I have downloaded a database from GEO using getGEO and then converted it into ExpressionSets using GDS2eSet. Now I am trying to normalize it using rma. It gives me error :unable to find an inherited method for function ‘probeNames’ for signature ‘"ExpressionSet". Which function I showed use to normalize the expression set ?

    a1<-getGEO('GDS4758',  destdir=".")
    eset<- GDS2eSet(a1, do.log2=TRUE)
    eset1<-rma(eset)
Hi,

the error message resembles one in this [thread][1]. It looks like you should use *different* **rma** function, namely from **oligo** package. You could try `oligo::rma` instead of `rma` (after possible installation of `oligo` library)


  [1]: https://support.bioconductor.org/p/71097/