clinicalnlplab/NovelTax · Datasets at Hugging Face

27,792,736

The co-administration of micronized magnesium organic salts with opioids increased their synergetic analgesic effect. This may suggest an innovative approach to the treatment of pain in clinical practice.

null

Method and Material Novelty - 2.2 New application method - 2.2.1 New Therapy

2/3/2025, 2:10:58 PM

openai

null

Method and Material Novelty - 2.2 New application method - 2.2.1 New Therapy

{ "category": "2 Method and Material Novelty - 2.2 New application method - 2.2.1 New Therapy", "reason": "The conclusion suggests an innovative approach to pain treatment by co-administering micronized magnesium organic salts with opioids, indicating a novel therapeutic strategy in clinical practice. The use of 'innovative approach' directly refers to their novel contribution in therapy." }

The conclusion suggests an innovative approach to pain treatment by co-administering micronized magnesium organic salts with opioids, indicating a novel therapeutic strategy in clinical practice. The use of 'innovative approach' directly refers to their novel contribution in therapy.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

15,291,097

Five cDNA sequences were found PTS related. 3 of them may represent the genes that are either identical or nearly identical to previously reported genes The other 2 sequences are most probably new sequences not existing in GenBank DNA database, which have been registered in the GenBank DNA database as new sequences.

null

Finding Novelty - 3.1 New object - 3.1.2 New sequence

2/3/2025, 2:11:24 PM

openai

null

Finding Novelty - 3.1 New object - 3.1.2 New sequence

{ "category": "3 Finding Novelty - 3.1 New object - 3.1.2 New sequence", "reason": "The text mentions the discovery of two cDNA sequences that are most probably new and not existing in the GenBank DNA database. This indicates the identification of new nucleotide sequences, which falls under the category of discovering a new object, specifically new sequences." }

The text mentions the discovery of two cDNA sequences that are most probably new and not existing in the GenBank DNA database. This indicates the identification of new nucleotide sequences, which falls under the category of discovering a new object, specifically new sequences.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

20,961,436

Based on the representative sample, the QADS factor structure was revised. Gender-specific standard percentages permit a population-based assessment of individual disgust sensitivity. The differences of the original QADS, the new solution, and the Disgust Scale - Revised will be discussed.

null

Not Novelty

2/3/2025, 2:11:43 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text does not explicitly claim novelty in terms of introducing new concepts, methods, or findings. It discusses revisions and comparisons of existing scales, which does not meet the criteria for novelty as per the specified taxonomy." }

The text does not explicitly claim novelty in terms of introducing new concepts, methods, or findings. It discusses revisions and comparisons of existing scales, which does not meet the criteria for novelty as per the specified taxonomy.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

15,724,636

Transoesophageal three-dimensional echocardiography facilitates quantitative analysis of aortic wall stiffness and regional beta-index measurements. The local variability of beta-index is correlated with intima-media thickness, whereas the correlation with the thickness of atherosclerotic plaques is not statistically significant. These measurements may be of importance in the assessment of the degree of atherosclerosis advancement. It forms new perspectives in diagnostics with the ability to evaluate the influence of pharmacotherapy and life-style modifications.

null

Concept Novelty - 1.2 New perspective

2/3/2025, 2:11:49 PM

openai

null

Concept Novelty - 1.2 New perspective

{ "category": "1 Concept Novelty - 1.2 New perspective", "reason": "The conclusion mentions that the study 'forms new perspectives in diagnostics,' indicating a fresh subjective perspective or unique way of interpreting the objective findings. This aligns with the 'New perspective' sub-label under 'Concept Novelty.' The text does not introduce a new method, object, or finding, but rather offers a new way of looking at existing diagnostic processes." }

The conclusion mentions that the study 'forms new perspectives in diagnostics,' indicating a fresh subjective perspective or unique way of interpreting the objective findings. This aligns with the 'New perspective' sub-label under 'Concept Novelty.' The text does not introduce a new method, object, or finding, but rather offers a new way of looking at existing diagnostic processes.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

31,315,682

This is the second case of isolated congenital intercostal pulmonary hernia reported in the French and English literature. It is the first to be treated by thoracoscopy. Based on this case we performed a review of the diagnosis and therapeutic aspect of pulmonary hernias.

null

Finding Novelty - 3.1 New object - 3.1.6 New case

2/3/2025, 2:12:23 PM

openai

null

Finding Novelty - 3.1 New object - 3.1.6 New case

{ "category": "3 Finding Novelty - 3.1 New object - 3.1.6 New case", "reason": "The text mentions that this is the second case of isolated congenital intercostal pulmonary hernia reported, indicating a new case. Additionally, it is the first to be treated by thoracoscopy, which highlights a novel aspect of treatment for this specific case." }

The text mentions that this is the second case of isolated congenital intercostal pulmonary hernia reported, indicating a new case. Additionally, it is the first to be treated by thoracoscopy, which highlights a novel aspect of treatment for this specific case.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

34,722,763

Our study suggests that understanding the miRNA-mRNA interactions will provide insights into the epilepsy pathogenesis. In addition, our results indicate that miR-484 may be a promising novel biomarker for TLE.

null

Finding Novelty - 3.2 New property/feature - 3.2.3 New marker

2/3/2025, 2:13:07 PM

openai

null

Finding Novelty - 3.2 New property/feature - 3.2.3 New marker

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.3 New marker", "reason": "The conclusion mentions that miR-484 may be a promising novel biomarker for TLE, which indicates the discovery of a new biological marker. This aligns with the classification of a new property/feature, specifically a new marker, as it identifies a new attribute of an existing object (miR-484) in the context of TLE." }

The conclusion mentions that miR-484 may be a promising novel biomarker for TLE, which indicates the discovery of a new biological marker. This aligns with the classification of a new property/feature, specifically a new marker, as it identifies a new attribute of an existing object (miR-484) in the context of TLE.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

16,995,422

The improvement of the diagnostics of latent tuberculosis infection can bring the routine introduction of new tests, e.g. Quantiferon-TB Gold or other methods.

null

Not Novelty

2/3/2025, 2:13:15 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence discusses the potential improvement in diagnostics through the introduction of new tests, but it does not claim any novel contribution by the authors themselves. It mentions existing tests like Quantiferon-TB Gold, which are not new developments by the authors. Therefore, it does not meet the criteria for novelty classification." }

The sentence discusses the potential improvement in diagnostics through the introduction of new tests, but it does not claim any novel contribution by the authors themselves. It mentions existing tests like Quantiferon-TB Gold, which are not new developments by the authors. Therefore, it does not meet the criteria for novelty classification.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

36,550,818

To sum up, this review will assess the effectiveness and safety of scalp acupuncture for the treatment of migraine. The results of this review are expected to provide new guidelines for the treatment of migraine.

null

Not Novelty

2/3/2025, 2:13:50 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text is a summary of a review paper, which aims to assess existing knowledge on the effectiveness and safety of scalp acupuncture for migraine treatment. Although it mentions 'new guidelines,' this does not indicate the introduction of novel research findings, methods, or concepts by the authors themselves. Instead, it suggests that the review might lead to updated recommendations based on existing evidence. Therefore, it does not meet the criteria for novelty as defined in the taxonomy." }

The text is a summary of a review paper, which aims to assess existing knowledge on the effectiveness and safety of scalp acupuncture for migraine treatment. Although it mentions 'new guidelines,' this does not indicate the introduction of novel research findings, methods, or concepts by the authors themselves. Instead, it suggests that the review might lead to updated recommendations based on existing evidence. Therefore, it does not meet the criteria for novelty as defined in the taxonomy.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

36,453,878

BBOX1-AS1 facilitated the EC development and malignancy via miR-361-3p/COL1A1 axis, indicating BBOX1-AS1 could be a novel therapy target for the diagnostic of EC.

null

New target

2/3/2025, 2:13:57 PM

openai

null

New target

{ "category": "3.2.6 New target", "reason": "The sentence identifies BBOX1-AS1 as a novel therapy target for the diagnostic of EC, which falls under the category of discovering a new molecular or cellular target for therapeutic intervention. The use of 'novel therapy target' indicates the identification of a new target, which is a new property/feature of an existing object." }

The sentence identifies BBOX1-AS1 as a novel therapy target for the diagnostic of EC, which falls under the category of discovering a new molecular or cellular target for therapeutic intervention. The use of 'novel therapy target' indicates the identification of a new target, which is a new property/feature of an existing object.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,704,969

This is the first meta-analysis conducted in Asian investigating the correlation between XRCC1 polymorphisms and susceptibility to bladder cancer. Our meta-analysis shows that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with a significantly increased risk of bladder cancer in Asian population.

null

Concept Novelty - New attempt

2/3/2025, 2:14:30 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The text explicitly claims novelty by stating 'This is the first meta-analysis conducted in Asian,' indicating that this is a new attempt to investigate the correlation between XRCC1 polymorphisms and susceptibility to bladder cancer in this specific population." }

The text explicitly claims novelty by stating 'This is the first meta-analysis conducted in Asian,' indicating that this is a new attempt to investigate the correlation between XRCC1 polymorphisms and susceptibility to bladder cancer in this specific population.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

12,934,124

First-generation antipsychotics do not appear to be teratogenic. If antipsychotics are used in the third trimester, the neonate should be observed for extrapyramidal symptoms. When the use of a first-generation antipsychotic is indicated in a lactating woman, the favourable effects of lactation will most likely in the majority of cases exceed the theoretical risk of detrimental drug effects in the infant. Nevertheless, efforts should always be made to minimise drug exposure to the fetus or suckling infant.

null

Not Novelty

2/3/2025, 2:14:36 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not contain any explicit claims of novelty or new contributions by the authors. It summarizes existing knowledge and provides recommendations based on current understanding, without introducing new ideas, methods, or findings. There are no strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions." }

The provided text does not contain any explicit claims of novelty or new contributions by the authors. It summarizes existing knowledge and provides recommendations based on current understanding, without introducing new ideas, methods, or findings. There are no strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

17,939,881

The retrospective nature of the study meant that the findings may be susceptible to missing or lost data. The results obtained here represent individuals enrolled in private healthcare plans and may not, therefore, be representative of the entire US population. The lack of a virologic diagnosis of influenza, and an index date based on the first diagnosis of influenza rather than first exposure or symptom onset, may have resulted in a conservative estimate of treatment effect. Secondary complications of influenza, such as respiratory disease and otitis media, were reduced in patients treated with oseltamivir. The risk of hospitalization for respiratory diseases was not reduced, although there was a reduction in the risk of hospitalization for any reason. Clinical benefits observed with oseltamivir were not associated with a change in healthcare costs.

null

Not Novelty

2/3/2025, 2:14:43 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion does not introduce any novel ideas, methods, or findings. It summarizes the results of the study, discusses limitations, and provides observations about the effects of oseltamivir without claiming any new or first-time discoveries. There are no explicit claims of novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the study's contributions." }

The conclusion does not introduce any novel ideas, methods, or findings. It summarizes the results of the study, discusses limitations, and provides observations about the effects of oseltamivir without claiming any new or first-time discoveries. There are no explicit claims of novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the study's contributions.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

35,964,045

To our knowledge, this is the first trial studying not only the effect but also the cost-effectiveness of alarm interventions as commonly added in urotherapy.

null

Concept Novelty - 1.1 New attempt

2/3/2025, 2:14:48 PM

openai

null

Concept Novelty - 1.1 New attempt

{ "category": "1 Concept Novelty - 1.1 New attempt", "reason": "The sentence explicitly claims novelty by stating 'this is the first trial' which indicates a new attempt in studying both the effect and cost-effectiveness of alarm interventions in urotherapy. This aligns with the 'New attempt' sub-label under 'Concept Novelty' as it explores a new scientific research content that has not been explored before." }

The sentence explicitly claims novelty by stating 'this is the first trial' which indicates a new attempt in studying both the effect and cost-effectiveness of alarm interventions in urotherapy. This aligns with the 'New attempt' sub-label under 'Concept Novelty' as it explores a new scientific research content that has not been explored before.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

15,843,830

Cigarettes, unregulated, are unduly dangerous. Though many smoke toxicants cannot yet be quantified, risk assessment based on current data suggests that regulation could partly reduce identifiable cancer risk, and possibly eliminate the excess cardiovascular and respiratory toxicity of HEM, when compared with regular Canadian brands. The first goal should be to reduce emissions of the leading three toxicants, in addition to more effective charcoal filters. Tobacco smoke, unlike unburnt or non-smoking tobacco, contains toxic gases and trillions of reactive oxygen species molecules per puff, and will remain inherently harmful. Regulation could usefully part-reduce smoke toxicity exposure for continuing smokers, while not relenting on efforts to assist smokers and society to be quit of smoking.

