Haemophilia A trial results 'mind-blowing'
There is a pretty strong argument that Haemophilia is the disease that has had the biggest impact on the last 100 years.  Russian heir to the throne Alexis Romanov inherited the disease and his suffering and lack of treatment options destabilized his family and contributed to leadership issues culminating in Russian defeat in WW1 and the Russian revolution and the rise of the Soviet Union.<p>Agree?  If not, what disease led to a greater string of consequences?  Malaria, Spanish Influenza, polio, AIDS?