jarod0411/cm_v6_idx4 · Datasets at Hugging Face

prompt stringlengths 47 229	first_mask_count int64 0 16	first_start_index int64 0 176	first_mask_gen_count int64 1 16	first_mask_tokens stringlengths 0 16	first_mask_gen_count_real int64 0 19	generated_smiles stringlengths 10 199	original_smiles stringlengths 10 192	generated_tokens stringlengths 0 19
<\|startoftext\|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1<mask_1:4>(=O)c1ccoc1C<mask_1:4>	2	30	4	NC	4	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1N(C)(=O)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	N(C)
<\|startoftext\|><L>Cc1noc(C)c1CO[C@H<mask_1:4>COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:4>	2	17	4	]1	4	Cc1noc(C)c1CO[C@H]1CCCOCC[C@@H]1NC(=O)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	]1CC
<\|startoftext\|><L>Cc<mask_1:3>C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:3>	5	2	3	1noc(	3	Cc1n(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	1n(
<\|startoftext\|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)<mask_1:5>1C<mask_1:5>	6	36	5	c1ccoc	6	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1cnoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	c1cnoc
<\|startoftext\|><L>Cc1noc(C)c1CO[<mask_1:1>H]1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:1>	2	14	1	C@	1	Cc1noc(C)c1CO[CH]1COCC[C@@H]1NC(=O)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	C
<\|startoftext\|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1<mask_1:4>c1ccoc1C<mask_1:4>	6	30	4	NC(=O)	4	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1N(C)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	N(C)
<\|startoftext\|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(<mask_1:5>c1ccoc1C<mask_1:5>	3	33	5	=O)	5	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)NCc1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	=O)NC
<\|startoftext\|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]<mask_1:6>(=O)c1ccoc1C<mask_1:6>	3	29	6	1NC	6	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1N(C)C(=O)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	1N(C)C
<\|startoftext\|><L>Cc1no<mask_1:2>1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:2>	5	5	2	c(C)c	2	Cc1nonc1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	nc
<\|startoftext\|><L>Cc1noc(C)c1C<mask_1:4>1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:4>	6	12	4	O[C@H]	4	Cc1noc(C)c1COCCN1COCC[C@@H]1NC(=O)c1ccoc1C	Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C	OCCN
<\|startoftext\|><L>C[C@H](CN[C@H](Cc1ccncc1<mask_1:1>F)F)N1CCOC[C@H]1C<mask_1:1>	6	24	1	)C(F)(	1	C[C@H](CN[C@H](Cc1ccncc1CF)F)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C
<\|startoftext\|><L>C[C@H](<mask_1:2>CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:2>	0	7	2		2	C[C@H](CCCN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	CC
<\|startoftext\|><L>C[<mask_1:5>C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:5>	0	2	5		5	C[C@H][C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C@H][
<\|startoftext\|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1<mask_1:2>CCOC[C@H]1C<mask_1:2>	0	36	2		2	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCCCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	CC
<\|startoftext\|><L>C[C@H]<mask_1:3>N[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:3>	2	6	3	(C	3	C[C@H](CCN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	(CC
<\|startoftext\|><L>C[C@H](CN[C@H](Cc1ccncc1)<mask_1:7>(F)(F)F)N1CCOC[C@H]1C<mask_1:7>	1	25	7	C	7	C[C@H](CN[C@H](Cc1ccncc1)C(=O)CC(F)(F)F)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C(=O)CC
<\|startoftext\|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F)(F<mask_1:7>COC[C@H]1C<mask_1:7>	6	31	7	)F)N1C	7	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)CN1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	)F)CN1C
<\|startoftext\|><L>C[C@H](CN[C@H](<mask_1:3>c1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:3>	7	15	3	Cc1ccnc	3	C[C@H](CN[C@H](C1Cc1)C(F)(F)F)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C1C
<\|startoftext\|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F<mask_1:6>)N1CCOC[C@H]1C<mask_1:6>	5	28	6	)(F)F	5	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	)(F)F
<\|startoftext\|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F<mask_1:6>N1CCOC[C@H]1C<mask_1:6>	1	33	6	)	6	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)C(=O)N1CCOC[C@H]1C	C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C	)C(=O)
<\|startoftext\|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C<mask_1:9>@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:9>	0	36	9		9	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@@H](C)[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	@@H](C)[C
<\|startoftext\|><L>CC(C)c1ccc(N2/C(=N\C(=O)<mask_1:8>ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:8>	2	24	8	c3	8	CC(C)c1ccc(N2/C(=N\C(=O)C(=O)Cc3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	C(=O)Cc3
<\|startoftext\|><L>CC(C)c1c<mask_1:7>C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:7>	6	8	7	cc(N2/	7	CC(C)c1ccc(CN2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	cc(CN2/
