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<|startoftext|><L>Cc1cc<mask_1:1>c(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1<mask_1:1> | 3 | 5 | 1 | 2nn | 1 | Cc1cc2c(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | 2 |
<|startoftext|><L>Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)<mask_1:6>2c(C)n1<mask_1:6> | 1 | 34 | 6 | n | 6 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)c(=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | c(=O)n |
<|startoftext|><L>Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c<mask_1:5>C)n1<mask_1:5> | 1 | 37 | 5 | ( | 5 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C(C)C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | (C(C) |
<|startoftext|><L>Cc1cc2<mask_1:4>CCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1<mask_1:4> | 5 | 6 | 4 | nnc(S | 4 | Cc1cc2nnc(CCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | nnc( |
<|startoftext|><L>Cc1cc2nnc(SC<mask_1:2>CCN3C(=O)NC(C)(C)C3=O)n2c(C)n1<mask_1:2> | 0 | 12 | 2 | 2 | Cc1cc2nnc(SCCCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | CC |
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<|startoftext|><L>Cc1cc2nnc(SCCCN3C(=O)NC(<mask_1:3>C3=O)n2c(C)n1<mask_1:3> | 5 | 24 | 3 | C)(C) | 3 | Cc1cc2nnc(SCCCN3C(=O)NC(C)CC3=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | C)C |
<|startoftext|><L>Cc1c<mask_1:2>c(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1<mask_1:2> | 4 | 4 | 2 | c2nn | 2 | Cc1cc2c(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | c2 |
<|startoftext|><L>Cc1cc2nnc(SCCCN3<mask_1:5>C(=O)NC(C)(C)C3=O)n2c(C)n1<mask_1:5> | 0 | 16 | 5 | 5 | Cc1cc2nnc(SCCCN3C(=O)C(=O)NC(C)(C)C3=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | C(=O) |
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<|startoftext|><L>Cc1cc2nn<mask_1:5>N3C(=O)NC(C)(C)C3=O)n2c(C)n1<mask_1:5> | 6 | 8 | 5 | c(SCCC | 5 | Cc1cc2nnc(SCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | c(SCC |
<|startoftext|><L>Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)<mask_1:2>O)n2c(C)n1<mask_1:2> | 3 | 29 | 2 | C3= | 2 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3O)n2c(C)n1 | Cc1cc2nnc(SCCCN3C(=O)NC(C)(C)C3=O)n2c(C)n1 | C3 |
<|startoftext|><L>Nc1nnc(S<mask_1:5>2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1<mask_1:5> | 2 | 8 | 5 | Cc | 5 | Nc1nnc(SCCCOc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | CCCOc |
<|startoftext|><L>Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(<mask_1:6>c4ccccc4)CC3)n2)s1<mask_1:6> | 1 | 29 | 6 | C | 6 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(C(=O)Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | C(=O)C |
<|startoftext|><L>Nc1nnc(SCc2cc(=O)[nH]c(<mask_1:5>N(Cc4ccccc4)CC3)n2)s1<mask_1:5> | 4 | 23 | 5 | N3CC | 5 | Nc1nnc(SCc2cc(=O)[nH]c(NC3CCN(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | NC3CC |
<|startoftext|><L>Nc1nnc(SCc2cc(=O)[nH]c(N<mask_1:7>3CCN(Cc4ccccc4)CC3)n2)s1<mask_1:7> | 0 | 24 | 7 | 7 | Nc1nnc(SCc2cc(=O)[nH]c(NC(=S)NC3CCN(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | C(=S)NC |
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<|startoftext|><L>Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(C<mask_1:6>4ccccc4)CC3)n2)s1<mask_1:6> | 1 | 30 | 6 | c | 6 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(C/C=C/c4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | /C=C/c |
<|startoftext|><L>Nc1nnc(SCc2cc<mask_1:2>nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1<mask_1:2> | 5 | 13 | 2 | (=O)[ | 2 | Nc1nnc(SCc2ccc[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | c[ |
