Hi all,

I'm analysing some microarray data and just calculated p-values using a t-test between 2 conditions (each with 3 replicates; total number of genes 14000). My p-values and adjusted p-values are coming out exactly the same. I've tried both FDR and bonferroni for correction using the p.adjust function in R and the results are the same. Is it possible to have the exact same p-values and adjusted p-values. I'm getting a bit doubtful. Any thoughts.

Thanks!!!


It's impossible to have the same p-value and adjusted p-value after bonferroni correction with 14000 genes. There must be an error with the code at some point, please post it.

Also, you want to use limma rather than directly doing a T-test.