<\|startoftext\|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[<mask_1:6>)cc1<mask_1:6>	7	52	6	C@@H]32	6	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	C@H]32
<\|startoftext\|><L>CC(C)c1ccc<mask_1:9>N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:9>	7	10	9	(N2/C(=	9	CC(C)c1ccc(N2/C(=N\N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	(N2/C(=N\
<\|startoftext\|><L>CC(C)c1ccc(N2/C(=N\C<mask_1:5>(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:5>	0	20	5		5	CC(C)c1ccc(N2/C(=N\C(=O)C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	(=O)C
<\|startoftext\|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccc<mask_1:1>3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:1>	2	29	1	cc	1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccco3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	o
<\|startoftext\|><L>CC(C)c1ccc(N2/C(=N\C(=<mask_1:7>cccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:7>	5	22	7	O)c3c	7	CC(C)c1ccc(N2/C(=N\C(=O)COc3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	O)COc3c
<\|startoftext\|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3<mask_1:7>@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:7>	4	32	7	)S[C	7	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3Cl)S[C@@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	Cl)S[C@
<\|startoftext\|><L>CC(C)c1ccc(N2/C(<mask_1:8>C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:8>	3	16	8	=N\	8	CC(C)c1ccc(N2/C(=N\C(=O)C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1	=N\C(=O)
<\|startoftext\|><L>CN1CCN(<mask_1:6>=O)[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:6>	2	7	6	C(	6	CN1CCN(CCCNC(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	CCCNC(
<\|startoftext\|><L>CN1CCN(C(=O)<mask_1:3>[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:3>	0	12	3		3	CN1CCN(C(=O)NCC[C@H](Sc2ccccc2)c2ccccc2)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	NCC
<\|startoftext\|><L>CN1CCN(C(=O)[C@H](Sc2ccccc2)c2cc<mask_1:6>)CC1<mask_1:6>	4	32	6	ccc2	6	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2Cl)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	ccc2Cl
<\|startoftext\|><L>CN1CCN(C(=O<mask_1:5>(Sc2ccccc2)c2ccccc2)CC1<mask_1:5>	6	11	5	)[C@H]	5	CN1CCN(C(=O)C(O)(Sc2ccccc2)c2ccccc2)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	)C(O)
<\|startoftext\|><L>CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2<mask_1:5>C1<mask_1:5>	2	36	5	)C	5	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)C(O)C1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	)C(O)
<\|startoftext\|><L>CN1CC<mask_1:4>(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:4>	3	5	4	N(C	4	CN1CCC(NC(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	C(NC
<\|startoftext\|><L>C<mask_1:1>(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:1>	5	1	1	N1CCN	1	C1(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	1
<\|startoftext\|><L>CN1CCN(C(=O<mask_1:6>C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:6>	2	11	6	)[	6	CN1CCN(C(=O)CCCC[C@H](Sc2ccccc2)c2ccccc2)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	)CCCC[
<\|startoftext\|><L>CN1CCN(C(=O)[C@H](Sc2cc<mask_1:6>c2)c2ccccc2)CC1<mask_1:6>	2	23	6	cc	6	CN1CCN(C(=O)[C@H](Sc2ccc(Cl)cc2)c2ccccc2)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	c(Cl)c
<\|startoftext\|><L>CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2<mask_1:6>CC1<mask_1:6>	1	36	6	)	6	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)C(=O)CC1	CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1	)C(=O)
<\|startoftext\|><L>Cc1nc(-c2ccc([C<mask_1:6>]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:6>	2	15	6	@H	6	Cc1nc(-c2ccc([C@H][C@]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	@H][C@
<\|startoftext\|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=<mask_1:7>(C)C)C3)nc2)sc1C<mask_1:7>	3	31	7	O)N	7	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)CC(C)(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	O)CC(C)
<\|startoftext\|><L>Cc1nc(<mask_1:5>ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:5>	3	6	5	-c2	5	Cc1nc(CCOc2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	CCOc2
<\|startoftext\|><L>Cc1nc(-c2ccc([C@H]3CC<mask_1:2>S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:2>	3	21	2	CN(	2	Cc1nc(-c2ccc([C@H]3CCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	N(
<\|startoftext\|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(<mask_1:6>=O)N(C)C)C3)nc2)sc1C<mask_1:6>	0	30	6		6	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)CC(=O)N(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	=O)CC(
<\|startoftext\|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)<mask_1:6>=O)N(C)C)C3)nc2)sc1C<mask_1:6>	1	29	6	(	6	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)C(=O)N(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	(=O)C(
<\|startoftext\|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)<mask_1:7>N(C)C)C3)nc2)sc1C<mask_1:7>	4	29	7	(=O)	7	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)CCCN(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	(=O)CCC
