PMID
int64 27.8M
36.2M
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34,695,294 |
respons bimetal agzno alloy nanoparticl urea morpholog physiolog attribut wheat wheat triticum aestivum l import stapl food crop global accord econom survey agricultur sector pakistan grew wheat account agricultur gdp product fell short target wheat requir benefici tie improv effici help modern technolog nanotechnolog modifi convent agricultur practic stimul agent plant growth green bimetal agzno alloy nanoparticl nps synthesis salt reduc moringa oleifera characteris uv visibl spectroscopi scan electron microscopi energi dispers x ray spectroscopi studi herein differ concentr urea agzno alloy nps appli exogen wheat plant pakistan galaxi signific effect mgl urea ppm agzno alloy nps observ morpholog wheat maximum increas plant length leaf area plant fresh weight plant dri weight physiolog paramet relat water content membran stabil index shown maximum increas chlorophyl b total chlorophyl content tcc show maximum increas respect evid morpho physiolog respons urea green synthesis alloy nps wheat varieti report
|
D053768;D053758;D015034
|
T197;T121;T073
|
34,695,293 |
fabric microcapsul core shell structur oral deliveri dual drug real time comput tomographi imag although multidrug combin effect therapeut strategi serious diseas clinic practic therapeut effect may reduc conflict medicin certain case henc urgent need develop singl drug carrier precis multidrug deliveri avoid interfer revers coordin method report fabric doubl layer barium sulphat microcapsul dl bs ms two drug separ load simultan addit bs nanoclust synthesis situ insid dl bs mss real time comput tomographi ct imag result show dl bs mss particl size approxim mm exhibit uniform sphere bs nanoclust high x ray attenu coeffici retent dl bs mss digest tract could monitor ct imag real time import core shell structur dl bs mss encapsul two differ drug could releas spatiotempor order acid stomach environ synthesi dl bs mss core shell structur real time imag perform provid ideal carrier oral administr multipl drug simultan load sequenti releas
|
D004337;D014057
|
T122;T060
|
34,695,292 |
mutant combin lycopen cyclas caroten hydroxylas homoeolog increas caroten accumul endosperm tetraploid wheat triticum turgidum l grain grain tetraploid wheat triticum turgidum l main accumul non provitamin carotenoid lutein low natur variat provitamin caroten wheat access necessit altern strategi provitamin biofortif lycopen cyclas lcye caroten hydroxylas hyd function divert carbon caroten lutein biosynthesi catalyz turnov caroten xanthophyl respect howev contribut lcye hyd gene homoeolog carotenoid metabol manipul increas caroten tetraploid wheat endosperm flour current unclear isol loss function target induc local lesion genom till mutant lcye hyd homoeolog generat higher order mutant combin lcye lcye b hyd hyd b hyd hyd b lcye hyd hyd b lcye b hyd hyd b lcye lcye b hyd hyd b achiev signific increas caroten endosperm lcye hyd hyd b exhibit compar photosynthet perform light respons control plant compar analysi carotenoid profil suggest elimin hyd homoeolog suffici prevent caroten convers xanthophyl endosperm without compromis xanthophyl product leav caroten deriv xanthophyl like subject differenti catalysi mechan veget tissu grain carotenoid gene express analys also suggest low lcye b express endosperm adequ lutein product absenc lcye result demonstr success provitamin biofortif use till mutant also provid roadmap guid gene edit base approach hexaploid wheat
|
D019753;D006899;D014908;D019207
|
T121;T126;T002;T168;T116;T127;T109
|
34,695,291 |
bat ectoparasit nycteribiida spinturnicida carri divers novel bartonella genotyp china bartonella speci facult intracellular bacteria recogn worldwid emerg zoonot pathogen bartonella isol identifi polymeras chain reaction pcr bat ectoparasit worldwid wherea associ scarc especi asia studi retrospect analysi frozen sampl carri identifi genet divers bartonella bat ectoparasit investig relationship bartonella carri bat ectoparasit bat ectoparasit bat fli bat mite collect cave hubei provinc central china may juli bartonella screen pcr amplif sequenc three gene glta rpob ftsz bat bat fli bat mite carri divers novel bartonella genotyp high preval share bartonella genotyp bat bat fli bat mite indic potenti role bat fli bat mite vector bartonella higher genet divers bartonella bat fli bat might due vertic transmiss bacterium bat fli therefor bat fli might also act reservoir bartonella addit human pathogen b mayotimonesi identifi bat ectoparasit expand knowledg geograph distribut bacterium suggest potenti bat origin bat fli bat mite play import role mainten transmiss bartonella
|
D001473;D001474;D002685;D004175
|
T204;T007;T015;T047
|
34,695,288 |
