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25498992 | background | Heart failure ( HF ) patients suffer from frequent and repeated hospitalizations , causing a substantial economic burden on society . | 0 |
25498992 | background | Hospitalizations can be reduced considerably by better compliance with self-care . | 1 |
25498992 | background | Home telemonitoring has the potential to boost patients ' compliance with self-care , although the results are still contradictory . | 2 |
25498992 | objective | A randomized controlled trial was conducted in order to study whether the multidisciplinary care of heart failure patients promoted with telemonitoring leads to decreased HF-related hospitalization . | 3 |
25498992 | methods | HF patients were eligible whose left ventricular ejection fraction was lower than @ % , NYHA functional class @ , and who needed regular follow-up . | 4 |
25498992 | methods | Patients in the telemonitoring group ( n = @ ) measured their body weight , blood pressure , and pulse and answered symptom-related questions on a weekly basis , reporting their values to the heart failure nurse using a mobile phone app . | 5 |
25498992 | methods | The heart failure nurse followed the status of patients weekly and if necessary contacted the patient . | 6 |
25498992 | methods | The primary outcome was the number of HF-related hospital days . | 7 |
25498992 | methods | Control patients ( n = @ ) received multidisciplinary treatment according to standard practices . | 8 |
25498992 | methods | Patients ' clinical status , use of health care resources , adherence , and user experience from the patients ' and the health care professionals ' perspective were studied . | 9 |
25498992 | results | Adherence , calculated as a proportion of weekly submitted self-measurements , was close to @ % . | 10 |
25498992 | results | No difference was found in the number of HF-related hospital days ( incidence rate ratio -LSB- IRR -RSB- = @ , P = @ ) , which was the primary outcome . | 11 |
25498992 | results | The intervention group used more health care resources : they paid an increased number of visits to the nurse ( IRR = @ , P < @ ) , spent more time at the nurse reception ( mean difference of @ minutes , P < @ ) , and there was a greater number of telephone contacts between the nurse and intervention patients ( IRR = @ , P < @ for nurse-induced contacts and IRR = @ , P = @ for patient-induced contacts ) . | 12 |
25498992 | results | There were no statistically significant differences in patients ' clinical health status or in their self-care behavior . | 13 |
25498992 | results | The technology received excellent feedback from the patient and professional side with a high adherence rate throughout the study . | 14 |
25498992 | conclusions | Home telemonitoring did not reduce the number of patients ' HF-related hospital days and did not improve the patients ' clinical condition . | 15 |
25498992 | conclusions | Patients in the telemonitoring group contacted the Cardiology Outpatient Clinic more frequently , and on this way increased the use of health care resources . | 16 |
24411490 | objective | Probiotics help maintain balance in composition of the gut microbiota , and have been considered as a potential treatment for obesity . | 0 |
24411490 | objective | This study was conducted in order to assess the effects of probiotics when combined with herbal medicine in treatment of obesity . | 1 |
24411490 | objective | Probiotics were tested for the ability to modulate gut microbiota , gut permeability , and endotoxin level , which may have correlation with factors involved in obesity . | 2 |
24411490 | methods | A randomized , double-blind , placebo controlled study was conducted , in which patients with higher BMI ( > @kg/m ( @ ) ) and waist circumference ( > @cm ) were enrolled and randomly assigned to receive Bofutsushosan with either probiotics or placebo capsules for a period of eight weeks . | 3 |
24411490 | methods | Assessment of body composition parameters , metabolic biomarkers , endotoxin level , gut permeability , and fecal bacteria in stool was performed at baseline and at week @ . | 4 |
24411490 | methods | The study was registered at the Clinical Research Information Service , approved by the Korea National Institute of Health ( KCT@ ) . | 5 |
24411490 | results | Although both groups showed a significant reduction in weight and waist circumference ( p = @ ) , no significant differences in body composition and metabolic markers were observed . | 6 |
24411490 | results | In correlation analysis , change in body composition showed positive correlation with endotoxin level ( r = @ , p < @ for BW ; and r = @ , p < @ for fat mass ) and the population of gut Lactobacillus plantarum ( r = @ , p < @ for BW ; and r = @ , p < @ for BMI ) . | 7 |
24411490 | results | The Gram negative bacterial population in gut also exhibited positive correlation with changes in body composition ( WC ) and total cholesterol level ( r = @ , and @ , for the former and later parameters , respectively , p < @ for both ) . | 8 |
