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NIFD_1_S_0097_MR_T1_mprage_S3_DIS3D_br_raw_20120819171037400_152_S161488_I324741_dupl_4 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the right) and supplementary motor cortex (mild atrophy on the right)
- parietal lobe appears structurally intact with no atrophic changes
- temporal lobe atrophy (moderate on the left, severe on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and severe atrophy on the right), planum polare (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy both left/right), inf. temporal gyrus (mild atrophy on the left and severe atrophy on the right), middle temporal gyrus (mild atrophy on the left and severe atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), temporal pole (severe atrophy both left/right) and transverse temporal gyrus (normal-to-mild atrophy on the right)
- limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and severe atrophy on the right), parahippocampal gyrus (mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the right)
- insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: posterior insula (mild atrophy on the left and moderate atrophy on the right), anterior insula (mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left)
- no signs of atrophy detected in the occipital lobe
For the subcortical structures:
- moderate bilateral hippocampus atrophy
- putamen atrophy (normal on the left, mild on the right)
- caudate atrophy (normal-to-mild on the left, mild on the right)
- basal forebrain appears structurally intact with no atrophic changes
- severe bilateral amygdala atrophy
- ventral dc appears structurally intact with no atrophic changes
- thalamus presents with a healthy appearance, free from atrophy
- accumbens atrophy (mild on the left, severe on the right)
- pallidum atrophy (normal on the left, normal-to-mild on the right)
For the ventricles:
- normal-to-mild enlargement of the 3rd ventricle
- lateral ventricle is free from enlargement or excessive growth
- severe bilateral inf. lateral ventricle enlargement
- 4th ventricle maintains its normal volume without signs of enlargement
- normal-to-mild enlargement of the external csf | SV |
NIFD_3_S_0008_MR_T1_mprage_ND_br_raw_20160518225653834_34_S442955_I709965_dupl_5 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the parietal lobe
- no signs of atrophy detected in the temporal lobe
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right)
- limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left)
- occipital lobe remains normal, with no signs of tissue loss
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right) and frontal operculum (moderate atrophy on the left and mild atrophy on the right)
For the subcortical structures:
- ventral dc atrophy (moderate on the left, normal-to-mild on the right)
- basal forebrain remains normal, with no signs of tissue loss
- normal-to-mild bilateral accumbens atrophy
- amygdala appears structurally intact with no atrophic changes
- putamen atrophy (normal-to-mild on the left, normal on the right)
- pallidum atrophy (moderate on the left, normal-to-mild on the right)
- hippocampus appears structurally intact with no atrophic changes
- thalamus atrophy (mild on the left, normal on the right)
- caudate atrophy (mild on the left, normal-to-mild on the right)
For the ventricles:
- external csf appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle is free from enlargement or excessive growth
- mild enlargement of the 3rd ventricle
- lateral ventricle enlargement (mild on the left, normal on the right)
- moderate enlargement of the 4th ventricle | PNFA |
ADNI_037_S_5162_MR_MPRAGE_br_raw_20130503091904515_4_S188623_I369977_dupl_5 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left), middle cingulate gyrus (mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the right)
- frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy both left/right), gyrus rectus (mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left) and middle frontal gyrus (normal-to-mild atrophy on the right)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), central operculum (mild atrophy both left/right), parietal operculum (normal-to-mild atrophy both left/right) and posterior insula (mild atrophy on the right)
- no degenerative or atrophic changes noted in the parietal lobe
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), planum polare (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the left) and fusiform gyrus (normal-to-mild atrophy on the right)
- occipital lobe maintains its normal morphology without atrophic features
For the ventricles:
- normal-to-mild enlargement of the 3rd ventricle
- 4th ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- no enlargement observed in the external csf
- no observable enlargement or abnormal growth in the lateral ventricle
For the subcortical structures:
- normal-to-mild bilateral pallidum atrophy
- thalamus maintains its normal morphology without atrophic features
- ventral dc appears structurally intact with no atrophic changes
- putamen atrophy (mild on the left, normal-to-mild on the right)
- amygdala atrophy (normal on the left, mild on the right)
- no observable atrophic alterations in the accumbens
- caudate atrophy (normal on the left, mild on the right)
- hippocampus atrophy (normal on the left, normal-to-mild on the right)
- basal forebrain appears structurally intact with no atrophic changes | AD |
ADNI_003_S_4142_MR_Accelerated_SAG_IR-SPGR__br_raw_20110906152028494_176_S121316_I254890_dupl_5 | On a T1-weighted brain MRI we observed:
For the ventricles:
- 4th ventricle maintains its normal volume without signs of enlargement
- no enlargement observed in the inf. lateral ventricle
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no pathological changes consistent with enlargement noted in the external csf
For the subcortical structures:
- moderate bilateral caudate atrophy
- moderate bilateral putamen atrophy
- accumbens atrophy (normal-to-mild on the left, normal on the right)
- moderate bilateral thalamus atrophy
- no signs of atrophy detected in the amygdala
- mild bilateral hippocampus atrophy
- severe bilateral ventral dc atrophy
- basal forebrain atrophy (moderate on the left, normal-to-mild on the right)
- mild bilateral pallidum atrophy
For the cerebral cortex:
- severe bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left and severe atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (severe atrophy both left/right), precentral gyrus medial segment (mild atrophy both left/right), subcallosal area (mild atrophy both left/right), sup. frontal gyrus (moderate atrophy both left/right), supplementary motor cortex (moderate atrophy on the left and severe atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and lateral orbital gyrus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy on the left), lingual gyrus (normal-to-mild atrophy on the left), occipital fusiform gyrus (normal-to-mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the right) and occipital pole (normal-to-mild atrophy on the left)
- mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and severe atrophy on the right), postcentral gyrus (mild atrophy on the left and moderate atrophy on the right), precuneus (mild atrophy on the left and severe atrophy on the right) and sup. parietal lobule (mild atrophy on the left and normal-to-mild atrophy on the right)
- moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy both left/right), planum temporale (mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy both left/right), transverse temporal gyrus (moderate atrophy on the left and mild atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left)
- limbic cortex atrophy (severe on the left, moderate on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy both left/right), middle cingulate gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (severe atrophy both left/right)
- insular cortex atrophy (severe on the left, moderate on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), central operculum (severe atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (normal-to-mild atrophy both left/right) and frontal operculum (mild atrophy on the right) | AD |
ADNI_128_S_4832_MR_MPRAGE_br_raw_20120710092632233_36_S157109_I315671_dupl_1 | On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf appears structurally intact, with no evidence of enlargement
- lateral ventricle is free from enlargement or excessive growth
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- no observable enlargement or abnormal growth in the 3rd ventricle
For the subcortical structures:
- ventral dc remains normal, with no signs of tissue loss
- basal forebrain presents with a healthy appearance, free from atrophy
- hippocampus appears structurally intact with no atrophic changes
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- no evidence of atrophy or degeneration in the thalamus
- no signs of atrophy detected in the caudate
- amygdala appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the pallidum
- no pathological changes consistent with atrophy detected in the putamen
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy both left/right) and transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
- insular cortex remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in lateral orbital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), medial frontal cortex (mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild atrophy on the left and normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the right), occipital pole (moderate atrophy on the right) and middle occipital gyrus (normal-to-mild atrophy on the right)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (mild atrophy on the left) and posterior cingulate gyrus (normal-to-mild atrophy on the right)
- no degenerative or atrophic changes noted in the parietal lobe | CN |
ADNI_135_S_5015_MR_MPRAGE_br_raw_20121113152042237_162_S174375_I346353_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the ventral dc
- pallidum atrophy (normal-to-mild on the left, normal on the right)
- amygdala atrophy (normal-to-mild on the left, normal on the right)
- mild bilateral accumbens atrophy
- normal-to-mild bilateral thalamus atrophy
- normal-to-mild bilateral caudate atrophy
- basal forebrain presents with a healthy appearance, free from atrophy
- normal-to-mild bilateral hippocampus atrophy
- normal-to-mild bilateral putamen atrophy
For the ventricles:
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no signs of enlargement detected in the 4th ventricle
- mild bilateral inf. lateral ventricle enlargement
- external csf appears structurally intact, with no evidence of enlargement
- mild enlargement of the 3rd ventricle
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left), anterior orbital gyrus (mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left) and sup. frontal gyrus (normal-to-mild atrophy on the right)
- parietal lobe presents with a healthy appearance, free from atrophy
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left)
- temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the left)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the left)
- occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (mild atrophy both left/right), sup. occipital gyrus (normal-to-mild atrophy both left/right) and inf. occipital gyrus (normal-to-mild atrophy on the right) | AD |
ADNI_024_S_4280_MR_MPRAGE_br_raw_20111018163207473_117_S125582_I261332_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- amygdala atrophy (mild on the left, severe on the right)
- thalamus atrophy (normal-to-mild on the left, normal on the right)
- no pathological changes consistent with atrophy detected in the caudate
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- no evidence of atrophy or degeneration in the putamen
- no evidence of atrophy or degeneration in the basal forebrain
- moderate bilateral hippocampus atrophy
- pallidum presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the ventral dc
For the ventricles:
- no pathological changes consistent with enlargement noted in the 4th ventricle
- mild enlargement of the external csf
- no pathological changes consistent with enlargement noted in the lateral ventricle
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle is free from enlargement or excessive growth
For the cerebral cortex:
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: planum polare (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal pole (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right)
- occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy on the left) and middle occipital gyrus (normal-to-mild atrophy on the left)
- limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left and mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left)
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the left)
- parietal lobe appears structurally intact with no atrophic changes | AD |
ADNI_136_S_4993_MR_MPRAGE_br_raw_20121025150812723_51_S172271_I342522_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- basal forebrain atrophy (normal-to-mild on the left, normal on the right)
- thalamus presents with a healthy appearance, free from atrophy
- the caudate shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the amygdala
- no observable atrophic alterations in the accumbens
- ventral dc maintains its normal morphology without atrophic features
- pallidum appears structurally intact with no atrophic changes
- hippocampus maintains its normal morphology without atrophic features
- putamen presents with a healthy appearance, free from atrophy
For the cerebral cortex:
- parietal lobe maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the temporal lobe
- no signs of atrophy detected in the occipital lobe
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in central operculum (mild atrophy on the left), parietal operculum (normal-to-mild atrophy on the left) and frontal operculum (normal-to-mild atrophy on the right)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), gyrus rectus (mild atrophy on the left), lateral orbital gyrus (mild atrophy on the left) and medial frontal cortex (normal-to-mild atrophy on the left)
- limbic cortex appears structurally intact with no atrophic changes
For the ventricles:
- normal-to-mild enlargement of the 3rd ventricle
- inf. lateral ventricle enlargement (moderate on the left, normal-to-mild on the right)
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- the external csf shows no structural abnormalities indicative of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected | AD |
ADNI_016_S_5057_MR_Accelerated_SAG_IR-SPGR__br_raw_20130226082518326_195_S183095_I361230_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no observable atrophic alterations in the thalamus
- no evidence of atrophy or degeneration in the pallidum
- putamen presents with a healthy appearance, free from atrophy
- hippocampus remains normal, with no signs of tissue loss
- basal forebrain maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the caudate
- no pathological changes consistent with atrophy detected in the ventral dc
- amygdala atrophy (normal-to-mild on the left, normal on the right)
- no pathological changes consistent with atrophy detected in the accumbens
For the ventricles:
- 4th ventricle maintains its normal volume without signs of enlargement
- lateral ventricle appears structurally intact, with no evidence of enlargement
- moderate bilateral inf. lateral ventricle enlargement
- external csf remains within normal size parameters, with no enlargement detected
- no abnormal enlargement observed in the 3rd ventricle
For the cerebral cortex:
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. temporal gyrus (normal-to-mild atrophy both left/right), planum temporale (mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the right)
- no signs of atrophy detected in the frontal lobe
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the left)
