, ABGroupSelectHelper; @protocol ABGroupHelperFactory <NSObject> - (id <ABGroupActionHelper>)makeImportFilesHelper:(ABGroupImportFilesScope *)arg1 showImportConfirmation:(BOOL)arg2; - (id <ABGroupActionHelper>)makeEditSmartGroupHelper:(ABSmartGroup *)arg1; - (id <ABGroupActionHelper>)makeCreateSmartGroupFromSearchHelper; - (id <ABGroupActionHelper>)makeCreateSmartGroupHelper; - (id <ABGroupSelectHelper>)makeSectionSelectHelperWithIdentifier:(NSString *)arg1; - (id <ABGroupSelectHelper>)makeSearchingSelectHelper:(ABGroupSearchingContext *)arg1; - (id <ABGroupSelectHelper>)makeBrowsingSelectHelper:(ABGroupBrowsingContext *)arg1; - (id <ABGroupDragHelper>)makeDragHelper:(ABGroupDragScope *)arg1; - (id <ABGroupDropHelper>)makeDropHelper:(ABGroupDropScope *)arg1; - (id <ABGroupDeleteHelper>)

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what dying patients teach you. After your death, when most of you for the first time realize what life here is all about, you begin to see that your life here is almost nothing but the sum total of every choice you have made during every moment of your life. Your thoughts, which you are responsible for, are as real as your deeds.You will begin to realize that every word and every deed affects your life and has also touched thousands of lives. I believe that we are solely responsible for our choices, and we have to accept the consequences of every deed, word, and thought throughout our lifetime. There is within each one of us a potential for goodness beyond our imagining; for giving which seeks no reward; for listening without judgment; for loving unconditionally.” Daniel Webster "One may live as a conqueror, a king or a magistrate; but he must die as a man. The bed of death brings every human being to his pure individuality; to the intense contemplation of that deepest and most solemn of all relations, the relation between the creature and his Creator. Here it is that fame and renown cannot assist us; that all external things must fail to aid us; that even friends, affection and human love and devotedness cannot succor us." Dr. Eben Alexander, III on his message from the after-life "You are loved and cherished, dearly, forever. You have nothing to fear. There is nothing you can do wrong over there." George Bernard Shaw "This is the true joy in life - that being used for a purpose recognized by yourself as a mighty one - that being a force of nature instead of a feverish, selfish, little clod of ailments and grievances complaining that the world will not devote itself to making you happy. I am of the opinion that my life belongs to the whole community. As long as I live, it is my privilege to do for it whatever I can. I want to be thoroughly used up when I die, for the harder I work, the morel live. I rejoice in life for its own sake. Life is no brief candle for me. There is a sort of splendid torch which I've got hold of for the moment and I want to make it burn as brightly as possible before handing it on to future generations." "If you wish to upset the law that all crows are black, you must not seek to show that no crows are; it is enough if you can prove one single crow be white." Charles H. Duell, Commissioner U.S. Patent Office 1899 "Everything that can be invented has been invented." Chief Seattle circa 1850: "This we know. All things are connected like the blood which unites one family. All things are connected. Whatever befalls the earth befalls the sons of earth. Man did not weave the web of life; he is merely a strand of it. Whatever he does to the web, he does to himself." Dr. Albert Einstein “You can’t solve a problem using the same level of thinking that got you into that problem”. "Give"Given the millions of billions of Earth-like planets, life elsewhere in the Universe without a doubt, does exist. In the vastness of the Universe we are not alone." "There is not the slightest indication that nuclear energy will ever be obtainable. It would mean the atom would have to be shattered at will." Simon Cameron, U.S. Senator 1901> "I am tired of all this sort of thing called science here ... We have spent millions in that sort of thing for the last few years, and it is time it should be stopped." Wilbur Wright, 1908 "I confess that in 1901 I said to my brother Orville that man would not fly for fifty years. Two years later we ourselves made flights. This demonstration of my impotence as a prophet gave me such a shock that ever since I have distrusted myself and avoided all predictions." Nikola Tesla "Of all the frictional resistance, the one that most retards human movement is ignorance, what Buddha called "the greatest evil in the world." The friction which results from ignorance can be reduced only by the spread of knowledge and the unification of the heterogeneous elements of humanity. No effort could be better spent." "No matter what we attempt to do, no matter to what fields we turn our efforts, we are dependent on power. We have to evolve means of obtaining energy from stores which are forever inexhaustible, to perfect methods which do not imply consumption and waste of any material whatever. If we use fuel to get our power, we are living on our capital and exhausting it rapidly. This method is barbarous and wantonly wasteful and will have to be stopped in the interest of coming generations." Chinese proverb “If we do not change direction, we are likely to end up exactly where we are headed”. Albert A. Michelson German Born American Physicist 1894 "The more important fundamental laws and facts of physical science have all been discovered, and these are now so firmly established that the possibility of their ever being supplanted in consequence of new discoveries is exceedingly remote.... Our future discoveries must be looked for in the sixth place of decimals." Margret Mead “Never doubt the power of a small group of people to change the world. Nothing else ever has”. Buddha “In order to fully understand, you have to be one with what you want to understand”. Paul Davies “You are … host to a billion or so atoms that once belonged to Jesus Christ, or Julius Caesar, or the Buddha, or the tree that the Buddha once sat beneath”. Niccollo Machavelli circa 1500 “There is nothing more difficult to take in hand, more perilous to conduct or more uncertain in its success than to take the lead in the introduction of a new order of things". Dr. Steven Hawking - A Brief History of Time “Ever since the dawn of civilization, people have not been content to see events as unconnected and inexplicable. They have craved an understanding of the underlying order in the world. Today we still yearn to know why we are here and where we came from. Our goal is nothing less than a complete description of the universe we live in.” Dr. Edgar Mitchell on reflections of his trip to the moon: “When I went to the moon, I was as pragmatic a test pilot, engineer, and scientist as any of my colleagues … But there was another aspect to my experience during Apollo 14, and it … began with the breathtaking experience of seeing planet earth floating in the vastness of space. The first thing that came to mind as I looked at earth was its incredible beauty … a splendid blue and white jewel suspended against a velvet black sky. How peacefully, how harmoniously, how marvelously it seemed to fit into the evolutionary pattern by which the universe is maintained. In a peak experience, the presence of divinity became almost palpable and I knew that life in the universe was not just an accident based on random process. … It was knowledge gained through private subjective awareness, but it was - and still is - every bit as real as the objective data upon which, say, the navigational program or the communications system were based. Clearly, the universe had meaning and direction … an unseen dimension behind the visible creation that gives it an intelligent design and that gives life purpose”.module MetaTests exposing (all) import Expect exposing (Expectation) import Form.Error exposing (ErrorValue) import Form.Test.Helpers import Form.Test.ValidationExpectation as ValidationExpectation import Form.Validate as Validate exposing (Validation, string) import Test exposing (..) all : Test all = describe "meta tests" [ test "expect success but get error" <| \() -> let actual = Form.Test.Helpers.getValidationExpectation Validate.email ( "This is definitely not an email address" , ValidationExpectation.Valid ) expected = ValidationExpectation.Invalid Form.Error.InvalidEmail |> Expect.equal ValidationExpectation.Valid in actual |> Expect.equal expected , test "expect success get success" <| \() -> let actual = Form.Test.Helpers.getValidationExpectation Validate.email ( "[email protected]" , ValidationExpectation.Valid ) in actual |> Expect.equal Expect.pass , test "expected error" <| \() -> let actual = Form.Test.Helpers.getValidationExpectation Validate.email ( "This is definitely not an email address" , ValidationExpectation.Invalid Form.Error

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. -4, -2, -1, 6 Sort -1/4, 3/2, 25. -1/4, 3/2, 25 Put 25, -5, -4, -3 in ascending order. -5, -4, -3, 25 Sort -102, 5, 4. -102, 4, 5 Sort 1/4, -2.89, -0.1, 1, 4. -2.89, -0.1, 1/4, 1, 4 Put 1, 10, -11 in descending order. 10, 1, -11 Sort -1/3, 1/4, 18/13, 2 in increasing order. -1/3, 1/4, 18/13, 2 Sort -255, -4, -5 in increasing order. -255, -5, -4 Sort -6, -1, -15 in ascending order. -15, -6, -1 Put 969, 4, 2 in descending order. 969, 4, 2 Put 5, 1/5, 70, 2/7, 1/3 in descending order. 70, 5, 1/3, 2/7, 1/5 Sort -5, 3/5, 50/11 in descending order. 50/11, 3/5, -5 Sort -0.4, -0.2, -0.05, -5 in increasing order. -5, -0.4, -0.2, -0.05 Put -4, 1, 19 in decreasing order. 19, 1, -4 Put -1, -33, -5, -4 in increasing order. -33, -5, -4, -1 Sort -5, -3, 1, 6. -5, -3, 1, 6 Put -1, 18, -0.3, 0 in ascending order. -1, -0.3, 0, 18 Put -276, -1, 3/4, -2 in ascending order. -276, -2, -1, 3/4 Put -684, 1, 0.1 in ascending order. -684, 0.1, 1 Put 3, 4, -0.9, 0.1 in descending order. 4, 3, 0.1, -0.9 Put 4, 3, 28, 5 in decreasing order. 28, 5, 4, 3 Put 20, -4, -5 in decreasing order. 20, -4, -5 Put -9, 3, -4, 0, 15 in ascending order. -9, -4, 0, 3, 15 Put -6, 5/2, 0.05 in descending order. 5/2, 0.05, -6 Sort 2, -97, -9 in increasing order. -97, -9, 2 Sort 2, 1, -1.6. -1.6, 1, 2 Sort 0.22, -4, 2 in decreasing order. 2, 0.22, -4 Sort 4, 641, -5. -5, 4, 641 Put -80, -1, 3 in increasing order. -80, -1, 3 Put -1, -4, 4, 831 in decreasing order. 831, 4, -1, -4 Put -2, -169, 2 in decreasing order. 2, -2, -169 Sort -35, 1/2, 7/4. -35, 1/2, 7/4 Put 10, 4, -1/3, 0 in descending order. 10, 4, 0, -1/3 Sort -1, -2, -189, 4, 2 in decreasing order. 4, 2, -1, -2, -189 Put -6, 2, -0.052, 0 in increasing order. -6, -0.052, 0, 2 Sort 268, -2, -3. -3, -2, 268 Sort -1/2, 15047, 3. -1/2, 3, 15047 Sort 5, 4, -12, -6, -4 in decreasing order. 5, 4, -4, -6, -12 Sort -1, 1, -2, 27 in increasing order. -2, -1, 1, 27 Sort 3, -4, 1, 2, 19 in descending order. 19, 3, 2, 1, -4 Sort -5, 0, -0.1, -0.2 in descending order. 0, -0.1, -0.2, -5 Sort -0.4, -5, 0.4, -0.5 in increasing order. -5, -0.5, -0.4, 0.4 Put -90, 24, 1 in descending order. 24, 1, -90 Sort 7, 1, -4 in ascending order. -4, 1, 7 Sort 4, -4, 339 in descending order. 339, 4, -4 Put -4/3, -26, -2/7 in descending order. -2/7, -4/3, -26 Sort -5, -47, -19 in ascending order. -47, -19, -5 Sort -2/3, 9/4, 2, 2/9. -2/3, 2/9, 2, 9/4 Sort 5, -1325, 3. -1325, 3, 5 Sort -3/8, -0.1, 0.9, 0.047 in decreasing order. 0.9, 0.047, -0.1, -3/8 Sort -4, 0, -0.1, 2 in decreasing order. 2, 0, -0.1, -4 Put 7.04, -3/7, -0.5 in decreasing order. 7.04, -3/7, -0.5 Sort 50, -5, 3. -5, 3, 50 Sort 0.2, -0.3, 2/17, -0.4, -3/2 in ascending order. -3/2, -0.4, -0.3, 2/17, 0.2 Put -2, -5, 28 in descending order. 28, -2, -5 Sort 1/47, 3, -1. -1, 1/47, 3 Sort -4, 0.2, -26, -2, 0.1. -26, -4, -2, 0.1, 0.2 Sort 5, -10, 6. -10, 5, 6 Put 0.2, -5/2, 0, -3 in increasing order. -3, -5/2, 0, 0.2 Put 12, -1, 8, 3 in descending order. 12, 8, 3, -1 Put -257, -1/7, -0.4, -2/3 in descending order. -1/7, -0.4, -2/3, -257 Sort -4, -0.2, 0.4, 55 in increasing order. -4, -0.2, 0.4, 55 Sort -3, -169, -1/4 in descending order. -1/4, -3, -169 Sort 4, 0.3, 2/9. 2/9, 0.3, 4 Sort 0.03, 0.4, 14 in increasing order. 0.03, 0.4, 14 Put 4, -1, 3, 16 in descending order. 16, 4, 3, -1 Sort 3/2, 5, 1, -5 in increasing order. -5, 1, 3/2, 5 Sort -0.01, -0.2, 5 in decreasing order. 5, -0.01, -0.2 Put 0.4, -5, -0.2, 20, -2/5 in decreasing order. 20, 0.4, -0.2, -2/5, -5 Sort -0.1, 5, 3/2, -0.5, -3/13. -0.5, -3/13, -0.1, 3/2, 5 Put -1, -62, -5 in ascending order. -62, -5, -1 Sort 160, 5, -2/7 in increasing order. -2/7, 5, 160 Put -2/5, 2/5, -6, -1/4 in descending order. 2/5, -1/4, -2/5, -6 Put -623, 2, 3, 4 in descending order. 4, 3, 2, -623 Put -1, -47, 5, 12 in decreasing order. 12, 5, -1, -47 Sort 2, 3, 12, -2 in ascending order. -2, 2, 3, 12 Put -0.1, -0.01, -0.

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jandro Granados-Villafuerte (Granados) appeals the sentence he received following his guilty plea conviction for being found illegally in the United States after having been previously removed. Granados argues that one criminal history point should not have been assigned to his 2010 Oklahoma open container traffic offense. * Pursuant to 5TH CIR. R. 47.5, the court has determined that this opinion should not be published and is not precedent except under the limited circumstances set forth in 5TH CIR. R. 47.5.4. Case: 12-50566 Document: 00512199258 Page: 2 Date Filed: 04/05/2013 No. 12-50566 The Government argues that appeal of this sentencing issue is moot and, in the alternative, that the criminal history point was properly assigned to Granados’s prior open container traffic offense. Granados has not filed a reply brief and, thus, has not responded to the Government’s mootness argument. The district court sentenced Granados to 15 months of imprisonment with credit for time served in custody since March 24, 2011. This term of imprisonment necessarily expired on or about June 24, 2012. The Department of Homeland Security has confirmed that Granados was removed from the United States on June 30, 2012. For these reasons, Granados’s appeal is moot. See United States v. Rosenbaum-Alanis, 483 F.3d 381, 383 (5th Cir. 2007). Accordingly, the appeal is DISMISSED AS MOOT. 2 Q: Rails 5.2 encrypted credentials not saving When I do bin/rails credentials:edit my editor opens a file like credentials.yml.enc.1234 with default content. After I'm done editing, I hit save, and the console reads New credentials encrypted and saved. After I run bin/rails credentials:edit again, another temp file gets opened (credentials.yml.enc.4321) and the contents are back to default. How can I make the credentials persist? A: If you aren't using vim, you need to add a wait flag to the editor. e.g for atom: EDITOR="atom --wait" credentials:edit I ran into the same thing and found the answer here. A: There is an issue related to this: https://github.com/rails/rails/issues/31286 It's been fixed already in 5.2.0.rc1 A: I had this problem in rails 5.2.0 using textmate as the editor. It turns out the credentials file must be closed after save in order for the changes to persist. /* * Copyright (C) Sony Computer Entertainment America LLC. * All Rights Reserved. */ using System; using System.Collections.Generic; using System.ComponentModel.Composition; using System.Drawing; using System.IO; using System.Linq; using System.Text; using System.Windows.Forms; using System.Xml; using Sce.Atf; using Sce.Atf.Adaptation; using Sce.Atf.Applications; using Sce.Atf.Controls; using Sce.Atf.Controls.PropertyEditing; using Sce.Atf.Dom; using Sce.Sled.Resources; using Sce.Sled.Shared; using Sce.Sled.Shared.Controls; using Sce.Sled.Shared.Document; using Sce.Sled.Shared.Dom; using Sce.Sled.Shared.Plugin; using Sce.Sled.Shared.Services; using Sce.Sled.Shared.Utilities; using Sce.Sled.SyntaxEditor; namespace Sce.Sled { [Export(typeof(IInitializable))] [Export(typeof(ISledDocumentPlugin))] [Export(typeof(ISledFindAndReplaceService))] [Export(typeof(SledFindAndReplaceService))] [PartCreationPolicy(CreationPolicy.Shared)] class SledFindAndReplaceService : IPartImportsSatisfiedNotification, IInitializable, ISledFindAndReplaceService, ISledDocumentPlugin, ICommandClient { [ImportingConstructor] public SledFindAndReplaceService( MainForm mainForm, ICommandService commandService, ISettingsService settingsService, IControlHostService controlHostService) { m_mainForm = mainForm; m_mainForm.Shown += MainFormShown; m_mainForm.FormClosing += MainFormFormClosing; // Register find and replace -> quick find command commandService.RegisterCommand( Command.QuickFind, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceQuickFind, Localization.SledCommandFindReplaceQuickFindComment, Keys.Control | Keys.F, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register find and replace -> find in files command commandService.RegisterCommand( Command.FindInFiles, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceFindInFiles, Localization.SledCommandFindReplaceFindInFilesComment, Keys.Control | Keys.Shift | Keys.F, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register find and replace -> quick replace command commandService.RegisterCommand( Command.QuickReplace, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceQuickReplace, Localization.SledCommandFindReplaceQuickReplaceComment, Keys.Control | Keys.H, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register find and replace -> replace in files command commandService.RegisterCommand( Command.ReplaceInFiles, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceReplaceInFiles, Localization.SledCommandFindReplaceReplaceInFilesComment, Keys.Control | Keys.Shift | Keys.H, Atf.Resources.FindImage, CommandVisibility.Menu, this); // Register F3 to repeat the last search [w/o showing the GUI] commandService.RegisterCommand( Command.RepeatLastSearchWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceRepeatLastSearchWithoutGui, Localization.SledCommandFindReplaceRepeatLastSearchWithoutGuiComment, Keys.F3, null, CommandVisibility.None, this); // Register Ctrl+F3 to search for next occurrence of the current selected text [w/o showing the GUI] commandService.RegisterCommand( Command.FindSelectedTextWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceFindNextInstanceOfSelectedTextWithoutGUI, Localization.SledCommandFindReplaceFindNextInstanceOfSelectedTextWithoutGUIComment, Keys.Control | Keys.F3, null, CommandVisibility.None, this); // Register Shift+F3 to repeat the last search up [w/o showing the GUI] commandService.RegisterCommand( Command.RepeatLastSearchUpWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator + Localization.SledCommandFindReplaceRepeatLastSearchUpWithoutGui, Localization.SledCommandFindReplaceRepeatLastSearchUpWithoutGuiComment, Keys.Shift | Keys.F3, null, CommandVisibility.None, this); // Register Shift+Ctrl+F3 to search for next occurrence up of the current selected text [w/o showing the GUI] commandService.RegisterCommand( Command.FindSelectedTextUpWithoutGui, StandardMenu.Edit, CommandGroup.FindAndReplace, Localization.SledCommandFindReplace + Resources.Resource.MenuSeparator +

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Title: Wireless Transducer Data Capture andRetrieval System for AircraftSerial #08/815,026Filing Date: Mar. 14, 1997Patent #5,943,140Issue Date: Aug. 24, 1999Title: Method and Apparatus for Sending andReceiving Facsimile Transmissions Over a Non-TelephonicTransmission SystemSerial #09/143,232Filing Date: Aug. 28, 1998Title: Multifunctional Remote Control Systemfor Audio Recording, Capture, Transmission andPlayback of Full Motion and Still ImagesSerial #09/257,448Filing Date: Feb. 25, 1999Title: Multi-Casting CommunicationProtocols for Simultaneous Transmission toMultiple StationsSerial #09/257,720Filing Date: Feb. 25, 1999Patent #6,392,692Issue Date: May 21, 2002Title: Network Communication Techniquesfor Security Surveillance and Safety SystemSerial #09/257,765Filing Date: Feb. 25, 1999Patent #6,366,311Issue Date: Apr. 02, 2002Title: Record and Playback System for AircraftSerial #09/257,767Filing Date: Feb. 25, 1999Patent #6,246,320Issue Date: Jun. 12, 2001Title: Ground Link With On-Board SecuritySurveillance System for Aircraft and OtherCommercial VehiclesSerial #09/257/769Filing Date: Feb. 25, 1999Title: Ground Based Security Surveillance Systemfor Aircraft and Other Commercial VehiclesSerial #09/257,802Filing Date: Feb. 25, 1999Patent #6,253,064Issue Date: Jun. 26, 2001Title: Terminal Based Traffic Management andSecurity Surveillance System for Aircraft and OtherCommercial VehiclesSerial #09/593,901Filing Date: Jun. 14, 2000Title: Dual Mode CameraSerial #09/594,041Filing Date: Jun. 14, 2000Title: Multimedia Surveillance and MonitoringSystem Including Network ConfigurationSerial #09/687,713Filing Date: Oct. 13, 2000Title: Apparatus and Method of Collectingand Distributing Event Data to StrategicSecurity Personnel and Response VehiclesSerial #09/966,130Filing Date: Sep. 21, 2001Title: Multimedia Network Appliancesfor Security and Surveillance ApplicationsSerial #09/974,337Filing Date: Oct. 10, 2001Title: Networked Personal Security SystemSerial #09/715,783Filing Date: Nov. 17, 2000Title: Multiple Video Display Configurationsand Bandwidth Conservation Scheme forTransmitting Video Over a NetworkSerial #09/716,141Filing Date: Nov. 17, 2000Title: Method and Apparatus forDistributing Digitized Streaming Video Over aNetworkSerial #09/725,368Filing Date: Nov. 29, 2000Title: Multiple Video Display Configurationsand Remote Control of Multiple Video SignalsTransmitted to a Monitoring Station Over a NetworkSerial #09/853,274Filing Date: May 11, 2001Title: Method and Apparatus for Collecting,Sending, Archiving and Retrieving Motion Video andStill Images and Notification of Detected EventsSerial #09/854,033Filing Date: May 11, 2001Title: Portable, Wireless Monitoring andControl Station for Use in Connection With aMulti-Media Surveillance System Having EnhancedNotification FunctionsSerial #09/866,984Filing Date: May 29, 2001Title: Modular Sensor ArraySerial #09/960,126Filing Date: Sep. 21, 2001Title: Method and Apparatus for InterconnectivityBetween Legacy Security Systems and Networked MultimediaSecurity Surveillance SystemSerial #10/134,413Filing Date: Apr. 29, 2002Title: Method for Accessing and Controlling aRemote Camera in a Networked System With MultipleUser Support Capability and Integration to OtherSensor Systems Several companies have developed computer algorithms that are capable of producing a “digital signature” from video images of people's faces. These signatures are much like a fingerprint: they are unique to individuals; they are relatively small so they are efficient; and, they may be used in databases to look up the identity and other data about the person. While other types of biometrics, such as iris scanning, are at best or even more accurate than facial recognition (which has a relatively low error rate; just under 1 percent), facial recognition will probably be accepted more widely because it is not intrusive. Further, it does not require that the user push, insert or click on anything. Companies often do not need to install anything beyond the new software because most already have cameras in place and pictures of employees on file—making it less expensive than iris reading setups. In addition, the relatively small size of the database for a facial profile makes it an attractive technology. One example of a currently available facial recognition software is the Visionics' FaceIt system. The FaceIt software measures a face according to its peaks and valleys—such as the tip of the nose, the depth of the eye sockets—which are known as nodal points. A typical human face has 80 nodal points and precise recognition can be achieved with as few as 14 to 22 utilizing the FaceIt system. Specifically, the FaceIt system concentrates on the inner region of the face, which runs from temple to temple and just over the lip, called the ‘golden triangle.’ This is the most stable because even if facial hair such as a beard is altered, or if the subject changes or adds glasses, changes in weight or ages substantially the ‘golden triangle’ region tends to not be affected, while places such as under chin would be substantially altered. FaceIt plots the relative positions of these points and comes up with a long string of numbers, called a faceprint. Visage Technology of Littleton, Mass., has a slightly different model. Its software compares faces to 128 archetypes it has on record. Faces are then assigned numbers according to how they are similar or different from these models. The Visage Technology has been utilized to date in the identification of criminals, for access control, for transaction security and for identity fraud prevention. Most recently, government and aviation officials are poised to begin using facial recognition systems to scan airport terminals for suspected terrorists. Recently, Visionics has teamed up with a domestic airline to demonstrate a conceptual boarding system that will use FaceIt to facilitate the rapid boarding of the airline's frequent flyers. In the past, law enforcement officials often have no more than a facial image to link a suspect to a particular crime or previous event. Up to now, database searches were limited to textual entries (i.e., name, social security number, birth date, etc.), leaving room for error and oversight. By conducting searches against facial images, the facial recognition technology permits rapid review of information and quickly generated results, with the ability to check literally millions of records for possible matches, and then automatically and reliably verifying the identity of a suspect. The facial recognition technology has several advantages over other biometric systems. For example, with facial recognition technology a person can be identified at a distance or in a crowd. The technology has the capability of capturing a face in the field of view, extract the face from the background data and compare it against a database. The system permits the creation of watch lists or the like. This could include, for example, known shoplifters, terrorists or criminals, as well as frequent customers, VIP's, expected visitors or individuals generally classified as friends or foes. The system can be used at airports, casinos, public buildings, schools, subways, colleges, factories, business facilities, housing complexes, residences and the like. The system also is useful in transaction modes. Customers are used to being verified or being recognized by their face at retail locations by providing merchants with a driver's license or other form of photo ID. In sharp contrast to today's widely used signature verification process, which is highly unreliable and cannot be accurately determined by unskilled and untrained clerks, face recognition makes verification reliable, automatic and fast. In banking, facial recognition technology can adapt to already installed ATM cameras for recognizing and verifying customer identities so the financial transaction can be quickly and effortlessly conducted. Such technology can replace reliance on alphanumeric PINs to identify and authenticate a user. Face recognition is the only biometric that can be used in two modalities—logon and continuous monitoring. An example of logon modality is use as a perimeter defense mechanism, where an authorized individual gains entry to a network or session after a one-time logon process. This is the typical mode for all biometric systems. In addition, face recognition supports a continuous monitoring mode where persons are continuously authenticated for ensuring that at all times the individual in front of the computer or handheld device continues to be the same authorized person who logged in. Currently available technology focuses on the following aspects of facial recognition: Detection—When the system is attached to a video surveillance system, the recognition software searches the field of view of a video camera for faces. If there is a face in the view, it is detected within a fraction of a second. A multi-scale algorithm is used to search for faces in low resolution. The system switches to a high-resolution search only after a head-like shape is detected. Alignment—Once a face is detected, the system determines the head's position, size and pose to assure that the face is appropriately turned toward the camera for the system to register it. Normalization—The image of the head is scaled and rotated so that it can be registered and mapped into an appropriate size and pose. Normalization is performed regardless of the head's location and distance from the camera. Representation—The system translates the facial data into a unique code. This coding process

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1]). Vascular endothelial growth factor (VEGF)-A has been identified as the predominant tumor angiogenesis factor in the majority of human and experimental murine cancers ([@bib2]), acting via VEGF receptor (VEGFR)-1 and VEGFR-2. Recent studies in mouse tumor models, however, have suggested that some types of malignant tumors also induce the formation of lymphatic vessels (lymphangiogenesis), and that this process promotes tumor spread to regional lymph nodes ([@bib3]--[@bib5]). Moreover, tumor lymphangiogenesis has been identified as a novel prognostic factor for determining the risk for human cutaneous melanomas to become metastatic ([@bib6]). In contrast to the detailed characterization of the molecular mechanisms that control (blood vascular) angiogenesis, the mechanisms underlying the pathologic growth and function of the lymphatic vascular system have remained poorly understood. Thus far, VEGF-C and VEGF-D are the only known lymphangiogenesis factors---acting predominantly through activation of VEGFR-3---which is expressed by lymphatic endothelium in vivo and in vitro ([@bib7]). Several studies in animal tumor models have provided direct experimental evidence that increased levels of VEGF-C or VEGF-D promote tumor lymphangiogenesis and tumor spread via the lymphatic vessels to regional lymph nodes. Furthermore, these effects can be suppressed by blocking VEGFR-3 signaling ([@bib3]--[@bib5], [@bib8]--[@bib10]). Other factors, however, are likely to be involved in mediating tumor lymphangiogenesis and metastasis to the lymph nodes ([@bib11]). Generally, VEGF-A has been considered to only promote (blood vascular) angiogenesis; however, recent work from several laboratories revealed that VEGF-A promotes human lymphatic endothelial cell proliferation and migration in vitro ([@bib12]--[@bib15]), and that lymphatic endothelium expresses VEGFR-2 in situ and in vitro ([@bib12], [@bib13], [@bib16]--[@bib18]). Moreover, intradermal injection of mice with an adenoviral vector engineered to express mouse VEGF-A, but not with adenoviral human VEGF-A ([@bib18]), resulted in the production of enlarged, proliferating lymphatic vessels ([@bib16]). Our recent work has shown that chronic transgenic delivery of VEGF-A to mouse skin promoted lymphangiogenesis associated with chronic skin inflammation ([@bib19]) and with cutaneous tissue repair ([@bib13]). To investigate whether VEGF-A also might be involved in mediating tumor lymphangiogenesis and metastasis to the lymph node, we generated a new transgenic mouse model to target expression of GFP to normal and malignant epidermal keratinocytes. GFP expression was controlled by a keratin 14 (K14) promoter-driven transgene cassette. This model enables the sensitive detection and quantification of lymph node metastasis during experimental, multi-step skin carcinogenesis. We then crossed these mice with our previously established K14/VEGF-A transgenic mice ([@bib20], [@bib21]), and subjected the offspring, which produce fluorescent keratinocytes in the skin that also overexpress VEGF-A, to a chemically induced, multi-step skin carcinogenesis regimen ([@bib22], [@bib23]). We found that targeted overexpression of VEGF-A potently induced tumor lymphangiogenesis in cutaneous squamous cell carcinoma (SCC) and promoted tumor metastasis to sentinel lymph nodes. Importantly, VEGF-A--expressing tumor cells maintained their lymphangiogenic activity after metastasis to lymph nodes. Surprisingly, VEGF-A--overexpressing cutaneous SCC induced lymphangiogenesis in sentinel lymph nodes, even before the tumors had metastasized to these tissues. Together, these results identify VEGF-A as a novel tumor lymphangiogenesis factor. They also indicate that VEGF-A--induced lymph node lymphangiogenesis promotes metastasis, and therefore, is an important target for the treatment of advanced cancer and the prevention of metastasis. RESULTS ======= Transgenic expression of GFP in the skin enables detection and quantification of SCC metastasis to lymph nodes -------------------------------------------------------------------------------------------------------------- To facilitate detection and quantification of skin cancer metastases, we created a transgenic mouse model to selectively express GFP in epidermal keratinocytes, using a K14 promoter cassette ([Fig. 1](#fig1){ref-type="fig"} A). Three transgenic founder lines expressed high levels of GFP in the skin; targeted expression of the K14/GFP transgene in the basal epidermal keratinocyte layer and in outer root sheath keratinocytes of hair follicles was confirmed by fluorescence microscopy ([Fig. 1](#fig1){ref-type="fig"} B). Induction of epidermal hyperplasia by topical application of PMA to the ear skin of transgenic mice resulted in strong GFP expression throughout the hyperplastic epidermis at 1 and 4 d afterward ([Fig. 1](#fig1){ref-type="fig"} C, D). ![K14/GFP transgenic mice provide a reliable new model for the detection of skin cancer metastases. (A) Schematic representation of the K14-GFP transgenic construct. A 720-bp enhanced GFP (EGFP) cDNA fragment was ligated to the BamHI restriction site of the keratin 14 promoter cassette. (B) Targeted expression of the K14/GFP transgene in the basal epidermal keratinocyte layer and in outer root sheath keratinocytes of hair follicles was confirmed by fluorescence microscopy (green). (C and D) Induction of epidermal hyperplasia by topical application of PMA resulted in strong GFP expression throughout the epidermis. Nuclei are labeled blue (Hoechst stain). (E and F) High levels of GFP expression (green) were maintained in tumor cells of papillomas (E) and of SCC (F) induced by the chemical skin carcinogenesis regimen. Immunostains for the panvascular marker CD31 (E; red) revealed tumor-associated angiogenesis, whereas immunostains for the lymphatic-specific marker LYVE-1 (F; red; arrowheads) demonstrated lymphangiogenesis in close association with tumor cells at the advancing tumor edge. (G and H) Metastatic tumor cells in sentinel lymph nodes of K14/GFP transgenic mice maintained high levels of GFP expression, enabling simple detection of lymph node metastasis by fluorescence microscopy (G, green) and quantification of GFP-positive and CD45-negative metastatic tumor cells (66.2% of all cells in this representative case) by FACS analysis of single cell suspensions (H). Bars, 100 μm (B--F), 500 μm (G).](20041896f1){#fig1} To investigate whether GFP expression also was maintained during the successive stages of multi-step skin carcinogenesis and metastasis, the K14/GFP transgenic line that expressed the highest level of GFP was subjected to a standard 7,12-dimethylbenzanthracene (DMBA)/PMA chemical skin carcinogenesis regimen. This involved a single dose of DMBA to initiate tumor formation, followed by 20 weekly applications of the tumor promoter PMA. High levels of GFP expression were detected in all of the cells of early benign papillomas that already displayed marked tumor angiogenesis, as detected by stains for the vascular marker CD31, adjacent to the GFP-expressing tumor cells ([Fig. 1](#fig1){ref-type="fig"} E). Similarly, SCC cells maintained strong GFP expression, and immunostains for the lymphatic-specific marker lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) demonstrated lymphangiogenesis in close association with tumor cells at the advancing tumor edge ([Fig. 1](#fig1){ref-type="fig"} F). Importantly, metastatic tumor cells in sentinel lymph nodes of K14/GFP transgenic mice also maintained strong GFP expression, enabling the simple detection of metastasis to the lymph node by fluorescence microscopy ([Fig. 1](#fig1){ref-type="fig"} G). We investigated whether the extent of metastasis to the lymph node might be quantified by flow cytometry analysis of homogenized lymph nodes. GFP-positive/CD45-negative tumor cells were easily detectable and represented up to ∼66.2% of all sorted lymph node cells ([Fig. 1](#fig1){ref-type="fig"} H). Together, these results established the K14/GFP transgenic model as a suitable model for comparative studies of skin cancer metastasis. Accelerated and increased skin carcinogenesis in VEGF-A transgenic mice ----------------------------------------------------------------------- To investigate the effects of VEGF-A on tumor progression and metastasis, we crossed our line of K14/GFP mice that expressed the highest level of GFP with previously established and characterized heterozygous K14/VEGF-A transgenic mice ([@bib20]). This led to the establishment of K14/GFP and K14/GFP/VEGF-A transgenic mice. These mice were then subjected to the skin carcinogenesis regimen described above. VEGF-A transgenic mice showed accelerated formation of skin papillomas, with an average latency period of 6 wk after the first PMA application, as compared with 12 wk for wild-type mice ([Fig. 2](#fig2){ref-type="fig"} A). By 7 wk, 100% of VEGF-A transgenic mice had developed papillomas, whereas none of the wild-type mice had developed any visible tumor at this time point ([Fig. 2](#fig2){ref-type="fig"} A). The number of papillomas also was increased dramatically in VEGF-A transgenic mice. After 20 wk of PMA treatment, VEGF-A overexpression resulted in the formation of more than 40 papillomas per mouse, as compared with less than 7 papillomas that formed, on the average, in wild-type mice (P \< 0.001; [Fig. 2](#fig2){ref-type="fig"} B). ![Accelerated and increased skin carcinogenesis in VEGF-A transgenic mice. (A) Accelerated development of skin papillomas in VEGF-A transgenic mice (n = 34; filled squares), as compared with wild-type mice (n = 31; open circles). Incidence is expressed as the percentage of mice with detectable papillomas (\>1 mm) during the 20 wk of topical PMA application. (B) Significant increase in frequency of papilloma formation in VEGF-A transgenic mice, expressed as the average number of papillomas per mouse

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town of Fuquay-Varina and portions of the town of Holly Springs. References Category:Townships in Wake County, North Carolina Category:Townships in North CarolinaWhy are some prison sentences so long? Magazine Monitor A collection of cultural artefacts Published duration 1 August 2013 image caption After sentencing, the judge told Ariel Castro he was too dangerous to ever be released Kidnapper and rapist Ariel Castro has been sentenced to life without parole plus 1,000 years. What's the point in extending a prison term beyond a person's lifetime, asks Tom Geoghegan. Sentencing is not just about determining how long someone should be behind bars, it also has a symbolic, theatrical function, says Franklin Zimring, a professor of law at the University of California, who has written extensively about deterrents. "In sentencing Bernie Madoff [to 150 years for fraud], what the judge wants to be telling him is 'you are really a bad person.' And for this purpose, the number of years can be endlessly elastic." How much symbolic denunciation plays a part can depend on many things, such as media coverage or the nature of an offence, but the tension between these two radically different functions - the symbolic and practical - is a feature of modern criminal justice systems, he says, and not just in the US. There was a famous case in Spain where a fraudster received a 2,000-year sentence. Parole means the sentence can be adjusted at a later date. But it has been eliminated for life sentences in many parts of the country. Most criminal prosecutions in the US are brought by the state, so there can be huge variations in sentencing. Judges are constrained by a statutory range but, depending on the crime, that could be very broad or have no maximum sentence at all. Fraud against one person can involve multiple crimes like false statements, wire fraud and theft, so consecutive sentences for each charge can fast add up. The same goes for crimes involving a computer, like child pornography, because each image could be a separate count. Minor misdemeanours are more likely to result in concurrent sentences. For victims of crime and their loved ones there is nothing problematic about a very long sentence. Indeed, a sentence that increases with each guilty charge is a way of telling each victim that they matter. Some long sentences are an alternative to the death penalty. Dudley Wayne Kyzer is serving two life terms plus 10,000 years for a triple murder he committed in the 1970s. After four years on death row, he was given a second trial because the death penalty in Alabama was at the time deemed unconstitutional.Q: Material UI Box Border for float-right bootstrap element Using a Material UI Box to show border which consist of a bootstrap element <input type="submit" className="btn btn-primary float-right" value="Send" /> Here is the code sandbox link https://codesandbox.io/s/compassionate-forest-81kn0?file=/src/App.js:490-501 The Send Button appears outside the Box when float-right is used. Send Button appears inside the Box when float-right is removed. How to make it float to right while also making it within the Material UI Box. A: Ciao, you could use style to make this. In your input define a style like: <input style={styles.input} type="submit" className="btn btn-primary" value="Send" /> Then in style set display: "flex" and marginLeft: "auto" in this way: const styles = { input: { display: "flex", marginLeft: "auto" } }; and button will appears in form, floated on right. Here your codesandbox modified. Biomechanical studies of the anterior spinal fixators after corpectomy in pigs. An unstable corpectomy porcine spinal model was created for the testing of anterior spinal fixators including: Kaneda device (KD), combination of Polster-Brinckmann prosthesis and Zielke implant (PBZ), and a new prototype device (CH). These spinal implants were examined in a one above/one below corpectomy model to determine the relative stiffness of each construct and the deformation of the adjacent discs under loading. The results indicated that the relative torsion and flexion stiffness were higher for the tested spines fixed with KD and CH. However, the relative compression stiffness of the tested spines was the same for all devices. The rigidity of the spinal constructs, which were measured around the corpectomy region showed the same tendency as above. However, the stiffness of CH and KD constructs were significantly higher than that of the PBZ construct under flexion and torsion. The difference in deformation of the upper and lower adjacent discs was not obvious among the intact spine and the spinal constructs with different devices. Clinical relevances: The corpectomy model represents a "worst case" scenario of spinal instability. In many conditions, spinal reconstructive surgery can restore axial compressive, torsional, and flexural rigidity to normal levels. These experimental conclusions apply to acute restoration of stability, rather than to rigidity after long-term cyclical loading. These three anterior fixators extended to only one cephalad level and one caudal level beyond the corpectomy defect. The new prototype device (CH) has a stability to the Kaneda device. The superior mechanical strength and simpler operative procedure of the new device provide for a potential clinical advantage in restoration of unstable spinal conditions.2012 IRB Junior World Championship squads The 2012 IRB Junior World Championship was an international rugby union tournament held in South Africa from 4 June until 22 June. The tournament was open to players who were born in or after 1992. This article lists the official squads for the 2012 IRB Junior World Championship in South Africa. Pool A Fiji Fiji's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Sale Sorovaki New Zealand New Zealand's 29-man squad for the 2012 IRB Junior World Championship. Head Coach: Rob Penney Samoa Samoa's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: John Schuster Wales Wales's 30-man squad for the 2012 IRB Junior World Championship. Head Coach: Danny Wilson Pool B England England's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Rob Hunter Ireland Ireland's 29-man squad for the 2012 IRB Junior World Championship. Head Coach: Mike Ruddock Italy Italy's 30-man squad for the 2012 IRB Junior World Championship. Head Coach: Craig Green South Africa South Africa's 31-man squad for the 2012 IRB Junior World Championship. Head Coach: Dawie Theron Pool C Argentina Argentina's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Facundo Soler, Bernardo Urdaneta Velez Australia Australia's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: David Nucifora France France's 31-man squad for the 2012 IRB Junior World Championship. Head Coach: Didier Retiere Scotland Scotland's 28-man squad for the 2012 IRB Junior World Championship. Head Coach: Peter Wright References External links 2012Q: Is it a bad idea to put the logo in the top-right corner and the navigation in the top-left? Firstly I would like to say that I don't think there is a concrete rule about where the logo on a website should be – but intuitively I think it should be in the top left at least for continuities sake. Is it bad UX to have the navigation placed before a company logo and why? A: This article might also help: Jakob Nielsen: Horizontal Attention Leans Left Extract: People spent more than twice as much time looking at the left side of the page as they did the right: Left half of screen: 69% of viewing time Right half of screen: 30% of viewing time Simply put: Stick to the conventional layout, because it works perfectly with how people look at Web pages: Keep navigation all the way to the left. This is where people look to find a list of current options. Keep the main content a bit further in from the left. The most important stuff should be showcased between one-third and halfway across the page. This is where users focus their attention the most. Keep secondary content to the right. It won't be seen as much here, but that's okay — not everything can get top billing, and you need a place to put less-important material. A: You have to decide what is more important for a company and then what is more representative for that company's website: the logo or the navigation. The positioning of the logo in the top left corner is not a rule set in stone, it's a result of the research that tells us that the eye movement on a website usually starts from the left side. You need to read more on eye movement patters, especially about the F-pattern which is relevant in this case. The bottom line is that if you

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are due. It's a small entertainment, but at least it's working. You have solar? Not hooked up to the zero point? Very long-sighted of you. Now: watch! Varaha, Vamana, Buddha and Kalki! They flow from their painted stools like liquid and run around the inside of the ring, an effortless, cat-lazy lope. The trick with cat circuses, I have found, is to convince them they are doing it for themselves. And lo! I clap my hands and in perfect unison my cats leap from their ordained orbits clean through the paper hoops. Your applause please, but not for me: for Varaha, Vamana, Buddha and Kalki. Now they run in a circle, hurdling through the hoops. What was that? Is there a lesson in every trick? What do you mean? The spiritual significance of the cats I call to perform? I hadn't thought of that. I don't think cats especially spiritual; quite the reverse; they are the most worldly and sensual of creatures, though the Prophet Mohammed, so it's said, was a great lover of cats and famously cut the sleeve from his robe rather than disturb a cat that had fallen asleep there. Now, on with the story. Where am I going? Don't you know it's a terrible rudeness to interrupt the storyteller? You came here to see the cat circus, not watch some old goondah spin a yarn? You've seen cats leap through paper hoops, what more do you want? Where am I going? Very well then, to Varanasi. No, I am not. It's not just the bodhisofts who go to Varanasi. Here's the deal. I have plenty more tricks in my little ring here on the sand, but to see them you will have to listen to my story and remember, the power may be working but the broadcasters are out. Nothing on your screens tonight. But you'll like this. It's a wedding scene. What is a story without a wedding? Elephants bore me. When I say that I don't mean that I find the pachyderm genus tedious, as if I have some special personal conversational relationship with them and knew all their conversational tics and ploys. Is Ganesh not the best-loved god in our entire profligate pantheon? I mean, simply, that elephants carried me; in a howdah like a small gilt temple through the streets of Delhi. Five elephants, with mahouts; one for my school friend Suresh Hira, one for Vin Johar, one for Syaman and one, my sole spit of defiance in the face of tradition, for Sarasvati, and one for me, Vishnu Nariman Raj, the gnarly groom. Delhi's eternal, monstrous traffic broke around the horde of musicians, drummers, dancers, merry-meeters like water. The traffic news had been reporting me as a major congestion for hours. People stopped and stared, women threw rice, ayahs pointed me out to their finger-sucking grandchildren: _there, there he is, Lord Vishnu goes to his wedding._ The chati mags had been full of little else than the first dynastic Brahmin marriage. My other break with tradition: much of the gaudy I had funded myself through the judicious auctioning of the photo rights to _Gupshup_ magazine. Look here am I, in white sherwani and wrinkle-ankle pants in the very best style, the traditional veil of flowers over my face, gripping my sword with one hand (a ludicrous affectation by Sreem, Delhi's most-sought nute wedding choreographer; who could ever sword-fight from the broad back of an elephant?), with the other gripping white-knuckled to the gold-leaf coping of my swaying howdah. Have I said that riding an elephant is like being on a boat on unstill waters? Does what you glimpse through the cascading marigolds look afraid? Were you expecting someone larger? Negotiations had been protracted and delicate over the winter. Hosts of aeai attorneys circled and clashed around my mother and father, temporarily unified, as they entertained the Misras to a grand vagdana. Lakshmi and I sat blandly, quietly, hands folded neatly in our laps on the cream leather sofa as relatives and relatives passed and greeted and blessed us. We smiled. We nodded. We did not speak, not to our guests, not to each other. In our years together at the Dr Renganathan Brahminical College we had said all that we could say to each other. We sat like an old married couple at a metro stop. At last the hosts of clashing attorney aeais withdrew: a pre-nuptial contract was drafted, a dowry was set. It was a brilliant match; property and ware with water, the very essence of life. Of course the price was high; we were Brahmins. It was no less than the flesh of our flesh and the seed of our loins, for all generations. Way down the list of ticky boxes on Dr Rao's shopping list was one I suspect Lakshmi's parents had tickied blindly. I know my parents had. But it was perhaps the most profound change of all that Dr Rao's nanoworkers worked on us. Our genelines were modified. The traits engineered into us were inheritable. Our children and their children, all our conceivable Nariman-Misras marching into futurity, would be Brahmins, not from the microsurgery of Dr Rao, but from our sperm and eggs. Children, offspring, a line, a dynasty. That was our mutually contracted dowry. A match was made! Let great Delhi rejoice! The janampatri aeais had read the stars for the most auspicious fates, the pandit had made the puja to Ganesh and the joint houses of Nariman and Misra had hired _Gupshup Girls_ , Delhi's biggest and brassiest girl band to sing and flash their thighs for two thousand society guests at our sangeet sandhya. Lakshmi duetted onstage with them. Pop-girli hotpants and belly-top looked disturbing on her as she danced and skipped among the high-heels. Too small, too too young to wed. I was never much of a singer. Mamji and Dadaji had neglected to ticky that box. I boogied down in the golden circle with my classmates. Though I had still two years more at Dr Renganathan College under the tutelage of the invisible Mr Khan, our circle was broken. I was all their imminent futures. At India Gate Sarasvati called her mahout to a halt and slipped from her elephant's back to run and dance among my parade of Baraatis. I had defied tradition by inviting her, she defied it back by coming dressed as a man in sherwani and kohl and huge, ludicrous false Rajput moustache. I watched her leap and whirl, brilliant and vivacious with the dancers and drummers and dance, laughing, with monkey-like Sreem and felt tears in my eyes behind my veil of flowers. She was so brilliant, so lovely, so lithe and free from expectation. At Lodi Gardens the celebrity spotters were five deep. Policemen held them back with a chain of linked lathis. They had seen Rishi Jaitly and Anand Arora and ooh, isn't that Esha Rashore the famous dancer and who is that little man with the very much younger wife; don't you know, it's Narayan Mittal from Mittal Industries. Last and least to them was the seeming child perched high on the back of a painted wedding elephant. A blare of trumpets and a barrage of drums greeted us. Then the smartsilk screens draped around us woke up and filled with the characters and, in a never-before-seen-feat of CG prestidigitation, the cast of _Town and Country_ singing and dancing our wedding song specially written by legendary screen composer A.H. Husayin. They were aeais; singing and dancing were easy for them. There, almost lost among the sari silk and garlands as the bridal party stepped forward to greet us, was Lakshmi. We were swept on a wave of drum beating and brass-tootling to the pavilions arrayed across the well-watered grass like a Mughal invasion. We feasted, we danced, we were sat on our thrones, our feet not touching the ground, and received our guests. I didn't see him. The line was long and the atmosphere in marquee stifling and I was bloated and drowsy from wedding food. I took the hand blindly, bored. I only became attentive when it held mine that moment too long, that quantum too firmly. Shiv. "Brother." I nodded in acknowledgment. "Are you well?" He indicated his suit, the fabric cheap, the cut niggardly, the cufflinks and the jewel at the shirt-throat phoney. A bud get wedding outfit. Tomorrow it would go by phatphat back to the hire shop. "I'll be more suitably dressed when you come to my wedding." "Are you getting married?" "Doesn't everyone?" I

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ArenaNoVirtual() != NULL); if (type_name != NULL) { } else { } type_name_.UnsafeArenaSetAllocated(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), type_name, GetArenaNoVirtual()); // @@protoc_insertion_point(field_unsafe_arena_set_allocated:tensorflow.VariantTensorDataProto.type_name) } // bytes metadata = 2; inline void VariantTensorDataProto::clear_metadata() { metadata_.ClearToEmpty(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline const ::std::string& VariantTensorDataProto::metadata() const { // @@protoc_insertion_point(field_get:tensorflow.VariantTensorDataProto.metadata) return metadata_.Get(); } inline void VariantTensorDataProto::set_metadata(const ::std::string& value) { metadata_.Set(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), value, GetArenaNoVirtual()); // @@protoc_insertion_point(field_set:tensorflow.VariantTensorDataProto.metadata) } #if LANG_CXX11 inline void VariantTensorDataProto::set_metadata(::std::string&& value) { metadata_.Set( &::google::protobuf::internal::GetEmptyStringAlreadyInited(), ::std::move(value), GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_rvalue:tensorflow.VariantTensorDataProto.metadata) } #endif inline void VariantTensorDataProto::set_metadata(const char* value) { GOOGLE_DCHECK(value != NULL); metadata_.Set(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), ::std::string(value), GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_char:tensorflow.VariantTensorDataProto.metadata) } inline void VariantTensorDataProto::set_metadata(const void* value, size_t size) { metadata_.Set(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), ::std::string( reinterpret_cast<const char*>(value), size), GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_pointer:tensorflow.VariantTensorDataProto.metadata) } inline ::std::string* VariantTensorDataProto::mutable_metadata() { // @@protoc_insertion_point(field_mutable:tensorflow.VariantTensorDataProto.metadata) return metadata_.Mutable(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline ::std::string* VariantTensorDataProto::release_metadata() { // @@protoc_insertion_point(field_release:tensorflow.VariantTensorDataProto.metadata) return metadata_.Release(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline ::std::string* VariantTensorDataProto::unsafe_arena_release_metadata() { // @@protoc_insertion_point(field_unsafe_arena_release:tensorflow.VariantTensorDataProto.metadata) GOOGLE_DCHECK(GetArenaNoVirtual() != NULL); return metadata_.UnsafeArenaRelease(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), GetArenaNoVirtual()); } inline void VariantTensorDataProto::set_allocated_metadata(::std::string* metadata) { if (metadata != NULL) { } else { } metadata_.SetAllocated(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), metadata, GetArenaNoVirtual()); // @@protoc_insertion_point(field_set_allocated:tensorflow.VariantTensorDataProto.metadata) } inline void VariantTensorDataProto::unsafe_arena_set_allocated_metadata( ::std::string* metadata) { GOOGLE_DCHECK(GetArenaNoVirtual() != NULL); if (metadata != NULL) { } else { } metadata_.UnsafeArenaSetAllocated(&::google::protobuf::internal::GetEmptyStringAlreadyInited(), metadata, GetArenaNoVirtual()); // @@protoc_insertion_point(field_unsafe_arena_set_allocated:tensorflow.VariantTensorDataProto.metadata) } // repeated .tensorflow.TensorProto tensors = 3; inline int VariantTensorDataProto::tensors_size() const { return tensors_.size(); } inline void VariantTensorDataProto::clear_tensors() { tensors_.Clear(); } inline const ::tensorflow::TensorProto& VariantTensorDataProto::tensors(int index) const { // @@protoc_insertion_point(field_get:tensorflow.VariantTensorDataProto.tensors) return tensors_.Get(index); } inline ::tensorflow::TensorProto* VariantTensorDataProto::mutable_tensors(int index) { // @@protoc_insertion_point(field_mutable:tensorflow.VariantTensorDataProto.tensors) return tensors_.Mutable(index); } inline ::tensorflow::TensorProto* VariantTensorDataProto::add_tensors() { // @@protoc_insertion_point(field_add:tensorflow.VariantTensorDataProto.tensors) return tensors_.Add(); } inline ::google::protobuf::RepeatedPtrField< ::tensorflow::TensorProto >* VariantTensorDataProto::mutable_tensors() { // @@protoc_insertion_point(field_mutable_list:tensorflow.VariantTensorDataProto.tensors) return &tensors_; } inline const ::google::protobuf::RepeatedPtrField< ::tensorflow::TensorProto >& VariantTensorDataProto::tensors() const { // @@protoc_insertion_point(field_list:tensorflow.VariantTensorDataProto.tensors) return tensors_; } #ifdef __GNUC__ #pragma GCC diagnostic pop #endif // __GNUC__ #endif // !PROTOBUF_INLINE_NOT_IN_HEADERS // ------------------------------------------------------------------- // @@protoc_insertion_point(namespace_scope) } // namespace tensorflow // @@protoc_insertion_point(global_scope) #endif // PROTOBUF_tensorflow_2fcore_2fframework_2ftensor_2eproto__INCLUDED 1. Introduction {#sec1-ijms-20-04632} =============== The results of decades-long research have shown that the therapeutic use of stem cells brings about significant improvements, even in cases of diseases incurable by other methods. Stem cell research is developing very dynamically. Their regenerative potential is used in medicine. Currently, the wide use of stem cells in therapies of many diseases is awaited with high hopes. Wharton's Jelly is a specialized type of connective tissue located inside the umbilical cord, from which mesenchymal stem cells (WJ-MSCs) can be isolated. WJ-MSCs express all surface markers typical for mesenchymal stem cells \[[@B1-ijms-20-04632]\]. These cells, properly cultured and stimulated, are capable of differentiating towards other types of cells \[[@B2-ijms-20-04632]\]. The publications appearing in recent years show the huge plasticity of WJ-MSCs, which have the ability to differentiate not only towards mesodermal cells, such as cardiomyocytes, but also into cells of ectodermal (neurons) and endodermal (hepatocytes) origin \[[@B3-ijms-20-04632],[@B4-ijms-20-04632]\]. In addition, unlike ESC (Emrbyonic Stem Cells), they do not create ethical problems in scientific research. They have higher proliferation and self-renewal rate compared to somatic stem cells \[[@B4-ijms-20-04632]\]. Wharton's Jelly is an extremely valuable source of stem cells. It has been calculated that up to 4 × 10^5^ stem cells can be isolated from a 15 cm long umbilical cord fragment. WJ-MSCs are also characterized by high subdivision activity. They are well tolerated by the immune system, which favors the possibilities for their use in medicine, both in auto and allogeneic transplants \[[@B5-ijms-20-04632]\]. Chronic ischemia of the lower limbs is a condition in which blood flow through the arteries supplying blood to the legs is restricted. The most common cause of narrowing of the arteries which leads to chronic ischemia of the lower

