My deep learning rig (2022)
I have pretty much the same setup but just 4 3080s in one machine. If you go to rent something from vast.ai, you can see the hardware specs of the most performant machines.  I just copied those and pieced together the rest.  Learning about PCIe versions and ports was very interesting, as I thought I could use another motherboard for a similar purpose, but just because there are four PCIe 3 slots, it doesn't mean they're all usable at 16x AT THE SAME TIME!<p>I bought 21 R12 Aurora Alienwares and turned a side-office in my garage into a hot-ass crypto farm with two swamp coolers, four 20A circuits, a 15A circuit, and a bunch of surge protectors.  I was always afraid to move something in fear that I'd overload a circuit due to the effort in calculating which power supply was powering which machine(s).<p>I gave away the 3080s to friends and family and kept the 6 3090s.