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy both left/right), frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (mild atrophy on the left)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle occipital gyrus (mild atrophy on the right) and occipital fusiform gyrus (normal-to-mild atrophy on the left)
- parietal lobe remains normal, with no signs of tissue loss | AD |
NIFD_1_S_0339_MR_T1_mprage_S3_DIS3D_br_raw_20170629002457144_144_S577807_I867541_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- pallidum atrophy (normal-to-mild on the left, mild on the right)
- putamen atrophy (mild on the left, moderate on the right)
- accumbens atrophy (moderate on the left, severe on the right)
- normal-to-mild bilateral thalamus atrophy
- severe bilateral hippocampus atrophy
- no observable atrophic alterations in the basal forebrain
- severe bilateral amygdala atrophy
- caudate atrophy (normal on the left, mild on the right)
- normal-to-mild bilateral ventral dc atrophy
For the ventricles:
- no enlargement observed in the external csf
- no signs of enlargement detected in the 4th ventricle
- inf. lateral ventricle enlargement (moderate on the left, severe on the right)
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the 3rd ventricle
For the cerebral cortex:
- parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right) and postcentral gyrus medial segment (normal-to-mild atrophy on the left)
- limbic cortex atrophy (mild on the left, moderate on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the left and moderate atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the left)
- temporal lobe atrophy (moderate on the left, severe on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and moderate atrophy on the right), planum polare (mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild atrophy both left/right), temporal pole (severe atrophy both left/right) and middle temporal gyrus (severe atrophy on the right)
- occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), middle occipital gyrus (normal-to-mild atrophy on the right), inf. occipital gyrus (mild atrophy on the left) and cuneus (normal-to-mild atrophy on the right)
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and moderate atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right) and lateral orbital gyrus (normal-to-mild atrophy on the right)
- insular cortex atrophy (mild on the left, moderate on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right), posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), central operculum (mild atrophy both left/right), frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) | SV |
NIFD_1_S_0269_MR_t1_mprage__br_raw_20160902220526927_82_S496410_I772673_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens atrophy (normal-to-mild on the left, mild on the right)
- no signs of atrophy detected in the caudate
- no degenerative or atrophic changes noted in the amygdala
- thalamus remains normal, with no signs of tissue loss
- pallidum appears structurally intact with no atrophic changes
- putamen atrophy (normal-to-mild on the left, normal on the right)
- no degenerative or atrophic changes noted in the basal forebrain
- no degenerative or atrophic changes noted in the hippocampus
- no degenerative or atrophic changes noted in the ventral dc
For the ventricles:
- no pathological changes consistent with enlargement noted in the 4th ventricle
- normal-to-mild enlargement of the external csf
- no observable enlargement or abnormal growth in the lateral ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- no abnormal enlargement observed in the inf. lateral ventricle
For the cerebral cortex:
- no degenerative or atrophic changes noted in the parietal lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the left)
- limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (normal-to-mild atrophy both left/right), occipital fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and inf. occipital gyrus (normal-to-mild atrophy on the right)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left)
- insular cortex appears structurally intact with no atrophic changes | CN |
NIFD_1_S_0175_MR_T1_mprage_S3_DIS3D_br_raw_20140701125948453_146_S223924_I434014_dupl_3 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- frontal lobe presents with a healthy appearance, free from atrophy
- limbic cortex appears structurally intact with no atrophic changes
- the occipital lobe shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the temporal lobe
- insular cortex maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the parietal lobe
For the subcortical structures:
- no degenerative or atrophic changes noted in the amygdala
- putamen presents with a healthy appearance, free from atrophy
- ventral dc appears structurally intact with no atrophic changes
- hippocampus appears structurally intact with no atrophic changes
- no observable atrophic alterations in the thalamus
- no evidence of atrophy or degeneration in the accumbens
- no observable atrophic alterations in the caudate
- no signs of atrophy detected in the pallidum
- basal forebrain presents with a healthy appearance, free from atrophy
For the ventricles:
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- external csf is free from enlargement or excessive growth
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- mild enlargement of the 3rd ventricle
- no observable enlargement or abnormal growth in the 4th ventricle | CN |
ADNI_070_S_4719_MR_MPRAGE_br_raw_20120521142246850_171_S151143_I305573_dupl_1 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no abnormal enlargement observed in the 4th ventricle
- normal-to-mild enlargement of the external csf
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle enlargement (mild on the left, normal on the right)
For the cerebral cortex:
- no signs of atrophy detected in the occipital lobe
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left)
- no observable atrophic alterations in the frontal lobe
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy both left/right), sup. parietal lobule (normal-to-mild atrophy on the left and mild atrophy on the right) and precuneus (mild atrophy on the left)
- normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: posterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (moderate atrophy on the left and mild atrophy on the right), entorhinal area (normal-to-mild atrophy on the left) and anterior cingulate gyrus (normal-to-mild atrophy on the right)
- temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (moderate atrophy on the left)
For the subcortical structures:
- putamen atrophy (normal-to-mild on the left, normal on the right)
- no evidence of atrophy or degeneration in the thalamus
- caudate remains normal, with no signs of tissue loss
- amygdala atrophy (moderate on the left, normal-to-mild on the right)
- no pathological changes consistent with atrophy detected in the accumbens
- pallidum presents with a healthy appearance, free from atrophy
- basal forebrain presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the ventral dc
- hippocampus atrophy (severe on the left, normal-to-mild on the right) | AD |
NIFD_1_S_0237_MR_t1_mprage__br_raw_20160902142657075_120_S495712_I771873_dupl_5 | On a T1-weighted brain MRI we observed:
For the ventricles:
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- 4th ventricle maintains its normal volume without signs of enlargement
- no signs of enlargement detected in the external csf
- 3rd ventricle maintains its normal volume without signs of enlargement
- no observable enlargement or abnormal growth in the lateral ventricle
For the subcortical structures:
- no observable atrophic alterations in the ventral dc
- no evidence of atrophy or degeneration in the hippocampus
- the pallidum shows no structural abnormalities indicative of atrophy
- thalamus maintains its normal morphology without atrophic features
- putamen remains normal, with no signs of tissue loss
- normal-to-mild bilateral caudate atrophy
- no signs of atrophy detected in the basal forebrain
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- amygdala remains normal, with no signs of tissue loss
For the cerebral cortex:
- the occipital lobe shows no structural abnormalities indicative of atrophy
- temporal lobe appears structurally intact with no atrophic changes
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy on the right)
- insular cortex remains normal, with no signs of tissue loss
- frontal lobe maintains its normal morphology without atrophic features
- limbic cortex presents with a healthy appearance, free from atrophy | CN |
ADNI_003_S_5187_MR_Accelerated_SAG_IR-SPGR__br_raw_20130610202342271_157_S191910_I375951_dupl_1 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no signs of atrophy detected in the ventral dc
- amygdala atrophy (moderate on the left, mild on the right)
- no observable atrophic alterations in the basal forebrain
- accumbens appears structurally intact with no atrophic changes
- no observable atrophic alterations in the thalamus
- no evidence of atrophy or degeneration in the pallidum
- hippocampus atrophy (moderate on the left, severe on the right)
- no degenerative or atrophic changes noted in the putamen
- no signs of atrophy detected in the caudate
For the ventricles:
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- no enlargement observed in the 4th ventricle
- lateral ventricle enlargement (normal-to-mild on the left, mild on the right)
- normal-to-mild enlargement of the external csf
- inf. lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
For the cerebral cortex:
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the right), transverse temporal gyrus (normal-to-mild atrophy on the left), inf. temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the left)
- occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy on the left and mild atrophy on the right), occipital fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), occipital pole (normal-to-mild atrophy on the left and mild atrophy on the right) and cuneus (normal-to-mild atrophy on the right)
- limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right) and anterior cingulate gyrus (mild atrophy on the left)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in precentral gyrus medial segment (mild atrophy on the left), sup. frontal gyrus medial segment (mild atrophy on the right), supplementary motor cortex (mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (mild atrophy on the left) and precentral gyrus (normal-to-mild atrophy on the left)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. parietal lobule (normal-to-mild atrophy on the left and mild atrophy on the right), precuneus (mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left) and postcentral gyrus medial segment (normal-to-mild atrophy on the left)
- the insular cortex shows no structural abnormalities indicative of atrophy | AD |
NIFD_2_S_0027_MR_MT1__GradWarp__N3m_Br_20130103113648528_S177998_I353170_dupl_3 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- parietal lobe remains normal, with no signs of tissue loss
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (moderate atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy both left/right)
- the insular cortex shows no structural abnormalities indicative of atrophy
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right) and fusiform gyrus (normal-to-mild atrophy on the left)
- the frontal lobe shows no structural abnormalities indicative of atrophy
- occipital lobe appears structurally intact with no atrophic changes
For the ventricles:
- severe enlargement of the external csf
- 3rd ventricle is free from enlargement or excessive growth
- lateral ventricle remains within normal size parameters, with no enlargement detected
- normal-to-mild enlargement of the 4th ventricle
- inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
For the subcortical structures:
- severe bilateral amygdala atrophy
- no observable atrophic alterations in the thalamus
- putamen remains normal, with no signs of tissue loss
- the pallidum shows no structural abnormalities indicative of atrophy
- caudate remains normal, with no signs of tissue loss
- accumbens atrophy (normal on the left, mild on the right)
- basal forebrain presents with a healthy appearance, free from atrophy
- hippocampus atrophy (severe on the left, moderate on the right)
- no observable atrophic alterations in the ventral dc | BV |
NIFD_1_S_0194_MR_T1_mprage_S3_DIS3D_br_raw_20140831195557073_107_S229201_I441537_dupl_1 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- pallidum atrophy (normal on the left, normal-to-mild on the right)
- no evidence of atrophy or degeneration in the accumbens
- putamen atrophy (mild on the left, moderate on the right)
- no degenerative or atrophic changes noted in the ventral dc
- basal forebrain atrophy (normal on the left, normal-to-mild on the right)
- thalamus presents with a healthy appearance, free from atrophy
- no observable atrophic alterations in the hippocampus
- caudate atrophy (normal on the left, normal-to-mild on the right)
- amygdala appears structurally intact with no atrophic changes
For the cerebral cortex:
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left), sup. temporal gyrus (moderate atrophy on the right) and transverse temporal gyrus (severe atrophy on the right)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (normal-to-mild atrophy both left/right), lingual gyrus (mild atrophy on the right), cuneus (normal-to-mild atrophy on the right), middle occipital gyrus (normal-to-mild atrophy on the left) and sup. occipital gyrus (normal-to-mild atrophy on the left)
- insular cortex atrophy (normal on the left, severe on the right), with focal volume loss observed in the following subregions: parietal operculum (normal-to-mild atrophy on the left and moderate atrophy on the right), anterior insula (severe atrophy on the right), posterior insula (severe atrophy on the right) and central operculum (moderate atrophy on the right)
- parietal lobe atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right), angular gyrus (moderate atrophy on the right), sup. parietal lobule (normal-to-mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the right) and postcentral gyrus medial segment (normal-to-mild atrophy on the left)
- no pathological changes consistent with atrophy detected in the limbic cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (normal-to-mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left)
For the ventricles:
- normal-to-mild enlargement of the external csf
- 3rd ventricle maintains its normal volume without signs of enlargement
- no signs of enlargement detected in the lateral ventricle
- no signs of enlargement detected in the inf. lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle | PNFA |
NIFD_1_S_0072_MR_T1_mprage_S3_DIS3D_br_raw_20170816175300325_153_S597008_I890174_dupl_3 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the occipital lobe
- temporal lobe atrophy (severe on the left, moderate on the right), with focal volume loss observed in the following subregions: fusiform gyrus (severe atrophy on the left and normal-to-mild atrophy on the right), planum temporale (moderate atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (severe atrophy on the left and mild atrophy on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), temporal pole (severe atrophy on the left and moderate atrophy on the right) and planum polare (normal-to-mild atrophy on the left)
- limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (severe atrophy on the left and moderate atrophy on the right) and parahippocampal gyrus (severe atrophy on the left and moderate atrophy on the right)
- parietal lobe remains normal, with no signs of tissue loss
- insular cortex atrophy (moderate on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy on the left) and central operculum (normal-to-mild atrophy on the right)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (mild atrophy on the left), triangular inf. frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus medial segment (normal-to-mild atrophy on the right) and subcallosal area (normal-to-mild atrophy on the left)