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, Japan) and transferred onto PVDF membranes (Thermo Fisher Scientific). All samples were purified proteins and ALP containing fucosylated *N*-glycans was used as a negative control. After blocking with PVDF Blocking Reagent for Can Get Signal (NOF, Tokyo, Japan), the membrane was incubated with FasMab, mouse anti-AFP mAb Clone 2B12, or the anti-ALP mAb (Rockland Immunochemicals). The membrane was washed with TBS containing 0.05% Tween-20 (TBS-T) and then incubated with peroxidase-conjugated secondary antibodies. After washing with TBS-T, the proteins were detected with an ECL kit (GE Healthcare). The conditioned media of wild-type and *FUT8*-deficient HepG2 cells were condensed and protein concentration was quantified by using a bicinchoninic acid (BCA) protein assay kit (Nacalai tesque, Kyoto, Japan). Twenty micrograms of total protein included there was subjected to 10% SDS-polyacrylamide gel electrophoresis, and then transferred to a PVDF membrane (Millipore, Billerica, MA). After blocking with PBS containing 3% BSA or 5% skim milk, the membrane was incubated with FasMab, mouse anti-AFP mAb Clone 2B12 or biotinylated *Aleuria aurantia* lectin (AAL; J-Oil Mills). AAL was used for detection of fucosylated proteins contained in the conditioned media. AAL recognizes all types of fucosylation, that is, α1,2-, α1,3-, α1,4, and α1,6-fucose-containing oligosaccharides^[@CR22]^ but it is reported that it preferentially binds to α1,6-fucosylated oligosaccharides^[@CR23]^. The membrane was washed with TBS-T and then incubated with peroxidase-conjugated anti-mouse IgG for western blotting and incubated with avidin-peroxidase conjugates (ABC kit, Vector Laboratories, Burlingame, CA) for AAL blotting. After washing with TBS-T, the protein bands were detected with an ECL kit (Wako, Osaka, Japan). Human serum samples {#Sec16} ------------------- In this study, 25 normal human serum samples were purchased from ProMedDx (Norton, MA, USA), 20 liver disease serum samples were purchased from BioreclamationIVT (Westbury, NY, USA), and 55 AFP-positive HCC serum samples were purchased from Access Biologicals (Vista, CA, USA) and BioreclamationIVT (Westbury, NY, USA). The serum samples purchased from Access Biologicals, ProMedDx and BioreclamationIVT have been collected through obtaining informed consent from each donor and under protocols approved by Independent IRB (Sunrise, FL, USA), New England Independent Review Board (Needham, MA, USA) and Schulman Associates IRB (Cincinnati, OH, USA) respectively. All experimental protocols were approved by the research ethics review committee of Sysmex Corporation in accordance with Ethics Guideline for Clinical Research. The AFP concentration and AFP-L3% of human serum samples were measured using µTAS WAKO AFP-L3^[@CR9]^. The AFP-L3 concentration was determined using the following equation:$$\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\rm{t}}{\rm{o}}{\rm{t}}{\rm{a}}{\rm{l}}\,{\rm{A}}{\rm{F}}{\rm{P}}\,{\rm{c}}{\rm{o}}{\rm{n}}{\rm{c}}{\rm{e}}{\rm{n}}{\rm{t}}{\rm{r}}{\rm{a}}{\rm{t}}{\rm{i}}{\rm{o}}{\rm{n}}\times {\rm{A}}{\rm{F}}{\rm{P}}-{\rm{L}}3{\rm{ \% }}.$$\end{document}$$ Immunoprecipitation and western blot analysis {#Sec17} --------------------------------------------- For immunoprecipitation experiments, 25 μL of protein G sepharose FF (GE Healthcare) was incubated with 10 μg of a goat anti-AFP polyclonal antibody (LifeSpan Biosciences) at RT for 1 h. The resin was washed three times with PBS, and incubated with 200 μL of human serum at 4 °C overnight. After washing five times with PBS, bound proteins were eluted with 50 μL of 0.1 M glycine-HCl (pH 3.0). The solution was neutralized with 5 μL of 1 M Tris-HCl (pH 9.0). Ten microliters of the solution was electrophoresed on 10--20% Tris-glycine gradient gels (ATTO) and transferred onto PVDF membrane (Thermo Fisher Scientific). Western blot procedures were performed as purified proteins described above. Primary antibodies used included FasMab and 2B12. The band intensities were analyzed with ImageJ^[@CR24]^. ELISA {#Sec18} ----- The glycopeptide-binding activity of the FasMab was assessed using antigen-immobilized ELISA. Two micrograms per milliliter of BSA-conjugated fucosylated or non-fucosylated AFP peptides (Fig. [2](#Fig2){ref-type="fig"}) diluted in phosphate buffer (pH 7.5) was coated onto 96-well plates at 4 °C overnight. The wells were washed with PBS-T and blocked with 1% BSA in PBS at RT for 3 h. The plates were then washed and incubated with 125 ng/mL of FasMab diluted in 1% BSA in PBS at RT for 1 h. The wells incubated with FasMab were washed, followed by addition of goat F(ab')~2~ fragment anti-mouse IgG (H + L)-peroxidase (Beckman Coulter, Brea, CA, USA). The enzymatic reaction was conducted using TMB substrate. Optical density was measured at 450 nm using an iMark Microplate Absorbance Reader (Bio-Rad). The measurements were performed in triplicate. All data was plotted using GraphPad Prism 6 software.Figure 2Epitope mapping of FasMab using ELISA. (**A**) Schematic representation of AFP glycopeptides. Positions of mutated amino acids are shown in red. Blue squares, green circles, and red triangles correspond to *N*-acetylglucosamine, mannose, and fucose, respectively. (**B**) Bar graph illustrating the reactivity of FasMab to the different AFP glycopeptides illustrated in (**A**). Error bars represent the standard deviation. The binding activity of FasMab for entire AFP protein was assessed using sandwich ELISA. FasMab (5 μg/mL) diluted in phosphate buffer (pH 7.5) was coated onto 96-well plates at 4 °C overnight. The wells were washed with PBS-T and blocked with 1% BSA in PBS at RT for 3 h. Then, the plates were incubated with fucosylated AFP, afucosylated AFP, AFP from wild-type or *FUT8*^−/−^ HepG2 cells diluted in 100 mM 2-Morpholinoethanesulfonic acid (MES) (pH 6.0) and 4 mM Tris (2-calboxyetyl) phosphine chloride (TCEP) at RT for 1 h. The wells were washed and ALP-conjugated 2B12 was added. ALP conjugation to 2B12 was performed using an Alkaline Phosphatase Labeling Kit-SH (DOJINDO, Kumamoto, Japan). After incubation at RT for 1 h, the wells were washed, and ALP substrate was added to the wells. Optical density was measured at 595 nm using a SpectraMax 190 Microplate Reader (Molecular Devices, San Jose, CA, USA). The measurements were performed in triplicate. All data was plotted using GraphPad Prism 6 software. Surface plasmon resonance (SPR) {#Sec19} ------------------------------- Fab fragments of FasMab were prepared using immobilized Papain (Thermo Fisher Scientific) according to the manufacturer's instructions. The interaction between fucosylated AFP and the Fab fragment of FasMab was analyzed by SPR using a Biacore X100 instrument (GE Healthcare). Fucosylated AFP was immobilized onto the surface of a CM5 sensor chip (GE Healthcare) using a standard amine coupling procedure. The kinetic data of the binding of the Fab of FasMab to antigen were obtained by injecting increasing concentrations of antibody into the sensor chip at a flow rate of 30 μL/min. Contact and dissociation time were 180 sec and 600 sec, respectively. The measurements were carried out at 25 °C in 50 mM MES (pH 6.0) 50 mM NaCl, 4 mM TCEP, and 0.005% Tween-20. Data analysis was performed with the Biacore X100 Evaluation software. Association (*k*~on~) and dissociation (*k*~off~) rate constants were calculated by a global fitting analysis and stoichiometry of (1:1). The dissociation constant (K~D~) was determined from the ratio of the kinetic rate constants as follows: K~D~ = *k*~off~/*k*~on~. Sandwich immunoassay for measurement of fucosylated AFP on an automated chemiluminescence enzyme immunoassay analyzer {#Sec20} ---------------------------------------------------------------------------------------------------------------------

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agreements. See the NOTICE file # distributed with this work for additional information # regarding copyright ownership. The SFC licenses this file # to you under the Apache License, Version 2.0 (the # "License"); you may not use this file except in compliance # with the License. You may obtain a copy of the License at # # http://www.apache.org/licenses/LICENSE-2.0 # # Unless required by applicable law or agreed to in writing, # software distributed under the License is distributed on an # "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY # KIND, either express or implied. See the License for the # specific language governing permissions and limitations # under the License. class MouseButton(object): LEFT = 0 MIDDLE = 1 RIGHT = 2 Predictive value of specimen radiography for core needle biopsy of noncalcified breast masses. Our objective was to determine the predictive value of specimen radiography for large core (14-gauge) needle biopsy of noncalcified breast masses. Eighty-four biopsies of 83 breast masses yielded 403 specimens. Specimens showing dense material on specimen radiography were predicted to be diagnostic; specimens showing intermediate- or low-density material were predicted to be nondiagnostic. Specimen radiographic and histopathologic findings were correlated for each specimen using vital dyes to mark individual specimens. Of the 403 specimens, 307 (76%) contained diagnostic material representative of the lesion, with a specific diagnosis achieved for 82 (99%) of 83 lesions (62 benign, 20 malignant). Of the 293 passes containing dense material, 268 (91%) proved to be diagnostic; 11 (18%) of 62 specimens containing only low-density material proved to be diagnostic. Of the 25 (9%) of 293 specimens containing radiographically dense but nondiagnostic material, 18 (72%) showed focal fibrosis and had missed the lesion; 15 (83%) of 18 such specimens were obtained in dense parenchyma. The positive predictive value of specimen radiography was 13 (100%) of 13 in fatty breasts; 77 (96%) of 80 in breasts with minimal scattered fibroglandular elements; 91 (94%) of 97 in heterogeneously dense breasts; and 35 (70%) of 50 in breasts with extremely dense parenchyma. Of the 16 lesions sampled stereotactically, specimen radiography helped assess the inadequacy of initial sampling in three (19%). In six (9%) of 68 sonographically guided biopsies, only one or two specimens could be obtained; specimen radiography helped us predict whether material was adequate for diagnosis. Radiography of core specimens obtained from noncalcified breast masses accurately reveals the adequacy of sampling unless the breast parenchyma is extremely dense. Such immediate assessment can help ensure adequate material from lesions that are difficult to biopsy and can thereby improve the diagnostic yield of large core needle breast biopsy.You are here Talisay Police to Probe Teener’s Death Talisay City PNP authorities are conducting investigation on the mysterious death of a 19-year-old male found in Purok Sigay, Barangay Zone 3, Talisay City around 7:00 a.m. Sunday. The victim was later identified by police authorities, according to Superintendent Adonis Rosales, as Orlando Salazar Jr., whose body was found in a nipa plantation in the area already in a state of decomposition. He sustained a lone hack wound on his back. According to his mother the victim was last seen roaming in the fish port two days before his body was found. Police also alleged that the victim had previous cases of theft in the village and was previously sniffing solvent.*Q: Do any Nikon FX cameras allow square-format shooting with DX lenses? When one uses a Nikon DX (APS-C) camera on an FX camera body, the camera automatically enters a "DX crop mode", using only the center portion of the sensor to match the DX format, as explained on Nikon's web site. The FX format is roughly 36×24mm, while DX is 24×16mm, and it's this smaller size that DX crop mode uses. Notice that the short edge of the FX format is equal to the long edge of DX — and of course the image circle is perfectly round, not oblong. Do any Nikon full-frame cameras allow a "square DX" format, either 24×24mm (with some possible vignetting in the extreme corners) or slightly reduced? A: Square format is not supported, but 5:4 aspect ratio offered by D3, D3s, D800 and D800E is only slightly wider, 30mm. The nice thing is that the viewfinder is electronically masked, so you can compose with good precision. This aspect ratio is not provided on a D700 or D3x. Alternatively, you could always crop in post. Of course, you'll also need to disable Auto DX Crop. The Blyth Hotel Simple yet stylish, the Blyth is contemporary seaside hospitality at its best; designed to be welcoming but informal, giving you the luxury of relaxing into Southwold living. A delightfully refurbished family run hotel just 5 minutes walk from Southwold’s famous colourful beach huts or the town centre. All of our 12 bedrooms with en-suite bath or shower, have been elegantly styled during a recent refurbishment. As a family run business, we offer attention to detail in every way and guarantee you’ll find it hard to leave.Headlines Bruins seek split of home-and-home vs. Sabres by Mike Battaglino / NHL.com SABRES (9-23-3) at BRUINS (23-10-2) TV: MSG-B, NESN Last 10: Buffalo 4-4-2; Boston 7-3-0 Season series: The Buffalo Sabres defeated the Boston Bruins 4-2 on Thursday after trailing 2-1 late in the second period. Boston won the first game, also at Buffalo, 5-2 on Oct. 23, with two third-period goals from defenseman Torey Krug. Big story: Buffalo has won two in a row in regulation for the first time this season; it has not won three in a row in any manner. Of the Sabres' nine wins, three are against the Bruins, Los Angeles Kings and San Jose Sharks (sixth, fourth and seventh in the NHL standings prior to Saturday). "I expect [Boston] to probably be a little upset about the loss," Sabres defenseman Mike Weber told the team website. "I think we've always played them hard and it's always been a hard-fought game. I'm not too worried about anything. It's always better when you're into the game when people are hitting you and you're hitting them back, and you're into the battles in front of the net." Team Scope: Sabres: Buffalo acquired forward Linus Omark in a trade Thursday and will put him to work Saturday. "He'll take a spot in the lineup," interim coach Ted Nolan said Friday, according to the Buffalo News. "I'm not 100 percent sure exactly where we'll put him yet but he'll play tomorrow night." The Sabres are short a forward after Cody Hodgson sustained a wrist injury blocking a shot by Krug in the first period Thursday. Nolan said Hodgson would be out "maybe a week or two or three. I'm not sure." Omark, 26, played one game this season for the Edmonton Oilers, who received a conditional sixth-round draft pick in return. He was fourth in the American Hockey League with 29 points in 29 games for Oklahoma City. "He's getting pretty close," coach Claude Julien told the Boston Herald after practice Friday. "Honestly it's a matter of game-to-game right now. I don't know yet [about the game Saturday], but I wouldn't write him off." McQuaid hasn't played this month because of a lower-body injury reported to be a groin pull, missing eight games (5-3-0). The Bruins could wait until after the three-day Christmas break to give him a little more recovery time. "I hope that's not the case," McQuaid told the Herald. "I want to be back playing as soon as I can. I definitely don't want to be going through that cycle of coming back a little bit too soon [and getting hurt again]. But when I'm ready, I'll be ready. Hopefully that's sooner rather than later." Who's hot: The Sabres have killed 14 penalties in a row; they haven't allowed a power-play goal since Dec. 5. Forward Brian Flynn has three of his season's six points in the past two games. Forward Drew Stafford has three points in four games, including his first goal since Nov. 5. Defenseman Christian Ehrhoff has five points in the past six. … Bruins forward Brad Marchand had two goals Thursday, and defenseman Zdeno Chara had two on Tuesday. Forward David Krejci has 11 points in his past 10 games. Share this!! The NHL uses cookies, web beacons, and other similar technologies. By using NHL websites or other online services, you consent to the practices described in our Privacy Policy and Terms of Service, including our Cookie Policy.Independent UX Consultant & Mobile Special

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for me. Whenever I needed to talk to him, whenever I needed help. Again, he was always patient. He was a good friend. I am very glad that I not only got to know Karry Moore but I can say he was a friend to me and my family and because of our friendship I am a better person. Please remember, that we NEVER know when it all comes to an end… but we all know it will end. Do not waste time with the stupid B.S. that life throws at you. In the end NONE OF IT MATTERS. What matters is family, friendship, relationships and love. I do regret that I didn’t spend more time with him. We talked in the past of visiting each other more but I live in Philly and he lived in Florida and we both ran national companies and we both had families… we had great reasons. And when he got sick, I wanted to visit him but he said that he thought I should wait until he got a little better. Every time I asked, he said he wanted to get a little more healthy before I came and visited with him. I am upset that I didn’t book a flight and just go! Just Google "How To Buy a Car" or YouTube "How To Buy a Car" and what you see on the FIRST page is THIS video (The Original One). This video is from 2007, its HORRIBLE, ITS Filled with lies and misconceptions. The speaker is obviously NOT an Automotive Sales Expert... What seriously disturbs me is that NO ONE is doing anything about this... NO ONE? No OEMs, No Dealer Groups, No Dealerships, No Automotive Managers, No Automotive Sales Consultants... No one. There is this stupid propaganda video LOCKED online and it just sits there without challenge? I am not sure about you but this video offends me, it has always offended me. Because it is so one sided and so filled with mistruths and straight out lies... What is sad is that the PUBLIC sees this as REAL, as the TRUTH. Why...? Because it is on the FIRST page of Google and the First Page of YouTube!!! Most people are NOT subject matter experts. They are going online for some information, some direction and then they stumble into this type of trash... What is SAD is that they actually believe it. And why shouldn't they...? Its not like there are other, more compelling videos that tell the REAL story. So, if you are watching this video or reading this post with distain... DO SOMETHING ABOUT IT! Here are a bunch of ideas of articles, blog posts or VIDEOS you could write, record and POST all over the internet: * How To Buy a Car? * How to Buy a New Car * How to Buy a Used Car * What to expect from Car Dealership * What makes a GREAT Car Dealership * How Do you Choose a specific Car Dealerships These are just some basic ideas. The point is CREATE CONTENT, INFORMATION to the PUBLIC. Stop just thinking the internet is a "Point of Sale" resource... You need to capture people at "Point of Interest" and CULTIVATE the opportunity. If you are as pissed as I am when watching this video... Let me know your thoughts- Have you ever looked at the clock and seen it was the end of your shift and you thought to yourself, “Wow — where did the day go?” Or worse, “Uh oh, I got absolutely nothing done today.” Well, you are not alone; most people in our industry feel the exact same way. Automotive professionals sometimes describe working at a dealership as “chaotic,” “a constant fire drill,” “not organized,” “overwhelming,” “stressful,” etc. A lot of dealerships feel like they are grinding to sell cars, but wonder why they constantly fail to hit their objectives. They are confused why they are not selling as many units as they need to, even though they have their team working bell-to-bell most of the month. There is a logical reason of course: They have no understanding or training when it comes to proper time management. Remember, there are only 86,400 seconds in a day. When they are gone, they are gone. For the most part, most dealerships just “react” versus being “proactive.” You can get up and have a positive attitude and want to work really hard, but if you have no plan, you can’t expect to be tremendously successful. Don’t get me wrong — I am sure you can have some success. It will only be short lived, however, or not at the full magnitude that you are capable. Here is an example: If I said to everyone reading this AutoSuccess article that I am giving away $1,000,000 to anyone who can drive from Houston, Texas to Philadelphia, would you be in? Of course you would be. But here is the catch: You can only use this map that I give you. Are you still in? Of course you are. But there is more to the catch. The map is of the city of San Francisco. Uh, oh. That changes everything, because the rules of the $1,000,000 giveaway is that you have to use this map and only this map. So how in the world are you going to get this easy million dollars? Oh, I know: You can have a great attitude. You can think positively, and you can be happy about the opportunity. Is that going to help you accomplish that goal? No. A positive attitude is great, but it is not enough in this example, and it is not enough in the real world at your dealerships. OK, how about working hard? If you work really hard at looking at this map of San Francisco, maybe you can unlock some secret rout to Philadelphia from Houston? No, you can’t. So, working hard is important, but it is not the sole answer. You need to have a map; you need an internal global positioning system (GPS). You need to begin with the end in mind. Car dealerships are awesome, but they are hectic; there is a lot going on. Plus, it is a month-to-month business. I get it. You need, though, to take control of what you have control of — yourself. We all have multiple roles in our life. We are not just automotive professionals. Some additional roles that you might fall into include: • Parent • Son/daughter • Brother/sister • Manager • Leader • Owner • Trainer • Motivator • Analyst • Friend • Volunteer • Veteran • Paramedic • Athlete • Pet owner • Community activist • Baby Sitter (which can have multiple meanings…) So, now take into account how busy your day is, how hectic a dealership is, how intense our industry is and now add all of the roles you play in life. How are you juggling everything? Are you even trying to juggle or are you neglecting important things? There is a better way. Internationally respected leadership authority Dr. Stephen Covey says that the most effective planning is weekly planning — not monthly or daily. It is truly best to pick a time once a week (my wife and I prefer Friday, after work) and map out the following week. The key is not to overload or “pack” as much as possible into a short amount of time. Rather, you want to identify your priorities — a.k.a. “must do’s” — and schedule them first. This should include your different roles. You want to make sure that you put first things first. Here are some examples: • Showroom appointments • Training sessions (can be from the dealership or on your own) • Phone call and follow-up time • Breaks, lunch, etc. (it is important to refresh yourself and “sharpen the saw”) • Any days off • Clients anniversaries, birthdays or other important dates • Personal friends’/relatives’ anniversaries, birthdays or other important dates • Special time with family (and or friends) • Health appointments (doctors etc…) • Relaxation time If you have any questions about this article or would like some advice on how to create a powerful weekly planning road map, please feel free to call me or e-mail me. Sean V. Bradley is the founder and CEO of Dealer Synergy, a nationally recognized training and consulting company in the automotive industry. He can be contacted at 267-319-6776, or by e-mail at [email protected]. The rules have changed in automotive SEO. In fact, they've changed for the entire search engine optimization world. It's no longer a function of quantity that determines rankings. More content, more links, more social signals - that's fine, but it won't help you as of April 24, 2012, the way it used to. Today is the world of SEO quality over quantity. These changes have been anticipated for some time but only now are they really becoming apparent. Some dealers are dropping in rankings based upon their (or their vendor's) SEO efforts. As a result, others are moving up. Which side of the fence do you want to be on? Here are some best practices to help you get on the right side of the fence. Click to enlarge. A Mercedes-Benz dealership

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. He put the gun in his pocket and returned to the kitchen. Quickly he cleaned up all but a few tiny shards of glass and dumped the fragments into a garbage can just outside the kitchen door. He went back to the one bedroom which looked in use. Double-bed with a yellow spread -- neat. A couple of small chairs. A vanity, dresser and mirror, beige carpet wall-to-wall and... Where the carpet came out from under the bed by one of twin night tables, a large irregular stain, faded by much scrubbing. Blood? No time for speculation. He began to open drawers, finding only female garments in the vanity, male in the dresser. He went to one of two closets and discovered an array of dresses and shoes, fine quality. He was headed for the second when he had a strange feeling of presence in the room. He froze in stride and slowly turned his head. His gaze fastened on the doorway. Framed in the center with a curious look of placid watchfulness was Valerie McLean. She was dressed in slacks and a white jersey which followed snugly the lift and thrust of her breasts. She wore tennis sneakers. Though she was rigidly immobile, she leaned on the doorframe with apparent casualness. Slowly he let the gun sink back into his pocket and removed his hand. He didn't know what to say except, "Hello, Valerie." "It took you a long time," she said. "Not so long. A few days." "How you must have worked at it," she said, still unmoving. "And how clever you must have been." "I had luck here and there. Or I might never have found you." "How clever," she said again. "And how foolish." "Foolish?" "Why couldn't you tend to your own silly life and let others live theirs the way they have to live it?" "Have to?" "Have to. We do what we have to do." Her voice broke and trembled on the edge of breaking. "I feel sorry for you," she said. "For me?" She nodded. "And for me, and for -- for everyone." She made no sense at all. "Where were you just now?" he said. "I know the house was empty. Where did you come from?" "In the front door," she said, her voice gaining control. "And before that?" "Does it matter?" "Are you alone?" His hand went back to the pocket. "You don't see anyone else, do you?" "It's the ones I don't see that worry me." "If I wasn't alone, you would have known it before now." "Just the same, we'll look around," he said, and this time the gun came out of his pocket. She looked at the gun with small interest. "How thoughtful to be always prepared." "Just walk ahead of me and make the tour, Valerie." Behind her, he went from room to room. He looked outside, front and back. "Now," he said. "We'll start with the other bedroom and we'll take everything out of the drawers and closets. You'll do the work, I'll watch." With a shrug, she preceded him. As they went from room to room, she silently opened the emptied drawers and closets just as he ordered. Her attitude was stoic, resigned. He found nothing incriminating in any corner of the house. They returned to the living room and he sat down facing her with the gun restored to his pocket. "Well," he said. "I didn't really expect to find the money. But I did expect to find some little thing. It's over, Valerie. Completely over. Why don't you just tell me?" "I never seem to know when a thing is over," she said. "That's my trouble. Would you mind giving me a hint as to what got you started on all this?" "I was watching in the mirror when you opened the suitcase. Very few honest people can get that much cash together." "I see. Very stupid of me. But I was so upset." She laughed without humor. "In a way, I paid you five hundred dollars to hunt me down." "Oh, I'll return it," he said. "But not to you. What happened to Roy Whalen, Valerie?" Her face underwent the first real change. "Don't look so startled. I have most of the facts. He and Marty Bates did it together. With Scofield's help, of course. Isn't that right?" "I only listen." "You don't seem the type for this, Valerie. What are you all about? I'm really curious." "You know what they say about curiosity, don't you?" The question came from another part of the room and the voice which asked it was distinctly male. Clayton Scofield stood in the archway of the dining alcove. The round cold mouth of the .45 in his fist dared Scott to move for his own gun. He didn't. "Oh, thank God!" sighed Valerie. "I thought you'd never get here." "Your call caught me with a customer waiting. I had to lend him some money to get rid of him. He was a very bad risk." She got up and went towards him. "No," he said. "Don't get in my way." She paused. "He's got a gun," she said. "Is that so? Stand up, Daniels. And step away from the chair." He obeyed. "Get the gun, Valerie. Walk around him and reach from behind. That's it." Fingers groped and found the .32. She delivered it and it disappeared in Scofield's pocket. "Sit down again, Daniels," Scofield ordered. "How did you know I was here, Valerie?" asked Scott from the chair. His own voice sounded immensely calm while his palms were fear-damp. "Luck," she said with a wry smile. "I was bored and I had gone for a walk. I was just rounding a corner and there you were getting out of the car. I ducked back and watched until you were out of sight. Then I went in and called Clay. While I was talking to him, I heard the back window crash and I went out the front door." "I told you to stay outside and wait for me," said Scofield. "You were taking a chance." "I wanted to keep him busy," she said. "I was afraid he'd leave." "Well," Scofield said, "this doesn't change anything. It only convinces me he's a very bad boy to have around." "He knows much more than we dreamed," said Valerie. "He knows about Marty. And he knows about Roy, too." "Nonsense!" said Scofield. "If he knew you killed Roy he would have brought the police with him." "Oh God, oh God," she moaned. "He didn't know Roy was dead, just that he helped." "What difference does it make?" snapped Scofield. "He already knew one thing too many." "The police know, too," said Scott in the shocked, near whisper which was all he could muster. "Don't try anything with me, Scofield. They know I'm here and they're watching this house." "Save your breath," said Scofield. "I'm familiar with how the police operate. When they have anything, they move right in and make an arrest. Is that his Ford around the corner, Valerie?" "Yes. The gray one." "Let's have the keys, Daniels." He hesitated. "Come on, come on!" He got up, found the keys and began to walk forward with them. "No you don't," said Scofield. "Throw them. None of your boy-scout ideas will work with me. Just remember that." Scott gave the keys a toss. Scofield caught them neatly in his left hand and dropped them in his pocket. "Back in the chair, Daniels." Scott returned, said quickly, "Listen to me, Scofield. Listen carefully. At thirty-five minutes after ten this morning I called a cop by the name of Hoag, Detective William Hoag. I told him everything I know. He followed me up here. Right at this moment he's out there somewhere, waiting for you to make a move. He had a radio car and he's in touch with headquarters. The smartest thing for you to do is...." "The smart thing for you to do is shut your mouth," said Scofield. "You have a dangerous tendency to make me nervous. You think I came this far just to let a small-time sonofabitch like you wreck everything I've done? Two other flunkies stood between me and a half million. You saw what happened to one of them." Stall, stall! thought Scott. "And where's the other one?" he

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</nav>  <div id="content">  <nav class="navbar navbar-expand-lg navbar-light bg-light"> <div class="container-fluid"> <button type="button" id="sidebarCollapse" class="btn btn-info"> <i class="fas fa-align-justify"></i> </button> </div> </nav>  <div class="row"> <div class="col-12"> <div class="card shadow mb-5"> <div class="title-holder"> <h1 class="title">Language Use in India</h1> <p class="subtitle">Calculated in the Millions</p> <p class="font">Uncheck labels to recalculate.</p> </div> <div class="card-body"> <div id="pieChart"> </div> </div> <footer> <ul class="footer"> <li><a href="http://www.censusindia.gov.in/Census_Data_2001/Census_Data_Online/Language/Statement5.aspx" target="_blank">Data Source</a></li> <li><a href="www.lisaofalltrades.com" target="_blank">lisaofalltrades.com</a></li> </ul> </footer> </div> </div> </div>  </div> </div>  </div>    <script src="js/script.js"></script> </body> </html> I've researched on how to use the d3.schemeCategorry20c it seems there is no problem in the way i used it was wondering what could be the problem. Any help will be so much appreciated. A: Change var color = d3.scaleOrdinal(d3.schemeCategory20c); to var color = d3.scaleOrdinal(d3.schemeCategory10); and error should be gone for you There is no more schemeCategory20c in d3.v5 Pages Meta While I wasn’t initially going to include this film, I was watching TCM the other night, and learned some new information about it that made it a whole new film to me. It’s not that I don’t enjoy the film, but there are other films that I think deserve a little more attention. See, this film is everyone’s favorite film and, to a certain extent, this little piece of information that I learned on TCM is the reason why! 7) It’s A Wonderful Life (Frank Capra, 1946) Inspired by an unsuccessful short story called “The Greatest Gift” by Philip Van Doren in 1939, Frank Capra’s film was released with a great less of a successful response than originally anticipated. While some attribute that to its dark themes or non-linear narrative, it also was going against super patriotic films like Best Years of Our Lives (William Wyler, 1946) , which definitely gave it a run for its money. So how did this film make the jump to becoming one of the most loved films in all Christmas-film-history? Simply put, the answer to that question is copyright issues and television. The film, released in 1946, was guaranteed protection under standard U.S. Copyright Protection laws for 28 years. So when 1974 came around, the film came up for copyright renewal. Within that time period, the film was only allowed to be played with proper permission and through proper dispensations, lest the individuals who wanted to show the film get in trouble for copyright infringement. However, when 1974 rolled around, Republic Pictures, the original copyright holder, dropped the ball and didn’t renew the copyright. This started a media chain reaction that caused the film to become as fundamental to the Christmas world as Apple Pie is to the US image. Long story short, It’s a Wonderful Life became public domain and shown on just about every channel on television during Christmas time for many years. You couldn’t switch a channel without seeing Donna Reed’s face. If it wasn’t for this little “accident” of Republic’s (which was “fixed” a few years later, thus why it doesn’t get played as such a multi-channel orgy as it had previously), this film would not be anywhere near as popular. Joe Dante is one of the nicest and most knowledgeable guys you’ll ever meet in your life. From the first time he ever programmed a festival at the New Beverly in 2008 (discussed here by the inimitable Dennis at Sergio Leone & the Infield Fly Rule), I knew he was one of the “good ‘uns.” Realistically, I had known this since I was a kid, but I reserve judgement on someone’s person until I get a chance to meet them (if I get that good fortune- which is rare- but in LA…it happens). However, Joe is absolutely golden. But I really should’ve known that since this was the man who gave us Matinee (Joe Dante, 1993), a film that has a lightly-disguised William Castle-like character (and I’m a huge Castle fan) and is dedicated to the undying love of cinema. I also should’ve known this since I remember seeing Innerspace (Joe Dante, 1987) with my mom in the theater as a kid and thinking it was one of the coolest movies ever, adoring the Sam Cooke song, and thinking that is this was what movies were about, I wanted to see ALL OF THEM all of the time. And yes, I’m a huge fan of The ‘burbs (Joe Dante, 1989) as well. I was so very pleased to get to see that at the New Beverly a little while ago as well. But, as we are all aware, the erudite Dante made a Christmas film. And it is not just any Christmas film, it is the Christmas film. 5) Gremlins (Joe Dante, 1984) One of my friends is probably the ultimate anti-Christmas-film person. He’s down with the food, but the “happy happy joy joy” stuff and any kind of religiousness? Keep that the hell away from him. It’s just not his style. But he loves Gremlins. He really, truly adores this film like it was going out of style. And considering some of his other favorite directors are Tod Solendz, John Woo and Werner Herzog and he believes that Salo by Pasolini is a staple…this is saying quite a bit. He’s not alone, however. Gremlins is widely considered a classic. And I think it’s generally because not everyone likes Christmas in its Joyful Portrayal. See, every bright room has some dark time, and to many people (myself included) the dark time is, in many ways, a great deal more interesting. In fact, if you were to take a look at the other “classic” Christmas films, they are all a bit dark, which leads me to question why we have so much trouble recognizing that. I mean, to be completely honest, It’s a Wonderful Life (Frank Capra, 1946) is a film about a guy who wants to commit suicide. How cheerful a theme is that around holiday time? Polish Gremlins poster. I love Polish posters. A man I wrote about a few entries earlier, Bob Clark, has dipped into the “dark time” of the Christmas room twice, with Black Christmasand with A Christmas Story (Bob Clark, 1983). While the latter film is more comedic, it has more edge than a straight-up, feel-good comedy. Most of the film centers on the gun that the child-protagonist wants, and how his parents think that it will “shoot his eye out,” not to mention the rest of the dark things that happen to the young members of the cast. Are we supposed to injure children in Christmas films? Heh. Well, maybe in my kinds of Christmas movies. As long as they’re accompanied by the right balance that Clark gives us (which he definitely does, in Christmas Story– if you haven’t seen that one, see it). Gremlins has monsters in it. And lord help me, I’m a sucker for a monster movie. I don’t care what season it is. And, more importantly, it has the significant interplay between human, monster, and sympathy. The things that will always get me. You put those things in a film, and more often than not, I’m YOURS. Then you add humor and a dark view of the holidays??? SOLD!! Gremlins has been on my list for these reasons and always will be. People can try to knock it, but they will always fail. In my mind, it is an essential. It wouldn’t be the holidays without

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F) was calculated from the rest and stress images using 4D QGS [@b17-cln_70p726] software, version 2012.2. Quantitative MBF Measurements ----------------------------- The studies were processed in batch mode using QPET (Cedars-Sinai, Los Angeles, California) to quantify MBF and CFR. In brief, left ventricle (LV) contours were positioned automatically with an algorithm that determines the LV contours from the summed dynamic images data. The 3-D cylindrical region (1 cm diameter, 2 cm length) for the LV input function was automatically placed in the middle of the valve plane and oriented along the long axis of the heart. Dynamic myocardial samples were obtained from the polar map by analyzing all of the time frames within the fixed LV contour boundaries [@b18-cln_70p726]. A standard 1-tissue compartment model was used to quantify MBF, which includes regional uptake and clearance parameters (*K~1~* \[mL/min/g of myocardial tissue\] and *k~2~* \[min^−1^\]), blood-to-myocardial spillover fraction and myocardial partial-volume corrections. A previously calibrated ^82^Rb extraction fraction was used to estimate MBF from *K~1~* [@b19-cln_70p726]. Stress and rest MBF were computed for each sample in the polar map, and CFR was calculated as the ratio of stress/rest MBF. Four basal slices were not used for flow analysis due to low counts in the membranous septum. MBF in each vascular territory was then obtained by averaging the polar map segments in the regions of the LAD, RCA, and left circumflex artery (LCX), according to the standard 17 segments of the American Heart Association model [@b20-cln_70p726] and corresponding to the anterior, septal, lateral, inferior, and apical walls. Image Interpretation -------------------- Rest and stress uptake images were visually analyzed using a 5-point score (0-normal; 1-mild uptake; 2-moderate; 3-severe and 4-no uptake) for relative myocardial perfusion in 17 segments [@b20-cln_70p726]. We compared the GI-A and GI-B patients considering the anterior and septal walls as segments 1, 2, 7, 8, 13, and 14 and the lateral and inferior walls as segments 3, 4, 5, 6, 9, 10, 11, 12, 15, and 16. Segment 17 was excluded in this analysis. Two experienced nuclear physicians who were blinded to the patient data analyzed the perfusion images. Summed stress scores (SSS), summed rest scores (SRS) and summed difference scores (SDS) were determined. An SSS ≥4 and/or SDS ≥2 were considered perfusion abnormalities. A rest or stress LVEF \<45% was considered to be abnormal. Statistical Analysis -------------------- Quantitative variables were expressed in medians (25%-75% quartile), while qualitative variables were expressed in percentages. Differences in the quantitative variables between GI and GII were verified by *t* or Mann-Whitney tests conditioned by the normality distribution assumption, which was checked using the Anderson-Darling test and the assumption of homogeneity of variances, which was established by the Levene test. In turn, discrepancies among GI-A, GI-B and GII were verified by ANOVA or Kruskal-Wallis tests, supported by the assumptions of normality and homogeneity of variances. Next, multiple comparisons relative to GI-A *vs*. GI-B and GI-B *vs*. GII were performed using the parametric or nonparametric Dunnett test [@b21-cln_70p726]. Comparisons of the anterior or septal wall with the other walls were evaluated using the paired nonparametric Dunnett test [@b22-cln_70p726]. Finally, differences in the qualitative variables were analyzed using the Fisher test. All of the discrepancies were classified as statistically significant considering a significance level at 5%. The calculations were performed using the *R* package, version 3.1.1. [@b23-cln_70p726]. Ethics ------ All of the procedures that were performed in studies that involved human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors. Informed consent was obtained from all individual participants included in the study. RESULTS ======= Clinical and demographic characteristics ---------------------------------------- The patient demographics are summarized in [Table 1](#t1-cln_70p726){ref-type="table"}. In GI patients, 12 had CAD (32%, GI-A) with 2- or 3-vessel disease in 67%, 1-vessel disease in 25% and a myocardial bridge in 8%. Twenty-six patients (68%, GI-B) had normal coronary arteries or \<70% stenosis and normal ^82^Rb-PET perfusion. The median ages were not significantly different (GI *vs*. GII, *p*=1.00; GI-A *vs*. GI-B *vs*. GII, *p*=0.06). The female gender was predominant in all groups. Furthermore, the main clinical risk factors, such as hypertension, dyslipidemia and diabetes, were also not significantly different between the groups. Quantitative MBF Measurements ----------------------------- Global and regional values in GI and GII are summarized in [Table 2](#t2-cln_70p726){ref-type="table"}. The stress flow and CFR were significantly lower in GI than in GII in all of the walls (*p*\<0.001), whereas the rest flow was lower only in the septal and apical walls (*p*=0.02 and 0.01, respectively). A comparison of the anterior or septal walls with the other walls in GI revealed that the rest flow, stress flow and CFR were significantly lower in the anterior wall and less so in the septal wall. However, the rest and stress flows were also significantly lower in the septal than in the inferior wall ([Table 2](#t2-cln_70p726){ref-type="table"}). A comparison between GI-A and GI-B did not show any significant flow differences, except for the global CFR (*p*=0.05) and could identify CAD in LBBB ([Table 3](#t3-cln_70p726){ref-type="table"}). Moreover, GI-A and GI-B had significantly lower stress flow in the anterior wall than in the septal wall. Thus, flow in the anterior wall was more affected by LBBB than that in the septal wall, independent of the presence of CAD. CFR in the apical and lateral walls were lower in GI-B than in GII, which could explain a pattern characteristic of LBBB in the absence of CAD. Myocardial Perfusion 82Rb-PET Imaging and LV function ----------------------------------------------------- Twenty-four patients in GI (63%) had no significant perfusion abnormalities and all patients in GII had normal perfusion. Moreover, the perfusion abnormalities (SSS ≥4 and/or SDS ≥2) tended to be more prevalent in the presence of CAD (GI-A *vs*. GI-B; *p*=0.06). We found statistically significant differences between the groups when we considered perfusion abnormalities in the anterior and/or septal walls (*p*=0.04) as well as in the inferior and/or lateral walls (*p*=0.003) ([Figure 1](#f1-cln_70p726){ref-type="fig"}). LVEF values and LV cavity volumes are summarized in [Tables 4](#t4-cln_70p726){ref-type="table"} and [5](#t5-cln_70p726){ref-type="table"}. Twenty-five patients in GI (66%) had LV dysfunction at rest and all of the GII subjects had normal LVEF. There were significantly lower rest and stress LVEFs in GI than in GII (*p*\<0.001), but no significant differences between GI-A and GI-B (*p*=ns). However, GI-A had a high prevalence of LVEF dysfunction (\<45%) only during stress (*p*=0.02). DISCUSSION ========== An evolution in cardiovascular imaging with PET-CT systems being incorporated into the clinical setting has been occurring since the early 2000s. This trend is partially driven by the fact that cardiac PET-CT offers a noninvasive method to assess relative myocardial perfusion, LV function, MBF and calcium score (15). The importance and independent prognostic values of MBF and CFR using ^82^Rb-PET, beyond relative myocardial perfusion image interpretation, has already been established. Worse patient outcomes and a higher incidence of cardiac events (death and myocardial infarction) have been demonstrated in cases with global CFR \<2 mL/min/g in patients with normal and abnormal relative myocardial perfusion [@b24-cln_70p726],[@b25-cln_70p726]. Despite the low prevalence of LBBB in the general population [@b26-cln_70p726], several studies have reported its frequent association with heart disease. In the Framingham study, CAD was found in 40% of LBBB patients and was associated with a fourfold increase in the risk of cardiovascular mortality [@b27-cln_70p726]. Dynamic alterations in the cardiac cycle produced by LBBB are known: asynchrony of contraction in the ventricles; reduction of LV diastolic

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demands and express them in absolute independence. Liberation was his objective, and liberation itself was a great cause, to free Spanish America from colonial occupation and its peoples from foreign laws. Liberty and equality, these were his pivotal themes, and he made them the foundation of his revolution. He thus advanced beyond those creoles who would have been satisfied with autonomy within the Spanish monarchy and whose commitment to equality was always dubious. He also led with the mind as well as the will. It was Bolívar, the intellectual, the political theorist, who gave Spanish American independence its intellectual underpinning, in works whose style and eloquence resound to this day. Liberty, he said, is 'the only object worth the sacrifice of a man's life', not simply freedom from absolutism but freedom from colonial power. From Montesquieu he inherited a hatred of despotism and a belief in moderate constitutional government, in the separation of powers and the rule of law. But liberty in itself is not the key to his political system. He distrusted theoretical concepts of liberty, and his hatred of tyranny did not lead him to the glorification of anarchy. 'Abstract theories create the pernicious idea of unlimited freedom,' he said, and he was convinced that absolute liberty invariably deteriorated into absolute power. His search for freedom therefore was a search for a mean between the extremes of anarchy and tyranny, between the rights of the individual and the needs of society. This would be secured essentially by the administration of justice and the rule of law, so that the just and weak could live without fear, and merit and virtue could receive their due reward. He believed, with Rousseau, that only the law can be sovereign, and law is the result not of divine or despotic authority but of human will and the sovereignty of the people. Equality too was a right and an objective in Bolívar's project. First, equality of Americans with Spaniards, of Venezuela and Colombia with Spain. This equality was absolute, and was the basis of his argument for independence. Second, equality between Americans. European political theorists wrote for communities of relative social homogeneity and appealed to fairly distinct classes, such as the petty bourgeoisie favoured by Rousseau. Bolívar had no such advantage. He had to begin with more complex human material and to legislate for a society with a special racial formation. Americans, he was never tired of saying, were neither European nor indigenous people but a mixture of Spanish, Africans and Indians. All differ visibly in the colour of their skin, a difference which places upon us an obligation of the greatest importance.' This obligation was to correct the disparity imposed by nature and inheritance, by making men equal before the law and the constitution. 'Men are born with equal rights to share the benefits of society,' he observed, but obviously they do not possess equal talents, virtue, intelligence and strength. This physical, moral and intellectual inequality must be corrected by laws, so that the individual may enjoy political and social equality; thus by education and other opportunities an individual may gain the equality denied him by nature. It was Bolívar's opinion that 'the fundamental basis of our political system turns directly and exclusively upon the establishment and practice of equality in Venezuela'. And he explicitly denied that this was inspired by France or North America, where in his view equality had not been a political dogma, a debatable opinion probably influenced by his determination to produce American solutions for American problems. The logic of his own principles led him to conclude that the greater the social inequality, the greater the need for legal equality. Among the practical steps which he envisaged was the extension of free public education to all the people and particular reforms for those sectors who were especially disadvantaged, such as the landless and the slaves. Liberty and equality, these were the essential objectives. But how could they be realized without sacrificing security, property and stability, those other rights by which society protected the persons and possessions of its citizens? In principle Bolívar was a democrat and he believed that government should be responsible to the people. As he moved into Venezuela to confront the rebellion of Páez in December 1826 he warned the people against warlords and their parties: 'Only the majority is sovereign; he who takes the place of the people is a tyrant and his power is usurpation.' But Bolívar was not such an idealist as to imagine that America was ready for pure democracy, or that the law could instantly annul inequalities of nature and society. Until our people acquire the political virtues of our brothers in North America, he said, I fear that popular systems of government, far from helping us, will be our ruin. He had no confidence in the people en masse as they came out of the colonial system; they had to be re–educated under the tutelage of a strong executive before they could be fit for liberty. Meanwhile: 'Complete liberty and absolute democracy are but reefs upon which all republican hopes have foundered.' He spent his whole political career developing his principles and applying them to American conditions in his own version of the age of revolution. 'His principle was not to expect too much from a people who unhappily might still be considered little better than a nation of slaves, to give them no more power than they were able to direct, and to have wholesome checks on those who held such power.' Until they were educated into political society his solution lay not in a federal system, which he consistently opposed, nor in monarchy, of which he was accused, but in his Bolivian Constitution, though even about this he was more diffident than is often supposed. Bolívar's revolution did not resemble revolutionary movements in Europe or the Atlantic world. These reflected conditions and claims which were appropriate to themselves but had only limited application to the political, social and economic problems of America. The European Enlightenment and its liberal aftermath, well known to Bolívar, were too self–absorbed to offer political ideas or services to colonial peoples. The economic interests of industrial Europe, being those of a metropolis, involved some opportunities for primary producers but also disadvantages, and if industrialization was a medium of social change in western Europe, it played no such role in early nineteenth–century Spanish America, whose concern was to strengthen the traditional export sector – and with it the landed oligarchy – in order to import manufactures made by others. For these reasons Bolívar, who in many respects had a deep affinity with the age of revolution, could not imitate its intellectual and political leaders, even had he wished to do so. While the Enlightenment confirmed his attachment to reason and inspired his struggle for liberty and equality, he had to employ his own intellectual resources to fashion a theory of colonial emancipation, and then to find the appropriate limits for liberty and equality, and in the process we can see traces of enlightened absolutism as well as democratic revolution. Democratic forms in Europe and North America evoked his respect, but he insisted on writing his own constitutions, designed to conform to Spanish American conditions, not to outside models. These conditions, especially in the post–war period, when social and racial divisions, lack of consensus and absence of political traditions placed liberal constitutions under severe strain and brought the new republics to the edge of anarchy, caused serious problems for Bolívar. Now we see the realistic Bolívar – his democratic ideals tempered by experience of popular protest, race conflict, and elite factionalism – the man who declared Spanish America to be ungovernable. The Bolivarian model of government, designed around the life presidency, appealed to the military but otherwise made few friends: it excluded too many vested interests from political life and decisions to gain wide acceptance. The civilian elites preferred more liberal constitutions, though even these and their authors were affected by that bias towards authority and centralism that was a feature of the republican as it had been of the colonial state. Most Venezuelan constitutions allowed the president extraordinary powers of intervention in time of crisis or rebellion, and most defined the political nation in the narrowest of terms, establishing property and literacy qualifications for those entitled to stand for election and even to vote. Bolívar had nothing to be ashamed of in any comparison of his constitutional principles with those of his liberal enemies. Historians have suggested that he abandoned the search for liberty, or at least postponed it in favour of order and security. But the evidence shows that his principles in 1828–30 were not basically different from those he had developed from 1812 onwards, that his insistence on liberty and equality was always accompanied by a search for strong government. Bolívar conceived the American revolution as more than a fight for political independence. He also thought of it as a social movement, which would improve as well as liberate, and would respond to both the radical and liberal demands of the age. For him a free government had to be an active government, moving beyond dispensing privileges and patronage into the more positive work of giving Americans a better life. Strong government was essential for the new states if they were to impose reforms, an incomprehensible synthesis for the liberals of his day, but better understood by later generations of Latin Americans. Many of them came to believe that powerful presidential government and one–party states were suitable, or at least inevitable, constitutional forms for new nations in formation. Bolivarian absolutism, therefore, was not an end in itself. The bias towards strong government, in the interests of reform as well as of order, and as a necessary framework for post–colonial development, was a quality rather than a flaw in Bolívar's policy, and endows him with a modernity beyond the confines of the age of revolution. ## _The Realist of the Revolution_ Bolívar did not promote a social revolution, and never claimed to do so. Land distribution, racial equality, abolition of slavery, pro–Indian decre

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s metabolism, but its concentration declines with age. It is not available as a supplement, to my knowledge. The best dietary source is a Japanese fermented soy product called natto, which is famous for its vile flavor. Other dietary sources include soy products and wheat germ. And yes, it is found at high concentrations in semen. Read more Alternative to Chemotherapy and Radiation Dr M Rigdon Lentz (an American) runs a German clinic with a unique cancer treatment. Cancer cells protect themselves from attack by the body’s immune system by spitting out many “false target” molecules that attract killer T cells in the blood and distract them from the real culprit, the cancer cells themselves. Lentz’s procedure involves filtering these decoy molecules from the blood. Often this is sufficient to initiate a fierce immune assault on the tumors, which flare up hot and red. Lentz described some dramatic cures. He reports major regression of tumors in 70% of his patients, despite the fact that most of them have been treated previously with chemo and/or radiation and traditional oncology has given up on them. Read more DRACO – kills all virus-infected cells Todd Rider of MIT is quietly witty on-stage and charmingly self-effacing, but his program is radically ambitious. He wants to cure all infectious disease. DRACO is an acronym for Double-stranded RNA-Activated Caspase Oligomizer. Start with the observation that single strands of RNA are used in all cells, but double-stranded RNA is found only in cells infected by viruses. The DrACO molecule has three parts: One part speaks to the body’s “mail system” that looks at address tags on a molecule, and uses those to send them to a particular cell. DRACO molecules are targeted to a particular kind of cell that is infected. Part two is a detector of double-stranded RNA. And if dsRNA is found, then part three is activated: molecular signals that trigger cell death. The bottom line is that DRACO molecules can find cells that are infected with any virus, distinguish them from uninfected cells, and selectively signal the cell to destroy itself. It’s been tested in test tubes and in mice it cures, for example, the flu. Rider’s lab is producing only tiny quantities of DRACO at present, but by year’s end he hopes to ramp up production for much wider testing. Read more RTEs = Retro Transposable Elements Half of our DNA consists of repetitious stretches of DNA that never get translated into proteins. This was once referred to as “junk DNA” or even “parasitic DNA”, but it probably plays an important role in evolution. One piece of evidence for this is that RTEs of recent origin (those unique to primates) are a lot more active and mobile. They’re the part of us that is presently evolving. John Sedivy of Brown University reported that senescent cells – cells that have depleted their telomeres – are far more likely to have active RTE’s. These DNA segments make RNA copies of themselves which can then be “retro-transcribed” back into the chromosome, with disruptive consequences. (Transcription = DNA→RNA, part of the path by which chromosomes control the cell; Retro-transcription = RNA→DNA, an unusual and often pathological process) Read more Retinoic Acid promotes regeneration of damaged tissue Retinoic Acid is an ingredient in prescription cremes which treat acne and also aging skin. Malcolm Maden from University of Florida reported that retinoic acid promotes regeneration generally. Read more Genetic therapy is much advanced Frank Church of Harvard reported on the state of the art in gene therapy. Fourteen years ago, the first gene transplant experiments resulted in death of a (very sick) teen patient, and set the field back several years. But advances in the interim make it possible now to insert a gene safely into a large number of cells of a lilving body, and target them to a precisely specified position on a chosen chromosome. This is done using CRISPRs, which are short stretches of RNA with a distinctive palindromic pattern, used by viruses to find the right place to insert themselves into a host genome.Read about CRISPRRead about Gene Therapy Plasticity of the brain Jean Hébert of Einstein Medical Center in New York is working to inject neural stem cells into the brain, to grow new nerves. This might seem like an impossible challenge. Nerve cells regenerate at a rate lower than any other cell type in the body, and even if we got them to regrow, how would they come to carry the knowledge and skills that we have acquired during a lifetime? Hébert reports a hopeful and amazing fact: In patients with brain tumors that destroy function in one part of the brain, another part picks up the function smoothly and without noticeable disruption. This has been noted with fMRI studies based on Boca’s area, which houses language. Read more Growing a liver on a lymph node There is a long waiting list for liver transplants. In the US, 90% of patients with liver failure will die before they get a transplant. Some have proposed transplanting livers from pigs. Eric Lagasse of Wake Forest Inst for regenerative medicine has another idea. He has had success growing new livers from stem cells in the patient’s body. Liver progenitor cells are implanted in a lymph node, which seems to provide a favorable environment for growth. In mouse models, 70% are able to grow a functional liver “ectopically”, meaning in a part of the body where it does not belong.Read more One of the oldest and best-established theories of aging holds that we age because of oxidative damage. In the classic version, the body exploits high-energy chemistry based on oxidation for an energy supply at the cellular level, but this involves constant exposure to these high-energy species and the free radicals that are their by-products, species which can attack sensitive biomolecules. Damage to these molecules accumulates over a lifetime, so the story goes, and makes the body gradually less able to maintain its balance. I’ve argued against the general idea that aging is an accumulation of damage, because of evidence that it is an active process, closely regulated like everything else about life. But new to me this week is a version of the theory by Spanish physiologist Gustavo Barja, in which some of the same chemistry is described as an active program of self-destruction. Barja argues that the process of burning fuel to produce energy can be extremely clean or it can be rather dirty. It is the “leakage” of free radicals during the process that causes the damage of aging, and this leakage can be quite fast, or it can be almost nil. Leakage is tightly-regulated in a way that determines life span. This is a unique lens through which to view aging. What does it help us to understand? An old and (I believe) discredited view of aging is that the body ages the same way a tool rusts or a car wears out over time – because damage accumulates with wear and exposure to corrosion. The best-established version of this theory is based on damage in the cellular energy factories, the mitochondria, and it is called the Mitochondrial Free Radical Theory of Aging, MFRTA. I visited last week with a man who has devoted his career to studying the chemistry of mitochondria, and he has come to believe that indeed mitochondrial chemistry has a lot to do with aging, but this is not just damage that accumulates as a side-effect of the energetic chemistry. He thinks that this damage is purposeful and programmed, and has written an updated version of MFRTA. Everything that you have heard about free radicals, ROS (reactive oxygen species) and anti-oxidants derives from the MFRTA. Mitochondria are tiny energy factories. Hundreds of them in each cell of our body burn sugar and convert the energy to an electrochemical form, analogous to charging a battery. This is the Krebs cycle. The electrochemical energy (in the form ATP) is then used for nerve signals and muscle movements and manufacturing biochemicals – everything for which the body requires energy. Classic MFRTA In the original version of MFRTA theory, there are unavoidable by-products of the highly-energetic chemical reactions that power our bodies. These are free radicals or ROS, and they corrode the body’s delicate chemistry. There are quencher chemicals – antioxidants that help mop up the toxic waste. These include SOD, ubiquinone (coQ10), and glutathione, catalase, and vitamin C. But they are not 100% efficient at preventing damage. It is the buildup of damaged biochemicals that is the root cause of aging. One of the attractive things about the MFRTA is its connection to evolutionary history. Once upon a time, more than a billion years ago, mitochondria were infectious bacteria. They invaded the primitive cells at the time, lived as parasites, and killed the cell with their powerful oxidative toxins. Over a long period of time, the parasites evolved to be friendlier to the host, and the host evolved to exploit the energy products of the parasite. Every eukaryotic cell, including all multi-cellular life today, is descended from this ancient symbiosis. Modern mitochondria are performing in the service of the host cell, and have no will of their own. But they retain the capacity to kill the cell, and in fact can serve as executioners when they are signaled to do so. This is apoptosis, or programmed cell death. Problems with the MFRTA theory include: Anti-oxidants don’t seem to extend life span when fed