<|startoftext|><L>Nc1nnc<mask_1:5>SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1<mask_1:5> | 1 | 6 | 5 | ( | 5 | Nc1nnc(SCCCSCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | (SCCC |
<|startoftext|><L>Nc1nnc(SCc2cc(=O)[nH]c(N3<mask_1:5>(Cc4ccccc4)CC3)n2)s1<mask_1:5> | 3 | 25 | 5 | CCN | 5 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCC=C(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | CCC=C |
<|startoftext|><L>Nc1nnc(SCc2cc(=<mask_1:2>c(N3CCN(Cc4ccccc4)CC3)n2)s1<mask_1:2> | 6 | 15 | 2 | O)[nH] | 2 | Nc1nnc(SCc2cc(=O)c(N3CCN(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | O) |
<|startoftext|><L>Nc1nnc(SC<mask_1:6>cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1<mask_1:6> | 2 | 9 | 6 | c2 | 6 | Nc1nnc(SC(=O)c2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | Nc1nnc(SCc2cc(=O)[nH]c(N3CCN(Cc4ccccc4)CC3)n2)s1 | (=O)c2 |
<|startoftext|><L>C<mask_1:2>c2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1<mask_1:2> | 6 | 1 | 2 | CCCc1o | 2 | Cc1c2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | c1 |
<|startoftext|><L><mask_1:6>Cc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1<mask_1:6> | 3 | 0 | 6 | CCC | 6 | O=C(O)Cc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | O=C(O) |
<|startoftext|><L>CCCCc1oc2ccccc2c<mask_1:6>)Nc1ccc(OCCN(C)C)cc1<mask_1:6> | 5 | 16 | 6 | 1C(=O | 6 | CCCCc1oc2ccccc2c1CC(=O)Nc1ccc(OCCN(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | 1CC(=O |
<|startoftext|><L>CCCCc1oc2ccccc2c1C(=O)Nc1cc<mask_1:5>(C)C)cc1<mask_1:5> | 6 | 27 | 5 | c(OCCN | 5 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCC(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | c(OCC |
<|startoftext|><L>CCCCc1oc2ccccc2c1C(=O)Nc1c<mask_1:4>OCCN(C)C)cc1<mask_1:4> | 3 | 26 | 4 | cc( | 4 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(COCCN(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | cc(C |
<|startoftext|><L>CCCCc1oc<mask_1:6>ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1<mask_1:6> | 1 | 8 | 6 | 2 | 6 | CCCCc1oc(=O)c2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | (=O)c2 |
<|startoftext|><L>CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCC<mask_1:4>cc1<mask_1:4> | 6 | 32 | 4 | N(C)C) | 4 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCCOC)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | COC) |
<|startoftext|><L>CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OC<mask_1:3>)C)cc1<mask_1:3> | 4 | 31 | 3 | CN(C | 3 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCC(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | C(C |
<|startoftext|><L>CCCCc1oc2ccccc<mask_1:6>C(=O)Nc1ccc(OCCN(C)C)cc1<mask_1:6> | 3 | 14 | 6 | 2c1 | 6 | CCCCc1oc2ccccc2c1CSCC(=O)Nc1ccc(OCCN(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | 2c1CSC |
<|startoftext|><L>CCCCc1oc2c<mask_1:6>cc2c1C(=O)Nc1ccc(OCCN(C)C)cc1<mask_1:6> | 2 | 10 | 6 | cc | 6 | CCCCc1oc2cc(Cl)ccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | CCCCc1oc2ccccc2c1C(=O)Nc1ccc(OCCN(C)C)cc1 | c(Cl)c |
<|startoftext|><L>C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc<mask_1:2>2)SC1=S<mask_1:2> | 4 | 42 | 2 | 3F)o | 2 | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3)2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | 3) |
<|startoftext|><L>C[C@@H](C(=O)O)N1C(=O)/C(=C\c2cc<mask_1:3>-c3ccccc3F)o2)SC1=S<mask_1:3> | 2 | 32 | 3 | c( | 3 | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(C-c3ccccc3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | c(C |
<|startoftext|><L>C[C@@H](C(=O<mask_1:6>C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S<mask_1:6> | 5 | 12 | 6 | )O)N1 | 6 | C[C@@H](C(=O)O)N1NC(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | )O)N1N |