<\|startoftext\|><L>Cc1nc(-c2c<mask_1:4>c([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:4>	1	10	4	c	4	Cc1nc(-c2cc(C)c([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	c(C)
<\|startoftext\|><L>Cc1nc(-c2ccc([C@H]<mask_1:2>CN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:2>	3	18	2	3CC	2	Cc1nc(-c2ccc([C@H]3CCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	3C
<\|startoftext\|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C<mask_1:6>C3)nc2)sc1C<mask_1:6>	1	38	6	)	6	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C(C)C)CC3)nc2)sc1C	Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C	(C)C)C
<\|startoftext\|><L>O=C(O)[C@H]<mask_1:4>CCOc2c(Cl)cccc2Cl)C1<mask_1:4>	5	11	4	1CCN(	4	O=C(O)[C@H]1CN(CCOc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	1CN(
<\|startoftext\|><L>O=C(O)[C<mask_1:4>]1CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:4>	2	8	4	@H	3	O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	@@H
<\|startoftext\|><L>O=C(O)[C<mask_1:3>H]1CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:3>	1	8	3	@	2	O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	@@
<\|startoftext\|><L>O=C(O)<mask_1:4>H]1CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:4>	3	6	4	[C@	4	O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	[C@@
<\|startoftext\|><L>O=C(O)[C@H]1CCN(CC<mask_1:4>Oc2c(Cl)cccc2Cl)C1<mask_1:4>	0	18	4		4	O=C(O)[C@H]1CCN(CC(=O)Oc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	(=O)
<\|startoftext\|><L>O=C(O)[C<mask_1:5>CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:5>	4	8	5	@H]1	5	O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	@@H]1
<\|startoftext\|><L>O=C(O)[C@H]1CC<mask_1:2>N(CCOc2c(Cl)cccc2Cl)C1<mask_1:2>	0	14	2		2	O=C(O)[C@H]1CCCCN(CCOc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	CC
<\|startoftext\|><L>O=C(O)[C@H]1CCN(CC<mask_1:1>(Cl)cccc2Cl)C1<mask_1:1>	4	18	1	Oc2c	1	O=C(O)[C@H]1CCN(CC2(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	2
<\|startoftext\|><L>O=C(O)[C@H]<mask_1:3>CN(CCOc2c(Cl)cccc2Cl)C1<mask_1:3>	2	11	3	1C	3	O=C(O)[C@H]1CCCN(CCOc2c(Cl)cccc2Cl)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	1CC
<\|startoftext\|><L>O=C(O)[C@H]1CCN(CCOc2c(Cl)ccc<mask_1:3>C1<mask_1:3>	5	29	3	c2Cl)	3	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2)C1	O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1	c2)
<\|startoftext\|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(<mask_1:5>nccn3)n2)n1<mask_1:5>	4	28	5	Nc3c	5	Cc1cccc(CN2CCCC[C@@H]2c2csc(NCc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	NCc3c
<\|startoftext\|><L>Cc1cccc(CN2CCCC<mask_1:6>H]2c2csc(Nc3cnccn3)n2)n1<mask_1:6>	4	15	6	[C@@	6	Cc1cccc(CN2CCCCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	CC[C@@
<\|startoftext\|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(N<mask_1:1>c3cnccn3)n2)n1<mask_1:1>	0	29	1		1	Cc1cccc(CN2CCCC[C@@H]2c2csc(NCc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	C
<\|startoftext\|><L>Cc1cc<mask_1:3>N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:3>	4	5	3	cc(C	3	Cc1cccc(N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	cc(
<\|startoftext\|><L>Cc1cccc<mask_1:5>2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:5>	3	7	5	(CN	5	Cc1cccc(OCCN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	(OCCN
<\|startoftext\|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(N<mask_1:5>ccn3)n2)n1<mask_1:5>	4	29	5	c3cn	5	Cc1cccc(CN2CCCC[C@@H]2c2csc(NCc3ccccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	Cc3cc
<\|startoftext\|><L>Cc<mask_1:5>CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:5>	6	2	5	1cccc(	5	Cc1noc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	1noc(
<\|startoftext\|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc<mask_1:6>cn3)n2)n1<mask_1:6>	4	30	6	3cnc	6	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cn(C)cn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	3cn(C)
<\|startoftext\|><L>Cc1cccc(C<mask_1:6>CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:6>	2	9	6	N2	6	Cc1cccc(C(=O)N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	(=O)N2
<\|startoftext\|><L>Cc1cc<mask_1:3>2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:3>	5	5	3	cc(CN	3	Cc1ccn(N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1	n(N
<\|startoftext\|><L>Fc1cccc(CN<mask_1:3>3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:3>	4	10	3	2CCc	3	Fc1cccc(CN2Cc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	2Cc
<\|startoftext\|><L>Fc1cccc(CN2CCc3[nH<mask_1:5>c(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:5>	2	18	5	]n	5	Fc1cccc(CN2CCc3[nH]c(C)c(-c4ccc5c(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	]c(C)
<\|startoftext\|><L>Fc1cccc<mask_1:3>N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:3>	2	7	3	(C	3	Fc1cccc(CCN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	(CC
<\|startoftext\|><L>Fc1cccc(<mask_1:5>CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:5>	0	8	5		5	Fc1cccc(CN(C)CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	CN(C)
