Is the Alzheimer's “Amyloid Hypothesis” Wrong? (2017)
This comment from two months ago (when Carl Kasell died) was very interesting:<p><i>it is not for want of trying. Eli Lily bet the farm and lost, and they aren’t alone.</i>
<i>At this point, we’re beginning to think previously unthinkable thoughts like “what if the hypothesis the last 20 years of research was based on (beta amyloid plaques)is just totally wrong”.</i><p><i>we’ve made drugs that reduce plaques. they don’t ameliorate the disease.</i><p><a href="https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=16863945" rel="nofollow">https:&#x2F;&#x2F;news.ycombinator.com&#x2F;item?id=16863945</a>