null

Not Novelty

2/3/2025, 2:14:54 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion discusses the potential benefits of regulating cigarette emissions and reducing smoke toxicity exposure. Although it mentions 'the first goal,' it does not claim any novel research findings, methods, or concepts introduced by the authors. The text primarily summarizes existing knowledge and suggests regulatory actions, which does not meet the criteria for novelty classification." }

The conclusion discusses the potential benefits of regulating cigarette emissions and reducing smoke toxicity exposure. Although it mentions 'the first goal,' it does not claim any novel research findings, methods, or concepts introduced by the authors. The text primarily summarizes existing knowledge and suggests regulatory actions, which does not meet the criteria for novelty classification.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

24,570,114

We did not find any RCTs that compared first-line beta-blockers with other first-line antihypertensive medications for the treatment of chronic type B TAD. Therefore, there is no RCT evidence to support the current guidelines recommending the use of beta-blockers. RCTs are required to assess the benefits and harms of beta-blockers and other antihypertensive medications as first-line treatment of chronic type B TAD.

null

Not Novelty

2/3/2025, 2:14:59 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text does not introduce any novel ideas, methods, or findings. It highlights the absence of RCTs comparing beta-blockers with other antihypertensive medications for chronic type B TAD and calls for future research. There is no mention of new or first contributions by the authors themselves." }

The text does not introduce any novel ideas, methods, or findings. It highlights the absence of RCTs comparing beta-blockers with other antihypertensive medications for chronic type B TAD and calls for future research. There is no mention of new or first contributions by the authors themselves.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

22,870,226

The ability to generate and characterize hundreds of thousands of affinity-selected peptides creates an effective means towards the interrogation of the IgOme and understanding of the humoral response to disease. Deep Panning should open the door to new possibilities for serological diagnostics, vaccine design and the discovery of the correlates of immunity to emerging infectious agents.

null

Not Novelty

2/3/2025, 2:15:04 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text discusses potential applications and implications of a method called Deep Panning, suggesting it could lead to new possibilities in diagnostics and vaccine design. However, it does not explicitly claim that the method itself is novel or that the study presents new findings. The mention of 'new possibilities' refers to future applications rather than a novel contribution in the current research." }

The text discusses potential applications and implications of a method called Deep Panning, suggesting it could lead to new possibilities in diagnostics and vaccine design. However, it does not explicitly claim that the method itself is novel or that the study presents new findings. The mention of 'new possibilities' refers to future applications rather than a novel contribution in the current research.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

34,185,039

Tackling homelessness in these ways highlighted resistant structural problems, notably how to ensure sufficient affordable housing. Plans to prevent homelessness must address such problems. This new approach marks a cultural change in multi-agency services support for homeless people. The challenge is to sustain these improvements, and learn lessons for the future.

null

Other new application method

2/3/2025, 2:15:35 PM

openai

null

Other new application method

{ "category": "2.2.5 Other new application method", "reason": "The text mentions a 'new approach' which marks a cultural change in multi-agency services support for homeless people. This suggests a novel application method in addressing homelessness, indicating a new way of combining existing knowledge or methods to form an innovative approach. It does not introduce a new concept, method, or finding in the biomedical sense, but rather a new application method in social services." }

The text mentions a 'new approach' which marks a cultural change in multi-agency services support for homeless people. This suggests a novel application method in addressing homelessness, indicating a new way of combining existing knowledge or methods to form an innovative approach. It does not introduce a new concept, method, or finding in the biomedical sense, but rather a new application method in social services.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

15,613,668

AEP occurred at an increased rate among this deployed military population and resulted in 2 deaths. Failure to consider AEP in the differential diagnosis of respiratory failure in military personnel can result in missing this syndrome and possibly death. The etiology of AEP remains unclear, but the association with new-onset smoking suggests a possible link.

null

Not novelty

2/3/2025, 2:15:48 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The provided text does not introduce any novel ideas, methods, or findings. It summarizes existing knowledge about the increased rate of AEP in a specific population and suggests a possible link with new-onset smoking, but it does not claim any new discovery or innovation by the authors. There are no strong indicators of novelty such as 'first,' 'novel,' 'innovation,' or 'new' referring to the authors' contributions." }

The provided text does not introduce any novel ideas, methods, or findings. It summarizes existing knowledge about the increased rate of AEP in a specific population and suggests a possible link with new-onset smoking, but it does not claim any new discovery or innovation by the authors. There are no strong indicators of novelty such as 'first,' 'novel,' 'innovation,' or 'new' referring to the authors' contributions.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

19,956,550

The in vivo and in vitro findings clearly indicate the development of immunogenicity in NSPCs following progressive JEV infection, in our case, JEV infection. Following a neurotropic virus infection, NSPCs possibly behave as immunogenic cells and contribute to both the innate and adaptive immune axes. The newly discovered immunological properties of NSPCs may have implications in assigning a new role of these cells as non-professional antigen presenting cells in the central nervous system.

null

Finding Novelty - 3.2 New property/feature - 3.2.1 New cell property

2/3/2025, 2:15:56 PM

openai

null

Finding Novelty - 3.2 New property/feature - 3.2.1 New cell property

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.1 New cell property", "reason": "The conclusion discusses the 'newly discovered immunological properties of NSPCs,' which indicates the identification of a new attribute or characteristic of these cells. This aligns with the classification of a new cell property, as it highlights a novel functional role of NSPCs in the immune response within the central nervous system." }

The conclusion discusses the 'newly discovered immunological properties of NSPCs,' which indicates the identification of a new attribute or characteristic of these cells. This aligns with the classification of a new cell property, as it highlights a novel functional role of NSPCs in the immune response within the central nervous system.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

19,529,782

Our study identified transcriptional networks at successive stages of tumor-development, i.e. from histological unaltered but transgenic lungs to nuclear atypia. Our SP-C/c-raf transgenic mouse model revealed interesting and novel candidate genes and pathways that provide clues on the mechanism forcing respiratory epithelium into dysplasia and subsequently cancer, some of which might also be useful in the molecular imaging and flagging of early stages of disease.

null

Finding Novelty - 3.2 New property/feature - 3.2.2 New candidate gene

2/3/2025, 2:16:02 PM

openai

null

Finding Novelty - 3.2 New property/feature - 3.2.2 New candidate gene

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.2 New candidate gene", "reason": "The conclusion mentions the identification of 'novel candidate genes and pathways' which suggests the discovery of new properties or features related to genes and pathways. This aligns with the classification of new candidate genes and potentially new pathways, indicating a finding novelty." }

The conclusion mentions the identification of 'novel candidate genes and pathways' which suggests the discovery of new properties or features related to genes and pathways. This aligns with the classification of new candidate genes and potentially new pathways, indicating a finding novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

11,107,461

Calculating risk using risk equations is a more accurate method to identify people at high risk for CAD than counting the number of risk factors present, especially for women, and the 1998 Canadian lipid screening guidelines are significantly better at identifying high-risk patients than the 1988 guidelines. Many of our findings were incorporated into the new 2000 guidelines.

null

Not novelty

2/3/2025, 2:16:27 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The text does not introduce novel ideas, methods, or findings. It discusses the accuracy of risk equations and compares different guidelines, but it does not claim any new or original contributions by the authors. The mention of 'new 2000 guidelines' refers to existing guidelines, not a novel contribution by the authors." }

The text does not introduce novel ideas, methods, or findings. It discusses the accuracy of risk equations and compares different guidelines, but it does not claim any new or original contributions by the authors. The mention of 'new 2000 guidelines' refers to existing guidelines, not a novel contribution by the authors.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

32,011,496

This study has limited inclusion and exclusion criteria and a well-controlled intervention. It will be the first randomized controlled trial to assess the efficacy and safety of PL in adults with reduced immunity. This study will provide insights into the mechanisms underlying the immune-stimulating effects of PL and lay the groundwork for further studies.

null

Concept Novelty - New attempt

2/3/2025, 2:16:33 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The text explicitly states that this will be the 'first randomized controlled trial' to assess the efficacy and safety of PL in adults with reduced immunity. This indicates a new attempt in the research field, as it is the first study of its kind." }

The text explicitly states that this will be the 'first randomized controlled trial' to assess the efficacy and safety of PL in adults with reduced immunity. This indicates a new attempt in the research field, as it is the first study of its kind.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

29,620,643

For the first-time telescope modification were used, to allow aorta to grow with a child. Such a strategy seems to be possible with long overlap and lack of oversizing between implants.

Endovascular stenting of a complicated type B aortic dissection in an 11-year-old patient: Case Report.

Medicine

2018 Apr

RATIONALE: Endovascular aortic repair in children in the case of aortic dissection (AD) is currently unavailable. This is the first report of aortic dissection type B in an 11-years old child treated in endovascular way. PATIENT CONCERNS: Complicated AD. Since bowel malperfusion and aortic rupture the surgery was necessary in emergency. DIAGNOSES: Computed angio tomography. INTERVENTION: The modified PETTICOAT technique (Provisional Extension To Induce Complete Attachment) was used. OUTCOME: Full recovery. LESSONS: For the first-time telescope modification were used, to allow aorta to grow with a child. Such a strategy seems to be possible with long overlap and lack of oversizing between implants.

Other new application method

2/3/2025, 2:17:38 PM

human

Other new application method

Method and Material Novelty - 2.2 New application method - 2.2.4 Method reapplication/method combination

{ "category": "2 Method and Material Novelty - 2.2 New application method - 2.2.4 Method reapplication/method combination", "reason": "The sentence describes the first-time use of telescope modification to allow the aorta to grow with a child, indicating a novel application of an existing method in a new context. This fits the category of method reapplication or method combination, as it involves adapting an existing technique for a new purpose." }

The sentence describes the first-time use of telescope modification to allow the aorta to grow with a child, indicating a novel application of an existing method in a new context. This fits the category of method reapplication or method combination, as it involves adapting an existing technique for a new purpose.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

26,489,083

This is the first study which investigates the parameters associated with IT in patients with PSC in clinical practice. A simplified AIH score >5 and a mHAI score >3, suggesting concomitant features of AIH, influenced the decision to introduce IT during the course of PSC. In German clinical practice, the cutoffs used to guide IT may be lower than recommended by current guidelines.

null

Concept Novelty - New attempt

2/3/2025, 2:18:33 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The sentence explicitly states 'This is the first study which investigates,' indicating that the research explores a new scientific research content that has not been explored before, thus classifying it as a new attempt in concept novelty." }

The sentence explicitly states 'This is the first study which investigates,' indicating that the research explores a new scientific research content that has not been explored before, thus classifying it as a new attempt in concept novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

32,493,090

The high prevalence of DTPs identified among older institutionalized adults strongly suggests the need to incorporate new pharmacist-led CMM services within existing institutional care facilities, to improve the care provided to nursing home residents.

null

Not Novelty

2/3/2025, 2:18:48 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence suggests the incorporation of new pharmacist-led CMM services, but it does not claim that this is a novel concept or method developed by the authors. It is more of a recommendation based on existing knowledge rather than an introduction of a novel idea or finding." }

The sentence suggests the incorporation of new pharmacist-led CMM services, but it does not claim that this is a novel concept or method developed by the authors. It is more of a recommendation based on existing knowledge rather than an introduction of a novel idea or finding.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

35,436,976

This trial will provide the first assessment of the effectiveness of the family systemic psychosocial support intervention for use in Lebanon, with important implications for the use of systemic, low-cost, non-specialist interventions for this age range.

null

Concept Novelty - New attempt

2/3/2025, 2:19:10 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The sentence explicitly mentions 'the first assessment,' indicating that this is the first time this specific intervention is being evaluated in Lebanon. This aligns with the 'New attempt' sub-label under 'Concept Novelty,' as it explores a new scientific research content which has not been explored before." }

The sentence explicitly mentions 'the first assessment,' indicating that this is the first time this specific intervention is being evaluated in Lebanon. This aligns with the 'New attempt' sub-label under 'Concept Novelty,' as it explores a new scientific research content which has not been explored before.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

19,295,951

This ecological study represents, to the authors' knowledge, the first statistically significant association between increasing rates of LNG EC distribution and decreasing abortion rates.

null

Finding Novelty - 3.3 New interaction - 3.3.3 New association

2/3/2025, 2:19:59 PM

openai

null

Finding Novelty - 3.3 New interaction - 3.3.3 New association

{ "category": "3 Finding Novelty - 3.3 New interaction - 3.3.3 New association", "reason": "The sentence claims novelty by stating it is the 'first statistically significant association' between LNG EC distribution and abortion rates. This indicates a new correlation or association among variables, which fits under the category of 'New interaction' and specifically 'New association'." }

The sentence claims novelty by stating it is the 'first statistically significant association' between LNG EC distribution and abortion rates. This indicates a new correlation or association among variables, which fits under the category of 'New interaction' and specifically 'New association'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