<|startoftext|><L>C[C@@H](C(=O)O)<mask_1:7>C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S<mask_1:7> | 2 | 15 | 7 | N1 | 7 | C[C@@H](C(=O)O)N1C(=O)C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | N1C(=O) |
<|startoftext|><L>C<mask_1:1>[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S<mask_1:1> | 0 | 1 | 1 | 1 | CC[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | C |
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<|startoftext|><L>C[C@@H<mask_1:2>O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S<mask_1:2> | 7 | 6 | 2 | ](C(=O) | 2 | C[C@@H](O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | ]( |
<|startoftext|><L>C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(<mask_1:1>3ccccc3F)o2)SC1=S<mask_1:1> | 2 | 34 | 1 | -c | 1 | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(c3ccccc3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | c |
<|startoftext|><L>C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F<mask_1:1>2)SC1=S<mask_1:1> | 2 | 44 | 1 | )o | 1 | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | ) |
<|startoftext|><L>C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3cc<mask_1:6>c3F)o2)SC1=S<mask_1:6> | 2 | 39 | 6 | cc | 6 | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3cccc(Cl)c3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | cc(Cl) |
<|startoftext|><L>C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3cccc<mask_1:5>3F)o2)SC1=S<mask_1:5> | 1 | 41 | 5 | c | 5 | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3cccc(Cl)c3F)o2)SC1=S | C[C@@H](C(=O)O)N1C(=O)/C(=C\c2ccc(-c3ccccc3F)o2)SC1=S | (Cl)c |
<|startoftext|><L>CC(C)(C)c1n[nH]c<mask_1:4>CNCc1nc(-c2ccccc2)cs1<mask_1:4> | 2 | 16 | 4 | c1 | 4 | CC(C)(C)c1n[nH]cc1CCCNCc1nc(-c2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | c1CC |
<|startoftext|><L>CC(<mask_1:2>)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1<mask_1:2> | 1 | 3 | 2 | C | 2 | CC(Cl)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | Cl |
<|startoftext|><L>CC(C)(C<mask_1:4>n[nH]cc1CNCc1nc(-c2ccccc2)cs1<mask_1:4> | 3 | 7 | 4 | )c1 | 4 | CC(C)(C)Cc1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | )Cc1 |
<|startoftext|><L>C<mask_1:3>(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1<mask_1:3> | 1 | 1 | 3 | C | 3 | COCC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | OCC |
<|startoftext|><L>CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2<mask_1:4>1<mask_1:4> | 3 | 35 | 4 | )cs | 4 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2F)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | F)cs |
<|startoftext|><L>CC(C)(C<mask_1:5>c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1<mask_1:5> | 1 | 7 | 5 | ) | 5 | CC(C)(C)N(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | )N(C) |
<|startoftext|><L>CC(C)(C)c1n[nH]cc1CNCc1nc(<mask_1:4>c2ccccc2)cs1<mask_1:4> | 1 | 26 | 4 | - | 4 | CC(C)(C)c1n[nH]cc1CNCc1nc(C#CCc2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | C#CC |
<|startoftext|><L>CC<mask_1:1>(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1<mask_1:1> | 0 | 2 | 1 | 1 | CCC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | C |
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<|startoftext|><L>CC(C)(C)c1n[nH]cc1CNCc1nc<mask_1:4>cccc2)cs1<mask_1:4> | 5 | 25 | 4 | (-c2c | 4 | CC(C)(C)c1n[nH]cc1CNCc1nc(-n2cccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | (-n2 |
