Hi All,

I am using 20/20 plus algorithms for the identification of driver mutations in my sample. while creating Simulated features I am facing an error.

    rule simFeatures:
        input: output_soma_freebayes/simulated_summary/chasm_sim_summary3.txt, output_soma_freebayes/simulated_summary/oncogene_sim3.txt, output_soma_freebayes/simulated_summary/tsg_sim3.txt
        output: output_soma_freebayes/simulated_summary/simulated_features3.txt
        jobid: 11
        wildcards: iter=3
    
    python `which 2020plus.py` features   -s output_soma_freebayes/simulated_summary/chasm_sim_summary3.txt --tsg-test output_soma_freebayes/simulated_summary/tsg_sim3.txt -og-test output_soma_freebayes/simulated_summary/oncogene_sim3.txt   -o output_soma_freebayes/simulated_summary/simulated_features3.txt
    which: no 2020plus.py in (/home/ateeqanees/anaconda3/bin:/home/ateeqanees/miniconda3/envs/2020plus/bin:/home/ateeqanees/miniconda3/condabin:/home/ateeqanees/anaconda3/bin:/usr/lib64/qt-3.3/bin:/usr/local/bin:/usr/local/sbin:/usr/bin:/usr/sbin:/bin:/sbin:/home/ateeqanees/.local/bin:/home/ateeqanees/bin)
    ***python: can't open file 'features': [Errno 2] No such file or directory***
    Error in job simFeatures while creating output file output_soma_freebayes/simulated_summary/simulated_features3.txt.
    RuleException:
    CalledProcessError in line 202 of /home/ateeqanees/Desktop/20_20/2020plus-1.2.2/Snakefile:
    Command 'python `which 2020plus.py` features   -s output_soma_freebayes/simulated_summary/chasm_sim_summary3.txt --tsg-test output_soma_freebayes/simulated_summary/tsg_sim3.txt -og-test output_soma_freebayes/simulated_summary/oncogene_sim3.txt   -o output_soma_freebayes/simulated_summary/simulated_features3.txt' returned non-zero exit status 2.
      File "/home/ateeqanees/Desktop/20_20/2020plus-1.2.2/Snakefile", line 202, in __rule_simFeatures
      File "/home/ateeqanees/miniconda3/envs/2020plus/lib/python3.6/concurrent/futures/thread.py", line 56, in run
    Will exit after finishing currently running jobs.
    Exiting because a job execution failed. Look above for error message

I am not sure how to solve this I am referring to the [Tutorial Documentation from here][1].
Please let me know how to solve this issue.


  [1]: https://2020plus.readthedocs.io/en/latest/tutorial.html
I think the 2020plus.py scripts is not found in your current PATH. Enter something like this into your command line or .bash_rc file:

export PATH=$PATH:/path/to/2020plus

Where /path/to/2020plus is where you downloaded 2020plus on your system. If successful you should be able to type `which 2020plus.py` into a terminal and it will print out the correct path to the 2020plus.py script. See [here][1] for more details. Hopefully this fixes your issue.


  [1]: https://2020plus.readthedocs.io/en/latest/installation.html#check-your-path-variable