<\|startoftext\|><L>Fc1cccc(CN2CCc3[nH]nc(-c<mask_1:5>(c4)OCO5)c3C2)c1<mask_1:5>	6	24	5	4ccc5c	5	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	4ccc5
<\|startoftext\|><L>Fc1c<mask_1:4>c(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:4>	2	4	4	cc	4	Fc1c[nH]c(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	[nH]
<\|startoftext\|><L>Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C<mask_1:5>2)c1<mask_1:5>	0	42	5		5	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C(=S)C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	(=S)C
<\|startoftext\|><L>Fc1cc<mask_1:4>2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:4>	5	5	4	cc(CN	4	Fc1cccc(N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	cc(N
<\|startoftext\|><L>Fc1c<mask_1:3>N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:3>	5	4	3	ccc(C	3	Fc1cnn(N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	nn(
<\|startoftext\|><L>Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2<mask_1:2>)c1<mask_1:2>	0	43	2		2	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2=S)c1	Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1	=S
<\|startoftext\|><L>O=<mask_1:5>NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:5>	2	2	5	C(	5	O=C(NCCNCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	C(NCC
<\|startoftext\|><L>O=C(NC<mask_1:8>Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:8>	0	6	8		8	O=C(NC[C@H](O)Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	[C@H](O)
<\|startoftext\|><L>O=C(NCC<mask_1:4>c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:4>	2	7	4	c1	4	O=C(NCCCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	CCc1
<\|startoftext\|><L>O=C(NCCc1c<mask_1:3>ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:3>	6	10	3	[nH]c2	3	O=C(NCCc1csc2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	sc2
<\|startoftext\|><L>O=C(<mask_1:7>NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:7>	0	4	7		7	O=C(OCC(=O)NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	OCC(=O)
<\|startoftext\|><L>O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)<mask_1:1>)CC2)cc1<mask_1:1>	5	42	1	C3CC3	1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)O)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O
<\|startoftext\|><L>O<mask_1:3>Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:3>	5	1	3	=C(NC	3	O=C(Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	=C(
<\|startoftext\|><L>O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CC<mask_1:5>C(=O)C3CC3)CC2)cc1<mask_1:5>	2	35	5	N(	5	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(CCNC(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	N(CCN
<\|startoftext\|><L>O=C(NC<mask_1:8>]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:8>	7	6	8	Cc1c[nH	8	O=C(NCCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	CCc1c[nH
<\|startoftext\|><L>O=C(NCCc1c[nH]c2ccccc12)c1ccc<mask_1:7>N(C(=O)C3CC3)CC2)cc1<mask_1:7>	6	29	7	(OC2CC	7	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OCC2CCN(C(=O)C3CC3)CC2)cc1	O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1	(OCC2CC
<\|startoftext\|><L>CNc1cc([C@H]2CCCN2C(=O)c2<mask_1:3>3ccc(F)cc3[nH]2)nc(C)n1<mask_1:3>	2	25	3	cc	4	CNc1cc([C@H]2CCCN2C(=O)c2cccc3ccc(F)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	cccc
<\|startoftext\|><L>C<mask_1:1>Nc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:1>	0	1	1		1	CCNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	C
<\|startoftext\|><L>CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)<mask_1:5>C)n1<mask_1:5>	3	43	5	nc(	5	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(COC)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	nc(CO
<\|startoftext\|><L>CNc1cc<mask_1:6>C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:6>	2	6	6	([	6	CNc1cc(CCOC[C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	(CCOC[
<\|startoftext\|><L>CNc1cc([C@H]2CCCN2C(=O)c2c<mask_1:7>c(F)cc3[nH]2)nc(C)n1<mask_1:7>	4	26	7	c3cc	7	CNc1cc([C@H]2CCCN2C(=O)c2cc3c(F)cc(F)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	c3c(F)c
<\|startoftext\|><L>CNc1cc([C@H]2CCCN2C(=O)<mask_1:7>3ccc(F)cc3[nH]2)nc(C)n1<mask_1:7>	4	23	7	c2cc	7	CNc1cc([C@H]2CCCN2C(=O)CCCc2nc3ccc(F)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	CCCc2nc
<\|startoftext\|><L>CNc1cc([C@H]2CCCN2C(=O)c2cc3<mask_1:6>F)cc3[nH]2)nc(C)n1<mask_1:6>	4	28	6	ccc(	6	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(OCF)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	ccc(OC
<\|startoftext\|><L>CNc1cc([C@H]2CCCN2C<mask_1:2>)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:2>	3	19	2	(=O	2	CNc1cc([C@H]2CCCN2C(C)c2cc3ccc(F)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	(C
<\|startoftext\|><L>CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc<mask_1:5>1<mask_1:5>	4	45	5	(C)n	5	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(OC)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	(OC)n
<\|startoftext\|><L>CNc1cc([C@H]2CCCN<mask_1:4>C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:4>	1	17	4	2	4	CNc1cc([C@H]2CCCN2CCNC(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1	2CCN