<|startoftext|><L>CC(C)(C)c1n[nH<mask_1:5>c1CNCc1nc(-c2ccccc2)cs1<mask_1:5> | 2 | 14 | 5 | ]c | 5 | CC(C)(C)c1n[nH]c(N)c1CNCc1nc(-c2ccccc2)cs1 | CC(C)(C)c1n[nH]cc1CNCc1nc(-c2ccccc2)cs1 | ]c(N) |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2c<mask_1:9>OC)c2)c1<mask_1:9> | 8 | 46 | 9 | cc(OC)c( | 9 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(COC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | cc(OC)c(C |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C<mask_1:5>C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1<mask_1:5> | 4 | 22 | 5 | 3=C( | 5 | COc1cccc([C@H]2CC(=O)C3=C(CC2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | 3=C(C |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(<mask_1:5>C)c(OC)c2)c1<mask_1:5> | 1 | 49 | 5 | O | 5 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC(C)C)c(OC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | OC(C) |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C<mask_1:3>C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1<mask_1:3> | 2 | 22 | 3 | 3= | 3 | COc1cccc([C@H]2CC(=O)C3=CC(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | 3=C |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc<mask_1:8>c2)c1<mask_1:8> | 9 | 48 | 8 | (OC)c(OC) | 8 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2cccc(N(C)C)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | c(N(C)C) |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(<mask_1:6>C[C@@H]3c2ccc(OC)c(OC)c2)c1<mask_1:6> | 9 | 26 | 6 | C2)NC(=O) | 6 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC=C[C@@H]3c2ccc(OC)c(OC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | C2)NC= |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc<mask_1:8>C)c2)c1<mask_1:8> | 7 | 48 | 8 | (OC)c(O | 8 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(Cl)c(OCC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | (Cl)c(OC |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(C2)<mask_1:2>O)C[C@@H]3c2ccc(OC)c(OC)c2)c1<mask_1:2> | 4 | 29 | 2 | NC(= | 2 | COc1cccc([C@H]2CC(=O)C3=C(C2)N(O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | N( |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c<mask_1:5>)c1<mask_1:5> | 6 | 53 | 5 | (OC)c2 | 5 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(O)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | (O)c2 |
<|startoftext|><L>COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2cc<mask_1:4>OC)c(OC)c2)c1<mask_1:4> | 2 | 47 | 4 | c( | 4 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OCOC)c(OC)c2)c1 | COc1cccc([C@H]2CC(=O)C3=C(C2)NC(=O)C[C@@H]3c2ccc(OC)c(OC)c2)c1 | c(OC |
<|startoftext|><L>O=<mask_1:2>c1nncn1-c1ccccc1)c1cccc2cn[nH]c12<mask_1:2> | 3 | 2 | 2 | C(N | 2 | O=C(c1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | C( |
<|startoftext|><L>O=C(Nc1nncn1-<mask_1:3>1ccccc1)c1cccc2cn[nH]c12<mask_1:3> | 1 | 13 | 3 | c | 3 | O=C(Nc1nncn1-CCc1ccccc1)c1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | CCc |
<|startoftext|><L>O=C(Nc1nncn1-c1ccccc1)<mask_1:4>cccc2cn[nH]c12<mask_1:4> | 2 | 22 | 4 | c1 | 4 | O=C(Nc1nncn1-c1ccccc1)NCc1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | NCc1 |
<|startoftext|><L>O=C(<mask_1:3>1nncn1-c1ccccc1)c1cccc2cn[nH]c12<mask_1:3> | 2 | 4 | 3 | Nc | 3 | O=C(NCc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | NCc |
<|startoftext|><L>O=C(Nc1nncn1-c1ccccc1)c1<mask_1:5>c2cn[nH]c12<mask_1:5> | 3 | 24 | 5 | ccc | 5 | O=C(Nc1nncn1-c1ccccc1)c1c[nH]c2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | c[nH] |
<|startoftext|><L>O=C(Nc1nncn1-c1ccc<mask_1:3>c1cccc2cn[nH]c12<mask_1:3> | 4 | 18 | 3 | cc1) | 3 | O=C(Nc1nncn1-c1cccs1)c1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | s1) |
<|startoftext|><L>O=C(Nc1nn<mask_1:5>c1ccccc1)c1cccc2cn[nH]c12<mask_1:5> | 4 | 9 | 5 | cn1- | 5 | O=C(Nc1nncn1CCc1ccccc1)c1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | cn1CC |