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### 方法2：pandas.Series.shift\n", "\n", "shift用于移动数据，但是保持索引不变\n", "\n", "官方文档地址：https://pandas.pydata.org/pandas-docs/stable/reference/api/pandas.Series.shift.html" ] }, { "cell_type": "code", "execution_count": 14, "metadata": {}, "outputs": [ { "data": { "text/html": [ "<div>\n", "<style scoped>\n", " .dataframe tbody tr th:only-of-type {\n", " vertical-align: middle;\n", " }\n", "\n", " .dataframe tbody tr th {\n", " vertical-align: top;\n", " }\n", "\n", " .dataframe thead th {\n", " text-align: right;\n", " }\n", "</style>\n", "<table border=\"1\" class=\"dataframe\">\n", " <thead>\n", " <tr style=\"text-align: right;\">\n", " <th></th>\n", " <th>bWendu</th>\n", " <th>bWendu</th>\n", " <th>bWendu</th>\n", " </tr>\n", " <tr>\n", " <th>ymd</th>\n", " <th></th>\n", " <th></th>\n", " <th></th>\n", " </tr>\n", " </thead>\n", " <tbody>\n", " <tr>\n", " <td>2017-01-31</td>\n", " <td>3.322581</td>\n", " <td>NaN</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-02-28</td>\n", " <td>7.642857</td>\n", " <td>3.322581</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-03-31</td>\n", " <td>14.129032</td>\n", " <td>7.642857</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-04-30</td>\n", " <td>23.700000</td>\n", " <td>14.129032</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-05-31</td>\n", " <td>29.774194</td>\n", " <td>23.700000</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-06-30</td>\n", " <td>30.966667</td>\n", " <td>29.774194</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-07-31</td>\n", " <td>31.612903</td>\n", " <td>30.966667</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-08-31</td>\n", " <td>30.129032</td>\n", " <td>31.612903</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-09-30</td>\n", " <td>27.866667</td>\n", " <td>30.129032</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-10-31</td>\n", " <td>17.225806</td>\n", " <td>27.866667</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-11-30</td>\n", " <td>9.566667</td>\n", " <td>17.225806</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2017-12-31</td>\n", " <td>4.483871</td>\n", " <td>9.566667</td>\n", " <td>NaN</td>\n", " </tr>\n", " <tr>\n", " <td>2018-01-31</td>\n", " <td>1.322581</td>\n", " <td>4.483871</td>\n", " <td>3.322581</td>\n", " </tr>\n", " <tr>\n", " <td>2018-02-28</td>\n", " <td>4.892857</td>\n", " <td>1.322581</td>\n", " <td>7.642857</td>\n", " </tr>\n", " <tr>\n", " <td>2018-03-31</td>\n", " <td>14.129032</td>\n", " <td>4.892857</td>\n", " <td>14.129032</td>\n", " </tr>\n", " </tbody>\n", "</table>\n", "</div>" ], "text/plain": [ " bWendu bWendu bWendu\n", "ymd \n", "2017-01-31 3.322581 NaN NaN\n", "2017-02-28 7.642857 3.322581 NaN\n", "2017-03-31 14.129032 7.642857 NaN\n", "2017-04-30 23.700000 14.129032 NaN\n", "2017-05-31 29.774194 23.700000 NaN\n", "2017-06-30 30.966667 29.774194 NaN\n", "2017-07-31 31.612903 30.966667 NaN\n", "2017-08-31 30.129032 31.612903 NaN\n", "2017-09-30 27.866667 30.129032 NaN\n", "2017-10-31 17.225806 27.866667 NaN\n", "2017-11-30 9.566667 17.225806 NaN\n", "2017-

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though, once the Russians attacked with masses of wide-tracked T-34 tanks backed by hordes of Siberian infantry dressed in warm winter uniforms. Hitler ordered troops to stay in place, regardless of the cost, to prevent a rout. That saved the German army, but it would never get that close to Moscow again. ## Mother Russia Is a Cruel Mistress Invading Russia has never been a good idea, historically. France's Napoleon and Sweden's Charles XII failed miserably, losing their armies. Like his predecessors, Hitler was made overconfident by early victories. The easier alternative is not invading. It is doubtful this would have been a sound strategy. Soviet dictator Joseph Stalin still allowed his staff to plan a possible attack on German-held Poland in the spring of 1942. Such a move was improbable, but not impossible. Focusing on the German invasion itself, we can see that there were things that could have been done differently to better prepare for the campaign. Germany could have put more effort into expanding its auto industry, adding more trucks to its motor pool. Or it could have improved its rail capabilities, making them able to convert track from Russian to German gauge at a faster clip. Operationally, Germany's generals could have narrowed the plan. As originally written, three army groups would have had to take Leningrad, Moscow, Ukraine, Crimea, and the Caucasus, all in one campaign season! And solidify their gains before the winter weather arrived! Planners could not seem to limit their goals to the attainable. While the German army captured some strategic objectives, German strength was stretched too thin in the attempt to take all of them. Perhaps a better move was to forgo Leningrad and concentrate on Moscow and Ukraine. Or fight a slower campaign, moving all three army groups east by three hundred miles, stopping, then riding out the winter while managing a strained, but shorter supply line. The lull would have allowed rail lines to be converted to German gauge for their entire length; then the supply dumps could have been rebuilt. By gambling, Hitler came within twenty miles of taking Moscow. Being less ambitious he could have reaped Moscow as the prize in 1942, avoiding Stalingrad and an overstretched campaign in the Caucasus. This would have been inconsistent with the way Germans fought their wars, favoring the attack and quick pursuit over deliberate advance and supply. German determination and improvisation can only take an army so far when supplies are lacking. # 62 # RONALD REAGAN STARS IN CASABLANCA 1942 By Mike Resnick What if this actor had not played on the world stage? The unproduced play was titled _Everyone_ _Comes to Rick's._ After it failed to find a Broadway producer, it was submitted to Hollywood, where story editor Irene Diamond read it, thought it had possibilities, and recommended that Hal B. Wallis purchase the film rights, which he did for a less-than-munificent $20,000. The title was changed to _Casablanca_ , where the action took place. It starred Humphrey Bogart and Ingrid Bergman, it featured Claude Rains and Paul Henreid, and it had a delicious supporting cast that included Peter Lorre, Sydney Greenstreet, Conrad Veidt, S. Z. Sakall, and Leonid Kinskey. It was rewritten on an almost day-by-day basis by the team of Julius and Philip Epstein, with some additional help from Howard E. Koch, and directed by Michael Curtiz. The film was originally scheduled for release in mid-1943, but it was rushed into distribution, with a world premiere on November 26, 1942, and an official release date of January 23, 1943, to capitalize on the Allies' landing in North Africa. No one at Warner Bros. expected it to do much at the box office or in the awards, which just goes to show how incredibly wrong people can be. _Casablanca_ won the Academy Award for Best Picture, became an instant classic, and has always ranked among the top two or three films every time the American Film Institute ranks its top one hundred films. It made five-foot-seven-inch balding Bogart a romantic lead, as well as the most popular actor in America. Okay, that's what happened. But what might have happened is just as interesting. Humphrey Bogart was not the first actor considered for the role of Rick Blaine. Jack Warner wanted George Raft or James Cagney, and after all, Bogart had only one big hit behind him—the recent _Maltese Falcon—_ and he had never played a romantic lead. But before they signed Bogart, they had in mind yet another Warner's contract player. There's every chance you may have heard of him. On January 7, 1942, Warner Bros.'s Hollywood News Press Service released the following statement: "Ann Sheridan and Ronald Reagan will be teamed by Warner Brothers for the third time in _Casablanca._ " Nothing came of it. But what if Reagan _had_ wound up with the role of Rick Blaine? Yes, he was in the army by then . . . but what if they'd held the movie for him? After all, not a single theatrical producer had been willing to put it onstage, and Bogart's name wasn't yet box office magic. What if the film, made in 1945, was every bit as popular with him in the lead as it was with Bogart? What logically follows? Well, for starters, Reagan moves up the ladder to become Warner's number one romantic lead. But the wild popularity of _Casablanca_ has created a huge demand for his screen services, and he finds himself overwhelmed with offers. His next appearance is the lead in _To Have and Have Not_ , a role that would have gone to Bogart had Reagan not established himself as a romantic star in _Casablanca._ The film is a hit, and suddenly Reagan has his choice of plum roles, roles that would never have been offered to him had _Kings Row_ been the apex of his acting career. He beats out Gregory Peck for the lead in _Gentleman's Agreement_ , actually wins an Oscar after beating relatively unknown Ernest Borgnine for _Marty_ , makes thirty-five films—most of them big-budget, highly publicized ones—between 1946 and his retirement (after starring in his final film, a television remake of _The Last Hurrah_ ) in 1977 _._ At one time, during the war, he thought of working for the Screen Actors Guild when he came home, perhaps even running for an office within the guild. But when he received literally two million accumulated fan letters and fourteen bona fide movie offers, he realized that he couldn't possibly take the time, at least not until he took some of these very choice acting jobs and put some money in the bank. But of course, the more he performed, the more offers came his way, and the more the industry depended on him to keep performing, and he finally realized that no, he was not going to run for president (or any other office) of the Screen Actors Guild. It was two decades later that the policies of Governor Pat Brown and other Democrats so outraged him that for the first time in his life he registered as a Republican. He was working constantly, as he had been since 1945, but he donated some $3 million to Republicans in state and national races. It would be nice to say that he and Bogart traded places, but Bogart was an on-and-off liberal, and his chain-smoking caused his death in January of 1957. So what _did_ happen during the years that Reagan, under different circumstances, might have run for president, not of the Screen Actors Guild, but of the United States of America? Well, there was quite a battle among Republicans, but George H. W. Bush emerged with the 1980 nomination, and beating Jimmy Carter when Iran was holding dozens of hostages and the prime rate topped 21 percent was even easier than it had looked, with the seated president winning only ten states. Bush didn't scare the Ayatollah Khomeini the way a President Reagan would have, and in 1982, the United States invaded Iran, freeing all but five of the hostages (who were killed during the action) and replacing Khomeini with a pro-democracy, pro-America ruler. Bush did not preside over the phenomenal economic recovery and job growth that Reagan would have brought about, but compared to the economy he inherited, he was soon labeled an economic wizard, and of course he won reelection in 1984. It was said that he relaxed from the heavy pressures of his office by watching endless reruns of _Casablanca._ # 63 # KURSK 1943 By Harry Turtledove "My stomach turns over." After Field Marshal Friedrich Paulus surrendered the last ninety thousand starving, freezing Germans in Stalingrad at the end of January 1943, anyone with eyes to see should have understood that Hitler would never beat Stalin on the Eastern Front. (Paulus was promoted to field marshal just before the surrender, to persuade him to shoot himself instead of giving up—no German field marshal had ever surrendered. It didn't work. Only about five thousand of those Germans ever saw the Vaterland again. He was one of them.) As the winter of 1942–1943 wore on, what wasn't obvious was whether the entire German position in the southern USSR would go to

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feel yourself completely suspended in the universe. You actually feel like you are in space and moving with the organic movements of the universe. The lightness is where I’m no longer in the matrix with you. You’re talking and I’m so free in this entire universe that I can feel the universe and my suspended state. You can feel the current, the neural pathways in your brain in the opposite hemisphere that begins to wake up, that says: oh, oh, I’m God; yes, I’m God. I’m not my emotions or defined by them. You’re introducing two things to the frontal lobe – vibration and light. The frontal lobe is meant to repeat the name of God. That’s what it’s designed for. The frontal lobe is there to keep us constantly in that current of vibration. If you could sustain your lightness and luminosity, the entire matrix of your being will rearrange itself. So when I say to you: if you can feel that currency and really be aware of that and the light at the same time, within three months you’re going to be so grateful to be alive that you’re ready to explode. You’re so grateful that every moment and every cell within your body belongs to the universe. Throughout your whole year, if you truly become grateful, and truly allow – I don’t care if somebody cuts you off, you can go: you stupid bugger. But if you engage into the action, you’ve just created another mirror of reflection that sits in your future. We are at an intensified period of time when if you become grateful, even if you simply say: I hate my job! Be grateful; because that will get you another job. But the more you loathe your job, the deeper you’re going to sink. The more grateful you are for everything, the more you will get uplifted. Whatever you think you are in charge of, just realize you’re in charge of nothing! Zero! This is a time where you might think you can think your way out of it and you cannot. But you can lift your way out of it. You need to fly. And if you fly throughout this entire year, you’ll pull yourself predominantly out of this matrix because energetically this is what the universe is all about. Let this whole personality identity step aside and really TRUST big time. Say: I’m going to be fine. It’s going to be good. God loves me. God knows where I am. God has my address. God has my email address. God has my phone number. I am in his directory. He knows who I am; knows where I live. The reality: that is that shift in the lightness. God knows every moment, every second, every burp, every fart, every moment, God knows. You are so much more than who you are today. This blog is an excerpt from the Pathway to Consciousness event in January 2017 in Toronto, Canada. ]]>[email protected] (Bart Smit)BlogWed, 31 May 2017 01:00:00 +0000Trump and the January 2017 Women's March - The currency of Freedom!https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/66-trump-and-the-january-2017-women-march https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/66-trump-and-the-january-2017-women-march You know it’s going to be loud and noisy. But it’s all right; it’s what needs to happen. Women are extraordinary when it comes to change. Are women uniting humanity? Absolutely. Women are the ones who give birth to children. They create the next generation. That many women who demonstrated without someone like Trump stopping it or trying to do a curfew – for that to have happened is extraordinary. That demonstration is the beginning of the wave that will create change in the world. Imagine there are reptilian races all fighting for power. Do I think this is a good thing? Absolutely. Kill each other. Knock yourselves out. Let the world wake up to recognizing that this kind of behavior that has existed for centuries….Donald Trump and someone like Hitler – there is no difference. They’re exactly the same. One had the ability to kill people and the other is in the process of creating chaos. He is using the same methodology of creating fear. Exactly what Hitler did. But the world didn’t stop Hitler. So, do I think this is a massive opportunity for Consciousness to rise? Absolutely. When you listen to someone like Trump and what he does, if you have great faith in the universe, he will last one day less. The more you judge him, the more you observe and absorb, process, and have an opinion, the longer he stays in power. Why does your boss at work have power? Because you gave him power. Why does anybody have power? Because you gave it to them. So, people rise to power because you say: oh my goodness, I’m supposed to listen to Donald Trump…the more the world stops paying attention, the more the universe goes – Baby! Love. There’s something bigger. The moment you believe that there’s a greater power, a greater purpose for all of this, the less he will be in office. That’s what this is about. We don’t focus on Donald Trump, we focus on YOUR awakening. When you become pure light and currency and you affect the next person and the next person, he comes out of power. It’s about YOUR awakening. It’s all the Atlanteans who are rising and awakening. Imagine this is all a currency war. I’m talking about currency of the heart. And currency in here and currency out here are the same thing. The more you can have currency in here, the richer and happier you become. It’s all currency – of love, compassion, empathy. But if you look at what’s happening out here, it’s a currency war. What happened with all those people on that huge walk – they were not afraid. Their brains lit up differently. They were not coming together in anger or hatred; they came in love; love that echoed through every currency of the universe. And it is THIS that creates transformation. All those women having their demonstration, that was the largest percent of Atlanteans gathered at one time. Not everyone, but the majority who traveled were all Atlantean women. They are healers. They heal pain. They don’t buy into pain. They HEAL pain. Atlantean women don’t buy into anger; they transcend it. Atlantean women don’t buy into fear; they heal. They don’t buy into what’s in front of them. They see the desperation. We don’t buy into desperation, we rise above it. This is a currency war, but also a war between reptiles. All the reptiles are going after each other, where before they all went after YOU. Now they’re going after each other. For where we are: AMEN! HALLELJUAH! Knock each other out and let all these Atlantean men and women LET THEM RISE and create the change so these types of reptiles will NEVER be in power again. HUGE!!! HUGE!!! HUGE!!!! This has NEVER been possible in 2K years. All of this is currency, currency of love and energy; the currency of FREEDOM! This blog is an excerpt from the Pathway to Consciousness event in January 2017. The next Pathway to Consciousness event will be in Toronto in the Fall 2017. Bart Smit's next public event scheduled will be at the Akasha's Den June 3, 2017. Bart will be channeling Dr. Williams. ]]>[email protected] (Bart Smit)BlogTue, 18 Apr 2017 11:37:00 +0000I am not here to be the pain of myself or the pain of the world.https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/65-i-am-not-here-to-be-the-pain-of-myself-or-the-pain-of-the-world https://bart-smit.com/index.php/support-material/bartsmitblogfile/item/65-i-am-not-here-to-be-the-pain-of-myself-or-the-pain-of-the-world As we’re moving into a new world’s economy, and the United States is going through it’s own battles, this is not a time to process through your lower chakras or other people’s needs or emotions or to let these lower chakras be stimulated. This is the time for you to hold your heart, the part of this quadrant and the reptilian brain and frontal lobe in such silence and stillness because this is how the world gets lifted to great Consciousness. To help us achieve this, Dr. Williams has given us a prayer: I’m here to experience liberation. I am not here to process everyone else’s needs or emotions. I’m not a slave to my emotions or anyone else’s. I’m here for liberation. I’m here to be awakened. I am not here for my lower chakras

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does not enter a second-order perturbative analysis. Figure from Ref.[@Vary:2009gt].[]{data-label="n_odd"}](n_odd.eps){width="8cm"} To date, we have found no matrix element trends with increasing transverse energy that would imply new divergences. All such matrix elements sets we examined, within a perturbative analysis, fall faster than $1/\sqrt{n'}$. Also, we found no sets that remained constant with increasing $m'$ (and thus $m$) holding $n,n'$ fixed. As a result of this initial analysis, we anticipate that straightforward adoption of counterterm methods previously introduced [@JPV214] will be sufficient for managing the identified divergences in BLFQ. As another example of the interacting cavity mode QED, we present in Fig.\[eigenvalues\_4x4.eps\] the eigenvalue spectra for a Hamiltonian matrix that includes lepton and lepton-photon Fock spaces. The leptons are now massive with $\bar m_l=0.511$ MeV, and the HO parameters are $\Omega=0.1$ MeV and $M_0=\bar m_l$. The other basis parameters are chosen as $K=3$, $N_{max}=2$ and $M_j=1/2$. The eigenvalues are shown as a function of the strength of the coupling with respect to the coupling at QED, with $g_{\rm QED}=\sqrt{4\pi\alpha}$. Since the instantaneous fermion interaction term only contributes when all the leptons and photons of the process have their spins aligned, this particular case only involves the photon emission vertex interaction (see e.g. Ref.[@Anommm]). Application of the sector-dependent renormalization [@Karmanov] will shift these eigenvalues such that the lowest one will obtain the value $E_0=\frac{\bar m^2+M_0\Omega}{K}$, where $\bar m$ is the mass of the lowest state fermion. As we increase the cutoffs $K,N_{max}$, the evaluation of the electron anomalous magnetic moment will serve as an important precision test for our method [@Anommm]. ![ Eigenvalues of a cavity mode QED Hamiltonian, which includes lepton and lepton-photon Fock spaces, as a function of the strength of the coupling ($g_{\rm QED}=\sqrt{4\pi\alpha}$). The HO parameters are $\Omega=0.1$ MeV and $M_0=0.511$ MeV, and the other basis parameters are $K=3$, $N_{max}=2$ and $M_j=1/2$.[]{data-label="eigenvalues_4x4.eps"}](eigenvalues_4x4.eps){width="9cm"} Conclusions =========== Following successful methods of [*ab initio*]{} nuclear many-body theory, we have introduced a basis light-front quantization (BLFQ) approach to Hamiltonian quantum field theory. With a cavity mode treatment of massless non-interacting QED we showed how the number of many-parton basis states exhibit a dramatic rise as the cutoffs are elevated. 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4). Let m = 0.1 - 0.9. Let w = m - -0.9. What is the nearest to w in 0.2, 5, x? 0.2 Let y = -65 + 62. Which is the closest to -6? (a) 4 (b) 5 (c) y c Let i be ((-4)/3)/(8 - (-396)/(-45)). Let f = 0.1 - 2.1. Which is the closest to f? (a) -0.3 (b) i (c) -3 c Suppose -4*y - 110 = 2*g, -5*y - 145 = -g + 5*g. Let q = 15 + y. Let v be q/6 + 2/1. Which is the closest to -0.1? (a) 1/4 (b) 3 (c) v a Let m(k) = k**3 + 7*k**2 + 10*k + 3. Let g be m(-5). Let z = -6 - 40. Let s be (-2)/(z/25) - 1. Which is the nearest to g? (a) s (b) 0.4 (c) -3 b Let z be 4 + (2 - 35/6). Which is the nearest to -2/7? (a) z (b) -1/3 (c) -3/8 b Let v be ((-2)/6)/((-2)/4). Let z = -3.6 + 3. Let i = z - -5.6. What is the nearest to 1 in i, 4, v? v Let h = 3 + -3.1. Let q = -2.6 - -3. Let k = q - 0.9. Which is the nearest to 2/7? (a) -3/7 (b) h (c) k b Let q = 2 - 3. Let k be (35/(-70))/(14/(-8)). What is the closest to 0.1 in q, k, -0.1? k Let r = -40 - -40. Suppose -j + 8 - 3 = 0. What is the closest to -1 in -3, r, j? r Suppose -4*c + 3 = -1. Let o = 115 - 107.9. Let h = o + -7. What is the closest to c in 0.5, 0.3, h? 0.5 Let i = 351524 + -3875834/11. Let k = 820 + i. Let t = k - -389/88. Which is the nearest to -1/3? (a) t (b) -0.2 (c) -5 b Let v = -57/2 + 29. Which is the nearest to 0.1? (a) -5/3 (b) -3 (c) v c Let l be 9/(-3) + (30/9 - 0). What is the nearest to -0.9 in l, -0.1, 0.2? -0.1 Let r = 6 - 11. Which is the closest to 2? (a) r (b) 0.4 (c) -2/9 b Let g = 2.2 + -2. Let y be 7/(-12) + (-2)/(-8). Let c = -92 - -88. What is the nearest to y in c, -0.4, g? -0.4 Let i = 24 - 25.7. Let f = i + 2. Let w = 0.5 + -1. Which is the closest to 0? (a) f (b) w (c) -0.4 a Let p = 0.1 + 0.4. Let l = p + -0.3. Let r = l - 0.1. Which is the nearest to r? (a) 0.1 (b) 2 (c) -3 a Let n = 4 + -4.6. Let u = -0.4 - n. Which is the closest to -3? (a) u (b) 3 (c) 4 a Let j = 0.2 - 0.7. Let m = j - -3.5. Let l = -13/115 - 2/23. Which is the nearest to 0.1? (a) m (b) 0.5 (c) l c Let r(z) = z - 12. Let h be r(12). Suppose 11 = -4*x - x + 2*g, 15 = -3*x - 3*g. Which is the nearest to h? (a) x (b) 0.2 (c) -0.4 b Let p = 1.7 + -2.6. Let q = p + -0.1. Let h = -1/76 - -155/228. What is the closest to h in -3, q, 0.3? 0.3 Let f = -6 + 6.6. Let p = f - 0.6. Let l = -1006/33 - -92/3. What is the nearest to p in 0.1, -3/7, l? 0.1 Suppose -2*m + 7*m = -10. What is the nearest to 0.1 in -0.5, -1/11, m? -1/11 Let h = 22.1 + -22. Let p be 1 + -3 + 0 - -7. What is the nearest to h in -4, p, 0.4? 0.4 Let u = -1.1 - -0.1. Let j = 5.84 + 0.16. Let z = j + -5.5. Which is the closest to u? (a) z (b) -1/3 (c) 1 b Let m be 15/50*5/(-2). Let i be (1/5)/((-4)/(Background The six-carbon circular non-proteinogenic compound l-pipecolic acid is an important chiral drug intermediate with many applications in the pharmaceutical industry. In the present study, we developed a metabolically engineered strain of Escherichia coli for the overproduction of l-pipecolic acid from glucose. Results The metabolic pathway from l-lysine to l-pipecolic acid was constructed initially by introducing lysine cyclodeaminase (LCD). Next, l-lysine metabolic flux from glucose was amplified by the plasmid-based overexpression of dapA, lysC, and lysA under the control of the strong trc promoter to increase the biosynthetic pool of the precursor l-lysine. Additionally, since the catalytic efficiency of the key enzyme LCD is limited by the cofactor NAD+, the intracellular pyridine nucleotide concentration was rebalanced by expressing the pntAB gene encoding the transhydrogenase, which elevated the proportion of LCD with bound NAD+ and enhanced l-pipecolic acid production significantly. Further, optimization of Fe2+ and surfactant in the fermentation process resulted in 5.33 g/L l-pipecolic acid, with a yield of 0.13 g/g of glucose via fed-batch cultivation. Conclusions We expanded the metabolic pathway for the synthesis of the chiral pharmaceutical intermediate l-pipecolic acid in E. coli. Using the engineered E. coli, a fast and efficient fermentative production of l-pipecolic acid was achieved. This strategy could be applied to the biosynthesis of other commercially and industrially important chiral compounds containing piperidine rings. Chirality plays a key role not only in the life of plants and animals but also in the pharmaceutical, agricultural and chemical industries [1, 2]. Particularly, in the pharmaceutical industry, 56% of all drugs currently in use are chiral and screening and production of single enantiomers of chiral intermediates is increasingly important [3]. l-pipecolic acid (l-PA) is a non-proteinogenic compound and key chiral intermediate in the synthesis of many important groups of drugs [4] (Fig. 1). l-PA with a high optical purity is a precursor for the anaesthetics ropivacaine, bupivacaine and chloroprocaine which are widely used in local anaesthesia [5]; and it is also a precursor for the macrolide-pipecolate immunosuppressor rapamycin, FK-506 and FK-520 that are indispensable in the clinic [6]. Similar to the preparation of most of the other enantiomeric organic compounds, pure l-pipecolic acid enantiomers are mainly produced by chemical enantioselective synthesis [7] and stereoselective transformation [8]. However, the chemical methods for commercial-scale preparation of l-PA are complex and environmentally unfriendly [9]. Total biosynthesis of chiral drug intermediates is a more environmentally friendly approach for the preparation of affordable pharmaceuticals [10]. Bioproduction of l-PA has been extensively investigated, mainly due to its close relationship with l-lysine metabolism [11, 12]. Previous studies [11–13] have established two basic routes for converting l-lysine to l-PA. The first involves the loss of the α

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-type="fig"}, and the rotated angle *θ* and ${A_{x}}^{\prime} = \sqrt{A_{x}^{2} + A_{y}^{2}}$ are accrued. Phase II, as shown in [Figure 3(b)](#fig3){ref-type="fig"}, is to rotate the $\overset{⃑}{g^{\prime}}$ vector on the *x*-*z* plane and have it aligned to the *x*-axis, as looking from the pointing direction of the *y*-axis (right side). The rotation is performed by 2D CORDIC on the *x*-*z* plane with the initial 2D vector (*A*~*x*~′, *A*~*z*~) and have it aligned to the *x*-axis. The iterative equations are shown in [Figure 3(b)](#fig3){ref-type="fig"}, and the rotated angle *δ* is accrued through CORDIC operations and *φ* = *π*/2 − *δ*. As you can see, the tilt angle, *φ*, is obtained with simple shifting and addition operations only by this proposed algorithm. 2.4. System Design and Realization {#sec2.4} ---------------------------------- ### 2.4.1. Definition of Head Position Angles {#sec2.4.1} In the proposed sensing system, an accelerometer is attached to the forehead of the subject mounted with 3M™ Micropore™ Surgical Tape in the orientation shown in [Figure 4(a)](#fig4){ref-type="fig"}, where *x*-axis points toward the head of the head, *y*-axis points to the right-hand side of the body, and *z*-axis points to the front of the head. With the accelerometer attached to the forehead to comply with the defined orientation, the head would rotate along the *x*-axis. Therefore, the rotation angle *θ* and the inclination angle *φ* can be calculated as in ([3](#EEq2){ref-type="disp-formula"}) for a different orientation compared with those in ([2](#EEq1){ref-type="disp-formula"}). It is also represented in [Figure 4(b)](#fig4){ref-type="fig"}. $$\begin{matrix} {\varphi = \arctan\left( \frac{A_{x}}{\sqrt{{A_{y}}^{2} + {A_{z}}^{2}}} \right),} \\ {\theta = \arctan\left( \frac{A_{y}}{A_{z}} \right) + \sigma \cdot \lambda \cdot \pi,} \\ \end{matrix}$$where *σ* = 0, if *A*~*z*~ ≥ 0; otherwise, *σ* = 1. *λ* = 1, if *A*~*y*~ ≥ 0; otherwise, *λ* = −1. ### 2.4.2. System Realization {#sec2.4.2} The overall system consists of front-end sensing subsystem and back-end data conversion subsystem. The front-end subsystem is the accelerometer sensor with a microcontroller for data acquisition and tilting angle transformation in digital formats. The angle information is then passed to the back-end subsystem for signal conversion into analog voltage signals to be hooked up with the PSG devices. Digital information has to be converted into analog signals because the tilting information has to be integrated with the PSG devices through their AUX inputs which are available for most of the PSG devices. Depending on how the data can be passed from front-end to back-end, the system can be realized as a wired system or a wireless system. ### 2.4.3. Wired Sensing System Implementation {#sec2.4.3} The wired system block diagram is shown in [Figure 5](#fig5){ref-type="fig"} and mainly consisted of a microcontroller unit (MCU; ADuC7020; Analog Devices Inc.) and accelerometer modules (ADXL345, Analog Devices Inc.). The system was integrated into the PSG (Alice 5; Philips Respironics Inc.) for in-line and real-time application. The firmware executed on the MCU was developed in C language under the software of uVision4 IDE. The MCU core clock was set at 10.44 MHz. The accelerometer module was an ultralow-power high-performance 3-axis digital accelerometer. It has the sensitivity of 3.9 mg/LSB with a ±2*g* range and an on-chip low-pass filter for the removal of high-frequency noise. The communication between the accelerometers and MCU was through an I2C bus on a wired cable. The sampling rate of the accelerometer was set to be 100 Hz, and therefore, the MCU received the rectangular coordination (*A*~*x*~, *A*~*y*~, and *A*~*z*~) of vector (−1*g*) from a 3-axis digital accelerometer for every 10 ms. The data were then transformed to the angular domain for tilting angle identifications. Four channels of on-chip digital-to-analog converters (DACs) were included in the MCU and converted the in-line calculated angles into analog voltages representing the inclination information. Then, the information was directly transferred to the auxiliary inputs of the PSG for the study of remission of the patient with OSAS. This is the system that has been implemented for the IRB tests. ### 2.4.4. Wireless Sensing System Implementation {#sec2.4.4} If the tilting information of the head is transmitted wirelessly to the back-end data conversion subsystem and hooked up to the PSG, then it is the wireless sensing system. With this implementation, a front-end sensing subsystem could be attached on the forehead of the subject and without any cable connected to the PSG. In this front-end sensing subsystem, a module named "*BASIC*" was developed. BASIC stands for BLE-enabled Accelerometer-based Sensing In a Chip-packaging and is a fusion of A, B, and C technologies which are the accelerometer-based inertial sensing, Bluetooth low-energy (BLE) technology, and CORDIC-based tilting angle transformation algorithm. It is an integration of the accelerometer with the BLE module with CORDIC-based tilting angle transformation algorithm realized in the SoC of the BLE module. So, the module is capable of transmitting the tilting information according to the configured orientation over the air wirelessly by itself. The photo of the BASIC module and its block diagram is shown in [Figure 6](#fig6){ref-type="fig"}. With this module attached to the forehead of the subject, there will be no wired connection from the sensing front-end to the data conversion back-end which is then attached to the PSG device. The back-end system can be simply modified from [Figure 5](#fig5){ref-type="fig"} using a BLE module to receive the transmitted data from the wireless sensing front-end subsystem, for example, the BASIC module; then, the received data are filled into the DACs inside the MCU for signal conversion and hooked up to the PSG device. 3. Results {#sec3} ========== In this section, the accuracy of the CORDIC-based tilting sensing algorithm-converted information is analyzed by comparing the angle calculated using mathematical equations as in ([3](#EEq2){ref-type="disp-formula"}). Then, the accuracy of the proposed sensing system was tested with a three-axis rotation platform to measure its actual accuracy under a precise controlled environment. Finally, the results of the system applied in a clinical IRB test is shown to prove the usability of the system for an unmet medical need. 3.1. Precision of the CORDIC-Based Tilting Sensing Algorithm {#sec3.1} ------------------------------------------------------------ Validation of the algorithm accuracy was performed to show its precision. The number of iterations executed in the CORDIC-based algorithm can greatly impact the accuracy. Generally, the more iterations executed, the better accuracy can be obtained. But, the trade-off is to increase the computation time. An optimization was performed to find the number of iteration with acceptable accuracy and computation time. Hereby, different numbers of iterations from 4 to 12 were tested and compared with those of the calculated angles from the offline mathematical calculations. The results are summarized in [Figure 7](#fig7){ref-type="fig"}. It indicated that to meet the medical requirement of accuracy at 1°\~2°, an acceptable accuracy of ±0.8 degrees for rotation angles and ±0.49 degrees for inclination angle was calculated by 8 iterations with the computation time of 795.9 ms. Such computation time was still much faster than the one from the original trigonometric calculation. 3.2. Accuracy of the Sensing System with an Accelerometer {#sec3.2} --------------------------------------------------------- The accuracy of the sensing system with the actual accelerometer was confirmed through testing on a controllable three-axis rotation platform (with a tri-axis step motor controller, TL-3T, from Tanlian E-O Co. Ltd.), as shown in [Figure 8(a)](#fig8){ref-type="fig"}. The accelerometer sensing module being tested was placed at the center of the platform. During such testing, the tilting angles of the platform are controlled using precise step motors on the *x*-axis, *y*-axis, and *z*-axis with a resolution of 0.0025 degrees per step. In addition, the tilting angle of the

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with a dermatitis condition that clears up if he avoids certain agents, receives a zero percent impairment even if that person cannot return to the type of employment that he was performing at the time of his exposure and outbreak (this is the example that applies to the claimant herein). However, under "Class two, 10% to 20%, Example one", Page 145, a housewife that develops a chronic dermatitis that requires some intermittent treatment receives a ten percent impairment. Thus, it is obvious that the effect that the skin condition has upon one's economic loss, which is the heart of the wage loss concept, is not a factor in making a determination of impairment to the skin under the Guides. Collaterally, but not a factor in the undersigned's findings, is the pronouncement in Trindade, supra, that since the indispensable requisite of the wage loss concept is economic *950 loss, a classification which distinguishes between eligible and ineligible claimants on a basis which bears no reasonable relationship to their respective economic loss is violative of certain Federal and State Constitutional guarantees. The claimant's physician has opined that the claimant would have a permanent impairment as a result of his condition if he continued to work with wet cement. However, the claimant would encounter increasing physical problems from the dermatitis that would eventually totally incapacitate him from working in that employment. Additionally, the employer/carrier could assert the affirmative defense of a voluntarily inflicted injury against claims for indemnity benefits under those circumstances. Accord: Ernest Waters Construction Company v. Mills, 51 So.2d 180 (Fla. 1951). On the other hand, if one accepts the premise that the Guides are exclusive in this particular situation, and the claimant accepts other less remunerative employment, he would not be entitled to wage loss benefits because the Guides do not provide an impairment rating. I find, however, that under the facts of this particular case, the Guides do not deal with the effect that the dermatitis has upon the claimant's ability to return to and perform the various physical activities of the employment in which he developed the occupational disease as opposed to the claimant's ability to carry out daily living activities as defined by the Guides. The claimant's treating physician, Harold Seder, M.D., a Board Certified Dermatologist, has opined that the claimant would have a permanent impairment if the claimant continued to work with wet cement and that he would eventually become totally disabled from working in that employment as a result of the dermatitis. Dr. Seder also observed the outbreak of the dermatitis upon the claimant's skin. It was Dr. Seder's opinion that the claimant should not return to employment involving contact with wet cement. The undersigned accepts the testimony of Dr. Seder and finds that this expert opinion is competent and substantial evidence that establishes the existence of a permanent impairment of an unknown degree under the facts of this particular case and that this evidence meets generally acceptable medical standards for determining impairment, especially in light of the fact that the doctor was not aware of any guides other than the A.M.A. Guides for determining dermatological impairment. Claimant clearly suffers from permanent impairment which has resulted in his "incapacity because of the injury to earn in the same or any other employment the wages which the employee was receiving at the time of the injury." (emphasis added). Section 440.02(9), Florida Statutes. Due to his skin condition, claimant cannot work in his chosen occupation, where he earned a relatively high salary, and, in all likelihood, is unable to earn an equal wage in other employment without further training. Although not presented as an issue, we note that neither the employer nor its servicing agent has provided claimant any rehabilitation services as required by Section 440.49(1)(a), Florida Statutes.[1] In the *951 situation before us, claimant's condition is directly related to his occupation. Under the terms of the Guides, there is no impairment if the injury does not affect the employee's daily living. In the case sub judice, claimant's skin condition does not affect his daily living as long as he does not work in his job. Essentially, as long as claimant does nothing, there is no impairment. In Trindade v. Abbey Road Beef 'n Booze, 443 So.2d 1007, 1011 (Fla. 1st DCA 1983), this court held: We have the obligation of interpreting a statute in a manner consistent with the legislative intent, to the extent it is ascertainable and can lawfully be implemented. We have the further obligation of applying an interpretation upholding the constitutionality of a statute, if such an interpretation is permissible. Department of Insurance, State of Florida v. Southeast Volusia Hospital District, 438 So.2d 815 (Fla. 1983). Accordingly, although the Guides do not award the permanent impairment to claimant's skin condition, we affirm and agree with the deputy that, under the particular factual circumstances at bar, the Guides are not exclusively controlling because the Guides do not address claimant's evident economic loss, which is the basis of the wage-loss concept. Trindade at 1012. As to the award of temporary partial disability benefits, the deputy's finding that claimant conducted a valid, good-faith job search after his release by his doctor to return to some other type of employment is supported by competent, substantial evidence. We therefore affirm that award. We certify to the Supreme Court of Florida the following question as one of great public importance: DO THE AMA GUIDES TO THE EVALUATION OF PERMANENT IMPAIRMENT APPLY AND PRECLUDE A PERMANENT IMPAIRMENT RATING WHERE CLAIMANT SUFFERS A DISABILITY DUE TO OCCUPATIONAL DISEASE WHICH PERMANENTLY IMPAIRS CLAIMANT'S ABILITY TO WORK, RESULTING IN ECONOMIC LOSS, BUT DOES NOT AFFECT "THE ACTIVITIES OF DAILY LIVING?" WIGGINTON and BARFIELD, JJ., Concur. NOTES [1] Section 440.49(1)(a), Florida Statutes, provides, in pertinent part, as follows: (1) REHABILITATION OF INJURED EMPLOYEES. (a) When an employee has suffered an injury covered by this chapter and it appears that the injury will preclude the employee from earning wages equal to wages earned prior to the injury, the employee shall be entitled to prompt rehabilitation services. The employer or carrier, at its own expense, shall provide such injured employee with appropriate training and education for suitable gainful employment and may cooperate with federal and state agencies for vocational education and with any public or private agency cooperating with such federal and state agencies in the vocational rehabilitation of such injured employees. For purposes of this section only, "suitable gainful employment" means employment or self-employment which is reasonably attainable in light of the individual's age, education, previous occupation, and injury and which offers an opportunity to restore the individual as soon as practicable and as nearly as possible to his average weekly earnings at the time of injury... . You can try these similar gifts instead. Vintage Personalized Beer Pong Specialist Bar and Pub Sign He knows just how he wants to spend a lazy Saturday. Invite his friends over and organize a beer pong tournament. Who will be champion? There's no doubt about it, he's the best. It's sign for a guy who has the skills. This product is no longer listed on FindGift.com by this retailer. Check the Similar Gifts section above to find other gifts that may be suitable.Q: Is it safe to set Lua Table data from multiple C++ threads? As the title states. I'm curious if it's safe to set data in different Lua tables that exist in the same lua state. From multiple C++ threads. I'm asking this because my current system actually has a separating between Lua's data, and C++'s data, with Lua driving the majority of the game's update and loop - and C++ handling lower level details such as math, rendering, resources, and physics. After the physics update, I have to waste time in having an entire phase for Lua to update it's own internals for Serialization and grabbing references. A: No, Lua's state is not really thread-safe by default, so you can't access the same state from many threads without work on your part. Lua will call lua_lock and lua_unlock at appropriate points, but by default these methods do nothing and you must #define them to implementations that actually take the appropriate platform-specific critical section. However, that implements the most bare-bones approach to thread synchronization which just makes sure only one thread is running Lua at a time. You can see here for more information. A better approach might be trying to reorganize your update loop so something else can happen concurrently with the Lua state sync, which only itself happens on one thread. Perhaps after physics is done processing, you can both synchronize Lua and prepare your graphics calls at the same time? Or something similar; it's admittedly hard to say without knowing more about your architecture. Butyrate and acetyl-carnitine inhibit the cytogenetic expression of the fragile X in vitro. Cytogenetic expression of the fragile site at Xq27.3 is only found in those patients who have a full mutation of the FMR1 gene, i.e., a large amplification of the CGG repeat. However, an expansion of this repeat, although necessary, does not seem to be sufficient to cause expression of fra(X)(q27.3). Other factors are clearly needed, e.g., thymidylate

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We assessed patients using the respiratory disturbance index (RDI), the Epworth sleepiness scale (ESS), body mass index (BMI), fasting serum total cholesterol, triglycerides (TGs), and C-reactive protein (CRP). Mean RDI scores were 0.53, 10.6, 27.3, and 45.1 in the control group (n = 21), mild (n = 29), moderate (n = 31), and severe (n = 27), respectively. Partial correlation analysis showed that patients' RDI score was significantly correlated with CRP after adjustment for BMI. Partial correlation analysis showed that the mean ESS score correlated significantly with the CRP level after adjustment for BMI. Partial correlation analysis showed that the mean least oxygen saturation was significantly correlated with CRP after adjustment for BMI Pearson's correlation coefficients examining the relationship between BMI and total cholesterol; TG and CRP were found to be 0.531, 0.401, and 0.321. The correlation of CRP levels with disease severity as assessed by RDI, ESS, and least oxygen saturation was significant after adjustment for BMI. Patients with OSA have elevated serum levels of high-sensitivity-CRP, a marker for inflammation and an independent risk predictor for cardiovascular morbidity.Q: Detect if an iPhone app with given Apple ID and Bundle ID is already installed Is it possible to detect if an app with the given Bundle ID and Apple ID is already installed on the device? The app does not implement a custom URL Scheme. A: For the sake of completeness - the answer is no. // English (Ireland) [en-ie] import dayjs from 'dayjs' const locale = { name: 'en-ie', weekdays: 'Sunday_Monday_Tuesday_Wednesday_Thursday_Friday_Saturday'.split('_'), months: 'January_February_March_April_May_June_July_August_September_October_November_December'.split('_'), weekStart: 1, weekdaysShort: 'Sun_Mon_Tue_Wed_Thu_Fri_Sat'.split('_'), monthsShort: 'Jan_Feb_Mar_Apr_May_Jun_Jul_Aug_Sep_Oct_Nov_Dec'.split('_'), weekdaysMin: 'Su_Mo_Tu_We_Th_Fr_Sa'.split('_'), ordinal: n => n, formats: { LT: 'HH:mm', LTS: 'HH:mm:ss', L: 'DD/MM/YYYY', LL: 'D MMMM YYYY', LLL: 'D MMMM YYYY HH:mm', LLLL: 'dddd D MMMM YYYY HH:mm' }, relativeTime: { future: 'in %s', past: '%s ago', s: 'a few seconds', m: 'a minute', mm: '%d minutes', h: 'an hour', hh: '%d hours', d: 'a day', dd: '%d days', M: 'a month', MM: '%d months', y: 'a year', yy: '%d years' } } dayjs.locale(locale, null, true) export default locale Closer to God, closer to nature! Archive for 11:52 AM During the students´ holiday, a youth convention was organized at the Camp of our church, situated in Porumbacu. The number of participants was not very large, however those who attended enjoyed a time of beautiful fellowship, as well as the joy of winter time. The topics presented on this opportunity centered around „Friendship“, a relationship analyzed from the perspective of interpersonal interaction, the way in which we interact with the group of which we are a part, namely family and church; also, the friendship with Jesus, which will visibly bring about an improvement of the other social relationships.Q: ESR of Ceramic Capacitor I have been doing a bit research on ceramic capacitors, as I need one for the output of my synchronous buck converter. And as its very common that ESR is not straight forwardly given in the data sheets, we have to calculate it ourselves by Dissipation Factor value given at a certain frequency (normally 120 Hz) for a certain capacitance value. $$ESR = \dfrac{D \cdot F}{2 \pi f C}$$ For e.g if i have this ceramic capacitor I can calculate the ESR as $$ \dfrac{0.05}{2 \pi \cdot 120 \cdot 470 \mu F} = 141m\Omega$$ (page 1 of data sheet, calculating for 470uF cap). Now my question is, what if I am using this capacitor in my circuit at 100kHz? Its ESR should decrease right? As I think ESR should decrease with increasing the frequency. But the Dissipation factor increases with the increase in frequency as well. So how can one estimate the capacitor ESR at a high frequency? As there is no Frequency vs ESR OR Frequency vs D.F graphical relation given in the data sheets (I have gone through almost 100s of data sheets). So is there any way by which I can estimate the ESR of this capacitor at a higher frequency of 100kHz? Actually I will be charging my battery cell with the help of my buck converter and I need the capacitor ESR to be less than 10mOhms, because that is my Battery cell's ESR (mentioned in the data sheet), so I am trying to look for a ceramic capacitor with a lower ESR than this, for minimizing my voltage ripple at the output. Your helpful comments would be appreciated. Thankyou! A: While ESR is not always given it is often easy to find on a better manufacturers website. Many have online or downloadable tools that will show you all of the information you could ever want about a cap. With the rise of the need to simulate PDN for everyday boards, people have been demanding exactly this kind of information. For example take a look at Murata's simsurfing tool It's free of course and all you do is select a capacitor from the list and among other things you can see the graph of ESR and impedance vs frequency. If you're simulating it's easy to extract a simple RLC model from the data. A: If you are using that capacitor at 100kHz I might be interested in it's ESL - series inductance - it's a leaded part and quite large and this may swamp the resistance and give you horrible resonance problems: - I'd be looking for a capacitor that was specified more fully and it would more likely be a radial electrolytic. I would also consider the benefits of having it in parallel with a 1uF ceramic capacitor and maybe a 100nF - these sorts of devices are usually quite well specified by for high frequencies. My advice is find a more appropriate solution. Now my question is, what if I am using this capacitor in my circuit at 100kHz? Its ESR should decrease right? No, dissipation factor applies at a specific frequency - you can't just calculate ESR at F1 and expect it to become a different value at F2. Wiki tells us: - DF will vary depending on the dielectric material and the frequency of the electrical signals. A: The ESR equation works so long as you are below the resonant frequency of the cap. If you take a look at the impedance "notch" curve, the ESR should decrease up to the point where the cap is at its resonant point, after which you'll see the parasitic ESL begin to become more pronounced. This is where the equation above is incomplete (at the resonant frequency and above). Power Yoga Poses -The Cheapest Favour to your Body December 7, 2015 The approach of Power Yoga is the latest buzz that is bowling over the gaggles, but a ton of people are just muddled between the two terms i.e. ‘Yoga’ and ‘Power Yoga’ are they same? No, they are not alike; Yoga is the traditional system that is followed by the meditation process and steps to glom onto the crown of mind control and self recognition. While on the other hand the meditation steps followed in the Power Yoga aims at shaping the mind to be peaceful and calm. Its direction is towards the increased level of cholesterol in the body, Power Yoga targets to care about the cholesterol level. So this was all about ‘What is Power Yoga’. Power Yoga has grown throughout the world as this yoga does not involves just the strengthening of body and movements but it enmeshes the whole body and stepped out with flexibility and toning of body muscles not only this, a Power Yoga also educes the characteristics of what a good workouts can do. Power Yoga for weight Loss is one of the most crowd-pleasing forms of yoga that is considered to be most impressive and productive than other alternative forms. Power Yoga for weight Loss is well chosen as the simple yet natural way for losing weight. Practicing Power yoga on a regular basis has surely abetted countless people in paring down and gaining up weight. Weight Loss through Power Yoga is the best option that is now preferred by the herd as it does not have any adverse effect. Power Yoga Poses – The Postures for Mental Wellness Cobra Pose – How to do: The Cobra poses formants

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reeducation, cosmetic surgery if necessary, and they'll never have to work another day as long as they live—but they will want to work. Almost all of them do. I expect the navy will find places for them, paid consultants for their submarine warfare department, that sort of thing." "I want to meet them," the president said impulsively. "That can be arranged, sir, but it will have to be discreet," Moore cautioned. "Camp David, that ought to be secure enough. And Ryan, Judge, I want him taken care of." "Understood, sir. We're bringing him along rather quickly already. He has a big future with us." Tyuratam, USSR The reason Red October had been ordered to dive long before dawn was orbiting the earth at a height of eight hundred kilometers. The size of a Greyhound bus, Albatross 8 had been sent aloft eleven months earlier by a heavy-lift booster from the Cosmodrome at Tyuratam. The massive satellite, called a RORSAT, for radar ocean reconnaissance satellite, was specifically designed for maritime surveillance. Albatross 8 passed over Pamlico Sound at 1131 local time. Its on-board programming was designed to trace thermal receptors over the entire visible horizon, interrogating everything in sight and locking on any signature that fit its acquisition parameters. As it continued on its orbit and passed over elements of the U.S. fleet, the New Jersey's jammers were aimed upward to scramble its signal. The satellite's tape systems dutifully recorded this. The jamming would tell the operators something about American electronic warfare systems. As Albatross 8 crossed the pole, the parabolic dish on its front tracked in on the carrier signal of another bird, the Iskra communications satellite. When the reconnaissance satellite located its higher flying cousin, a laser side-link transmitted the contents of the Albatross' tape bank. The Iskra immediately relayed this to the ground station at Tyuratam. The signal was also received by a fifteen-meter dish located in western China which was operated by the U.S. National Security Agency in cooperation with the Chinese, who used the data received for their own purposes. The Americans transmitted it via their own communications satellite to NSA headquarters at Fort Meade, Maryland. At almost the same time the digital signal was examined by two teams of experts five thousand miles apart. "Clear weather," a technician moaned. "Now we get clear weather!" "Enjoy it while you can, Comrade." His neighbor at the next console was watching data from a geosynchronous weather satellite that monitored the Western Hemisphere. Knowing the weather over a hostile country can have great strategic value. "There's another cold front approaching their coast. Their winter has been like ours. I hope they are enjoying it." "Our men at sea will not." The technician mentally shuddered at the thought of being at sea in a major storm. He'd taken a Black Sea cruise the previous summer and become hopelessly seasick. "Aha! What is this? Colonel!" "Yes, Comrade?" The colonel supervising the watch came over quickly. "See here, Comrade Colonel." The technician traced a finger on the TV screen. "This is Pamlico Sound, on the central coast of the United States. Look here, Comrade." The thermal image of the water on the screen was black, but as the technician adjusted the display it changed to green with two white patches, one larger than the other. Twice the large one split into two segments. The image was of the surface of the water, and some of the water was half a degree warmer than it should have been. The differential was not constant, but it did return enough to prove that something was adding heat to the water. "Sunlight, perhaps?" the colonel asked. "No, Comrade, the clear sky gives even sunlight to the entire area," the technician said quietly. He was always quiet when he thought he was on to something. "Two submarines, perhaps three, thirty meters under the water." "You are certain?" The technician flipped on a switch to display the radar picture, which showed only the corduroy pattern of small waves. "There is nothing on the water to generate this heat, Comrade Colonel. Therefore it must be something under the water. The time of year is wrong for mating whales. It can only be nuclear submarines, probably two, perhaps three. I speculate, Colonel, that the Americans have been sufficiently frightened by the deployment of our fleet to seek shelter for their missile submarines. Their missile sub base is only a few hundred kilometers south. Perhaps one of their Ohio-class boats have taken shelter here and is being protected by a hunter sub, as ours are." "Then he will soon move out. Our fleet is being recalled." "Too bad, it would be good to track him. This is a rare opportunity, Comrade Colonel." "Indeed. Well done, Comrade Academician." Ten minutes later the data had been transmitted to Moscow. Soviet Naval High Command, Moscow "We will make use of this opportunity, Comrade," Gorshkov said. "We are now recalling our fleet, and we will allow several submarines to remain behind to gather electronic intelligence. The Americans will probably lose several in the shuffle." "Quite likely," the chief of fleet operations said. "The Ohio will go south, probably to their submarine base at Charleston or Kings Bay. Or north to Norfolk. We have Konovalov at Norfolk, and Shabilikov off Charleston. Both will stay in place for several days, I think. We must do something right to show the politicians that we have a real navy. Being able to track on an Ohio would be a beginning." "I'll have the orders out in fifteen minutes, Comrade." The chief of operations thought this was a good idea. He had not liked the report of the Politburo meeting that he'd gotten from Gorshkov—though if Sergey were on his way out, he would be in a good place to take over the job... The New Jersey The RED ROCKET message had arrived in Eaton's hand only moments before: Moscow had just transmitted a lengthy operational letter via satellite to the Soviet fleet. Now the Russians were in a real fix, the commodore thought. Around them were three carrier battle groups—the Kennedy, America, and Nimitz—all under Josh Painter's command. Eaton had them in sight, and had operational control of the Tarawa to augment his own surface action group. The commodore turned his binoculars on the Kirov. "Commander, bring the group to battle stations." "Aye." The group operations officer lifted the tactical radio mike. "Blue Boys, this is Blue King. Amber Light, Amber Light, execute. Out." Eaton waited four seconds for the New Jersey's general quarters alarm to sound. The crew raced to their guns. "Range to Kirov?" "Thirty-seven thousand six hundred yards, sir. We've been sneaking in a laser range every few minutes. We're dialed in, sir," the group operations officer reported. "Main battery turrets are still loaded with sabots, and gunnery's been updating the solution every thirty seconds." A phone buzzed next to Eaton's command chair on the flag bridge. "Eaton." "All stations manned and ready, Commodore," the battleship's captain reported. Eaton looked at his stopwatch. "Well done, Captain. We've got the men drilled very well indeed." In the New Jersey's combat information center the numerical displays showed the exact range to the Kirov's mainmast. The logical first target is always the enemy flagship. The only question was how much punishment the Kirov could absorb—and what would kill her first, the gun rounds or the Tomahawk missiles. The important part, the gunnery officer had been saying for days, was to kill the Kirov before any aircraft could interfere. The New Jersey had never sunk a ship all on her own. Forty years was a long time to wait. "They're turning," the group operations officer said. "Yep, let's see how far." The Kirov's formation had been on a westerly course when the signal arrived. Every ship in the circular array turned to starboard, all together. Their turns stopped when they reached a heading of zero-four-zero. Eaton set his glasses down in the holder. "They're going home. Let's inform Washington and keep the men at stations for a while." Dulles International Airport The Soviets outdid themselves getting their men away from the United States. An Aeroflot Illyushin IL-62 was taken out of regular international service and sent directly from Moscow to Dulles. It landed at sunset. A near copy of the British VC-10, the four-engine aircraft taxied to the remotest service area for refueling. Along with some other passengers who did not deplane to stretch their legs, a spare flight crew was brought along so that the plane could immediately return home. A pair of mobile lounges drove from the terminal building two miles to the waiting aircraft. Inside them the crewmen of the Red October looked out at the snow-dusted countryside, knowing this was their final look at America. They were quiet, having been roused from bed in Bethes

