Im new to bioinformatics and trying to figure out log 2 FC.. 

i have a log 2 fold values of  a parts of a gene in full sequence which is listed below using micro arrays.
      log2-fold change
	-0.611040
	-0.583231
	-0.495397
	-0.462919
	0.412907
	0.405912 which goes on
	
 
does  negative value mean down regulation and positive valuse mean up regulation ?? like the values with 0 ,1 or -1

 


From [wikipedia][1]:

> In the field of genomics (and more generally in bioinformatics), the modern usage is to define fold change in terms of ratios, and not by the alternative definition.[9][10]
> However, log-ratios are often used for analysis and visualization of fold changes. The logarithm to base 2 is most commonly used,[9][10] as it is easy to
> interpret, e.g. a doubling in the original scaling is equal to a log2
> fold change of 1, a quadrupling is equal to a log2 fold change of 2
> and so on. Conversely, the measure is symmetric when the change
> decreases by an equivalent amount e.g. a halving is equal to a log2
> fold change of −1, a quartering is equal to a log2 fold change of −2
> and so on.

and eg other posts here on Biostars:
https://www.biostars.org/p/101727/


in other words: have you tried googling it first?


  [1]: https://en.wikipedia.org/wiki/Fold_change