I have ~70k dbSNP ids I need to get Exac minor allele counts and minor allele frequencies for.

Supposedly Exac provides this information for variants, but I can't find it, either in the JSON results obtainable through http://exac.hms.harvard.edu/rest or through Exac's web interface.

(BTW, the information needs to be from Exac, to be procedurally consistent with other annotations I'm working with.)


Hello,

you can use the [dbsnp endpoint][1] from Exac's REST-API, or the
[variation endpoint][2] from ensembl's REST-API. In both cases you have
to parse the json for the allele frequencys to find out which allele is
the minor one and what it's value.

fin swimmer


  [1]: http://exac.hms.harvard.edu/#rest-dbsnp
  [2]: http://rest.ensembl.org/documentation/info/variation_id
