Hi,

maybe it's a stupid question, but, are gene symbols supposed to be case sensitive or case insensitive?

E.g. GENE1, gene1, GenE1 represent the same gene?

Thanks
<p>It&#39;ll depend on the organism. Human genes, for example, are always upper case (e.g., &quot;GENE1&quot;), with the exception of ORFs (e.g., C17orf12, which probably doesn&#39;t exist). Mouse genes, on the other hand, have a capitalized first letter and the rest lower case (e.g., &quot;<em>Gene1</em>&quot;, which also needs to be italicized). In neither of those would a gene named &quot;GenE1&quot; exist. Having said that, you may see things like &quot;GenE1&quot; in print, since it&#39;s sometimes easier to see that that means gene family &quot;Gen&quot; subgroup &quot;E&quot; member &quot;1&quot;, though it&#39;s often not technically correct. Technically a drosophila gene could be named &quot;GenE1&quot;, since there&#39;s no strict rule on case (everything after the first letter is normally lower-case, but there&#39;s no &quot;must&quot; in that rule).</p>