For the subcortical structures:
- severe bilateral amygdala atrophy
- caudate atrophy (normal-to-mild on the left, normal on the right)
- accumbens atrophy (severe on the left, mild on the right)
- ventral dc remains normal, with no signs of tissue loss
- putamen atrophy (severe on the left, normal-to-mild on the right)
- pallidum atrophy (mild on the left, normal on the right)
- thalamus atrophy (mild on the left, normal on the right)
- basal forebrain appears structurally intact with no atrophic changes
- hippocampus atrophy (severe on the left, moderate on the right)
For the ventricles:
- inf. lateral ventricle enlargement (severe on the left, mild on the right)
- no abnormal enlargement observed in the 3rd ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle
- mild enlargement of the external csf | SV |
ADNI_019_S_4477_MR_MPRAGE_br_raw_20120126085251352_103_S138533_I280783_dupl_3 | On a T1-weighted brain MRI we observed:
For the ventricles:
- lateral ventricle maintains its normal volume without signs of enlargement
- no observable enlargement or abnormal growth in the 4th ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- the external csf shows no structural abnormalities indicative of enlargement
For the subcortical structures:
- normal-to-mild bilateral ventral dc atrophy
- normal-to-mild bilateral putamen atrophy
- moderate bilateral accumbens atrophy
- caudate atrophy (moderate on the left, mild on the right)
- normal-to-mild bilateral basal forebrain atrophy
- amygdala atrophy (moderate on the left, mild on the right)
- pallidum atrophy (mild on the left, normal-to-mild on the right)
- normal-to-mild bilateral thalamus atrophy
- severe bilateral hippocampus atrophy
For the cerebral cortex:
- moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus medial segment (normal-to-mild atrophy both left/right), precuneus (mild atrophy both left/right), sup. parietal lobule (mild atrophy on the left and normal-to-mild atrophy on the right) and supramarginal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left/right), medial frontal cortex (mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), sup. frontal gyrus (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), supplementary motor cortex (normal-to-mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (mild atrophy on the right) and lateral orbital gyrus (mild atrophy on the left)
- mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: posterior insula (moderate atrophy on the left and mild atrophy on the right), central operculum (normal-to-mild atrophy on the left and mild atrophy on the right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right)
- moderate bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), middle cingulate gyrus (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and moderate atrophy on the right)
- mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy on the left and mild atrophy on the right), lingual gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), sup. occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), occipital pole (mild atrophy on the left and normal-to-mild atrophy on the right), middle occipital gyrus (normal-to-mild atrophy on the right) and cuneus (normal-to-mild atrophy on the left)
- moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum polare (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (moderate atrophy both left/right), sup. temporal gyrus (mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) | AD |
ADNI_018_S_5240_MR_MPRAGE_br_raw_20130723160412209_118_S196225_I382181_dupl_3 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (mild atrophy on the right)
- normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right), parietal operculum (normal-to-mild atrophy both left/right), posterior insula (normal-to-mild atrophy on the left) and anterior insula (normal-to-mild atrophy on the right)
- parietal lobe maintains its normal morphology without atrophic features
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (mild atrophy on the right)
- limbic cortex appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the frontal lobe
For the subcortical structures:
- caudate maintains its normal morphology without atrophic features
- no signs of atrophy detected in the ventral dc
- thalamus atrophy (normal on the left, normal-to-mild on the right)
- no signs of atrophy detected in the basal forebrain
- hippocampus remains normal, with no signs of tissue loss
- accumbens remains normal, with no signs of tissue loss
- normal-to-mild bilateral amygdala atrophy
- no degenerative or atrophic changes noted in the putamen
- pallidum remains normal, with no signs of tissue loss
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- normal-to-mild enlargement of the 3rd ventricle
- lateral ventricle maintains its normal volume without signs of enlargement
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no observable enlargement or abnormal growth in the external csf | AD |
NIFD_1_S_0273_MR_t1_mprage_short__br_raw_20160903183136298_99_S496584_I772871_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- normal-to-mild bilateral ventral dc atrophy
- amygdala atrophy (normal on the left, mild on the right)
- accumbens atrophy (normal-to-mild on the left, normal on the right)
- normal-to-mild bilateral thalamus atrophy
- caudate remains normal, with no signs of tissue loss
- hippocampus atrophy (normal-to-mild on the left, mild on the right)
- pallidum atrophy (mild on the left, normal-to-mild on the right)
- basal forebrain appears structurally intact with no atrophic changes
- mild bilateral putamen atrophy
For the ventricles:
- no observable enlargement or abnormal growth in the external csf
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- 4th ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the right), parahippocampal gyrus (mild atrophy on the right) and entorhinal area (normal-to-mild atrophy on the right)
- no evidence of atrophy or degeneration in the insular cortex
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in posterior orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (mild atrophy on the left), opercular inf. frontal gyrus (mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left), anterior orbital gyrus (mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the right) and middle frontal gyrus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), planum polare (moderate atrophy on the left), middle temporal gyrus (mild atrophy on the left) and fusiform gyrus (normal-to-mild atrophy on the right)
- mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy both left/right), postcentral gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), precuneus (mild atrophy both left/right), supramarginal gyrus (normal-to-mild atrophy both left/right) and sup. parietal lobule (normal-to-mild atrophy on the right)
- occipital lobe atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: lingual gyrus (mild atrophy both left/right), middle occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the left), inf. occipital gyrus (normal-to-mild atrophy on the left) and calcarine cortex (normal-to-mild atrophy on the left) | CN |
NIFD_1_S_0238_MR_t1_mprage__br_raw_20160902144226204_127_S495765_I771932_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- basal forebrain maintains its normal morphology without atrophic features
- no observable atrophic alterations in the accumbens
- no evidence of atrophy or degeneration in the amygdala
- normal-to-mild bilateral hippocampus atrophy
- no pathological changes consistent with atrophy detected in the thalamus
- no pathological changes consistent with atrophy detected in the pallidum
- the caudate shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the ventral dc
- putamen appears structurally intact with no atrophic changes
For the cerebral cortex:
- no signs of atrophy detected in the occipital lobe
- parietal lobe appears structurally intact with no atrophic changes
- no signs of atrophy detected in the limbic cortex
- insular cortex maintains its normal morphology without atrophic features
- the frontal lobe shows no structural abnormalities indicative of atrophy
- temporal lobe maintains its normal morphology without atrophic features
For the ventricles:
- 3rd ventricle maintains its normal volume without signs of enlargement
- 4th ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
- normal-to-mild enlargement of the external csf | CN |
NIFD_1_S_0209_MR_T1_mprage_S3_DIS3D_br_raw_20140901123615201_24_S229648_I442043_dupl_5 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the insular cortex shows no structural abnormalities indicative of atrophy
- normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the right) and entorhinal area (normal-to-mild atrophy on the right)
- frontal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), frontal pole (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the right) and gyrus rectus (normal-to-mild atrophy on the left)
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right)
- no degenerative or atrophic changes noted in the parietal lobe
- no signs of atrophy detected in the occipital lobe
For the subcortical structures:
- hippocampus remains normal, with no signs of tissue loss
- mild bilateral accumbens atrophy
- normal-to-mild bilateral thalamus atrophy
- no pathological changes consistent with atrophy detected in the ventral dc
- putamen atrophy (normal-to-mild on the left, moderate on the right)
- no signs of atrophy detected in the basal forebrain
- severe bilateral caudate atrophy
- pallidum atrophy (normal on the left, normal-to-mild on the right)
- normal-to-mild bilateral amygdala atrophy
For the ventricles:
- inf. lateral ventricle enlargement (normal-to-mild on the left, mild on the right)
- 4th ventricle is free from enlargement or excessive growth
- mild bilateral lateral ventricle enlargement
- mild enlargement of the external csf
- moderate enlargement of the 3rd ventricle | BV |
ADNI_024_S_4280_MR_MPRAGE_br_raw_20111018163207473_117_S125582_I261332_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no degenerative or atrophic changes noted in the caudate
- no pathological changes consistent with atrophy detected in the basal forebrain
- the ventral dc shows no structural abnormalities indicative of atrophy
- thalamus atrophy (normal-to-mild on the left, normal on the right)
- moderate bilateral hippocampus atrophy
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- no degenerative or atrophic changes noted in the pallidum
- putamen remains normal, with no signs of tissue loss
- amygdala atrophy (mild on the left, severe on the right)
For the ventricles:
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- mild enlargement of the external csf
- no enlargement observed in the 3rd ventricle
- no observable enlargement or abnormal growth in the lateral ventricle
- no observable enlargement or abnormal growth in the 4th ventricle
For the cerebral cortex:
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (normal-to-mild atrophy on the left)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in frontal pole (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right) and supplementary motor cortex (normal-to-mild atrophy on the right)
- the parietal lobe shows no structural abnormalities indicative of atrophy
- occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy on the left) and middle occipital gyrus (normal-to-mild atrophy on the left)
- limbic cortex atrophy (mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy on the left and mild atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior cingulate gyrus (mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left)
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: planum polare (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left) | AD |
ADNI_127_S_4198_MR_Accelerated_Sag_IR-SPGR__br_raw_20110902083648052_131_S121087_I254317_dupl_3 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- no observable enlargement or abnormal growth in the external csf
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- no pathological changes consistent with enlargement noted in the 3rd ventricle
For the cerebral cortex:
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in calcarine cortex (normal-to-mild atrophy on the left and mild atrophy on the right), cuneus (normal-to-mild atrophy both left/right), occipital pole (normal-to-mild atrophy both left/right) and inf. occipital gyrus (mild atrophy on the left)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the right) and precentral gyrus (normal-to-mild atrophy on the left)
- insular cortex presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the limbic cortex
- temporal lobe remains normal, with no signs of tissue loss
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (normal-to-mild atrophy both left/right), supramarginal gyrus (mild atrophy on the right), precuneus (normal-to-mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the left)
For the subcortical structures:
- normal-to-mild bilateral accumbens atrophy
- amygdala atrophy (normal-to-mild on the left, normal on the right)
- no observable atrophic alterations in the ventral dc
- basal forebrain appears structurally intact with no atrophic changes
- thalamus atrophy (normal-to-mild on the left, normal on the right)
- pallidum remains normal, with no signs of tissue loss
- no observable atrophic alterations in the caudate
- putamen maintains its normal morphology without atrophic features
- hippocampus maintains its normal morphology without atrophic features | CN |
ADNI_098_S_4003_MR_Accelerated_Sag_IR-SPGR__br_raw_20110322131336182_62_S102158_I224611_dupl_2 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- caudate maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the pallidum
- accumbens maintains its normal morphology without atrophic features
- ventral dc presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the thalamus
- no observable atrophic alterations in the putamen
- amygdala appears structurally intact with no atrophic changes
- the basal forebrain shows no structural abnormalities indicative of atrophy
- no observable atrophic alterations in the hippocampus
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no signs of enlargement detected in the 4th ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the external csf
- no enlargement observed in the 3rd ventricle
For the cerebral cortex:
- insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy on the right), parietal operculum (mild atrophy on the right) and posterior insula (normal-to-mild atrophy on the right)
- limbic cortex maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the occipital lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum polare (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right)
- parietal lobe presents with a healthy appearance, free from atrophy
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in triangular inf. frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left) | CN |
ADNI_127_S_5028_MR_Accelerated_Sag_IR-SPGR__br_raw_20121114162609124_113_S174622_I346691_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- normal-to-mild bilateral amygdala atrophy
- no evidence of atrophy or degeneration in the pallidum
- basal forebrain atrophy (normal on the left, normal-to-mild on the right)
- no observable atrophic alterations in the thalamus
- no degenerative or atrophic changes noted in the putamen
- ventral dc appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the accumbens
- normal-to-mild bilateral caudate atrophy
- hippocampus atrophy (normal on the left, normal-to-mild on the right)
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no enlargement observed in the 4th ventricle
- external csf remains within normal size parameters, with no enlargement detected
