I am developing an R package and I plan to eventually upload it to BioConductor. However, after I went over the guidelines, I realized that it seems to be more restricted comparing with the requirement from CRAN. I followed the book: "[R Package][1]" by Hadley Wickham, but I believe this book is designed to help people submit CRAN packages, not too specifically for BioConductor.

Therefore I wonder if there is any special issue I should pay additional attention here. Especially formats I guess. 

Thank you.

  [1]: http://r-pkgs.had.co.nz/
I have a package at Bioconductor and I really appreciated the support during the initial review, where I was asked some improvements of quality that were not too demanding, but still made me learn more about S4 classes. I find the 6-month release schedule to be a good regular reminder, and in the worst case there is now [a procedure to retire packages](https://www.bioconductor.org/developers/package-end-of-life/). New packages can be [submitted through GitHub](https://github.com/Bioconductor/Contributions/blob/master/CONTRIBUTING.md), and it is possible to [push updates via a nice Git-Svn bridge](https://www.bioconductor.org/developers/how-to/git-mirrors/). Lastly, the use of Bioconductor's base S4 classes is not mandatory (but of course comes naturally once one gets more experienced). Altogether, Bioconductor is a brilliant platform and it is worth the effort aiming for it.