24411490 | results | While , the profile of gut Bifidobacterium breve population showed negative correlation with endotoxin level ( r = -@ , p < @ ) . | 9 |
24411490 | conclusions | Correlations between gut microbiota and change in body composition indicate that probiotics may influence energy metabolism in obesity . | 10 |
24411490 | conclusions | Correlation between endotoxin level and weight reduction indicates that probiotics may play an important role in prevention of endotoxin production , which can lead to gut microbiota dysbiosis associated with obesity . | 11 |
24471516 | objective | The objective of this study is to analyze the effects of a @-week indoor intermittent training program on lung function , physical capacity , body composition and quality of life in children with asthma . | 0 |
24471516 | methods | Participants were randomized in an experimental group ( EG , @ children , age = @ years ) and in a control group ( CG , @ children , age = @ years ) . | 1 |
24471516 | methods | The training program was conducted indoors and consisted of alternating high - and low-intensity stimuli , for three sessions of @min/week , for @ weeks . | 2 |
24471516 | methods | Physical exercise and sports activities were organized to follow the criteria of the American College of Sports Medicine ( @ ) and previous interventions ' studies . | 3 |
24471516 | results | In EG , there was a significant improvement ( p < @ ) in FEV@ , FEV@ , @MWT , handgrip strength , CMJ and flexibility . | 4 |
24471516 | results | Reductions in BMI and fat mass as well as an increase in quality of life were all shown . | 5 |
24471516 | results | The dyspnea index decreased significantly and there were no episodes of EIA . | 6 |
24471516 | results | There is a significant positive correlation ( p < @ ) between the FEV@ with handgrip strength and @MWT and a negative correlation with fat mass . | 7 |
24471516 | conclusions | An indoor intermittent training program with these characteristics has improved lung function , physical capacity , body composition and quality of life in children with asthma . | 8 |
24471516 | conclusions | These training adaptations are particularly relevant for those patients suffering from asthma as a regular physical exercise routine will greatly improve their quality of life . | 9 |
26255514 | objective | To observe the efficacy of catgut implantation at back-shu points in treatment of mild perimenopausal depression of kidney , deficiency and liver stagnation syndrome and analyze its essential function on target symptoms . | 0 |
26255514 | methods | Forty-five cases were randomized into a catgut implantation group ( @ cases ) and atid acupuncture group ( @ cases ) . | 1 |
26255514 | methods | In the catgut implantation group , catguts were implanted at Shenshu ( BL @ ) , Ganshu ( BL @ ) , Xinshu ( BL @ ) , Pishu ( BL @ ) , etc. , once every week . | 2 |
26255514 | methods | In the acupuncture group , the conventional acupuncture was applied to the same acupoints as the catgut implantation group , once every two days . | 3 |
26255514 | methods | The : treatment of @ weeks made one session , and continuous @ sessions were required . | 4 |
26255514 | methods | The efficacy was evaluated in , @ sessions . | 5 |
26255514 | methods | The follow-up started in the @th week . | 6 |
26255514 | methods | Before treatment , after treatment and in the follow-up period , Kupperman score and the total score in Hamilton depression scale ( HAMD ) , as well as the factor score were observed in the patients separately . | 7 |
26255514 | results | Kupperman score , the total HAMD score and the scores in the items of anxiety/somatization , retardation , sleep disorder and cognitive disorder after treatment were all reduced significantly as compared with those before treatment in the two groups ( P < @ , P < @ ) . | 8 |
26255514 | results | In the follow-up period , the difference in Kupperman was not significant in comparison with that after treatment in the catgut implantation : group ( P > @ ) . | 9 |
26255514 | results | The total HAMD score and sleep disorder were reduced significantly as compared with those after treatment in the catgut implantation group ( both P < @ ) ; in the acupuncture group , Kupperman score , the total HAMD score and sleep disorder were all increased as compared with those after treatment ( all P < @ ) . | 10 |
26255514 | results | In ; the catgut implantation group , the total HAMD score was lower than that in the acupuncture group ( P < @ ) , and the scores in the items of retardation and sleep disorder were reduced significantly as compared with those in the acupuncture group ( both P < @ ) . | 11 |
26255514 | conclusions | The catgut implantation at back-shu points alleviates perimenopasual sympton is in patients of mild perimenopausal depression of kidney deficiency and liver stagnation syndrome . | 12 |