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no observable enlargement or abnormal growth in the 3rd ventricle
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in middle frontal gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right) and supplementary motor cortex (mild atrophy on the right)
- occipital lobe appears structurally intact with no atrophic changes
- no observable atrophic alterations in the temporal lobe
- limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the right)
- insular cortex appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the parietal lobe | AD |
ADNI_098_S_4201_MR_Accelerated_Sag_IR-SPGR__br_raw_20110915152919253_90_S122171_I256181_dupl_4 | On a T1-weighted brain MRI we observed:
For the ventricles:
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- normal-to-mild enlargement of the external csf
- no pathological changes consistent with enlargement noted in the 4th ventricle
- no observable enlargement or abnormal growth in the lateral ventricle
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the right)
- limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: parahippocampal gyrus (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy on the right)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (normal-to-mild atrophy on the right) and middle occipital gyrus (mild atrophy on the right)
- parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the right)
- temporal lobe atrophy (normal-to-mild on the left, moderate on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left and severe atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the right)
- no observable atrophic alterations in the insular cortex
For the subcortical structures:
- amygdala atrophy (normal-to-mild on the left, moderate on the right)
- no signs of atrophy detected in the ventral dc
- accumbens atrophy (normal-to-mild on the left, mild on the right)
- normal-to-mild bilateral caudate atrophy
- hippocampus atrophy (normal on the left, normal-to-mild on the right)
- putamen atrophy (normal on the left, normal-to-mild on the right)
- thalamus presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the pallidum
- basal forebrain appears structurally intact with no atrophic changes | AD |
NIFD_1_S_0266_MR_t1_mprage__br_raw_20160902212027546_148_S496336_I772588_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no observable atrophic alterations in the basal forebrain
- pallidum appears structurally intact with no atrophic changes
- no pathological changes consistent with atrophy detected in the thalamus
- no observable atrophic alterations in the ventral dc
- hippocampus atrophy (normal on the left, normal-to-mild on the right)
- amygdala remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the accumbens
- putamen presents with a healthy appearance, free from atrophy
- caudate presents with a healthy appearance, free from atrophy
For the cerebral cortex:
- insular cortex appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the limbic cortex
- no observable atrophic alterations in the occipital lobe
- no evidence of atrophy or degeneration in the parietal lobe
- temporal lobe maintains its normal morphology without atrophic features
- frontal lobe presents with a healthy appearance, free from atrophy
For the ventricles:
- no signs of enlargement detected in the 4th ventricle
- external csf appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the 3rd ventricle
- lateral ventricle enlargement (mild on the left, moderate on the right)
- no enlargement observed in the inf. lateral ventricle | CN |
ADNI_153_S_4172_MR_MPRAGE_br_raw_20110817113413375_135_S119196_I251187_dupl_1 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: parietal operculum (mild atrophy on the right)
- occipital lobe presents with a healthy appearance, free from atrophy
- no pathological changes consistent with atrophy detected in the limbic cortex
- no pathological changes consistent with atrophy detected in the parietal lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in planum temporale (mild atrophy on the right) and inf. temporal gyrus (normal-to-mild atrophy on the left)
- no evidence of atrophy or degeneration in the frontal lobe
For the ventricles:
- normal-to-mild enlargement of the external csf
- no observable enlargement or abnormal growth in the 3rd ventricle
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- 4th ventricle remains within normal size parameters, with no enlargement detected
For the subcortical structures:
- no pathological changes consistent with atrophy detected in the thalamus
- basal forebrain appears structurally intact with no atrophic changes
- amygdala atrophy (normal-to-mild on the left, normal on the right)
- putamen atrophy (moderate on the left, normal-to-mild on the right)
- caudate atrophy (moderate on the left, normal-to-mild on the right)
- accumbens atrophy (mild on the left, normal-to-mild on the right)
- the pallidum shows no structural abnormalities indicative of atrophy
- ventral dc remains normal, with no signs of tissue loss
- hippocampus atrophy (normal-to-mild on the left, normal on the right) | AD |
ADNI_021_S_4718_MR_Accelerated_Sag_IR-SPGR__br_raw_20120516162344538_10_S150673_I304759_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- caudate atrophy (normal-to-mild on the left, mild on the right)
- moderate bilateral amygdala atrophy
- basal forebrain remains normal, with no signs of tissue loss
- mild bilateral accumbens atrophy
- no signs of atrophy detected in the pallidum
- hippocampus atrophy (normal-to-mild on the left, mild on the right)
- normal-to-mild bilateral putamen atrophy
- thalamus atrophy (normal-to-mild on the left, mild on the right)
- ventral dc maintains its normal morphology without atrophic features
For the ventricles:
- inf. lateral ventricle enlargement (mild on the left, severe on the right)
- 4th ventricle is free from enlargement or excessive growth
- normal-to-mild enlargement of the external csf
- normal-to-mild enlargement of the 3rd ventricle
- lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
For the cerebral cortex:
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right)
- parietal lobe atrophy (normal-to-mild on the left, moderate on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and severe atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precuneus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy both left/right) and supramarginal gyrus (normal-to-mild atrophy both left/right)
- frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the right), posterior orbital gyrus (mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the left)
- the occipital lobe shows no structural abnormalities indicative of atrophy
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy both left/right), anterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy on the right) and parietal operculum (normal-to-mild atrophy on the left)
- mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the right) | AD |
ADNI_016_S_5032_MR_Accelerated_SAG_IR-SPGR__br_raw_20121130134021740_63_S175940_I348593_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- ventral dc presents with a healthy appearance, free from atrophy
- thalamus atrophy (normal-to-mild on the left, mild on the right)
- hippocampus atrophy (normal-to-mild on the left, mild on the right)
- basal forebrain atrophy (normal-to-mild on the left, normal on the right)
- normal-to-mild bilateral putamen atrophy
- mild bilateral accumbens atrophy
- pallidum atrophy (normal on the left, normal-to-mild on the right)
- amygdala atrophy (mild on the left, moderate on the right)
- caudate atrophy (normal on the left, normal-to-mild on the right)
For the cerebral cortex:
- insular cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left), central operculum (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the left)
- frontal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the left), medial frontal cortex (moderate atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left), supplementary motor cortex (mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left), posterior orbital gyrus (normal-to-mild atrophy on the right) and subcallosal area (normal-to-mild atrophy on the right)
- limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the right)
- occipital lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy on the left and mild atrophy on the right), cuneus (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy both left/right), occipital pole (normal-to-mild atrophy both left/right), lingual gyrus (normal-to-mild atrophy on the left) and occipital fusiform gyrus (mild atrophy on the right)
- no degenerative or atrophic changes noted in the parietal lobe
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum polare (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy both left/right), inf. temporal gyrus (mild atrophy on the left), sup. temporal gyrus (normal-to-mild atrophy on the left) and transverse temporal gyrus (normal-to-mild atrophy on the right)
For the ventricles:
- 3rd ventricle is free from enlargement or excessive growth
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no pathological changes consistent with enlargement noted in the lateral ventricle
- external csf remains within normal size parameters, with no enlargement detected
- no observable enlargement or abnormal growth in the 4th ventricle | AD |
ADNI_036_S_4894_MR_MPRAGE_br_raw_20120810124944746_175_S160488_I323094_dupl_5 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left), anterior cingulate gyrus (normal-to-mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the left) and parahippocampal gyrus (normal-to-mild atrophy on the left)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in opercular inf. frontal gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left) and middle frontal gyrus (normal-to-mild atrophy on the left)
- temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: inf. temporal gyrus (normal-to-mild atrophy both left/right), middle temporal gyrus (normal-to-mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left) and temporal pole (normal-to-mild atrophy on the left)
- parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right), postcentral gyrus medial segment (normal-to-mild atrophy on the left) and supramarginal gyrus (mild atrophy on the left)
- insular cortex maintains its normal morphology without atrophic features
- occipital lobe remains normal, with no signs of tissue loss
For the ventricles:
- inf. lateral ventricle enlargement (moderate on the left, normal on the right)
- 4th ventricle is free from enlargement or excessive growth
- lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
- normal-to-mild enlargement of the 3rd ventricle
- mild enlargement of the external csf
For the subcortical structures:
- the pallidum shows no structural abnormalities indicative of atrophy
- mild bilateral caudate atrophy
- no observable atrophic alterations in the ventral dc
- normal-to-mild bilateral putamen atrophy
- thalamus presents with a healthy appearance, free from atrophy
- hippocampus atrophy (moderate on the left, mild on the right)
- amygdala atrophy (moderate on the left, normal on the right)
- accumbens atrophy (normal-to-mild on the left, normal on the right)
- basal forebrain remains normal, with no signs of tissue loss | AD |
ADNI_098_S_4201_MR_Accelerated_Sag_IR-SPGR__br_raw_20110915152919253_90_S122171_I256181_dupl_3 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no signs of enlargement detected in the 3rd ventricle
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- no pathological changes consistent with enlargement noted in the 4th ventricle
- normal-to-mild enlargement of the external csf
- lateral ventricle is free from enlargement or excessive growth
For the subcortical structures:
- ventral dc remains normal, with no signs of tissue loss
- putamen atrophy (normal on the left, normal-to-mild on the right)
- no signs of atrophy detected in the thalamus
- no pathological changes consistent with atrophy detected in the pallidum
- amygdala atrophy (normal-to-mild on the left, moderate on the right)
- accumbens atrophy (normal-to-mild on the left, mild on the right)
- hippocampus atrophy (normal on the left, normal-to-mild on the right)
- normal-to-mild bilateral caudate atrophy
- the basal forebrain shows no structural abnormalities indicative of atrophy
For the cerebral cortex:
- limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: parahippocampal gyrus (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal-to-mild atrophy on the right)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (normal-to-mild atrophy on the right) and middle occipital gyrus (mild atrophy on the right)
- temporal lobe atrophy (normal-to-mild on the left, moderate on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left and severe atrophy on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the right)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (mild atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy both left/right), gyrus rectus (mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the right)
- parietal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. parietal lobule (normal-to-mild atrophy on the right)
- insular cortex maintains its normal morphology without atrophic features | AD |
NIFD_1_S_0091_MR_T1_mprage_S3_DIS3D_br_raw_20170817104021048_43_S597455_I890811_dupl_5 | On a T1-weighted brain MRI we observed:
For the ventricles:
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the external csf
- lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
- 3rd ventricle maintains its normal volume without signs of enlargement
For the cerebral cortex:
- temporal lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), planum polare (mild atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy both left/right), sup. temporal gyrus (mild atrophy both left/right), transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the right)
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), posterior orbital gyrus (mild atrophy both left/right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus medial segment (mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and middle frontal gyrus (normal-to-mild atrophy on the right)
- insular cortex atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy both left/right), posterior insula (moderate atrophy both left/right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (moderate atrophy on the left and mild atrophy on the right)
- mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right), anterior cingulate gyrus (normal-to-mild atrophy both left/right), posterior cingulate gyrus (mild atrophy both left/right) and parahippocampal gyrus (mild atrophy on the left)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (normal-to-mild atrophy on the right), inf. occipital gyrus (mild atrophy on the right) and occipital fusiform gyrus (normal-to-mild atrophy on the left)
- parietal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precuneus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. parietal lobule (mild atrophy on the left and normal-to-mild atrophy on the right) and supramarginal gyrus (mild atrophy on the left)
For the subcortical structures:
- normal-to-mild bilateral amygdala atrophy
- moderate bilateral thalamus atrophy
- hippocampus atrophy (normal on the left, normal-to-mild on the right)
- accumbens atrophy (mild on the left, normal-to-mild on the right)
- putamen atrophy (normal-to-mild on the left, mild on the right)
- pallidum atrophy (normal on the left, normal-to-mild on the right)
- normal-to-mild bilateral caudate atrophy
- basal forebrain atrophy (normal on the left, normal-to-mild on the right)
- normal-to-mild bilateral ventral dc atrophy | BV |
ADNI_099_S_4104_MR_MPRAGE_br_raw_20110701121555888_20_S113393_I243001_dupl_4 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no signs of atrophy detected in the parietal lobe
- no observable atrophic alterations in the frontal lobe
- occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: occipital fusiform gyrus (mild atrophy on the left), middle occipital gyrus (mild atrophy on the left), cuneus (normal-to-mild atrophy on the left) and lingual gyrus (normal-to-mild atrophy on the left)
- no signs of atrophy detected in the limbic cortex
- temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: planum polare (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right) and inf. temporal gyrus (normal-to-mild atrophy on the left)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in central operculum (mild atrophy on the left and normal-to-mild atrophy on the right)
For the ventricles:
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- lateral ventricle maintains its normal volume without signs of enlargement
- no observable enlargement or abnormal growth in the 3rd ventricle
- normal-to-mild enlargement of the 4th ventricle
- normal-to-mild enlargement of the external csf
For the subcortical structures:
- no degenerative or atrophic changes noted in the pallidum
- hippocampus remains normal, with no signs of tissue loss
- caudate presents with a healthy appearance, free from atrophy
- putamen atrophy (normal-to-mild on the left, normal on the right)
- no evidence of atrophy or degeneration in the amygdala
- basal forebrain maintains its normal morphology without atrophic features
- normal-to-mild bilateral ventral dc atrophy
- no evidence of atrophy or degeneration in the thalamus
- accumbens remains normal, with no signs of tissue loss | CN |
NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492_dupl_4 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no evidence of atrophy or degeneration in the occipital lobe
- limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left)
- temporal lobe presents with a healthy appearance, free from atrophy
- insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (mild atrophy on the right)
- parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the left)
- frontal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), gyrus rectus (mild atrophy on the left and moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (moderate atrophy both left/right), medial frontal cortex (mild atrophy both left/right), middle frontal gyrus (moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left)
For the subcortical structures:
- putamen atrophy (severe on the left, mild on the right)
- accumbens atrophy (severe on the left, mild on the right)
- hippocampus atrophy (normal-to-mild on the left, normal on the right)
- severe bilateral caudate atrophy
- amygdala atrophy (mild on the left, normal-to-mild on the right)
- basal forebrain remains normal, with no signs of tissue loss
- thalamus atrophy (moderate on the left, normal-to-mild on the right)
- normal-to-mild bilateral ventral dc atrophy
- pallidum atrophy (moderate on the left, normal-to-mild on the right)
For the ventricles:
- inf. lateral ventricle enlargement (severe on the left, moderate on the right)
- severe enlargement of the external csf
- mild enlargement of the 3rd ventricle
- normal-to-mild enlargement of the 4th ventricle
- lateral ventricle enlargement (mild on the left, moderate on the right) | BV |
NIFD_1_S_0053_MR_T1_mprage_S3_DIS3D_br_raw_20170817095339381_67_S597254_I890544_dupl_2 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (moderate atrophy both left/right), parahippocampal gyrus (normal-to-mild atrophy both left/right) and middle cingulate gyrus (normal-to-mild atrophy on the left)
- no observable atrophic alterations in the parietal lobe
- moderate bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: fusiform gyrus (moderate atrophy on the left and severe atrophy on the right), planum temporale (normal-to-mild atrophy both left/right), inf. temporal gyrus (mild atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (severe atrophy on the left and moderate atrophy on the right) and planum polare (normal-to-mild atrophy on the right)
- insular cortex atrophy (mild on the left, moderate on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and severe atrophy on the right), posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and central operculum (normal-to-mild atrophy on the left)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in subcallosal area (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the right)
- no signs of atrophy detected in the occipital lobe
For the subcortical structures:
- no degenerative or atrophic changes noted in the basal forebrain
- severe bilateral accumbens atrophy
- no observable atrophic alterations in the ventral dc
- moderate bilateral hippocampus atrophy
- thalamus atrophy (normal-to-mild on the left, normal on the right)
- no pathological changes consistent with atrophy detected in the caudate
- severe bilateral amygdala atrophy
- pallidum atrophy (normal on the left, normal-to-mild on the right)
- putamen atrophy (mild on the left, normal-to-mild on the right)
For the ventricles:
- normal-to-mild enlargement of the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- normal-to-mild enlargement of the 3rd ventricle
- severe bilateral inf. lateral ventricle enlargement | SV |
NIFD_1_S_0040_MR_t1_mprage_S3_DIS3D_br_raw_20150522131343256_7_S261234_I494492_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens atrophy (severe on the left, mild on the right)
- normal-to-mild bilateral ventral dc atrophy
- severe bilateral caudate atrophy
- amygdala atrophy (mild on the left, normal-to-mild on the right)
- no evidence of atrophy or degeneration in the basal forebrain
- thalamus atrophy (moderate on the left, normal-to-mild on the right)
- pallidum atrophy (moderate on the left, normal-to-mild on the right)
- putamen atrophy (severe on the left, mild on the right)
- hippocampus atrophy (normal-to-mild on the left, normal on the right)
For the ventricles:
- normal-to-mild enlargement of the 4th ventricle
- lateral ventricle enlargement (mild on the left, moderate on the right)
- inf. lateral ventricle enlargement (severe on the left, moderate on the right)
- severe enlargement of the external csf
- mild enlargement of the 3rd ventricle
For the cerebral cortex:
- limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy both left/right), middle cingulate gyrus (normal-to-mild atrophy both left/right) and parahippocampal gyrus (normal-to-mild atrophy on the left)
- no evidence of atrophy or degeneration in the temporal lobe
- frontal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), gyrus rectus (mild atrophy on the left and moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), triangular inf. frontal gyrus (moderate atrophy both left/right), medial frontal cortex (mild atrophy both left/right), middle frontal gyrus (moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left)
- parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the left)
- occipital lobe appears structurally intact with no atrophic changes
- insular cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (normal-to-mild atrophy on the left) and parietal operculum (mild atrophy on the right) | BV |
ADNI_011_S_4827_MR_MPRAGE_br_raw_20120703085506250_153_S156389_I314042_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- amygdala atrophy (severe on the left, mild on the right)
- ventral dc presents with a healthy appearance, free from atrophy
- hippocampus atrophy (mild on the left, normal on the right)
- caudate atrophy (normal-to-mild on the left, normal on the right)
- no signs of atrophy detected in the basal forebrain
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- thalamus atrophy (mild on the left, normal-to-mild on the right)
- no observable atrophic alterations in the pallidum
- putamen atrophy (mild on the left, normal-to-mild on the right)
For the cerebral cortex:
- occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: occipital fusiform gyrus (normal-to-mild atrophy both left/right), middle occipital gyrus (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy on the right), inf. occipital gyrus (mild atrophy on the left) and calcarine cortex (normal-to-mild atrophy on the left)
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left)
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the left), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and gyrus rectus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus medial segment (moderate atrophy on the left and normal-to-mild atrophy on the right), angular gyrus (mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right), entorhinal area (normal-to-mild atrophy on the right), anterior cingulate gyrus (mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left)
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the right)
For the ventricles:
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- lateral ventricle appears structurally intact, with no evidence of enlargement
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- mild enlargement of the external csf
- no signs of enlargement detected in the 4th ventricle | AD |
ADNI_024_S_4158_MR_MPRAGE_br_raw_20110815114120024_16_S118583_I250350_dupl_1 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no abnormal enlargement observed in the external csf
- 3rd ventricle remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle is free from enlargement or excessive growth
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no enlargement observed in the 4th ventricle
For the cerebral cortex:
- frontal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: orbital inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (normal-to-mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), opercular inf. frontal gyrus (normal-to-mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), subcallosal area (normal-to-mild atrophy on the left) and precentral gyrus medial segment (normal-to-mild atrophy on the left)
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy both left/right), inf. temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the right)
- normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), parahippocampal gyrus (mild atrophy both left/right) and anterior cingulate gyrus (normal-to-mild atrophy on the right)
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy both left/right), angular gyrus (normal-to-mild atrophy on the left), postcentral gyrus (normal-to-mild atrophy on the right), postcentral gyrus medial segment (normal-to-mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy on the right) and precuneus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), occipital fusiform gyrus (normal-to-mild atrophy on the right), middle occipital gyrus (mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the left), cuneus (normal-to-mild atrophy on the left), lingual gyrus (normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the left) and occipital pole (normal-to-mild atrophy on the right)
- insular cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), posterior insula (normal-to-mild atrophy both left/right), parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and central operculum (normal-to-mild atrophy on the right)
For the subcortical structures:
- hippocampus appears structurally intact with no atrophic changes
- normal-to-mild bilateral caudate atrophy
- normal-to-mild bilateral putamen atrophy
- no signs of atrophy detected in the ventral dc
- normal-to-mild bilateral basal forebrain atrophy
- no evidence of atrophy or degeneration in the pallidum
- accumbens atrophy (mild on the left, normal-to-mild on the right)
- no signs of atrophy detected in the thalamus
- amygdala atrophy (normal on the left, normal-to-mild on the right) | CN |
ADNI_131_S_5138_MR_MPRAGE_br_raw_20130417113829938_29_S187196_I367565_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- caudate appears structurally intact with no atrophic changes
- pallidum presents with a healthy appearance, free from atrophy
- the basal forebrain shows no structural abnormalities indicative of atrophy
- amygdala atrophy (normal-to-mild on the left, normal on the right)
- the putamen shows no structural abnormalities indicative of atrophy
- normal-to-mild bilateral ventral dc atrophy
- accumbens maintains its normal morphology without atrophic features
- the hippocampus shows no structural abnormalities indicative of atrophy
- normal-to-mild bilateral thalamus atrophy
For the cerebral cortex:
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy both left/right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), transverse temporal gyrus (mild atrophy both left/right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), planum polare (normal-to-mild atrophy on the left), middle temporal gyrus (normal-to-mild atrophy on the right) and fusiform gyrus (normal-to-mild atrophy on the left)
- limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the right)
- insular cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (normal-to-mild atrophy both left/right) and anterior insula (normal-to-mild atrophy on the right)
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: sup. parietal lobule (mild atrophy on the left and moderate atrophy on the right), supramarginal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), postcentral gyrus (normal-to-mild atrophy on the left) and precuneus (normal-to-mild atrophy on the left)
- occipital lobe atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), lingual gyrus (normal-to-mild atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the right) and occipital pole (normal-to-mild atrophy on the right)
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), medial orbital gyrus (mild atrophy both left/right), precentral gyrus medial segment (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left), middle frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right), subcallosal area (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the right)
For the ventricles:
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the external csf
- no enlargement observed in the inf. lateral ventricle
- 4th ventricle maintains its normal volume without signs of enlargement
- no signs of enlargement detected in the lateral ventricle | AD |
NIFD_1_S_0096_MR_T1_mprage_S3_DIS3D_br_raw_20170817133934845_74_S598211_I891811_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no observable atrophic alterations in the basal forebrain
- hippocampus atrophy (normal-to-mild on the left, normal on the right)
- putamen presents with a healthy appearance, free from atrophy
- normal-to-mild bilateral pallidum atrophy
- amygdala atrophy (normal-to-mild on the left, normal on the right)
- normal-to-mild bilateral ventral dc atrophy
- thalamus atrophy (normal on the left, moderate on the right)
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- no evidence of atrophy or degeneration in the caudate
For the cerebral cortex:
- occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: lingual gyrus (normal-to-mild atrophy both left/right), sup. occipital gyrus (normal-to-mild atrophy both left/right), occipital pole (mild atrophy on the left and normal-to-mild atrophy on the right), calcarine cortex (normal-to-mild atrophy on the left) and inf. occipital gyrus (normal-to-mild atrophy on the right)
- parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: supramarginal gyrus (normal-to-mild atrophy on the right), angular gyrus (normal-to-mild atrophy on the left) and postcentral gyrus (normal-to-mild atrophy on the left)
- the limbic cortex shows no structural abnormalities indicative of atrophy
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left), supplementary motor cortex (normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the right)
- temporal lobe maintains its normal morphology without atrophic features
- normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: frontal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (mild atrophy on the right), central operculum (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the right)
For the ventricles:
- no abnormal enlargement observed in the external csf