<|startoftext|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1<mask_1:4>(=O)c1ccoc1C<mask_1:4>

2

30

4

NC

4

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1N(C)(=O)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

N(C)

<|startoftext|><L>Cc1noc(C)c1CO[C@H<mask_1:4>COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:4>

2

17

4

]1

4

Cc1noc(C)c1CO[C@H]1CCCOCC[C@@H]1NC(=O)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

]1CC

<|startoftext|><L>Cc<mask_1:3>C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:3>

5

2

3

1noc(

3

Cc1n(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

1n(

<|startoftext|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)<mask_1:5>1C<mask_1:5>

6

36

5

c1ccoc

6

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1cnoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

c1cnoc

<|startoftext|><L>Cc1noc(C)c1CO[<mask_1:1>H]1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:1>

2

14

1

C@

1

Cc1noc(C)c1CO[CH]1COCC[C@@H]1NC(=O)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

C

<|startoftext|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1<mask_1:4>c1ccoc1C<mask_1:4>

6

30

4

NC(=O)

4

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1N(C)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

N(C)

<|startoftext|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(<mask_1:5>c1ccoc1C<mask_1:5>

3

33

5

=O)

5

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)NCc1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

=O)NC

<|startoftext|><L>Cc1noc(C)c1CO[C@H]1COCC[C@@H]<mask_1:6>(=O)c1ccoc1C<mask_1:6>

3

29

6

1NC

6

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1N(C)C(=O)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

1N(C)C

<|startoftext|><L>Cc1no<mask_1:2>1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:2>

5

2

c(C)c

2

Cc1nonc1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

nc

<|startoftext|><L>Cc1noc(C)c1C<mask_1:4>1COCC[C@@H]1NC(=O)c1ccoc1C<mask_1:4>

6

12

4

O[C@H]

4

Cc1noc(C)c1COCCN1COCC[C@@H]1NC(=O)c1ccoc1C

Cc1noc(C)c1CO[C@H]1COCC[C@@H]1NC(=O)c1ccoc1C

OCCN

<|startoftext|><L>C[C@H](CN[C@H](Cc1ccncc1<mask_1:1>F)F)N1CCOC[C@H]1C<mask_1:1>

6

24

1

)C(F)(

1

C[C@H](CN[C@H](Cc1ccncc1CF)F)N1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

C

<|startoftext|><L>C[C@H](<mask_1:2>CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:2>

0

7

2

C[C@H](CCCN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

CC

<|startoftext|><L>C[<mask_1:5>C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:5>

0

2

5

C[C@H][C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

C@H][

<|startoftext|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1<mask_1:2>CCOC[C@H]1C<mask_1:2>

0

36

2

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCCCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

CC

<|startoftext|><L>C[C@H]<mask_1:3>N[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:3>

2

6

3

(C

3

C[C@H](CCN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

(CC

<|startoftext|><L>C[C@H](CN[C@H](Cc1ccncc1)<mask_1:7>(F)(F)F)N1CCOC[C@H]1C<mask_1:7>

1

25

7

C

7

C[C@H](CN[C@H](Cc1ccncc1)C(=O)CC(F)(F)F)N1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

C(=O)CC

<|startoftext|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F)(F<mask_1:7>COC[C@H]1C<mask_1:7>

6

31

7

)F)N1C

7

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)CN1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

)F)CN1C

<|startoftext|><L>C[C@H](CN[C@H](<mask_1:3>c1)C(F)(F)F)N1CCOC[C@H]1C<mask_1:3>

7

15

3

Cc1ccnc

3

C[C@H](CN[C@H](C1Cc1)C(F)(F)F)N1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

C1C

<|startoftext|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F<mask_1:6>)N1CCOC[C@H]1C<mask_1:6>

5

28

6

)(F)F

5

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

)(F)F

<|startoftext|><L>C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F<mask_1:6>N1CCOC[C@H]1C<mask_1:6>

1

33

6

)

6

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)C(=O)N1CCOC[C@H]1C

C[C@H](CN[C@H](Cc1ccncc1)C(F)(F)F)N1CCOC[C@H]1C

)C(=O)

<|startoftext|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C<mask_1:9>@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:9>

0

36

9

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@@H](C)[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

@@H](C)[C

<|startoftext|><L>CC(C)c1ccc(N2/C(=N\C(=O)<mask_1:8>ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:8>

2

24

8

c3

8

CC(C)c1ccc(N2/C(=N\C(=O)C(=O)Cc3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

C(=O)Cc3

<|startoftext|><L>CC(C)c1c<mask_1:7>C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:7>

6

8

7

cc(N2/

7

CC(C)c1ccc(CN2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

cc(CN2/

<|startoftext|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[<mask_1:6>)cc1<mask_1:6>

7

52

6

C@@H]32

6

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

C@H]32

<|startoftext|><L>CC(C)c1ccc<mask_1:9>N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:9>

7

10

9

(N2/C(=

9

CC(C)c1ccc(N2/C(=N\N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

(N2/C(=N\

<|startoftext|><L>CC(C)c1ccc(N2/C(=N\C<mask_1:5>(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:5>

0

20

5

CC(C)c1ccc(N2/C(=N\C(=O)C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

(=O)C

<|startoftext|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccc<mask_1:1>3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:1>