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Wymagane', type: 'Typ', typeText: 'Tekst', typePass: 'Hasło', typeEmail: 'Email', typeSearch: 'Szukaj', typeTel: 'Numer telefonu', typeUrl: 'Adres URL' } } ); WE are familiar with the parable of the lost sheep that holds so many precious lessons for us. (cfr Lk 15,1-7) We should try to be that shepherd who was willing to leave behind 99 faithful sheep to look after the one who went astray and got lost. We can imagine what that shepherd went through to look for that sheep. For a sheep to get lost can mean that it went to another area where it and the other sheep should not go. And so the shepherd must have explored some unfamiliar places to find it. It’s not...If a design is taking too long then it’s the wrong design Elon Musk Everyday Astronaut Interview This is by far the topic I get the most push back from engineers about. Even more than Software Engineering is Writing. They always want to go slower, more carefully. The idea of doing what they’re doing now but faster seems crazy. It is crazy. You can’t go faster doing what you’re doing now. Instead I want us to change what we’re doing to go faster. Why should we be trying to go faster? In short, because we’re professionals. Professionals vs Hobbyist Activity Professional Hobbyist Driving 200 MPH 65 MPH Football QB decision to pass or run 3 sec 10 sec Cleaning a 1br Apartment 4 hr 1 day Baseball fastball 90 MPH 50 MPH Programming – implementing a single screen of a prototype UI 1 month 2-3 days An almost universal difference between a professional and a hobbyist in every job is speed. Professionals are faster than amateurs. Most of the above data comes from the book “Wait: The Art and Science of Delay” by Frank Partnoy. The title is an interesting choice as the main argument I get out of the book is: Focus on speed. Speed allows you to wait longer to take action. Waiting longer allows you to gather more information, which increases the likelihood of a better outcome. It reminds me of the Special Forces phrase: “Slow is smooth and smooth is fast”. The last line in the table comes from a friend at Google. They told me this is how long it takes them to make a single prototype screen for a UI. I nearly spit out my coffee. I chose this because the majority of programmers I talk with are Googlepheliacs who think everything they do is “the way” and should be emulated always, everywhere. Speed of what? If you want a metric, the one I’m currently using is: Working software, in the hands of customers, as quickly as possible with as low a defect rate as possible. Another valid approach might be something like: minimizing median time to feedback. But won’t quality suffer? No, I don’t believe so. It might at first, as people who are used to driving their car straight until they hit a guard rail realize they might actually have to learn how to drive. But on the whole I believe the quality of your programming skills increase faster with the quantity of finished products more than slow reasoned debate. If that’s true then the faster you build products, the faster your skills develop. The following story illustrates the impact of speed on quality: The ceramics teacher announced on opening day that he was dividing the class into two groups. All those on the left side of the studio, he said, would be graded solely on the quantity of work they produced, all those on the right solely on its quality. His procedure was simple: on the final day of class he would bring in his bathroom scales and weigh the work of the “quantity” group: fifty pounds of pots rated an “A”, forty pounds a “B”, and so on. Those being graded on “quality”, however, needed to produce only one pot – albeit a perfect one – to get an “A”. Well, came grading time and a curious fact emerged: the works of highest quality were all produced by the group being graded for quantity. It seems that while the “quantity” group was busily churning out piles of work – and learning from their mistakes – the “quality” group had sat theorizing about perfection, and in the end had little more to show for their efforts than grandiose theories and a pile of dead clay. “Art & Fear” by David Bayles & Ted Orland John Carmack approves in principle: Similar to above but more science: “Ok, I’m not gonna click on any of that, but how would you propose we accomplish this?” I hear you say. Well, I have some thoughts… Work on the problem in front of you Stop trying to predict the future (“future proofing systems”) and just solve the problem you’re trying to solve with the minimal amount of code necessary. The current approach is hurting in the following ways: We’re all bad at predicting the future, so what you write may never be necessary. It takes more time to write the future proof version of the code. Creating flexibility requires abstraction. This abstraction is implemented through indirection. Every layer of indirection adds cognitive load that is unnecessary and unrelated to the task (sometimes called incidental complexity). Good abstractions are difficult to make correctly and require lots of examples to do well. Repeat Yourself A little bit of code duplication is better than maintaining 20+ abstract types. — Jaana B. Dogan ? (@rakyll) February 12, 2020 *gasp* I use the Rule of 3: I will copy and paste the same code twice. Once there is a third concrete need for that same code, I then feel like I have enough information that the likelihood of creating the appropriate abstraction is high. Don’t Break Tools! Two years ago I quit my job and decided to strike out on my own. Since I was programming for myself, I thought there’s no harm in using a programming language I love and had used to great success in production elsewhere, and so I wrote everything in F#. I truly believe that F# is the best language on the .NET platform and has the superior programming model for eliminating entire categories of bugs (no null, for example). I believed the strong type checker would help me move more quickly than in C#. I was wrong, but not for the reason I originally thought. For the last 6 months I’ve moved back to C# for only one reason. Tooling. All of the tooling around C# really increases your productivity with the language despite some of the issues around null, verbosity around types, etc. in F# I had to write the simple database migrations myself or otherwise jump through hoops to have a single C# project linked to my F# project so that EF Core would do the magic. The same thing is true for writing mobile apps with Xamarin. The tooling for C# ‘just works’, while for F# there’s a lot of gotchas and edge cases that you need to figure out. The time to go from idea to working code either in the browser or on my mobile device is shorter with C# because of the tooling aiding me in writing correct robust code. So this has changed my language stack-rank. I’ve found it’s preferable to use the ones with the best tools. Modern IDEs, debuggers, profilers, static analysis tools all help you immensely to speed up the time it takes to write correct, robust code. If you’re not using them, then you don’t even know what you’re missing. I like VIM as much as the next person, but it doesn’t hold a candle to Visual Studio or IntelliJ in terms of productivity. Yet in almost every large project I’ve worked on, no matter the language, someone has broken the tooling. Usually the culprit is the build. They’ve put things in non-standard directories and then write their own build script to re-assemble everything in the correct place for CI… but I wish they had just taken the time to get it working for everyday developers in the standard tool. Testing and Other Quality Control I’ve heard arguments from the TDD crowd that although testing requires more upfront work it actually makes you go faster. This is not born out by the evidence in the book “Making Software: What Really Works, and Why We Believe It” by Andy Oram, Greg Wilson which is as close as I’ve been able to find to someone using the scientific method to measure things about software engineering processes. You can quibble about the testing methodologies of the underlying papers, but it’s still peer reviewed and published data, which is better than any blog post, including this one. Testing absolutely helps when a project is so large you can’t keep it all in your head, but it’s not an unalloyed good. Testing makes permanent. Maybe that’s what you want, but maybe it’s not. How can we tell the difference? A maturity model of software is useful here. A Maturity Model of Software I think it’s obvious on its face that not all software is created equal. Software that crashes is probably fine for a prototype of an Instagram clone – but not so much for avionics or automobiles

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boost sessions are typically delivered with an electron beam, which is designed to treat the primary lumpectomy site only. Unlike photons, whose intensity decreases in an approximately exponential fashion within the patient, electrons deposit most of their dose within a fixed, finite range which depends on the energy of the beam. Thus, a single electron beam can be used to treat superficial lesions while sparing underlying healthy tissues. Electron treatments are delivered with electron cones of various sizes and shapes that are typically attached to the collimator of a linear accelerator, and which shape the electron beam very close to the patient surface. The shapes can be standard geometric shapes, such as circles or squares of various sizes, or an arbitrary shape can be custom-made for a given patient. In some instances, a lead sheet having an opening that defines the aperture of the beam is placed directly on the patient's skin. Electron treatments are usually planned with a fixed source-to-skin distance (SSD). Breast boosts (a radiotherapy treatment in which a “boost” of 10-16 Gy of radiotherapy is given in addition to the normal radiotherapy treatment after surgery) typically use an SSD of 100 cm, as this is the same distance from the beam source to the isocenter of most linear accelerators (“linacs”). As a result, the linac isocenter, and hence the intersection of any wall lasers being used to align the patient with the linac, lies on the patient skin surface. This is in contrast to many photon treatments, which are planned such that the isocenter is near the center of the treatment volume. For a breast boost, the electron field ideally should cover the tumor bed and the surgical path leading from the tumor bed to the surgical scar, plus a 1-2 cm margin. In addition, it is preferable to avoid the areola. Unfortunately, the location of the scar, which is used often as a proxy for the lumpectomy site to aim the electron beam, is often a poor indicator of the actual location of the underlying tumor bed. Ultrasound has been used for planning purposes to obtain the size and shape of the tumor bed, or seroma, which is the fluid-filled region of the lumpectomy site. Surgical clips, placed during surgery around the lumpectomy site, are radio-opaque and have also been used as a proxy for the lumpectomy site for planning purposes. What is needed, however, is a methodology to incorporate internal information, e.g., the position and extent of seroma as observed in ultrasound images, into the conventional clinical setups (simulation and/or treatment) for electron breast boost treatments.This invention relates to metal complexes and to addition polymerization catalysts formed therefrom that have improved catalytic performance. More particularly the present invention relates to an addition polymerization catalyst composition comprising a Group 3, 4, or Lanthanide metal complex containing a boratabenzene group or divalent derivative thereof bonded via its delocalized xcfx80 electrons to the metal (also referred to as a boracyclohexadienyl group). In addition, the present invention relates to certain of the foregoing complexes possessing a novel bridged structure. Finally, the invention relates to a method of using the foregoing catalyst compositions in an addition polymerization process for polymerizing addition polymerizable monomers. In EP-A-416,815 there are disclosed certain constrained geometry metal complexes and catalysts derived by reacting the metal complex with activating cocatalysts. Supported derivatives of such catalysts were prepared by contacting them with a support such as alumina, silica or MgCl2. In U.S. Pat. No. 5,064,802 (EP-A-418,044) there are disclosed certain further catalysts formed by reacting metal complexes with ion forming activating cocatalysts that are salts of Bronsted acids containing a non-coordinating compatible anion. The reference discloses the fact that such complexes are usefully employed as catalysts in addition polymerizations. In EP-A-520,732 an alternative technique for preparing cationic constrained geometry catalysts using borane activators is disclosed. In U.S. Pat. No. 4,892,851 there are disclosed biscyclopentadienyl Group 4 metal complexes, especially complexes of zirconium or hafnium that are usefully employed with alumoxane activating cocatalysts for use in addition polymerizations, especially the polymerization of aliphatic xcex1-olefins. In a series of patents, W. Spaelick has disclosed certain ring substituted stereorigid bisindenyl complexes and their use as olefin polymerization catalysts. The bridging group of such complexes generically includes silicon, germanium or tin containing divalent groups containing hydride, halogen, C1-10 alkyl, C6-10 fluoroalkyl, C6-10 aryl, C6-10 fluoroaryl, C1-10 alkoxy, C2-10 alkenyl, C7-40 aralkyl, C8-40 aralkenyl or C7-40 alkylaryl groups or ring forming combinations thereof. Such disclosure may be found in U.S. Pat. No. 5,243,001, U.S. Pat. No. 5,145,819, U.S. Pat. No. 5,304,614, U.S. Pat. No. 5,350,817, among others. Boratabenzenes are anionic ligands which are boron containing six membered ring systems. They are previously known in the art having been described by A. Ashe, et al., J. Am. Chem. Soc., 93, 1804-1805 (1971). They may be prepared by reaction of 1,1-diorgano-1-stannacyclohexa-2,5-diene and a borontrihalide followed by substitution with a hydrocarbyl, amino, silyl or germyl group. Such ligand groups correspond to the formula: wherein J is selected from the group consisting of hydrogen, hydrocarbyl, dihydrocarbylamino, silyl, germyl, halohydrocarbyl, or halocarbyl, said J having up to 20 non-hydrogen atoms. It would be desirable if there were provided an improved catalyst system based on the foregoing boratabenzene groups as well as an improved addition polymerization process utilizing such catalyst systems. As a result of investigations carried out by the present inventors there have now been discovered new and improved Group 3, 4, or Lanthanide metal complexes corresponding to the formula: or a dimer, solvated adduct, chelated derivative or mixture thereof, wherein: Y is a divalent derivative of a boratabenzene group or a hydrocarbyl-, dihydrocarbylamino-, silyl- or germyl-substituted boratabenzene group containing up to 50 nonhydrogen atoms that is bonded via its delocalized xcfx80-electrons to M; L is Y or a hydrocarbadiyl group that is bound to M by means of its delocalized xcfx80-electrons, or L is a monovalent or divalent amido group, said L group containing up to 50 nonhydrogen atoms; M is a metal of Group 3, 4 or the Lanthanide series of the Periodic Table of the Elements; Z is a covalently bound, divalent substituent of up to 50 non-hydrogen atoms having the formula, xe2x80x94(ER22)mxe2x80x94, wherein E independently each occurrence is carbon, silicon or germanium, R2 independently each occurrence is selected from the group consisting of hydrocarbyl, hydrocarbyloxy, silyl, and germyl of up to 20 atoms other than hydrogen, and m is an integer from 1 to 3; Xxe2x80x2 is a neutral ligand having up to 20 non-hydrogen atoms; Xxe2x80x3 independently each occurrence is a monovalent, anionic moiety selected from hydride, halo, hydrocarbyl, silyl, germyl, hydrocarbyloxy, dihydrocarbylamide, siloxy, halohydrocarbyl, halosilyl, silylhydrocarbyl, and dihydrocarbylaminohydrocarbyl having up to 20 non-hydrogen atoms, or two Xxe2x80x3 groups together form a divalent hydrocarbadiyl group; n is a number from 0 to 3; and p is an integer from 0 to 2. According to the present invention there are further provided improved addition polymerization catalyst compositions comprising an activating cocatalyst and one or more Group 3, 4 or Lanthanide metal complexes corresponding to the formula: or a dimer, solvated adduct, chelated derivative or mixture thereof, wherein: Yxe2x80x2 is a boratabenzene group or a hydrocarbyl-, dihydrocarbylamino-, silyl- or germyl-substituted boratabenzene group containing up to 50 nonhydrogen atoms that is bonded via its delocalized xcfx80-electrons to M; Lxe2x80x2 is Yxe2x80x2 or a hydrocarbyl group that is bound to M by means of its delocalized xcfx80-electrons, or Lxe2x80x2 is an amido group, said Lxe2x80x2 group containing up to 50 nonhydrogen atoms; L and Y are as previously defined; M is a metal of Group 3, 4 or the Lanthanide series of the Periodic Table of the Elements; Z is a covalently bound, divalent substituent of up to 50 non-hydrogen atoms having the formula,

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Poniatowski, king of Poland 202, 203 Stanley, H. M. 254 Starya Ladoga, Russia 113 Staufen emperors 109 steam power 206 steamships, development of 229, 263–264 steel output 220 Stephen, king of Hungary (997–1038) 98, 101 Strategic Arms Limitation Treaty (SALT) (1972) 293, 325 Stuttgart, Germany 196 Su-chou, China 166 Sudan 135; British conquest of 258; British reconquest of 255; civil war in 316; Nile valley 15; war in 309, 311, 312 Sudan, Nilotic 252 "Sudanic belt" 134, 135 Sudetenland 282 Sueves 85 Suez, Egypt 167; canal 152, 246; invasion (1956) 295 Su. saints 128 sugar, cane 152, 181 sugar trade 203, 204 Suhar, Yemen 87 Suharto, President 301, 304 Sui dynasty (581–618) 65, 67, 117 suicide bombers, Muslim xxviii–xxix, 340 suicide ( _kamikaze_ ) pilots 285 Sukarno, Achmed 274, 300–301 Sukarnoputri, Megawati 304 Sukhothai, kingdom 130 Suleiman the Magnificent (1520–66) 138, 167, 168 Sultaniya, Azerbaijan 120 Sumatra 5, 180 Sumerian civilization xxxi Sumerian language 31 Sumitomo family 177 Sun Yat-sen 245, 274, 275 Sunda shelf 23 Sung dynasty 66, 117, 118–119 Sung-chiang, China 166 Sunni Ali, king of Songhay 135, 163 Sunni Muslims xxx, 169, 316, 339 Sunni Seljuk Turks 131, 132, 133 Superior, Lake 229 Suppiluliuma (1344–1322 BC) 34 Surat, India 157 Susa, Mesopotamia 30, 31 Susilo Bambang Yudhoyono 304 Sven, king of Denmark 100 Svyatoslav, Grand Prince ( _c_. 962–72) 107 Svyatoslavich, Vladimir (980–1015) 107 Swahili-Arabs 252 Sweden: 900 to 1050 100; Baltic empire 192–193; breaks away from Scandinavian Union 192; power, decline of 194; wars with Denmark (1643–5, 1657, 1658, 1676–9) 193, 194 Swedes 99, 108 Swedish migrants 233 Swiss Confederation 141 Swiss migrants 233 Syria 33, 55, 87–88, 132, 272 "Syrian jugglers" 53 Szechwan, tribal risings in (1746–9, 1771–6) 172 Tabon Cave, Palawan 20 Tabriz, Iran 120, 122 Tahiti 258 T'ai-p'ing rebellion 244 Taika revolution (645) 115 Taino people 37, 145, 146 Taira clan 116 Taiwan (Formosa) 256, 259, 277; early cultures in 41; since 1945 296, 297 Taj Mahal, India 171 Tajikistan 120 Takauji, Ashikaga 116, 117 Taliban 308, 338 _Talmud_ (ad 500) 93 Tamerlane (Timur) 120–121, 124, 128, 137, 170; followers of 119 Tamil Tigers (LTTE) 307 Tamils 307 T'ang Chinese armies 115 T'ang dynasty 43, 117–118 Tanganyika 254, 260, 272 Tanganyika, Lake 252 Tangier 191 Tanguts 118 Tannenberg, B. of (1914) 266 Tanzania, "Ujamaa" policies 310 Tanzimat reforms 240–241 Taoism xxii Tapajós chiefdom 144 Taranaki, New Zealand 250 Taranto, Italy 97 Tarim Basin 118 Tariq ibn Ziyad 89 Tashkent 170 Tasmania (Van Diemen's Land) 248 Tatar Chin 119 Tatar invasions xxxiv Taxila 69 tea trade 205 technologies: development of xxxi–xxxii, xxxv–xxxvi; early 3; Western, export of xxxviii Teheran conference (1943) 287 Tehran, Iran 169 telecommunications 344–345 telegraph service, US 227–228 telephone, invention of 343 Tell 'Uqair, Mesopotamia 30 Templars 103 temples: Central Andes 19; early 13 Tenasserim 180 Tenedos 201 Tennessee River 232 Tenochtitlán xxxv, 145, 146 Teotihuacán, Mesoamerica 38 Ternate 131, 156 terror, rise of, and religion 340 "terror, war on" 326, 335 terrorism, world, since 1945 335–337; and nation-building 336; and social revolution 336–337 Tertry, B. of (687) 95 Teutonic Knights 104, 108, 140 Teutonic Order 192 Texas 160 Texcoco, Lake 145 textile industry 206, 219, 229 Thailand: 1954 to 1975 301; since 1975; Buddhist shrines in 129; early man in 20, 21; French in 179; military coup (2006) 305 Tham Khuong, Vietnam 20 Thebes, Egypt 33, 55, 60 Theodoric 86 Theodosius 81 Thera, volcano 48 Theravada Buddhism 131; teachings 68–69 Thessaly 61, 106 Third Department 242 Thirteen Years' War (1654–67) 158 Thirty Years' War (1618–48) 93, 191, 193, 194, 195 Thomson, Joseph 343 Thorn, burghers rebellion 192 Thorn, Peace of (1466) 192 Thrace 61, 85, 106 Three Feudatories, rebellion of (1674–81) 172 Thucydides 60 Ti people 66 Tiahuanaco, Bolivia 36 Tiber, River 73 Tiberius (14–37) 76 Tibet 275 Tidore 131 Tiglath-pileser III (744–727 BC) 55 Tigris valley, lower 27, 28, 30 Tikulti-ninurta I (1233–1197 BC) 35 Tilsit, Treaty of (1807) 213 Timbuktu, Niger 135, 163 "Time of Troubles" (1605–13) 158 Timur _see_ Tamerlane Tipu Sultan 171, 209 Titicaca Basin, Bolivia 36 Tito, Marshal 290 Titus (79–81) 76 Tlatelolco 145 Toba volcano, Sumatra 5 tobacco 152; trade 203, 204 Tocharians 57 Togoland 254, 272 Tokugawa Ieyasu 176 Tokugawa Shogunate xxxvii, 176–178 Toltecs, rise of the 38–39 Tongan region 24 tools, early xxxi, 3, 22, 15; Asian 20 Tordesillas, Treaty of (1494) 154, 162 Toronto, Canada 236 Toul 197 Toulouse, France 85 Toungoo, Myanmar 130 Touraine 111 Tournai, France 95 Toxandria 85 Toynbee, Arnold: _A Study of History_ xviii Toyotomi Hideyoshi (1536–98) 176 trade, Baltic 192 trade, global ( _c_. 1775) 203–205; Asia, trade with 205; mercantilism 203–204; slave economy 204–205; and "triangular" 152, 203, 204 trade, Neolithic 12–13 "trade diasporas" 53 trading, early, in Eurasia 29, 30–31 trading empires, expansion of (1500 to 1700) 155–157; Dutch expansion 156–157; European rivalries 157; Portugal's trading empire 156; trading routes, Eurasian 52–54, 64 Trafalgar, B. of (1805) 213 Trajan (98–117) 76

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ed of just a window? :-) <louise> how do I install the driver for a 802.11b/g wireless network card, in ubuntu ? <werdnum> Hi! When I resume from suspend, my screen goes bananas and I have to alt-sysrq-K to get back to a sensible X terminal <werdnum> s/terminal/session/ <ardchoille> stian: right click the workspace switcher and choose Preferences <stian> Yes but preferences isent there (?) <DawnLight> quanta+ is not develoed anymore, is it? <stian> Can adjust how many workspaces i want, thats it. <Rec0> ehm could someone help me i've got a fresh ubuntu installed but it doesn't load it says grub error 2 <Rec0> i've got multiple hdd's in my pc (3 and a dvd-burner) <Slart> stian: it seems there used to be a checkbox for this.. there is still a variable in gconf-editor for it <richard> greetings, and merry christmas <Guest29648> i have a problem with the amsn audio and video <Guest29648> can someone help, i am using intrepid <stian> Slart: Will take a look :-) Thanx <shoeunited> I've found a solution to a "screenshot gallery of a movie" that has been plauging some users for a long time. Where should I make a topic for it? <crow> is there already .dev package for mplayer_vdpau to test? <shoeunited> In the forums, I mean. <Slart> stian: seems it only works if you're running metacity though =/ <Guest29648> i have a problem with the amsn audio and video <Guest29648> no audio and video <stian> Running the same ubuntu on the laptop and there i have given them names.... but here i just cant find it.. <richard> i have a problem with the amsn audio and video <richard> no audio and video <Guest11676> help please <FiremanEd> !ask | Guest11676 <ubottu> Guest11676: Please don't ask to ask a question, simply ask the question (all on ONE line, so others can read and follow it easily). If anyone knows the answer they will most likely reply. :-) <Guest11676> well i try to call someone with amsn but it say something about /dev/dsp <man> hello <man> can you help me? <FiremanEd> !ask | man <ubottu> man: Please don't ask to ask a question, simply ask the question (all on ONE line, so others can read and follow it easily). If anyone knows the answer they will most likely reply. :-) <Guest11676> ok <eleos2> what is the shortcut of changing the language <eleos2> ? <PurplePlus> eleos2 alt+shift doesn't work? <eleos2> purpleplus no <man> allo <ardchoille> PurplePlus: alt+shift brings up the window menu bydefault <bitsbam> hey all, is there a way when i share a drive ( either with samba or nfs, don't care which ) that i can make 2 drives appear as one to the client computer? I guess i am looking for a program that will do this. <bartek> hi, I keep getting Could not get lock /var/lib/dpkg/lock - open (11 Resource temporarily unavailable) .. It's because I have a "aptitude search w" running in my ps but how can I kill it? I've tried sudo kill <pid> and kilall aptitude but no luck it just sits there. Any tips? <melch> Hey can someone help me install adobe air on a 64 bit install? <joaopinto> bitsbam, sure, just make sure those drives are mounted inside your share path <joaopinto> !aptlock | bartek <ubottu> bartek: If an APT front-end crashed and your database is locked, try this in a !terminal: Â« sudo fuser -vki /var/lib/dpkg/lock;sudo dpkg --configure -a Â» <bartek> What does that do before I run it? <bartek> brief summary :-) <gauravkumar> tryin to install warcraft III on hardy.. i have a dell inspiron 1525 .. intel 965 video .. i get a black screen when i run with wine and nothin else... any help? <joaopinto> bartek, it kills the process locking that file <mint_> hi guys, i have a problem with java, everytime i try to use a digital certificate with java, it show me a pop up to select it, but there's no certificate (and i've already imported it), any suggestion? <error404notfound> I am in single user mode, I have /,/var,/boot,/var/www and I want to run fsck on them but it says that they are mounted, when I try to unmount them ubuntu cries about them being busy <bartek> ok <bartek> thanks <eleos2> what is the keyboard shortcut of changing the default language <eleos2> ? <joaopinto> !wine | gauravkumar <ubottu> gauravkumar: WINE is a compatibility layer for running Windows programs on GNU/Linux - More information: https://help.ubuntu.com/community/Wine - Search the !AppDB for application compatibility ratings - Join #winehq for application help <bartek> awesome .. thanks joaopinto ! <melch> !adobe air <ubottu> Sorry, I don't know anything about adobe air <joaopinto> eleos2, I am not aware of a shortcut for that, it's available from System -> Admin -> Lang Support <kanibalizm> gosh <kanibalizm> so many ppl <joaopinto> error404notfound, are you sure you booted in recovery mode ? Have you untried to unmount them ? <kanibalizm> who can help about UBUNTU :) <joaopinto> !anyone | kanibalizm <ubottu> kanibalizm: A large amount of the first questions asked in this channel start with "Does anyone/anybody..." Why not ask your next question (the real one) and find out? <em123> hi, please tell me one livecd that have these 3 feature, 1, minimal, 2, make, gcc, 3, after startup, the livecd can been pull out and put another cd into cdrom drive <error404notfound> joaopinto: I am in recovery mood, from there I select root shell option, I have also tried to unmount them... <kanibalizm> shoul id ask in channel :) <joaopinto> em123, the ubuntu live cd does not allow that <joaopinto> !ot | em123 <ubottu> em123: #ubuntu is the Ubuntu support channel, for all Ubuntu-related support questions. Please use #ubuntu-offtopic for other topics. Thanks! <gauravkumar> joaopinto: i did install through wine and finally when i try to run the exe i get a black blank screen.. also noteworthy.. i get direct rendering: No (LIBGL_ALWAYS_INDIRECT set) from glxinfo <melch> Anyone have any info on adobe air and ubuntu <em123> ok <joaopinto> gauravkumar, "direct rendering: No" means you are not using the 3d capable drivers <joaopinto> gauravkumar, System -> Admin -> Hardware drivers <simon_> hi. since upgrade/update I get I/O errors with my cdrom drive (only with audio disc, not with data cds) <joaopinto> check if there is a recognized proprietary drivers for your card <kanibalizm> This is a major failure of your software management system. Please check for broken packages with synaptic, check the file permissions and correctness of the file '/etc/apt/sources.list' and reload the software information with: 'sudo apt-get update' and 'sudo apt-get install -f'. <kanibalizm> this i what i have :) <joaopinto> kanibalizm, on the terimnal run: sudo apt-get install -f <kanibalizm> jabagawee you can help ? <joaopinto> as suggested by the message <gauravkumar> joaopinto: Hardware drivers doesnt list anything.. tried to get something relevant by using envy but this is an intel chipset and envy is for nvidia and ati <ardchoille> joaopinto: I have a vid card and after installing ubuntu direct rendering says yes, but the 3d drivers are not installed. I don't think direct rendering means 3d capable <joa

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Tattletale. Snitch. Rat. Job loss and ruptured relationships are common consequences; so is grief over the loss of a once-shared identity. Whistleblowing can end with ignominy, imprisonment or exile. Sometimes it is a secret carried to the grave, or nearly so. “I didn’t, I couldn’t, even use that word about myself — whistleblower,” said Jacqueline Garrick, 56, the founding director of a Department of Defense suicide prevention program who said she ran afoul of Pentagon officials when she raised still-contested allegations, first internally and then publicly, of fraud and abuse. A former Army officer, Garrick likened her experience in the three years since she came forward to the post-traumatic stress sometimes suffered by combat veterans — sleeplessness and anxiety, isolation and despair. She went on to found a peer-support group, Whistleblowers of America, to help others deal with the psychological and practical consequences of making accusations of workplace wrongdoing. “You just don’t realize at first,” she said, “that your life is never going to be the same.” :: The whistleblower at the center of the Trump impeachment inquiry, reportedly a CIA analyst temporarily assigned to the White House, probably had a better sense than most of what might lie ahead. The individual’s complaint, filed Aug. 12, landed like a bombshell in official Washington when the House Intelligence Committee made it public on Sept. 26. Except for two blacked-out paragraphs in a classified appendix, the nine-page document spelled out in crisp, measured prose the writer’s belief that Trump was “using the power of his office to solicit interference from a foreign country in the 2020 U.S. election.” Acting Director of National Intelligence Joseph Maguire said the whistleblower who came forward in August with a complaint about President Trump’s dealings with Ukraine followed the required steps in reporting such concerns. (Kirk McKoy / Los Angeles Times) The acting director of national intelligence, Joseph Maguire, told lawmakers that the whistleblower had followed the law “every step of the way” in submitting it to the intelligence community’s inspector general. Disclosure of the complaint prompted a response familiar in the annals of whistleblowing: attack the messenger. The president denounced the whistleblower as a “partisan hack,” a “Deep State” operative, “close to a spy,” a betrayer of trust. Trump said the whistleblower should be unmasked — contrary to legal guarantees of anonymity — and demanded to personally confront his accuser. Although federal rules do not require a whistleblower’s information be firsthand, the president seized on the fact that the complainant acknowledged not having heard Trump’s crucial July 25 telephone call with Ukrainian President Volodymyr Zelensky, when Trump pressured the new leader to investigate his political rival, Joe Biden. But the declassified White House memorandum of the call, essentially a rough transcript, appeared to confirm large parts of the whistleblower’s complaint. President Trump has attacked the Ukraine whistleblower allegations. (Win McNamee / Getty Images) Lawyers representing the whistleblower said over the weekend that a second individual had come forward, also from the intelligence community. That is also a well-worn whistleblower scenario — especially if the second individual brings firsthand knowledge that could bolster the original complaint. On Sunday, 90 former national security officials — with service under both Republican and Democratic presidents — released an open letter calling for privacy and protection from retaliation for the person whose complaint set the impeachment inquiry in motion. “A responsible whistleblower makes all Americans safer,” they wrote. :: The term “whistleblower” is of uncertain origin, thought to refer to a police officer’s response when spotting a criminal, or to a sports referee calling out a foul. But most researchers say its animating principle dates to medieval times, with recognition of the right of individuals, not only officialdom, to sound the alarm about wrongdoing. In English common law, the writ of qui tam meant a private individual who assisted in an official prosecution was entitled to a share of the penalty paid. So it carried a connotation of bounty hunting, when a person was acting “for the king as well as for self.” Richard Nixon resigned as president in 1974 amid the Watergate investigation, which was fed in part by a whistleblower then known as “Deep Throat.” (Associated Press) In the United States, the term “whistleblower” only came into wide use around 1975, with headline-grabbing cases such as the Pentagon Papers, which exposed White House deceit in the Vietnam War, the Watergate scandal that brought down President Nixon, and the work of crusading of consumer advocate Ralph Nader. Stanger’s book, “Whistleblowers: Honesty in America From Washington to Trump,” details the case of the Revolutionary War seamen who won the legal protection of the Continental Congress when their wealthy and well-connected commodore, Esek Hopkins, sought to retaliate against them for reporting him. The Civil War ushered in incentives for exposing graft associated with the procurement of military supplies. In modern times, landmark legislation included the Whistleblower Protection Act of 1989 and several major updates in the following three decades. But advocates say federal workers, and especially members of the intelligence community, still lack sufficient protections if they expose wrongdoing. “To truly protect whistleblowers, there’s a lot of unfinished business,” said David Colapinto, general counsel for the National Whistleblower Center. :: Al Pacino portrays Frank Serpico in the 1973 movie “Serpico.” The New York police officer exposed corruption in the NYPD. The real Frank Serpico, right, with his attorney, Ramsey Clark, testifies before the Knapp Commission investigating police corruption in 1971. Serpico, who helped clean up the NYPD, became a pariah among his former co-workers. (Associated Press) The Hollywood image of a feisty firebrand spoiling for a fight is rarely reflected in reality, according to Tom Mueller, who said he interviewed 200 whistleblowers for his book on the subject. Many whistleblowers believe their own organization will fix whatever wrong they brought to light, and are shocked and disillusioned when that doesn’t happen. And although a few may be disgruntled employees — another popular assumption that clings to whistleblowers — many more are motivated by personal values, Mueller said. Elin Baklid-Kunz said her upbringing in Norway, with its societal emphasis on equality and the common interest, led her to complain of serious financial misconduct at the Florida hospital where she worked, including overbilling Medicare and paying kickbacks. “I just wasn’t raised to think I was better than anyone else, or to think it was all right to take advantage of others,” said Baklid-Kunz, who appeared with Mueller at a recent panel on whistleblowing at a Washington bookstore. The crowd groaned at the description of hospital officials performing a bizarre “money dance,” with rap lyrics and costumes festooned with dollar signs, to convey the message that extracting cash, not patient care, was the top priority. Mueller’s book, “Crisis of Conscience: Whistleblowing in an Age of Fraud,” takes a Martin Luther King Jr. quotation as its epigraph — reflecting, he said, a worldview that many who blow the whistle finally, reluctantly, take to heart. “A time comes,” the civil rights icon told a New York City congregation in 1967, the year before his assassination in Memphis, “when silence is betrayal.”Alan Park survived cancer by using cannabis oil. He talks to us about it, his journey and his new podcast “Green Crush”. Why is Cannabis illegal? All questions answered on the Fringe. BRV, Bin Hamin, Josh Cory Host. ... William Ramsy joins us to discuss the prophet of Evil Aleister Crowley and how he has influenced pop culture. Crowley is the prophet of the Elite Religion. What are the Crowlian connections to Pizza gate? Was 911 a magic ritual sacrifice? Is Jay – Z a follower of the Crowley doctrine? BRV, Bin Hamin and... Richard Gage of Architects and Engineers for 911 Truth joins the fringe to discuss his activities on Seot 11th 2017 and review the evidence for the Implosion of the Twin Towers and Building 7 on September 11th 2001.Jimmy Gene of Enter the Microcosm joins us at the beginning of the hour to discuss our 911... PLANET X ARRIVES OCTOBER 2017? With David Meade aka The Profit of DOOM!! It’s supposed to happen according to him! Lets hope not. Do your own research!! We get into Biblical Prophecy and the signs in the skies that indicate planet X is on the way.. David Meade joins us to discuss. Josh Cory, Bin... THE VIEWS AND OPINIONS EXPRESSED ON THIS STATION BELONG SOLELY TO THOSE WHO MAKE THEM AND DO NOT NECESSARILY REFLECT THE VIEWS AND OPINIONS OF TRUTH FREQUENCY RADIO, iHeartRadio, OR OUR AFFILIATES / ADVERTISERS.Can Aging Develop as an Adaptation to Optimize Natural Selection? (Application of Computer Modeling for Searching Conditions When the "Fable of Hares" Can Explain the Evolution of A

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14924, 2281, 13, 10159, 273, 8645, 428, 533, 368, 878, 187, 936, 320, 2119, 368, 476, 1335, 12129, 1175, 9183, 432, 3076, 9183, 13, 594, 187, 5658, 476, 626, 816, 15331, 731, 7094, 15, 187, 187, 2598, 326, 5644, 441, 281, 253, 4499, 875, 1127, 1852, 20, 13, 1053, 626, 2406, 20252, 187, 1676, 2196, 13, 285, 253, 6452, 428, 247, 1332, 273, 2820, 281, 755, 1805, 1543, 432, 187, 43408, 2793, 6095, 672, 20252, 15, 27669, 1175, 1543, 432, 1679, 187, 38835, 310, 7964, 1633, 1774, 285, 4217, 13, 533, 1679, 2793, 187, 14, 261, 14, 247, 2406, 2629, 13, 594, 309, 1158, 253, 954, 4722, 9400, 310, 627, 15, 1680, 187, 13060, 272, 952, 275, 48109, 2143, 1663, 2217, 273, 271, 4503, 6081, 2429, 281, 187, 10526, 273, 2793, 32, 1359, 1057, 352, 7277, 281, 3515, 271, 4184, 390, 820, 14, 412, 187, 14996, 32, 1680, 627, 667, 1895, 342, 253, 24834, 38287, 2970, 10166, 327, 187, 38, 1641, 90, 434, 277, 553, 533, 2444, 323, 247, 32048, 32, 1359, 310, 48109, 2143, 187, 19623, 16, 29266, 685, 2444, 342, 247, 1980, 9835, 32, 187, 187, 6223, 187, 10629, 2211, 187, 3, 28240, 1135, 7551, 8645, 44720, 449, 659, 456, 671, 347, 346, 30436, 621, 1754, 327, 187, 38835, 449, 187, 187, 34214, 4360, 671, 346, 30436, 621, 1754, 327, 2793, 326, 17343, 581, 434, 13919, 187, 527, 22947, 83, 1515, 275, 40241, 40122, 285, 3103, 17337, 11216, 1345, 33728, 318, 449, 187, 187, 6223, 187, 39923, 5432, 187, 510, 7936, 1895, 342, 954, 44720, 310, 326, 627, 310, 3839, 1199, 187, 3062, 1491, 2130, 407, 7004, 253, 2060, 15, 187, 187, 909, 15, 7820, 273, 7384, 2255, 403, 625, 11518, 13, 816, 1642, 253, 795, 68, 33524, 64, 187, 13, 1642, 3533, 8704, 616, 2495, 6222, 15, 187, 187, 2512, 403, 1270, 5657, 581, 476, 897, 432, 253, 15065, 4491, 281, 2939, 271, 187, 27276, 84, 2495, 6222, 285, 40637, 271, 8410, 5522, 326, 16382, 616, 187, 14729, 15, 3808, 9183, 751, 4266, 313, 66, 5599, 10, 971, 625, 673, 745, 984, 359, 1871, 187, 30786, 6947, 673, 342, 2021, 685, 12425, 15, 187, 187, 2042, 368, 476, 2794, 247, 27846, 789, 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1159, 15, 496, 436, 1083, 13, 352, 2506, 626, 2647, 1880, 368, 897, 26706, 329, 187, 263, 26706, 378, 15, 187, 187, 6436, 13, 275, 253, 1524, 1533, 13, 368, 452, 271, 35180, 10499, 1159, 15, 21882, 326, 187, 262, 4245, 368, 271, 3662, 2112, 247, 2622, 3268, 342, 690, 2629, 187, 3620, 2492, 15, 187, 187, 10795, 436, 1056, 253, 1083, 323, 26706, 329, 390, 26706, 378, 1027, 32, 6279, 13, 368, 1833, 452, 187, 3062, 5261, 18145, 2965, 1561, 8150, 1972, 604, 368, 760, 897, 26706, 329, 15, 187, 187, 1992, 2007, 3157, 253, 1566, 13, 368, 651, 971, 281, 871, 253, 18235, 2105, 273, 187, 5302, 271, 30833, 25180, 26706, 285, 253, 6186, 14, 36478, 4815, 3206, 275, 760, 187, 5302, 5261, 18145, 273, 1511, 329, 15, 380, 1543, 273, 253, 13757, 1895, 651, 2028, 187, 5658, 849, 1199, 273, 26706, 329, 7147, 26706, 378, 281, 897, 15, 187, 187, 4485, 187, 73, 48079, 187, 4374, 13, 9991, 310, 1774, 15, 187, 187, 6436, 13, 604, 368, 403, 1512, 7106, 327, 20252, 5343, 19414, 13, 368, 476, 3324, 253, 187, 1189, 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in-angiotensin system plays a more active role in coarctation than previously believed.The pattern of food and mortality in Belgium. Belgians have been gradually shifting from a low ratio of polyunsaturated/saturated fat in their food to a higher one with lower total fat and cholesterol. This has occurred predominantly in the north, where the most obvious change is a decrease in butter consumption and an increase in margarine consumption. The northerners have a four to five times smaller intake of butter than the southerners and nearly double the intake of margarine. Evidence gathered over the past ten years reveals in the north a decreasing serum-cholesterol and in the south a significantly higher serum-cholesterol, associated with higher coronary morbidity and mortality. Life expectancy of males in the north is 2-4 years higher at birth and 2-2 years higher at the age of 30. It is concluded that the food habits of a population can be changed, with great benefit.As ordered reported by the Senate Committee on Veterans’ Affairs on September 12, 2012 S. 2241 would provide additional education benefits to the spouses of servicemembers who died while serving on active duty. The bill also would ensure that veterans, servicemembers, and their dependents receive specific information about educational institutions and other education-related information when using their education benefits and make changes to how the Department of Veterans Affairs (VA) and the Department of Defense (DoD) administer their education benefit programs. As posted on the Web site of the U.S. House of Representatives on December 29, 2012 A bill to provide a one-year extension of the Food, Conservation, and Energy Act of 2008 and amendments made by that Act, with certain modifications and exceptions, to provide supplemental agricultural disaster assistance, to establish dairy producer margin protection and dairy market stabilization programs, and for other purposes.Taking Eden - Issue 10 A physical copy of Issue 10 will be mailed to you. SHIPPING NOTE: I use flat rate shipping through USPS. It is expensive for 1 or two issues, but please note that it does not go up, if you buy more books. A single book would still cost $4 to ship, but would go up with more items. The flat rate shipping is the best deal that I could find for you. Taking Eden - Issue 10 Taking Eden - Issue 10 4.99 A physical copy of Issue 10 will be mailed to you. SHIPPING NOTE: I use flat rate shipping through USPS. It is expensive for 1 or two issues, but please note that it does not go up, if you buy more books. A single book would still cost $4 to ship, but would go up with more items. The flat rate shipping is the best deal that I could find for you. Quantity: Add To Cart Marnie is a naive small town girl lost in the big city club scene. She worked two summers at the local Frosty Cream to save enough money to move to the big city. Staying with her cousin Jasmine, a gothic DJ, she becomes an unwitting part of a unique drug culture. Sky, the owner of multiple night clubs, along with his minions, David and Crystal, are abducting young women. They are using magic to extract their innocence which they process into a designer drug called ‘Eden’. They will stop at nothing to keep a steady stream of product moving to their high profile clientele. When Marnie crosses paths with Sky, will she be able to resist his charm and the excitement of a lifestyle she never imagined?The Commonwealth's low-interest loans proposal for debt-stricken farmers is poorly thought out and unfair, a Budget Estimates hearing has been told. The Federal Government has allocated $60 million over two years for each of the states and the Northern Territory, if they sign up to the Commonwealth's Farm Finance package. But NSW Nationals Senator Fiona Nash has used Budget Estimates to attack the Government's decision to allocate equal funds for each state. "How am I going to feel in NSW, where there are around 43,000 farming businesses, compared with the Northern Territory that's got 522, when there's $30 million on offer for each (over two years)? How am I going to feel in NSW if I desperately wanted to access this and really needed to, and I've hit the cap?" Senator Nash said. "What's that [equate to]? Forty-six farmers out of NSW, 0.1 per cent, compared to the Northern Territory with 522 farmers? How stupid a decision is that?" In addition to the $420 million concessional loans package, the Farm Finance proposal would include changes to make the Farm Management Deposit scheme more accessible, 17 more Rural Financial Counsellors nation-wide, and a promise of debt mediation reform. Federal Agriculture Minister Joe Ludwig says it's an important program that will alleviate the acute debt stress in rural Australia, and once the states sign up, the details of the package will be able to be finalised. How Etsy Grew their Number of Female Engineers by Almost 500% in One Year - bberson http://firstround.com/article/How-Etsy-Grew-their-Number-of-Female-Engineers-by-500-in-One-Year ====== pkteison I'm disappointed that "Key Reality" #2 and #4 in an article about addressing a gender related issue are both unsupported gender stereotypes. Those points could just as easily say 'people' instead of 'women', and as near as I can tell be just as true. I'm quite willing to believe that "People" tend to be conservative about switching jobs, especially if they've had a negative experience in the past. And I can see tech interviews set up "people" for failure; but I don't see anything specific to women in that, unless you want to start from some really negative stereotypes. Working on those issues will probably help your offer acceptance rate, regardless of gender - but you need to be sure you can still distinguish good candidates from bad candidates, so you can't just toss them entirely. So that leads us to the contrast between point #3, don't lower hiring standards, and the conclusion - a method of trying to get better results from reduced experience requirements when hiring. Getting good results from less experience is definitely something important and useful, but less experience -is- a lower standard, so I think the most interesting topic is there. Is watching people in hacker school really enough of an equalizer compared to years of experience? How does it compare to running an intern or co-op program? Is there any problem with the sponsored hackers getting trained on Etsy's dime but working for a competitor? How is hacker school different/better than working with a local university? ~~~ schoper "Unsupported gender stereotypes." Stated also as "opinions based on experience." Possibly also "opinions based on experience that contradict one's equality indoctrination in kindergarten and therefore deserve loud public indignation." ~~~ fleitz The fundamental problem with most stereotypes is that there is generally much more information available by asking the individual. eg. Instead of assuming women are more conservative, just ask the _candidate_ , ask questions surrounding their risk profile. There are great tools one can use from the finance industry to assess an individuals risk profile and tailor an employment package that meets their profile. Some candidates like myself (a guy) want more time off because we'd rather spend time with family than coding. If you can create a tailored work environment you'll have no problem attracting talent that's diverse, instead of just a bunch of people who like to work 80 hours a week. If you offer one size fits all employment you will hire people only for who that size fits. If you offer bespoke employment you'll hire bespoke individuals. ~~~ schoper In a world of perfect information, that would work. In a Bayesian world (ours), it doesn't work. Say that you have two types of widgets, widget A and widget B. Both have tolerances that fall along the same normal distribution but with different means. The mean for widget A is off by 0.1mm, and the mean for widget B is off by 0.2 mm. Now, say that you measure each widget before accepting it, using a perfect measuring function. In this case, it doesn't matter whether you use widget A or widget B. However, in the real world, you have an imperfect measuring function. Say that it gives you an answer along a normal distribution with some standard deviation. Does this make the case for widget A or widget B different? Yes, you'll have more widgets fall within tolerances if you only use widget A. To further improve the model, you would want to know the rejection cost of using an incorrectly sized widget and the supply-demand costs involved in only using widgets of type A. The results of the optimization problem would tell you how much of widget A versus widget B to use. ------ hjay Yes, diversity is important. However, if you are too focused on hiring female engineers, you can bring the overall quality of the team down. Now I do not mean female engineers are any less competent compared to male engineers, but I will give an example from personal experience. The

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mainlanders lacked values. That owner, my mother said, stirred rat meat into the ground pork; when you unwrapped the butcher paper, you might catch a faint scent of urine. Pork, in turn, was passed off as beef with a squirt of red dye. So she shopped at a Korean store no bigger than our garage, blocking pinched aisles to ponder the mystery of Korean packaging, while I snuck promising foods into the cart: purple rice, tofu that came in a squeezable tube, a can of what looked like shiny pretzels but turned out to be candied lotus root. At the end of winter, my mother and I made our first visit to the store since Ruby had died. Six weeks had passed. Halley's Comet had been visible as a smudge. It was to return bigger and brighter in 2061, but which of us would be alive to see it? Our aliveness was precarious. Divers had found the crew compartment of the _Challenger_ with all of the bodies inside. Soon the wreckage would reveal that four emergency air packs had been activated; not all of them had died instantaneously. At the grocery store my mother stood in an aisle and stared at the bottled vinegar. She walked the length of the display, following the spectrum from clear to black, and then stood staring at the blackest vinegar. We left the store without buying a thing. She pulled off the road and parked. In a series of actions that startled me, she hopped a guardrail, scampered across the forbidden railroad tracks, and led me down to a huge rock at the beginning of the mudflats. The rock was shaped like a fist, knuckles down. Standing on the rock, towering over the low beach, she said she was trying to listen to it speak, the water, but she couldn't hear it from there. The tide was low; the mudflats were vast. Across the rippled terrain was the same ocean she'd grown up beside; here was Turnagain Arm, which was part of Cook Inlet, which was part of the Pacific Ocean. If you cut a slanted path through the water, she said, you could end up on the eastern shores of Taiwan. Her village, even. You could stagger to land as the first light broke, coming in with the fishermen who'd just climbed down from their anchored boats. They dragged swollen nets of fish behind them on Styrofoam flats. As they came to shore in their rubber waders and boots, long squeaks marked the rhythm of their walking. On the sand, in early light, my mother waited for her father with a bamboo pole. They'd string the net over the pole and carry the fish between them. The short beach was sloped upward, so she walked at the front, and the load was easier on her. My mother climbed off the rock and tested the hardness of the silt. These days, the sun was setting during dinner; we watched each other chewing and gulping in coppery light. In a couple of months the sun would be glowing in electric perimeters around our blinds into evening. Giving us all a charge. The previous summer, Ruby had insisted she was a fish, and my mother had fed her huge sheets of dried seaweed, folding and crumpling them into her mouth. Pei-Pei had asked to go camping with her friends. Camping! my mother exclaimed. Here, where black bears lumbered down from the Chugach Mountains, gorged on salmon at Campbell Creek, and then stuck around to swipe at your garbage cans. Beyond a scrawny, twisted tree was a huge white boulder at the edge of the water. A person was squatting beside it. "My heavens," my mother said, and started running. I tried to grab the bottom edge of her coat, but caught nothing, which made my hands feel empty. We ran past the tumbling of rocks and stray driftwood and made our way toward the boulder. For a while we followed the arcing tracks of a bird, stamped into the silt, a trail of half asterisks. It was a whale, and my first impression of it was its whiteness, unsullied. It was nearly as long as my father's pickup truck, lying in a puddle. The slump of its body came up to the chest of the squatting man, who stood up. "It's still alive," he called to us. "Bleached," I thought he said, but of course he must have said, "Beached." "What is it?" my mother asked, though she knew about the belugas in Cook Inlet. On certain stretches of Seward Highway she told us to watch the water for their writhing bodies, whiter than the crests of the waves. Just once I'd seen a short, misty spray. But she didn't know how to make conversation in English. She was always asking, What time is it?—with her watch curled in her coat pocket. "Beluga," he nearly sang, and each strange syllable was liquid and warm. The man was short, with a wide, deep chest and arms so muscular they hung away from his sides. He was wearing a neon-orange cap with earflaps, from which a few gray curls escaped. I'd never seen such a funny hat, or such a happy color. My mother approached the whale and stopped two yards from its face. I hurried to her. The whale was situated in a crevice of mud and was wriggling its head side to side. I froze in the steady gaze of its small, oily black eye, not so much bigger than a human eye, embedded in a thick ring of skin. The protruding forehead and long mouth gave it a strange expression—a pained smile—as though we'd asked, Shouldn't you be in the water? "Go back," the man said. "It's dangerous, this glacial silt." "Is okay," my mother said, and tapped the toe of her loafer against the ground. When nothing happened, she dug her toe in harder. The whale lifted its head and slapped it back down. There was a cool, silty splatter on my arm. "Oh," my mother said, delighted. Her sweatpants were streaked. Its flippers pressed against the silt and its flukes fanned the air twice. The heft of its midsection was too great for it to do more than flex. Here is a whale, I told myself, and then I wondered if it would die. It looked too big to die, too big to vanish during a sudden, silent creak of the world. And what, I thought, had they done with Ruby's body? The man scratched his bristly neck and flicked the brim of his cap up. "Best she can do is stay still and wait for the tide to come back in." My mother sprang forward, and with a shock I saw her put her hands on the body of the whale. She ducked her head and shoved, arms locked straight, her loafers gouging tracks into the packed silt. Her feet slid out of her shoes. Her socks darkened where they soaked up water. The man belted out a laugh. "That's, like, two tons you're trying to roll." My mother's face hovered beside the blowhole, from which a milky foam was leaking. She slipped her shoes back on and walked around to stand before the whale's face. She touched its forehead bump, the same gesture as when she pressed a palm to our sternums to put us to sleep at night. Pei-Pei, me, Natty. "Sleep," she would say. And, so quietly we could barely hear, "Wake up again tomorrow." The heavy weight of her hand, like sleep itself bearing down on us, paralyzing us where we lay. "Come here," she said to me now. She lifted my hand to the whale's forehead. It was not especially cold or warm. The skin had a rough, porous texture, and behind the skin its flesh was soft, like a ripe peach; I could have left dents with my fingers. I don't know what kind of expression I made, but the man, a yard away, started laughing again. "This kid," he said. I liked the way he laughed, upward, without self-consciousness. He swept an arm back the way we had come. "Nothing to be done. We should get out of here." My mother did not move. She was staring hard at the whale, which began exerting more effort, its head and extremities whapping against the ground. "Do you understand what I'm saying?" His voice sounded far behind me, and when I felt his hand on my shoulder, I started and flung it off. "Easy. Does your ma speak English?" The wind lifted my mother's permed hair into a mane, making her taller and more savage. "Do you? English? Hey, kid. English?" I looked up. A neat mustache hid half his mouth, and his eyes were translucent. "What's your name?" he asked. "Gavin," I said. "How would you spell that in English?" My mother kicked off her shoes. She peeled off her wet socks, rolling them into a single ball that she stuffed into her coat pocket. She picked up her loafers, one in each hand. Immediately I wanted

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angry, orange baby that delights spectators as it travels around the world will fly again — right here in Florida. “We plan to win with love, and we LOVE Baby Trump,” said Ida Eskamani, organizer of Win With Love, in a recent statement. “The Baby Trump balloon has become an internationally recognized symbol of President Trump’s regular temper tantrums that endanger this country and our desperate need for an adult in the White House. It is also a symbol of resilience; in the midst of darkness, we can find joy in a giant, inflatable baby. We’re ready to bring Baby Trump to Orlando.” The event which takes place strategically on the evening before Juneteenth, a celebration of the end of slavery, also falls between the 3-year anniversary of the Pulse massacre, and just before the 50th anniversary of the New York City Stonewall Riots. Organizers are currently accepting donations to make the event more accessible and provide interpretation services. The balloon, which originated in the U.K. in 2018 when it flew over Parliament Square in London during an official visit by the president, has been spotted internationally in Ireland, Argentina and France, as well as at various locations in the U.S. according to Wikipedia. This will be the balloon’s first time taking to the warm summer air in Orlando, but it has been viewed in Florida before, near the location of Trump’s Mar-a-Lago resort. For more information about the Win With Love Rally visit the Facebook event page.The Flash: Matt Letscher returning as Reverse-Flash The Flash type TV Show network The CW genre Superhero Where to watch Close Streaming Options From now until our winter TV preview hits newsstands Jan. 15, EW is bringing you 25 scoops in 25 days. Follow the hashtag #25Scoops25Days on Twitter and Instagram to keep up with the latest, and check EW.com/25Scoops25Days for all the news and surprises. As if Barry Allen didn’t have enough on his plate with villain Zoom wrecking havoc on Central City, now he’ll have another speedster to contend with in the new year: Reverse-Flash! No, we’re not talking about Tom Cavanagh yellow-suiting it up once again. EW has learned exclusively that Matt Letscher will be returning to The Flash as Barry’s nemesis, Eobard Thawne, otherwise known as the Reverse-Flash. WANT MORE EW? Subscribe now to keep up with the latest in movies, television, and music. A brief refresher from last season: Letscher’s Eobard Thawne traveled back in time and killed Barry’s (Grant Gustin) mother before getting trapped in that era. Eobard then absorbed Harrison Wells’ (Cavanagh) DNA to take on his persona, and trained Barry to be fast enough to tap into the Speed Force so he could return home. But his ancestor Eddie Thawne (Rick Cosnett) killed himself, effectively erasing Eobard from the timeline. So, considering the original Reverse-Flash met his maker last season, we may be looking at a speedster from a different Earth. Here’s what executive producer Todd Helbing, who penned the episode featuring Letscher’s return with Aaron Helbing, would reveal: “His impossible return to Central City puts a member of the S.T.A.R. Labs team in unexpected danger, forcing Barry to make a life-changing decision.” Letscher (Scandal, The Carrie Diaries) is slated to appear in episode 211, which is fittingly titled “The Reverse-Flash Returns.” The Flash returns Tuesday, Jan. 19 at 8 p.m. ET on The CW.misterhouse-users I just recently started using MH, everything works good that I have configured so far. The question I have is, I use x10 devices to control some stuff around the house, mainly just lights for now(using LM15A) . I use the CM17(and RR501 Remote module) & CM11 to control the various items. The problem I have is this, in the kids room is a HR12A Powerhouse controler that the kids can use to control lights until i get some more feature such as audrys added, but is there a way to check , lets say every 10 minutes to find out what the current status of the x10 devices are? and adjust MH so it know if the kids turned a light on or off using the remote. Thnx Dick Bradford -- No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.1.405 / Virus Database: 268.12.8/455 - Release Date: 9/22/2006 I am currently using CM11 & CM17 to control my X10 devices, but I am having the hardest time with them, So far this year I have killed 2 CM17's ... Not quite sure why, but is there any type of interfaces that are compatible with MH that can control X10 devices and have a better life span? other than the CM11 ? Thnx Dickie -- No virus found in this outgoing message. Checked by AVG Free Edition. Version: 7.1.409 / Virus Database: 268.13.31/522 - Release Date: 11/7/2006 Dickie- I recently picked up an ACT x10 interface on sale from smarthomeusa, but haven't had time to set it up and test it out. I guess I've been really lucky because my cm11 has been working fine for a number of years. I got this primarily as a backup unit, but plan on testing it out soon. I'll report back as soon as I have some info. Joel On Tue, 7 Nov 2006, it would appear that Dickie Bradford wrote: > I am currently using CM11 & CM17 to control my X10 devices, but I am having > the hardest time with them, So far this year I have killed 2 CM17's ... Not > quite sure why, but is there any type of interfaces that are compatible with > MH that can control X10 devices and have a better life span? other than the > CM11 ? > > Thnx > > Dickie The LM15a is not a 2 way device, so you cannot directly find out if the light has been turned on/off. HOWEVER, if they are using the remote to turn them on / off, then you can simply assign the devices to MH via the CM11 and it will automatically synchronize its state every time a button is pushed (as long as MH is running when the button is pushed). Hope that helps, -J On Sun, 24 Sep 2006, Dickie Bradford wrote: > I just recently started using MH, everything works good that I have > configured so far. > > The question I have is, I use x10 devices to control some stuff around the > house, mainly just lights for now(using LM15A) . I use the CM17(and RR501 > Remote module) & CM11 to control the various items. The problem I have is > this, in the kids room is a HR12A Powerhouse controler that the kids can > use to control lights until i get some more feature such as audrys added, > but is there a way to check , lets say every 10 minutes to find out what the > current status of the x10 devices are? and adjust MH so it know if the kids > turned a light on or off using the remote. > > Thnx > > Dick Bradford > > > > > -- > No virus found in this outgoing message. > Checked by AVG Free Edition. > Version: 7.1.405 / Virus Database: 268.12.8/455 - Release Date: 9/22/2006 > > > ------------------------------------------------------------------------- > Take Surveys. Earn Cash. Influence the Future of IT > Join SourceForge.net's Techsay panel and you'll get the chance to share your > opinions on IT & business topics through brief surveys -- and earn cash > http://www.techsay.com/default.php?page=join.php&p=sourceforge&CID=DEVDEV > ________________________________________________________ > To unsubscribe from this list, go to: http://sourceforge.net/mail/?group_id=1365 > > > I am trying to update the Light objects with UPB so that when instantiated they synchronize with the item they are representing. I was wondering what is used to request an update from the X10/Insteon device, so I can make that universal. So far in UPB lingo, this is requested currently with: $upb_light->set("report"); which triggers the device to send back its current state and the underlying object receives this and sets it state accordingly. I know the X10SW and Insteon must have something similar and was wondering what that is (I dont recall how the X10SW did that) -J Thnx for the info J would you happen to have a working example i could go by? or point me to where I might find one?

