The death of corporate research labs
Holdup. Lack of anti-trust enforcement is blamed (among other things) for the end of corporate R&D, but Monopoly breakup is exactly what killed Bell labs! 9 smaller companies weren't going to fund their own lab, and the only reason the lab existed was to find new markets to explore.
In fact, nearly all of the examples of successful R&D labs came from corporations that so dominated their industry they put money into finding new investments: Xerox. Kodak Eastmann. Google might meet this definition.<p>I think we also overrate the significance of the corporate labs. There are not a lot of successful examples where the host company actually profited from the invention. Just a lot that bungled them or prematurely killed them (like when AT&T almost invented the internet). Or snuck out accidentally (like the Xerox Alto).