28,705,211

To the best of our knowledge, this case represents the first report of Streptococcus dysgalactiae subspecies equisimilis-induced streptococcal toxic-shock syndrome in a patient with breast cancer-related lymphedema. Breast cancer-related lymphedema is a common problem, and we must pay attention to invasive streptococcal soft tissue infections, particularly in elderly patients with chronic disease.

null

Finding Novelty - 3.1 New object - 3.1.6 New case

2/3/2025, 2:20:10 PM

openai

null

Finding Novelty - 3.1 New object - 3.1.6 New case

{ "category": "3 Finding Novelty - 3.1 New object - 3.1.6 New case", "reason": "The text explicitly claims novelty by stating 'this case represents the first report' of a specific medical condition, which is Streptococcus dysgalactiae subspecies equisimilis-induced streptococcal toxic-shock syndrome in a patient with breast cancer-related lymphedema. This indicates the identification or documentation of a newly diagnosed patient with a disease that has been observed for the first time, fitting the 'New case' sub-label under 'New object' in the taxonomy." }

The text explicitly claims novelty by stating 'this case represents the first report' of a specific medical condition, which is Streptococcus dysgalactiae subspecies equisimilis-induced streptococcal toxic-shock syndrome in a patient with breast cancer-related lymphedema. This indicates the identification or documentation of a newly diagnosed patient with a disease that has been observed for the first time, fitting the 'New case' sub-label under 'New object' in the taxonomy.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

24,814,920

These findings indicate that the CDX2 expression is decreased in UC, and moreover, the studies in Caco-2 cells have shed light on some of the molecular pathways of importance in the inhibitory effect of TNF-α. In addition, these studies have provided novel insight into the CDX2-mediated regulation of genes involved in the β-catenin degradation complex and in response to the pro-inflammatory cytokine, TNF-α. In particular, these findings indicate that CDX2 is involved in the crosstalk between TNF-α and the Wnt signalling pathway, which might be of importance in understanding the link between intestinal inflammation and tumourigenesis.

null

Concept Novelty - 1.2 New perspective

2/3/2025, 2:20:29 PM

openai

null

Concept Novelty - 1.2 New perspective

{ "category": "1 Concept Novelty - 1.2 New perspective", "reason": "The conclusion mentions 'novel insight' into the CDX2-mediated regulation of genes, which suggests a new way of interpreting the role of CDX2 in the context of TNF-α and the Wnt signalling pathway. This aligns with introducing a fresh subjective perspective or unique way of interpreting the objective findings, thus classifying it under '1.2 New perspective'." }

The conclusion mentions 'novel insight' into the CDX2-mediated regulation of genes, which suggests a new way of interpreting the role of CDX2 in the context of TNF-α and the Wnt signalling pathway. This aligns with introducing a fresh subjective perspective or unique way of interpreting the objective findings, thus classifying it under '1.2 New perspective'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

7,800,869

The 70% of screening rate in the group of pregnant women is still far from reaching the goal of 95% intended in the Plan de Salud Infantil in Navarra for 1993. A prevalence of 0.70 for positive HBsAg was observed. No geographical differences were observed in the distribution of HBV markers, but its prevalence was influenced by the type of residence, social class and risk exposure. A discussion follows whether a massive immunization program form newborns in Navarra is warranted.

null

Not Novelty

2/3/2025, 2:20:42 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not contain any explicit claims of novelty or use strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions. It summarizes existing findings and discusses potential implications without introducing new concepts, methods, or findings." }

The provided text does not contain any explicit claims of novelty or use strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions. It summarizes existing findings and discusses potential implications without introducing new concepts, methods, or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

22,321,609

Results showed significant changes in expression for 200 Wolbachia (29% of Wolbachia genes with expression signals in untreated worms) and 546 B. malayi array elements after treatment. These elements correspond to known genes and also to novel genes with unknown biological functions. Most differentially expressed Wolbachia genes were down-regulated after treatment (98.5%). In contrast, doxycycline had a mixed effect on B. malayi gene expression with many more genes being significantly up-regulated after treatment (85% of differentially expressed genes). Genes and processes involved in reproduction (gender-regulated genes, collagen, amino acid metabolism, ribosomal processes, and cytoskeleton) were down-regulated after doxycycline while up-regulated genes and pathways suggest adaptations for survival in response to stress (energy metabolism, electron transport, anti-oxidants, nutrient transport, bacterial signaling pathways, and immune evasion). Doxycycline reduced Wolbachia and significantly decreased bacterial gene expression. Wolbachia ribosomes are believed to be the primary biological target for doxycycline in filarial worms. B. malayi genes essential for reproduction, growth and development were also down-regulated; these changes are consistent with doxycycline effects on embryo development and reproduction. On the other hand, many B. malayi genes involved in energy production, electron-transport, metabolism, anti-oxidants, and others with unknown functions had increased expression signals after doxycycline treatment. These results suggest that female worms are able to compensate in part for the loss of Wolbachia so that they can survive, albeit without reproductive capacity. This study of doxycycline induced changes in gene expression has provided new clues regarding the symbiotic relationship between Wolbachia and B. malayi.

null

Finding Novelty - 3.4 Other new finding

2/3/2025, 2:20:52 PM

openai

null

Finding Novelty - 3.4 Other new finding

{ "category": "3 Finding Novelty - 3.4 Other new finding", "reason": "The conclusion mentions 'new clues regarding the symbiotic relationship between Wolbachia and B. malayi,' indicating a novel finding in terms of understanding this relationship. This does not introduce a new object, property, or interaction but provides new evidence or insights into the existing knowledge of the symbiotic relationship, which fits under 'Other new finding.'" }

The conclusion mentions 'new clues regarding the symbiotic relationship between Wolbachia and B. malayi,' indicating a novel finding in terms of understanding this relationship. This does not introduce a new object, property, or interaction but provides new evidence or insights into the existing knowledge of the symbiotic relationship, which fits under 'Other new finding.'

null

prompt-v2.1.txt

taxonomy-v2.2.txt

38,039,294

This study defined two molecular subtypes of osteosarcoma with different prognosis and tumor immune microenvironment status based on the expression of OSRGs, and provided a new risk assessment system for the prognosis of osteosarcoma.

null

Method and Material Novelty - 2.2 New application method - 2.2.2 New indicator/index/predictor

2/3/2025, 2:21:21 PM

openai

null

Method and Material Novelty - 2.2 New application method - 2.2.2 New indicator/index/predictor

{ "category": "2 Method and Material Novelty - 2.2 New application method - 2.2.2 New indicator/index/predictor", "reason": "The conclusion mentions the provision of a 'new risk assessment system for the prognosis of osteosarcoma,' which indicates the development of a novel metric for assessing outcomes. This aligns with the sub-label 'New indicator/index/predictor' under 'New application method.'" }

The conclusion mentions the provision of a 'new risk assessment system for the prognosis of osteosarcoma,' which indicates the development of a novel metric for assessing outcomes. This aligns with the sub-label 'New indicator/index/predictor' under 'New application method.'

null

prompt-v2.1.txt

taxonomy-v2.2.txt

25,815,481

During the first decade of 2000, Chinese FSWs' self-reported risk behaviours have decreased significantly while HIV testing has increased. Further outreach and intervention efforts are needed to encourage condom use with regular partners, continue promotion of HIV testing, and provide resources for the most vulnerable FSW, particularly low tier FSW, who may have limited access to sexual health and prevention programs.

null

Not Novelty

2/3/2025, 2:21:56 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not contain any explicit claims of novelty or use strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions. It summarizes existing knowledge and suggests further actions, which aligns with the classification of '4 Not Novelty.'" }

The provided text does not contain any explicit claims of novelty or use strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions. It summarizes existing knowledge and suggests further actions, which aligns with the classification of '4 Not Novelty.'

null

prompt-v2.1.txt

taxonomy-v2.2.txt

36,325,669

Our results confirm the role of elevated inflammatory and coagulation response in DVT development in the first month after the infection, but not in non-recent COVID-19 or non-COVID-19 patients.

null

Not Novelty

2/3/2025, 2:22:56 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence summarizes findings related to the role of inflammatory and coagulation response in DVT development after infection. It does not introduce any novel ideas, methods, or findings, nor does it use terms like 'first,' 'novel,' 'innovation,' or 'new' to claim novelty. Therefore, it is classified as not novelty." }

The sentence summarizes findings related to the role of inflammatory and coagulation response in DVT development after infection. It does not introduce any novel ideas, methods, or findings, nor does it use terms like 'first,' 'novel,' 'innovation,' or 'new' to claim novelty. Therefore, it is classified as not novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

29,937,879

Disruption in the salivary environment and changes in microbial ecology with increased load of cariogenic bacteria were found in diabetic and cardiac patients. This study brings forward new evidence of a markedly higher load of

null

Other new finding

2/3/2025, 2:23:41 PM

openai

null

Other new finding

{ "category": "3.4 Other new finding", "reason": "The conclusion mentions 'new evidence' of a markedly higher load of cariogenic bacteria in diabetic and cardiac patients, which suggests a novel finding in the context of the study. This aligns with the category of discovering new results and knowledge, specifically under 'Other new finding' as it refers to the objective findings of the study." }

The conclusion mentions 'new evidence' of a markedly higher load of cariogenic bacteria in diabetic and cardiac patients, which suggests a novel finding in the context of the study. This aligns with the category of discovering new results and knowledge, specifically under 'Other new finding' as it refers to the objective findings of the study.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

30,236,149

This is the first study to determine the feasibility and effectiveness of Tai Chi in treating overweight/obese adolescent and young women with PCOS. The trial will provide evidence to assess the feasibility of a future multicenter, randomized controlled trial.

null

Concept Novelty - New attempt

2/3/2025, 2:24:43 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The sentence explicitly states that this is the 'first study' to determine the feasibility and effectiveness of Tai Chi in treating a specific population, indicating a new attempt in scientific research content." }

The sentence explicitly states that this is the 'first study' to determine the feasibility and effectiveness of Tai Chi in treating a specific population, indicating a new attempt in scientific research content.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

26,109,110

Retention in HIV care prior to ART eligibility in sub-Saharan Africa has been insufficiently described so far leaving major research gaps, especially regarding long-term retention rates and sociodemographic, economic, clinical and programmatic logistic determinants. The prospective follow-up of newly diagnosed individuals is required to better evaluate attrition prior to ART eligibility among HIV-infected people.

null

Not Novelty

2/3/2025, 2:25:07 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text does not explicitly claim any novel contributions by the authors. It highlights existing research gaps and the need for further study, but does not introduce new ideas, methods, or findings. The mention of 'insufficiently described' and 'required to better evaluate' indicates a need for more research rather than presenting a novel contribution." }

The text does not explicitly claim any novel contributions by the authors. It highlights existing research gaps and the need for further study, but does not introduce new ideas, methods, or findings. The mention of 'insufficiently described' and 'required to better evaluate' indicates a need for more research rather than presenting a novel contribution.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,936,391

The associations of occupational sitting time with cardio-metabolic risk factors were fewer and weaker compared to leisure-time sitting. Yet, the joint associations of occupational and leisure-time sitting with cardio-metabolic risk factors were higher than the separate. Our findings amplify the need for further focus in this area prior to making assumptions about equivalent health risks across sedentary behaviors. To our knowledge, this is the first study to contrast the deleterious associations of prolonged occupational and leisure-time sitting, both separately and jointly.

null

Concept Novelty - New attempt

2/3/2025, 2:25:29 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The conclusion explicitly states that this is the 'first study' to contrast the deleterious associations of prolonged occupational and leisure-time sitting, both separately and jointly. This indicates a new attempt in exploring this specific research content, which has not been explored before." }

The conclusion explicitly states that this is the 'first study' to contrast the deleterious associations of prolonged occupational and leisure-time sitting, both separately and jointly. This indicates a new attempt in exploring this specific research content, which has not been explored before.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

16,167,739

Chronic osteomyelitis is a debilitating dirty disease endemic in the peasantry communities. It persists because of delay in seeking medical treatment because the first line of treatment is mainly herbs where the terminal phalanges were involved. Sequestrectomy and curettage were a better option to disarticulation because the function of the finger is not interfered with. The biggest number of cases seen involved the phalanges (45.3%) followed by the tibia 21.6% because of the nature of occupation of the rural communities.

null

Not Novelty

2/3/2025, 2:25:35 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not contain any explicit claims of novelty or use strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions. It primarily describes existing knowledge and observations about chronic osteomyelitis in peasantry communities, including treatment practices and the prevalence of the disease in certain bones. Therefore, it is classified as '4 Not Novelty.'" }