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271, 9592, 21198, 1824, 7563, 13, 285, 2779, 625, 12848, 390, 1014, 3710, 9313, 14, 22210, 17177, 11026, 313, 46840, 7184, 1162, 355, 15, 1008, 1311, 1610, 1092, 1535, 79, 4530, 1162, 355, 15, 1008, 1311, 1671, 2498, 187, 187, 4041, 1364, 671, 4456, 326, 8588, 2515, 13, 275, 1798, 253, 5927, 2329, 3276, 347, 973, 347, 9559, 16958, 13, 403, 8127, 7976, 327, 1980, 2515, 313, 70, 15, 72, 904, 34724, 19781, 84, 10, 313, 54, 1344, 79, 335, 1162, 355, 15, 1008, 1311, 1787, 2498, 19926, 5829, 1079, 1783, 323, 16795, 285, 697, 2067, 5799, 4811, 13, 534, 403, 4942, 6447, 275, 8609, 2426, 13, 2167, 12848, 39331, 13, 1057, 417, 2085, 247, 2590, 3662, 342, 1675, 281, 13554, 387, 253, 1980, 1268, 15, 187, 187, 1552, 789, 369, 4516, 407, 253, 2199, 27, 24819, 2196, 271, 41275, 25780, 323, 28678, 15836, 29930, 2903, 405, 942, 323, 5625, 15111, 13869, 342, 8057, 14, 18919, 11401, 942, 13, 3313, 6875, 6807, 330, 17659, 11240, 1621, 15, 470, 28766, 25139, 15, 187, 60, 34, 2554, 273, 24109, 14, 882, 267, 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dates) at selected stations representing fruit-growing regions in Poland (1951--2010) In the central-north region of Poland, the upward trend associated with local heat resources is accompanied by a small, but statistically significant, change in the occurrence of spring frost. For example, in Skierniewice, frost can be expected less than 2 days in advance (Fig. [6](#Fig6){ref-type="fig"}), with a trend of GDD totals of 42.1/10 years. The lowest *T* ~min~ values during the plant growth period (GDD ≥ 150) may reach −3.0 °C. The central-southern and western regions of Poland are characterized by frost periods ending increasingly early (in both cases---Sandomierz and Opole stations---\>2 days/10 years), with a significant increase in thermal resources (respectively: 29.5 and 51.9 GDD/10 years) (Fig. [6](#Fig6){ref-type="fig"}). The lowest minimum temperature during the growing season, after exceeding the threshold of GDD = 150, was −1.9 °C in Sandomierz, while in Opole, it was −2.8 °C. The lowest minimum temperature value for the remaining thresholds was −0.8 °C. Conclusions {#Sec8} =========== Global studies on climate change impacts on agriculture, horticulture, and forestry confirm unanimously that an increase in the length of the growing season followed by a higher amount of thermal resources may enhance crop production at mid- and high latitudes, and increase potential output at harvest time as well as improve forest productivity (Winkler et al. [@CR40], Linderholm et al. [@CR21], Trnka et al. [@CR35]). However, the rate of the observed changes may have a large impact on already living species' distribution and the spread of insects, as well as may affect grain yields and crop seed production (Winkler et al. [@CR40], Thuiller et al. [@CR34]). Moreover, the increase in heat accumulation at the time of the last spring frost event as well as the variability of the frequency of frost events after sensitive plant growth stages is reached either maintains or increases frost risk (Winkler et al. [@CR40], Trnka et al. [@CR35]). Although the research conducted so far for the territory of Poland has confirmed, as already stated, both global and regional tendencies, it was carried out only for selected stations with limited representativeness. Therefore, the results cannot be fully applied to the whole area of Poland. The use of a gridded database in the current analysis assures continuous information on temperature differentiation and provides a fairly clear picture of GDD value variability in Poland. Furthermore, it combines a thorough characterization of thermal resources across the country with frost risk analysis for several different spring phenophases expressed by GDD accumulation, with a special focus on the main fruit-growing regions of the country. A statistically significant increase in average annual air temperature (about 0.2 °C/10 years), manifesting itself in a temperature rise in the spring months (about 0.4 °C/10 years) and in an extension of the growing season by an average of 2.5 days/10 years, has been observed. The trends described in the study result in an increase in heat resources with the greatest intensity between 0 and 5 °C (*T* ~base~ 0 °C). The changes most clearly described above are observed in the southern and southwestern regions of Poland, which are considered to be warmer regions. Future projections simulated up to 2090 give a clear image of an increase in thermal resources in Poland following changes in the length of the frost-free and growing seasons. Despite the implications of the aforesaid climate model, these thermal changes appear to be favorable for agriculture (Graczyk and Kundzewicz [@CR14]). Taking into account the results of phenological studies confirming that an increase in air temperature by 1 °C per year accelerates the growth of plants by 2 to 5 days, and by a dozen or so days, when the increase in thermal resources concerns the spring period (i.a. Chmielewski and Rötzer [@CR8]; Menzel et al. [@CR25]; Jatczak and Walawender [@CR18]), one may assume that the development of horticulture in Poland is possible with respect to the introduction of new thermophilic varieties or even new species. However, it has to be pointed out that these are hydrothermal conditions that drive crop yields and quality. Poland's continental climate zone at middle latitudes faces significant interannual variability of precipitation amounts and water deficits, especially in the summer as a result (Trnka et al. [@CR35]). Most of Poland features negative climatic water balance summer values (Wypych and Ustrnul [@CR42]), which results in a decrease in water storage and summer water shortages (Szwed et al. [@CR33]). Projected evapotranspiration intensity, driven primarily by additional temperature growth, will lead to an increasingly stressed water budget, and likely more varied or even limited rain-fed crop yields (Szwed et al. [@CR33], Trnka et al. [@CR35]). One must also remember that weather conditions, in particular the minimum air temperature as well as extreme phenomena, are largely dependent on local conditions (e.g., frost hollows) (Ustrnul et al. [@CR37]). Mesoscale analysis for Poland and its several distinct regions, which are relatively uniform in thermal terms, though varied environmentally, does not provide a clear answer with respect to trends at the local level. This work was supported by the project: Towards an Integrated Framework for Climate Change Impact Assessments for International Market Systems with Long-Term Investments, National Science Foundation CNH Award No. 0909378. [A role of peri-ictal SPECT for the identification of epileptogenic focus]. A 42-year-old man had complex partial epilepsy and secondary generalized seizure, without remarkable abnormalities in interictal EEG and head MRI. Three-dimensional SRT (3D SRT) analysis of peri-ictal SPECT data detected hyperperfusion in the right temporal lobe, the basal nucleus and the hippocampus, which showed hypoperfusion during interictal period. These findings suggested that the epileptogenic focus existed in the right temporal lobe. We concluded that 3D SRT analysis of peri-ictal SPECT would be helpful to identify the epileptogenic focus.Q: push is not working on the controller which was presented modally Hello I have a button on FirstViewController and I dragged a segue from firstViewController to secondViewController as segue Modally. Now on the secondViewController I am generating a Button Programmatically and to go on the third controller I am pushing the controller(segue Push) But its not working. thirdcontroller doesn't comes up. Nothing happening when I click the custom button. Here is the secondViewController code func nextButtonClicked(sender:UIButton!){ let takeProductPhotoController = self.storyboard!.instantiateViewControllerWithIdentifier("takeProductPhotoController") as! TakeProductPhotoController takeProductPhotoController.trip = trip self.navigationController?.pushViewController(takeProductPhotoController, animated: true) } Note: I don't need the NavigationBar on Second View Controller so while presenting it modally it didn't show the navigationBar. But I need the navigationBar on the third one. So thats why I am pushing in naviagtioncontroller A: Whenever you want push from the popped controller you have to creat the new NavigationController & also set the ViewController which you want to present modaly as rootViewController of navigationController. When we want to present the SecondViewcontrollermodally, We are presenting navigation controller with rootViewController set to SecondViewController. So we have created the new navigation stack. After that we are going to push the controller in the new navigation stack created while presenting SecondViewController. 1) Your code should be look like this in FirstViewController let secondViewController = UIStoryboard(name: "Main", bundle: nil).instantiateViewControllerWithIdentifier("aIdentifier") as! SecondViewController let nav = UINavigationController(rootViewController: SecondViewController ) self.presentViewController(nav, animated:true, completion:nil) 2) From secondViewController you can push ThirdViewController in self.naviagtionController. Write below code in SecondViewController on Button Action let thirdViewController = UIStoryboard(name: "Main", bundle: nil).instantiateViewControllerWithIdentifier("cIdentifier") as! ThirdViewController self.navigationController?.pushViewController(thirdViewController , animated: true)} import hashlib from lib.core.settings import LOGGER class HashCracker(object): results = {} cracked = False def __init__(self, hash, wordlist=open("lib/text_files/wordlist.txt").readlines(), type=None): self.hash = hash self.words = wordlist self.type = type def try_all_algorithms(self): """ Try every algorithm available on the computer using the 'algorithms_available' functions from hashlib an example of this functions would be: >>> print(hashlib.algorithms_available) set(['

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refrigerant is deposited on the exterior surfaces of some of the heat transfer tubes in the tube bundle and the other heat transfer tubes in the tube bundle are immersed in the liquid refrigerant that has been collected at the bottom portion of the shell. Although the flooded evaporators exhibit high heat transfer performance, the flooded evaporators require a considerable amount of refrigerant because the heat transfer tubes are immersed in a pool of the liquid refrigerant. With the recent development of new and high-cost refrigerant having a much lower global warming potential (such as R1234ze or R1234yf), it is desirable to reduce the refrigerant charge in the evaporator. The main advantage of the falling film evaporators is that the refrigerant charge can be reduced while ensuring good heat transfer performance. Therefore, the falling film evaporators have a significant potential to replace the flooded evaporators in large refrigeration systems. Regardless of the type of evaporator, e.g., flooded, falling film, or hybrid, a distributor is provided to distribute refrigerant entering the evaporator to the tube bundle. U.S patent publication No. 2015/0053378 discloses one example of such a distributor. The distributor is designed to separate vapor refrigerant from liquid refrigerant and distribute liquid refrigerant toward the tube bundle. Particularly in the case of a falling film type evaporator such distribution is desired. Google is Crushing the Internet - dforrestwilson http://theweek.com/articles/693488/google-monopoly--crushing-internet ====== empath75 I don't have a strong opinion about whether or not google should be regulated or not. However, this guy doesn't seem appreciate the scale of the difficulties that google solved and how much better google was than the competition. They almost single-handedly transformed the internet into a useful tool. Altavista and yahoo were like looking up information in a card catalog in comparison. It wasn't just a first mover advantage. And they followed it up by releasing, an ads platform that made everyone else look like amateur hour, a mail product that was far better than hotmail, a mapping tool much better than MapQuest, and a web browser that was far better than ie or Firefox. They are in the position they're in because they solved a lot of difficult problems and made it look easy. If we ever get to the point that we need as a society to rein them in, we should do it with a full understanding of what they've accomplished. It's bizarre to accuse the company that made the internet into what it is today of somehow crushing it. ~~~ wazoox Basically you're explaining that they earned a monopoly for a reason. That's true. And there are always true advantages to monopoly (standardization, economy of scale, prices stability ...). However monopolies harm the economy and the public good in the long run. See, that works for any past monopoly: I don't have a strong opinion about whether or not Microsoft should be regulated or not. [...] It's bizarre to accuse the company that made the PC into what it is today of somehow crushing it. I don't have a strong opinion about whether or not AT&T should be regulated or not. [...] It's bizarre to accuse the company that made the telephone into what it is today of somehow crushing it. I don't have a strong opinion about whether or not Standard Oil should be regulated or not. [...] It's bizarre to accuse the company that made the oil industry into what it is today of somehow crushing it. ~~~ bgw It has always been strange for me to understand Google search as a monopoly. First, there are competitors. Second, it's free (yes, I know you pay with data). Third, you can use the internet without using any of Google's services (except adsense, I suppose). How is Google's search a monopoly when it's the user who is deciding they prefer it to Bing or Duck Duck Go or Yahoo? Perhaps my understanding of monopoly is incomplete because this makes no sense to me. ~~~ pixl97 If I produce content that I want other people to view, I have to cater it to googles requirements or almost nobody sees it. Simply put Google is the biggest driver of traffic and ad dollars. If you play by (or if you game) Googles rules you can make piles of cash, driven by the traffic they send your way. Then the next day it can dry up with no reason given. Saying that the user prefers it is a slightly backward way of thinking about it. Does the user prefer it because it is better, or is it because abuse of their monopoly doesn't allow other providers to achieve the same quality of service? ~~~ scarface74 _If I produce content that I want other people to view, I have to cater it to googles requirements or almost nobody sees it. Simply put Google is the biggest driver of traffic and ad dollars._ I know of a few bloggers who don't seem to be dependent on Google or Facebook to maintain their business. 1\. John Gruber (daringireball.com). He made a name for himself over 15 years and is famous enough to be on the shortlist of people that Apple always reaches out to when they want to do a four or five person press event. He routinely gets VPs from Apple on his podcast. He sells RSS sponsorships - one at the beginning of the week and one at the end of the week. He also makes money from his podcast. He did lose half his readership after Google killed off Google Reader, but he said since he never sold his ads based on the number of readers, it hasn't hurt his business too badly. 2\. Ben Thompson (stratechery.com). He posts once a week to his blog, became popular and has over 2000 subscribers to his newsletter that he charges $100/a year for. He has one advertiser for his podcast - mailchimp - they sponsored him for an entire year. 3\. Marco Arment - first architect of Tumblr, creator of Instapaper, and now Overcast. He is also a decently well known blogger in the Apple ecosystem. He basically created his own podcast app ad sales platform, and has a popular podcast. 4\. Horace Deidu. He started out as a blogger/analyst and now he gives speeches and does workshops worldwide. It's hard getting noticed over the noise, but it can be done. It is possible to create a viable content business without an over reliance on Google. ------ 5_minutes While I understand the sympathy here for Google's accomplishments, and don't agree with many of the OP's points - just objectively, it's scary for us all to be dependent on one commercial company. Wether they earned to be in that position or not. It's also hard to compare things: the scale of the current internet usage, the type of information that is available. (And what can be influenced by showing what). This scale is much, much wider then what happened to AT&T back in the days. That said, since Apple and MS are also getting away with very similar things, I don't see a point in punishing Google. Especially, as them all being US companies. The solution of breaking up Google and then putting weaker foreign company in the front-seat, by doing so -- also would not make any sense. ------ fear91 I'm wondering when, if ever, the general public will start recognizing Google as one of the "big brothers". Somehow it's still perceived as this "cool" startup but they squash small businesses, avoid taxes, are in bed with intelligence agencies, etc. ~~~ quickben I'm old enough to remember the techies backlash over targeted advertising in Gmail. It seemed the google's PR started throwing cash at it for years to "educate" the public. The general public appeared to be a complacent herd of sheep like creatures that would embrace convenience over everything. Maybe in your circles Google is "cool". In my circles it's necessary evil. The platform/network effect is so strong there is no escaping it. The US is invested my money wise too deep and won't do what they had the backbone to do with SO and the rest. So, "when, if ever", won't be anytime soon. Meanwhile, innovation suffers. They killed chat protocols interfaces (pure monopoly abuse since they have most users), the buried end-to-end encryption, they killed bunch of competing businesses by promoting their side businesses on the search page higher, etc. Http2 could have had things for the users in it (if one goes through the troubles of upgrading a network layer). Instead it had "cut off download at instant if requested" and other features that made web crawling (though not necessarily browsing and developing) easy. Going forward, they will be cleaning the advertising agency landsccape to get rid out of competition with : Amp ( since they de facto own mobile browsing and Android). Desktop displayed ads (they announced as blocker in chrome, and guess twice whose ads will be allowed through). I can enumerate all day.

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Thoroughbred racehorse who was the champion filly of her year and beat the colts in the 1987 New Zealand Derby. After finishing second in her debut, Tidal Light won ten of her next 13 races, including the Derby, Avondale Guineas, Waikato Guineas, Canterbury Guineas and a Group 1 victory in the Air New Zealand Stakes over older horses under weight-for-age conditions, beating the great Solveig. She returned in the spring of 1987 as a four-year-old, but failed to win a race and despite some good performances was obviously not the same horse she had been the previous season. Her three-year-old season earned her both the Three Year-Old of the Year award and Horse of the Year, a rare feat for a filly. She died in March 2007. Category:1983 racehorse births Category:2007 racehorse deaths Category:Racehorses bred in New Zealand Category:Racehorses trained in New Zealand Category:Thoroughbred family 21-aA father-of-two has died days after he was stabbed multiple times in a horrific road rage attack on an Adelaide street. Troy James McLean, 34, tried to drive himself to hospital while bleeding profusely, but crashed into a parked car just metres before he got there. The owner of the car he drove into found him slumped behind the wheel when he went to confront him soon after the stabbing at 10.40am on Saturday. Benjamin Joshua George, 25, allegedly stabbed Troy James McLean to death in a horrific road rage attack on an Adelaide street McLean tried to drive himself to hospital while bleeding profusely, but crashed into a parked car just metres before he got there Mr McLean was rushed to Royal Adelaide Hospital in a serious condition and had emergency surgery while clinging to life, but died on Tuesday. Charges against Benjamin Joshua George who allegedly stabbed him during a roadside argument will be upgraded to murder. The 25-year-old allegedly stabbed him before driving off and leaving Mr McLean badly injured at a busy intersection. George begged the victim's family for forgiveness as he appeared in court on Monday, saying 'can I just say I'm sorry to everyone' Mr McLean's bloodstained car that he tried to drive to the hospital after he was stabbed He begged the victim's family for forgiveness as he appeared in court on Monday, saying 'can I just say I'm sorry to everyone', according to the Adelaide Advertiser. George was remanded in custody to face court again in January, causing his family to burst into tears as they watched from the gallery. Magistrate Yoong Fee Chin said George could apply for bail at a future court date.Field of the Invention The present invention relates to a reproducing apparatus for reproducing information from a recording medium, a program used for reproduction, and a recording medium with the program recorded. Description of the Prior Art To manage contents recorded in a recording medium, in audio-visual equipment such as CD and DVD players, a method is devised to obtain information from a recording medium itself or network and produce content information. (Refer to Japanese Patent Laid-open No. 2001-307464, for example). In recent years there has been a growing use of broadband networks. Besides information in small amounts, there are thus available more and more subtitle information for movie titles and more and more diversified contents such as images and audio.Scotland’s largest independent courier has bucked an industry trend of cutbacks and liquidations and is set to announce the busiest year in its 30 year history – but warns that future fuel price rises could remove any profit from low-margin public-sector contracts. With the courier industry enduring a turbulent 12 months, highlighted by the dramatic Christmas Eve demise of City Link, further industry setbacks have resulted from the cut back of many public sector contracts. Despite this, 2015 has proven to be a particularly busy period for Eagle Couriers which is on track to increase the total number of consignments delivered, breaking the one million mark for the first time in its history, with revenue also up 10 per cent on 2014. Eagle Couriers’ 100-strong fleet of drivers have so far made close to 20,000 deliveries per week, in part due to its role delivering significant public sector contracts. 2015 has also seen the firm commit to a six-figure sum move to new purpose-built headquarters in Bathgate, maintaining its bases in Edinburgh, Glasgow and Aberdeen. The new West Lothian hub was officially opened in October by Hannah Bardell, MP for Livingston and the SNP’s spokesperson for Business Innovation and Skills. Fiona Deas, Co-Director of Eagle Couriers, said: “By working tirelessly to build recognition as a reliable, efficient and adaptable service we have been able to boost turnover despite difficult economic conditions. “We have established a strong team which has provided a foundation to build on past contract successes and take on more large, often high pressure contracts knowing that we can deliver on them. “The difficulty we face now is that many contracts are being operated along very thin margins – an increase in costs such as fuel could suddenly cause huge problems in the industry. This looks set to be the biggest challenge in the coming years. “The better the firm does, the more Scottish jobs we can offer and support – as great as this is, we are in effect banking on fuel prices remaining relatively low.” The past year has seen Eagle Couriers land prestigious contracts, including the transportation and logistics behind the general election voting papers and ballot boxes and a new contract with the leading online retailer. The Bathgate business also continued sensitive and demanding work with national examination boards, organising the delivery and collection of papers from almost every school in mainland Scotland. The other Director at the helm of Eagle Couriers, Jerry Stewart, enjoyed a positive 12 months with his induction as a Fellow of the Institute of Couriers – in a ceremony at the House of Lords earlier in the year – proving to be a particular highlight. Jerry, a 30 year veteran of the sector, said: “It’s been a big year personally and has provided me with further evidence that this industry truly never stands still. “It is now essential that firms in the sector are at the forefront of technology, both in terms of the day-to-day operations and in customer service – where up to the minute parcel tracking is an expectation. “We are delighted to be able to announce such positive figures and it is a real endorsement of the hard work that has gone on behind the scenes making sure we are at the forefront of any advances. “The courier and logistics industry has changed dramatically and it has been tough at times – something that is evident with the collapse and cutbacks seen with some of our notable UK-wide competitors.” Eagle Couriers has a 3500-strong client base including the BBC and the NHS, public sector organisations and sole traders. As business-to-business experts, Eagle Couriers help other firms operate more efficiently and profitably by safely delivering on time everything from documents, medical samples and engine parts to sports footage, scripts and TV props. A total of 83,077 passengers are expected to land at the airport within five days of Christmas, about 36,000 more than at Glasgow which will be the second busiest Scottish airport. edinburghnews.scotsman.com/ne…Order filed February 15, 2018 In The Fourteenth Court of Appeals ____________ NO. 14-17-00434-CV ____________ IN THE INTEREST OF Z.Q.N., A MINOR CHILD On Appeal from the 309th District Court Harris County, Texas Trial Court Cause No. 2016-14463 ORDER The brief of appellant, L.M.B., was due February 7, 2018. No brief or motion for extension of time has been filed. Unless appellant files a brief with this court on or before March 9, 2018, the court will dismiss the appeal for want of prosecution. See Tex. R. App. P. 42.3(b). PER CURIAM .. currentmodule:: webexteamssdk ============= webexteamssdk ============= *Simple, lightweight, scalable Python API wrapper for the Webex Teams APIs* ------------------------------------------------------------------------------- Welcome to the docs! webexteamssdk is a *community developed* Pythonic wrapping of the Webex Teams APIs. The package represents all of the Cisco Webex Teams API interactions via native Python tools. Making working with the Cisco Webex Teams APIs in Python a *native* and *natural* experience. **webexteamssdk helps you get things done faster.** We take care of the API semantics, and you can focus on writing your code. With webexteamssdk, you can easily: * Interact with the Webex Teams APIs in an interactive Python session * Quickly create code that enables you get something done in Webex Teams * Leverage the API wrapper to cleanly add Webex Teams functionality to your project without having to write the boilerplate code for working with the Webex Teams APIs To *dive in* and see how webexteamssdk makes your life better, check out the :ref:`Quickstart`! The User Guide ============== .. toctree::

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Could it be a hotspot? Moses had one a few years ago that went from the size of a dime to the entire side of his face over night. Do a search on here for Moses hotspot and you can see pics and treatment recommendations. Vertericyn is handy to keep on hand. Something else to consider: Pythiosis of the skin (or cutaneous pythiosis) results in the development of swollen, non-healing wounds, and invasive masses of ulcerated pus-filled nodules and draining tracts. Tissue death (necrosis) follows, with the affected skin eventually turning black and wasting. Causes This infection is caused by direct contact with water that accommodates Pythium insidiosum, a water borne fungal parasite. It is usually swallowed or inhaled by the dog, and from there makes its way to the animal's intestinal tract. Register Now In order to be able to post messages on the German Shepherd Dog Forums forums, you must first register. Please enter your desired user name, your email address and other required details in the form below. User Name: Password Please enter a password for your user account. Note that passwords are case-sensitive. Password: Confirm Password: Email Address Please enter a valid email address for yourself. Email Address: Log-in User Name Remember Me? Password Human Verification In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.Q: Nested class AsyncTask can't modify Outer Class static objects I have a problem with Nested java class, it sees outer class object but somehow fails to modify it. I read a lot of similar questions but couldn't find solution for this one. It might be something really simple but I'm not good enough to figure it out. I have Sorter class to do some calculations in the background, I decided to use AsyncTask to perform those calculations outside of UI Thread. My class looks like this public class Sorter { private static List<Long> workingList; private static int _numberOfContainers, _containerSize, _timesToRepeat; private static Long _numbersFrom, _numbersTo, _sortingAlgorithmId; public Sorter(int numberOfContainers, int containerSize, Long numbersFrom, Long numbersTo, int timesToRepeat, Long sortingAlgorithmId) { _numberOfContainers = numberOfContainers; _containerSize = containerSize; _numbersFrom = numbersFrom; _numbersTo = numbersTo; _timesToRepeat = timesToRepeat; _sortingAlgorithmId = sortingAlgorithmId; // perform calculations in the background new BackgroundCalculations().execute(); } static class BackgroundCalculations extends AsyncTask<Void,Void,Void> { @Override protected Void doInBackground(Void... voids) { workingList = new ArrayList<>(_containerSize); // workingList is still null after this _numbersTo += 1; // to fix exclusive number range to inclusive Random rand = new Random(); for (int i = 0; i < _containerSize; i++) { workingList.add((long) (rand.nextDouble() * (_numbersTo - _numbersFrom)) + _numbersFrom)) } // some calc return null; } } } I tried to instantiate workingList in Sorter constructor but nested class fails to add items to workingList anyway. Any solutions? Maybe better way to implement background calculations without such problems? A: You are mixing up two concepts here. Your methods are all static; and your fields are two. So why do you then use a constructor; indicating that you want an object of your Sorter class to be instantiated? So, the first thing to fix your problem - get a better understanding of the concepts you are using. 515 F.2d 1181 *dMoodyv.U. S. 75-1124 UNITED STATES COURT OF APPEALS Fifth Circuit 6/25/75 1 M.D.Ga. AFFIRMED * Summary Calendar case; Rule 18, 5 Cir.; see Isbell Enterprises, Inc. v. Citizens Casualty Co. of N Q: I want to learn to play an electric guitar, how do I start? I'm 15, and recently I've watched a few electric guitar performances on YouTube. It got me really interested in electric guitars. Now, I've never played a guitar before, neither electric nor acoustic, i kind of did, I'll explain in a second. My grandfather owns a few acoustic guitars and he's pretty good at it. When i was 11 he taught me how to play Smoke on the Water, a pretty simple melody. I didn't practice that song much, I played it a few times for fun, what I'm trying to say is that I kind of know how a guitar feels on my lap and I know how it feels to play the strings. Apart from that, I never played them. I wasn't interested in guitars before, but recently I have. I don't like acoustic guitars, I like electric ones. Anyway, I have a question: I''m a beginner. I'd like to learn how to play an electric guitar. Should my first guitar be an electric or acoustic? Which one is easier to play and easier to learn to play? And a bit sillier one, could I cut my fingers on a guitar's strings? I'll be glad if someone answered my questions, I'm eager to learn how to play an electric guitar. A: I don't like acoustic guitars, i like electric ones. You should start with an electric guitar. There are arguments both ways to whether to start on electric or acoustic, but these differences are minor compared to enthusiasm. You won't get anywhere with a guitar that you don't like and don't play. You'll go far with one that gets your heart racing so you play it frequently. The strings on electric guitars are usually lighter and closer than acoustic. This is argued in favor of electrics as easier to get started on and in favor of acoustics as forcing better habits. If your grandfather is available I'd recommend taking him shopping for an inexpensive but well set up electric guitar and amp. There are dozens of sites with reviews of good starter guitars. The important thing when starting out is that it's set up well. A cheap but well set up guitar will play better and easier than an expensive but poorly set up one. Once you have the guitar take some lessons (or have your grandfather give you some if he's available and able to - playing and teaching are very different skills though) and find some like minded friends to play with. Locally a lot of the teen-oriented lessons also help the students form bands. If your friends aren't already interested in playing there may be something similar near you. Your fingers will be sore when you get started, but they shouldn't bleed. You'll need to build up strength and stamina. Take things slowly at first and stop when your fingers or hands hurt. A teacher will be able to help identify if you're hurting because of bad technique or if it's just from getting tired. Playing several 10-15 minute sessions is much safer and more valuable than one marathon session. A: Should my first guitar be an electric or acoustic? If you want to play electric, as you said, then your first guitar should definitely be an electric. Which one is easier to play and easier to learn to play? Stylistically, as in how people choose to play them, they are just a little different and neither is necessarily easier. But from a technical standpoint, assuming you chose to play the same thing on both, an electric is usually a little easier to play for most people because of the string gauge, action, and neck thickness. And a bit sillier one, could i cut my fingers on a guitar's strings? Just from playing them? No, not really. You might get blisters at first if you practice hard enough but eventually you'll build up calluses. And you can and probably will prick yourself on the strings ends at some point when changing strings. how do i start? Get a guitar Get a teacher Have them help you learn songs that you like because you'll make more progress if you're enjoying your practice time. Try to have a goal and keep that in mind at all times. For example if your goal is to play cover songs in a band with friends, then you should spend your practice time learning songs and playing with a band. But if your goal was something different you might spend your practice time on something else. Your practice time should always be moving you toward your goal. Home Theater Installer THX Home Theater 2 Professional Workshop Building upon the Home Theater 1 Workshop, this Home Theater 2 course provides in-depth training on room acoustics and design, wall treatments and isolation, and AV hardware selection and placement. Hands-on training techniques are incorporated into this comprehensive program – detailing system set up, speaker positioning and audio calibration. General Course Information The cost for this

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go go" "I'll be back." "Manager!" "Do not eat that!" "Don't" "Hello" "Having a crush, You haven't reach puberty?" "You have that opportunity today." "You could have dated her." "Come on.." "I have my way.." "It's suffocating to death watching this." "Expert.." "Why do you get dump always?" "You punk!" "Mr. Yoon.." "From my observation." "You seem too withdrawn." "Really?" "To win her over, comply to Rule 369" "Ah.. what is that?" "Three." "Text her 3 times daily." "Six." "Reply 6 mins after she replied." "Nine." "After nine at night never reply." "Ah.." "Try to look tough today." "It's Christmas eve." "You guys dating?" "Madam Jung.. take a seat" "Today I give slight concession to you." "For that I have to thank you." "Why are you late?" "What?" "Turn off fire 3 mins later." "Remember to off it after 3 minutes" "Yeah ok" "Come with me." "Onions should be peel by hands." "My precious ring." "How dare he eat it?" "Bring so many tears to me." "Oh." "Fire!" "Fire!" "What happened?" "Call your call" "All in" "Ooo..his cards must be good." "Run away." "Hold it.." "I won it." "I won." "Hurry Hurry" "Yeouido personel dispatched now." "Announcement" "Teams 7 get ready to go" "I obviously won it!" "Come over Come over" "Byung-man you coming?" "Where's that card?" "Excuse me" "I am looking for the Chief?" "Take a look" "Who you are?" "What could be the problem?" "How do you people manage this place?" "Sorry about it." "Any incident in the kitchen." "You hold full responsibility" "Yes, I am responsible." "But the design basically have flaws." "Flaws?" "As you know there are many kitchen stoves." "Ventilation is so insufficient." "Without proper ventilation." "The guest might complain." "The design was not taken into consideration at all." "If there's fire big problem with the sprinklers." "How is that?" "Specific problems have to rectify." "I don't think there is any water in those sprinkler." "No?" "General Manager" "Supervisor Lee!" "Prepare the party, Prepare the party" "I say go prepare the party now!" "Just wait till the party's over!" "Reporting" "Firefighter.." "Lee Sun-Woo 24th December transferred to Yeouido Fire Department." "That is all, Sir" "Can you do a good job?" "Yes" "I want to be an outstanding firefighter." "Hmm.. outstanding Firefighter" "What is outstanding fireman?" "Ha ha Hmm.. this it's not just the inspiration, it's the will." "Outstanding firefighter.." "Byung-Man" "Let's go." "Coming?" "Firefighters should always be ready for rescue action." "And then?" "Explain" "From what I seen here today." "You guys are not prepared at all." "Idling away is work also." "But.." "This is your place now.." "Hopefully you will get used to it." "Hey.." "Get unpack and take a shower." "I should get the equipment, Why take shower?" "How to say this.." "Say on wedding night." "If your lover didn't take a shower." "Leaned over you, what will you think?" "I think she is not ready." "Yes precisly.." "You should get ready right?" "Go take a shower." "Get fresh and inspire." "I get equipments." "Is Captain Kang Young-Ki on duty today?" "Why look for him?" "In our school, he was a legend." "Legend not heard of me?" "What is your name?" "Ah.. forget it." "Knowing me, will give you the headaches" "Oh.. hello" "Thanks" "Thank you for helping me." "Ah..don't mention.." "It's small matter." "Is that not mistletoe?" "What is that?" "You don't know mistletoe!" "Christmas time anyone under the mistletoe gets a kiss." "Huh!" "Ah..really?" "I don't know this!" ".." "I didn't sit..sit here intentionally for that!" "That I.." "I..." "Are you burnt?" "Ha ha..no It's tastier when the coffee is hot.." "Ha ha" "Are these marble?" "It' definitely not bricks. haha" "Church Elder Kim.." "This is like Paradise." "This is the Paradise" "Once you started working, you will know 90% of firefighters in the field knows nothing." "You listening to me?" "Yes ..yes listening." "Tell you this.." "Fire fighting, rescue and evacuation only a few are really good at these three." "Only person who are the expert with these. that's me." "Since you are following me." "You will soon become a real fireman." "What are you doing?" "We have got to go!" "I don't have any equipment yet." "Senior" "Senior" "Hello" "Senior" "Hurry up kid" "Senior" "Ha ha ha ha" "Congratulation" "Congratulation" "We welcome Lee Sun-Woo joining us" "Congratulate" "Stand attention" "Welcome to our team." "Woooh.." "Stand at attention." "Hands down." "Hands down." "Wow!" "Nice!" "Surprised?" "Uncle grow up!" "It's childish." "Where is dad?" "He is up to something." "Hana, you want to meet a woman who your father like?" "Father like?" "60th floor" "There is no water." "Where does the pipe connected to?" "Last year, It was retro-fitted to building's external right to the 80th floor." "Why like this?" "It's no big deal.." "What could possibly happen?" "You aware of the party tonight right?" "Be back home early ok..ya..?" "Sorry ma'am" "Kindly dispose the poo." "So what?" "House rule owners must clean up." "Ahh!" "Aunty.." "Why don't you clean it." "That is why they pay you right?" "Yes.." "Ok I will clean for you once." "But the next time you do it." "My Oh My..." "How dare you threaten me!" "Aunty.." "You!" "What's your name?" "Ms... sorry ma'am" "I am asking." "What's your name?" "Fun?" "Why is father so busy?" "Ah..as always" "Manager" "Manager" "I know the reason why." "The pipes are frozen from 60-80 floors there is no water" "Before the problem is fixed we have to add more fire extinguishers" "Supervisor Lee" "Can't you see everyone is busy?" "Sprinkler, extinguisher, no water." "Come on ..we have a party." "You don't know what is more important?" "Manager" "Manager" "Sorry.." "Director Jo" "Why the sudden cancelation of the Chopper flights?" "I was told, there will be high winds," "Strong turbulent wind." "Strong winds?" "How do we deal with this?" "Contact Disaster Prevention Department." "Yes" "Will call Disaster Prevention for Aviation." "Why Aviation Department?" "They control chopper flights." "Forget it." "Call Mayor of Seoul personally." "Understand." "Hana" "Daughter.." "Always like this." "Dad has to ensure the safety in this building." "Sorry.." "Just wait a little longer please." "Oh my.." "let me..move can't even make a child happy." "Hana dear" "Ah..you rascal.." "Why make her cry?" "Hana" "What happen?" "Hana what happen?" "Father.." "He" "Not accompanying me, wants to work." "What to do?" "We have to check the sprinkler for water." "Do you mind taking care of her?" "Miss Yun Hee is busy too." "We are busy." "Let's go." "Hana be good, listen to sister ok?" "Want to know why she cries?" "Hana will be an actress when she grows up." "What do you mean?" "I told her, if she wants Yun-Hee to play pretend to cry." "This kid is really good at crying." "With Yun Hee handed over to Hana." "Will surely succeed." "Hana the matchmaker," "Will matchmake the both of you.." "Great?" "Sister, Man of what Zodiac do you like?" "Gentle or Beastly type?" "What is your blood group?" "My dad is O" "Bachelor with a daughter possible?" "About this.." "A gentleman or O blood type is ok." "But have a child, I don't think so." "But" "If the child is as lovely as Hana." "Then it's acceptable." "This is for me?" "Our princess is

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of Iran's regime and they are growing politically powerful in their own right - the new president represents " the pasdaran party". They are not completely under Khameini's control and they - or at least factions within the Pasdaran - are spoiling for a fight with American and western interests. Other factions have been more pragmatic and provided America's IC with a good deal of useful intel on the Taliban and pre-war Iraq. Juan Cole dismisses the possibility of cooperation between al Qaida and the Pasdaran in Iraq or elsewhere. Generally Shiite-Sunni radicals would regard each other with great antipathy so as a rule of thumb that's fine but state and factional interests are also at work. I think that Cole, at best, has an unproven assumption since neither Iran's government nor al Qaida appear to be very homogenous. Their internal decision-making process is opaque and relationships are murky and often-times transient. Saddam talked to al Qaida, so does Iran, so did/does Pakistan, the Saudis and probably many, many others who are our allies. Iran has helped both secular and religious Sunni Arab terrorist groups in Palestine and the Iranian border is porous both in Azerbaijan-Kurdistan and in Baluchistan in the east. Who really knows what local Pasdaran authorities might be up to ? Or criminal gangs that might be cut-outs and smugglers for all comers with cash to pay ? Hard to know the players and their motivations without deep expertise which I do not have. Iran is run by bad people. Some of them are reckless idiots and some are cautious and pragmatic. Others are corrupt. That's what we have to work with and our best ace in the hole is that an Iraq engulfed in total civil war is on Iran's doorstep and not ours. So uncomfortably, there is some degree of common interest with Iran but not a lot.Abstract Systematic reviews constitute the highest quality of evidence and form the cornerstone of evidence-based medicine (EBM). Such reviews now inform everything from national health policy guidelines to bedside care. However, systematic reviews are extremely laborious to produce; researchers can no longer keep pace with the massive amount of evidence now being published. Semi-automation of systematic review production via machine learning (ML) has demonstrated the potential to substantially reduce reviewer workload while maintaining comprehensiveness. However, it is unlikely that machines will fully supplant human reviewers in the near future. Rather, human experts will probably remain in the loop, assisted by automated methods. Methods that exploit the intersection of human workers and ML models in the context of systematic reviews have not been explored at length. Furthermore, we believe there is substantial untapped potential in harnessing distributed crowd-workers to contribute to systematic reviews, and thus economize expert reviewer efforts. This novel avenue has largely been neglected as a means of increasing the efficiency of review production. We propose addressing this gap by developing and evaluating novel, hybrid approaches to generating systematic reviews that jointly incorporate domain experts (systematic reviewers), layperson workers recruited via crowdworking platforms such as Amazon's Mechanical Turk and volunteer citizen scientists, while simultaneously capitalizing on ML models. This innovative, hybrid approach will be the first in-depth exploration of intelligent ML/human systems that aim to reduce the workload in the production of biomedical systematic reviews. Our strong preliminary work demonstrates the promise of this general strategy.Balenciaga, fw17/18 The Fashion Alphabet today is about D, like Down Jacket. Brilliant ideas, especially in creative environment, can often originate from a real necessity, or even from an avoided tragedy. In this case we are in Alaska in 1935, during a fishing trip, with Eddie Bauer about to have hypothermia. He, after having risked his life, understands and decides that, for some freezing temperatures, wool wasn’t enough, opting for a lined jacket that’s light at the same time; so, thinking about Russian Army’s jacket, ha created a warm and waterproof piece of outerwear, padded with goose down, with diamond shaped seams in order to keep the padding fixed and tight tobthe body. Patented in 1940, it becomes popular in ’42, thanks to the B-9, the jacket for USA air force, able to keep warm with an outside temperature of -56°C. Then is the turn of Moncler, that in ’52 establishes the company, at first producing tents, sleeping bags and one model of hooded cloak: a cloack that during the years, transforms itself becoming the core business of the company and then an iconic and timeless garment. Paninari, in the 80s, elect the down jackets as their distinguishing feature, matched with Best Company sweatshirts and Timberland boots, wearing all types of them, made of shiny nylon, oversized, in bright colors. The down jacket, in those years, is no more perceived as a purely technical garment for mountaineering and skiing, but becomes a symbol, recognizable and categorizable, of a precise group in terms of identity and style. Anyone remembers the “cinepanettone” movies in the 90s, starring Jerry Calà, Ezio Greggio, Christian de Sica and Massimo Boldi wearing in the many “Vacanze di Natale” (Christmas Holidays) huge and colored down jackets, matched with bad taste, during their adventures/misadventures in the mountains. Today we can say that fashion has transformed the down jacket with so many shapes, weights, materials and colors, that we are far from those years, when we were children and we felt like the “Michelin Man”, clumsy and ugly, forced by our mothers to go out dressed that way because “it was cold”. From sport, to movies, to catwalks, the step was short, and the down jacket is now a fashionable garment, as important as a coat or a blazer in a man’s wardrobe, presented also by niche brands like Comme des Garçons, Rick Owens, Raf Simons and Balenciaga. With Balenciaga and with his brand Vetements, the new, young creative director, Demna Gvasalia, imposes through his fashion shows the use of the down jacket, in very bright- almost unmatchable- colors, bulky and unstructured, for fall/winter as well as spring/summer; due to his contribution also, for fashion victims, now than ever, the down jacket has become a must-have and the characterizing part of a cool and modern look. In the picture for The Men Issue by Federico Miletto, the down jacket (Fall/Winter 17/18 Moncler) made of black shiny nylon with maxi pockets, is matched with a cotton hooded tracksuit and a wool beanie, in the classic sport mood; as always, the streetstyle shot aside shows a way of wearing it which is casual, but urban and cool at the same time. In the following gallery, instead, there are several looks from f/w 17/18 fashion shows – with some previews from spring/summer 18 – of great designers, that present sleeveless, printed, short, long, hooded or not down jackets. Giovanni de Ruvo Alessandro Calascibetta has been active in fashion since the late 80s. He started off his career at L'Uomo Vogue, after that with Mondo Uomo. Afterward, he became Fashion Director at Harper's Bazaar Uomo, and in 2000 founded Uomo which he directed until 2003. Following that, he started collaborating with Rizzoli. Since january 2015 he is the Editor in Chief of Style Magazine, and still remains as Man Fashion Director for Io Donna and Sette.The death penalty arouses our passions as does few other issues. Some view taking another person’s life as just and reasonable punishment while others see it as an inhumane and barbaric act. But the intensity of feeling that capital punishment provokes often obscures its long and varied history in this country. Now, for the first time, we have a comprehensive history of the death penalty in the United States. Law professor Stuart Banner tells the story of how, over four centuries, dramatic changes have taken place in the ways capital punishment has been administered and experienced. In the seventeenth and eighteenth centuries, the penalty was standard for a laundry list of crimes—from adultery to murder, from arson to stealing horses. Hangings were public events, staged before audiences numbering in the thousands, attended by women and men, young and old, black and white alike. Early on, the gruesome spectacle had explicitly religious purposes—an event replete with sermons, confessions, and last-minute penitence—to promote the salvation of both the condemned and the crowd. Through the nineteenth century, the execution became desacralized, increasingly secular and private, in response to changing mores. In the twentieth and twenty-first centuries, ironically, as it has become a quiet, sanitary, technological procedure, the death penalty is as divisive as ever. By recreating what it was like to be the condemned, the executioner, and the spectator, Banner moves beyond the debates, to give us an unprecedented understanding of capital punishment’s many meanings. As nearly four thousand inmates are now on death row, and almost one hundred are currently being executed each year, the furious debate is unlikely to diminish. The Death Penalty is invaluable in understanding the American way of the ultimate punishment.Filtrate Shop Banray doesn’t know what you’re talking about. His name isn’t a cleverly disguised pun nor is his frame inspired by other sunglasses manufacturers. Banray’s his own man and that’s more than

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32.6). Indeed, Ligustinus and his comrades wanted to serve, but in their old posts as centurions. In 149 the consuls had no trouble calling up men for the Third Punic War because booty lured (Appian, Pun. 75.351) – a notable contrast with the resistance to levies for Spain just two years earlier (below). But sometimes the authorities had to compel enrolment. Warfare that brought mere toil and risk, without counterbalancing rewards, rarely appealed. Compulsion was required, for instance, in 193 for a campaign against Ligurian mountaineers, and in 169 as Ligustinus' no-longer-enticing war dragged on (Livy 34.56.1–2, 43.14.6–7). In such wars, serving soldiers sometimes – rightly – felt exploited and they complained. It happened in Spain in 206, when a corps mutinied outright for a time (Polybius 11.25–30; Livy 28.24–29), and there again in 180 under one of Ligustinus' commanders, Fulvius Flaccus (Livy 40.35.5–7, 36.4, 36.10–11). Spain was an unpopular theater: the wars were hard, dangerous and, after the first three decades of Roman rule exhausted the readily available loot, mostly unprofitable. The outbreak of yet another Celtiberian war in 151 deterred even prospective young officers from volunteering, until Africanus' grandson Scipio Aemilianus set the example (Polybius 35.4.2–14; Livy, Per. 48).2 2 The Impact of Military Service The economic and demographic impacts of these international wars are explored elsewhere. Here it is important to stress how constant a feature they were in Romans' and Italians' lives: a point well illustrated by Ligustinus' career. The regular demands for experienced recruits were one effect of another feature of Roman wars after 264: the unprecedented size of forces in service. Warfare had been a regular feature of Roman society from the outset, as Roman tradition itself recognized. The temple of Janus was closed, as a mark of total peace, supposedly only twice before Augustus' time – under King Numa (Livy 1.19.3) and in 235. But war-service from the third century on became more enduring and more large-scale. Third-century legions consisted, in principle, of 4,200 Roman infantry and 300 cavalry (the latter recruited from well-to-do citizens), plus Latin and Italian allied troops up to twice these numbers. In the First Punic War two consular armies, each two legions strong, were levied yearly. From 261 until 249, and then again in 242–241, further recruits were needed for the Romans' ventures on the sea, mainly drawn not from Roman citizens but from their maritime Italian allies. On a conservative calculation, the fleet sent to invade Africa in 256 was manned by 69,000 crewmen; the one raiding Africa in 253 had nearly as many, and in 249, when two consular fleets suffered disasters thanks to the enemy and the elements, their combined crews may have exceeded 80,000 men. The demands these efforts put on manpower were notable. When a big fleet and the legions both campaigned, as in 256 or 249, peninsular Italy had over a hundred thousand able-bodied men at war. On a rough estimate, in such years over 12 percent of available males were in arms. This was an unprecedented effort, although discontinuous and although its effects remain obscure.3 Even heavier demands ensued. There were some 155,000 men called up in 225 to face the Gallic invasion, and nearly as many (145,000 or so, for armies and fleets) at the start of Hannibal's war. At the height of this, in 212–211, with 25 legions in Italy, Cisalpine Gaul, Spain, and Sicily, and over 200 warships in commission, the total of Romans, Latins, and Italians under arms has been calculated at about 233,000. Even in the war's last year the republic's forces totaled around 110,000. These were extraordinary figures for a peninsula whose available manpower shortly before 218 totaled 770,000 according to Polybius (2.24); still extraordinary if, as has been argued, that figure should be corrected upwards to about 875,000 – very roughly, the military-age manpower of Iowa or East Anglia today. After 200, with commitments across the Mediterranean from Spain to Asia Minor, numbers soon went up again: over 212,000 in 190; in the last year of the Third Macedonian War, still about 150,000; and in 146, when Carthage and Corinth were sacked, the fleet and 12 legions (each now 5,500 strong and with allied contingents to match) totaled roughly the same again. Every decade between 225 and 146 (it has been reckoned) had at least 8 percent, and during the Second Punic War up to 29 percent, of Romans aged 16 and over in arms. In turn, though citizen-to-alliedratios varied during the same decades, the demands made on Latins and Italian socii will have been no lighter and often were heavier. Society was thus war-permeated on virtually a permanent basis. Most Romans and Italians must, like Ligustinus, have seen military service themselves or had kinsmen who did so, or both.4 3 Risk Levels in the Great Wars These great armaments had curiously contrasting fortunes in the third century and then the second. The first two Punic Wars were almost ruinously costly in lives. Fleets in the First Punic War were serious risks, thanks to nautical inexpertness and (occasionally) enemy skill. Polybius' naval figures, or some of them, have been suspected, but heavy ship-and crew-losses did occur, as mentioned above. Losses at sea hit the Italian socii especially hard, with the maritime allies providing most of the crews. In the Second Punic War, it was Roman armies which suffered catastrophes, not only in Italy but also in Cisalpine Gaul and Spain. Even if Roman losses at Cannae, for instance, are estimated downwards (not entirely convincingly) to 30,000 killed besides the 10,000 captured – and likewise Appian's claim (Pun. 134.635) that Hannibal destroyed 400 Italian cities and slew 300,000 enemies – yet the Italian peninsula and especially its southern half suffered badly from 15 years of warfare. Roman territory itself, outside Campania, was not heavily harmed after 217: yet the census of 203, carried out with particular care (Livy 29.37.5–6), returned only 214,000 citizens (though it did omit several thousand now-disfranchized Capuans and other Campanians). The impact on the loyal Italian populations must have been proportionately harsher, while those who had defected not only had to provide forces for Hannibal's war-effort but later suffered for this at the Romans' hands.5 The wars following were a revolutionary contrast. None in the East lasted more than four years. Roman casualties were far fewer: 700 killed, as against 8,000 Macedonians, at Cynoscephalae in 197, in which Sp. Ligustinus no doubt fought (Polybius 18.27.6; Livy 33.10.7); allegedly 324 at Magnesia in 190, where Antiochus III was crushed (Livy 37.44.2); and, Livy affirms, 100 – mostly Italian socii – at Pydna in 168, where 20,000 Macedonians died (44.42.7–8). Defeats could occur – a notable setback at Callicinus in 171 against the Macedonians, for instance (42.57–60) – but none was shattering. There were few naval actions and no major disasters. Even allowing for deaths from wounds, skirmishes, and ailments, Roman forces in eastern wars must have come to feel almost damage-proof as well as invincible. Although Spanish wars after 201 had fewer clear-cut endings – but instead much marching, many sieges, and opponents widely spread out and frustratingly resilient – Roman forces were smaller (usually a legion in either province), losses much lower, and a quarter-century, from 179 to 154, largely peaceful. Other second-century wars were small-scale, like the intermittent flare-ups in the Ligurian Mountains of northern Italy, in Sardinia and Corsica, and across the Adriatic in Illyria and Dalmatia; often enough, they were provoked by a general chasing booty, slaves, and gloria. 4 Why did Romans Fight? Men were expected to serve Mediterranean-wide, as Ligustinus' 22 campaigns illustrate. This was a feature that Senate and magistrates took for granted. They took for granted, too, that able-bodied men would serve, whether as volunteers or as conscripts. This enduring war-willingness of the ordinary citizen was one of the many strands that gave the Roman and Italian communities their extraordinarily tough texture, as Hannibal discovered and Polybius praises. Patriotic defense of a threatened patria gave Roman, and surely too Italian, soldiers a special esprit. Polybius stresses it in a contrast with the Carthaginians: [The Carthaginians] use foreign and mercenary forces, but the Romans