direct act antivir reduc risk tumour progress hepatocellular carcinoma curat treatment hepatocellular carcinoma hcc high recurr rate hcc sometim progress earli stage hcc barcelona clinic liver cancer bclc stage advanc stage hcc repeat recurr treatment hcc progress deterior qualiti life prognosi howev effect direct act antivir daa induc sustain virolog respons svr hcc progress remain uninvestig conduct retrospect cohort studi patient hepat c virus relat hcc bclc stage diagnos first time treat curat resect ablat use time vari method estim risk tumour progress defin progress bclc stage b liver relat death characterist repeat recurr overal patient enrol follow curat hcc treatment patient receiv daa therapi daa treat group wherea untreat group approxim recurr earli stage expect diseas free retreat record tumour progress observ second recurr multivari adjust time vari cox regress analysi show daa induc svr signific reduc risk tumour progress hazard ratio hr p liver relat death hr p annual incid hcc treatment tumour progress untreat daa treat group respect hr p daa induc svr signific reduc risk tumour progress liver relat death frequenc hcc treatment follow curat treatment hcc bclc stage
|
D006528;D019698;D008113
|
T191;T047
|
34,695,287 |
recent advanc small molecul base intracellular ph probe intracellular ph play import role mani biolog patholog process small molecul base ph probe found effect ph sens eas prepar high sensit quick respons mani advantag small perturb function target function adapt cellular compon specif local etc present review highlight flurri recent activ develop probe probe categor base type fluorophor use like quinolin coumarin bodipi rhodamin indolium naphthalimid etc analyt perform discuss
|
D005456;D053644
|
T130;T109
|
34,695,284 |
virucid efficaci antimicrobi surfac coat envelop bacteriophag antimicrobi coat use combin routin clean disinfect evalu effect reduc virus concentr stainless steel surfac
|
D000890;D001435
|
T121;T005
|
34,695,280 |
psycholog distress earli childhood risk adolesc spinal pain impact spinal pain sp includ neck back pain common often associ poor mental health reduc qualiti life adolesc contemporari understand sp favour biopsychosoci approach emerg evid suggest stronger influenc psycholog rather factor
|
D000079225;D011788
|
T048;T078
|
34,695,277 |
outcom clostridioid difficil infect inpati liver transplant popul chronic immunosuppress known caus clostridioid difficil present colon infect associ increas mortal morbid aim determin inpati outcom liver transplant patient clostridioid difficil infect cdi trend last year
|
D016360;D003015;D016031
|
T037;T007;T061;T047
|
34,695,276 |
identif character srb new allel wheat stem rust resist gene sr effect ug race group wheat stem black rust caus puccinia gramini f sp tritici pgt histor among devast global fungal diseas wheat recent occurr spread new virul race ug prompt global effort identifi isol effect stem rust resist sr gene report map base clone ug effect srtm gene diploid wheat triticum monococcum access pi encod typic coil coil nucleotid bind leucin rich repeat protein gene design srb new allel sr rare insert larg kb retrotransposon second intron biolist transform kb circular bacteri artifici chromosom plasmid carri srb suscept wheat varieti fielder suffici confer resist stem rust survey wheat genotyp srb present cultiv monococcum subsp monococcum access absent test tetraploid hexaploid wheat line develop diagnost molecular marker srb success introgress monococcum chromosom segment contain gene hexaploid wheat acceler deploy pyramid sr gene wheat breed programm srb valuabl compon gene pyramid transgen cassett combin differ resist gene control devast diseas
|
D001487;D060467;D014908
|
T040;T168;T004;T002
|
34,695,275 |
silk embol materi cathet direct endovascular drug deliveri embol cathet base minim invas procedur deliber occlud diseas blood vessel treatment purpos novel silk base embol materi sem develop optim provid tandem integr embol deliveri therapeut report natur silk process fibroin protein vari length combin charg nanoclay particl allow visibl inject use clinic cathet small diamet length cm sem load fluorochrom label bovin albumin nivolumab among use immunotherapi drug worldwid demonstr sustain releas profil vitro day porcin renal surviv model sem label albumin nivolumab success embol porcin arteri without recan lead deliveri albumin nivolumab interstiti space renal cortex mechanist shown tissu deliveri optim intern elast membran embol arteri disrupt sem potenti next generat multifunct embol agent achiev embol deliv wide rang therapeut treat vascular diseas includ tumor
|
D004621;D047011
|
T116;T061;T121;T123
|
34,695,274 |
cerebellar patholog disabl worsen relaps remit multipl sclerosi retrospect analysi combirx trial cerebellar damag valuabl predictor disabl particular progress multipl sclerosi clear could equal use predictor motor disabl worsen relaps remit phenotyp
|
D006233;D000068079;D009103;D020529
|
T047;T101
|
34,695,272 |