2

29

1

cc

1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccco3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

o

<|startoftext|><L>CC(C)c1ccc(N2/C(=N\C(=<mask_1:7>cccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:7>

5

22

7

O)c3c

7

CC(C)c1ccc(N2/C(=N\C(=O)COc3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

O)COc3c

<|startoftext|><L>CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3<mask_1:7>@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:7>

4

32

7

)S[C

7

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3Cl)S[C@@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

Cl)S[C@

<|startoftext|><L>CC(C)c1ccc(N2/C(<mask_1:8>C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1<mask_1:8>

3

16

8

=N\

8

CC(C)c1ccc(N2/C(=N\C(=O)C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

CC(C)c1ccc(N2/C(=N\C(=O)c3ccccc3)S[C@H]3CS(=O)(=O)C[C@@H]32)cc1

=N\C(=O)

<|startoftext|><L>CN1CCN(<mask_1:6>=O)[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:6>

2

7

6

C(

6

CN1CCN(CCCNC(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

CCCNC(

<|startoftext|><L>CN1CCN(C(=O)<mask_1:3>[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:3>

0

12

3

CN1CCN(C(=O)NCC[C@H](Sc2ccccc2)c2ccccc2)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

NCC

<|startoftext|><L>CN1CCN(C(=O)[C@H](Sc2ccccc2)c2cc<mask_1:6>)CC1<mask_1:6>

4

32

6

ccc2

6

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2Cl)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

ccc2Cl

<|startoftext|><L>CN1CCN(C(=O<mask_1:5>(Sc2ccccc2)c2ccccc2)CC1<mask_1:5>

6

11

5

)[C@H]

5

CN1CCN(C(=O)C(O)(Sc2ccccc2)c2ccccc2)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

)C(O)

<|startoftext|><L>CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2<mask_1:5>C1<mask_1:5>

2

36

5

)C

5

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)C(O)C1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

)C(O)

<|startoftext|><L>CN1CC<mask_1:4>(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:4>

3

5

4

N(C

4

CN1CCC(NC(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

C(NC

<|startoftext|><L>C<mask_1:1>(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:1>

5

1

N1CCN

1

C1(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

1

<|startoftext|><L>CN1CCN(C(=O<mask_1:6>C@H](Sc2ccccc2)c2ccccc2)CC1<mask_1:6>

2

11

6

)[

6

CN1CCN(C(=O)CCCC[C@H](Sc2ccccc2)c2ccccc2)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

)CCCC[

<|startoftext|><L>CN1CCN(C(=O)[C@H](Sc2cc<mask_1:6>c2)c2ccccc2)CC1<mask_1:6>

2

23

6

cc

6

CN1CCN(C(=O)[C@H](Sc2ccc(Cl)cc2)c2ccccc2)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

c(Cl)c

<|startoftext|><L>CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2<mask_1:6>CC1<mask_1:6>

1

36

6

)

6

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)C(=O)CC1

CN1CCN(C(=O)[C@H](Sc2ccccc2)c2ccccc2)CC1

)C(=O)

<|startoftext|><L>Cc1nc(-c2ccc([C<mask_1:6>]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:6>

2

15

6

@H

6

Cc1nc(-c2ccc([C@H][C@]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

@H][C@

<|startoftext|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=<mask_1:7>(C)C)C3)nc2)sc1C<mask_1:7>

3

31

7

O)N

7

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)CC(C)(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

O)CC(C)

<|startoftext|><L>Cc1nc(<mask_1:5>ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:5>

3

6

5

-c2

5

Cc1nc(CCOc2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

CCOc2

<|startoftext|><L>Cc1nc(-c2ccc([C@H]3CC<mask_1:2>S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:2>

3

21

2

CN(

2

Cc1nc(-c2ccc([C@H]3CCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

N(

<|startoftext|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(<mask_1:6>=O)N(C)C)C3)nc2)sc1C<mask_1:6>

0

30

6

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)CC(=O)N(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

=O)CC(

<|startoftext|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)<mask_1:6>=O)N(C)C)C3)nc2)sc1C<mask_1:6>

1

29

6

(

6

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)C(=O)N(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

(=O)C(

<|startoftext|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)<mask_1:7>N(C)C)C3)nc2)sc1C<mask_1:7>

4

29

7

(=O)

7

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)CCCN(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

(=O)CCC

<|startoftext|><L>Cc1nc(-c2c<mask_1:4>c([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:4>

1

10

4

c

4

Cc1nc(-c2cc(C)c([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

c(C)

<|startoftext|><L>Cc1nc(-c2ccc([C@H]<mask_1:2>CN(S(=O)(=O)N(C)C)C3)nc2)sc1C<mask_1:2>

3

18

2

3CC

2

Cc1nc(-c2ccc([C@H]3CCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

3C

<|startoftext|><L>Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C<mask_1:6>C3)nc2)sc1C<mask_1:6>

1

38

6

)

