Eating in 10-hour window can override disease-causing genetic defects
I&#x27;ve been on an intermittent fasting schedule (I usually do 16&#x2F;8) for about a year and a half. I lost some weight during the first several months, but have leveled off to a reasonable weight (which is probably 10 pounds heavier than I&#x27;d like, but ~25 pounds lighter than when I started intermittent fasting).<p>Overall, I don&#x27;t see any dramatic changes. Lots of people claim to see a significant difference, usually positive, in energy, strength, mood, sleep, etc. But, I generally think all of those metrics are &quot;about the same&quot; for me. Maybe I&#x27;m mildly more energetic because of carrying less weight around. But, I&#x27;m also at the age where the effects of aging begin to be noticeable...so, maybe just maintaining levels is progress?<p>Nonetheless, after several years of research into the topic, and related topics like caloric restriction, a couple of years ago I was convinced that the evidence was compelling enough to make it part of my life and started reducing my eating period each day until I was comfortable with 16 hours of fasting each day (sometimes I&#x27;ll do 20 or 24, if I&#x27;m busy and feel OK). I recommend it to people who ask about it, but not because it&#x27;s a magical cure for all that ails you. I just think the evidence is strong enough to be worth the minor trade-offs. It isn&#x27;t a risky decision (with the caveat that it probably isn&#x27;t appropriate for people with diabetes or hypoglycemia or similar)...none of the science indicates negative results, and nearly all of it indicates positive results to one degree or another. It&#x27;s pretty much like any other diet decision, e.g. eat more vegetables because you&#x27;ll probably live longer, not because it&#x27;ll cure cancer or make you an Olympic athlete.