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850 papers at that time.) As Johnson observed in late 1942, "If _Dick Tracy_ were dropped from the _News_ , 300,000 readers would say, 'Oh dear!' But if Barnaby went from _PM_ , his 300 readers would write indignant letters." Though it never had a mass following, _Barnaby_ was by 1943 already earning Johnson five thousand dollars per year. Crockett Johnson, illustration from Constance Foster, _This Rich World: The Story of Money_ (New York: McBride, 1943). Reprinted with the permission of the Estate of Ruth Krauss, Stewart I. Edelstein, Executor. All Rights Reserved. In the spring of 1943, Johnson's career branched in another direction when he illustrated his first children's book, Constance J. Foster's _This Rich World: The Story of Money_. Along with Ruth Brindze's _Johnny Get Your Money's Worth_ (1938), _This Rich World_ is one of the first wave of children's books inspired by the consumer movement, designed to educate children about money and the marketplace. Expressing Foster's understanding that "many of our problems are economic at root," _This Rich World_ is also the sole children's book to display any hint that Johnson was once a _New Masses_ editor. One illustration notes that "Millionaire Cadwalader and thirty-dollar-a-week Tom Kent pay the same indirect taxes," a not-so-subtle criticism of the flat nature of the sales tax. Another suggests the precariousness of an economic system built on borrowing. One man in a suit gives a thousand-dollar deposit to another man in a suit, identified as banker. The banker then gives a thousand-dollar loan to another man in a suit, who gives a thousand-dollar check to the first man. For her part, Krauss soon became annoyed that when a student did research, the professor's name went on the publication. Moreover, her anthropological work made her acutely aware that children quickly absorb the values of their culture; effecting change would require reaching children early in life. When she discussed this idea with one of her friends, the friend responded, "You should be writing for children and not doing this." Inspired, Krauss started writing a book that she hoped would give children progressive ideas. She undertook an anthropological examination of prejudice that would teach children about the dangers of fascism and anti-Semitism. She took her manuscript to Harper and Brothers, riding the elevator up to the office of Ursula Nordstrom. Nearly a decade younger than Krauss, Nordstrom had joined Harper in 1931 and had become director of the Department of Books for Boys and Girls in 1940. When Krauss stepped off the elevator, she met Nordstrom's assistant, Charlotte Zolotow, who was supposed to screen visitors. Zolotow remembered a young woman with "disheveled hair," an "off-beat" sense of humor and "perspective about life," and obviously strong "feelings for children." After a few minutes, Zolotow went into Nordstrom's office and said, "You've got to see her, you've _got_ to see her!" Nordstrom and Krauss then talked for a long while. After Krauss left, Nordstrom told Zolotow, "She's wonderful, and she's going to write a book for us." But it would not be the manuscript Krauss had brought with her: "That was a life of Hitler, and I didn't think that would do for the children's book world." Before the end of World War II, children's books that tackle prejudice are rare. In the wake of the war, Ernest Crichlow's illustrations for Jerrold and Lorraine Beim's _Two Is a Team_ (1945) show black and white children who are best friends. H. A. and Margret Rey, the creators of _Curious George_ and acquaintances of Krauss and Johnson, created _Spotty_ (1945), in which spotted bunnies and white bunnies learn to get along. Ruth's manuscript was still a couple years ahead of the curve. Johnson, too, was working on what would become his first published book, revising and redrawing the best episodes of _Barnaby_ 's first ten months for publication in a single volume in the fall of 1943. He also continued to work on new daily _Barnaby_ strips, usually at night. Sitting at his desk and smoking a cigarette, Johnson would write and draw from 11:00 at night until 5:00 the next morning. He usually spent two nights writing the week's script, followed by two nights drawing the strips. Sometimes he was running so late that at 6:00 in the morning, he would bring his strips, ink still wet, to his neighbor Bob McNell, who would drop them off at the PM Syndicate on the way to his job in New York City. Like his character, Harold, Johnson relied on his ability to improvise under pressure. Just as, when falling off a cliff, Harold keeps "his wits and his purple crayon" and draws himself a balloon, so the approaching deadline focused Johnson's wit, igniting his imagination at night. ## 9 A GOOD MAN AND HIS GOOD WIFE Then, the man and the girl get married. They hold hands and they ride home —galoop galoop galoop galoop galoop galoop galoop galoop— together. —RUTH KRAUSS, _Somebody Else's Nut Tree and Other Tales from Children_ (1958) Dave's working methods meant that he and Ruth kept very different hours. Ruth rose at seven in the morning, after which she would take their two dogs for a walk along the Five Mile River. While he slept, Ruth began working on story ideas in her upstairs studio. Dave rose at noon, and Ruth fixed his breakfast and her lunch shortly thereafter. Then he would read for about two hours before working in their Victory Garden or going sailing while she swam. At 5:30, they had dinner, prepared by Ruth. Dave would start work on _Barnaby_ at 8:00 but found that he only really got under way after the 11:00 news. Despite living in different personal time zones, they were a very close couple—so close that, on 25 June 1943, they got married in New London, Connecticut. Harper gave Krauss a three-hundred-dollar advance and a contract for her first children's book in October 1943. Influenced by her work on Ruth Benedict's anthropological project on south Italian farming families, _A Good Man and His Good Wife_ offers a novel twist on folktales that mock a husband's failed attempts to copy his wife. In contrast, Krauss has mimicry supporting the husband's efforts to teach a lesson to the wife. Nonetheless, as Krauss admitted four years later, _A Good Man and His Good Wife_ "made some mistakes" because "the characters are cast in the conventional roles." The "good man" can never find anything because his good wife keeps moving things around, explaining, "My dear, I get so tired of the same things in the same place." Frustrated, he puts his shoe on his head, his garters around his neck, his tie around his knee, his pants on his arms, his coat on his legs, his spectacles on his elbow, and his socks on his ears. He then sits on the breakfast table, eating his napkin and wiping his face with a biscuit. When his wife exclaims, "My dear, this is ridiculous!," he replies, "My dear, I get so tired of the same things in the same place." The tactic cures "his good woman of a bad habit": she stops moving things around. Ad Reinhardt, two-page spread from Ruth Krauss, _A Good Man and His Good Wife_ (New York: Harper, 1944). Reproduced courtesy of Anna Reinhardt. Copyright © Anna Reinhardt. Ad Reinhardt received the same advance and worked up a rough dummy of the book while Krauss pondered her next project, an anti-ageist children's book, _I'm Tired of Being a Grandma_. Ursula Nordstrom found parts of the beginning amusing but considered the manuscript "forced" and "not a really good follow-up to _A Good Man and His Good Wife_." Krauss persisted, sending Nordstrom two new versions of the story because "our concepts of how people think, feel, and behave at certain ages, are socially conditioned," and these concepts were "practically as bad as race-prejudice, prejudice against women, immigrants, etc." Krauss pointed to "the Northwest Coast Indians of the United States and Canada" as holding "entirely different concepts about old people": "Among these Indians, the high point of romantic sex is old-age, about seventy to ninety. You're supposed to be romantic then; so, consequently, you are romantic then." Though sympathetic, Nordstrom did not think the idea worked as a story. Crockett Johnson with the cover drawing for _Barnaby_ (New York: Holt, 1943). Image courtesy of the Smithsonian Institution. Reprinted with the permission of the Estate of Ruth Krauss, Stewart I. Edelstein, Executor. All Rights Reserved. Also in October 1943, Henry Holt published _Barnaby_ , bringing the darling of the smart set to a wider audience. Rockwell Kent praised "Crockett Johnson's profound understanding of the psychology of the child, of grownups and of fairy godfathers." William Rose Benét, who won the 1942 Pulitzer

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work has been done yet on box-shape crystals. It is not obvious that long rods behave similarly to long ellipsoids. It was shown that the dipolar field in the middle of the end faces of a uniformly magnetized cylinder of Mn$_{12}$ Ac is opposite to the magnetization (the top of left column of page 4 of Ref. ). This should lead to spin flips at the ends of the cylinder with a subsequent proliferation into its body. The same can be expected for elongated boxes. Since the dipolar field in crystals of other than ellipsoidal shape is non-uniform, the MFA equations take the form of a large system of equations for all magnetic molecules considered separately. The model includes pseudospin variables $\sigma _{i}=\pm 1$ for molecules at each lattice site $i$ of a boby-centered tetragonal lattice. The magnetic moment of a molecule is $Sg\mu _{B}$ with $g=2.$ The dipolar field on magnetic molecule $i$ is the sum over positions of all other molecules $j$$$B_{i,z}^{(D)}=\frac{Sg\mu _{B}}{v_{0}}D_{i,zz},\qquad D_{i,zz}\equiv \sum_{j}\phi _{ij}\sigma _{jz}. \label{BviaD}$$ Here $D_{zz}$ is the reduced dipolar field and $$\phi _{ij}=v_{0}\frac{3\left( \mathbf{e}_{z}\cdot \mathbf{n}_{ij}\right) ^{2}-1}{r_{ij}^{3}},\qquad \mathbf{n}_{ij}\equiv \frac{\mathbf{r}_{ij}}{r_{ij}}. \label{psiijDef}$$ Inside a uniformly magnetized ellipsoid, $\sigma _{z}=\mathrm{const},$ the dipolar field is uniform and one has $D_{zz}=\bar{D}_{zz}\sigma _{z},$ where $$\bar{D}_{zz}=\bar{D}_{zz}^{(\mathrm{sph})}+4\pi \nu \left( 1/3-n^{(z)}\right) , \label{Dzzbar}$$ $\nu $ is the number of magnetic molecules per unit cell ($\nu =2$ for Mn$_{12}$ Ac) and $n^{(z)}=0,$ $1/3,$ and 1 for a cylinder, sphere, and disc, respectively. The reduced dipolar field in a sphere $\bar{D}_{zz}^{(\mathrm{sph})}$ depends on the lattice structure. For Mn$_{12}$ Ac direct lattice summation yields $\bar{D}_{zz}^{(\mathrm{sph})}=2.155$ that results in $\bar{D}_{zz}^{(\mathrm{cyl})}=10.53$ for a cylinder.[@garchu08prb] Then Eq. (\[BviaD\]) yields the dipolar field $B_{z}^{(D)}\simeq 52.6$ mT in an elongated sample that was also obtained experimentally.[@mchughetal09prb] The ground-state energy in the above uniform states is given by $$E_{0}=-(1/2)\bar{D}_{zz}E_{D},\qquad E_{D}\equiv \left( Sg\mu _{B}\right) ^{2}/v_{0}, \label{E0Def}$$ where $E_{D}$ is the dipolar energy, $E_{D}/k_{B}=0.0671$ K for Mn$_{12}$ Ac. The mean-field Curie temperature is given by[@garchu08prb] $$T_{C}=E_{D}\bar{D}_{zz}/k_{B} \label{TCsmallDelta}$$ that results in $T_{C}=0.707$ K. States with ferromagnetically ordered planes alternating in the $a$ or $b$ directions in *each* sublattice of Mn$_{12}$ Ac have $\bar{D}_{zz}=9.480,$ independently of the sample shape.[@garchu08prb] The state with alternating chains in each sublattice, directed along the $c$ direction has a very close value $\bar{D}_{zz}=9.475.$ For the two-sublattice antiferromagnetic ordering one obtains $\bar{D}_{zz}=8.102.$ Thus, in a strongly prolate ellipsoid of Mn$_{12}$ Ac ferromagnetic ordering is preferred. It is interesting to estimate how strongly prolate the ellipsoid has to be for this to be the case. Equating $\bar{D}_{zz}$ of Eq. (\[Dzzbar\]) to $\bar{D}_{zz}=9.480$ for the alternating-planes structure, one obtains the maximal demagnetizing factor $n^{(z)}=0.0419.$ Using the formula for prolate ellipsoids of revolution, one obtains that the minimal shape aspect ratio $R_{z}/R_{x}=6.13$ is required for ferromagnetic ordering. The longest crystal used in the experiments of Ref. has dimensions $0.4\times 0.4\times 2.4$ mm$^{3} $ and thus the aspect ratio 6 that would be still slightly insufficient for a crystal of ellipsoidal shape to order ferromagnetically. We will see below that even much longer box-shape Mn$_{12}$ Ac crystals *do not order ferromagnetically*. The reason for this is the above mentioned instability of the ferromagnetic ordering at the ends driven by the negative value of the dipolar field, $\bar{D}_{zz}=-2.03.$ [@garchu08prb] The system of Curie-Weiss equations for a crystal of molecular magnet in a uniform external field $B_{z}$ has the form $$\begin{aligned} \left\langle \sigma _{iz}\right\rangle &=&\tanh \frac{Sg\mu _{B}\left( B_{i,z}^{(D)}+B_{z}\right) }{k_{B}T} \notag \\ &=&\tanh \left( \frac{E_{D}/k_{B}}{T}\sum_{j}\phi _{ij}\left\langle \sigma _{jz}\right\rangle +\frac{h_{z}}{T}\right) , \label{CWEq}\end{aligned}$$ where $h_{z}\equiv Sg\mu _{B}B_{z}/k_{B}$. The linearized Curie-Weiss equations above $T_{c}$ can be cast into the matrix form $$\left( T\mathbb{I-V}\right) \cdot \left\langle \mathbf{\sigma }_{z}\right\rangle =h_{z}\mathbf{I.} \label{SusEqMatr}$$ Here $\mathbb{V}$ is the DDI matrix, $\left\{ \mathbb{V}\right\} _{ij}=\left( E_{D}/k_{B}\right) \phi _{ij},$ $\mathbb{I}$ is a unit matrix, $\left\{ \mathbb{I}\right\} _{ij}=\delta _{ij},$ and $\mathbf{I}$ is a unit vector, $\left\{ \mathbf{I}\right\} _{i}=1.$ In fact, position of a molecule in the lattice is defined by three numbers $i_{a},$ $i_{b},$ and $i_{c}$ corresponding to the three directions $a,$ $b,$ and $c,$ plus the sublattice index. The indices $i,j$ are compound indices running from 1 to the number of sites in the lattice $N.$ In terms of $i,j$ the matrix $\mathbb{V}$ is non-symmetric, so that care should be taken by distinguishing between its right and left eigenvectors. One can seek the solution in the form $\left\langle \mathbf{\sigma }_{z}\right\rangle =\sum_{\mu }C_{\mu }\mathbf{A}_{\mu }^{R},$ where $\mathbf{A}_{\mu }^{R}$ are right eigenvectors, $\mathbb{V}\cdot \mathbf{A}_{\mu }^{R}=T_{\mu }\mathbf{A}_{\mu }^{R},$ and $T_{\mu }$ are eigenvalues, $\mu =1,\ldots ,N.$ The right and left eigenvectors satisfy the orthonormality condition $\mathbf{A}_{\mu ^{\prime }}^{L}\cdot \mathbf{A}_{\mu }^{R}=\delta _{\mu ^{\prime }\mu },$ i.e., the matrix of left eigenvectors is the inverse of that of the right eigenvectors. Using the orthonormality, from Eq. (\[SusEqMatr\]) one obtains $C_{\mu }=\left( \mathbf{A}_{\mu }^{L}\cdot \mathbf{I}\right) h/\left( T-T_{\mu }\right) .$ For the susceptibility of the whole crystal $\chi =\left( 1/N\right) \left( \left\langle \mathbf{\sigma }_{z}\right\rangle \cdot \mathbf{I}\right) /h$ one finally obtains $$\chi =\frac{1}{N}\sum_{\mu =1}^{N}\frac{\left( \mathbf{A}_{\mu }^{L}\cdot \mathbf{I}\right) \left( \mathbf{A}_{\mu }^{R}\cdot \mathbf{I}\right) }{T-T_{\mu }}. \label{chiRes}$$ The ordering temperature $T_{C}$ can be identified with the maximal eigenvalue $T_{\mu },$ this is the first time as Eq. (\[chiRes\]) produces infinity as temperature is lowered. (11,5) Numerical calculations have been done using Wolfram Mathematica for box-shape crystals of

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RECORDING) FRIEDMAN: His view is that Israel should continue to build settlements. Certainly, nothing has been undertaken by the Palestinians to cause Israel to second-guess that view. ESTRIN: Here's what else Friedman has said. He's accused President Obama of blatant anti-Semitism after the White House took a tough stance against Democratic Senator Chuck Schumer who is Jewish and who opposed the Iranian nuclear deal. He's taken aim at the liberal pro-Israel group J Street, calling its American Jewish supporters far worse than kapos, Jewish concentration camp prisoners who helped the Nazis. Former Israeli Ambassador to the U.S. Zalman Shoval says he doesn't give much weight to Friedman's past statements. ZALMAN SHOVAL: The incoming administration has not yet made up its policy with regards to many things but certainly with regards to the Israeli-Palestinian conflict. Therefore, any statement made at this stage is really irrelevant. The ambassador will have to act with regards to the policy which President Trump will set. ESTRIN: An official with the Israeli Prime Minister's Office told NPR Benjamin Netanyahu is pleased with David Friedman's appointment and looks forward to working closely with him. Friedman says he looks forward to serving as ambassador from a new U.S. embassy in Jerusalem. And that's a whole other delicate matter - Israel and the Palestinians have competing claims to Jerusalem. No country has its embassy in the city to avoid taking sides in the dispute. Palestinian official Hanan Ashrawi says Friedman as ambassador presiding from a U.S. embassy in Jerusalem would be a provocation. HANAN ASHRAWI: The U.S. is on a direct collision course with the region and with the Arab and Islamic world as well as with people of good conscience all over the world. ESTRIN: David Friedman's appointment still needs Senate confirmation. Liberal Jewish groups say they'll fight it. J Street, the group whose supporters Friedman called Nazi kapos, is calling Friedman's nomination reckless. Daniel Estrin, NPR News, Jerusalem. Copyright © 2016 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information. NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced using a proprietary transcription process developed with NPR. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR’s programming is the audio record.Q: UWP key shortcut to run app I am currently swimming (drowning) into the MSDN, searching for an anwser for this problem : Like OneNote, I want my Universal Windows App to listen to a shortcut. Then run something, and display results. So I found this about Launching, resuming, and background tasks But I couldn't find something about listening to keyboards shortcuts. So I searched among classes, and found the BackgroundTaskBuilder Class. But it looks like the SetTrigger Method[1] doesn't register shortcuts. There's also this thing of Launching an app for results [2]. I can't realize how it can help me. I know how to listen to shortcuts when I am focusing the window of my program, BUT how can I do that when I am not ? I think it has to be a service running in background, and listening to that shortcut event. But I can't find that in the doc... I would appreciate some help and suggestions, thank you guys [1] : msdn.microsoft.com/fr-fr/library/windows/apps/xaml/windows.applicationmodel.background.backgroundtaskbuilder.aspx?cs-save-lang=1&cs-lang=javascript#code-snippet-1 [2]: msdn.microsoft.com/en-us/library/windows/apps/xaml/mt269386.aspx A: No way to do this with the current SDK. You can only manually add shortcut to your app to the desktop and taskbar and set it to be launched with a shortcut, like any other Windows app. MINNEAPOLIS On a recent April morning, Amy Klobuchar stood in her dining room flipping through a scrapbook of her father’s newspaper articles. She was on a brief break from the campaign trail, trading hard-hat tours of ethanol plants in Iowa and a uniform of nondescript blazers from New Hampshire town halls for a quiet morning at home in a comfy pastel fleece. Sen. Amy Klobuchar (D-Minn.) at her Minneapolis home in April. (Caroline Yang for The Washington Post) “I just remember being horrified by this headline,” she told me, pointing to a yellowing page that featured portraits of her, a recent high school graduate with hair down to her turtleneck, and her father, who wore long sideburns and a cardigan. The article detailed a bicycle trip the father-daughter duo had undertaken and was titled: Amy shows a 1981 news clipping from the bike trip she took with her journalist father from the Twin Cities to the Grand Tetons in Wyoming. (Caroline Yang for The Washington Post) “Jim Klobuchar and daughter encounter new relationship.” Amy, 58, shook her head and laughed, her short bob swaying side to side. It’s been something of a theme over the course of Amy’s life; both an evolving kinship with her father and being mortified by things he put in the paper. For decades, Jim Klobuchar was a daily columnist for the Minneapolis Star Tribune; part sportswriter, raconteur-adventurer, voice for the voiceless, and needler of the ruling class. Little in his life, or Amy’s, was off limits. Once, Jim had mentioned in a sports column that Amy had correctly diagnosed a football injury as being “groin”-related. That got her teased at school. There was the story Jim wrote about his divorce from Amy’s mother, Rose, the day after the split became official in 1976 (“My mom never liked that,” said Amy, whose mom died in 2010). And then, in 1993, there was the front-page article Jim had to write about his own arrest for drunken driving. Amy was a young lawyer by then, and at one of Jim’s hearings to determine his sentence, she took the stand. But she wasn’t there to defend him. “It was a prosecution,” Jim wrote later. Amy had plenty of material to work with. There was the time they drove to a bar after a Vikings game — he got tanked while she drank a 7-Up. The time he swerved his car into a ditch with her in the passenger seat. All the times he pretended the bottle he kept in his trunk was mouthwash, and the times Amy and her younger sister, Beth, sat in the room above the garage, staring out the window and waiting for him to come home. “I reminded him of the birthdays he missed,” Amy recalled now. She told him, “I don’t know if you remember,” but there was one in particular when he’d come home, smelling awful and without a present. Jim remembered. There are different ways to deal with a destructive personality. Beth, who struggled with her own addictions, dropped out of high school and, for a time, cut her father out of her life. His colleagues at the paper either didn’t notice his drinking, or pretended not to. Amy took a third option. At the hearing, she looked him in the eye and delivered a clear message. “I told him I loved him,” Amy said. “I would always love him. But he needed to get this help.” Amy; her sister, Beth; and her dad, Jim, in an undated family photo taken by her mother, Rose. (Family of Amy Klobuchar) It took a certain kind of toughness to confront her father in court, and 26 years later, Sen. Amy Klobuchar is pitching herself to America as a teller of hard truths. She has charted a path to the White House that goes through (not around) certain hard-luck swaths of Middle America now known as Trump Country but which used to be Democrat Country, and which still is Klobuchar Country. Places like the 8th Congressional District in Northern Minnesota, which saw one of the biggest swings in the country, from President Barack Obama to President Trump, but which continued to support Amy, as well. It was an inheritance, politically speaking. Jim Klobuchar was from those parts, forged in the Iron Range, a region of miners, hard drinkers and isolated communities tied together by union organizing. He built his career as a champion of the forgotten workers, the likes of whom he knew growing up. He remembered them in his writing, even as he forgot his daughter’s birthday. That wasn’t all Amy inherited from her father. Friends of Jim’s say they see a lot of him in Amy: the populist streak, the humor, and yes, the reports of a fierce temper. Intentionally or not, being the daughter of an alcoholic has become central to Amy’s presidential run. She brought him up during her star turn at a Brett M. Kavanaugh Supreme Court confirmation hearing, where she interrogated the beer-loving judge while appearing deeply unimpressed with his anger and self-pity. And last

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a great place for kids to learn about sea mammals. It also provides information about volunteering and reporting sightings of whales and dolphins. #### Sea Life Surveys ( 01688-302916; www.sealifesurveys.com) Sea Life Surveys, based in the new harbour building beside the main car park, runs whale-watching boat trips out of Tobermory harbour. ## THAR SHE BLOWS! The North Atlantic Drift – a swirling tendril of the Gulf Stream – carries warm water into the cold, nutrient-rich seas off the Scottish coast, resulting in huge blooms of plankton. Small fish feed on the plankton, and bigger fish feed on the smaller fish... This huge seafood smorgasbord attracts large numbers of marine mammals, from harbour porpoises and dolphins to minke whales and even – though sightings are rare – humpback and sperm whales. In contrast to Iceland and Norway, Scotland has cashed in on the abundance of minke whales off its coast by embracing whale watching rather than whaling. There are now dozens of operators around the coast offering whale-watching boat trips lasting from a couple of hours to all day; some have whale-sighting success rates of 95% in summer. While seals, porpoises and dolphins can be seen year-round, minke whales are migratory. The best time to see them is from June to August, with August being the peak month for sightings. The website of the **Hebridean Whale & Dolphin Trust** (www.whaledolphintrust.co.uk) has lots of information on the species you are likely to see, and how to identify them. A booklet titled _Is It a Whale?_ is available from tourist offices and bookshops, and provides tips on identifying the various species of marine mammal that you're likely to see. ### Inveraray #### Inveraray Castle (www.inveraray-castle.com; adult/child £9/6.10; 10am-5.45pm Apr-Oct) Inveraray Castle has been the seat of the dukes of Argyll – chiefs of Clan Campbell – since the 15th century. The 18th-century building, with its fairy-tale turrets and fake battlements, houses an impressive armoury hall, its walls patterned with a collection of more than 1000 pole arms, dirks, muskets and Lochaber axes. The castle is 500m north of town, entered from the A819 Dalmally road. #### Inveraray Jail (www.inverarayjail.co.uk; Church Sq; adult/child £8.25/5.50; 9.30am-6pm Apr-Oct, 10am-5pm Nov-Mar) Inveraray Jail is an award-winning, interactive tourist attraction where you can sit in on a trial, try out a cell and discover the harsh torture meted out to unfortunate prisoners. The attention to detail – including a life-sized model of an inmate squatting on a 19th-century toilet – more than makes up for the sometimes tedious commentary. ### Loch Lomond The 'bonnie banks' and 'bonnie braes' of Loch Lomond have long been Glasgow's rural retreat – a scenic region of hills, lochs and healthy fresh air within easy reach of Scotland's largest city. The main tourist focus is along the A82 on the loch's western shore, and at the southern end, around Balloch, which can occasionally be a nightmare of jet skis and motorboats. The eastern shore is a little quieter. The region's importance was recognised when it became the heart of **Loch Lomond & the Trossachs National Park** (www.lochlomond-trossachs.org) – Scotland's first national park, created in 2002. #### Activities #### Boat Trips The main centre for boat trips is Balloch, where **Sweeney's Cruises** (www.sweeney.uk.com; Balloch Rd) offers a range of trips including a one-hour cruise to Inchmurrin and back (adult/child £7/4, departs hourly). #### Cruise Loch Lomond (www.cruiselochlomondltd.com) Based in Tarbet, offering trips to Inversnaid and Rob Roy MacGregor's Cave. You can also be dropped off at Rowardennan and picked up at Inversnaid after a 9-mile hike along the West Highland Way. #### Lomond Adventure ( 01360-870218) Based in Balmaha, this outfit rents out Canadian canoes (£30 per day) and sea kayaks (£25). ### Loch Ness Deep, dark and narrow, Loch Ness stretches for 23 miles between Inverness and Fort Augustus. Its bitterly cold waters have been extensively explored in search of Nessie, the elusive Loch Ness monster, but most visitors see her only in cardboard-cutout form at the monster exhibitions. The busy A82 road runs along the northwestern shore, while the more tranquil and picturesque B862 follows the southeastern shore. #### DRUMNADROCHIT Seized by monster madness, Drumnadrochit is a hotbed of beastie fever, with two monster exhibitions battling it out for the tourist dollar. #### Loch Ness Exhibition Centre (www.loch-ness-scotland.com; adult/child £6.50/4.50; 9am-6.30pm Jul & Aug, to 6pm Jun & Sep, 9.30am-5pm Feb-May & Oct, 10am-3.30pm Nov-Jan) The Loch Ness Exhibition Centre is the better of the two Nessie-themed attractions, with a scientific approach that allows you to weigh the evidence for yourself. #### Nessie Hunter ( 01456-450395; www.lochness-cruises.com) One-hour monster-hunting cruises (adult/child £10/8), complete with sonar and underwater cameras, are available aboard the Nessie Hunter. Cruises depart hourly from Drumnadrochit, 9am to 6pm daily from Easter to December. #### URQUHART CASTLE Commanding a brilliant location with outstanding views (on a clear day), **Urquhart Castle** (HS; adult/child £7/4.20; 9.30am-6pm Apr-Sep, to 5pm Oct, to 4.30pm Nov-Mar) is a popular Nessie-watching hot spot. A huge visitor centre (most of which is beneath ground level) includes a video theatre (with a dramatic 'unveiling' of the castle at the end of the film), displays of medieval items discovered in the castle, a huge gift shop and a restaurant. The site is often very crowded in summer. ## STRANGE SPECTACLE ON LOCH NESS Highland folklore is filled with tales of strange creatures living in lochs and rivers, notably the kelpie (water horse) that lures unwary travellers to their doom. The use of the term 'monster', however, is a relatively recent phenomenon whose origins lie in an article published in the _Inverness Courier_ on 2 May 1933, entitled 'Strange Spectacle on Loch Ness'. The article recounted the sighting of a disturbance in the loch by Mrs Aldie Mackay and her husband: 'There the creature disported itself, rolling and plunging for fully a minute, its body resembling that of a whale, and the water cascading and churning like a simmering cauldron.' The London newspapers couldn't resist. In December 1933 the _Daily Mail_ sent Marmaduke Wetherall, a film director and big-game hunter, to Loch Ness to track down the beast. Within days he found 'reptilian' footprints in the shoreline mud (soon revealed to have been made with a stuffed hippopotamus foot, possibly an umbrella stand). Then in April 1934 came the famous 'long-necked monster' photograph taken by the seemingly reputable Harley St surgeon Colonel Kenneth Wilson. The press went mad and the rest, as they say, is history. In 1994, however, Christian Spurling – Wetherall's stepson, by then 90 years old – revealed that the most famous photo of Nessie ever taken was in fact a hoax, perpetrated by his stepfather with Wilson's help. Today, of course, there are those who claim that Spurling's confession is itself a hoax. And, ironically, the researcher who exposed the surgeon's photo as a fake still believes wholeheartedly in the monster's existence. Hoax or not, there's no denying that the bizarre mini-industry that has grown up around Loch Ness and its mysterious monster since that eventful summer 75 years ago is the strangest spectacle of all. ### Orkney Islands #### MAES HOWE Egypt has the pyramids, Scotland has **Maes Howe** (HS; 01856-761606; www

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6803, 273, 11488, 1307, 19133, 347, 2529, 4321, 15, 187, 187, 9340, 1712, 4538, 1047, 94, 187, 6877, 187, 187, 23062, 14, 12792, 22649, 247, 1846, 3320, 11118, 273, 32647, 14520, 1712, 4538, 1010, 94, 187, 2518, 7040, 187, 187, 2214, 776, 8900, 11419, 14, 12792, 273, 41346, 6578, 13, 359, 5728, 27913, 941, 5239, 4508, 884, 3907, 3110, 27361, 326, 1801, 4206, 1966, 1501, 14, 44307, 27102, 7944, 275, 27360, 3530, 313, 8970, 2219, 13, 13620, 5760, 10, 313, 3235, 544, 18, 1084, 10297, 18, 910, 709, 14, 881, 568, 2420, 4982, 14117, 1873, 544, 18, 1084, 13270, 18, 910, 709, 14, 881, 568, 8236, 28479, 5270, 322, 18, 10, 1254, 1311, 1423, 1184, 14, 8088, 1311, 1717, 1656, 2053, 3530, 497, 2797, 432, 2710, 17902, 4811, 13, 26382, 13, 15919, 49237, 13, 285, 14472, 12045, 275, 1740, 41346, 6578, 313, 2350, 13, 6442, 13, 10116, 13, 285, 38410, 481, 2053, 4679, 908, 5093, 1027, 3320, 2048, 27913, 13498, 15, 1284, 690, 941, 5239, 513, 417, 2085, 9305, 941, 285, 8654, 27913, 638, 14, 21678, 5609, 9184, 2439, 13498, 13, 359, 20582, 11742, 2625, 26112, 13, 285, 10141, 326, 512, 941, 497, 2412, 19, 13657, 285, 2677, 587, 12650, 2439, 512, 3530, 275, 253, 2173, 3368, 15, 1310, 417, 13, 359, 2412, 19, 13657, 285, 2677, 587, 12650, 253, 941, 15, 844, 908, 2728, 21903, 347, 2931, 275, 253, 3236, 16516, 323, 2728, 7147, 1453, 4408, 14023, 15, 380, 2908, 2175, 671, 3839, 2692, 271, 3434, 281, 2363, 14, 8992, 2219, 285, 5760, 15, 187, 187, 1992, 4271, 253, 954, 10237, 285, 12724, 21673, 4469, 3608, 2439, 41346, 6578, 13, 359, 908, 247, 3320, 2048, 11419, 14, 12792, 2746, 1254, 1311, 938, 1656, 25487, 13, 436, 2746, 24772, 253, 1055, 9552, 13, 5118, 347, 388, 40967, 8, 10904, 475, 72, 2992, 323, 1016, 3320, 432, 1016, 941, 873, 281, 6642, 247, 19817, 1599, 3064, 275, 3320, 2048, 313, 2887, 20898, 285, 13277, 323, 4278, 481, 1198, 247, 3320, 281, 320, 2783, 21673, 4469, 275, 253, 11419, 14, 12792, 13, 359, 2424, 352, 281, 320, 4080, 275, 512, 884, 3110, 27361, 285, 323, 697, 1055, 1979, 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346, 35789, 14, 531, 14, 69, 42294, 14, 483, 3, 1783, 497, 2783, 281, 1957, 253, 1846, 3608, 7915, 10088, 2439, 41346, 6578, 15, 844, 3636, 31619, 824, 12724, 21673, 4469, 3608, 313, 2222, 598, 14, 10088, 13, 26472, 1066, 14, 10088, 10, 30472, 273, 534, 8578, 273, 41346, 6578, 497, 5867, 313, 14087, 1873, 544, 18, 1084, 13270, 18, 910, 709, 14, 881, 568, 8236, 28479, 5270, 322, 20, 481, 733, 310, 1896, 326, 627, 778, 1335, 320, 1534, 19331, 275, 253, 1055, 9552, 273, 841, 3608, 875, 1027, 41346, 6578, 28, 2299, 13, 436, 19331, 778, 5224, 326, 253, 1072, 7178, 310, 4469, 387, 1027, 2308, 875, 41346, 6578, 13, 533, 275, 253, 1072, 3884, 15, 3813, 13, 359, 858, 417, 2007, 1908, 436, 19331, 323, 253, 31619, 3608, 15, 187, 187, 9301, 13, 359, 17618, 841, 3608, 275, 1264, 3081, 3110, 27361, 273, 41346, 2728, 11253, 273, 898, 2227, 3530, 313, 31730, 2219, 13, 36153, 5760, 10, 313, 3235, 544, 18, 1084, 10297, 18, 910, 709, 14, 881, 568, 2420, 4982, 14117, 1873, 544, 18, 1084, 13270, 18, 910, 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Prefrontal Cortex\[[@CR46]\]148^a^20 to 78 years**TOTAL221**^a^data set restricted to individuals \> 20 years old, lowering the sample size to 148. We used the Database for Annotation, Visualization and Integrated Discovery (DAVID) \[[@CR48]\] tool to assess the enrichment for GO terms in the aging correlated and non-correlated components of the CNM. Assessment of cell type specificity in differentially expressed genes {#Sec10} --------------------------------------------------------------------- To evaluate whether the CNM may reflect changes in cell-type composition, we assessed the overlap between our module and genes enriched in isolated neurons, astrocytes, oligodendrocytes \[[@CR49]\],\[[@CR50]\], microglia or peripheral macrophages \[[@CR51]\],\[[@CR52]\] from normal mice, as well as genes enriched in astrocytes isolated from mice following stroke or LPS treatment \[[@CR53]\]. While these data sets were derived from multiple experiments and could not be compared directly, they all used the same platform, the Affymetrix Mouse Genome 430 2.0 Array. This permitted us to use the Gene Expression Commons (GEXC) tool \[[@CR52]\] to evaluate gene expression activity in these cell type specific data sets relative to 11,939 public gene array data sets, which allows for the classification of genes as "active" or "inactive". We used the "Expression Pattern Search" function in GEXC to identify genes from the CNM that were "active" in the cell type of interest and "inactive" in all others. We then performed manual visualization of differential gene expression in GEXC to confirm and finalize the assigned cell-type enrichment category for each gene in the CNM. For genes only modestly differentially expressed between neurons, oligodendrocytes and astrocytes, we deferred to the directly compared cell type-specific gene lists from \[[@CR49]\]. Genes not enriched in a single given cell type based on these criteria were regarded as not being cell-type specific. Assessment of enrichment for microglia polarization states and gliosis {#Sec11} ---------------------------------------------------------------------- We created custom gene sets from published gene lists generated from transcriptome analyses of human M1 and M2-polarized macrophages \[[@CR54]\], microglia from the end stage of a mouse model of ALS \[[@CR55]\], and astrocytes from mice 24 hours following treatment with lipopolysaccharide (LPS) or middle cerebral artery occlusion (MCAO) \[[@CR53]\]. For the mouse data, we downloaded the gene lists and converted mouse gene symbols to human HUGO gene symbols prior to inputting the custom gene sets into GSEA \[[@CR41]\]. We used the GSEA PreRank option to assess the enrichment for these custom gene sets in the complete list of discovery meta-analysis genes with their corresponding meta-effect sizes, regardless of significance. Identification of enriched transcription factors using ENCODE data {#Sec12} ------------------------------------------------------------------ We used the ENCODE ChIP-Seq Significance Tool \[[@CR56]\] to identify transcription factors enriched in the up-regulated and down-regulated components of the CNM. We used the following parameters: organism, human (hg19); regulatory element type, protein-coding genes; ID type, symbol; background regions, a list of all genes assessed across all 10 discovery data sets; analysis window center, TSS/5' end (transcription start site); upstream and downstream window size relative to TSS, 500 bp; and cell lines, all. We repeated this analysis for genes positively and negatively correlated with aging and for published gene lists where indicated. Identification of unique disease-specific patterns of gene expression changes {#Sec13} ----------------------------------------------------------------------------- To identify patterns in gene expression changes that are unique to each of the neurodegenerative diseases evaluated, for each specific disease, we repeated the aforementioned gene expression meta-analysis on the disease by itself, as well as separately on the other three diseases together. We then removed genes from the individual disease meta-analysis output gene list that were significantly differentially expressed from the three-disease meta-analysis (FDR ≤ 0.05), thereby omitting common differentially expressed genes in neurodegeneration from disease-specific gene lists. We restricted the gene lists to genes that were measured in all 10 data sets. The resulting individual disease meta-analysis gene list was then input into GSEA PreRank for assessment of GO term enrichment as described earlier. Results {#Sec14} ======= Meta-analysis identifies a common gene signature of neurodegeneration {#Sec15} --------------------------------------------------------------------- For our discovery meta-analysis of neurodegenerative diseases, we collected microarray data sets containing 10 independent patient cohorts that profiled human post-mortem CNS tissues in 285 samples (150 cases, 135 controls) (Table [1](#Tab1){ref-type="table"}, Additional file [1](#MOESM1){ref-type="media"}: Table S1) \[[@CR22]\]-\[[@CR29]\]. These samples were obtained from various cortical regions, hippocampus, basal ganglia, and spinal cord in four neurodegenerative diseases (AD, PD, HD, and ALS). These experiments used seven different gene expression microarray platforms. As some data sets do not provide raw data and optimal microarray pre-processing techniques differ across platforms, we downloaded processed signal intensities, and checked that all data were log2 transformed and quantile normalized across all samples in the specific experiment. If not, we log2 transformed and quantile normalized the data. We used disease phenotypes as defined in the original publications for disease versus control tissue comparisons. The included studies also generally showed an effort to age-match cases and controls. To identify the most robust and consistently differentially expressed genes across neurodegenerative diseases, we used a gene expression meta-analysis approach \[[@CR20]\]. Briefly, this approach combines the effect sizes, calculated as Hedges' adjusted *g*, for each gene from each data set to estimate a standardized mean difference in gene expression (see Materials and Methods for details). For a gene to be considered differentially expressed in the meta-analysis, we required it to be measured in all 10 patient cohorts and for its effect size to have a significant false discovery rate (FDR ≤ 5%). This analysis yielded lists of 3,078 and 3,565 significantly up-regulated and down-regulated genes, respectively (Additional file [1](#MOESM1){ref-type="media"}: Table S2). However, because of the heterogeneity in effect sizes, it is possible that some of the genes may be differentially expressed in one or more neurodegenerative diseases, but not all. Because our goal is to identify a set of common genes that are differentially expressed in the same direction across all neurodegenerative diseases, we carried out "leave-one-disease-out" analysis. In this analysis, we repeated the meta-analysis four additional times, each time removing patient cohorts corresponding to one disease prior to analysis of the remaining patient cohorts for the other three diseases. Genes that remained significantly differentially expressed (FDR ≤ 5%) in all four iterations of the "leave-one-disease-out" analysis were considered to represent the common genes dysregulated across neurodegenerative diseases. We identified 322 such consistently differentially expressed genes (95 up-regulated, 227 down-regulated) irrespective of which subset of neurodegenerative diseases were analyzed (Additional file [1](#MOESM1){ref-type="media"}: Table S3). It is possible that there may still be significant heterogeneity in the effect sizes of these genes between different neurodegenerative diseases; however, this heterogeneity may indicate that the same pathway is expressed at different levels between neurodegenerative diseases, but in the same direction. Therefore, we did not further consider this heterogeneity for the 322 genes. Next, we validated these genes in three additional patient cohorts of neurodegenerative disease consisting of 985 samples (643 cases, 342 controls) (Table [1](#Tab1){ref-type="table"}, Additional file [1](#MOESM1){ref-type="media"}: Table S1) \[[@CR30]\],\[[@CR38]\]. These data sets profiled human post-mortem CNS tissue samples from patients with AD or HD. Large validation data sets were not publicly available for PD and ALS. We found 73/95 (76.8%) up-regulated genes and 170/227 (74.9%) down-regulated genes (total of 243 genes) were also significantly differentially expressed in the validation cohorts (Figure [2](#Fig2){ref-type="fig"} and Additional file [2](#MOESM2){ref-type="media"}: Figure S1). Henceforth, these 243 validated genes are referred to as a *common neurodegeneration module* (CNM) (Table [3](#Tab3){ref-type="table"} and Additional file [1](#MOESM1){ref-type="media"}: Table S4).Figure 2**Meta-analysis and leave-one-disease-out analysis reveal common differentially expressed genes across neurodegenerative diseases.** Heat map shows consistent differential expression in the discovery, validation, and secondary validation data sets. Columns denote CNM genes ranked from highest to lowest standardized mean difference (Hedges' *g* in log2 scale), from left to right. Rows denote data sets used in each stage of meta-analysis. Heat map colors indicate Hedges' *g* in log2 scale. Refer to Table [1](#Tab1){ref-type="table"} for data set information. ALS, amyotrophic lateral sclerosis; HD, Huntington's disease; PD, Parkinson's disease; AD, Alzheimer's disease; PiD, classical Pick's disease; FTLD, frontotemporal lobar dementia (Constantinidis type C); PSP, progressive supranuclear palsy; FTLD-GRNpos, frontotemporal lobar dementia with ubiquitin- and TDP-43-positive inclusions, progranulin mutation positive; FTLD-GRNneg, frontotemporal lobar dementia with ubiquitin- and TDP-43-positive inclusions, progranulin mutation negative. ######

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? This man, Mrs. Kennedy, has saved my life and honour more than once, and it is no humiliation for me to go on my knees before him." Perhaps there was something in her face and the tone of her voice that touched the Englishwoman's heart, in spite of her outraged sense of propriety. The stern expression disappeared from her features, and she said with friendly, almost motherly gentleness-- "Come, my poor child! I have certainly no right to set up for a judge of your actions. But I am certainly old enough for you to trust in me." Edith, overcome by this sudden kindness, leaned her head on Mrs. Kennedy's shoulder. Heideck felt it would be best to leave the two ladies to themselves. "If you will permit me, ladies, I will leave you for the present." With a rapid movement Edith laid her hand upon his arm. "You give me your word, Captain Heideck, that you will not leave without saying good-bye to me?" "I give you my word." He left the room in a most painful state of mind. It seemed as if, in the fulfilment of his duty, he would have to pass over the body of the being who was dearest to him on earth. In the evening Mrs. Kennedy's maid brought him a short note from Edith, asking him to come to her at once. He found her in her dimly-lighted room on the couch; but as he entered she got up and went to meet him with apparent calmness. "You are right, my friend; I have in the meantime come to my senses again. Nothing else is possible--we must part." "I swear to you, Edith--" "Swear nothing. The future is in God's hands alone." She drew from the ring-finger of her left hand the hoop-ring, set in valuable brilliants, which had given rise to their first serious conversation. "Take this ring, my friend, and think of me whenever you look at it." Tears choked her utterance. "Have no anxiety for me and my future. I am going with the Kennedys to England." XXV A SUSPICIOUS FISHING-SMACK A raw north wind swept over the island of Walcheren and the mouth of the West Schelde, ruffling into tiny waves the water of the broad stream, which in the twilight looked like a shoreless sea. Only those acquainted with the ground knew that the flashing lights of the beacons at Flushing on the right and at Fort Frederik Hendrik on the left marked the limits of the wide mouth of the harbour. Here, in 1809, when Holland was under the rule of Napoleon Bonaparte, a powerful English fleet had entered the Schelde to attack Flushing, and take the fortress. In the centre, between the two lights, which were about three miles apart, the German cruiser Gefion lay tossing at anchor. On the deck stood Heideck, who on his return had been promoted to major and appointed to the intelligence department for the coast district of Holland. In the afternoon he had seen a vessel entering the Schelde, which the pilot had identified as one of the fishing-smacks plying between the Shetland Islands and the Dutch ports. Heideck had informed the captain of the Gefion of his suspicion that the smack might be intended for another purpose than trading in herrings. The little vessel had put in on the left bank, between the villages of Breskens and Kadzand, and Heideck decided to row across to it. Six marines and four sailors, under the command of a mate, manned one of the Gefion's boats, and set out for the left bank in the direction of the suspected vessel. It cost the oarsmen, struggling with the tide and wind which came howling from the sea, nearly half an hour's hard work before they saw the dark hull of the smack emerging clearly outlined before them. A hoarse voice from on board asked what they wanted. "His Majesty's service!" answered Heideck, and, as the boat lay to, he threw off his cloak, so as to spring on deck more easily. Three men, in the dark, woollen smock and tarpaulined hat of coast fishermen, approached him and, in answer to his inquiry for the master, told him, in an unintelligible mixture of Dutch and German, that he had gone ashore. "His name?" "Maaning Brandelaar." "What is the name of this vessel?" "Bressay." The answers were given with hesitation and sullenly, and the three men showed such evident signs of irritation that Heideck felt they would have gladly thrown him overboard had it not been for the respect inspired by his uniform. "Where from?" he asked. "From Lerwick." "Where to?" "We are going to sell our herrings. We are respectable people, Herr major." "Where are you going to sell your herrings?" "Where we can. The skipper has gone to Breskens. He intended to be back soon." Heideck looked round. The smack had put to in a little bay, where the water was quiet. The village of Breskens and the little watering-place, Kadzand, were both so near that the lighted windows could be seen. It was nine o'clock--rather late for the business which Maaning Brandelaar intended to transact at Breskens. Heideck sent the marines on deck with orders to see that no one left the ship before the captain returned. He then ordered a lantern to be lighted to examine below. It was a long time before the lantern was ready, and it burned so dully that Heideck preferred to use the electric lamp which he always carried with him as well as his revolver. He climbed down the stairs into the hold and found that the smell of pickled herrings, which he had noticed on deck, was sufficiently explained by the cargo. In the little cabin two men were sitting, drinking grog and smoking short clay pipes. Heideck greeted them courteously and took a seat near them. They spoke English with a broad Scotch accent, and used many peculiar expressions which Heideck did not understand. They declared they were natives of the island of Bressay. Heideck gathered from their conversation that the smack belonged to a shipowner of Rotterdam, whose name they appeared not to know or could not pronounce. They were very guarded and reserved in their statements generally. Heideck waited half an hour, an hour--but still no signs of the captain. He began to feel hungry, and throwing a piece of money on the table, asked whether they could give him anything to eat. The fishermen opened the cupboard in the wall of the cabin and brought out a large piece of ham, half a loaf of black bread, and a knife and fork. Heideck noticed two small white loaves in the cupboard amongst some glasses and bottles. "Give me some white bread," said he. The man who had brought out the eatables murmured something unintelligible to Heideck and shut the cupboard again without complying with his request. His behaviour could not help striking Heideck as curious. He had, as a matter of fact, only asked for white bread because the black was old, dry, and uncommonly coarse; but now the suspicion forced itself upon him that there was some special meaning behind the rude and contemptuous manner in which his request had been received. "You don't seem to have understood me," he said. "I should like the white bread." "It belongs to the captain," was the reply; "we mustn't take it." "I will pay for it. Your captain will certainly have no objection." The men pretended not to hear. Heideck repeated his request in a stern and commanding tone. The men looked at each other; then one of them went to the cupboard, took out the white bread, and set it on the table. Heideck cut it and found it very good. He ate heartily of it, wondering at the same time why the men had been so disobliging about it at first. When he took up the bread again to cut himself off a second piece, it occurred to him that it was remarkably heavy. He cut into the middle and, finding that the blade of the knife struck on something hard, he broke the loaf in two. The glitter of gold met his eyes. He investigated further and drew out, one after the other, thirty golden coins with the head of the Queen of England upon them. Thirty pounds sterling had been concealed in the loaf. "Very nourishing bread of yours," said he, looking keenly at the men,

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rose up off my leg? That it let your other brother pet him? Or could it—?” Carla told Wynter to behave. “Yes, ma’am, but you have to realize that I’m in over my head here. I’m a good person. Or I try to be. Why is all this crap going on?” “I would imagine that it has a great deal to do with what you are.” He looked at the dragons. “They’re a matched pair. And from what I’ve been told from my brothers, when yours was on your leg, it looked just like the one on my back. We, I guess you could say, were meant to be together.” “That is right, my lord. Since the beginning of the end of dragons, you were meant to be with a female that would be your match and mate in all things.” The female dragon laid her head down on the floor and the male joined her. “We have been waiting for generations for you, Wynter Snow. I think we were ready to give up hope that you’d ever be born.” “Great, I was born to be a screw up.” Tristan laughed. “What do you find so funny? If they’re right, and at the moment I can’t see anything wrong with their logic, then we’re together. But I’m going to be spending the rest of my life behind bars, if they don’t put me to death instead.” “There will be no sentencing for any of those. I’ve spoken to my brother, and he said that you’re going to be exonerated for the mall incident, as well as what happened at the hospital.” She asked him what had gone on there. “You disappeared.” “Oh, yes, well, your brother freaked us all out with the dragon. Did they tell you that he rose up from my flesh so that he could pet him? What sort of fucked up shit is that?” She looked at her mom. “I’m sorry, Mom, but you have to agree—it’s messed up.” “I do agree. But what happens now? I mean, other than that the dragon is no longer a part of her.” The male dragon stood up. “Do you know what happens now? I don’t even know what to call you.” “We have no names as yet, my lady. We are just male and female dragon.” Wynter asked if they were to name them. “If you wish to name us that would be fine. But it does not matter to us. We both belong to the two of you. We are mates as well.” “Does this mean that I can’t shift into my dragon anymore?” That had only just occurred to him. And it would piss him off if he weren’t able to fly anymore. Male told him that he could. So could the young miss. “She’s able to be a dragon?” “Wait, wait, and wait. I don’t want to be a dragon. No offense to you guys, but I’m happy being the plain old human that I am.” Tristan told her that she wasn’t human, never had been. “Oh, but you’re wrong about that. I’m a human, damn it, and you’d better not be fucking around with me to make me anything else.” “You’re immortal too.” He had no idea—insanity, he supposed—why he was aggravating Wynter like he was. She sure had a fine temper, and she was very expressive with her hands. Like the way she doubled up her fist at him. “You can’t hurt me.” “Why not?” He told her. “I’m not going to be your mate. It has nothing to do with this shit…stuff going on with the dragons, but I’m bad luck. I don’t even like to be around my mom so much—I don’t want her to be dragged into my trouble.” “I’m sure that it was all because you were going to meet me this way.” He didn’t even glance at the dragons, fearful that they’d tell him that that wasn’t it. “We’re going to get this all cleared up, and once we do, then you and I will live happily ever after.” “You’re certifiable; you know that, don’t you?” He grinned at her. “You’re not charming either. No matter how many other women have told you that. As a matter of fact, why don’t you go out and find one of them now? I’m sure they’ll be thrilled to see you.” “I’m not leaving you. We have a lot to talk about.” She said that she was done talking to him. “I’m sorry that you feel that way, Wynter. But there are a great many things going on that we have to figure out. Like, why were you created with a dragon on your leg and not your back? Who were you parents? Where were they for all those decades before you were born? There are a great many things that we have to figure out. Plus, keeping you safe needs to be a priority—I don’t want anything to happen to you. For some reason, and I don’t know why we’ve never thought of this before, someone wants you to be in prison. To get you alone, perhaps? I don’t know. But it bears talking about.” Clara stood and so did Tristan. “I need to use the restroom. I don’t know that I’ll return here, because I think that Lord Manning is correct. You both need to talk things out. In the meantime, I’ll be making arrangements for a hotel or someplace that we can stay until we get those answers.” “I have a large house that we can all live in together.” Clara told him that was all right, but she could find something. “I insist. I can keep an eye on you both, and if Wynter wants, she can become her dragon. There is plenty of room for that too.” Clara left and Tristan stayed where he was. Wynter was jumpy enough without him lying on the bed with her like he wanted. Instead of talking to her about anything serious, he started telling her about himself. “I’ve been around for a very long time. When we were born, we were dragons; the world was a much different place than it is now. We, the dragons, blackened the skies when we were around. Helping out our human friends was easy for us. Then they realized that we were worth much more dead than alive.” Wynter told him she was sorry. “Thank you. My mother, she’d been killed some months before my father gave his life for us to be human. And since then, we’ve been trying our best to blend in with humanity so they’d not kill us.” “I don’t understand any of this.” He said that he understood. They both looked at the dragons. “Do you really think it’s possible that I could turn into a dragon? Being that size would make people back off from me a little, don’t you think?” “You’ll be much larger than them.” She looked at him. “Wynter, I know this is a great deal to throw at you, but we really do need some answers. Mostly it has to do with why you’re a dragon that no one told us about. Why are we paired with matching dragons? My head is overwhelmed with all this. I can’t imagine what is going through yours right now.” “My wound is healed. I’m betting if they remove this cast that I’ll be all right there as well. Is that part of the magic?” He nodded. “I’m terrified out of my mind right now. And all I can think about is you wrapping me up in your arms and holding me. Not that I’m asking you to do that, but I just need one thing to go normally. I really could use a dose of normal about now.” “I’m afraid that went out the door with yesterday’s wash.” They both laughed. “Come on downstairs and we’ll have something to eat, and talk. I’m sure that Winnie or Carson has the others tied to a chair or something to keep them away.” “I don’t have anything to wear but this gown from the hospital.” She looked down at herself. “What I wouldn’t give for a nice thick pair of socks and some warm pants and a too large sweatshirt.” Before he could tell her to watch what she wished for, she was dressed in what she’d said. He had to admit, he thought, she certainly looked more comfy. When he started to tell her that she could do that, to change out of her outfit too, Wynter put her hand up. “I don’t want to talk about it. Nothing happened, all right? Please?” He nodded at her. “Good. I got dressed, and now I’m going to eat. I’m sure nothing will pop out of the kitchen in front of me, will it?” “I have no idea anymore.” She nodded and took his hand. The dragons said that they’d see them downstairs, as they needed to stretch their wings. “Do you want to watch them fly? It’s beautiful, and perhaps—” “No. There are no dragons. I’m visiting an old friend and I had a frightful dream, that’s all.” Tristan laughed and she grabbed his balls in her hand. “Don’t make me have to test that theory of yours