6

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C(C)C)CC3)nc2)sc1C

Cc1nc(-c2ccc([C@H]3CCCN(S(=O)(=O)N(C)C)C3)nc2)sc1C

(C)C)C

<|startoftext|><L>O=C(O)[C@H]<mask_1:4>CCOc2c(Cl)cccc2Cl)C1<mask_1:4>

5

11

4

1CCN(

4

O=C(O)[C@H]1CN(CCOc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

1CN(

<|startoftext|><L>O=C(O)[C<mask_1:4>]1CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:4>

2

8

4

@H

3

O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

@@H

<|startoftext|><L>O=C(O)[C<mask_1:3>H]1CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:3>

1

8

3

@

2

O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

@@

<|startoftext|><L>O=C(O)<mask_1:4>H]1CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:4>

3

6

4

[C@

4

O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

[C@@

<|startoftext|><L>O=C(O)[C@H]1CCN(CC<mask_1:4>Oc2c(Cl)cccc2Cl)C1<mask_1:4>

0

18

4

O=C(O)[C@H]1CCN(CC(=O)Oc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

(=O)

<|startoftext|><L>O=C(O)[C<mask_1:5>CCN(CCOc2c(Cl)cccc2Cl)C1<mask_1:5>

4

8

5

@H]1

5

O=C(O)[C@@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

@@H]1

<|startoftext|><L>O=C(O)[C@H]1CC<mask_1:2>N(CCOc2c(Cl)cccc2Cl)C1<mask_1:2>

0

14

2

O=C(O)[C@H]1CCCCN(CCOc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

CC

<|startoftext|><L>O=C(O)[C@H]1CCN(CC<mask_1:1>(Cl)cccc2Cl)C1<mask_1:1>

4

18

1

Oc2c

1

O=C(O)[C@H]1CCN(CC2(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

2

<|startoftext|><L>O=C(O)[C@H]<mask_1:3>CN(CCOc2c(Cl)cccc2Cl)C1<mask_1:3>

2

11

3

1C

3

O=C(O)[C@H]1CCCN(CCOc2c(Cl)cccc2Cl)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

1CC

<|startoftext|><L>O=C(O)[C@H]1CCN(CCOc2c(Cl)ccc<mask_1:3>C1<mask_1:3>

5

29

3

c2Cl)

3

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2)C1

O=C(O)[C@H]1CCN(CCOc2c(Cl)cccc2Cl)C1

c2)

<|startoftext|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(<mask_1:5>nccn3)n2)n1<mask_1:5>

4

28

5

Nc3c

5

Cc1cccc(CN2CCCC[C@@H]2c2csc(NCc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

NCc3c

<|startoftext|><L>Cc1cccc(CN2CCCC<mask_1:6>H]2c2csc(Nc3cnccn3)n2)n1<mask_1:6>

4

15

6

[C@@

6

Cc1cccc(CN2CCCCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

CC[C@@

<|startoftext|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(N<mask_1:1>c3cnccn3)n2)n1<mask_1:1>

0

29

1

Cc1cccc(CN2CCCC[C@@H]2c2csc(NCc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

C

<|startoftext|><L>Cc1cc<mask_1:3>N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:3>

4

5

3

cc(C

3

Cc1cccc(N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

cc(

<|startoftext|><L>Cc1cccc<mask_1:5>2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:5>

3

7

5

(CN

5

Cc1cccc(OCCN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

(OCCN

<|startoftext|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(N<mask_1:5>ccn3)n2)n1<mask_1:5>

4

29

5

c3cn

5

Cc1cccc(CN2CCCC[C@@H]2c2csc(NCc3ccccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

Cc3cc

<|startoftext|><L>Cc<mask_1:5>CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:5>

6

2

5

1cccc(

5

Cc1noc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

1noc(

<|startoftext|><L>Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc<mask_1:6>cn3)n2)n1<mask_1:6>

4

30

6

3cnc

6

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cn(C)cn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

3cn(C)

<|startoftext|><L>Cc1cccc(C<mask_1:6>CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:6>

2

9

6

N2

6

Cc1cccc(C(=O)N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

(=O)N2

<|startoftext|><L>Cc1cc<mask_1:3>2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1<mask_1:3>

5

3

cc(CN

3

Cc1ccn(N2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

Cc1cccc(CN2CCCC[C@@H]2c2csc(Nc3cnccn3)n2)n1

n(N

<|startoftext|><L>Fc1cccc(CN<mask_1:3>3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:3>

4

10

3

2CCc

3

Fc1cccc(CN2Cc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

2Cc

<|startoftext|><L>Fc1cccc(CN2CCc3[nH<mask_1:5>c(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:5>

2

18

5

]n

5

Fc1cccc(CN2CCc3[nH]c(C)c(-c4ccc5c(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

]c(C)

<|startoftext|><L>Fc1cccc<mask_1:3>N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:3>

2

7

3

(C

3

Fc1cccc(CCN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

(CC

<|startoftext|><L>Fc1cccc(<mask_1:5>CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:5>

0

8

5

Fc1cccc(CN(C)CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

CN(C)