The provided text does not contain any explicit claims of novelty or use strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own novel contributions. It primarily describes existing knowledge and observations about chronic osteomyelitis in peasantry communities, including treatment practices and the prevalence of the disease in certain bones. Therefore, it is classified as '4 Not Novelty.'

null

prompt-v2.1.txt

taxonomy-v2.2.txt

26,908,532

Many patients with suspected seizures could potentially be treated more effectively and at lower cost by modifying ambulance call handling protocols. The development of innovative care pathways could give call handlers and paramedics alternatives to hospital transportation. Increased adoption of care plans could reduce 999 calls and could increase the rates of successful home or community treatment.

null

Not Novelty

2/3/2025, 2:25:40 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text discusses potential improvements in ambulance call handling protocols and care pathways, but it does not explicitly claim any novel contributions by the authors. The use of 'innovative' is not directly linked to a specific new method or finding introduced by the authors, and the text primarily suggests potential benefits rather than presenting new research or findings." }

The text discusses potential improvements in ambulance call handling protocols and care pathways, but it does not explicitly claim any novel contributions by the authors. The use of 'innovative' is not directly linked to a specific new method or finding introduced by the authors, and the text primarily suggests potential benefits rather than presenting new research or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

2,072,775

The pharmacokinetic profile of this new preparation fits that proposed by others to produce a selective inhibition of thromboxane synthesis by platelets.

null

Not Novelty

2/3/2025, 2:25:51 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence describes the pharmacokinetic profile of a new preparation but does not claim any novelty in terms of concept, method, or findings. It mentions that the profile fits what has been proposed by others, indicating that it aligns with existing knowledge rather than introducing something new." }

The sentence describes the pharmacokinetic profile of a new preparation but does not claim any novelty in terms of concept, method, or findings. It mentions that the profile fits what has been proposed by others, indicating that it aligns with existing knowledge rather than introducing something new.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

30,732,201

Although valsartan-induced allergy has been reported previously, AIN was firstly recognized as a severe complication of this drug. We suggest when there is a ARB-associated continuous deterioration of kidney function for patients without renal insufficiency, renal artery stenosis, heart failure or hypovolemia, AIN should be thought of and therapy with glucocorticoid should be considered if necessary.

null

Finding Novelty - 3.1 New object - 3.1.6 New case

2/3/2025, 2:25:57 PM

openai

null

Finding Novelty - 3.1 New object - 3.1.6 New case

{ "category": "3 Finding Novelty - 3.1 New object - 3.1.6 New case", "reason": "The text mentions that AIN (Acute Interstitial Nephritis) was 'firstly recognized as a severe complication' of valsartan, indicating the identification of a new case of a known drug causing a specific severe complication. This aligns with the classification of a 'New case' under 'Finding Novelty'." }

The text mentions that AIN (Acute Interstitial Nephritis) was 'firstly recognized as a severe complication' of valsartan, indicating the identification of a new case of a known drug causing a specific severe complication. This aligns with the classification of a 'New case' under 'Finding Novelty'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

33,228,739

The iCPB trial is the first to explore ILPC on the clinical outcome of adult cardiac surgery patients. The results are expected to provide potential evidences about whether ILPC could reduce the morbidity and mortality and improve the cardiac function and quality of life. Therefore, the results will provide a rationale for the evaluation of the potentially clinically relevant benefit of intralipid therapy.

null

Concept Novelty - New attempt

2/3/2025, 2:26:03 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The sentence explicitly states that the iCPB trial is the 'first to explore' ILPC on the clinical outcome of adult cardiac surgery patients, indicating a new scientific research content that has not been explored before. This aligns with the 'New attempt' sub-label under 'Concept Novelty'." }

The sentence explicitly states that the iCPB trial is the 'first to explore' ILPC on the clinical outcome of adult cardiac surgery patients, indicating a new scientific research content that has not been explored before. This aligns with the 'New attempt' sub-label under 'Concept Novelty'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

24,029,192

M. tuberculosis was isolated from 75 out of 543 suspected cases of pulmonary/extrapulmonary TB. Three of the total 75 M. tuberculosis isolates (4%) showed resistance to any one of the first line drugs. Prevalence of MDR-TB was 1.3%. The sequencing of single MDR strain showed mutations at codons 516, 517, and 518. Amplification of rpoB and sequential analysis of the amplicon is a better way of detection of mutation and the evidence of new mutation in this study indicate that mutations continue to arise, probably due to the ability of M. tuberculosis to adapt to drug exposure.

null

Finding Novelty - 3.2 New property/feature - 3.2.7 Other new property/feature

2/3/2025, 2:26:08 PM

openai

null

Finding Novelty - 3.2 New property/feature - 3.2.7 Other new property/feature

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.7 Other new property/feature", "reason": "The conclusion mentions the 'evidence of new mutation' in the study, which indicates the discovery of a new attribute or characteristic of M. tuberculosis related to drug resistance. This aligns with the classification of a new property/feature, specifically under 'Other new property/feature' as it does not fit into the more specific sub-categories provided." }

The conclusion mentions the 'evidence of new mutation' in the study, which indicates the discovery of a new attribute or characteristic of M. tuberculosis related to drug resistance. This aligns with the classification of a new property/feature, specifically under 'Other new property/feature' as it does not fit into the more specific sub-categories provided.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

27,490,242

A single genetic lineage of HBoV1 is speculated as a viral pathogen of respiratory infection and causes both comorbid infection and acute gastroenteritis. Additionally, a new cluster of HBoV2 is prevalent in China, which may infect the host through sites other than the respiratory tract.

null

Not Novelty

2/3/2025, 2:26:16 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not explicitly claim novelty in the research work using strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' in a way that directly refers to their own novel contributions. It summarizes existing knowledge about HBoV1 and HBoV2 without introducing new ideas, methods, or findings." }

The provided text does not explicitly claim novelty in the research work using strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' in a way that directly refers to their own novel contributions. It summarizes existing knowledge about HBoV1 and HBoV2 without introducing new ideas, methods, or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

35,533,495

These data demonstrate that SARS-CoV-2 vaccination in patients with prior SARS-CoV-2 infection induces a new antigen-specific repertoire and sheds light on the differential immune responses induced by vaccination versus natural infection.

null

Not novelty

2/3/2025, 2:27:20 PM

human

Not novelty

Finding Novelty - 3.2 New property/feature - 3.2.7 Other new property/feature

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.7 Other new property/feature", "reason": "The sentence claims that SARS-CoV-2 vaccination in patients with prior infection induces a 'new antigen-specific repertoire,' which suggests the identification of a new attribute or characteristic of the immune response. This aligns with the category of discovering a new property or feature of an existing object, in this case, the immune response to vaccination." }

The sentence claims that SARS-CoV-2 vaccination in patients with prior infection induces a 'new antigen-specific repertoire,' which suggests the identification of a new attribute or characteristic of the immune response. This aligns with the category of discovering a new property or feature of an existing object, in this case, the immune response to vaccination.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

27,571,353

This analysis highlights individual variation in sleep throughout the process of inpatient treatment and transition to outpatient aftercare in individuals with alcohol dependence. Collecting quantitative and qualitative data concurrently and combining emerging themes from qualitative data with quantitative analyses allowed for a more thorough examination of this relatively novel area of research and provided information that can be utilized to inform future behavioral sleep interventions.

null

Not Novelty

2/3/2025, 2:28:31 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion mentions a 'relatively novel area of research,' but this does not explicitly claim novelty in the authors' own research work. The statement refers to the area of research being novel, not the specific contributions or findings of the study itself. Therefore, it does not meet the criteria for novelty classification." }

The conclusion mentions a 'relatively novel area of research,' but this does not explicitly claim novelty in the authors' own research work. The statement refers to the area of research being novel, not the specific contributions or findings of the study itself. Therefore, it does not meet the criteria for novelty classification.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

35,057,834

This adequately powered randomized controlled trial will provide clinically relevant information about whether targeting insomnia is effective for improving treatment outcomes among treatment-seeking adults with AUD. Additionally, the study will offer new scientific insights on the impact of an evidence-based non-medication treatment for insomnia on a candidate mechanism of sleep dysfunction in this population - sleep homeostasis.

null

Concept Novelty - 1.2 New perspective

2/3/2025, 2:28:46 PM

openai

null

Concept Novelty - 1.2 New perspective

{"category": "1 Concept Novelty - 1.2 New perspective", "reason": "The conclusion mentions that the study will offer 'new scientific insights' on the impact of a non-medication treatment for insomnia on sleep homeostasis in adults with AUD. This indicates a fresh subjective perspective or unique way of interpreting the findings, which aligns with the 'New perspective' sub-label under Concept Novelty."}

The conclusion mentions that the study will offer 'new scientific insights' on the impact of a non-medication treatment for insomnia on sleep homeostasis in adults with AUD. This indicates a fresh subjective perspective or unique way of interpreting the findings, which aligns with the 'New perspective' sub-label under Concept Novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

27,525,701

Based on the interpretation of the clinical symptoms of psychosomatic medicine, the treatment of chronic non-infectious diseases includes at least three dimensions: the first is the etiological treatment, the second is the pathophysiological and pathopsychological dimension, and the third is symptomatic treatment. The unified psychosomatic point of view and diverse clinical thinking modes are aimed at identifying different classes of somatic symptoms and important prerequisites for the treatment of these symptoms. We registered the study with the Chinese Clinical Trial Registry and it was approved by the West China Hospital, Sichuan University ethics committee.

null

Not Novelty

2/3/2025, 2:28:53 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not explicitly claim any novelty in terms of new concepts, methods, or findings. It describes the dimensions of treatment for chronic non-infectious diseases and mentions the registration and ethical approval of the study, but does not introduce any new ideas or discoveries. Therefore, it should be classified as '4 Not Novelty'." }

The provided text does not explicitly claim any novelty in terms of new concepts, methods, or findings. It describes the dimensions of treatment for chronic non-infectious diseases and mentions the registration and ethical approval of the study, but does not introduce any new ideas or discoveries. Therefore, it should be classified as '4 Not Novelty'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

24,748,395

DP is superior to AL from both the clinical and economic perspectives for treatment of uncomplicated P. falciparum malaria in young children. A paediatric dispersible formulation of DP is under development and should facilitate a targeted deployment of this antimalarial drug. The use of DP as first-line antimalarial drug in paediatric malaria patients in moderate to high transmission areas of Africa merits serious consideration by health policymakers.

null

Not novelty

2/3/2025, 2:29:10 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The conclusion does not explicitly claim any novel contribution by the authors. It discusses the superiority of DP over AL and the development of a pediatric formulation, but these are not presented as novel findings or methods. The mention of 'first-line antimalarial drug' is a recommendation rather than a claim of novelty." }

The conclusion does not explicitly claim any novel contribution by the authors. It discusses the superiority of DP over AL and the development of a pediatric formulation, but these are not presented as novel findings or methods. The mention of 'first-line antimalarial drug' is a recommendation rather than a claim of novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

9,087,184

In contrast with previous studies, possible HCV transmission modes were identified for almost all respondents. Most respondents in this community were IDUs. Non-parenteral transmission appeared minimal. Novel approaches to preventing HCV transmission in IDUs are needed.

null

Not Novelty

2/3/2025, 2:29:54 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text does not explicitly claim novelty in the authors' own research work. It mentions 'novel approaches' in a general context, indicating a need for new methods rather than presenting a novel contribution by the authors themselves. Therefore, it does not meet the criteria for novelty classification." }

The text does not explicitly claim novelty in the authors' own research work. It mentions 'novel approaches' in a general context, indicating a need for new methods rather than presenting a novel contribution by the authors themselves. Therefore, it does not meet the criteria for novelty classification.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

18,088,043

At the time when the newborn was diagnosed to have PHP, there was no indication whether it was of a permanent or transient form. A considerably lower number of patients have a transitory form of PHP, which is then confirmed in the infant period by a gradual reduction and withdrawal of therapy, with sustaining serum calcium and PTH within normal limits.

null

Not novelty

2/3/2025, 2:30:03 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The text does not introduce any novel ideas, methods, or findings. It describes existing knowledge about the diagnosis and progression of PHP in newborns, specifically mentioning the transient form and its confirmation process. There are no claims of new research, methods, or findings in this conclusion." }

The text does not introduce any novel ideas, methods, or findings. It describes existing knowledge about the diagnosis and progression of PHP in newborns, specifically mentioning the transient form and its confirmation process. There are no claims of new research, methods, or findings in this conclusion.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

29,419,687

The synchronous DTC and NHL is rare. To date, there is no standardized approach due to lack of experience. We suggest lymphoma first approach with synchronized and tailored multidisciplinary efforts. The molecular mechanisms of this link are poorly understood and yet remain to be elucidated.