<|startoftext|><L>O=C(<mask_1:5>ncn1-c1ccccc1)c1cccc2cn[nH]c12<mask_1:5> | 4 | 4 | 5 | Nc1n | 5 | O=C(NCc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | NCc1n |
<|startoftext|><L>O=C(Nc1nncn1-c1ccccc1)c<mask_1:3>c2cn[nH]c12<mask_1:3> | 4 | 23 | 3 | 1ccc | 3 | O=C(Nc1nncn1-c1ccccc1)c1csc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | 1cs |
<|startoftext|><L>O=C<mask_1:4>c1nncn1-c1ccccc1)c1cccc2cn[nH]c12<mask_1:4> | 2 | 3 | 4 | (N | 4 | O=C(NCCc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | O=C(Nc1nncn1-c1ccccc1)c1cccc2cn[nH]c12 | (NCC |
<|startoftext|><L>O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2nccc<mask_1:2>2)CC1)OCc1ccccc1<mask_1:2> | 1 | 38 | 2 | n | 1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | n |
<|startoftext|><L>O=C(N<mask_1:5>H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1<mask_1:5> | 3 | 5 | 5 | [C@ | 5 | O=C(NC[C@@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | C[C@@ |
<|startoftext|><L>O<mask_1:8>H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1<mask_1:8> | 7 | 1 | 8 | =C(N[C@ | 8 | O=C(N[C@@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | =C(N[C@@ |
<|startoftext|><L>O=C(N[C@H](Cc1ccccc1)C(=O)N1CC<mask_1:6>c2ncccn2)CC1)OCc1ccccc1<mask_1:6> | 2 | 30 | 6 | N( | 6 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(CCCNc2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | N(CCCN |
<|startoftext|><L>O=C(N[C@H](Cc1ccccc1)C(=O)N1C<mask_1:5>2ncccn2)CC1)OCc1ccccc1<mask_1:5> | 4 | 29 | 5 | CN(c | 5 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(Cc2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | CN(Cc |
<|startoftext|><L>O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OC<mask_1:8>c1ccccc1<mask_1:8> | 0 | 47 | 8 | 8 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1c1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | c1ccccc1 |
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<|startoftext|><L>O=C(N[C@H](Cc1ccccc1)C(=O<mask_1:6>)N1CCN(c2ncccn2)CC1)OCc1ccccc1<mask_1:6> | 0 | 25 | 6 | 6 | O=C(N[C@H](Cc1ccccc1)C(=O)NC(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | )NC(=O |
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<|startoftext|><L>O=C(N[C@H](C<mask_1:1>cc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1<mask_1:1> | 5 | 12 | 1 | c1ccc | 1 | O=C(N[C@H](C1cc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | 1 |
<|startoftext|><L>O=C(N<mask_1:8>H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1<mask_1:8> | 3 | 5 | 8 | [C@ | 8 | O=C(NC(=O)[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | C(=O)[C@ |
<|startoftext|><L>O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)<mask_1:7>ccccc1<mask_1:7> | 4 | 45 | 7 | OCc1 | 7 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)C(=O)c1ccccc1 | O=C(N[C@H](Cc1ccccc1)C(=O)N1CCN(c2ncccn2)CC1)OCc1ccccc1 | C(=O)c1 |
<|startoftext|><L>Cc1ccc(S(<mask_1:4>O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1<mask_1:4> | 5 | 9 | 4 | =O)(= | 4 | Cc1ccc(S(=O)(O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | =O)( |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2<mask_1:1>)cc1<mask_1:1> | 5 | 43 | 1 | (N)CN | 1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2N)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | N |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@H]<mask_1:4>c3ccccc3)[C@@]2(N)CN)cc1<mask_1:4> | 7 | 21 | 4 | 2[C@H]( | 4 | Cc1ccc(S(=O)(=O)[C@H]2N(Cc3ccccc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | 2N(C |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccc<mask_1:7>[C@@]2(N)CN)cc1<mask_1:7> | 4 | 33 | 7 | cc3) | 7 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccc(F)cc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | (F)cc3) |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@<mask_1:5>[C@H](c3ccccc3)[C@@]2(N)CN)cc1<mask_1:5> | 