Crohn’s Disease: Is the Cold Chain Hypothesis Still Hot?
I have crohns disease.<p>Many people with my disease report improvement or even remission with specialized diets, but what&#x27;s interesting is how disjoint these diets are. Some people eat only meat, others only vegan, others high-fiber, others low-fiber, and so on.<p>The only similarity I can draw between these diets is that they greatly restrict the variety of food eaten. It makes me wonder if the modern practice of eating a variety of foods is harmful to our gut biome. I reckon variety results in constantly changing bacteria bloom&#x2F;die-off scenarios. The blooms cause immune response flare-ups and accelerate bacterial evolution, while the die-offs cause extinctions, reducing the variety of our gut biomes.<p>Anyway, this is just an armchair hypothesis, but I&#x27;m curious to hear if anyone has thoughts on it. I note that it fits the story of Crohns being a modern &quot;first-world&quot; disease, as for most of history humans ate the same few foods everyday, just as animals do.<p>tl;dr: eating everything in moderation may be terrible advice