null

Not Novelty

2/3/2025, 2:30:12 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text does not explicitly claim any novel contributions by the authors. It discusses the rarity of synchronous DTC and NHL, the lack of standardized approaches, and suggests a treatment strategy without indicating it as a novel method or finding. The mention of poorly understood molecular mechanisms does not imply a new discovery or theory proposed by the authors." }

The text does not explicitly claim any novel contributions by the authors. It discusses the rarity of synchronous DTC and NHL, the lack of standardized approaches, and suggests a treatment strategy without indicating it as a novel method or finding. The mention of poorly understood molecular mechanisms does not imply a new discovery or theory proposed by the authors.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

26,471,509

Strengths to leverage for the implementation of the seven programs include: (1) synergy between clinical and research teams; (2) stakeholders working together; (3) motivation of clinicians; and (4) the fact that the programs are evidence-based. Weaknesses to address include: (1) insufficient resources; (2) organizational change within the clinical sites; (3) lack of referrals from primary care physicians; and (4) lack of access to programs. Strengths to leverage for the evaluation of these programs include: (1) engagement of stakeholders and (2) sharing of knowledge between clinical sites. Weaknesses to address include: (1) lack of referrals; (2) difficulties with data collection; and (3) difficulties in identifying indicators and control groups. Opportunities for both themes include: (1) fostering new and existing partnerships and stakeholder relations; (2) seizing funding opportunities; (3) knowledge transfer; (4) supporting the transformation of professional roles; (5) expand the use of health information technology; and (6) conduct cost evaluations. Fifteen recommendations related to mobilisation of primary care physicians, support for the transformation of professional roles, and strategies aimed at facilitating the implementation and evaluation of chronic disease management programs were formulated based on the discussions at this knowledge translation event. The results from this knowledge translation day will help inform the sustainability of these seven chronic disease management programs in Quebec and the implementation and evaluation of similar programs elsewhere.

null

Not Novelty

2/3/2025, 2:30:28 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text summarizes existing knowledge and provides recommendations based on discussions at a knowledge translation event. It does not introduce novel ideas, methods, or findings. The mention of 'new and existing partnerships' refers to opportunities rather than novel contributions by the authors." }

The text summarizes existing knowledge and provides recommendations based on discussions at a knowledge translation event. It does not introduce novel ideas, methods, or findings. The mention of 'new and existing partnerships' refers to opportunities rather than novel contributions by the authors.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

14,973,976

Though promising, the data are not strong enough to make a general recommendation to use Oscillococcinum for first-line treatment of influenza and influenza-like syndrome. Further research is warranted but required sample sizes are large. Current evidence does not support a preventative effect of Oscillococcinum-like homeopathic medicines in influenza and influenza-like syndromes.

null

Not Novelty

2/3/2025, 2:31:33 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion does not introduce any novel ideas, methods, or findings. It discusses the current state of evidence regarding Oscillococcinum and suggests that further research is needed, but it does not claim any new discovery or innovation. The mention of 'first-line treatment' is not related to novelty but rather to the potential application of the treatment." }

The conclusion does not introduce any novel ideas, methods, or findings. It discusses the current state of evidence regarding Oscillococcinum and suggests that further research is needed, but it does not claim any new discovery or innovation. The mention of 'first-line treatment' is not related to novelty but rather to the potential application of the treatment.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

21,437,262

Non-indigenous richness decreased with increasing metal concentrations, contradicting previous investigations that evaluate the influence of heavy metal pollution on diversity and invasibility of fouling assemblages. These results provide first insights on how the invasive species pool in a certain region may play a key role in the disturbance vs. non-indigenous diversity relationship.

null

Concept Novelty - 1.2 New perspective

2/3/2025, 2:31:49 PM

openai

null

Concept Novelty - 1.2 New perspective

{ "category": "1 Concept Novelty - 1.2 New perspective", "reason": "The conclusion mentions 'first insights' which indicates a novel perspective on the relationship between invasive species and metal concentrations. This suggests a new way of interpreting the influence of heavy metal pollution on diversity, which aligns with the 'New perspective' sub-label under Concept Novelty." }

The conclusion mentions 'first insights' which indicates a novel perspective on the relationship between invasive species and metal concentrations. This suggests a new way of interpreting the influence of heavy metal pollution on diversity, which aligns with the 'New perspective' sub-label under Concept Novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

24,131,861

Optimised treatment as usual, combining psychotherapy and structured care from a family doctor, should be regarded as solid baseline treatment for adult outpatients with anorexia nervosa. Focal psychodynamic therapy proved advantageous in terms of recovery at 12-month follow-up, and enhanced cognitive behaviour therapy was more effective with respect to speed of weight gain and improvements in eating disorder psychopathology. Long-term outcome data will be helpful to further adapt and improve these novel manual-based treatment approaches.

null

Not Novelty

2/3/2025, 2:32:55 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion discusses the effectiveness of existing treatment approaches and suggests that long-term outcome data will help improve these treatments. Although the term 'novel' is used, it refers to existing manual-based treatment approaches rather than introducing new methods or findings. Therefore, it does not meet the criteria for novelty classification." }

The conclusion discusses the effectiveness of existing treatment approaches and suggests that long-term outcome data will help improve these treatments. Although the term 'novel' is used, it refers to existing manual-based treatment approaches rather than introducing new methods or findings. Therefore, it does not meet the criteria for novelty classification.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

11,903,030

Plasma free metanephrines provide the best test for excluding or confirming pheochromocytoma and should be the test of first choice for diagnosis of the tumor.

null

Not Novelty

2/3/2025, 2:33:03 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence does not introduce any novel ideas, methods, or findings. It summarizes existing knowledge about the use of plasma free metanephrines for diagnosing pheochromocytoma, without claiming any new or first-time discovery or application by the authors." }

The sentence does not introduce any novel ideas, methods, or findings. It summarizes existing knowledge about the use of plasma free metanephrines for diagnosing pheochromocytoma, without claiming any new or first-time discovery or application by the authors.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

22,584,519

A weak increased all-cause mortality was observed in men with higher traditional Sami diet scores. However, due to the complexity in defining a "traditional Sami" diet, and the limitations of our questionnaire for this purpose, the study should be considered exploratory, a first attempt to relate a "traditional Sami" dietary pattern to health endpoints. Further investigation of cohorts with more detailed information on dietary and lifestyle items relevant for traditional Sami culture is warranted.

null

Concept Novelty - New attempt

2/3/2025, 2:34:26 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The conclusion explicitly mentions that the study is a 'first attempt' to relate a 'traditional Sami' dietary pattern to health endpoints. This indicates that the research explores a new scientific content which has not been explored before, fitting the 'New attempt' sub-label under 'Concept Novelty'." }

The conclusion explicitly mentions that the study is a 'first attempt' to relate a 'traditional Sami' dietary pattern to health endpoints. This indicates that the research explores a new scientific content which has not been explored before, fitting the 'New attempt' sub-label under 'Concept Novelty'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

35,969,339

Self-reported competencies in operative trauma skills across all subgroups were sub-standard with incremental levels of perceived competence proportional to years of surgical training. Our data supports the necessity of the new curriculum, in addition to modern training pathways with direct exposure to operative trauma surgery involving dedicated trauma centres and networks, and responsibility of training pathways in the provision of training trauma surgery.

null

Not Novelty

2/3/2025, 2:34:49 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion discusses the necessity of a new curriculum and modern training pathways, but it does not explicitly claim novelty in the research work itself. The mention of 'new curriculum' refers to an application or implementation rather than a novel research contribution. Therefore, it does not meet the criteria for novelty classification." }

The conclusion discusses the necessity of a new curriculum and modern training pathways, but it does not explicitly claim novelty in the research work itself. The mention of 'new curriculum' refers to an application or implementation rather than a novel research contribution. Therefore, it does not meet the criteria for novelty classification.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

18,049,429

Comparison of CD30 expression by TECs and thymocytes during the late first trimester and second trimester suggests an important role for CD30 in thymic selection.

null

Not Novelty

2/3/2025, 2:35:19 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence does not explicitly claim novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the authors' own contributions. It suggests a role for CD30 in thymic selection based on a comparison, but this does not indicate a novel concept, method, or finding as per the specified criteria." }

The sentence does not explicitly claim novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the authors' own contributions. It suggests a role for CD30 in thymic selection based on a comparison, but this does not indicate a novel concept, method, or finding as per the specified criteria.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

30,131,307

These results suggest that NGF treatment could alleviate various age-related hypogonadism symptoms in male SAMP8 and may be usefulness for age-related hypogonadotrophic hypogonadism and its related subfertility. FUND: National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province, the Science and Technology Plan Project of Guangzhou, Wenzhou Science & Technology Bureau, Guangdong Province Pearl River Scholar Fund, Guangdong province science and technology innovation leading Scholar Fund.

null

Not Novelty

2/3/2025, 2:35:24 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion does not explicitly claim any novelty in terms of new concepts, methods, or findings. It suggests potential therapeutic effects of NGF treatment on age-related hypogonadism symptoms, but does not indicate that this is a novel discovery or approach. The mention of funding sources further supports that this is a summary of research findings rather than a claim of novelty." }

The conclusion does not explicitly claim any novelty in terms of new concepts, methods, or findings. It suggests potential therapeutic effects of NGF treatment on age-related hypogonadism symptoms, but does not indicate that this is a novel discovery or approach. The mention of funding sources further supports that this is a summary of research findings rather than a claim of novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

26,736,134

This is the first study to demonstrate an association between NIRS-based StO2 measurements and peristaltic activity visualized by ultrasound imaging. NIRS may offer a continuous, noninvasive method to assess motility. This may have significant implications in premature infants at risk for feeding intolerance or necrotizing enterocolitis.

null

Finding Novelty - 3.3 New interaction - 3.3.3 New association

2/3/2025, 2:35:51 PM

openai

null

Finding Novelty - 3.3 New interaction - 3.3.3 New association

{ "category": "3 Finding Novelty - 3.3 New interaction - 3.3.3 New association", "reason": "The sentence explicitly claims novelty by stating 'This is the first study to demonstrate an association between NIRS-based StO2 measurements and peristaltic activity visualized by ultrasound imaging.' This indicates a new correlation or association among variables, which fits under the category of 'New interaction' and specifically 'New association.'" }

The sentence explicitly claims novelty by stating 'This is the first study to demonstrate an association between NIRS-based StO2 measurements and peristaltic activity visualized by ultrasound imaging.' This indicates a new correlation or association among variables, which fits under the category of 'New interaction' and specifically 'New association.'

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,176,518

The discovery of this new ALB mutation, probably inherited from a common ancestor, sheds light on the molecular mechanism underlying the analbuminemic trait and may serve in the development of a rapid genetic test for the identification of a-symptomatic heterozygous carriers in the Druze population in the Galilee.

null

Other new object

2/3/2025, 2:39:57 PM

human

Other new object

Finding Novelty - 3.1 New object - 3.1.3 New gene

{ "category": "3 Finding Novelty - 3.1 New object - 3.1.3 New gene", "reason": "The sentence describes the discovery of a new ALB mutation, which is a novel genetic finding. This fits under the category of 'Finding Novelty' as it involves the identification of a new gene mutation. The mention of 'new ALB mutation' indicates the novelty of the genetic discovery." }

The sentence describes the discovery of a new ALB mutation, which is a novel genetic finding. This fits under the category of 'Finding Novelty' as it involves the identification of a new gene mutation. The mention of 'new ALB mutation' indicates the novelty of the genetic discovery.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,390,963

An optimized culture of Map in a bioreactor was established to purify the native map-HBHA from a Map lysate by heparin-Sepharose chromatography. The availability of this antigen offers the possibility to study the structure of the protein and to examine its role in pathogenicity, in particular to better understand the specific interactions of Map with the intestinal tissue. The map-HBHA obtained in its native immunogenic form may also be useful to improve the diagnostic test, especially for the development of a new T-cell-based interferon gamma release assays.

null

Not Novelty

2/3/2025, 2:41:21 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion describes the establishment of a culture and purification process for a specific antigen, which may offer possibilities for future studies and diagnostic improvements. However, it does not explicitly claim any novel contributions using terms like 'first,' 'novel,' 'innovation,' or 'new' in the context of their own research work. The mention of 'new T-cell-based interferon gamma release assays' refers to potential applications rather than a novel development presented in the study." }

The conclusion describes the establishment of a culture and purification process for a specific antigen, which may offer possibilities for future studies and diagnostic improvements. However, it does not explicitly claim any novel contributions using terms like 'first,' 'novel,' 'innovation,' or 'new' in the context of their own research work. The mention of 'new T-cell-based interferon gamma release assays' refers to potential applications rather than a novel development presented in the study.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

30,473,651

The overall prevalence of long-term outcomes was not largely different among the VLBWI born between 2013 and 2014. This study is the first large national data study of long-term outcomes.

null

Concept Novelty - New attempt

2/3/2025, 2:44:04 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The sentence explicitly claims novelty by stating 'This study is the first large national data study of long-term outcomes.' The use of 'first' indicates that this is a new attempt to explore this specific research content, which has not been explored before on a national scale." }

The sentence explicitly claims novelty by stating 'This study is the first large national data study of long-term outcomes.' The use of 'first' indicates that this is a new attempt to explore this specific research content, which has not been explored before on a national scale.