3 | 19 | 5 | H]2 | 5 | Cc1ccc(S(=O)(=O)[C@@H]2O[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | @H]2O |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@H]2<mask_1:2>](c3ccccc3)[C@@]2(N)CN)cc1<mask_1:2> | 4 | 22 | 2 | [C@H | 2 | Cc1ccc(S(=O)(=O)[C@H]2[C](c3ccccc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | [C |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@H]2[C@H](<mask_1:3>3ccccc3)[C@@]2(N)CN)cc1<mask_1:3> | 1 | 28 | 3 | c | 3 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](CCc3ccccc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | CCc |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3cccc<mask_1:6>C@@]2(N)CN)cc1<mask_1:6> | 4 | 34 | 6 | c3)[ | 7 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3cccc(F)c3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | (F)c3)[ |
<|startoftext|><L>Cc1ccc(S(=O)(=O)[C@H<mask_1:5>C@H](c3ccccc3)[C@@]2(N)CN)cc1<mask_1:5> | 3 | 20 | 5 | ]2[ | 5 | Cc1ccc(S(=O)(=O)[C@H]2CS[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | ]2CS[ |
<|startoftext|><L>Cc1ccc(S(=O)(=O<mask_1:6>]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1<mask_1:6> | 5 | 15 | 6 | )[C@H | 6 | Cc1ccc(S(=O)(=O)[C@@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | Cc1ccc(S(=O)(=O)[C@H]2[C@H](c3ccccc3)[C@@]2(N)CN)cc1 | )[C@@H |
<|startoftext|><L>COCCN1C(=O)C[C@@](CC(=O)N<mask_1:9>[C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:9> | 5 | 25 | 9 | 2CCC( | 9 | COCCN1C(=O)C[C@@](CC(=O)N(C2CCN(C)[C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | (C2CCN(C) |
<|startoftext|><L>COCCN<mask_1:8>=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:8> | 3 | 5 | 8 | 1C( | 8 | COCCN1C(=O)C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | 1C(=O)C( |
<|startoftext|><L>COCCN1C(=O)C[C@@](CC(=O)N<mask_1:10>@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:10> | 7 | 25 | 10 | 2CCC([C | 10 | COCCN1C(=O)C[C@@](CC(=O)N2CCN(CCC[C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | 2CCN(CCC[C |
<|startoftext|><L>COCCN1C(=O)C[C@@](CC<mask_1:5>)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:5> | 3 | 20 | 5 | (=O | 5 | COCCN1C(=O)C[C@@](CCCC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | CC(=O |
<|startoftext|><L>COCCN1C(=O)C[C@@](C<mask_1:7>2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:7> | 6 | 19 | 7 | C(=O)N | 7 | COCCN1C(=O)C[C@@](CCC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | CC(=O)N |
<|startoftext|><L>COCCN1C(=O)C[C@@](CC(=O)N2CCC<mask_1:8>H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:8> | 5 | 29 | 8 | ([C@@ | 8 | COCCN1C(=O)C[C@@](CC(=O)N2CCC(O)(C[C@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | (O)(C[C@ |
<|startoftext|><L>COCCN1C(<mask_1:6>CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:6> | 10 | 8 | 6 | =O)C[C@@]( | 6 | COCCN1C(=O)CC(CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | =O)CC( |
<|startoftext|><L>COCCN1C(=O)C[C@@](CC(=O)N2CC<mask_1:5>H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:5> | 6 | 28 | 5 | C([C@@ | 5 | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | C([C@ |
<|startoftext|><L>COC<mask_1:5>(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:5> | 4 | 3 | 5 | CN1C | 5 | COCCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | CCN1C |
<|startoftext|><L>COCCN1C(=O)C[C@<mask_1:8>CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O<mask_1:8> | 3 | 15 | 8 | @]( | 8 | COCCN1C(=O)C[C@@](C(=O)CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | COCCN1C(=O)C[C@@](CC(=O)N2CCC([C@@H](O)c3ccccc3)CC2)(c2cccc(OC)c2)C1=O | @](C(=O) |