<p>In all RNA-seq analysis applications they talk about the dispersion of a gene. As far as I understood, it is not a variance of the normalized counts for a given gene. It is somehow much more complicated.<br />
<br />
DESeq defines the dispersion as follows:<br />
<img alt="" src="http://cs631431.vk.me/v631431783/dd2/HsNUDO5_1aQ.jpg" style="height:100px; width:300px" /><br />
<br />
But what would a dispersion of 0.19 or a dispersion of 0.80 tell me? Can I still interpret it as a variance of a gene?</p>

<p>https://support.bioconductor.org/p/75260/</p>