Method and Material Novelty - 2.3 New dataset/material

Let's analyze this step by step: 1. Identify novelty indicators: - "first large national data study" suggests novelty - Specifically points to a novel research approach/dataset 2. Match against taxonomy: - This is a novel research method - More specifically, a novel dataset/research approach - Falls under category 2.3 "New dataset/material" 3. Reasoning: - The authors explicitly claim this is the "first" large national data study of long-term outcomes - This indicates a novel approach to studying long-term outcomes in very low birth weight infants (VLBWI) - The novelty is in the comprehensive national-level dataset and approach 4. JSON Output: { "category": "2 Method and Material Novelty - 2.3 New dataset/material", "reason": "The study is explicitly described as the 'first large national data study of long-term outcomes', indicating a novel dataset and research approach for examining long-term outcomes in very low birth weight infants (VLBWI)." } The classification focuses on the methodological novelty of creating a comprehensive national-level dataset for studying long-term outcomes.

The study is explicitly described as the 'first large national data study of long-term outcomes', indicating a novel dataset and research approach for examining long-term outcomes in very low birth weight infants (VLBWI).

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,029,191

Bone turnover and metabolism did not differ significantly in CIS and MS patients with prevalent low bone mass compared to controls. These findings indicate that the bone deficit in patients newly diagnosed with MS and CIS is not caused by recent acceleration of bone loss, and are compatible with shared etiological factors between MS and low bone mass.

null

Not novelty

2/3/2025, 2:44:27 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The provided text does not contain any explicit claims of novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the authors' own contributions. It summarizes findings regarding bone turnover and metabolism in CIS and MS patients, indicating no significant differences compared to controls and suggesting shared etiological factors. This is a summary of existing knowledge rather than an introduction of novel ideas, methods, or findings." }

The provided text does not contain any explicit claims of novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the authors' own contributions. It summarizes findings regarding bone turnover and metabolism in CIS and MS patients, indicating no significant differences compared to controls and suggesting shared etiological factors. This is a summary of existing knowledge rather than an introduction of novel ideas, methods, or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,696,786

Low rates of both condom use and HIV testing among men in a high HIV prevalence setting are worrisome and indicate an urgent need to develop innovative behavioral strategies to address this shortfall. Condom use is poor in this population whether tested or not tested for HIV, indicating no association between condom use and HIV testing.

null

Not Novelty

2/3/2025, 2:45:24 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not explicitly claim any novel contributions by the authors. It highlights existing issues and the need for innovative strategies but does not introduce any new concepts, methods, or findings. Therefore, it is classified as '4 Not Novelty'." }

The provided text does not explicitly claim any novel contributions by the authors. It highlights existing issues and the need for innovative strategies but does not introduce any new concepts, methods, or findings. Therefore, it is classified as '4 Not Novelty'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

26,241,312

Taken together, our data demonstrate, for the first time, that SS mice display features of urinary bladder dysfunction, leading to impairment in urinary continence, which may have an important role in the pathogenesis of the enuresis and infections observed the SCD patients.

null

Other new finding

2/3/2025, 2:48:33 PM

human

Other new finding

Finding Novelty - 3.2 New property/feature - 3.2.7 Other new property/feature

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.7 Other new property/feature", "reason": "The sentence claims novelty by stating 'for the first time' that SS mice display features of urinary bladder dysfunction. This indicates the discovery of a new property or feature of SS mice related to urinary bladder dysfunction, which has not been previously identified." }

The sentence claims novelty by stating 'for the first time' that SS mice display features of urinary bladder dysfunction. This indicates the discovery of a new property or feature of SS mice related to urinary bladder dysfunction, which has not been previously identified.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

34,434,660

This study demonstrated that ferroptosis-related gene signatures can be used as a potential predictor for the prognosis of LUAD, thus providing a novel strategy for individualized treatment in LUAD patients.

null

Method and Material Novelty - 2.2 New application method - 2.2.2 New indicator/index/predictor

2/3/2025, 2:48:55 PM

openai

null

Method and Material Novelty - 2.2 New application method - 2.2.2 New indicator/index/predictor

{ "category": "2 Method and Material Novelty - 2.2 New application method - 2.2.2 New indicator/index/predictor", "reason": "The conclusion claims the development of a 'novel strategy' for individualized treatment in LUAD patients by using ferroptosis-related gene signatures as a potential predictor for prognosis. This indicates a new application method, specifically a new indicator or predictor for clinical use." }

The conclusion claims the development of a 'novel strategy' for individualized treatment in LUAD patients by using ferroptosis-related gene signatures as a potential predictor for prognosis. This indicates a new application method, specifically a new indicator or predictor for clinical use.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

30,988,967

To the best of the authors' knowledge, this study is the first to describe food allergen sensitisation patterns among Omani patients with allergic manifestations. In conjunction with clinical symptoms, the correct interpretation of specific IgE levels is important to diagnose food allergies and make safe decisions about reintroducing foods.

null

New attempt

2/3/2025, 2:49:48 PM

human

New attempt

Finding Novelty - 3.3 New interaction - 3.3.3 New association

{ "category": "3 Finding Novelty - 3.3 New interaction - 3.3.3 New association", "reason": "The sentence claims novelty by stating it is the 'first to describe food allergen sensitisation patterns among Omani patients with allergic manifestations.' This indicates a new association or correlation being identified between food allergen sensitisation patterns and the specific population of Omani patients with allergic manifestations." }

The sentence claims novelty by stating it is the 'first to describe food allergen sensitisation patterns among Omani patients with allergic manifestations.' This indicates a new association or correlation being identified between food allergen sensitisation patterns and the specific population of Omani patients with allergic manifestations.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

22,174,322

Male orthopaedic surgeons have greater intelligence and grip strength than their male anaesthetic colleagues, who should find new ways to make fun of their orthopaedic friends.

Orthopaedic surgeons: as strong as an ox and almost twice as clever? Multicentre prospective comparative study.

BMJ (Clinical research ed.)

2011 Dec 15

1. BMJ. 2011 Dec 15;343:d7506. doi: 10.1136/bmj.d7506. Orthopaedic surgeons: as strong as an ox and almost twice as clever? Multicentre prospective comparative study. Subramanian P(1), Kantharuban S, Subramanian V, Willis-Owen SA, Willis-Owen CA. Author information: (1)North East Thames London Orthopaedic Rotation, Whipps Cross Hospital, Leytonstone, London W11 1NR, UK. [email protected] Comment in BMJ. 2012 Jan 17;344:e413. doi: 10.1136/bmj.e413. Z Orthop Unfall. 2012 Apr;150(2):132-3. OBJECTIVE: To compare the intelligence and grip strength of orthopaedic surgeons and anaesthetists. DESIGN: Multicentre prospective comparative study. SETTING: Three UK district general hospitals in 2011. PARTICIPANTS: 36 male orthopaedic surgeons and 40 male anaesthetists at consultant or specialist registrar grade. MAIN OUTCOME MEASURES: Intelligence test score and dominant hand grip strength. RESULTS: Orthopaedic surgeons had a statistically significantly greater mean grip strength (47.25 (SD 6.95) kg) than anaesthetists (43.83 (7.57) kg). The mean intelligence test score of orthopaedic surgeons was also statistically significantly greater at 105.19 (10.85) compared with 98.38 (14.45) for anaesthetists. CONCLUSIONS: Male orthopaedic surgeons have greater intelligence and grip strength than their male anaesthetic colleagues, who should find new ways to make fun of their orthopaedic friends. DOI: 10.1136/bmj.d7506 PMCID: PMC3240683 PMID: 22174322 [Indexed for MEDLINE] Conflict of interest statement: Competing interests: All authors have completed the Unified Competing Interest form at http://www.icmje.org/coi_disclosure.pdf (available on request from the corresponding author) and declare: no support from any organisation for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work. CAW-O works as an independent consultant for Corin Group, a manufacturer of orthopaedic implants.

Not Novelty

2/3/2025, 2:50:08 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence does not introduce any novel ideas, methods, or findings. It appears to be a humorous or anecdotal statement rather than a claim of scientific novelty. There are no strong indicators of novelty such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own contributions." }

The sentence does not introduce any novel ideas, methods, or findings. It appears to be a humorous or anecdotal statement rather than a claim of scientific novelty. There are no strong indicators of novelty such as 'first,' 'novel,' 'innovation,' or 'new' that refer to the authors' own contributions.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

37,951,900

Neck pain secondary to cervical facet joint disease is prevalent and RFA of the CMBN is a validated treatment for relieving it. The conventional parallel technique can be technically challenging, and it can be associated with adverse effects while the newer end-on approach has the potential of being a simpler technique with less adverse effects. This trial will be the first non-inferiority study to compare the clinical efficacy of the end-on approach against the conventional parallel approach for RFN of CMBN in patients with chronic neck pain due to cervical facet joint disease.

null

Concept Novelty - New attempt

2/3/2025, 2:50:16 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The text explicitly claims novelty by stating 'This trial will be the first non-inferiority study to compare the clinical efficacy of the end-on approach against the conventional parallel approach for RFN of CMBN in patients with chronic neck pain due to cervical facet joint disease.' The use of 'first' indicates a new attempt in the research content." }

The text explicitly claims novelty by stating 'This trial will be the first non-inferiority study to compare the clinical efficacy of the end-on approach against the conventional parallel approach for RFN of CMBN in patients with chronic neck pain due to cervical facet joint disease.' The use of 'first' indicates a new attempt in the research content.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,056,285

Celf1 disruption is responsible for a blockage of spermiogenesis both in adults and in prepubertal males. Hence, the spermiogenesis defects found in Celf1-inactivated adults appear from the first wave of spermiogenesis. The disruption of Celf1 gene is also responsible for a fully penetrant delayed first wave of spermatogenesis, and a delay of steroidogenesis may be the cause for the delay of germ cells differentiation.

null

Not Novelty

2/3/2025, 2:52:45 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not explicitly claim novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the authors' own contributions. It describes findings related to the disruption of the Celf1 gene and its effects on spermiogenesis and spermatogenesis, but does not indicate that these findings are novel or unprecedented. Therefore, it is classified as '4 Not Novelty' as it summarizes existing knowledge without introducing new concepts, methods, or findings." }

The provided text does not explicitly claim novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the authors' own contributions. It describes findings related to the disruption of the Celf1 gene and its effects on spermiogenesis and spermatogenesis, but does not indicate that these findings are novel or unprecedented. Therefore, it is classified as '4 Not Novelty' as it summarizes existing knowledge without introducing new concepts, methods, or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,028,874

We have provided the first evidence that TAD therapy ameliorates circulating inflammatory cytokines and chemokines in a diabetic animal model while improving fasting glucose levels and reducing infarct size following ischemia-reperfusion injury in the heart.

null

Finding Novelty - 3.4 Other new finding

2/3/2025, 2:53:05 PM

openai

null

Finding Novelty - 3.4 Other new finding

{ "category": "3 Finding Novelty - 3.4 Other new finding", "reason": "The sentence claims to provide the first evidence of TAD therapy's effects on inflammatory cytokines, chemokines, fasting glucose levels, and infarct size in a diabetic animal model. This suggests a new finding in terms of the effects of TAD therapy, which fits under the category of discovering new results and knowledge." }

The sentence claims to provide the first evidence of TAD therapy's effects on inflammatory cytokines, chemokines, fasting glucose levels, and infarct size in a diabetic animal model. This suggests a new finding in terms of the effects of TAD therapy, which fits under the category of discovering new results and knowledge.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

28,056,030

Our findings on simeprevir plus PR therapy shortened to 12 weeks in patients with HCV GT4 infection with favourable baseline characteristics and displaying early on-treatment virologic response are encouraging. No new safety signals were associated with simeprevir plus PR in this study.

null

Not Novelty

2/3/2025, 2:53:18 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion does not explicitly claim any novel contributions using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to their own research. It summarizes findings and safety observations without introducing new concepts, methods, or findings." }

The conclusion does not explicitly claim any novel contributions using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to their own research. It summarizes findings and safety observations without introducing new concepts, methods, or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

18,509,538

This is the first study to provide a framework to guide general practice planning for pandemic influenza. The framework helped identify critical shortcomings in available plans. Engaging general practice effectively in planning is challenging, particularly where governance structures for primary health care are weak. We identify implications for practice and for research.