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identification of taxa, and organic material analyses. ### Stream water {#Sec11} At Stora Göljån, stream water was sampled on a monthly basis. Before the flashflood, the samples were collected from a bridge just downstream the benthic macroinvertebrate sampling site. After the flashflood, this stream channel was clogged, and the samples were taken from shore just downstream the new benthic fauna sampling site. The water was collected in rinsed polyethylene bottles and before 2009, sent for chemical analysis to the SWEDAC accredited MEANA laboratory in Uppsala. From January 2009 and onwards, the samples were sent to the laboratory at the Department of Aquatic Sciences and Assessment, SLU for chemical analysis. Except for PO~4~^3−^ and TP, the two laboratories used the same analytic methods, and SO~4~^2−^ and Cl^−^ were in fact analyzed at SLU ([@CR37]) throughout the monitoring period. At MEANA, PO~4~-P and TP were manually analyzed in a 5-cm quartz cuvette. Statistical analyses {#Sec12} -------------------- The Aneboda IM SW, GW, and stream water N concentration time series were separated into Reference (before January 8, 2005), Storm-felling (January 8, 2005--December 31, 2007) and Bark beetle periods (after January 1, 2008). Differences in N concentrations between periods were tested by the Kruskal--Wallis test followed by a post hoc comparison for each pair using Bonferroni-corrected Wilcoxon test (JMP version 10.0.2d1). Due to the restricted number of observations on TN during the storm-felling period for SW (*n* = 3--15 per season and soil stratum) and GW (*n* = 3 per season and sampling site for all N compounds), we have not tested for seasonality. In total, eight metrics describing the macroinvertebrate assemblage structure for each sampling occasion (spring and autumn) and year were calculated, and due to statistical differences in macroinvertebrate metrics between seasons, further analysis was separated by season. However, due to the lack of autumn samples and the limited number of spring samples prior to the catastrophic event, we were not able to perform any statistical tests on differences between metrics before and after the storm. The eight biological metrics were used to analyze possible changes in diversity and composition of macroinvertebrate assemblages. Taxon richness was selected as a qualitative measure of changes in assemblage diversity. In addition, assemblage diversity was calculated as Shannon (Shannon and Weaver [@CR35]) and Simpson (Simpson [@CR36]) diversity as well taxon distinctness. The latter is a diversity measure based on the relatedness of the species within a sample (Warwick and Clarke [@CR47]). Further, a detrended correspondence analysis (DCA) was performed to show temporal changes in taxonomic composition. DCA is an unconstrained ordination technique, which finds the main factors/gradients in large, species-rich, but usually sparse data matrices (ecological community data). Simple linear regression analyses with metrics versus time were performed to display possible changes in metrics over time, especially focused on the time after the event. To evaluate the relationships between macroinvertebrate assemblages and environmental factors and to assess which factors that can explain changes in the species assemblage of benthic macroinvertebrates over time, a canonical correspondence analysis (CCA) was performed with physicochemical data, including organic substrate parameters expressed as AFDW (Table [2](#Tab2){ref-type="table"}).Table 2Minimum, maximum, and mean (±1 SD) values of water chemistry and organic substrate (AFDW mg) variables across all years, but separated in autumn and spring samples at Stora Göljån, used in the CCAAutumnSpringMinMaxMeanSDMinMaxMeanSDpH56.596.210.475.416.56.120.30Conductivity (mS m^−1^)0.841.921.220.220.841.671.160.22Alkalinity (meq L^−1^)−0.020.060.040.0200.060.030.02Absorbance (420 nm)0.030.070.050.010.050.120.080.02TOC (mg L^−1^)1.54.62.450.803.25.484.30.76NH~4~-N (µg L^−1^)274.201.520103.92.38NO~3~-N (µg L^−1^)0197123.547.23015677.238.1TN (µg L^−1^)90245192.340.050357193.473.4PO~4~-P (µg L^−1^)185.761.540147.022.9TP (µg L^−1^)5199.613.0403517.89.6Ca (mg L^−1^)01.320.910.4501.800.980.5Mg (mg L^−1^)00.190.110.0500.180.110.05SO~4~ (meq L^−1^)0.020.030.030.010.010.040.030.01Organic substrate Detritus (mg AFDW)19.8202.652.847.316.50180.5261.943.34 *Fontinalis* sp. (mg AFDW)07.741.052.42096.912.331.8 *Sphagnum* sp. (mg AFDW)0000026.021.726.5 Periphyton (mg AFDW)035.47.189.58035.99.0410.05 Other (mg AFDW)0249.362.583.2043172.8114.9 Metrics have been calculated using Asterics version 3.3.1 (<http://www.fliessgewaesserbewertung.de>); DCA and CCA have been performed using CANOCO 4.5 (ter Braak and Smilauer [@CR41]); and regressions have been made using JMP 10 (SAS [@CR32]). Results {#Sec13} ======= Tree layer effects at Aneboda IM {#Sec14} -------------------------------- Before the storm, the fraction of dead Norway spruce trees \[standing and downed, \>5-cm diameter at breast height (dbh)\] in respect of the monitored plots was about 22 % (Fig. [5](#Fig5){ref-type="fig"}). The year after the storm, this fraction increased to 32 %. In the following years, the number of dead Norway spruce trees annually increased by ≈5 % mainly as an effect of bark beetles. During the scheduled inventory in 2011, several of the most affected plots were not monitored, as it was considered too dangerous to enter the maze of fallen logs. The two extra inventories of bark beetle infestation in 2009 showed that bark beetles affected basically all spruces \>5 cm dbh. Only 0.7--2 % of the trees were unaffected (total number of investigated trees, *n* = 1053). Half of the trees had minor damages (class 2). Most of these trees did not change class between the two surveys. Between 2006 and 2008, 17 % of the Norway spruce trees died. During the summer 2009, another 8 % of the trees died. In 2011, we recorded that yet another 11 % of the Norway spruce trees had died. However, this percentage should be actually higher as several plots with numerous dead and downed trees were excluded from the 2011 inventory due to safety reasons. The highest impact by the bark beetles was on larger trees. For Norway spruce trees with diameters \<20 cm, the fraction of dead trees per plot was about the same in all the four inventories. For larger trees, the fraction of dead trees increased drastically in the 2011 inventory (Fig. [6](#Fig6){ref-type="fig"}).Fig. 6Fraction of dead Norway spruce per trunk diameter class at inventories for different years at Aneboda IM Nitrogen effects at Aneboda IM {#Sec15} ------------------------------ There were no indications that the storm felling in January 2005 caused any increased N concentrations in SW in the peaty riparian soils (Fig. [7](#Fig7){ref-type="fig"}; Table [3](#Tab3){ref-type="table"}). In the B-horizon, however, the NO~3~-N concentration was significantly higher after the bark beetle attack (*p* \< 0.05) (Fig. [7](#Fig7){ref-type="fig"}; Table [3](#Tab3){ref-type="table"}). This affected the TN concentrations as well with significantly higher TN concentrations in the order: Reference \< Storm felling \< Bark beetle period (Table [3](#Tab3){ref-type="table"}). Except for at 3.2-m soil depth in the intermediate zone, showing significantly lower NH~4~-N concentrations during the storm-felling period, no differences between periods were found for N in GW in the recharge areas and intermediate zones. In the discharge area, however, significantly higher NH~4~-N and TN concentrations were found during the bark beetle period both at 1.0-m and 2.0-m soil depths, while excess NO~3~-N

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(0, -90, 0), turn-left (90, 0, 0), turn-right (-90, 0, 0) Shake normal normal </COMMENTFIXEDWIDTH> </COMMENT> <COMMENT> <COMMENT_HEADING>* Meanings of Presets</COMMENT_HEADING> <COMMENT_DATA> "Happy" means a 180 degree semi-circle, clockwise from the 3 o'clock position. "Sad" means a 180 degree semi-circle, clockwise from the 9 o'clock position. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Maximum Gesture Size</COMMENT_HEADING> <COMMENT_DATA> There is no formal maximum size for a gesture, for example a circle gesture could require the user to move several times round the circle. However if the user draws such a gesture very slowly it's possible that too many stylus move points could be generated, and the gesture wouldn't be detected. The plugin has been tested with a circle gesture from 0 to 720 degrees and taking approximately 6 seconds to draw without problem. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Compatibility with other APIs and settings</COMMENT_HEADING> <COMMENT_DATA> Gestures may behave strangely on some devices if you are using Finger Scrolling or if you have any of the debug buttons displayed like the 'backbutton' or 'forwardbutton'. Particularly with the IE engine the screen will also scroll behind the gesture or the diagnostics will not persist respectively. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Common Pitfalls</COMMENT_HEADING> <COMMENT_DATA> Do not use alert boxes within the Gesture-Detected Callback, doing so will steal focus from the gesture region. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Out-of-range Values</COMMENT_HEADING> <COMMENT_DATA> Any parameter values out of the allowed range will be limited to the nearest allowed value. E.g. giving a sensitivity greater than 100 will use 100. Numeric parameters given as text will be treated as zero. </COMMENT_DATA> </COMMENT> <COMMENT> <COMMENT_HEADING>Diagnostics</COMMENT_HEADING> <COMMENT_DATA> Note that diagnostics exist only for the purpose of understanding and evaluating the various parameters. They should not be enabled in the release version of the code. They may also not display correctly in every circumstance, e.g. when scrolling, or for certain sets of parameters, e.g. for nearly vertical linear gestures. Diagnostics are not available for Tilt and Shake gestures. </COMMENT_DATA> </COMMENT> </REMARKS> <EXAMPLES> <EXAMPLE> <DESC> Create two gestures: a default left to right gesture with ID 'swipe', and a hold gesture at the top left of the screen which will fire one time after 500 milliseconds with ID 'press'. The Javascript function onGesture() is called when either gesture is detected. </DESC> <CODE> <META HTTP-Equiv="gesture" Content="type:linear"> <META HTTP-Equiv="gesture" Content="id:swipe"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture" Content="type:hold"> <META HTTP-Equiv="gesture" Content="center-x:60"> <META HTTP-Equiv="gesture" Content="center-y:60"> <META HTTP-Equiv="gesture" Content="radius:60"> <META HTTP-Equiv="gesture" Content="delay:500"> <META HTTP-Equiv="gesture" Content="interval:0"> <META HTTP-Equiv="gesture" Content="id:press"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture-detected" Content="url('Javascript:onGesture('%s','%s');')"> </CODE> </EXAMPLE> <EXAMPLE> <DESC> The following example deletes a gesture via a javascript function. </DESC> <CODE> function deleteGesture(gestureID) { gesture.id = gestureID; gesture.delete(); } </CODE> </EXAMPLE> <EXAMPLE> <DESC> Create 3D gestures: a tilt gesture that is called when the device is placed in upright position and a shake gesture. The Javascript function onGesture() is called when either gesture is detected. </DESC> <CODE> <META HTTP-Equiv="gesture" Content="type:tilt"> <META HTTP-Equiv="gesture" Content="id:swipe"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture" Content="type:shake"> <META HTTP-Equiv="gesture" Content="id:shake"> <META HTTP-Equiv="gesture" Content="create"> <META HTTP-Equiv="gesture-detected" Content="url('Javascript:onGesture(%json);')"> <script type="text/javascript"> function onGesture(jsonObject) { var html = "<b>Gesture Detected: </b>" + jsonObject.id + ""; gestureOut.innerHTML=html; } </script> <DIV id="gestureOut">Gesture Output will appear here</div> </CODE> </EXAMPLE> </EXAMPLES> <ADDITIONAL> <PLATFORM>All supported devices. On Windows the tilt and shake gestures are supported only on MPA3.0 devices.</PLATFORM> <APPLIES>Transient - any changes made by changing parameters will be lost when navigating to a new page.</APPLIES> <REQ>Linear, Circle and Hold gestures require a touch screen.</REQ> <VER_INTRODUCED>1.0.0</VER_INTRODUCED> </ADDITIONAL> <SEEALSO> <TOPIC RELPATH="../Getting Started/">GesturesOverview</TOPIC> </SEEALSO> </FUNC> </HELPPAGE> There are many good shows to watch on the Internet, like سكس في الحمام or سكسنيك من خلف. Do you like سكس أغتصاب or سكس في الحمام better? With the advancement of high broadband speeds, high definition streaming video is possible. Here on Shin SVS, you can search for سكس دينا رقاصه and سكس أغتصاب streaming Videos from popular video portals on the Internet like Youtube. Have a good time!Protection of femoral neck taper in revision of acetabular component. In hip revision restricted to the acetabular component, the taper of a modular stem is in constant danger of scratching. We used a plastic syringe to protect the taper of the femoral component. A plastic syringe of appropriate size remains well in place and offers a novel and inexpensive protective device for the taper of the femoral component available in every operation room.> Initial Number - counting starts here! > BBC 1 is the flagship television service of the BBC. > ITV 1 was the flagship television service of ITV, but it reverted to simply ITV in 2013. > Sky 1 is the prime general entertainment service of Sky Television. > Radio 1 is a radio service from the BBC, aimed at the younger generation. > Formula 1 is the highest level of motor racing regulated by the FIA (Fédération Internationale de l'Automobile). > Humans have 1 nose and 1 mouth, and 1 each of most vital organs.> A "one-man-band" is an individual who plays a number of

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the fifth (41. 8%), the two quality and quantity. Consumed together, the three points to thrown into space isn't an easy thing, should have the forty percent three-point shots have to create his own shots, this how tired! The most precious is, no make a difference when and where, and how to make simple moves, garage has a superior percentage. It is no wonder the manager of the a warrior when Bob myers recently told the Associated Mass media said: "as long seeing that it's garage, to find the ball is reasonable. ". Finals past season, Arsenal's performance [url=http://www.kdshoes.us.com]kevin durant shoes[/url] isn't very ideal, although the info well, but the efficiency is not high, and his again pass error, defensive irvine was manufactured key 3 points have grown to be a "black spots" moment, apparently, in hope that within this to prove himself. Simply no, after the opening, the three points inside database and didn't hit two shots, on this contrary, the knight about three points would hit a lot of over there. Garage or focus on defense, he para which include lebron, Irwin, JR., continues to be people already, also have successful prevention. In transferring, did well in your Treasury, the ball to your teammate are fed properly, but Mr Chu in a number of opportunity attack. 04 seconds left within the first quarter, garage dribble for the frontcourt, rhythm, but he could be confident the take a few steps away from the three-point line and it's necessary to make [url=http://www.curry-shoes.com]curry shoes[/url] actions, the ball! This can be the warriors in the very first 3-pointer today. Soon, the Treasury and using second chances for the right side of the beds base again in a 3 details! It is worth mentioning how the opening, the garage suitable arm was wearing a new black gear, it is also because his right elbow inside the game before the old injury carries a relapse, however, with the sport, he has to take off protective devices. Gear, this indicates, has affected the deal with, before he took off once i feel much better. Within against lebron James, the defense does very well in the Arsenal, but after he was lebron was a little daughter knocked out, the referee has [url=http://www.stephencurryshoes.com]stephen curry shoes[/url] blown the garage preventing foul, garage on the soil is various, make action on the referee said lebron knee. In breakthrough, garage is usually a difficult moves, a myriad of people all the approach up his defense, including lebron, but Treasury first in all kinds of dazzling dribble move Thompson, after air and rival crash cases, the hard in order to score. Throw three points isn't the whole garage everyday work, and don't forget about, Stephen curry is the team in assists in addition to steals, he averaged 6. 7 assists from the regular season, 14 in the league and the playoffs [url=http://www.stephencurryshoes.com]stephen curry shoes[/url] can be averaging 9. 3 assists because league the first! Let's imagine an image, 40 minutes per game inside the Treasury, attack launched lots of times, there are always several ball he wasn't within the outside, but the soccer ball inside, attracted a twice... What will happen and then? There was a man he'll tell you the answer, [url=http://www.curry-shoes.com]curry shoes[/url] he called clay : Thompson, from the older state warriors, he made there is much surprise 211 3-pointers, finished third inside the league, and that 211 3-pointers, 68 comes from the assists of Stephen curry. 12-13 time of year to contrast the storage area and ray Allen inside '05 -' 06 : Allen into 269 3-pointers, and he could be the Seattle supersonics. That year, Allen's 269 involving 653 three-point shots, chance 41. 2%, as Stephen -- 272 of 600 photographs in his Arsenal, as high as 45. 3%; That yr, Alan ball attack build 3 ratio is below a quarter, compared along with 38. 6% in data bank; That year, Allen's assists the number 3. 7, less compared to the Treasury for three helps. So the outline, the image of alternative 3-pointers hand down the garage outline: he not merely completed the sharpshooter backdrop, his teammates for the creation of free-throw options into; He will also look for opportunities as well, through the ball discovery, stopped for no allows 3-pointer of shots. Additionally, he also can move assists, "create" another glass pitcher - clay - Thompson! Not merely can catch vote, will urgent stopped, can develop more opportunities to other folks, this star, unique! I'm [url=http://www.kdshoes.us.com]kd shoes[/url] afraid, just use "striker" two words are actually unable to define Stephen curry, also have to be in with a new "great" rhetoric. Half-court finished,[url=http://www.stephencurryshoes.com]stephen curry shoes[/url] the garage 12 details and 4 rebounds 6 helps, Owen 17 rebounds, 2 assists 1 contains the upper hand slightly. But as knight defeat in the second half, even their one-on-one hit his things. In this series, OuWenBen should have certain advantages in counterpoint, such as finals last year, because season of Christmas competitions, with their strong particular fortunes turned. But today the warriors of the changes, let knights staggered, also let like one-on-one hit Owen [url=http://www.curry-shoes.com]curry shoes[/url] to search for the rhythm. Actually, today more often than not was clay - Thompson The almighty Owen, although Owen hit a dead before him, but clay height reach or up to a point, limits the Owen's invasion. In only a few times facing single singled out inside his Arsenal, although Owen possesses good performance, but also it's hard another for a knight. Total play, scored 28 points 6 rebounds and 10 assists inside the Treasury, 6 of 11 three-point [url=http://www.kdshoes.us.com]kevin durant shoes[/url] photographs. 24 points and 3 rebounds, a couple of assists, Owen has scored 17 points within the first half, he scored seven points within the second half. Facing the big four in the mighty, and only Jordan Owen in one-on-one win garage have chances, but today's garage to try and do better. Garage underneath the [url=http://www.stephencurryshoes.com]stephen curry shoes[/url] second dribbling is toward the switch on the left side with the body without any slowdown, the footsteps choiceness and quick, soon arrived at the position you would like to go. Unlike most pitcher like center of gravity down, then struggled to jump to complete, the garage action a lot more concise. Don't waste any hard work, just jump off the bottom, slightly triggered his firing action instantly. "He is not only the most pure great scorer, he even gave shot two words to make the definition, the whole shooting art played a new revolutionary role. "The bobcats head scout work Adam - Mr Libby said Treasury. Counter frames in 6 a few minutes and 31 seconds, garage from his upper body slightly next point position organized the ball, the index finger as well as middle finger instinct to get gaps in the plastic ball center. His hand gently lifted back, remaining his palm the basketball, but still control between his fingers. His right arm into all of the joints is close to help 90 degree Angle, in the shoulder to the elbow, from the elbow towards wrist, from wrist to consider, as if a cafe waiter in carrying the tray. Glen Davis clippers, 289 - pound in the front, [url=http://www.curry-shoes.com]curry shoes[/url] need to speed up their action in the Treasury, since the childhood to lay a great foundation for complete to garage in different state, the right arm and shooting are able to keep perfect posture and durability. And in addition to master hand movements, garage features a precise shot needed one more factor: enough deep muscle tissue memory. Shooting touch isn't a proper adjective, any player, able to throw a good shooting there is yet one secret to all - month after month, year after year practice, until a set involving complex dynamic chain implanted into muscle tissue. Garage never resist like monks meditate boring exercise, it also helped while he graduated from high school, eventually grow into a separate leading little-known Davidson college or university NCAA elite last seven. "Game changing, there is no time to [url=http://www.kdshoes.us.com]kevin durant shoes[/url] you feel about your own shooting action is correct, " curry explained, "you can only depend on their daily at it ground building muscle ram, hit and believe that any of us can. We're so many practice in training, to be able to the game, you can make use of instinct to react. But if it is not in the right way, the game will feel very strange. ". Finals very last season, Arsenal's performance [url=http://www.kdshoes.us

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those large, brightly lit stores, so vast they are disheartening, and bought with him things other people bought to have a good time together, as though by doing that we would have a good time, whereas I had no illusion that I would enjoy myself, or maybe I did think I could achieve something that would feel, at least for a little while, like a good time simply by going through the motions of it, that if I just carried on like that, my mood would suddenly change, and what had not been enjoyable would become enjoyable. Now I would like to be in that room again, on that night. I am curious to see what he would say and what I would answer, because I have forgotten so much of the way he talked and the things he might think of saying to me. Now I would bring so much interest to the meeting with him that it would be full of a kind of life it did not have then. There was no table where we could play cards, so we sat on the carpet by his bed. We drank the beer, ate the chips, and played gin rummy. The game was not interesting. I might have known, if I had been willing to think about it, that I could not hope for anything from the game itself, because if there was boredom between us, there would be no tension in the game either. We played on and on, as though trying to force some interest from it. We drank more beer than we wanted, or at least it was more than I wanted, and were not affected by it either. The alcohol seemed to have no more power to intoxicate me than the game had power to interest me, and the situation was not changed by it, as I had hoped it would be, knowing that alcohol could usually change a situation at least a little. We ate the chips and maybe other things as well before the chips, or maybe we had had something odd or excessive earlier, for dinner, because when we finally went to bed, I began to feel sick, and I lay awake feeling sick, and then my sickness became so bad that I kept going into the bathroom and sitting on the floor next to the toilet, my arms on the toilet seat and my head on my arms, and then on the toilet, and then down on the floor again next to the toilet, for most of the night. He woke up slightly, once, but did not seem to notice that I was going back and forth so often or was awake for so much of the night. The next day was his birthday. We went to a movie. After the movie, we went home to my house, ate thick sweet cake and ice cream, and sat on the foot of my bed while across the room, so large and empty that the bed at one end, and the piano, the card table, and the ugly metal chairs at the other seemed small on the expanse of dark tile floor, Madeleine, sitting on one of the hard chairs, read aloud to us in the light from one of the bare bulbs attached to the white plaster wall long, complex horoscopes from a magazine. Again I was uneasy, and sensed that without the food and Madeleine's company, there would have been emptiness between him and me, and boredom, that the presence of Madeleine, in fact, who was so separate from us, drew us together a little, at the same time that what she was reading was so entertaining, and beyond that, her own reactions to it were so sharp. I ate too much, and I laughed too much. But the food held most of my interest and attention as long as it lasted and I was restless as soon as it was gone. What did boredom mean then? That nothing more would happen with him. It wasn't that he was boring, it was that I no longer had any expectations for this companionship with him. There had been expectations, and they had died. And why did that boredom make me so uncomfortable? Because of the emptiness of it, the empty spaces opening up between him and me, around us. I was imprisoned with this person and this feeling. Emptiness, but also disappointment: what had once been so complete was now so incomplete. * * * The evening before I left on my last trip contains another memory that is difficult, not so much because of my bad feelings about him, I think, as because of a combination of other things: the awkward spaces and ugly concrete walls of the barnlike building where the reception was held, the sickening sweetness of the cheap white wine, the rain afterward, the bare lawn outside, with no plantings on it at all, and the word "reception," which I don't like. I was moving from one person to another, with a glass of that sweet wine in my hand, looking through the crowd from time to time, when suddenly I saw him standing there with a few of his young friends. I did not expect to see him, though now I can't think why I wouldn't have talked to him about the reception. This is the sort of question that bothers me the most, because I will never have an answer for it—what our relations were at that point, if I was planning to do something without him and without even mentioning it to him. Maybe that was not unusual for us, but it seems especially strange to me in this case, since I was leaving the next morning. I can't remember which friends he was with, or if I even noticed who they were, since I didn't care, and I can't remember if I went over to him as soon as I saw him or, remaining a few yards away, caught his attention and waved to him and continued to talk to other people, or didn't try to catch his attention but simply watched him and kept track of where he was in the room. The last seems the most likely to me, maybe because this is what I have believed all these years. But it was also something I would be likely to do, given the reaction I had when I saw him, a reaction I do remember unmistakably. It was a feeling of absolute displeasure to see him there, as though he were a hostile element in that place, a thing that intruded where it didn't belong, so that as I watched him among the moving figures, over the shoulders of the other people in the crowded place, those same features of his that had held such a positive attraction for me not long before, and that would exert such a fascinating force again not long after, were just then repugnant to me, blunt and deadly, primitive and vicious, without intelligence, without humanity, the color of clay. Rain was coming down hard and a few people gathered by the open door, preparing to run to their cars. Although I don't know how I came to stand by the door with him, I did go with him to my car, the two of us running across the sodden lawn under my umbrella or my raincoat, and I drove him the short distance to his own car. I certainly remember the spongy grass under my feet better than I remember what I said to him, or what he said to me. I was on my way out to dinner, and he was going off to some place where his friends were giving him a birthday party. He said he would come to my house late in the evening. By the time he came, I had been at work several hours on a job I had to do before I left in the morning, and although it was already late by then, I was not finished. He went to bed at the other end of the room and fell asleep. I worked on, impatient to be done with what had turned out to be much more tedious than I had thought it would be. I was checking a friend's translation, and I was doing it as a favor. The friend never really thanked me later, or not in any way proportionate to the amount of work I had done or the awkward moment when I had had to do it, though of course it wouldn't be fair to expect her to know how awkward that moment was, especially since even I did not know it was the last night I would spend with him. I finished and went to bed. He woke up, and then we talked to each other for close to an hour, unusually companionable and relaxed, as we might have been all along, as though we were taking our last chance for it. The next morning we got into his car and he drove me to the airport. I did not see him again until I came back more than four weeks later, when he met me at the same airport and we got back into the same car. He waited until we were on our way up the highway to begin telling me that everything had changed. The distance in him was enough to let me know something had happened, though he had said nothing about it in the corridors of the airport or by the revolving tables of luggage. The distance was there because he had already begun a different way of being with me, whereas I was still in the old way of being with him. * * * I lost most of another day of work yesterday, because Vincent and I took his father to the county fair. We put a cap on him because it was a blistering hot day, and as we wheeled him around he peered out at everything attentively from under his visor. We took him to see the sheds of cattle, sheep, rabbits, and poultry, and the rubber tires of his chair rolled pleasantly over the fresh sawdust. A goose put its beak to the wire grille of its cage and honked at him and he kissed his hand back to the goose. I don't know what he was thinking. I suppose we were trying to entertain him with a spectacle more unusual than his

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than talk about the reproductive system of human beings, some of them talk about peacocks and its tears.” Yup, we definitely need to re-haul the way India views sex-education, as one Indian classical dancer takes on the challenge.What nonsense. People who buy Tabasco sauce do not travel on public transport in South Africa - they drive. And how exactly is someone driving past going to experience the heat factor? Answer: they can't.# Copyright 2017 The TensorFlow Authors. All Rights Reserved. # # Licensed under the Apache License, Version 2.0 (the "License"); # you may not use this file except in compliance with the License. # You may obtain a copy of the License at # # http://www.apache.org/licenses/LICENSE-2.0 # # Unless required by applicable law or agreed to in writing, software # distributed under the License is distributed on an "AS IS" BASIS, # WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. # See the License for the specific language governing permissions and # limitations under the License. # ============================================================================== """ResNet model. Related papers: https://arxiv.org/pdf/1603.05027v2.pdf https://arxiv.org/pdf/1512.03385v1.pdf https://arxiv.org/pdf/1605.07146v1.pdf """ from __future__ import absolute_import from __future__ import division from __future__ import print_function import tensorflow as tf class ResNet(object): """ResNet model.""" def __init__(self, is_training, data_format, batch_norm_decay, batch_norm_epsilon): """ResNet constructor. Args: is_training: if build training or inference model. data_format: the data_format used during computation. one of 'channels_first' or 'channels_last'. """ self._batch_norm_decay = batch_norm_decay self._batch_norm_epsilon = batch_norm_epsilon self._is_training = is_training assert data_format in ('channels_first', 'channels_last') self._data_format = data_format def forward_pass(self, x): raise NotImplementedError( 'forward_pass() is implemented in ResNet sub classes') def _residual_v1(self, x, kernel_size, in_filter, out_filter, stride, activate_before_residual=False): """Residual unit with 2 sub layers, using Plan A for shortcut connection.""" del activate_before_residual with tf.name_scope('residual_v1') as name_scope: orig_x = x x = self._conv(x, kernel_size, out_filter, stride) x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, kernel_size, out_filter, 1) x = self._batch_norm(x) if in_filter != out_filter: orig_x = self._avg_pool(orig_x, stride, stride) pad = (out_filter - in_filter) // 2 if self._data_format == 'channels_first': orig_x = tf.pad(orig_x, [[0, 0], [pad, pad], [0, 0], [0, 0]]) else: orig_x = tf.pad(orig_x, [[0, 0], [0, 0], [0, 0], [pad, pad]]) x = self._relu(tf.add(x, orig_x)) tf.logging.info('image after unit %s: %s', name_scope, x.get_shape()) return x def _residual_v2(self, x, in_filter, out_filter, stride, activate_before_residual=False): """Residual unit with 2 sub layers with preactivation, plan A shortcut.""" with tf.name_scope('residual_v2') as name_scope: if activate_before_residual: x = self._batch_norm(x) x = self._relu(x) orig_x = x else: orig_x = x x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 3, out_filter, stride) x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 3, out_filter, [1, 1, 1, 1]) if in_filter != out_filter: pad = (out_filter - in_filter) // 2 orig_x = self._avg_pool(orig_x, stride, stride) if self._data_format == 'channels_first': orig_x = tf.pad(orig_x, [[0, 0], [pad, pad], [0, 0], [0, 0]]) else: orig_x = tf.pad(orig_x, [[0, 0], [0, 0], [0, 0], [pad, pad]]) x = tf.add(x, orig_x) tf.logging.info('image after unit %s: %s', name_scope, x.get_shape()) return x def _bottleneck_residual_v2(self, x, in_filter, out_filter, stride, activate_before_residual=False): """Bottleneck residual unit with 3 sub layers, plan B shortcut.""" with tf.name_scope('bottle_residual_v2') as name_scope: if activate_before_residual: x = self._batch_norm(x) x = self._relu(x) orig_x = x else: orig_x = x x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 1, out_filter // 4, stride, is_atrous=True) x = self._batch_norm(x) x = self._relu(x) # pad when stride isn't unit x = self._conv(x, 3, out_filter // 4, 1, is_atrous=True) x = self._batch_norm(x) x = self._relu(x) x = self._conv(x, 1, out_filter, 1, is_atrous=True) if in_filter != out_filter: orig_x = self._conv(orig_x, 1, out_filter, stride, is_atrous=True) x = tf.add(x, orig_x) tf.logging.info('image after unit %s: %s', name_scope, x.get_shape()) return x def _conv(self, x, kernel_size, filters, strides, is_atrous=False): """Convolution.""" padding = 'SAME' if not is_atrous and strides > 1: pad = kernel_size - 1 pad_beg = pad // 2 pad_end = pad - pad_beg if self._data_format == 'channels_first': x = tf.pad(x, [[0, 0], [0, 0], [pad_beg, pad_end], [pad_beg, pad_end]]) else: x = tf.pad(x, [[0, 0], [pad_beg, pad_end], [pad_beg, pad_end], [0, 0]]) padding = 'VALID' return tf.layers.conv2d( inputs=x, kernel_size=kernel_size, filters=filters, strides=strides, padding=padding, use_bias=False, data_format=self._data_format) def _batch_norm(self, x): if self._data_format == 'channels_first': data_format = 'NCHW' else: data_format = 'NHWC' return tf.contrib.layers.batch_norm( x, decay=self._batch_norm_decay, center=True, scale=True, epsilon=self._batch_norm

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the connecting member. In this case, the insulating cover of the electrical cover is tightly secured within the recess of the first wall portion of the connecting member. On the other hand, since the width of the recess of the second wall portion is smaller than that of the recess of the first wall portion, the insulating cover is stripped when it is pressurizingly inserted into the recess of the second wall portion, so that the conductor of the electrical wire is brought into contact with the inner surface of the recess of the second wall portion to establish an electrical connection between the electrical wire and the connecting member. As a result, an electrical connection between the electrical wire and the terminal connector is established. In the conventional terminal connector as described above, however, there are disadvantages such as follows. Namely, in the conventional terminal connector, since two processes that mounts the connecting member to the terminal body and connects the electrical wire to the connecting member at the two recesses are required in order to connect the electrical wire to the terminal connector, it is difficult to improve operation efficiency for the connection. Further, in the conventional terminal connector, since the size of the electrical wire is changed, it is required to prepare different connecting members having recesses of different sizes. This means trouble in parts control of the terminal connector since each of these connecting members has bulky nature due to its structure.The measurement of products or materials in tanks or silos is important for inventory control and custody transfer in many industries. Product level monitoring is also important in filling a storage device because overfilling and spillage of potentially hazardous products must be avoided. Similarly, level monitoring can be used to detect tank leakage; e.g., large unattended oil or gasoline storage tanks must be closely monitored for possible seepage which would cause contamination of soil and ground water. Also, as the storage device is filled, the product level must be monitored to avoid overfilling and spillage of the potentially hazardous product. Large unattended oil storage tanks must be closely monitored for possible seepage which would cause contamination of the soil and ground water. The standard practice of measuring the level in a storage vessel is to lower a stick or a rope into the vessel until the product is touched. By measuring the extended length the actual level of the product or material in the tank can be determined. This is usually called "sticking the tank". A quite common example of "sticking the tank" occurs when a gasoline station attendant measures the level of a gasoline storage tank by inserting a calibrated stick into the tank and removing it to see how much of its length is wet. Such a procedure is potentially a potentially very dangerous procedure and vents the tank contents to the atmosphere, which is undesirable. Although many of the newer measuring devices which use the stick or rope concept are automated and quite accurate, such devices typically require a physical intrusion into the storage environment. Such breaching of the tank raises the possibility of the contamination of the storage vessel contents and, depending on the corrosive nature of the vessel contents, could impair or destroy the measuring device. Since the early 1970s, various level measuring devices using radar techniques have been developed to eliminate the necessity of the measuring device touching the storage vessel contents. Typical radar level measuring devices use frequency modulated continuous wave (FM-CW) signal wave forms in which the frequency of the transmitted signal is swept at a constant rate over about 1 gigahertz (GHz) around its center frequency. The reflected signal which, due to the time delay caused by the signal traveling from the transmitter to the storage vessel contents and traveling back to the receiver upon reflection from the contents' surface, will be at a different frequency than the presently transmitted signal which, during the transit time, was swept to a different frequency. The difference in frequency between the transmitted and received frequency is an indication of how far the initial transmitted signal had to travel, and thus the distance to the storage vessel contents can be determined. In such systems the minimum resolution of the measurement and the minimum measurable distance is directly related to the sweep width of the transmitted signal. Also, since the return signal is modulated by the chirp, the required detection bandwidth must be wide, decreasing the signal-to-noise ratio and thereby limiting the maximum range. The U.S. Federal Communications Commission (FCC) and international regulations limit the maximum bandwidth of the transmitted signal (at the required power levels to overcome the path loss) to 250 megahertz (MHz). Current equipment, employing fixed sweep rates and fixed sweep lengths, cannot resolve or filter out fractions of return signal cycles. These fractions of cycles occur when the sweep, which is not synchronized with the return signal, reverses or resets before a complete cycle is received. Therefore, these systems exhibit significantly lower signal-to-noise ratios and require at least a 1 GHz bandwidth. What is needed is a method and apparatus to provide an inexpensive and highly accurate measurement for the level of a product in a storage tank or silo using microwave signals given the FCC and international regulations constraint of maximum bandwidth of the transmitted signal of 250 MHz, in a system which can resolve closely spaced echoes and exhibit good signal-to-noise-ratio.Quikr!! Mumbai!! is a free local classifieds website where you can post free advertisements related a business, product and service offered in Mumbai!!. You can post free ads to buy, sell, rent or for charity in Mumbai!!. Find used cars, rent or buy apartments, find a flatmate or even start a tiffin or catering service, hobby or dance class or a fashion boutique in your locality and much more.Fluorescent protein development 1) We are studying photoswitching behaviors of photoswitchable fluorescent proteins and their use in Frster Resonance Energy Transfer (FRET) experiments. This includes an ongoing project to develop photoswitchable yellow fluorescent proteins, photoswitchable red fluorescent proteins, and far-red fluorescent proteins for use in conventional diffraction-limited microscopy as well as super-resolution molecular localization microscopy. 2) We collaborate with Joy Zhao and Peter Schuck on their development of new fluorescence ultracentrifugation techniques. We are surveying numerous fluorescent proteins to better define their oligomerization characteristics. Literature surveys have suggested these characteristics have not been rigorously determined and that unforeseen oligomerization leads to aberrant fluorescent protein behavior. 3) We have an ongoing project to develop improved red fluorescent proteins. Current variants display low fluorescence, slow maturation, and/or oligomerization. Biochemical analyses of wild type proteins coupled with site-directed mutagenesis has led to our discoveries of mRuby variants with much decreased self-association, increased brightness, and faster maturation. Cell biology projects 1) Gaetan Herbomel, a former post-doctoral fellow in the lab of Lawrence Tabak, has started work in my lab and is completing a project to image the localization of Golgi apparatus enzymes using Stimulated Emission Depletion (STED) microscopy, Multifocal Structured Illumination Microscopy (MSIM), Photoactivated Localization Microscopy (PALM), and Stochastic Optical Reconstruction Microscopy (STORM). The multi-color super-resolution experiments have required development new data analyses which we have now implemented. These studies are intended to help in our understanding of where the enzymes are located within the Golgi and what role these locations may play in the enzymatic activity. 2) We collaborate with Jim Kochenderfer (NCI) to study the self-association properties of chimeric antigen receptor (CAR) molecules using our FRET techniques. Instrumentation and imaging development 1) Frster Resonance Energy Transfer (FRET) is a powerful approach to study the interactions of fluorescent molecules. We are developing new approaches which can be performed on a conventional widefield or confocal microscope to image FRET between a donor photoswitchable fluorescent protein, Dronpa, and an acceptor based on a conventional fluorescent protein. The technique which we call photoswitching FRET (psFRET) is based on Dronpas photoswitching properties in the presence and absence of an acceptor. This technique is currently being used to monitor interactions between a number of proteins within living cells. 2) Another FRET based project using psFPs derived directly from the psFRET studies involves imaging homo-FRET by monitoring the anisotropy of the PS-FPs during the photoswitching process as a read-out of protein-protein interactions. This technique, which we called photoswitching anisotropy FRET (psAFRET), differs from measurements of hetero-FRET (energy transfer between two different color proteins) since it monitors energy transfer between copies of the same probe. 3) We are able to use a previously described coordinate-based co-localization (CBC) analysis of PALM/STORM data to develop a plugin which runs within the freely available ImageJ application. It is designed to run with one thread per computer CPU, which drastically improves the computation time. 4) We have also developed a series of image analysis macros that can be run within the ImageJ application to analyze psFRET data. To make this technique more widely useful we have developed an ImageJ plugin that is much more versatile and can be used on almost any dataset for the steps outlined above. In parallel, a second ImageJ plugin was developed to analyze the exponential decay in fluorescence at each pixel as the photoswitchable fluorescent protein switches off. These are available on the ImageJ update site (https://imagej.net/User:Pattersg). 5) We collaborate with the Hari Shroff lab on the development of improved forms of TIRF microscopy. Recent efforts by his lab have resulted in improvements to lateral super-resolution levels while maintain the acquisition speeds necessary for live cell imaging. The emphasis for our collaboration is now to improve axial resolution in this technique.<TITLE>selectionbox - Create and manipulate a selection box widget</TITLE> <H1>selectionbox - Create and manipulate a selection box widget</H1> </pre><

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D Ouspensky(In Search of the Miraculous), who is quoting his teacher George Gurdjieff [pictured below right]: 'Self-observation brings man to the realization of the necessity for self-change. And in observing himself a man notices that self-observation itself brings about certain changes in his inner processes, He begins to understand that self-observation is an instrument of self-change, a means of awakening. By observing himself he throws, as it were, a ray of light onto his inner processes which have hitherto worked in complete darkness. And under the influence of this light the processes themselves begin to change.' You cannot change or reform your false selves, but there is no need to do so in any event. What needs to be done is to ‘dissolve’ your false selves. The first thing to do is to understand the process(an unfortunate word, for it makes it all sound far too mechanical) of formation of the false self/selves. The next thing to do, and keep on doing, that is, practising each day and throughout each day, is self-observation---letting it (whatever it may be) be as it is in you, but being willing for it to move and change. Self-observation of your thoughts, feelings, and actions as they arise or occur---if undertaken with passive detachment and choiceless awareness (that is, with no judgment, justification, analysis, attitude, comment, interpretation, interference, criticism, or condemnation) of what unfolds as your inner and outer reality from one moment to the next---will in time break down your identification with your false selves as a result of the insight gained from the process of self-observation itself. When you truly observe the process of your thinking, and cease being ‘an observer apart from the observed’ (to use Krishnamurti’s words), which means you see the whole movement of your thoughts, and your feelings, as well as your actions, choicelessly in the sense explained above, then the very act of self-observation puts an end to thought. The result? The false selves are dissolved because they are simply the creation of thought, habits of thought, and conditioning---all of them thought. No thought, no false selves---and over time a psychological mutation occurs that is of tremendous depth and profundity. You have become a light unto yourself. Yes, it’s a wondrous thing to behold. Self-change from self-knowledge from self-observation. (Note. The reference to 'self' in the expressions 'self-change' and 'self-knowledge' is a reference to what we actually are as persons among persons. As to the expression 'self-observation,' the word 'self' has an expanded meaning as described above.) In some spiritual traditions this whole process is referred to as ‘surrender’ or ‘letting go,’ with the idea that there needs to be a re-surrender and further letting-go whenever one becomes aware of something---in particular, some false self---that is holding us back from fully being the real person that we are. It doesn’t matter what you call it. The only important thing is that you dissolve your false selves through ongoing---yes, it must be undertaken on a progressive basis---self-observation. I suggest there is no better place to begin than … now! So, start right where you are. Now. Dear Eric: Thanks, once again. I greatly appreciate your comments and best wishes. Now, all the best for those exams. If there is a 'fearful self' or an 'unconfident self' in you, or even an 'over-confident self' (it works both ways), know this---they are NOT you, the person that you (Eric) are. Do not give them power. Watch them come and go, but detach from them. The person that you are can do well for, if you have done what is appropriate, you have within you, the person, all that you need to do well. Get the picture? It is nothing other than recognizing the false as false. We need to do that in order to know, understand, and live from the true---the truth of one's being, and ground of being. Bless you, mate---and I would love to see you and your family over here Down Under one day. I would like that so very much. Ian. COPYRIGHT---TERMS OF USE---DISCLAIMER COPYRIGHT: There is no intention to infringe copyright in respect of any copyrighted material; if any person believes there is or may be an infringement of their copyrighted material on any page of this website please advise me by email and any offending material will be removed immediately. 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Accordingly, no representations or warranties are made or given as to the accuracy or any other aspect of information contained in other websites. Finally, this blog is the personal work of IEJ and has no affiliation with his law firm, his company Ellis-Jones Enterprises Pty Limited, his colleagues or any other person, company or body with whom or with which he is associated including but not limited to the New South Wales Institute of Psychiatry and any and all clients. European Union (EU) laws require that EU visitors to this site be given information about cookies used on the blog. For more information on Google's use of certain Blogger and Google cookies on the blog, including Google Analytics and AdSense cookies, please read Google’s privacy practices and how Google uses data on partner sites. CREATIVE COMMONS This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Australia License. Click on CC logo for details.GSL 32m Cure vs DongRaeGu Solar vs Zest Grand Platypus Open 4h 32m OSC 6h 32m Alpha X Series 9h 32m Zoun vs TIME REGENERATE OPEN WEEKLY… 11h 32m PassionCraft 12h 32m BSL 13h 2m spx vs vOddy Dandy vs LaAbuela TerrOr vs BoA OyAji vs CadenZie King of Battles 15h 32m 2v2 16h 32m Have At You 17h 32m Show More ] OSC 19h 32m The NA Apprentice 20h 32m Holdout Challenge 20h 32m Afreeca Starleague 1d 6h King of Battles 1d 6h KOVA Starcraft Team Lea… 1d 9h Mirzo vs Alluton Naama vs TBD TheMusZero vs WoodedMicrob PuPu vs ZhuGeLiang Mixu vs TBD TBD vs Luolis Enpo vs Welmu BW Jeez Weekly 1d 11h PassionCraft 1d 12h King of Battles 1d 12h BSL 1d 13h Jaeyun vs StRyKeR Casper vs DragOn trutaCz vs Kare babo vs MadiNho BeAsT Cup 1d 14h The NA Apprentice 1d 20h ESL Pro Tour 2

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expected she would die now, but the people holding her simply grabbed her legs and arms and held on. Something hissed against her arm and she thought snake before passing out. Not a snake, she thought when she woke up. The angel and a woman in strange clothes sat beside her bed. The woman said, "I know you're not going to believe this either, but you're in an archival facility in the future. Think of it as a library for people. I'm here to explain your legal standing in our culture." Benedetta wondered how many layers of lies they'd try on her. The fake angel said, "We're trying to learn about the past and we'd like you to help us." The woman said, "We saved your life and brought you into the future. A lot of people are more comfortable if they think they died and are in an afterlife they can understand." Maybe they aren't lying? Benedetta thought this was all too crazy for anyone to try as a lie. Should she pretend to believe it until she could learn more, or just stay confused? "We're sorry, but I don't understand why you bit me," the angel said. "Why so hard?" "You were lying to me. Well, thank you for saving me from dying. I can't believe those French. I want out of here." "We'd like to spare you the culture shock," the woman said. Benedetta didn't know how culture could cause shock. "We've saved your life," the man said. "Not that we expect you to be immediately grateful, or to believe us. Yet. But can you begin to tell us honestly about your life. We really want to know what you saw, how you lived, what your customs were." "I want to see the future first," Benedetta said. Her heart was beating very fast. "You have the right to be treated as reasonably as possible. But I think you should wait," the man said. "Your heart is beating very rapidly." I've been trapped by magicians, Benedetta thought. "I couldn't believe in Purgatory." "Most people from the period of Christianity that had a concept of Purgatory as well as Heaven and Hell would find Purgatory believable. Nobody believes they are good enough for heaven—or at least they don't argue about it. And people are relieved to find they're not in Hell," the man said. "I'm Joseph. You can call me Joe." "But she isn't sure where she is now, are you?" the woman said. "In a camera obscura," Benedetta answered. "Well, sort of," Joe said. "You probably want to get some rest and think about things for a while. All your friends are dead, in the past. If you believe us, this has to be a shock." "What is the year?" Benedetta asked. "By the Christian calendar, 2308," the woman said. "Eight hundred and fucking nine years from 1499," Benedetta said. Benedetta realized she didn't know how to get out of their archival room. What was the difference, 1499 or 2308? They were men and women, like other men and women. She would have to get to know them, then figure out who would bend the rules for her. Until then, she'd tell them as many stories as they'd believe. Joe asked, "You can do subtraction in your head?" He sounded genuinely amazed. "Yeah, I can do subtraction in my head. You think I'm stupid because I'm a peasant girl?" "We would never have thought that," Joe said. "It's that we didn't know women were taught to figure in your time." "Oh," Benedetta said. She decided not to tell them she could read, too. Raped, kicked, and left dying, she'd been brought to some fake purgatory run by creeps who'd out-clevered the Florentines with their toys of light. Purgatory wouldn't have been a good fit. Hell was where Benedetta had expected to find herself on the days when she bothered to believe in an afterlife. Most of the time, she figured dead was dead, so up in the future could be better yet. Living in the future, if she could escape the forgeries of times past in these little rooms, would be another adventure. "I want to see this future." "Your immune system can't handle current diseases. Even immunizations to prevent the diseases might kill you. We can't let you out that easily," Joe said. "Explain that in words I know." "Eight hundred years years isn't genetically that large a spread," the woman said, then spoke further in a strange language. "Look, I'm not stupid. Explain what an immune system is." Benedetta spoke the words as well as she could remember them. The future people seemed surprised for some reason. "I can't explain without you knowing more of our language. We have medicines to prevent diseases, for most of the deadly modern diseases. These are not without risks and while you can ask for them, you need to understand what the risks are. And it's hard to explain any of this in archaic Italian." I'm in prison, with better food, with people to talk to, and without beatings, but it's still prison. "So teach me your language if that will help me understand better." "What was it like being with the army?" Joe asked. "You were a camp follower, right?" "No, I wasn't a common camp woman; I was on the artillery team with my husband." She'd never married Emelio in the church, but they'd been together long enough. The people who'd saved and imprisoned her had another hasty conversation in their language, then Joe said, "Okay, we've suspected that the future could send people into the past just as we can move them out, so that is a possibility here, but there are accounts of women working on gun crews in Burgundy." Benedetta shrugged. These people saved her life, but they weren't interested in setting her free. She wondered what they'd do if she lied and said she was from the future. No, she'd tell them the truth until she had a better idea of what sort of mess she was in. Joe asked, "Where in Italy did you travel? What did you see? We're interested in learning things about how people lived that didn't get mentioned in the written records." "We lived in Milan when we weren't on jobs." They talked among themselves. "Really. Can you show us on a map?" They brought in a map of the streets of Milan, some different than what she'd remembered, and it didn't look like the map Leonardo drew. She found the old Sforza castle where Leonardo had lived, and found the little house near it, and said, "Some years, we lived there. And we visited one of the duke's engineers there a lot." She pointed to the old castle. The future people went nuts for a while in that strange language they were speaking. "Are you talking about meeting Leonardo di Vinci?" Yeah, I'm really from the past; I was really on an artillery crew; Leonardo really tried to seduce Emelio but thought I looked nice in mountain-girl clothes. Benedetta finally said, "Milan didn't have that many first-class artillery crews, and Emelio was cute as well as bright. We spent a lot of time at Leonardo's place. He even borrowed my kid for one of his experiments." "I know someone who'd have so many questions for you," Joe said. "Normally, the people we get didn't know anyone historically significant in the old sense of historically significant." "I will tell you what I know if I can get out of here." Joe said, "Did you use forks for eating at the table and for what and what did they look like? Yeah, the information on Leonardo will excite some people, but what I'm most interested in is the daily life of the past, what wasn't in books." Benedetta remembered how weird forks has seemed when she first saw them at the table. "Saved on water, having your own fork to hold meat. And on fingers eating sticky things." She wouldn't tell them how embarrassed she'd been not knowing how to use a fork when she first saw one. But they were excited that she'd met Leonardo. Um, something to work with there. Man's reputation lasted more than eight hundred years; Leonardo wouldn't have been surprised, though. "If you see the future, it may corrupt what you remember of the past," the woman said. "Did Leonardo's drawing books get passed up to the future?" Benedetta asked. They chattered between themselves again, then said, "Yes, some of them." "What is this culture shock you mentioned?" "Most people from the past would have mental difficulties if they tried to understand our times. Most of the more modern ones, and some of the most archaic ones, finally learn where and when they're living now," Joe said. "They're happiest living in places that most resemble their own times. We try to keep them comfortable." But they don't live long was generally the rest of that statement in Bened

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to produce a variety of compounds with divergent chemical structures^[@CR3]^. Recently, the C~30~ and C~50~ biosynthetic pathways were found in *Micrococcus*, *Corynebacterium*, and *Flavobacterium*^[@CR4]^. Carotenoids can function as photoprotectors, light harvesting molecules, or membrane stabilizers^[@CR5]^. In non-phototrophic bacteria, the main function of carotenoids is the protection of cells from photo-oxidative damage by scavenging harmful agents such as singlet and triplet molecular species produced upon illumination^[@CR1],[@CR6]^. In non-phototrophic bacteria, the control of carotenoid production is classified into three types: constitutive, light-inducible, and cryptic manner^[@CR7]^. We and other groups have been studying the phenomena and molecular mechanism of light-inducible production of carotenoids of phylogenetically different bacteria including *S. coelicolor* A3(2)^[@CR8]^, *Thermus thermophilus* HB27^[@CR9]--[@CR14]^, *Bacillus megaterium* QM B1551^[@CR15],[@CR16]^, *Mycobacterium marinum*^[@CR17]^, and *Arthrobacter arilaitensis*^[@CR18]^. Our study has revealed that LitR/CarH family proteins, a MerR family transcriptional regulator retained by *S*. *coelicolor*, *T*. *thermophilus*, and *B*. *megaterium*, play a central role in light-dependent gene expression^[@CR19]^. Other groups have also reported that LitR/CarH family proteins serve as a photosensor in the light-inducible production of carotenoids in *Myxococcus xanthus*^[@CR20],[@CR21]^. LitR/CarH family proteins commonly contain a DNA-binding domain in its N*-*terminus and an adenosyl-coenzyme B~12~ (AdoB~12~)-binding domain in its C-terminus, and serves as a negative regulator for light-inducible transcription^[@CR13],[@CR19]^. The molecular mechanism of light-inducible transcription mediated by the LitR/CarH family involves the photolysis of AdoB~12~ associated with LitR/CarH due to light, which results in a large conformational change and inactivation of the DNA-binding activity of LitR/CarH^[@CR11]^. LitR homologs are widely distributed in the phylogenetically diverged genera of non-phototrophic bacteria, including gram-negative and gram-positive bacteria, which indicate that LitR/CarH family proteins are general photosensors and have diverse roles in non-phototrophic bacteria. Recently, we have also reported the existence of a novel type of LitR/CarH family proteins in *Burkholderia multivorans* belonging to *Beta-proteobacteria*, which requires a different type chromophore from coenzyme B~12~^[@CR22]^. The wide distribution of LitR/CarH family protein among non-phototrophic bacteria leads to our assumption that other type of light-inducible transcriptional regulators is present in non-phototrophic bacteria. The finding of a novel type of photosensors would deepen insights on bacterial environmental responses. In this study, we performed a wide screen of bacteria exhibiting light-inducible production of carotenoids, which led us to the finding that some groups of gram-positive bacteria including *C*. *glutamicum*, an amino acid producer, exhibit photo-dependent production of carotenoids. The evidence indicates that a light-induced MarR family regulator CrtR, is distributed to some groups of *Actinobacteria* and is involved in the light-inducible expression of *crt* biosynthesis genes. Results {#Sec2} ======= Light-inducible yellow-color pigment production in bacteria belonging to the order *Micrococcales* {#Sec3} -------------------------------------------------------------------------------------------------- We previously reported that a number of *Bacillus* spp. isolated from soil showed light-dependent production of carotenoid on rich LB medium^[@CR15]^. Our genetic and biochemical study of *B*. *megaterium* QM B1551 revealed that LitR in complex with B~12~ serves as a photosensitive transcriptional regulator to control the expression of *crt* biosynthesis genes in a light-dependent manner. Here, we used several media including not only LB but also 10-fold diluted LB medium (1/10 LB), 1/10 LB containing 1% glucose (1/10 LBG), and R2A medium to more widely screen bacteria exhibiting light-inducible yellow-color pigment production (see Materials and Methods). We isolated a number of bacteria from various environmental source including biotope, paddy field, forest soil, bran pickled, snow, residential land, and cattle manure in Japan. Of these, bacteria showing white light-dependent pigment production were subjected to the phylogenetic analysis based on DNA sequence of the 16S rRNA gene. As summarized in Table [1](#Tab1){ref-type="table"}, a total of 24 strains out of approximately 1,100 isolates exhibited light-inducible yellow-colored pigment production. The number of the isolated photo-responsive bacteria was 1 strain out of 121 (0.8%) with LB medium, 7 out of 526 (1.3%) with 1/10 LB medium, 14 out of 361 (3.9%) with 1/10 LBG medium, and 2 out of 92 (2.2%) with R2A medium. The isolates mainly belonged to the order *Micrococcales*, a high G + C gram-positive *Actinobacteria*, including the genus *Arthrobacter*, *Leifsonia*, *Microbacterium*, *Brevibacterium*, and *Agromyces*. As minor groups, *Bacillus*, *Sphingobacterium*, and *Simplicispira* genus were also isolated. All isolates exhibited \>99% sequence identity with the known species affiliating to those bacterial taxa. This result indicated that 1/10 LB and 1/10 LBG medium were suitable for the isolation of photo-responsive *Micrococcales* bacteria.Table 1Phylogenetic characteristics of isolates based on the 16S rRNA gene sequence.Isolates No.Source of isolation (Locality of source)Isolation mediaClosest taxonClosest GeneBank relativeResponse to light^b^Genus/SpeciesOrderAccession No^a^Similarity (%)16Biotope (Kanagawa pref.)LB*Bacillus megateriumBacillales*AY03033899+199Paddy field (Ibaraki pref.)1/10 LB*Bacillus megaterium*EU88050699+295Forest soil (Kanagawa pref.)1/10 LB*Agromyces ulmiMicrococcales*AY42783098++2961/10 LB*Bacillus subtilisBacillales*FJ48351499++423Bran pickled (Kanagawa pref.)R2A*Brevibacterium linensMicrococcales*DQ36101698++459Snow (Yamanashi pref.)1/10 LBG*Sphingobacterium siyangenseSphingobacteriales*EU64627299++496Soil of residential land (Chiba pref.)1/10 LBG*Paeniglutamicibacter sulfureusMicrococcales*AB04635899++5041/10 LBG*Paeniglutamicibacter sulfureus*X8340999++5141/10 LBG*Paeniglutamicibacter sulfureus*EF15424599++5161/10 LBG*Microbacterium phyllosphaerae*AJ277840100+5261/10 LBG*Microbacterium foliorum*EU714341100+5271/10 LBG*Paeniglutamicibacter sulfureus*AB04635899++5501/10 LBG*Paeniglutamicibacter sulfureus*X8340999++647R2A*Paenibacillus alveiBacillales*AB37710899+732Biotope (Hokkaido)1/10 LB*Leifsonia shinshuensisMicrococcales*DQ23261499++742Paddy field (Ibaraki pref.)1/10 LB*Sinomonas atrocyanea*X8074699++905Cattle manure (Iwate pref.)1/10 LB*Glutamicibacter arilaitensis*EU83426099++9191/10 LB*Simplicispira metamorphaBurkholderiales*Y1861896+9431/10 LBG*Glutamicibacter nicotianaeMicrococcales*EU85742099++9511/10 LBG*Paenarthrobacter nicotinovorans*AB36393399+10311/10 LBG*Simplicispira metamorphaBurkholderiales*Y1861896+10391/10 LBG*Microbacterium natorienseMicrococcales*AY56629199++10521/10 LBG*Microbacterium natoriense*AY56629198++10771/10 LBG*Microbacterium natoriense*AY56629199++^a^Corresponding number in the nucleotide database of NCBI (<https://www.ncbi.nlm.nih.gov/nuccore/>).^b^+ and ++ indicate that carotenoid-like pigment production is