26255514 | conclusions | This therapy effectively relieves depressive disorders by regulating the target symptoms such as anxiety / somatization , retardation , sleep disorder and cognitive ' disorder . | 13 |
26255514 | conclusions | The long-term efficacy of this therapy is better than the conventional acupuncture . | 14 |
24952391 | objective | Up to @ % of patients who undergo a percutaneous coronary intervention show some limitation in the use of drug-eluting stents . | 0 |
24952391 | objective | The aim of this study was to evaluate if titanium-nitride-oxide-coated stents could be a good alternative to everolimus-eluting stents in diabetic patients . | 1 |
24952391 | methods | A total of @ diabetic patients with lesions at moderate risk of restenosis ( exclusion criteria : diameter < @ mm or length > @ mm in vessels < @mm , chronic occlusion ) were randomized to a titanium group ( @ patients ) or an everolimus group ( @ patients ) . | 2 |
24952391 | results | Baseline characteristics were well balanced ; @ % of patients were insulin dependent . | 3 |
24952391 | results | At @ year , the incidence of major adverse cardiac events ( death , nonfatal myocardial infarction , stroke , or repeat target vessel revascularization ) was significantly higher in the titanium group than in the everolimus group ( total , @ % vs @ % ; P = @ ; noninsulin-dependent subgroup , @ % vs @ % ; P = @ ; insulin-dependent subgroup , @ % vs @ % ; P = @ ) . | 4 |
24952391 | results | The incidence of death , nonfatal myocardial infarction , stroke , or any revascularization was @ % in the titanium group and @ % in the everolimus group ( P = @ ) . | 5 |
24952391 | results | Target lesion and vessel revascularizations occurred in @ % compared with @ % ( P = @ ) and in @ % compared with @ % ( P = @ ) in the titanium and everolimus groups , respectively . | 6 |
24952391 | results | Angiographic follow-up at @ months showed significantly less late lumen loss in the everolimus group ( in-segment , @ -LSB- standard deviation , @ ) mm vs -@ -LSB- @ -RSB- mm ; in-stent , @ -LSB- @ -RSB- mm vs @ -LSB- @ -RSB- mm ; P < @ ) . | 7 |
24952391 | conclusions | The everolimus-eluting stent is superior to the titanium stent for clinical and angiographic end points in diabetic patients with lesions at moderate risk of restenosis . | 8 |
25516006 | objective | To evaluate the safety of the fixed combination of ibuprofen and famotidine compared with ibuprofen alone from two @-week , multicenter , double-blind trials designed to evaluate the comparative incidence of endoscopically documented upper gastrointestinal ulcers and a @-week double-blind extension study . | 0 |
25516006 | methods | Safety was analyzed by pooling data from the two double-blind trials and the follow-on study . | 1 |
25516006 | methods | Safety was assessed by monitoring the incidence , causality , and severity of adverse events ( AEs ) . | 2 |
25516006 | results | In the pivotal efficacy and safety trials , discontinuation rates due to any cause and dyspepsia were significantly lower for the ibuprofen/famotidine combination versus ibuprofen alone . | 3 |
25516006 | results | Other than dyspepsia , gastrointestinal and cardiovascular AEs of special interest were similar . | 4 |
25516006 | results | Events judged to be treatment related were significantly lower with the ibuprofen/famotidine combination ( @ % vs. @ % ) . | 5 |
25516006 | results | In the safety extension population , there were no differences in the discontinuation rates and the reporting of AEs or serious AEs ( SAEs ) between the two groups . | 6 |
25516006 | results | Gastrointestinal-related events were similar between the groups . | 7 |
25516006 | results | Incidence of cardiovascular-related AEs of special interest were @ % ( ibuprofen/famotidine ) and @ % ( ibuprofen ) ( p = @ ) , possibly due to a higher number of rheumatoid arthritis patients in the combination group . | 8 |
25516006 | results | Of these , @ % were reports of hypertension ( @ % ibuprofen/famotidine vs. @ % ibuprofen ) . | 9 |
25516006 | results | Three cases of hypertension in the ibuprofen/famotidine group were considered treatment related . | 10 |
25516006 | results | The probability of a cardiovascular event decreased during days @-@ of treatment and remained low with continued treatment . | 11 |
25516006 | conclusions | One-year safety data from two pivotal trials and a long-term extension study indicate that the ibuprofen/famotidine combination demonstrates a favorable gastrointestinal safety profile and more patients continued on therapy compared to ibuprofen alone . | 12 |
25516006 | conclusions | No new safety signals have been identified . | 13 |
25516006 | conclusions | These data offer additional evidence supporting a new therapeutic option to improve gastrointestinal safety and adherence for patients who require long-term ibuprofen . | 14 |