null

Concept Novelty - 1.1 New attempt

2/3/2025, 2:53:42 PM

openai

null

Concept Novelty - 1.1 New attempt

{ "category": "1 Concept Novelty - 1.1 New attempt", "reason": "The sentence explicitly states 'This is the first study to provide a framework to guide general practice planning for pandemic influenza,' indicating that the study is introducing a new attempt in the field by providing a novel framework that has not been explored before." }

The sentence explicitly states 'This is the first study to provide a framework to guide general practice planning for pandemic influenza,' indicating that the study is introducing a new attempt in the field by providing a novel framework that has not been explored before.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

19,292,886

From these data, we conclude that CD98hc is expressed in RCCs, whereby the extent of expression is likely to correlate directly with grade of malignancy. In pRCCs, CD98hc might represent a novel and reliable marker for type II pRCC.

null

Finding Novelty - 3.2 New property/feature - 3.2.3 New marker

2/3/2025, 2:54:35 PM

openai

null

Finding Novelty - 3.2 New property/feature - 3.2.3 New marker

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.3 New marker", "reason": "The conclusion suggests that CD98hc might represent a novel and reliable marker for type II pRCC, indicating the identification of a new biological marker. The use of 'novel' directly refers to the authors' contribution in identifying this new marker, which fits the criteria for finding novelty under the sub-category of new property/feature." }

The conclusion suggests that CD98hc might represent a novel and reliable marker for type II pRCC, indicating the identification of a new biological marker. The use of 'novel' directly refers to the authors' contribution in identifying this new marker, which fits the criteria for finding novelty under the sub-category of new property/feature.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

32,685,450

These hub lncRNAs and mRNAs were potential prognostic biomarkers for the meniscus degeneration of KOA. Further studies are required to validate these new biomarkers and better understand the pathological process of the meniscus degeneration of KOA.

null

New marker

2/3/2025, 2:55:26 PM

human

New marker

Not Novelty

{ "category": "4 Not Novelty", "reason": "The text mentions 'new biomarkers,' but it does not explicitly claim that these biomarkers are a novel discovery made by the authors. Instead, it suggests that further studies are needed to validate them, indicating that the novelty is not established in this work. Therefore, it does not meet the criteria for novelty classification." }

The text mentions 'new biomarkers,' but it does not explicitly claim that these biomarkers are a novel discovery made by the authors. Instead, it suggests that further studies are needed to validate them, indicating that the novelty is not established in this work. Therefore, it does not meet the criteria for novelty classification.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

7,476,610

The epidemiology of MRSA in WA is changing rapidly, with increases in both the numbers of notifications and the proportion from country regions. A new strain of MRSA (WA MRSA) that is less resistant to antibiotics than imported MRSA has emerged and is threatening the State's success in preventing establishment of MRSA in its hospitals.

null

New genus and species

2/3/2025, 2:56:06 PM

human

New genus and species

Finding Novelty - 3.1 New object - 3.1.1 New substance

{ "category": "3 Finding Novelty - 3.1 New object - 3.1.1 New substance", "reason": "The text mentions the emergence of a 'new strain of MRSA (WA MRSA)' which is a new object in the form of a biological substance. This indicates a novel finding in the context of the study, as it identifies a previously unknown strain of MRSA." }

The text mentions the emergence of a 'new strain of MRSA (WA MRSA)' which is a new object in the form of a biological substance. This indicates a novel finding in the context of the study, as it identifies a previously unknown strain of MRSA.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

25,885,044

Together, our results suggest for the first time that the genetic variants in NTRK2 may regulate eGFR.

null

Finding Novelty - 3.3 New interaction - 3.3.3 New association

2/3/2025, 2:56:56 PM

openai

null

Finding Novelty - 3.3 New interaction - 3.3.3 New association

{ "category": "3 Finding Novelty - 3.3 New interaction - 3.3.3 New association", "reason": "The sentence claims novelty by stating 'for the first time' and suggests a new association between genetic variants in NTRK2 and the regulation of eGFR. This fits the category of discovering a new correlation or association among variables." }

The sentence claims novelty by stating 'for the first time' and suggests a new association between genetic variants in NTRK2 and the regulation of eGFR. This fits the category of discovering a new correlation or association among variables.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

28,862,170

With the application of NT springs in dogs that allowed posterior tethering in various directions, lumbar spinal deformity was achieved in three planes: coronal, sagittal, and transverse planes. Notably, the lumbar spine in surgically treated dogs developed lordoscoliosis with obvious rotation and the curves mimic AIS three dimensionally well. This method allows lumbar scoliosis to develop without deep dissection of muscle and maintains the essential anatomical elements along the spinal curve. Moreover, the spinal growth modulation technique could yield information that would provide a basis for developing novel early-stage treatments for children with scoliosis.

null

Method and Material Novelty - 2.2 New application method - 2.2.1 New Therapy

2/3/2025, 2:57:12 PM

openai

New Therapy

Method and Material Novelty - 2.2 New application method - 2.2.1 New Therapy

{ "category": "2 Method and Material Novelty - 2.2 New application method - 2.2.1 New Therapy", "reason": "The conclusion describes a novel application method involving the use of NT springs in dogs to achieve lumbar spinal deformity in three planes, which mimics AIS. This method is highlighted as a potential basis for developing new early-stage treatments for children with scoliosis, indicating a novel therapeutic strategy." }

The conclusion describes a novel application method involving the use of NT springs in dogs to achieve lumbar spinal deformity in three planes, which mimics AIS. This method is highlighted as a potential basis for developing new early-stage treatments for children with scoliosis, indicating a novel therapeutic strategy.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

24,015,309

The present study, the first cohort study to examine the association of hypopharyngeal and laryngeal cancer incidence rates with bidi smoking in South Asia, clearly showed dose-response relationships between those cancer risks and bidi smoking; larger amounts of bidi smoked a day and longer durations of bidi smoking increased the incidence rates of those cancers. Tobacco chewing was found not related to the risk of hypopharynx or larynx cancer.

null

Concept Novelty - New attempt

2/3/2025, 2:57:54 PM

openai

null

Concept Novelty - New attempt

{ "category": "1 Concept Novelty - New attempt", "reason": "The sentence explicitly states that this is the 'first cohort study' to examine the association of hypopharyngeal and laryngeal cancer incidence rates with bidi smoking in South Asia. This indicates a new attempt in the research field, as it explores a new scientific research content that has not been explored before." }

The sentence explicitly states that this is the 'first cohort study' to examine the association of hypopharyngeal and laryngeal cancer incidence rates with bidi smoking in South Asia. This indicates a new attempt in the research field, as it explores a new scientific research content that has not been explored before.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

32,041,657

This is, to our knowledge, the first randomized, placebo-controlled, double-blind clinical trial assessing the effectiveness of MTX and LEF combination therapy in patients with PsA. The study will provide important information for treatment strategies and treatment recommendations.

null

Concept Novelty - 1.1 New attempt

2/3/2025, 2:58:03 PM

openai

null

Concept Novelty - 1.1 New attempt

{ "category": "1 Concept Novelty - 1.1 New attempt", "reason": "The sentence explicitly claims novelty by stating it is the 'first randomized, placebo-controlled, double-blind clinical trial' assessing a specific combination therapy in patients with PsA. This indicates a new attempt in the research field." }

The sentence explicitly claims novelty by stating it is the 'first randomized, placebo-controlled, double-blind clinical trial' assessing a specific combination therapy in patients with PsA. This indicates a new attempt in the research field.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

16,398,153

Rehabilitation treatment of patients with severe traumatic brain injury is suggested in centers, where special team is available for the patients with multifunctional impairments. Nowadays, only one third of these patients are treated by rehabilitation centers in Hungary. Establishing new centers, development of the existing units, improvement the outpatient or community based rehabilitation facilities are suggested in order to improve the rehabilitation outcome of patients with severe traumatic brain injury.

null

Not novelty

2/3/2025, 2:58:30 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The text discusses recommendations for improving rehabilitation treatment for patients with severe traumatic brain injury in Hungary. It suggests establishing new centers and improving existing facilities, but it does not introduce any novel ideas, methods, or findings. The mention of 'new centers' refers to the establishment of additional facilities rather than a novel concept or method in the biomedical field. Therefore, it is classified as '4 Not novelty'." }

The text discusses recommendations for improving rehabilitation treatment for patients with severe traumatic brain injury in Hungary. It suggests establishing new centers and improving existing facilities, but it does not introduce any novel ideas, methods, or findings. The mention of 'new centers' refers to the establishment of additional facilities rather than a novel concept or method in the biomedical field. Therefore, it is classified as '4 Not novelty'.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

18,072,896

The Christmas and New Year period is the busiest time of year for NSW EDs. However, only some of the additional holiday visits can be attributed to GP-type visits. Improving access to GPs, but also to broader hospital and community-based health care services over the holiday period, should be considered for managing the excess demand.

null

Not Novelty

2/3/2025, 2:58:49 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The provided text does not introduce any novel ideas, methods, or findings. It discusses existing knowledge about the increased demand in emergency departments during the holiday period and suggests improving access to healthcare services. There are no claims of novelty or new contributions in the research work." }

The provided text does not introduce any novel ideas, methods, or findings. It discusses existing knowledge about the increased demand in emergency departments during the holiday period and suggests improving access to healthcare services. There are no claims of novelty or new contributions in the research work.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

30,557,984

Our case is remarkable owing to the unusually early (<1 hour) occurrence of STEMI after i.v. rtPA administration. A third-degree atrioventricular block after thrombolysis for AIS could signal a STEMI onset. New and ongoing trials are assessing whether adjunct administration of direct thrombin inhibitors of rtPA in the first 24 hours after thrombolysis for AIS can prevent early recurrent ischemic events.

null

Not novelty

2/3/2025, 2:59:03 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The text does not explicitly claim novelty in the research work using strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' in a way that directly refers to their own novel contributions. It describes a case and ongoing trials without introducing new concepts, methods, or findings." }

The text does not explicitly claim novelty in the research work using strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' in a way that directly refers to their own novel contributions. It describes a case and ongoing trials without introducing new concepts, methods, or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,822,618

We assume that after the interaction of the selected amino acids 10 % L-arginin or 10 % L-taurin with the double combination of antiglaucomatics (Trusopt and Xalatan, COSOPT or Timoptol and Xalatan) a new substance was formed. The effect of this substance is not separate or additive but acts as a newly formed substance. In vivo, it is only a weak interaction with the free amino acids of the conjunctival sac and the antiglaucomatics. The amino acids interacted in vitro with the double combination of antiglaucomatics resulting in a new "bio-antiglaucomatic" better penetrating into the target area. This new substance was responsible for a more significant decrease and regulation IOP after the mixture application compared to the antiglaucomatics alone (Fig. 1, Ref. 23).

null

Finding Novelty - 3.1 New object - 3.1.1 New substance

2/3/2025, 2:59:47 PM

openai

null

Finding Novelty - 3.1 New object - 3.1.1 New substance

{ "category": "3 Finding Novelty - 3.1 New object - 3.1.1 New substance", "reason": "The conclusion describes the formation of a new substance resulting from the interaction of amino acids with antiglaucomatics. This is classified as a new object, specifically a new substance, as it highlights the discovery of a previously unidentified compound with distinct properties and effects." }

The conclusion describes the formation of a new substance resulting from the interaction of amino acids with antiglaucomatics. This is classified as a new object, specifically a new substance, as it highlights the discovery of a previously unidentified compound with distinct properties and effects.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

22,693,564

STC1 activates a novel anti-oxidant pathway in cardiac myocytes through induction of UCP3, and may play an important role in suppressing ROS in the heart under normal physiologic conditions and ameliorate the deleterious effects of Ang II-mediated cardiac injury. Importantly, our data point to a critical role for the mitochondria in regulating ROS generation in response to Ang II.

null

Finding Novelty - 3.3 New interaction - 3.3.1 New pathway

2/3/2025, 2:59:53 PM

openai

null

Finding Novelty - 3.3 New interaction - 3.3.1 New pathway

{ "category": "3 Finding Novelty - 3.3 New interaction - 3.3.1 New pathway", "reason": "The sentence claims the activation of a 'novel anti-oxidant pathway' in cardiac myocytes by STC1, which indicates the discovery of a new interaction or relationship among known objects, specifically a new pathway. The use of 'novel' directly refers to their own contribution, classifying it under finding novelty." }

The sentence claims the activation of a 'novel anti-oxidant pathway' in cardiac myocytes by STC1, which indicates the discovery of a new interaction or relationship among known objects, specifically a new pathway. The use of 'novel' directly refers to their own contribution, classifying it under finding novelty.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,775,773

