Hello,

I've watched a video from YouTube about OMIM. Then I get that OMIM already had more than 3000 disease-associated genes till last year. Now I want to get all of those genes from OMIM to do some experiments.

I think maybe I should use "Gene Map" of OMIM, but I still don't know how to search to get all disease-associated genes.

Do you have any good advice or guide?

Thank you in advance,

naulty
First of all, let's clarify that in OMIM there are two types of IDs:

- the MIM Gene ID refers to genes (.e.g [600276][1])
- the MIM MORBID ID refers to diseases/phenotypes ( e.g. [125310][2])

It is easy to make confusion, because both types of IDs are integer and there is no easy way to tell whether an ID refers to a gene or to a disease. If you look for example at the MORBID ID http://www.omim.org/entry/125310, you will see that it is associated to at least one gene.

To download all the genes, you can use the page posted by Santhilal Subhash, parsing the files morbidmap and genemap in order to get the ids. An alternative is to download them from [Biomart][3], selecting no filters, and the MIM Ids in the Output tab. This will give you a list of all the genes and their association to disease, with the advantage that you can select other output columns to get other information about the genes.

 [1]: http://www.omim.org/entry/600276?search=600276&highlight=600276
 [2]: http://www.omim.org/entry/125310
 [3]: http://central.biomart.org/martwizard/#!/Search_by_database_name?mart=Ensembl%2077%20Genes%20%28WTSI,%20UK%29