- the lateral ventricle shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the 4th ventricle
- no enlargement observed in the inf. lateral ventricle
- normal-to-mild enlargement of the 3rd ventricle | BV |
NIFD_1_S_0176_MR_T1_mprage_S3_DIS3D_br_raw_20140831170526452_55_S228978_I441286_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- moderate bilateral thalamus atrophy
- mild bilateral putamen atrophy
- mild bilateral caudate atrophy
- normal-to-mild bilateral amygdala atrophy
- moderate bilateral ventral dc atrophy
- mild bilateral pallidum atrophy
- mild bilateral hippocampus atrophy
- normal-to-mild bilateral basal forebrain atrophy
- accumbens atrophy (normal on the left, normal-to-mild on the right)
For the ventricles:
- external csf remains within normal size parameters, with no enlargement detected
- no signs of enlargement detected in the 3rd ventricle
- no signs of enlargement detected in the lateral ventricle
- no pathological changes consistent with enlargement noted in the inf. lateral ventricle
- no pathological changes consistent with enlargement noted in the 4th ventricle
For the cerebral cortex:
- limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), middle cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (mild atrophy on the left) and entorhinal area (normal-to-mild atrophy on the left)
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy on the left and mild atrophy on the right), angular gyrus (normal-to-mild atrophy on the right), postcentral gyrus medial segment (normal-to-mild atrophy on the left) and sup. parietal lobule (normal-to-mild atrophy on the left)
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), planum polare (normal-to-mild atrophy on the right), inf. temporal gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (mild atrophy on the left)
- normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), lingual gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the right), cuneus (normal-to-mild atrophy on the right), inf. occipital gyrus (normal-to-mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the left) and occipital pole (normal-to-mild atrophy on the left)
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (mild atrophy both left/right), triangular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy both left/right), anterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (mild atrophy both left/right), sup. frontal gyrus (normal-to-mild atrophy both left/right), gyrus rectus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left), lateral orbital gyrus (normal-to-mild atrophy on the right) and medial orbital gyrus (normal-to-mild atrophy on the right)
- normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left/right), anterior insula (normal-to-mild atrophy on the left), posterior insula (mild atrophy on the right) and central operculum (normal-to-mild atrophy on the right) | CN |
ADNI_011_S_4827_MR_MPRAGE_br_raw_20120703085506250_153_S156389_I314042_dupl_4 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- normal-to-mild bilateral limbic cortex atrophy, with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right), entorhinal area (normal-to-mild atrophy on the right), anterior cingulate gyrus (mild atrophy on the right) and posterior cingulate gyrus (mild atrophy on the left)
- insular cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), frontal operculum (mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left)
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), anterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the left), triangular inf. frontal gyrus (normal-to-mild atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left) and gyrus rectus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy both left/right), temporal pole (normal-to-mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy on the left) and inf. temporal gyrus (normal-to-mild atrophy on the right)
- occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: occipital fusiform gyrus (normal-to-mild atrophy both left/right), middle occipital gyrus (normal-to-mild atrophy both left/right), cuneus (normal-to-mild atrophy on the right), inf. occipital gyrus (mild atrophy on the left) and calcarine cortex (normal-to-mild atrophy on the left)
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), postcentral gyrus medial segment (moderate atrophy on the left and normal-to-mild atrophy on the right), angular gyrus (mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the left)
For the ventricles:
- mild enlargement of the external csf
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle appears structurally intact, with no evidence of enlargement
- 4th ventricle maintains its normal volume without signs of enlargement
- 3rd ventricle is free from enlargement or excessive growth
For the subcortical structures:
- amygdala atrophy (severe on the left, mild on the right)
- no observable atrophic alterations in the basal forebrain
- putamen atrophy (mild on the left, normal-to-mild on the right)
- thalamus atrophy (mild on the left, normal-to-mild on the right)
- no degenerative or atrophic changes noted in the pallidum
- hippocampus atrophy (mild on the left, normal on the right)
- caudate atrophy (normal-to-mild on the left, normal on the right)
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- no degenerative or atrophic changes noted in the ventral dc | AD |
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776_dupl_4 | On a T1-weighted brain MRI we observed:
For the ventricles:
- the external csf shows no structural abnormalities indicative of enlargement
- mild enlargement of the 3rd ventricle
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- inf. lateral ventricle enlargement (severe on the left, moderate on the right)
- 4th ventricle remains within normal size parameters, with no enlargement detected
For the cerebral cortex:
- the occipital lobe shows no structural abnormalities indicative of atrophy
- temporal lobe remains normal, with no signs of tissue loss
- frontal lobe remains normal, with no signs of tissue loss
- limbic cortex remains normal, with no signs of tissue loss
- parietal lobe appears structurally intact with no atrophic changes
- the insular cortex shows no structural abnormalities indicative of atrophy
For the subcortical structures:
- caudate appears structurally intact with no atrophic changes
- the amygdala shows no structural abnormalities indicative of atrophy
- ventral dc appears structurally intact with no atrophic changes
- thalamus appears structurally intact with no atrophic changes
- pallidum remains normal, with no signs of tissue loss
- accumbens appears structurally intact with no atrophic changes
- hippocampus atrophy (normal-to-mild on the left, normal on the right)
- basal forebrain appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the putamen | AD |
NIFD_1_S_0238_MR_t1_mprage__br_raw_20160902144226204_127_S495765_I771932_dupl_4 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- basal forebrain presents with a healthy appearance, free from atrophy
- caudate presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the accumbens
- no signs of atrophy detected in the amygdala
- normal-to-mild bilateral hippocampus atrophy
- ventral dc remains normal, with no signs of tissue loss
- putamen maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the pallidum
- no degenerative or atrophic changes noted in the thalamus
For the ventricles:
- lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
- no abnormal enlargement observed in the 3rd ventricle
- normal-to-mild enlargement of the external csf
- no abnormal enlargement observed in the inf. lateral ventricle
- no enlargement observed in the 4th ventricle
For the cerebral cortex:
- no evidence of atrophy or degeneration in the occipital lobe
- temporal lobe presents with a healthy appearance, free from atrophy
- insular cortex maintains its normal morphology without atrophic features
- no pathological changes consistent with atrophy detected in the limbic cortex
- parietal lobe maintains its normal morphology without atrophic features
- no degenerative or atrophic changes noted in the frontal lobe | CN |
ADNI_024_S_4084_MR_MPRAGE_br_raw_20110620162005802_83_S112129_I241013_dupl_1 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no evidence of atrophy or degeneration in the hippocampus
- no pathological changes consistent with atrophy detected in the caudate
- no signs of atrophy detected in the amygdala
- normal-to-mild bilateral putamen atrophy
- no signs of atrophy detected in the accumbens
- no evidence of atrophy or degeneration in the thalamus
- no degenerative or atrophic changes noted in the ventral dc
- no observable atrophic alterations in the pallidum
- basal forebrain appears structurally intact with no atrophic changes
For the ventricles:
- the inf. lateral ventricle shows no structural abnormalities indicative of enlargement
- lateral ventricle remains within normal size parameters, with no enlargement detected
- 4th ventricle appears structurally intact, with no evidence of enlargement
- normal-to-mild enlargement of the external csf
- no observable enlargement or abnormal growth in the 3rd ventricle
For the cerebral cortex:
- temporal lobe remains normal, with no signs of tissue loss
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in orbital inf. frontal gyrus (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy on the left) and anterior orbital gyrus (mild atrophy on the right)
- no pathological changes consistent with atrophy detected in the occipital lobe
- the limbic cortex shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the insular cortex
- parietal lobe remains normal, with no signs of tissue loss | CN |
NIFD_1_S_0131_MR_T1_mprage_S3_DIS3D_br_raw_20130723102305083_133_S196174_I382122_dupl_2 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the frontal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy both left/right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), gyrus rectus (normal-to-mild atrophy on the left) and lateral orbital gyrus (normal-to-mild atrophy on the right)
- parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy both left/right) and supramarginal gyrus (normal-to-mild atrophy on the left)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in sup. occipital gyrus (mild atrophy on the right)
- limbic cortex remains normal, with no signs of tissue loss
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: temporal pole (normal-to-mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the left), inf. temporal gyrus (mild atrophy on the left), fusiform gyrus (normal-to-mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right) and central operculum (normal-to-mild atrophy on the right)
For the subcortical structures:
- accumbens atrophy (normal-to-mild on the left, normal on the right)
- the hippocampus shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the putamen
- no pathological changes consistent with atrophy detected in the thalamus
- no observable atrophic alterations in the caudate
- no observable atrophic alterations in the amygdala
- basal forebrain maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the ventral dc
- pallidum appears structurally intact with no atrophic changes
For the ventricles:
- no signs of enlargement detected in the external csf
- no signs of enlargement detected in the 4th ventricle
- lateral ventricle remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- 3rd ventricle remains within normal size parameters, with no enlargement detected | CN |
ADNI_073_S_4739_MR_MPRAGE_br_raw_20120516150253805_135_S150755_I304867_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- amygdala appears structurally intact with no atrophic changes
- normal-to-mild bilateral caudate atrophy
- ventral dc remains normal, with no signs of tissue loss
- putamen maintains its normal morphology without atrophic features
- hippocampus remains normal, with no signs of tissue loss
- the basal forebrain shows no structural abnormalities indicative of atrophy
- thalamus atrophy (normal-to-mild on the left, normal on the right)
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- pallidum appears structurally intact with no atrophic changes
For the cerebral cortex:
- insular cortex appears structurally intact with no atrophic changes
- occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: cuneus (mild atrophy on the left and normal-to-mild atrophy on the right), calcarine cortex (normal-to-mild atrophy on the left), occipital fusiform gyrus (normal-to-mild atrophy on the left) and middle occipital gyrus (normal-to-mild atrophy on the left)
- no observable atrophic alterations in the limbic cortex
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and supramarginal gyrus (normal-to-mild atrophy on the right)
- temporal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (normal-to-mild atrophy both left/right), fusiform gyrus (mild atrophy on the left) and temporal pole (mild atrophy on the left)
- frontal lobe remains normal, with no signs of tissue loss
For the ventricles:
- lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
- mild enlargement of the external csf
- 3rd ventricle is free from enlargement or excessive growth
- inf. lateral ventricle appears structurally intact, with no evidence of enlargement
- 4th ventricle appears structurally intact, with no evidence of enlargement | CN |
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776_dupl_2 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- hippocampus atrophy (normal-to-mild on the left, normal on the right)
- no degenerative or atrophic changes noted in the accumbens
- no degenerative or atrophic changes noted in the caudate
- the putamen shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the pallidum
- no pathological changes consistent with atrophy detected in the ventral dc
- no pathological changes consistent with atrophy detected in the basal forebrain
- the amygdala shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the thalamus
For the ventricles:
- external csf is free from enlargement or excessive growth
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- mild enlargement of the 3rd ventricle
- inf. lateral ventricle enlargement (severe on the left, moderate on the right)
For the cerebral cortex:
- no evidence of atrophy or degeneration in the parietal lobe
- no evidence of atrophy or degeneration in the insular cortex
- no observable atrophic alterations in the occipital lobe
- frontal lobe maintains its normal morphology without atrophic features
- temporal lobe appears structurally intact with no atrophic changes
- limbic cortex maintains its normal morphology without atrophic features | AD |
NIFD_2_S_0014_MR_MT1__GradWarp__N3m_Br_20111229191004875_S134530_I274739_dupl_2 | On a T1-weighted brain MRI we observed:
For the ventricles:
- severe bilateral lateral ventricle enlargement
- inf. lateral ventricle enlargement (severe on the left, moderate on the right)
- severe enlargement of the external csf
- mild enlargement of the 4th ventricle
- mild enlargement of the 3rd ventricle
For the subcortical structures:
- no degenerative or atrophic changes noted in the basal forebrain
- hippocampus atrophy (normal on the left, normal-to-mild on the right)
- amygdala atrophy (mild on the left, normal-to-mild on the right)
- accumbens atrophy (severe on the left, moderate on the right)
- putamen atrophy (mild on the left, moderate on the right)
- mild bilateral pallidum atrophy
- moderate bilateral caudate atrophy
- normal-to-mild bilateral thalamus atrophy
- no degenerative or atrophic changes noted in the ventral dc
For the cerebral cortex:
- parietal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: precuneus (normal-to-mild atrophy both left/right), sup. parietal lobule (mild atrophy on the left and normal-to-mild atrophy on the right), supramarginal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and angular gyrus (mild atrophy on the left)
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right), fusiform gyrus (normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the right) and transverse temporal gyrus (normal-to-mild atrophy on the right)