The results of this meta-analysis support the therapeutic efficacy of adjuvant interferon alpha for the treatment of people with high-risk (AJCC TNM stage II-III) cutaneous melanoma in terms of both disease-free survival and, though to a lower extent, overall survival. Interferon is also valid as a reference treatment in RCTs investigating new therapeutic agents for the adjuvant treatment of this participant population. Further investigation is required to select people who are most likely to benefit from this treatment.

null

Not Novelty

2/3/2025, 3:00:34 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion summarizes the therapeutic efficacy of adjuvant interferon alpha for treating high-risk cutaneous melanoma, which is existing knowledge. It does not introduce any novel ideas, methods, or findings. The mention of 'new therapeutic agents' refers to future research directions rather than a novel contribution of the current study." }

The conclusion summarizes the therapeutic efficacy of adjuvant interferon alpha for treating high-risk cutaneous melanoma, which is existing knowledge. It does not introduce any novel ideas, methods, or findings. The mention of 'new therapeutic agents' refers to future research directions rather than a novel contribution of the current study.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

10,796,303

Implications for practice. Methylxanthines might increase the chances of successful extubation of some preterm infants but the results of this meta-analysis do not allow firm recommendations to be made for clinical practice. One trial suggests that this benefit is principally in infants of extremely low birth weight extubated in the first week. There are no trial data to support the routine use of methylxanthines for the extubation of infants with a birth weight over 1000 gms or those that are older than one week. Implications for research. Further trials are required comparing methylxanthines with placebo for extubation of very preterm infants. There is a need to stratify infants by gestational age (a better indicator of immaturity) rather than birth weight in future studies. Caffeine, with its wider therapeutic margin (Blanchard 1992) would be the better treatment to evaluate against placebo. Side effects and neuro-developmental status at follow up should be included in as outcomes.

null

Not novelty

2/3/2025, 3:00:54 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The provided text does not introduce any novel ideas, methods, or findings. It summarizes existing knowledge and suggests implications for practice and research without claiming any new contributions or discoveries. The text discusses the need for further trials and considerations for future studies, but it does not present any original research or findings that would classify it as novel." }

The provided text does not introduce any novel ideas, methods, or findings. It summarizes existing knowledge and suggests implications for practice and research without claiming any new contributions or discoveries. The text discusses the need for further trials and considerations for future studies, but it does not present any original research or findings that would classify it as novel.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

24,794,369

This preliminary assessment did not find an increased risk of adverse events among women who received Tdap vaccine during pregnancy or their infants. For secondary outcomes, maternal immunization with Tdap resulted in high concentrations of pertussis antibodies in infants during the first 2 months of life and did not substantially alter infant responses to DTaP. Further research is needed to provide definitive evidence of the safety and efficacy of Tdap immunization during pregnancy.

null

Not novelty

2/3/2025, 3:01:01 PM

openai

null

Not novelty

{ "category": "4 Not novelty", "reason": "The conclusion summarizes the findings of the study regarding the safety and efficacy of Tdap immunization during pregnancy. It does not introduce any novel ideas, methods, or findings. The mention of 'further research is needed' indicates a continuation of existing research rather than a novel contribution. There are no explicit claims of novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the study's contributions." }

The conclusion summarizes the findings of the study regarding the safety and efficacy of Tdap immunization during pregnancy. It does not introduce any novel ideas, methods, or findings. The mention of 'further research is needed' indicates a continuation of existing research rather than a novel contribution. There are no explicit claims of novelty using terms like 'first,' 'novel,' 'innovation,' or 'new' in relation to the study's contributions.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

20,445,638

Cognitive decline and Alzheimer’s disease are major causes of morbidity and mortality worldwide and are substantially burdensome to the affected persons, their caregivers, and society in general. Extensive research over the past 20 years has provided important insights on the nature of Alzheimer’s disease and cognitive decline and the magnitude of the problem. Nevertheless, there remain important and formidable challenges in conducting research on these diseases, particularly in the area of prevention. Currently, firm conclusions cannot be drawn about the association of any modifiable risk factor with cognitive decline or Alzheimer’s disease. Highly reliable consensus-based diagnostic criteria for cognitive decline, mild cognitive impairment, and Alzheimer’s disease are lacking, and available criteria have not been uniformly applied. Evidence is insufficient to support the use of pharmaceutical agents or dietary supplements to prevent cognitive decline or Alzheimer’s disease. We recognize that a large amount of promising research is under way; these efforts need to be increased and added to by new understandings and innovations (as noted in our recommendations for future research). For example, ongoing studies including (but not limited to) studies on antihypertensive medications, omega-3 fatty acids, physical activity, and cognitive engagement may provide new insights into the prevention or delay of cognitive decline or Alzheimer’s disease. This important research needs to be supplemented by further studies. Large-scale population-based studies and randomized controlled trials (RCTs) are critically needed to investigate strategies to maintain cognitive function in individuals at risk for decline, to identify factors that may delay the onset of Alzheimer’s disease among persons at risk, and to identify factors that may slow the progression of Alzheimer’s disease among persons in whom the condition is already diagnosed.

null

Not Novelty

2/3/2025, 3:01:07 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion does not explicitly claim any novel contributions made by the authors themselves. It discusses the current state of research, acknowledges ongoing studies, and emphasizes the need for further research. The mention of 'new understandings and innovations' refers to future research directions rather than specific novel contributions made by the authors in this study." }

The conclusion does not explicitly claim any novel contributions made by the authors themselves. It discusses the current state of research, acknowledges ongoing studies, and emphasizes the need for further research. The mention of 'new understandings and innovations' refers to future research directions rather than specific novel contributions made by the authors in this study.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

25,856,858

The novel syringe facilitates cell transplantation across the subretina and extravascular spaces of the choroid using a minimally-invasive procedure. Human BM-MSC transplantation using this system ameliorates retinal degeneration in the animal model. This new transplantation system may increase the therapeutic effect of other cell-based therapies and therapeutic agents. This study is expected to lead directly to phase I clinical trials for autologous hBM-MSCs transplantation in patients with retinal degeneration.

null

Method and Material Novelty - 2.2 New application method - 2.2.3 New tool/device

2/3/2025, 3:01:13 PM

openai

null

Method and Material Novelty - 2.2 New application method - 2.2.3 New tool/device

{ "category": "2 Method and Material Novelty - 2.2 New application method - 2.2.3 New tool/device", "reason": "The conclusion describes a 'novel syringe' as a new tool facilitating cell transplantation in a minimally-invasive manner. This indicates the development of a new device, which is a novel contribution in the context of the study." }

The conclusion describes a 'novel syringe' as a new tool facilitating cell transplantation in a minimally-invasive manner. This indicates the development of a new device, which is a novel contribution in the context of the study.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

25,058,505

The studies suggest that in some cases ALTs may reduce costs, though little data were identified and what there were was of poor quality. Methods to capture quality of life gains were not used, therefore potential effects on health and wellbeing may be missed. Further research is required using newer developments such as the capabilities approach. High quality studies assessing the cost-effectiveness of ALTs for ageing in place are required before robust conclusion on their use can be drawn.

null

Not Novelty

2/3/2025, 3:01:18 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion does not explicitly claim any novel contributions by the authors. It discusses the need for further research and mentions existing gaps in the data and methods, but does not introduce new ideas, methods, or findings. The mention of 'newer developments' refers to existing concepts rather than novel contributions by the authors." }

The conclusion does not explicitly claim any novel contributions by the authors. It discusses the need for further research and mentions existing gaps in the data and methods, but does not introduce new ideas, methods, or findings. The mention of 'newer developments' refers to existing concepts rather than novel contributions by the authors.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

25,003,827

Through a systematic case-control study of microRNA binding site SNPs, we identified a new breast cancer risk variant rs8752 in HPGD in Chinese women. Further studies are warranted to investigate the underling mechanism for this association.

null

Finding Novelty - 3.2 New property/feature - 3.2.4 New risk variant

2/3/2025, 3:01:24 PM

openai

null

Finding Novelty - 3.2 New property/feature - 3.2.4 New risk variant

{ "category": "3 Finding Novelty - 3.2 New property/feature - 3.2.4 New risk variant", "reason": "The sentence explicitly mentions the identification of a 'new breast cancer risk variant rs8752 in HPGD in Chinese women,' which falls under the category of discovering a new genetic variant linked to disease risk. This is a novel finding as it introduces a previously unidentified risk variant associated with breast cancer." }

The sentence explicitly mentions the identification of a 'new breast cancer risk variant rs8752 in HPGD in Chinese women,' which falls under the category of discovering a new genetic variant linked to disease risk. This is a novel finding as it introduces a previously unidentified risk variant associated with breast cancer.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,543,569

We found no evidence of a difference in mortality, 'clinically significant' or 'severe bleeding', transfusion reactions or adverse events between pathogen-reduced and standard platelets. For a range of laboratory outcomes the results indicated evidence of some benefits for standard platelets over pathogen-reduced platelets. These conclusions are based on data from 1422 patients included in 10 trials. Results from ongoing or new trials are required to determine if there are clinically important differences in bleeding risk between pathogen-reduced platelet transfusions and standard platelet transfusions. Given the variability in trial design, bleeding assessment and quality of outcome reporting, it is recommended that future trials apply standardised approaches to outcome assessment and follow-up, including safety reporting.

null

Not Novelty

2/3/2025, 3:01:28 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The conclusion summarizes the findings of existing trials and suggests the need for future research without introducing any novel ideas, methods, or findings. The mention of 'new trials' refers to future research rather than a novel contribution in the current study." }

The conclusion summarizes the findings of existing trials and suggests the need for future research without introducing any novel ideas, methods, or findings. The mention of 'new trials' refers to future research rather than a novel contribution in the current study.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

8,086,904

An increase in the length of the hip axis in elderly women in New Zealand during the past 40 years has occurred which is large enough to account for the increase in the age adjusted rate of hip fractures during those years.

null

Not Novelty

2/3/2025, 3:01:32 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence describes an observed trend over time regarding hip axis length and hip fracture rates in elderly women in New Zealand. It does not introduce any novel ideas, methods, or findings, nor does it use terms like 'first,' 'novel,' 'innovation,' or 'new' to claim novelty. It summarizes an existing observation rather than presenting new research contributions." }

The sentence describes an observed trend over time regarding hip axis length and hip fracture rates in elderly women in New Zealand. It does not introduce any novel ideas, methods, or findings, nor does it use terms like 'first,' 'novel,' 'innovation,' or 'new' to claim novelty. It summarizes an existing observation rather than presenting new research contributions.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

27,611,434

This is the first report focusing on optic neuropathy in a cohort of complex DR-TB patients, including patients co-infected with HIV, receiving linezolid-containing regimens. In our study, one out of four patients on linezolid had at least one episode of ocular complaints; therefore, systematic monitoring of patients by primary physicians/nurses, and access to specialized diagnostic-services by specialists are needed. As linezolid will be increasingly added to treatment regimens of DR-TB patients, programmes should allocate adequate resources for early diagnosis, prevention and management of this disabling adverse event.

null

New attempt

2/3/2025, 3:01:47 PM

human

New attempt

New case

{ "category": "3.1.6 New case", "reason": "The text explicitly mentions 'This is the first report focusing on optic neuropathy in a cohort of complex DR-TB patients, including patients co-infected with HIV, receiving linezolid-containing regimens.' This indicates the identification or documentation of a newly diagnosed patient group with a specific condition, which aligns with the classification of a 'New case' under 'New object' in the taxonomy." }

The text explicitly mentions 'This is the first report focusing on optic neuropathy in a cohort of complex DR-TB patients, including patients co-infected with HIV, receiving linezolid-containing regimens.' This indicates the identification or documentation of a newly diagnosed patient group with a specific condition, which aligns with the classification of a 'New case' under 'New object' in the taxonomy.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

23,451,966

Novel HCV transmission routes have emerged in Victoria. These data reinforce the need for targeted testing and prevention strategies among HIV-infected MSM.

null

Not Novelty

2/3/2025, 3:01:53 PM

openai

null

Not Novelty

{ "category": "4 Not Novelty", "reason": "The sentence does not explicitly claim novelty in the research work using strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' in relation to their own contributions. It mentions 'novel HCV transmission routes,' but this does not refer to a novel contribution by the authors themselves. Instead, it summarizes existing knowledge or findings without introducing new ideas, methods, or findings." }

The sentence does not explicitly claim novelty in the research work using strong indicators such as 'first,' 'novel,' 'innovation,' or 'new' in relation to their own contributions. It mentions 'novel HCV transmission routes,' but this does not refer to a novel contribution by the authors themselves. Instead, it summarizes existing knowledge or findings without introducing new ideas, methods, or findings.

null

prompt-v2.1.txt

taxonomy-v2.2.txt

Datasets:

clinicalnlplab
/

NovelTax

Biomedical Novelty Claim Corpus (Sample)

🔍 Overview

📦 Current Release

📄 Citation