24851689 | objective | To compare the effects of volume-controlled ventilation ( VCV ) and pressure-controlled volume-guaranteed ( PCV-VG ) mode during one-lung ventilation ( OLV ) on circulation , pulmonary function and lung injury . | 0 |
24851689 | methods | @ February to @ March in Ningbo No@ . | 1 |
24851689 | methods | Hospital cardiothoracic surgery , @ patients aged @ to @ years ( ASA grade II-III ) undergoing elective thoracoscopic lobectomy were randomly divided into VCV group and PCV-VG group , with @ cases in each group . | 2 |
24851689 | methods | After anesthesia induction and endotracheal intubation , endobronchial blocker was inserted to start OLV . | 3 |
24851689 | methods | Heart rate ( HR ) , mean arterial pressure ( MAP ) , measured tidal volume ( TV ) , peak airway pressure ( Ppeak ) , airway resistance ( Raw ) , chest compliance ( Cdyn ) and the end-tidal carbon dioxide pressure ( PetCO ( @ ) ) were recorded at the time point of @ minutes after turning to the lateral position , @ minutes and @ minutes after OLV , and @ minutes after the resumption of two lung ventilation . | 4 |
24851689 | methods | In the meanwhile , arterial blood gas analysis was conducted to measure indicators of pH , oxygen tension ( PaO ( @ ) ) and carbon dioxide partial pressure ( PaCO ( @ ) ) . | 5 |
24851689 | methods | Blood was drawn before induction , @ hour after OLV and @ hour after the end of surgery , and the concentration of interleukin-@ ( IL-@ ) and tumor necrosis factor-alpha ( TNF - ) were detected by enzyme-linked immunosorbent assay ( ELISA ) . | 6 |
24851689 | results | HR , MAP , TV , PetCO ( @ ) , pH and PaCO ( @ ) in two groups at the time point of @ minutes after turning to the lateral position , @ minutes and @ minutes after OLV , and @ minutes after the resumption of two lung ventilation showed no significant difference ( P > @ ) . | 7 |
24851689 | results | At the point of @ minutes after turning to the lateral position and @ minutes after two lung ventilation , Ppeak and Cdyn of two groups were significantly different ( P < @ ) ( Ppeak :@ @ cmH ( @ ) O , @ @ cmH ( @ ) O for VCV group and @ @ cmH ( @ ) O , @ @ cmH ( @ ) O for PCV-VG group ; Cdyn : @ @ ml/cmH ( @ ) O , @ @ ml/cmH@O for VCV group and @ @ ml/cmH ( @ ) O , @ @ ml/cmH ( @ ) O for PCV-VG group ) . | 8 |
24851689 | results | Compared with VCV group , PCV-VG group showed a lower Ppeak @ minutes and @ minutes after OLV -LSB- ( @ @ cmH ( @ ) O ) vs ( @ @ cmH ( @ ) O ) and ( @ @ cmH ( @ ) O ) vs ( @ @ cmH ( @ ) O ) with a higher Cdyn at the same point ( @ @ ml/cmH ( @ ) O ) vs ( @ @ ml/cmH ( @ ) O ) and @ @ ml/cmH ( @ ) O ) vs ( @ @ ml/cmH ( @ ) O ) -RSB- ( P < @ ) . | 9 |
24851689 | results | Compared with VCV group,IL-@ and TNF - of PCV-VG group @ hour after OLV and @ hour after the end of surgery were significantly lower ( P < @ ) ( IL-@ : @ @ vs @ @ pg/ml and @ @ vs @ @ pg/ml ; TNF - : @ @ vs @ @ pg/ml and @ @ vs. @ @ pg/ml ) . | 10 |
24851689 | conclusions | During one-lung ventilation in thoracoscopic lobectomy , PCV-VG mode has a competitive advantage over VCV mode in terms of pulmonary function and lung protection . | 11 |
24748400 | objective | We compared the recovery profile of propofol and sevoflurane when used for maintenance of anesthesia in elective day care operative procedures . | 0 |
24748400 | methods | One hundred ASA physical status I and II patients , aged between @ and @ years , were randomly assigned to receive either propofol-nitrous oxide or sevoflurane-nitrous oxide maintenance of anesthesia . | 1 |
24748400 | methods | Early and intermediate recovery in terms of cognitive and ambulatory functions was recorded . | 2 |
24748400 | methods | Psychomotor testing , in the form of Trieger dot test and digit symbol substitution test , were performed before surgery and in the post-anesthesia care unit at @ min , @ min , @ h , @ h , and @ h following nitrous oxide switch-off to evaluate intermediate recovery . | 3 |
24748400 | results | There were no significant differences in recovery of early cognitive functions between the two groups , except that patients in the sevoflurane group were more responsive at around @ min following nitrous oxide switch-off and `` recalled address '' earlier than patients in the propofol group . | 4 |
24748400 | results | There was no significant difference in between the two groups with regard to `` home-readiness . '' | 5 |
24748400 | conclusions | Recovery from sevoflurane anesthesia , especially with regard to cognitive functions , may be slightly faster than from propofol , but the difference is not sufficiently significant to affect the time to `` home-readiness '' in patients undergoing day care surgery . | 6 |
24594499 | background | Vertigo imposes considerable health restrictions with significant impact on the patient 's quality of life . | 0 |
24594499 | background | The most effective antivertigo agent is undetermined thus far . | 1 |
24594499 | objective | This study was performed to assess whether promethazine has superior vertigo reduction compared with lorazepam in ED patients . | 2 |