Deck.js: A JavaScript library for building modern HTML presentations. 
I really like the aesthetics but as mentioned here it's not portable / shareable offline.
In addition - more than the fact that you need a modern browser (which is ok, really), you need a modern projector for such a resolution, and this is nothing you can just download and install.<p>Nothing is more awkward than displaying such a presentation on a backwards projector which cuts it off.<p>I use this regularily, which solves both problems:
<a href="https://github.com/geraldb/slideshow" rel="nofollow">https://github.com/geraldb/slideshow</a><p>I plan to use this from now on, since it has nicer UI:
<a href="https://github.com/juliocesar/shining" rel="nofollow">https://github.com/juliocesar/shining</a><p>For deck.js to be perfect it<p>- needs to understand markdown<p>- needs to use precent (%) scaling so it could scale   resolutions easily<p>- export to an offline format.<p>All in all it has astonishing UI effects which makes me want to use it.