Bidirectional genetic overlap between bipolar disorder and intelligence
Not a finding of this particular study but I found this bit in the “Background” section interesting. It was hard for me to understand at first:<p>&gt; <i>In addition, a large-scale prospective epidemiological study of more than one million Swedish men found a “reversed–J” shaped association between intelligence and hospitalization for BD (the average follow-up period was 22.6 years, and the patients had no psychiatric comorbidities) [17]. Specifically, they found that the risk of hospitalization with any form of BD decreased as the intelligence increased; in the meantime, subjects with either the lowest IQ scores or the highest IQ scores (especially those who performed better in verbal or technical tests) had greater risk of hospitalization with pure BD [17].</i><p>because I’d never heard of “pure” vs mixed BPD before. I have a sibling who seems to be pure manic&#x2F;hypomanic BPD, with high IQ, which according to this study seems to doom them to being hospitalized frequently; something that has tracked for the past few years since they were diagnosed.<p>Does anyone know of any research specific to sufferers of pure (manic) BPD, and how we can help them stick to treatment and medication?