Hi all,

Im using Hisat2 to align RNAseq data and encountering following error:

    (ERR): hisat2-align died with signal 8 (FPE) (core dumped)


using following command

    ./hisat2 --mp 0,0 --np 0 --pen-noncansplice 10000000 --min-intronlen 20 --max-intronlen 10000 --novel-splicesite-outfile /data/memona/hisat2-2.1.0/result/ --rna-strandness RF --dta -p64 --summary-file -x /data/memona/hisat2-2.1.0/hisat_index -1 /data/memona/Trimmomatic-0.36/SRR9591_E_1P.fq -2 /data/memona/Trimmomatic-0.36/SRR9591_E_2P.fq -S /data/memona/hisat2-2.1.0/result/hisat_align.sam

can anyone kindly suggest possible cause and solution to the problem.

Thanks
Looks like these issues have been already taken care in the recent version. Check your HISAT version using

    hisat2 --version

Update if necessary