Hi all,

I have a question regarding coding regions in bacterial genomes: **can genes be encoded on both strands like this ?**

![enter image description here][1]


  [1]: /media/images/fceb469c-9a40-47f9-969b-fdce9ddb


**If so, which one is considered as the sense strand ?**

Thank you so much for your help!

yes, for example ryeA/ryeB on E Coli K12:

[link to NCBI view][1]


  [1]: https://www.ncbi.nlm.nih.gov/nuccore/48994873?report=graph&tracks=[key:sequence_track,name:Sequence,display_name:Sequence,id:STD649220238,annots:Sequence,ShowLabel:false,ColorGaps:false,shown:true,order:1][key:gene_model_track,name:Genes,display_name:Genes,id:STD3194982005,annots:Unnamed,Options:MergeAll,CDSProductFeats:false,NtRuler:true,AaRuler:true,HighlightMode:2,ShowLabel:true,shown:true,order:4][key:feature_track,name:Repeat%20region,display_name:Repeat%20region,id:STD3463812800,subkey:repeat_region,annots:Unnamed,shown:true,order:5]&assm_context=GCA_000005845.1&v=1920965:1921462&c=C0C0C0&select=null&slim=0


> If so, which one is considered as the sense strand ?

I think it's meaningless 