Significant breakthrough in search for Parkinson's biomarker
I just found out about Thiamine (vitamin B1) megadose therapy for Parkinson's:<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762356/" rel="nofollow">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762356/</a><p>Another study: <a href="https://pubmed.ncbi.nlm.nih.gov/26505466/" rel="nofollow">https://pubmed.ncbi.nlm.nih.gov/26505466/</a><p>> Conclusions: Administration of parenteral high-dose thiamine was effective in reversing PD motor and nonmotor symptoms. The clinical improvement was stable over time in all the patients. From our clinical evidence, we hypothesize that a dysfunction of thiamine-dependent metabolic processes could cause selective neural damage in the centers typically affected by this disease and might be a fundamental molecular event provoking neurodegeneration. Thiamine could have both restorative and neuroprotective action in PD.<p>This experience report of halting Parkinson's: <a href="https://youtu.be/iuSOQOTyB9w" rel="nofollow">https://youtu.be/iuSOQOTyB9w</a>