Hi,

I am trying to analyze a GSE that was performed on affymetrix HT HG-U133+ PM Array Plate [GPL13158][1]

But I cannot find the corresponding annotation package on bioconductor.

Affymetrix website is of no use, return a 404 error when selecting the array.

If anyone has experience with this array and know how to map gene name to probe name, I would be glad to have some help

Thanks

  [1]: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL13158
Oh yeh, some of those links to Affymetrix pages will be broken due to [I believe] the merger between ThermoFisher and Affymetrix. You can now find technical information on either or both websites, like, for example: <a href="http://www.affymetrix.com/support/technical/byproduct.affx?product=ht_hg-u133_pm_ap">HT HG-U133+ PM Array Plate - Support Materials</a>.

The *HT_HG-U133_Plus_PM* is merely a modified version of the original U133 - it has no mismatch (MM) probes and has a few other modifications.

There is a Bioconductor package <a href="https://bioconductor.org/packages/release/data/annotation/html/pd.ht.hg.u133.plus.pm.html">HERE</a>. You may have to install it from the source tar.gz.

If not the Bioconductor package, then just download the annotation table at the bottom of the GEO page (<a href="https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL13158">GPL13158</a>), and load that manually into the fdata slot of the *ExpressionSet* object.

Kevin