<|startoftext|><L>Fc1cccc(CN2CCc3[nH]nc(-c<mask_1:5>(c4)OCO5)c3C2)c1<mask_1:5>

6

24

5

4ccc5c

5

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

4ccc5

<|startoftext|><L>Fc1c<mask_1:4>c(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:4>

2

4

cc

4

Fc1c[nH]c(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

[nH]

<|startoftext|><L>Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C<mask_1:5>2)c1<mask_1:5>

0

42

5

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C(=S)C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

(=S)C

<|startoftext|><L>Fc1cc<mask_1:4>2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:4>

5

4

cc(CN

4

Fc1cccc(N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

cc(N

<|startoftext|><L>Fc1c<mask_1:3>N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1<mask_1:3>

5

4

3

ccc(C

3

Fc1cnn(N2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

nn(

<|startoftext|><L>Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2<mask_1:2>)c1<mask_1:2>

0

43

2

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2=S)c1

Fc1cccc(CN2CCc3[nH]nc(-c4ccc5c(c4)OCO5)c3C2)c1

=S

<|startoftext|><L>O=<mask_1:5>NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:5>

2

5

C(

5

O=C(NCCNCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

C(NCC

<|startoftext|><L>O=C(NC<mask_1:8>Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:8>

0

6

8

O=C(NC[C@H](O)Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

[C@H](O)

<|startoftext|><L>O=C(NCC<mask_1:4>c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:4>

2

7

4

c1

4

O=C(NCCCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

CCc1

<|startoftext|><L>O=C(NCCc1c<mask_1:3>ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:3>

6

10

3

[nH]c2

3

O=C(NCCc1csc2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

sc2

<|startoftext|><L>O=C(<mask_1:7>NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:7>

0

4

7

O=C(OCC(=O)NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

OCC(=O)

<|startoftext|><L>O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)<mask_1:1>)CC2)cc1<mask_1:1>

5

42

1

C3CC3

1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)O)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O

<|startoftext|><L>O<mask_1:3>Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:3>

5

1

3

=C(NC

3

O=C(Cc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

=C(

<|startoftext|><L>O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CC<mask_1:5>C(=O)C3CC3)CC2)cc1<mask_1:5>

2

35

5

N(

5

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(CCNC(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

N(CCN

<|startoftext|><L>O=C(NC<mask_1:8>]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1<mask_1:8>

7

6

8

Cc1c[nH

8

O=C(NCCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

CCc1c[nH

<|startoftext|><L>O=C(NCCc1c[nH]c2ccccc12)c1ccc<mask_1:7>N(C(=O)C3CC3)CC2)cc1<mask_1:7>

6

29

7

(OC2CC

7

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OCC2CCN(C(=O)C3CC3)CC2)cc1

O=C(NCCc1c[nH]c2ccccc12)c1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1

(OCC2CC

<|startoftext|><L>CNc1cc([C@H]2CCCN2C(=O)c2<mask_1:3>3ccc(F)cc3[nH]2)nc(C)n1<mask_1:3>

2

25

3

cc

4

CNc1cc([C@H]2CCCN2C(=O)c2cccc3ccc(F)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

cccc

<|startoftext|><L>C<mask_1:1>Nc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:1>

0

1

CCNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

C

<|startoftext|><L>CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)<mask_1:5>C)n1<mask_1:5>

3

43

5

nc(

5

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(COC)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

nc(CO

<|startoftext|><L>CNc1cc<mask_1:6>C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:6>

2

6

([

6

CNc1cc(CCOC[C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

(CCOC[

<|startoftext|><L>CNc1cc([C@H]2CCCN2C(=O)c2c<mask_1:7>c(F)cc3[nH]2)nc(C)n1<mask_1:7>

4

26

7

c3cc

7

CNc1cc([C@H]2CCCN2C(=O)c2cc3c(F)cc(F)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

c3c(F)c

<|startoftext|><L>CNc1cc([C@H]2CCCN2C(=O)<mask_1:7>3ccc(F)cc3[nH]2)nc(C)n1<mask_1:7>

4

23

7

c2cc

7

CNc1cc([C@H]2CCCN2C(=O)CCCc2nc3ccc(F)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

CCCc2nc

<|startoftext|><L>CNc1cc([C@H]2CCCN2C(=O)c2cc3<mask_1:6>F)cc3[nH]2)nc(C)n1<mask_1:6>

4

28

6

ccc(

6

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(OCF)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

ccc(OC

<|startoftext|><L>CNc1cc([C@H]2CCCN2C<mask_1:2>)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:2>

3

19

2

(=O

2

CNc1cc([C@H]2CCCN2C(C)c2cc3ccc(F)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

(C

<|startoftext|><L>CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc<mask_1:5>1<mask_1:5>

4

45

5

(C)n

5

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(OC)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

(OC)n

<|startoftext|><L>CNc1cc([C@H]2CCCN<mask_1:4>C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1<mask_1:4>

1

17

4

2

4

CNc1cc([C@H]2CCCN2CCNC(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

CNc1cc([C@H]2CCCN2C(=O)c2cc3ccc(F)cc3[nH]2)nc(C)n1

2CCN