- limbic cortex atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle cingulate gyrus (normal-to-mild atrophy on the right)
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and moderate atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the left), lateral orbital gyrus (mild atrophy on the left), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right) and precentral gyrus (normal-to-mild atrophy on the right)
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in cuneus (mild atrophy on the left and normal-to-mild atrophy on the right) and middle occipital gyrus (normal-to-mild atrophy both left/right)
- insular cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), central operculum (mild atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (mild atrophy on the right), posterior insula (normal-to-mild atrophy on the right) and frontal operculum (normal-to-mild atrophy on the right) | BV |
NIFD_1_S_0212_MR_T1_mprage_S3_DIS3D_br_raw_20170817105545257_129_S597537_I890918_dupl_5 | On a T1-weighted brain MRI we observed:
For the ventricles:
- inf. lateral ventricle is free from enlargement or excessive growth
- normal-to-mild bilateral lateral ventricle enlargement
- normal-to-mild enlargement of the 4th ventricle
- external csf remains within normal size parameters, with no enlargement detected
- mild enlargement of the 3rd ventricle
For the cerebral cortex:
- the temporal lobe shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the insular cortex
- limbic cortex presents with a healthy appearance, free from atrophy
- parietal lobe appears structurally intact with no atrophic changes
- frontal lobe appears structurally intact with no atrophic changes
- occipital lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: cuneus (normal-to-mild atrophy on the left), inf. occipital gyrus (mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the left) and calcarine cortex (normal-to-mild atrophy on the left)
For the subcortical structures:
- the amygdala shows no structural abnormalities indicative of atrophy
- accumbens atrophy (normal-to-mild on the left, normal on the right)
- mild bilateral pallidum atrophy
- putamen remains normal, with no signs of tissue loss
- normal-to-mild bilateral ventral dc atrophy
- thalamus remains normal, with no signs of tissue loss
- no observable atrophic alterations in the hippocampus
- normal-to-mild bilateral caudate atrophy
- the basal forebrain shows no structural abnormalities indicative of atrophy | CN |
ADNI_006_S_4485_MR_MPRAGE_br_raw_20120201124039752_139_S139148_I281882_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the thalamus shows no structural abnormalities indicative of atrophy
- caudate presents with a healthy appearance, free from atrophy
- the amygdala shows no structural abnormalities indicative of atrophy
- the pallidum shows no structural abnormalities indicative of atrophy
- ventral dc appears structurally intact with no atrophic changes
- no signs of atrophy detected in the putamen
- no evidence of atrophy or degeneration in the hippocampus
- basal forebrain presents with a healthy appearance, free from atrophy
- accumbens remains normal, with no signs of tissue loss
For the cerebral cortex:
- no evidence of atrophy or degeneration in the insular cortex
- no evidence of atrophy or degeneration in the temporal lobe
- no observable atrophic alterations in the occipital lobe
- the parietal lobe shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the frontal lobe
- limbic cortex remains normal, with no signs of tissue loss
For the ventricles:
- no observable enlargement or abnormal growth in the 3rd ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- moderate enlargement of the 4th ventricle
- no abnormal enlargement observed in the inf. lateral ventricle
- external csf appears structurally intact, with no evidence of enlargement | CN |
NIFD_1_S_0339_MR_T1_mprage_S3_DIS3D_br_raw_20170629002457144_144_S577807_I867541_dupl_3 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), middle occipital gyrus (normal-to-mild atrophy on the right), inf. occipital gyrus (mild atrophy on the left) and cuneus (normal-to-mild atrophy on the right)
- limbic cortex atrophy (mild on the left, moderate on the right), with focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and moderate atrophy on the right), anterior cingulate gyrus (mild atrophy on the left and moderate atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy on the right) and posterior cingulate gyrus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (normal-to-mild atrophy both left/right), gyrus rectus (mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left and moderate atrophy on the right), middle frontal gyrus (normal-to-mild atrophy both left/right), medial orbital gyrus (mild atrophy on the left and moderate atrophy on the right), subcallosal area (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left), anterior orbital gyrus (normal-to-mild atrophy on the right) and lateral orbital gyrus (normal-to-mild atrophy on the right)
- temporal lobe atrophy (moderate on the left, severe on the right), with focal volume loss observed in the following subregions: fusiform gyrus (mild atrophy on the left and moderate atrophy on the right), planum polare (mild atrophy both left/right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild atrophy both left/right), temporal pole (severe atrophy both left/right) and middle temporal gyrus (severe atrophy on the right)
- insular cortex atrophy (mild on the left, moderate on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and moderate atrophy on the right), posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right), central operculum (mild atrophy both left/right), frontal operculum (normal-to-mild atrophy both left/right) and parietal operculum (normal-to-mild atrophy on the left and mild atrophy on the right)
- parietal lobe atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right) and postcentral gyrus medial segment (normal-to-mild atrophy on the left)
For the subcortical structures:
- normal-to-mild bilateral ventral dc atrophy
- putamen atrophy (mild on the left, moderate on the right)
- normal-to-mild bilateral thalamus atrophy
- severe bilateral amygdala atrophy
- no degenerative or atrophic changes noted in the basal forebrain
- pallidum atrophy (normal-to-mild on the left, mild on the right)
- accumbens atrophy (moderate on the left, severe on the right)
- caudate atrophy (normal on the left, mild on the right)
- severe bilateral hippocampus atrophy
For the ventricles:
- external csf maintains its normal volume without signs of enlargement
- no pathological changes consistent with enlargement noted in the lateral ventricle
- inf. lateral ventricle enlargement (moderate on the left, severe on the right)
- 3rd ventricle is free from enlargement or excessive growth
- 4th ventricle maintains its normal volume without signs of enlargement | SV |
NIFD_1_S_0024_MR_t1_mprage_S7_DIS3D_br_raw_20110203091851798_6_S98780_I215642_dupl_5 | On a T1-weighted brain MRI we observed:
For the ventricles:
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- no observable enlargement or abnormal growth in the external csf
- no observable enlargement or abnormal growth in the lateral ventricle
- no abnormal enlargement observed in the 4th ventricle
For the subcortical structures:
- amygdala atrophy (mild on the left, normal-to-mild on the right)
- hippocampus maintains its normal morphology without atrophic features
- no evidence of atrophy or degeneration in the ventral dc
- no degenerative or atrophic changes noted in the thalamus
- normal-to-mild bilateral caudate atrophy
- putamen atrophy (mild on the left, normal-to-mild on the right)
- no evidence of atrophy or degeneration in the basal forebrain
- accumbens atrophy (mild on the left, normal-to-mild on the right)
- pallidum atrophy (normal-to-mild on the left, normal on the right)
For the cerebral cortex:
- normal-to-mild bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy both left/right), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy both left/right), lateral orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precentral gyrus (normal-to-mild atrophy both left/right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the right), posterior orbital gyrus (normal-to-mild atrophy on the left), precentral gyrus medial segment (moderate atrophy on the left), medial orbital gyrus (normal-to-mild atrophy on the left) and supplementary motor cortex (normal-to-mild atrophy on the right)
- temporal lobe atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), temporal pole (moderate atrophy on the left and mild atrophy on the right), planum polare (normal-to-mild atrophy on the left), planum temporale (normal-to-mild atrophy on the left), sup. temporal gyrus (mild atrophy on the left), transverse temporal gyrus (normal-to-mild atrophy on the right) and middle temporal gyrus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: central operculum (mild atrophy both left/right), anterior insula (normal-to-mild atrophy on the left) and parietal operculum (normal-to-mild atrophy on the left)
- occipital lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: occipital pole (normal-to-mild atrophy on the left and mild atrophy on the right), calcarine cortex (mild atrophy on the right), middle occipital gyrus (normal-to-mild atrophy on the left), occipital fusiform gyrus (normal-to-mild atrophy on the left) and sup. occipital gyrus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: postcentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), angular gyrus (normal-to-mild atrophy on the right), sup. parietal lobule (normal-to-mild atrophy on the left) and supramarginal gyrus (normal-to-mild atrophy on the right)
- limbic cortex atrophy (mild on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: entorhinal area (normal-to-mild atrophy both left/right), posterior cingulate gyrus (normal-to-mild atrophy both left/right), anterior cingulate gyrus (normal-to-mild atrophy on the left) and middle cingulate gyrus (normal-to-mild atrophy on the left) | CN |
ADNI_135_S_5275_MR_MPRAGE_br_raw_20130805125009417_8_S197268_I384344_dupl_5 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no signs of enlargement detected in the 4th ventricle
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- lateral ventricle enlargement (mild on the left, moderate on the right)
- inf. lateral ventricle enlargement (normal on the left, normal-to-mild on the right)
- mild enlargement of the external csf
For the subcortical structures:
- putamen atrophy (normal-to-mild on the left, normal on the right)
- basal forebrain maintains its normal morphology without atrophic features
- the ventral dc shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the pallidum
- accumbens appears structurally intact with no atrophic changes
- no signs of atrophy detected in the thalamus
- no evidence of atrophy or degeneration in the hippocampus
- no evidence of atrophy or degeneration in the caudate
- the amygdala shows no structural abnormalities indicative of atrophy
For the cerebral cortex:
- insular cortex presents with a healthy appearance, free from atrophy
- limbic cortex remains normal, with no signs of tissue loss
- the frontal lobe shows no structural abnormalities indicative of atrophy
- no signs of atrophy detected in the occipital lobe
- no signs of atrophy detected in the temporal lobe
- parietal lobe remains normal, with no signs of tissue loss | AD |
NIFD_1_S_0279_MR_t1_mprage__br_raw_20160903204551965_44_S496713_I773020_dupl_1 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- insular cortex maintains its normal morphology without atrophic features
- normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the right), cuneus (normal-to-mild atrophy on the left) and middle occipital gyrus (normal-to-mild atrophy on the left)
- limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), angular gyrus (normal-to-mild atrophy on the right) and postcentral gyrus medial segment (normal-to-mild atrophy on the left)
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the left)
- frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: medial frontal cortex (mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the left)
For the subcortical structures:
- normal-to-mild bilateral ventral dc atrophy
- caudate atrophy (normal-to-mild on the left, normal on the right)
- normal-to-mild bilateral hippocampus atrophy
- thalamus appears structurally intact with no atrophic changes
- normal-to-mild bilateral amygdala atrophy
- no degenerative or atrophic changes noted in the accumbens
- putamen atrophy (normal-to-mild on the left, normal on the right)
- no pathological changes consistent with atrophy detected in the pallidum
- normal-to-mild bilateral basal forebrain atrophy
For the ventricles:
- the 4th ventricle shows no structural abnormalities indicative of enlargement
- no signs of enlargement detected in the 3rd ventricle
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- no enlargement observed in the external csf
- lateral ventricle remains within normal size parameters, with no enlargement detected | CN |
ADNI_072_S_4103_MR_MPRAGE_br_raw_20110721105250665_38_S115543_I245969_dupl_5 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild bilateral caudate atrophy
- amygdala atrophy (normal-to-mild on the left, mild on the right)
- moderate bilateral hippocampus atrophy
- mild bilateral pallidum atrophy
- mild bilateral ventral dc atrophy
- mild bilateral thalamus atrophy
- normal-to-mild bilateral basal forebrain atrophy
- mild bilateral putamen atrophy
- accumbens atrophy (mild on the left, moderate on the right)
For the cerebral cortex:
- mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: cuneus (normal-to-mild atrophy on the left and mild atrophy on the right), lingual gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy both left/right), inf. occipital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), occipital pole (mild atrophy on the left and normal-to-mild atrophy on the right) and middle occipital gyrus (moderate atrophy on the right)
- moderate bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), postcentral gyrus (moderate atrophy both left/right), precuneus (moderate atrophy on the left and mild atrophy on the right), sup. parietal lobule (moderate atrophy on the left and mild atrophy on the right), supramarginal gyrus (mild atrophy both left/right) and postcentral gyrus medial segment (normal-to-mild atrophy on the right)
- temporal lobe atrophy (moderate on the left, mild on the right), with focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy both left/right), planum polare (moderate atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy both left/right), transverse temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), temporal pole (normal-to-mild atrophy on the left and mild atrophy on the right) and planum temporale (mild atrophy on the left)
- moderate bilateral insular cortex atrophy, with focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), posterior insula (mild atrophy on the left and moderate atrophy on the right), central operculum (moderate atrophy on the left and mild atrophy on the right), parietal operculum (mild atrophy both left/right) and frontal operculum (normal-to-mild atrophy on the right)
- limbic cortex atrophy (normal-to-mild on the left, mild on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), posterior cingulate gyrus (mild atrophy both left/right), parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), entorhinal area (normal-to-mild atrophy on the left) and anterior cingulate gyrus (mild atrophy on the right)
