The biological basis for sex differences in autoimmune diseases
It seems that in general female <i>immune</i> system is stronger. While &quot;man flu&quot; is a popular term for men getting excuses to complain and play on a computer during a minor infection - it might have a grain of truth. For example, COVID male death rates are higher than female (for the same age). See <a href="https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41467-020-19741-6" rel="nofollow">https:&#x2F;&#x2F;www.nature.com&#x2F;articles&#x2F;s41467-020-19741-6</a> and <a href="https:&#x2F;&#x2F;www.thelancet.com&#x2F;journals&#x2F;langlo&#x2F;article&#x2F;PIIS2214-109X(20)30464-2&#x2F;fulltext" rel="nofollow">https:&#x2F;&#x2F;www.thelancet.com&#x2F;journals&#x2F;langlo&#x2F;article&#x2F;PIIS2214-1...</a>.<p>Of course, a stronger immune system is NOT a universal advantage, as it can backfire. (There is a similar phenomena in other systems, e.g. military.)