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the still, warm evening and sent so many leaves pattering down that we thought it was raining. We all held our breath, the other two appreciating the ecstasy of such a thing almost as you would.' In a subsequent letter to Greeves (18 October 1931) Lewis recounted the ideas proposed by Dyson and my father in respect of the 'true myth' of the story of Christ; and both in his _Biography_ and more fully in _The Inklings_ (Allen & Unwin, 1978, pp. 42-5) Humphrey Carpenter has imagined the discussion of that night, drawing from Lewis's letters and from the tenor of the argument of _Mythopoeia_. The second marginal note to the final text can be conveniently given here, though it is explanatory and does not bear on the history of the poem. The reference is to the eighth line of the ninth verse ( _bogus seduction of the twice-seduced_ ): ' _Twice-seduced_ , since to return to earthly well-being as a _sole_ end is one seduction, but even this end is mis-sought and depraved.' At the same time as these notes, my father wrote at the end of the manuscript: 'Written mainly in the Examination Schools during Invigilation.' The text of _Mythopoeia_ printed here is that of the final version exactly as it stands in the manuscript. Though the textual history is complex in detail, it can be said that the development of the poem through seven versions was largely a matter of extension. In the earlier forms it was much shorter, lacking the three verses beginning _Blessed are_ , and ending with the line _nor cast my own small golden sceptre down_. CHRISTOPHER TOLKIEN ## ON FAIRY-STORIES I propose to speak about fairy-stories, though I am aware that this is a rash adventure. Faërie is a perilous land, and in it are pitfalls for the unwary and dungeons for the overbold. And overbold I may be accounted, for though I have been a lover of fairy-stories since I learned to read, and have at times thought about them, I have not studied them professionally. I have been hardly more than a wandering explorer (or trespasser) in the land, full of wonder but not of information. The realm of fairy-story is wide and deep and high and filled with many things: all manner of beasts and birds are found there; shoreless seas and stars uncounted; beauty that is an enchantment, and an ever-present peril; both joy and sorrow as sharp as swords. In that realm a man may, perhaps, count himself fortunate to have wandered, but its very richness and strangeness tie the tongue of a traveller who would report them. And while he is there it is dangerous for him to ask too many questions, lest the gates should be shut and the keys be lost. There are, however, some questions that one who is to speak about fairy-stories must expect to answer, or attempt to answer, whatever the folk of Faërie may think of his impertinence. For instance: What are fairy-stories? What is their origin? What is the use of them? I will try to give answers to these questions, or such hints of answers to them as I have gleaned – primarily from the stories themselves, the few of all their multitude that I know. ## FAIRY-STORY What is a fairy-story? In this case you will turn to the _Oxford English Dictionary_ in vain. It contains no reference to the combination _fairy-story_ , and is unhelpful on the subject of _fairies_ generally. In the Supplement, _fairy-tale_ is recorded since the year 1750, and its leading sense is said to be ( _a_ ) a tale about fairies, or generally a fairy legend; with developed senses, ( _b_ ) an unreal or incredible story, and ( _c_ ) a falsehood. The last two senses would obviously make my topic hopelessly vast. But the first sense is too narrow. Not too narrow for an essay; it is wide enough for many books, but too narrow to cover actual usage. Especially so, if we accept the lexicographer's definition of _fairies_ : 'supernatural beings of diminutive size, in popular belief supposed to possess magical powers and to have great influence for good or evil over the affairs of man'. _Supernatural_ is a dangerous and difficult word in any of its senses, looser or stricter. But to fairies it can hardly be applied, unless _super_ is taken merely as a superlative prefix. For it is man who is, in contrast to fairies, supernatural (and often of diminutive stature); whereas they are natural, far more natural than he. Such is their doom. The road to fairyland is not the road to Heaven; nor even to Hell, I believe, though some have held that it may lead thither indirectly by the Devil's tithe. O see ye not yon narrow road So thick beset wi' thorns and briers? That is the path of Righteousness, Though after it but few inquires. And see ye not yon braid, braid road That lies across the lily leven? That is the path of Wickedness, Though some call it the Road to Heaven. And see ye not yon bonny road That winds about yon fernie brae? That is the road to fair Elfland, Where thou and I this night maun gae. As for _diminutive size_ : I do not deny that that notion is a leading one in modern use. I have often thought that it would be interesting to try to find out how that has come to be so; but my knowledge is not sufficient for a certain answer. Of old there were indeed some inhabitants of Faërie that were small (though hardly diminutive), but smallness was not characteristic of that people as a whole. The diminutive being, elf or fairy, is (I guess) in England largely a sophisticated product of literary fancy. It is perhaps not unnatural that in England, the land where the love of the delicate and fine has often reappeared in art, fancy should in this matter turn towards the dainty and diminutive, as in France it went to court and put on powder and diamonds. Yet I suspect that this flower-and-butterfly minuteness was also a product of 'rationalisation', which transformed the glamour of Elfland into mere finesse, and invisibility into a fragility that could hide in a cowslip or shrink behind a blade of grass. It seems to become fashionable soon after the great voyages had begun to make the world seem too narrow to hold both men and elves; when the magic land of Hy Breasail in the West had become the mere Brazils, the land of red-dye-wood. In any case it was largely a literary business in which William Shakespeare and Michael Drayton played a part. Drayton's _Nymphidia_ is one ancestor of that long line of flower-fairies and fluttering sprites with antennae that I so disliked as a child, and which my children in their turn detested. Andrew Lang had similar feelings. In the preface to the _Lilac Fairy Book_ he refers to the tales of tiresome contemporary authors: 'they always begin with a little boy or girl who goes out and meets the fairies of polyanthuses and gardenias and appleblossom... These fairies try to be funny and fail; or they try to preach and succeed.' But the business began, as I have said, long before the nineteenth century, and long ago achieved tiresomeness, certainly the tiresomeness of trying to be funny and failing. Drayton's _Nymphidia_ is, considered as a fairy-story (a story about fairies), one of the worst ever written. The palace of Oberon has walls of spider's legs, And windows of the eyes of cats, And for the roof, instead of slats, Is covered with the wings of bats. The knight Pigwiggen rides on a frisky earwig, and sends his love, Queen Mab, a bracelet of emmets' eyes, making an assignation in a cowslip-flower. But the tale that is told amid all this prettiness is a dull story of intrigue and sly go-betweens; the gallant knight and angry husband fall into the mire, and their wrath is stilled by a draught of the waters of Lethe. It would have been better if Lethe had swallowed the whole affair. Oberon, Mab, and Pigwiggen may be diminutive elves or fairies, as Arthur, Guinevere, and Lancelot are not; but the good and evil story of Arthur's court is a 'fairy-story' rather than this tale of Oberon. _Fairy_ , as a noun more or less equivalent to _elf_ , is a relatively modern word, hardly used until the Tudor period. The first quotation in the _Oxford Dictionary_ (the only one before AD 1450) is significant. It is taken from the poet Gower: _as he were a faierie_. But this Gower did not

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, with every hair in place! Because of this Aron has hundreds of satisfied clients. Many of which return years later for a portrait of the next generation of their pets. Your picture will be on your wall for many years, so it pays to ensure it is a fitting reminder of your animal. In fact some families club together to commission a pet portrait for a special birthday or anniversary. For more information about Aron's pet portraits please click on the Artist button, or to see more examples of previous commissions, enter the galleries by clicking on one of the gallery buttons above. Aron provides a complete pet portrait service, from photo-shoot to framing, and although based in Andover, Hampshire, (which is near the borders of Berkshire and Wiltshire,) routinely receives commissions for his animal portraits from all over the South of England, especially Sussex and Surrey. He also travels to Yorkshire a couple of times a year and can do photoshoots anywhere in-between. In this way he can cover most parts of the UK.Welcome to the PokéCommunity! Hi there! Thanks for visiting PokéCommunity. We’re a group of Pokémon fans dedicated to providing the best place on the Internet for discussing ideas and sharing fan-made content. Welcome! We’re glad you’re here. In order to join our community we need you to create an account with us. Doing so will allow you to make posts, submit and view fan art and fan fiction, download fan-made games, and much more. It’s quick and easy; just click here and follow the instructions. Pokémon Sun and Moon are now available! Read our extensive Sun and Moon review at Daily! The finale of the fourth annual Favorite Pokémon Tournament is underway in Pokémon General!View the poll and vote for as many Pokémon as you'd like. Voting is only open until the 5th of December though, so don't wait to make your picks! I've never been in a relationship like the one you're in now, and I won't pretend and say I know how you feel, cause I don't. I just don't want to see you get hurt. Every time I see you come run to me and cry over the past mistakes your boyfriend made, it makes me feel so sorry for you. But you have to realize that at this point, it's your stubbornness that's making your life a living hell. He changed for the better. Sure, it took a few mistakes, but you say that he did, and I believe that. I only met the dude once, but he seems alright. To be so caught up in the past, though, isn't healthy. I told you that at this point you had two options, either forget the past, or break up with him. The way I see it, it doesn't matter how much you love him, if being with him hurts you so much (cause this has been happening for a while now) then it just isn't worth it. And yeah, I know it's easier said than done. But like I said, I don't want to see you get hurt. Please, for your sake, do something. You used to be a really great friend until you started acting all weird and drifted off. You ignoring me got on my nerves to the point where I started ignoring you too. I'm already trying my best to patch things up so I do hope you are putting in some effort too! I hope all goes well soon. I miss you, my friend. I've been meaning to text you and ask if we could chill anytime soon, especially since you live up the road from me. We both said to each other that we should hang over the summer before we graduated, but we have yet to do that. It's been a month since I've seen you, so please at least remember who I am if I text you and ask you if we could hang in the near future. Thank you so much for the times we had together but I wish you would come home. I know that you have a life now and your priorities are first, but I havent seen you in months and just I want to know that our graduation wasnt the last time I'll ever get to see you. Please visit me soon dude. Oh god, you're making things so awkward. I don't know if your texts are unintentionally making me feel uncomfortable, or if you're slyly making me feel guilty over what I did. If it's the latter, you're doing a good job. I said I couldn't do it, and I had my reasons. I said I'm sorry. What more do you want from me? I was scared to message you at first about this, but I'm thankful now that we will be seeing each other again soon. I can't wait for you to come over and hang out with me for a few hours. See you soon! You should learn to follow your own advice. It's getting a little tiresome. da, It was nice seeing you after you came to the city. I'm even surprised that you picked me out of every other person there. Hopefully you come back here soon, and perhaps we can take a day to hang out, or perhaps I can give you my number so we can text each other. da, I really miss you and I want to text you again. I can't wait for August. Get back sooner. da, I think you're really cute, but I don't think we could hit it off in a million years. The end of July is coming, regardless of how slow it is. When you come up, we have to make as much of the time as we can get. Because who knows when you'll be up after that. We do have skype, but I'd rather actually hang out with someone rather than talk with them on a screen for 25 or 30 minutes. Things really didn't go as how I expected it. The first day of school it was okay and you were really friendly and I liked that. But the very next day you started it all over again. You used my stationery, drew on my papers and invaded a large portion of my table space, all without asking. Really, I would have let you do so if you just asked. Don't just assume that I'm fine with everything because I don't seem to show any disapproval. I have feelings too. And the only reason I don't stop you from doing all these is because it isn't in my character to do so and I'd probably hurt your feelings if I told you. I do know that you're feeling very lonely in class despite being surrounded by so many classmates I can't help you if this continues. I sincerely hope things head towards the better. And like what the teacher told us, 'Our feelings can connect with the heart but the mind has to work on it's own to set things right', or in other words, think before you act based on your emotions. I'll be trying my best to do this so let's work hard together! So I have a lot of wasted intellect and a lot of spare time on my hands, I can assure you they were entirely coincidental and I want to apologise if I made you uncomfortable or offended you in any way. I'll drop it when you drop it. Dear Anonymous, I seemed to have forgotten about you for a while but here you are again. Back in my news feed. I always did think you were cute, ever since E was stalking your photos and I was silently observing. You have no idea how cranky she got afterwards, so jealous. I know we've never met in person but I really want to get to know you, both E and D tell me about how kind and fun you are. I can't just say hi over the internet because we both know that any chump with a keyboard can do that, I want to do it right, besides I've tried that before and nothing comes of it. I know your time being single is running out, we should be introduced. It could be good. I am so glad you are doing better this week as I know last week was a mess for all of us D:. I thought when you were having thoughts of giving up, I'd lose another person close to me, but with you now looking at the bright side of the future everything seems good and well. You are such a bad influence, but I love you <3 I wish we were still friends, but we have grown and moved a part. I still like hearing the stories about how bad you truly are, even though I know you mean well. Talking about anime like nothing happened isn't really doing me any favors. I know you know that. I'm sorry I'm a pain in the ass to deal with but I can't help it. Please just understand. Leave me alone for awhile... but, then again, I don't think I can stand to not talk to you any more than I already have. I miss you more and more each day. I know you're having a fun time, but I... I just miss what we used to be. I can't wish you back any more, because it'll just be wasted effort. It's not your fault; it's mine. I just wish I could've been a better boyfriend. I'm sorry. Dear anonymous... I'm sorry. I really don't want to mess anything up with your new love, but... just remember I'm still here, okay? I don't see what's the big deal with me doing events on forums. Really have you never

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weak Outcome statements, with suggestions on how they can be improved. Examples of strong and weak Outcome statements Results Reporting Format The Guide provides a useful new format for results reporting. In the past different projects have reported in a wide variety of ways, often forcing readers to wade through dozens of pages of descriptions of activities, in a vain attempt to find out what the results are. This suggested new format puts results up front, in a table, emphasizing indicator data, with room for explanations in text, below. These and other additional tips can be found in section 3 – Step by Step Instructions on results-based project planning and design (p. 66-85) and section 4 – Managing for Results during Implementation (p. 86-92) but others are spread throughout the document, and for that reason it is useful to read the whole document, even if users are familiar with past CIDA/GAC documents. Limitations This is a good, practical RBM guide, but having a good guide is one thing, and getting people to use it – or to deal with the implications of what it means for agency operation, is another. I see two areas where further improvements could be made, some of which could be done informally, and some which, given procedures in the Government of Canada, are perhaps beyond the scope of the GAC RBM group’s control. 1. Dealing with the Implications of RBM for operations and funding I have seen very small civil society organizations face lengthy processes of data collection and report revisions, to comply with donor agency RBM requirements for relatively inexpensive projects. But at the same time donor agencies themselves - and this means most donors - often do not deal realistically with the implications of their own guidelines for project budgets. Baseline data Take baseline data collection, for example. The GAC Guide sections on Indicators and the Performance Measurement Framework (p. 52-64) are generally quite practical, and make the very valid point that baseline data for indicators must be collected before targets can be established, and results reported on. I agree completely that this is the most useful way to proceed – if the time and budget are allocated to make it possible. As the GAC guide says about baseline data (I have added emphasis): "When should it be collected? Baseline data should be collected before project implementation. Ideally, this would be undertaken during project design. However, if this is not possible, baseline data must be collected as part of the inception stage of project implementationin order to ensure that the data collected corresponds to the situation at the start of the project, not later. The inception stage is the period immediately following the signature of the agreement, and before the submission of the Project Implementation Plan (or equivalent). "[p. 60] In a rational process this would in fact be the situation. But the reality is that for projects funded by GAC and many other donors, after two or three years of project design and approval processes, both the donor and the partners in the field want to start actual operations quickly. The amount of time allocated by donors and partners for the inception field trips by implementing agencies – and the budget allocated to support baseline data collection processes - are too limited to make baseline data collection for all indicators during the inception period feasible in all but the most unusual cases. A typical inception field trip for an inception period might last 3-4 weeks, rarely longer, and during this period a theory of change process has to be initiated with all of the major stakeholders, an existing logic model tested and perhaps revised, a detailed work breakdown structure, and risk framework developed, institutional cooperation agreements negotiated, and detailed discussions on a Performance Measurement Framework with a multitude of potential stakeholders completed. As the GAC guide notes: "As with the logic model, the performance measurement framework should be developed and/or assessed in a participatory fashion with the inclusion of local partners, intermediaries, beneficiaries and other stakeholders, and relevant Global Affairs Canada staff." [p. 58] Some of these indicator discussions alone, where an initial orientation is required, and where there are multiple stakeholders, with different perspectives and different areas of expertise involved, can take 20 or 30 professional staff one or even two weeks in full time sessions, to reach initial agreement on what are sometimes 30 or 40 indicators. In some cases baseline data are available immediately, and that is one important criterion in choosing between what may be equally valid indicators. But in many cases, the data collection must be assigned to the partner agencies in the field, who know where the information is, and how to get it. All of this means that a second round of discussions must be undertaken, to discard those indicators for which baseline data are unavailable, or just too difficult to collect and agree on new indicators. And, as the GAC guide quite correctly notes: "The process of identifying and formulating indicators may lead you to adjust your outcome and output statements. Ensure any changes made to these statements in the performance measurement framework are reflected in the logic model." [p. 81] The partners, meanwhile, have their existing work to continue with – and rarely see the baseline data collection as their most important operational priority given the political and institutional realities they fact to do their normal work. I have participated in several design and inception missions, and I cannot remember when baseline data for all indicators were actually collected before the project commenced. And at mid-term in many projects it is not unusual for an audit of the indicators by a monitor to find that 30-40% of the indicators may not have baseline data, even after two or three years of project operation. All of this could be avoided if more money and more time – up to six months perhaps – were allocated to the inception period, with an emphasis on establishing a workable monitoring and evaluation structure, and actually funding baseline data collection. That means that when a donor agency emphasizes participatory development of indicators, during an inception period, it should be prepared to provide the resources of time and money necessary to make this practical. 2. Limiting the Logic Model to three levels The GAC logic model has three results levels - for short-term, medium term and very long term changes. This is about standard for most agencies. But, of course, only two of these levels are actually operational, and susceptible to direct intervention during the life of the project – Immediate Outcomes in the short term (1-3 years on a 5 year project) and Intermediate Outcomes which should be achieved by the end of the project. The Ultimate Outcome level is the result to which the project, along with a host of other external agencies, including the national government, and other donors, may be contributing. In real life, a Logic Model which actually reflects the series of interventions, from changes in understanding, which are necessary for a change in attitudes, to changes in decisions or policies and changes in behaviour or professional practice, will go through a minimum of 4 to 5 or even more stages where needs assessments, and training of trainers or researchers lie at the beginning of the process, before we get to field implementation of new policies or innovations. I have worked with partners in the field during project design where during the theory of change analysis, up to 8 different levels were identified, with assumptions, interventions and purported cause and effect links between these levels, before ever getting to the ultimate long-term result. It is impractical, the donors would argue, to have even a 5 level Logic Model – and this would indeed require extra work on indicators. But while the Global Affairs RBM guide does give a nod, on page 48, to the idea of “nested logic models” something I have worked on with partners, these can be more complicated to present and to understand than a 4 or 5-layer Logic Model. Some partners have decided to maintain their own more detailed, multi-level logic models, and present a simplified version to the donors, because the whole purpose of these tools is not primarily for reporting to donors – but to help managers determine what interventions are working, and what changes are needed. That is why the process is called Results-Based Management, and not just results based reporting. Having produced a more detailed and informal Logic Model, these partners, when an evaluator, a Minister, or a new donor representative has difficulty seeing how a simple two layer Logic Model can actually attribute results to interventions, can produce the real Logic Model and explain the relationships. It is unlikely that any donor will agree to a 4 or 5-level Logic Model, but it would be useful, as this Guide will be revised, to include a section illustrating the process of nesting Logic Models. The Bottom Line This new Global Affairs Canada Results-Based Management guide is an absolutely necessary tool and reference for anyone working on Canadian aid projects – and it is a practical, very useful resource for anyone who wants clarity on the process of results-based project design. I will keep the old 2001 PIP Guide on hand, however, for its still useful detail, and user-friendly format, as a complement to the new RBM guide. Greg Armstrong is a Results-Based Management specialist who focuses on the use of clear language in RBM training, and in the creation of usable planning, monitoring and reporting frameworks. For links to more Results-Based Management Handbooks and Guides, go to the RBM Training website. About Me Greg Armstrong brings what we know about how adults learn to helping international development workers use Results-Based Management in their work. If it is done right, it can be enjoyable, and productive, helping us explain our work to others.Yeah. the current story does NOT have the characters merrily sitting around their kitchen table... i know... I drew this 2 months ago to have a short to get people into twistEd. The goal was to have a short comic in

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gets expensive very quickly just from the standpoint of shipping and insurance. It never hurts, though, to call the nearest Canon service center and get an estimate. Also check with your courier of choice to see how much it will cost to ship and insure your camera to the service center. Although Canon does not officially consider the focus screen of the Rebel T3i/600D user replaceable, the method to remove/replace the focusing screen is very similar to models that are considered as such by Canon. If you choose to try it yourself please do so at your own risk! You must accept full responsibility for whatever happens to your camera. We accept no liability for any damage resulting from your choice to use the instructions linked below. Should damage occur as a result of following these instructions you accept full responsibility for the cost of any servicing, repair, or correction needed. Here are the instructions from katzeye optics for removing/replacing the focusing screen of the 600D. Please also be aware that even after successfully removing the focusing screen, it may or may not be possible to clean the residue of the dead bug from the screen without damaging the delicate surface of the screen. Some Canon camera models do have focusing screens officially considered user replaceable while others do not. Many of the higher end models that do not support user replaceable focusing screens include LCD overlays for displaying information in the viewfinder. The early models with the LCD overlays (7D, 5D Mark III, 70D) do not support user replaceable focusing screens. Due to the presence of the LCD overlay the removal/replacement of a focusing screen on those models is even more involved and delicate that that of your 600D. The newer 7D Mark II and 6D include an LCD overlay but also have focusing screens considered user replaceable and several alternate focusing screen options are available from Canon. None of the Rebel/xx0D/xxx0D series or the x0D series prior to the 50D officially support user replaceable screens either. Some of the newer models in those series may also include an LCD overlay. Here's a list from Canon as of 11/04/2015 that includes which cameras have officially user replaceable focusing screens and which replacement screens are compatible with which models. (The newest Canon models, the EOS 5Ds and EOS 5Ds R, are not listed on the 11/04/2015 version of the list) https://support.usa.canon.com/kb/index?page=content&id=ART143832 Contact Us For Customer Support Direct mail correspondence to: Your Hospital Bill It is important to remember that your hospital bill covers services provided by the hospital: room, nursing care, meals, housekeeping and linen. It may also include services ordered by your physician: X-rays, laboratory tests, medical supplies and oxygen. The bill does not include charges for your personal physician, surgeon, anesthesiologist, pathologist, emergency physician, radiologist, or other physician assistants. You will receive separate bills from these physicians.(RTL::BVECP) (RTL::FL) (RTL::BITS) (RTL::BITN) (RTL::MULCAT (5 5 (:TYPE-PRESCRIPTION RTL::NONNEG-+-TYPE))) (RTL::MULCAT-NONNEGATIVE-INTEGER-TYPE) (RTL::MULCAT-1 (632 11 (:REWRITE RTL::BITS-SPLIT-AROUND-ZERO)) (285 19 (:REWRITE RTL::BVECP-WITH-N-NOT-A-POSITIVE-INTEGER)) (250 25 (:LINEAR RTL::EXPT-WITH-SMALL-N)) (224 11 (:REWRITE RTL::BITS-TAIL)) (209 11 (:REWRITE RTL::BITS-WITH-INDICES-IN-THE-WRONG-ORDER)) (187 122 (:REWRITE DEFAULT-<-2)) (148 122 (:REWRITE DEFAULT-<-1)) (139 139 (:REWRITE RTL::NON-INTEGERP-<-INTEGERP)) (139 139 (:REWRITE RTL::LESS-THAN-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-RIGHT-HAND-SIDE)) (139 139 (:REWRITE RTL::LESS-THAN-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-LEFT-HAND-SIDE)) (139 139 (:REWRITE RTL::INTEGERP-<-NON-INTEGERP)) (139 139 (:REWRITE RTL::EXPT-COMPARE)) (139 139 (:REWRITE RTL::CANCEL-COMMON-FACTORS-IN-<)) (122 122 (:META CANCEL_PLUS-LESSP-CORRECT)) (115 6 (:LINEAR RTL::BITS-LESS-THAN-X-GEN)) (114 91 (:REWRITE DEFAULT-+-1)) (112 6 (:LINEAR RTL::BITS-LESS-THAN-X)) (110 11 (:REWRITE RTL::BITS-FORCE-WITH-A-CHOSEN-NEG)) (103 91 (:REWRITE DEFAULT-+-2)) (99 33 (:TYPE-PRESCRIPTION RTL::INTEGERP-PROD)) (66 66 (:REWRITE RTL::EXPT-WITH-I-NON-INTEGER)) (66 66 (:REWRITE RTL::EXPT-EXECUTE-REWRITE)) (66 66 (:REWRITE RTL::EXPT-2-EVALUATOR)) (55 11 (:REWRITE A2)) (50 50 (:LINEAR RTL::EXPT-EXCEEDS-2)) (36 18 (:REWRITE RTL::BITS-WITH-I-NOT-AN-INTEGER-2)) (35 13 (:REWRITE DEFAULT-*-2)) (29 29 (:TYPE-PRESCRIPTION RTL::EXPT-2-POSITIVE-INTEGER-TYPE)) (26 26 (:REWRITE RATIONALP-IMPLIES-ACL2-NUMBERP)) (22 11 (:REWRITE RTL::BITS-WITH-I-NOT-AN-INTEGER)) (19 19 (:REWRITE RTL::BVECP-LONGER)) (18 18 (:REWRITE RTL::BITS-WITH-J-NOT-AN-INTEGER-2)) (18 18 (:REWRITE RTL::BITS-EXPT-CONSTANT)) (13 13 (:REWRITE DEFAULT-*-1)) (11 11 (:REWRITE RTL::BITS-WITH-X-NOT-RATIONAL)) (11 11 (:REWRITE RTL::BITS-WITH-J-NOT-AN-INTEGER)) (11 11 (:REWRITE RTL::BITS-WITH-BAD-INDEX-2)) (11 11 (:REWRITE RTL::BITS-IGNORE-NEGATIVE-BITS-OF-INTEGER)) (8 8 (:REWRITE RTL::POWER2-INTEGER)) (8 8 (:REWRITE RTL::INTEGERP-MINUS)) (6 6 (:REWRITE RTL::NONNEG-+)) (6 2 (:REWRITE RTL::BVECP-OF-NON-INTEGER)) (3 1 (:REWRITE RTL::INTEGERP-IMPLIES-NOT-COMPLEX-RATIONALP)) (2 2 (:REWRITE RTL::CAT-WITH-N-NOT-A-NATURAL)) (2 2 (:REWRITE RTL::CAT-WITH-M-NOT-A-NATURAL)) (2 2 (:REWRITE RTL::CAT-TIGHTEN-X)) (1 1 (:REWRITE RTL::EXPT-COMPARE-EQUAL)) (1 1 (:REWRITE RTL::EQUAL-OF-PREDS-REWRITE)) (1 1 (:REWRITE RTL::EQUAL-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-RIGHT-HAND-SIDE)) (1 1 (:REWRITE RTL::EQUAL-MULTIPLY-THROUGH-BY-INVERTED-FACTOR-FROM-LEFT-HAND-SIDE)) (1 1 (:REWRITE RTL::CANCEL-COMMON-FACTORS-IN-EQUAL)) (1 1 (:REWRITE RTL::BITS-MATCH)) (1 1 (:REWRITE RTL::BITS-EQUAL-IMPOSSIBLE-CONSTANT)) (1 1 (:REWRITE RTL::BITS-DONT-MATCH)) (1 1 (:META CANCEL_TIMES-EQUAL-CORRECT)) (1 1 (:META CANCEL_PLUS-EQUAL-CORRECT))) (RTL::MULCAT-BVECP-SIMPLE (470 4 (:REWRITE RTL::CAT-WITH-M-NOT-A-NATURAL)) (352 5 (:REWRITE RTL::REARRANGE-NEGATIVE-COEFS-<)) (245 4

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worst of cruelties? Helen had said that the boy-men who had tortured her sister _wanted_ to be what they thought of as beasts. They turned toward the dark and the base, I realized, because they feared the glorious and the high. In truth, they dreaded with a gut-fluttering, heart-crushing terror becoming the bright songs of the earth that they most longed to sing. So it was with me. This new knowledge of myself afflicted me, and I could scarcely bear it, for I had conceived myself almost entirely otherwise. What did I most dread, I wondered? What song did I long to sing? How badly I wished to ask these questions of my grandmother and my mother, to speak and swim once more with my first family whom I had nearly forgotten in my joy of dwelling with Zavijah, Salm, and all my new sisters and brothers who had been slaughtered! Unukalhai, Alkurah, Kitalpha, and Hyadum, too, were gone, lost into the gray-blue deeps of the northern ocean. A single orca remained with whom I might share the wonderings that tormented me. How, though, could I speak of such things with a whale as young as Baby Electra? How could I add to her own torment, which she could scarcely bear? 'It hurts so bad!' she moaned out to me as we swam side by side through the sting of the salty sea. 'There is a hole in me, Arjuna!' She spoke not of the bloody wound that the man's grenade had torn out of her side, but the much deeper loss of whales she had loved. It shocked me that she included me in her remembrance of the murdered, for with an amazing percipience and compassion in one so young, she understood that the violence I had inflicted upon the man had destroyed something precious in me. 'Please do not leave me,' she said as she limped alongside me. 'I never would! I will swim with you until the end of—' 'Please do not leave me in your heart. I cannot live without _you_.' I swam on in silence for a while. Then I tried to divert the stream of her thoughts. 'I should have known that the humans would not want to hear what I had to say,' I told her. 'If I had not opened my big mouth...' 'But what does your mouth have to do with making sounds?' 'It is a figure of speech you never learned.' 'I feel that I learned so much from the humans – and so little.' We moved through the dark gray water, zanging frequently to see what lay ahead of us – and behind. 'All things have a soul,' Baby Electra continued. 'The minnows, the crabs, the starfish, the diatoms – all these beings and so with even the seaweed and the rocks of the green-shrouded shore. But how can it be, Arjuna, that the humans have a soul?' She spoke hyperbolically and too passionately for one so grievously wounded, but she spoke to a point. I said to her: 'What of Gabi, then? What of Helen?' 'They are the exceptions that prove the rule,' she said. 'I sometimes think that Descartes was correct in characterizing animals as soulless automatons, if by animals is meant human beings.' 'You know that humans are not automatons.' 'No, they are something much worse,' she said. 'Any part of reality that vexes them they destroy with a will and a glee. Why have our kind made a covenant with such creatures?' 'I do not know.' 'But you _must_ know! You are an adult, Arjuna.' 'I have not completed my rhapsody. Perhaps I never will.' 'You will! You will! And you will speak to the adults of the things that adults speak of.' 'Once,' I said, 'I overheard my grandmother and mother discussing the Great Covenant.' 'And what did they say?' 'Little that made sense to me. My grandmother said that the Great Covenant is a mystery that may not be questioned.' 'But we orcas question everything!' 'Of course we do. That is what makes my grandmother's pronouncement so mysterious.' 'Perhaps in our questioning, we should question that we question everything.' 'Of course, that is also true. I am glad that you have not allowed your wound to divert you from thought play.' 'I want to live! I want to know... so much!' 'I am glad,' I said to her as we glided beneath the waves above us. 'If we may not question the _why_ of the Great Covenant,' she said, 'may we not wonder about the _where_ and the _how_? From where did it come? How has it been passed down to our kind for so many ages?' 'Only the deep gods,' I said, 'know this. It is said that they persuaded the Old Ones to make covenant with the humans long ago.' 'But orcas do not speak with the deep gods!' 'Once we did,' I told her. 'I wish _I_ could speak with them.' 'And what would you say?' She thought about this as she swam. She winced at the pain that shot through her with every movement of flipper and fluke. 'I would say this,' she told me. 'I have chosen to question the Great Covenant after all. What can be made can be unmade, yes? Perhaps the time has come to bury the Great Covenant in the place we left Bellatrix's and Menkalinan's bodies.' Her voice spread out into the much deeper plaint and moaning of the sea. The waves carried to us the thunder of faraway storms and the much nearer booming of each other's heart. We both listened again and again to the death cries of Zavijah and her sister, and I could not help hearing anew the murdered man's shrieks. The deeps concealed even more disturbing stridencies that we felt touching our bones. All this clamor tinged the water with argrege and inkvol. We swam through these darker colors of sound in remembrance of brighter days. 'I am cold,' Baby Electra said to me as fever set in. She pressed up against me as we swam slowly toward the west. 'Stay close to me, Arjuna.' I pressed my side to her burning flesh. I wished I could soften my skin and remove it so that I might drape it like a cloak over her trembling body. 'I am hungry, too,' she said. So was I. It had been long days and nights of swimming through sunlit and moonshadowed seas since we had eaten. I zanged the restless green waters about us, but only a couple of fish did I detect. 'Where are all the salmon?' she asked. 'The humans have ravished this place. They are like sharks.' I held my breath as I counted my heartbeats, giving up when I reached twenty-three. I aimed zangs of sonar to the west, south, east, and north – and then up and down. What dwelled in the black and whisperless deeps, I wondered, which no orca had ever dared to fathom? 'The humans are _worse_ than sharks,' she added. 'Sharks eat only when they are hungry, but the humans eat just because they like to eat.' 'I have been thinking about sharks myself,' I told her. 'Have you then zanged the two that are following us?' 'Of course I have.' 'Then why did you wait for me to speak of them?' 'I had thought that the pain of your body,' I said, 'would be enough for you to endure.' 'What kind of sharks do you think they are?' Only one kind of shark swam so steadily through such cold water in pursuit of wounded whales. We knew of these sharks as the Magnificent Ones while the humans called them the Great Whites. I told this to Baby Electra, and she seemed to press herself through my side into my clenching belly. 'I have little experience of the Magnificent Ones,' she said. 'If any had thought to come near my family, Pherkad and my mother – Asteropei, too! – would have killed them quickly.' 'If these two come close to you,' I said to her, 'I will kill them, though it might not be quickly.' 'Have you killed such sharks before?' Only in my dreams, I thought. Only in my nightmares. 'No, I have not,' I said. 'But I know how to. My grandmother once instructed me.' 'I do not want you to kill them,' she said. 'What if they wound you as I am wounded? Who would protect me?' 'Let us keep moving,' I said. 'Perhaps they will lose interest in us.' We swam as quickly as Baby Electra could manage toward that red, glowing place where the sun disappears each night

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FN~2~O~10~ Formula weight 400.42 459.95 429.93 626.62 Temperature 293(2) 293(2) 293(2) 293(2) Wavelength (Å) 0.71073 0.71073 0.71073 0.71073 Crystal system Triclinic Triclinic Orthorhombic Monoclinic Space group P-1 P-1 Pbca P2~1~ *a* (Å) 9.3040(19) 6.0180(12) 13.698(3) 11.838(2) *b* (Å) 10.507(2) 8.2370(16) 7.6260(15) 9.4500(19) *c* (Å) 12.075(2) 21.600(4) 38.908(8) 14.514(3) *α* (°) 68.70(3) 87.08(3) 90.00 90.00 *β* (°) 81.40(3) 87.46(3) 90.00 100.41(3) *γ* (°) 67.99(3) 82.30(3) 90.00 90.00 Volume (Å^3^) 1,019.5(4) 1,058.9(4) 4,064.4(14) 1,596.9(6) *Z* 2 2 8 2 Calculated density (Mg/m^3^) 1.304 1.443 1.405 1.303 Absorption coefficient (mm^−1^) 0.090 0.406 0.414 0.101 *F*(000) 420 476 1,776 660 Crystal size (mm) 0.10 × 0.20 × 0.30 0.05 × 0.05 × 0.10 0.10 × 0.20 × 0.30 0.10 × 0.20 × 0.30 *θ* range for data collection(°) 1.81--25.36 1.89--25.28 1.05--25.28 1.43--25.25 Index ranges 0 ≤ h ≤ 11\ 0 ≤ h ≤ 7\ 0 ≤ h ≤ 16\ −14 ≤ h ≤ 13\ −11 ≤ k ≤ 12\ −9\ 0 ≤ k ≤ 9\ 0 ≤ k ≤ 11\ −14 ≤ l ≤ 14 ≤ k ≤ 9 −25 ≤ l ≤ 25 0 ≤ l ≤ 46 0 ≤ l ≤ 17 Reflections collected 4002 4239 3688 3091 Independent reflections \[*R*(int)\] 3750 \[*R*(int) = 0.045\] 3843 \[*R*(int) = 0.061\] 3688 \[*R*(int) = 0.034\] 3091 \[*R*(int) = 0.052\] Max. and min. transmission 0.9911 and 0.9736 0.9800 and 0.9605 0.9597 and 0.8857 0.9900 and 0.9704 Refinement method on *F*^2^ Full-matrix least-squares Full-matrix least-squares Full-matrix least-squares Full-matrix least-squares Data/restraints/parameters 3750/0/271 3843/0/272 3688/0/253 3091/7/388 Goodness-of-fit on *F*^2^ 1.005 1.002 1.032 1.004 Final *R* indices \[*I* \> 2*σ*(*I*)\]; *R*~1~, *wR*~2~ *R*~1~ = 0.0688\ *R*~1~ = 0.0854\ *R*~1~ = 0.0740\ *R*~1~ = 0.0656\ *wR*~2~ = 0.1508 *wR*~2~ = 0.1592 *wR*~2~ = 0.1616 *wR*~2~ = 0.1567 *R*~1~, *wR*~2~ (all data) *R*~1~ = 0.1452\ *R*~1~ = 0.1766\ *R*~1~ = 0.1359\ *R*~1~ = 0.1000\ *wR*~2~ = 0.1835 *wR*~2~ = 0.1897 *wR*~2~ = 0.1922 *wR*~2~ = 0.1798 Largest diff. peak and hole (e·Å^−3^) 0.149 and −0.169 0.451 and −0.266 0.325 and −0.358 0.226 and −0.577 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------- molecules-19-01302-t002_Table 2 ###### Selected bond lengths (Å), bond angles/torsion angles (°) for **I**, **II**, **III**, and **IV**. Comp. Bond lengths (Å) X-ray Bond angles/Torsion angles (°) X-ray --------- ------------------ ---------------- -------------------------------- ---------- **I** C11-O3 1.391(4) C9-C10-C11 104.2(3) N1-N2 1.374(3) N2-N1-C11-O3 173.5(3) C5-C9 1.472(4) N1-N2-C9-C5 −172.8(3) O3-C18 1.360(4) C1-O1-C8-C7 5.0(5) C2-O2-C3-C4 −2.7(5) **II** C6-O2 1.326(8) C6-C7-C8 106.3(5) N1-C4 1.417(7) N3-N2-C6-O2 −179.7(6) C7-Cl 1.732(6) N2-N3-C8-C9 −176.1(6) N2-N3 1.357(6) C15-O3-C12-C11 1.1(11) C8-C9 1.479(8) C4-N1-C3-S2 −1.0(10) O2-C5 1.414(7) **III** C15-O1 1.351(5) C13-C14-C15 104.9(4) N3-C17 1.412(6) N1-N2-C15-O1 178.1(4) C11-Cl 1.730(7) N2-N1-C13-C7 177.8(4) N1-N2 1.365(5) C17-N3-C18-S1 9.4(7) C7-C13 1.477(7) O1-C16 1.424(5) **IV** C10-O1 1.392(6) C10-C11-C12 104.4(5) C16-F 1.380(7) N2-N1-C10-O1 177.4(6) N1-N2 1.388(5) N1-N2-C12-C13 −176.3(6) C12-C13 1.499(7) O1-C19-O2-C20 −173.8(4) O1-C19 1.404(6) O2-C19-C23-O10 −174.2(4) C21-C20-C26-O4 −61.0(6)

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1142, 2069, 858, 368, 5731, 352, 32, 49108, 310, 247, 747, 6907, 273, 294, 14, 30767, 1232, 15, 187, 187, 2598, 2080, 359, 897, 581, 4451, 21674, 323, 4095, 13, 533, 326, 310, 417, 2217, 281, 10517, 776, 2852, 3198, 1905, 7895, 3708, 285, 6032, 1048, 1307, 10393, 15, 187, 187, 30882, 273, 19348, 313, 1838, 80, 53, 10, 588, 2489, 247, 747, 2629, 15, 380, 1953, 310, 672, 352, 588, 5108, 15, 1916, 1918, 368, 271, 2934, 13, 359, 878, 281, 2794, 37377, 342, 690, 2173, 12474, 13, 824, 347, 27, 187, 187, 10002, 18461, 352, 187, 187, 9453, 352, 369, 18329, 187, 187, 5371, 310, 253, 3264, 1495, 673, 5880, 187, 187, 10002, 21186, 352, 187, 187, 5371, 941, 310, 352, 16778, 187, 187, 2214, 12861, 4685, 309, 5583, 368, 281, 1239, 309, 37326, 2440, 3971, 4251, 15, 187, 187, 510, 5962, 448, 267, 4703, 323, 5948, 374, 15, 17, 187, 187, 3378, 5675, 1180, 273, 7060, 4095, 13, 627, 588, 320, 625, 941, 7137, 15, 5128, 2097, 4151, 569, 285, 4151, 569, 403, 2583, 313, 263, 1612, 13, 604, 368, 4510, 481, 1876, 253, 37377, 313, 38340, 38, 10, 5511, 1364, 320, 28454, 15, 2596, 273, 253, 309, 37326, 13157, 310, 1925, 36685, 264, 5271, 7737, 456, 15551, 2977, 285, 697, 2628, 310, 281, 7895, 285, 42347, 2862, 941, 5542, 15, 7214, 14047, 4676, 588, 320, 2104, 281, 1239, 285, 17029, 253, 5542, 15, 3035, 22243, 272, 253, 941, 18361, 310, 253, 2644, 2170, 326, 3198, 281, 320, 3715, 342, 247, 747, 1039, 273, 2746, 15, 187, 187, 24234, 407, 954, 1774, 310, 3988, 15, 1284, 776, 5948, 1732, 11220, 1756, 13, 359, 3395, 3469, 386, 327, 3694, 285, 10309, 15, 844, 2489, 625, 14043, 281, 3694, 390, 10309, 43280, 390, 48109, 434, 8104, 15, 380, 2852, 588, 1379, 1659, 1014, 625, 275, 2645, 1653, 4511, 13, 594, 3988, 943, 320, 776, 806, 11674, 672, 359, 26400, 323, 247, 13817, 1818, 15, 187, 187, 42175, 13782, 285, 17823, 2847, 37403, 281, 3988, 19414, 13, 984, 275, 253, 3551, 8007, 359, 476, 923, 1077, 1524, 6387, 273, 44755, 6318, 12823, 15, 831, 588, 13201, 954, 273, 10105, 5576, 14238, 908, 3063, 15, 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285, 40880, 308, 2134, 556, 644, 10098, 15, 187, 187, 510, 806, 3924, 27, 309, 37326, 5161, 3153, 13, 14631, 253, 309, 37326, 6807, 13, 4886, 253, 3114, 457, 84, 12939, 689, 281, 7335, 471, 13, 21006, 690, 31734, 13, 309, 37326, 327, 6431, 2791, 13, 17355, 715, 253, 1533, 187, 187, 510, 1273, 3924, 27, 13633, 309, 37326, 457, 84, 2780, 408, 414, 13, 1527, 309, 37326, 281, 3780, 326, 971, 281, 1973, 327, 1755, 273, 253, 309, 37326, 2990, 187, 187, 510, 2626, 3924, 27, 2440, 273, 10309, 313, 10408, 434, 1416, 310, 500, 2966, 2199, 582, 247, 7138, 747, 1511, 273, 2494, 23171, 323, 37377, 13, 247, 10309, 7092, 556, 379, 323, 309, 37326, 457, 84, 2802, 36, 6434, 13283, 1159, 457, 187, 187, 13745, 23569, 309, 37326, 10589, 187, 187, 30138, 296, 2275, 80, 187, 187, 6075, 463, 90, 34784, 10024, 3129, 80, 187, 187, 52, 1326, 489, 74, 12278, 729, 187, 187, 37, 5240, 1479, 3697, 1914, 254, 187, 187, 9867, 625, 670, 309, 37326, 2285, 15, 187, 187, 38, 16654, 187, 187, 1992, 1265, 271, 1527, 2603, 2199, 310, 417, 1892, 13, 533, 281, 1756, 352, 310, 16088, 2834, 15, 380, 5547, 1527, 2603, 2199, 878, 247, 1270, 17493, 8704, 352, 15, 380, 1921, 323, 352, 310, 2969, 15, 444, 16654, 588, 7257, 1048, 1307, 32435, 15, 187, 187, 42, 37326, 275, 4240, 187, 187, 42, 37326, 2168, 4262, 7357, 253, 990, 273, 4022, 689, 495, 3041, 5547, 13122, 15, 3771, 281, 9287, 368, 13, 309, 37326, 310, 253, 1533, 457, 84, 806, 5865, 10858, 985, 1293, 667, 8128, 15, 187, 187, 9586, 2167, 309, 37326, 556, 644, 2168, 10098, 13, 253, 807, 4240, 588, 320, 253, 806, 807, 672, 1943, 2544, 1265, 12952, 15, 1707, 403, 8783, 273, 6493, 326, 403, 275, 6684, 4438, 313, 17480, 4104, 10, 285, 588, 320, 3585, 4206, 285, 8027, 3517, 15, 187, 187, 510, 1180, 581, 309, 37326, 11674, 273, 4240, 310, 281, 1056, 253, 309, 37326, 5147, 13722, 31337, 285, 11453, 15, 9375, 281, 3939, 5161, 2285, 285, 14448, 342, 253, 3114, 253, 309, 37326, 10315, 18758, 1059, 2427, 3153, 13, 18805, 23138, 323, 10469, 556, 644, 4439, 285, 9940, 14713, 323, 40727, 1475, 309, 37326, 310, 5675, 313, 8780, 13747, 275, 34619, 13, 13814, 13, 330, 27396, 8595, 285, 3617, 481, 187, 187, 1276, 310, 309, 37326, 7889, 3364, 285, 2139, 310, 352, 594, 1774, 32, 187, 187, 510, 309, 37326, 7889, 3364, 310, 1060, 323, 12259, 285, 3400, 731, 5657, 13, 28275, 285, 3126, 323, 773, 6309, 2127, 6598, 1583, 1053, 626, 878, 281, 6184, 2712, 13, 4758, 598, 616, 5578, 390, 622, 13, 597, 403, 417, 11639, 13, 597, 476, 816, 2127, 15, 380, 7889, 3364, 310, 1774, 984, 309, 37326, 310, 1527, 2603, 13, 594, 3780, 476, 10078, 327, 2440, 15, 309, 37326, 3198, 625, 12259, 665, 1973, 5161, 285, 11222, 281, 1756, 253, 17493, 285, 1056, 352, 1533, 14, 4363, 15, 187, 187, 4045, 368, 971, 281, 10078, 32, 26779, 309, 37326, 15, 187, 187, 42, 37326, 6807, 310, 5506, 323, 6684, 285, 11850, 253, 5161, 1527, 2603, 7241, 309, 37326, 15, 733, 310, 9856, 275, 6176, 347, 271, 3565, 1327, 14, 15608, 659, 2094, 1947, 15, 187, 187, 17642, 6667, 273, 309, 37326, 897, 187, 187, 2512, 403, 1142, 353, 19, 46, 6667, 533, 604, 368, 403, 2819, 323, 581, 326, 310, 18996, 4802, 281, 634, 1495, 987, 1024, 13, 2451, 436, 581, 15, 187, 187, 510, 8573, 4602, 310, 2530, 313, 42022, 281, 368, 10, 407, 4014 ]

we need to provide a network for machines to communicate with another machines (devices). We aren’t talking just about Internet of Things (IoT), now we are talking about Internet of Everything (IoE). IOTA creates an environment for IoE Now, IOTA is coming! IOTA Foundation create an environment for Internet of Everything (IoE). The IOTA platform can be presented as a bridge via systems can connect, communicate and evolve. The interconnectivity is the key for our new economy. With interconnectivity comes incredible huge amount of data that devices send and receive every seconds. To take full benefit from the IoT and IoE we have to find a way how to connect the billions of cyber-physical systems together. The network we set up has to gain our trust. Human kind is nowadays dependant on Internet. Can you imagine what will happen if the Internet goes down. Even just for one day or one hour. The future of fully operational status of our society and economy lies in the 24 hour-stable communication (interconnection). The Internet is by far the most efficient medium but we can’t afford to use just that. The consequences of depending on one single channel would be catastrophic. IOTA developed a protocol on which the machines can communicate via other channels, such as Bluetooth, Z-wave, ZigBee or LoRa. The future of connectivity might lie beyond the Internet itself. IoE: Sensors as an example The market of IoE rapidly increasing. Let's talk about sensors, the area of market that you might not heard about yet, but will have significant impact on our economy and social life. The number of sensors especially due to demand in SmartHomes and SmartCities is growing like crazy. Sending and receiving data is just the beginning of the chain. There is no doubt we will need more computational power. The big data in our new economy needs to be analyzed first and reported as soon as possible. Cloud storage nowadays cannot provide us real-time results that we require. We need smart sensors, that have computational ability itself and are able to work with other stations as well. Instead of Cloud computing we talk about Fog computing and Mist computing. Find the difference in an easy explanation. There will be billions of sensors by the 2025. Data won't be shared freely and that is a potential for cooperation among companies and individuals. IOTA will provide the platform for exchange (data for money). Just imagine that once you gather some data, you can sell them, as well as you can sell your free storage. Selling it means to get compensation with IOTA currency. There won't be just distributed computing, data and storage, but also distributed brandwith and energy. The future of Internet of Everything is coming. But untill it reaches our everyday life, we need to do some changes starting on recognition of smart devices. Identity of Things (IDoT) To make IoT ecosystem secure, we need to think about machines and devices differently, not just as a metal things without life. We need to consider each device as its own identity. Why? Because the identity carries some attributes and we cannot securely and efficiently work with IoT without knowing more. One of the biggest challenge for IoT will be the maintenance. Creation is hard process, but to maintain IoT (means also keep them resilient) is a long-term task, that cannot be undervalued. Look at any software and application that you use on PC or smartphone. How many times did you update it? Maintenance is a new angle of re-creation process. So far we use one unique identifier for devices, but that is not enough to satisfy our future needs — secure status and smooth long term usage. Identity of Things (IDoT) will become a new standard. The question is when it will happen. To give you an idea, we need to create IoT with some specific attributes, such as: who manufactured it when it was deployed what is the expected life time cycle who owns it what data is it gathering For deeper understanding I recommend you to read IOTA development roadmap. The biggest chalenge for society 2.0 With growing number of smart devices, there will be more data traffic. Data means informations and informations are money (or power, if you prefer). All the IoT (IoE) communication must be encrypted. One of the IOTA modul is called Masked Authenticated Messaging and its job is to secure and encrypt entire data stream. Only authorized parties will be able to read and reconstruct the stream. Encrypting the data streaming is the whole area that needs to be developed with a new way of approach. Far by most important is security. As our society technologically grow, we became dependant on software and hardware. We become more vulnerable to software or hardware malfunction or hacker's attacks. The future will take place even more in cyberspace, so security should be our first priority when we aiming for a tech change. Quantum computation and mechanics cause headaches to security engineers, because in the coming decades we can see very real possibility of scalable quantum computers. This will disrupt most of cryptographic protocols used today. So in another words, our world can become insecure with quantum computers. If you want to go more in depth, have a look on article How secure will our data be in the post-quantum era? No-one can be ready for this cybersecurity challenge, but IOTA is very proactive in solving solution. It deploys 2 separate mechanisms to safe-guard against quantum threats. You can read about security issues in the Tagle whitepaper. All in one solution is replaced by layers and eXtension Interface The approach for developing IOTA is not to build all in one universal solution, but instead design and engineering core simple principles (they call it often underlaying edger protocol) and then extend its utility through the IOTA eXtension Interface (IXI). The advantage is that anyone can build IXI for their own needs, it is fast and very flexible solution to speed up development. IXI modules are the reason why IOTA will stay lightweight and optimized. History of IOTA We heard about IOTA first in 2014 when a small team developed a brand new type of microprocessor for IoT and distributed computing. The persistent problem in deeper development was lack of a clear incentive for interoperability. It was crucial. Machine 2 machine economy is and will be based on micro-transaction. It is getting better but even today we still face prohibitive fees, inflexibility and perpetual problems with scalability in blockchain development. IOTA was born as an idea to create a compensation layer that will act as the building blocks of the Economy of Things where machines can trade resources effectively and securely on-demand. IOTA main network went live on 11th July. The protocol and data transfer on the distributed and decentralized Tangle has been launched. The first stage: IOTA core live, establishing the IOTA Foundation, moving the community’s chat over to Slack, completing some partnerships, IOTA on exchange market, spreading into the world The second stage: extending IOTA’s utillity, open IOTA to anyone that want to build on top of the IOTA network The third stage: development of hardware (project's name is Jinn project), a brand new type of microprocessor for IoT, a hardware implementation hasher for IOTA’s ‘Curl hash function’ Core founding IOTA Team Sonstebo Sergey Ivancheglo Serguei Popov Dominik Schiener Find more about IOTA team. Ecosystem To start an open source project is not hard, but to grow it is incredibly difficult. The successful open source project need a great ecosystem surrounding it. The reason for it is simple. Ecosystem will deliver long term sustainability. IOTA in 2017 IOTA already proceed till the end of 2016 over 3 million successful transactions. Just to remind you, IOTA is the world’s first digital settlement system without any fees. Even though IOTA has been already launched, the year 2017 will be the first year when big changes start occurring. There are lots of projects that are in developing mode (since 2015) and will be reviled and launch soon. The number one IOTA priority of 2017 is to make the IOTA platform developer inviting and friendly. Thanks to active core team and collaboration with the community the IOTA Lightwallet went live, Mobile wallet for Android has been released and dedicated hub for tutorials around IOTA is growing (client libraries in Javascript, Python, C#, Java and Go). What is IOTA Sandbox and why is it so important? The IOTA Sandbox is here for developers and provides them tools, utilities and environment for “just code”. They don't need to download anything, setting up their PC or app, they are not disturb, they can just code. The Sandbox is important because IOTA is open source, so anyone can participate on development. IOTA needs more developers who build core and apps to grow the ecosystem and make it world-wide. Do you want to participate? Learn IOTA. IOTA Foundation is responsible for developing and maintaining the core open source protocol IOTA. It is registered in Germany as an official non-profit Stiftung. Real examples of IOTA use There are many M2M examples but if you are looking for one that is tightly connected to your life right now, check this one. The internet connection is provided (sold to you) by tele