- moderate bilateral frontal lobe atrophy, with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), gyrus rectus (mild atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy both left/right), triangular inf. frontal gyrus (mild atrophy both left/right), middle frontal gyrus (mild atrophy both left/right), medial orbital gyrus (mild atrophy both left/right), posterior orbital gyrus (normal-to-mild atrophy both left/right), precentral gyrus (severe atrophy on the left and moderate atrophy on the right), precentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), subcallosal area (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (normal-to-mild atrophy both left/right), medial frontal cortex (mild atrophy on the right), lateral orbital gyrus (mild atrophy on the right) and sup. frontal gyrus medial segment (normal-to-mild atrophy on the left)
For the ventricles:
- no abnormal enlargement observed in the 4th ventricle
- lateral ventricle appears structurally intact, with no evidence of enlargement
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- no enlargement observed in the external csf
- inf. lateral ventricle maintains its normal volume without signs of enlargement | CN |
ADNI_011_S_4906_MR_MPRAGE_br_raw_20120904143307512_81_S165942_I330056_dupl_1 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the parietal lobe
- no evidence of atrophy or degeneration in the limbic cortex
- no pathological changes consistent with atrophy detected in the frontal lobe
- the temporal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in fusiform gyrus (normal-to-mild atrophy on the left) and sup. temporal gyrus (mild atrophy on the right)
- no evidence of atrophy or degeneration in the occipital lobe
- insular cortex appears structurally intact with no atrophic changes
For the subcortical structures:
- no signs of atrophy detected in the basal forebrain
- pallidum presents with a healthy appearance, free from atrophy
- ventral dc presents with a healthy appearance, free from atrophy
- thalamus maintains its normal morphology without atrophic features
- hippocampus atrophy (mild on the left, normal on the right)
- no observable atrophic alterations in the caudate
- no signs of atrophy detected in the accumbens
- the amygdala shows no structural abnormalities indicative of atrophy
- putamen remains normal, with no signs of tissue loss
For the ventricles:
- no observable enlargement or abnormal growth in the 4th ventricle
- the 3rd ventricle shows no structural abnormalities indicative of enlargement
- inf. lateral ventricle enlargement (moderate on the left, normal on the right)
- normal-to-mild enlargement of the external csf
- lateral ventricle enlargement (mild on the left, normal-to-mild on the right) | AD |
NIFD_1_S_0237_MR_t1_mprage__br_raw_20160902142657075_120_S495712_I771873_dupl_3 | On a T1-weighted brain MRI we observed:
For the ventricles:
- no signs of enlargement detected in the external csf
- no abnormal enlargement observed in the inf. lateral ventricle
- no pathological changes consistent with enlargement noted in the lateral ventricle
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- the 4th ventricle shows no structural abnormalities indicative of enlargement
For the subcortical structures:
- normal-to-mild bilateral caudate atrophy
- basal forebrain remains normal, with no signs of tissue loss
- no observable atrophic alterations in the thalamus
- no degenerative or atrophic changes noted in the hippocampus
- putamen presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the pallidum
- amygdala appears structurally intact with no atrophic changes
- the ventral dc shows no structural abnormalities indicative of atrophy
- accumbens atrophy (normal on the left, normal-to-mild on the right)
For the cerebral cortex:
- no evidence of atrophy or degeneration in the occipital lobe
- frontal lobe remains normal, with no signs of tissue loss
- normal-to-mild bilateral parietal lobe atrophy, with focal volume loss observed in the following subregions: angular gyrus (normal-to-mild atrophy both left/right), precuneus (normal-to-mild atrophy both left/right) and postcentral gyrus (normal-to-mild atrophy on the right)
- no pathological changes consistent with atrophy detected in the insular cortex
- no pathological changes consistent with atrophy detected in the limbic cortex
- the temporal lobe shows no structural abnormalities indicative of atrophy | CN |
ADNI_024_S_5054_MR_MPRAGE_br_raw_20121220180216980_73_S178405_I352573_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no evidence of atrophy or degeneration in the caudate
- no degenerative or atrophic changes noted in the putamen
- the basal forebrain shows no structural abnormalities indicative of atrophy
- the amygdala shows no structural abnormalities indicative of atrophy
- no degenerative or atrophic changes noted in the thalamus
- accumbens maintains its normal morphology without atrophic features
- pallidum remains normal, with no signs of tissue loss
- no pathological changes consistent with atrophy detected in the hippocampus
- no signs of atrophy detected in the ventral dc
For the cerebral cortex:
- the frontal lobe shows no structural abnormalities indicative of atrophy
- temporal lobe presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the insular cortex
- the occipital lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in occipital fusiform gyrus (normal-to-mild atrophy both left/right) and occipital pole (mild atrophy on the right)
- no evidence of atrophy or degeneration in the parietal lobe
- no signs of atrophy detected in the limbic cortex
For the ventricles:
- 4th ventricle remains within normal size parameters, with no enlargement detected
- the external csf shows no structural abnormalities indicative of enlargement
- inf. lateral ventricle enlargement (moderate on the left, severe on the right)
- lateral ventricle enlargement (mild on the left, normal-to-mild on the right)
- normal-to-mild enlargement of the 3rd ventricle | AD |
NIFD_2_S_0002_MR_MT1__GradWarp__N3m_Br_20111229184614074_S133938_I274719_dupl_2 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- caudate atrophy (moderate on the left, severe on the right)
- hippocampus atrophy (normal-to-mild on the left, mild on the right)
- amygdala maintains its normal morphology without atrophic features
- putamen atrophy (mild on the left, severe on the right)
- thalamus atrophy (normal on the left, mild on the right)
- accumbens atrophy (mild on the left, severe on the right)
- no pathological changes consistent with atrophy detected in the basal forebrain
- ventral dc atrophy (normal on the left, normal-to-mild on the right)
- pallidum atrophy (mild on the left, severe on the right)
For the cerebral cortex:
- no pathological changes consistent with atrophy detected in the occipital lobe
- insular cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and severe atrophy on the right), frontal operculum (normal-to-mild atrophy on the left and moderate atrophy on the right), posterior insula (normal-to-mild atrophy on the right) and central operculum (normal-to-mild atrophy on the right)
- limbic cortex atrophy (normal on the left, mild on the right), with focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and moderate atrophy on the right) and parahippocampal gyrus (normal-to-mild atrophy on the right)
- frontal lobe atrophy (normal-to-mild on the left, severe on the right), with focal volume loss observed in the following subregions: frontal pole (mild atrophy on the left and moderate atrophy on the right), gyrus rectus (mild atrophy on the left and severe atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle frontal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), anterior orbital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), lateral orbital gyrus (mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and moderate atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the right), medial frontal cortex (moderate atrophy on the right), posterior orbital gyrus (moderate atrophy on the right), sup. frontal gyrus (severe atrophy on the right) and precentral gyrus (normal-to-mild atrophy on the right)
- temporal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: middle temporal gyrus (mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the right) and temporal pole (mild atrophy on the right)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in angular gyrus (mild atrophy on the right) and supramarginal gyrus (normal-to-mild atrophy on the right)
For the ventricles:
- mild enlargement of the external csf
- lateral ventricle enlargement (normal-to-mild on the left, moderate on the right)
- no pathological changes consistent with enlargement noted in the 4th ventricle
- moderate enlargement of the 3rd ventricle
- inf. lateral ventricle enlargement (mild on the left, severe on the right) | BV |
ADNI_130_S_5059_MR_MPRAGE_br_raw_20130212105012862_33_S182011_I358776_dupl_1 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens presents with a healthy appearance, free from atrophy
- no signs of atrophy detected in the ventral dc
- caudate maintains its normal morphology without atrophic features
- the putamen shows no structural abnormalities indicative of atrophy
- the pallidum shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the basal forebrain
- hippocampus atrophy (normal-to-mild on the left, normal on the right)
- no pathological changes consistent with atrophy detected in the thalamus
- no degenerative or atrophic changes noted in the amygdala
For the cerebral cortex:
- no observable atrophic alterations in the occipital lobe
- no evidence of atrophy or degeneration in the insular cortex
- frontal lobe presents with a healthy appearance, free from atrophy
- temporal lobe presents with a healthy appearance, free from atrophy
- no evidence of atrophy or degeneration in the limbic cortex
- no observable atrophic alterations in the parietal lobe
For the ventricles:
- mild enlargement of the 3rd ventricle
- lateral ventricle enlargement (normal-to-mild on the left, normal on the right)
- external csf remains within normal size parameters, with no enlargement detected
- inf. lateral ventricle enlargement (severe on the left, moderate on the right)
- 4th ventricle is free from enlargement or excessive growth | AD |
NIFD_1_S_0288_MR_t1_mprage__br_raw_20170814180736340_14_S594408_I886878_dupl_3 | On a T1-weighted brain MRI we observed:
For the subcortical structures:
- amygdala presents with a healthy appearance, free from atrophy
- hippocampus atrophy (normal-to-mild on the left, normal on the right)
- accumbens atrophy (normal on the left, normal-to-mild on the right)
- thalamus presents with a healthy appearance, free from atrophy
- normal-to-mild bilateral caudate atrophy
- pallidum appears structurally intact with no atrophic changes
- no evidence of atrophy or degeneration in the basal forebrain
- no observable atrophic alterations in the ventral dc
- no signs of atrophy detected in the putamen
For the cerebral cortex:
- parietal lobe presents with a healthy appearance, free from atrophy
- the occipital lobe shows no structural abnormalities indicative of atrophy
- no pathological changes consistent with atrophy detected in the frontal lobe
- no pathological changes consistent with atrophy detected in the temporal lobe
- no evidence of atrophy or degeneration in the limbic cortex
- insular cortex presents with a healthy appearance, free from atrophy
For the ventricles:
- lateral ventricle appears structurally intact, with no evidence of enlargement
- 3rd ventricle maintains its normal volume without signs of enlargement
- external csf is free from enlargement or excessive growth
- no observable enlargement or abnormal growth in the inf. lateral ventricle
- normal-to-mild enlargement of the 4th ventricle | CN |
NIFD_1_S_0235_MR_t1_mprage__br_raw_20160902135026421_139_S495650_I771798_dupl_3 | On a T1-weighted brain MRI we observed:
For the ventricles:
- inf. lateral ventricle remains within normal size parameters, with no enlargement detected
- no pathological changes consistent with enlargement noted in the 3rd ventricle
- no signs of enlargement detected in the external csf
- 4th ventricle appears structurally intact, with no evidence of enlargement
- no observable enlargement or abnormal growth in the lateral ventricle
For the cerebral cortex:
- no evidence of atrophy or degeneration in the temporal lobe
- frontal lobe presents with a healthy appearance, free from atrophy
- no degenerative or atrophic changes noted in the occipital lobe
- no degenerative or atrophic changes noted in the parietal lobe
- no evidence of atrophy or degeneration in the limbic cortex
- no evidence of atrophy or degeneration in the insular cortex
For the subcortical structures:
- no degenerative or atrophic changes noted in the putamen
- no degenerative or atrophic changes noted in the hippocampus
- amygdala appears structurally intact with no atrophic changes
- no degenerative or atrophic changes noted in the basal forebrain
- no signs of atrophy detected in the pallidum
- no observable atrophic alterations in the thalamus
- ventral dc maintains its normal morphology without atrophic features
- caudate remains normal, with no signs of tissue loss
- no signs of atrophy detected in the accumbens | CN |
NIFD_1_S_0279_MR_t1_mprage__br_raw_20160903204551965_44_S496713_I773020_dupl_2 | On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- normal-to-mild bilateral temporal lobe atrophy, with focal volume loss observed in the following subregions: inf. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (normal-to-mild atrophy both left/right), sup. temporal gyrus (normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the right) and temporal pole (normal-to-mild atrophy on the left)
- the insular cortex shows no structural abnormalities indicative of atrophy
- limbic cortex atrophy (normal-to-mild on the left, normal on the right), with focal volume loss observed in the following subregions: middle cingulate gyrus (normal-to-mild atrophy both left/right)
- frontal lobe atrophy (normal on the left, normal-to-mild on the right), with focal volume loss observed in the following subregions: medial frontal cortex (mild atrophy both left/right), precentral gyrus (normal-to-mild atrophy both left/right), subcallosal area (normal-to-mild atrophy both left/right), lateral orbital gyrus (normal-to-mild atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left), frontal pole (normal-to-mild atrophy on the right), gyrus rectus (normal-to-mild atrophy on the left), orbital inf. frontal gyrus (normal-to-mild atrophy on the right) and sup. frontal gyrus (normal-to-mild atrophy on the left)
- normal-to-mild bilateral occipital lobe atrophy, with focal volume loss observed in the following subregions: calcarine cortex (normal-to-mild atrophy both left/right), inf. occipital gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), occipital fusiform gyrus (normal-to-mild atrophy on the left), sup. occipital gyrus (normal-to-mild atrophy on the right), cuneus (normal-to-mild atrophy on the left) and middle occipital gyrus (normal-to-mild atrophy on the left)
- the parietal lobe does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), angular gyrus (normal-to-mild atrophy on the right) and postcentral gyrus medial segment (normal-to-mild atrophy on the left)
For the ventricles:
- no abnormal enlargement observed in the lateral ventricle
- 3rd ventricle appears structurally intact, with no evidence of enlargement
- inf. lateral ventricle maintains its normal volume without signs of enlargement
- no observable enlargement or abnormal growth in the 4th ventricle
- no signs of enlargement detected in the external csf
For the subcortical structures:
- putamen atrophy (normal-to-mild on the left, normal on the right)
- the accumbens shows no structural abnormalities indicative of atrophy
- no evidence of atrophy or degeneration in the thalamus
- normal-to-mild bilateral amygdala atrophy
- normal-to-mild bilateral ventral dc atrophy
- pallidum remains normal, with no signs of tissue loss
- normal-to-mild bilateral hippocampus atrophy
- normal-to-mild bilateral basal forebrain atrophy
- caudate atrophy (normal-to-mild on the left, normal on the right) | CN |
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