experi adolesc parent receiv adolesc genom screen result consider debat whether adolesc opportun learn genet inform adult onset diseas risk carrier status without clinic indic adolesc face increas opportun learn genet risk return secondari find clinic genom test direct consum genet test research opportun howev littl known perspect adolesc receiv genom screen result conduct separ qualit interview adolesc parent enrol research protocol decid genom screen result receiv adolesc condit inform gene goal interview explor impact adolesc learn genom result without clinic indic screen particip dyad four receiv posit result pathogeniclik pathogen plp variant autosom domin ad condit five receiv carrier result heterozyg plp variant autosom recess ar condit six receiv negat result interpret descript qualit approach use interview transcript code use guid develop studi team base theme emerg interview degre recal descript result action emot respons differ accord type result receiv howev particip satisfi decis learn result report last psycholog harm particip adapt genom inform even learn unexpect increas risk futur health problem find support posit whenev possibl perspect wish adolesc strong consid respect decis make process regard genet test
|
D000067108;D010290
|
T058;T099;T102
|
34,695,269 |
strong genotyp genotyp interact aphid defens symbiont parasitoid persist across differ biotic environ dynam coevolut host parasit influenc genet interact high specif interact outcom infect depend precis combin host parasit genotyp g g interact potenti maintain genet variat induc negat frequenc depend select import effect also rest whether interact consist across differ environ modifi environment variat g g e interact black bean aphid aphi faba resist parasitoid lysiphlebus fabarum larg determin possess herit bacteri endosymbiont hamiltonella defensa strong g g interact h defensa l fabarum key environment factor system host plant aphid feed expos genet ident aphid harbour three differ strain h defensa three asexu genotyp l fabarum measur parasit success three common host plant faba name vicia faba chenopodium album beta vulgari expect observ pervas g g interact h defensa l fabarum despit strong main effect host plant averag rate parasit interact alter signific host plant environ g g e interact symbiont confer specif resist thus like mediat coevolut faba l fabarum even play across divers host plant aphid
|
D001042;D014863
|
T204
|
34,695,267 |
incid elder abus east asian cultur background systemat review meta analysi elder abus ea critic social health econom issu worldwid date limit inform ea certain similar cultur specif subpopul especi east asia studi aim summar ea incid east asia systemat review meta analysi identifi variat heterogen incid estim
|
D004552
|
T048;T054
|
34,695,266 |
increas yield dri field molecular pathway grow potenti drought stress constitut one major constraint agricultur world devast effect expect increas follow year due climat chang concurr increas food demand steadili grow popul requir proport increas yield crop product past research aim increas plant resili sever drought stress howev often result stunt growth reduc yield favor condit moder drought nowaday drought toler research aim maintain plant growth yield drought condit overal recent deploy strategi engin drought toler lab classifi growth center strategi focus keep growth unaffect drought stress drought resili without growth penalti strategi main aim still boost drought resili limit side effect plant growth review put scope two strategi molecular player success engin generat drought toler plant abscis acid brassinosteroid cytokinin ethylen ros scaveng gene strigolacton aquaporin discuss pathway particip growth stress respons regul drought final present overview current insight futur perspect develop new strategi improv drought toler field
|
D013312
|
T046;T040;T039;T121;T032
|
34,695,265 |
spiderweb nanomechan reson via bayesian optim inspir natur guid machin learn ultrasensit detector fundament forc quantum network sensor mechan reson enabl next generat technolog oper room temperatur environ current silicon nitrid nanoreson stand lead microchip platform advanc allow mechan reson whose motion remark isol ambient thermal nois howev date human intuit remain drive forc behind design process inspir natur guid machin learn spiderweb nanomechan reson develop exhibit vibrat mode isol ambient thermal environ via novel torsion soft clamp mechan discov data driven optim algorithm bioinspir reson fabric experiment confirm new paradigm mechan qualiti factor billion room temperatur environ contrast state art reson mileston achiev compact design requir sub micromet lithograph featur complex phonon bandgap make signific easier cheaper manufactur larg scale result demonstr abil machin learn work tandem human intuit augment creativ possibl uncov new strategi comput nanotechnolog
|
D055617;D036103
|
T068;T170;T090
|
34,695,264 |
concord phylogeograph respons larg scale coastal disturb intertid macroalga epibiota major ecolog disturb event provid opportun assess multispeci respons upheav particular catastroph disturb region extirp habitat form speci potenti influenc genet divers larg number codistribut taxa howev due rariti disturb event ecolog timefram genet dynam multispeci recolon process remain littl understood use singl nucleotid polymorph snp data multipl coastal speci track dynam cocolon event respons ancient earthquak disturb southern new zealand specif use compar phylogeograph approach understand extent epifauna vari ecolog associ macroalg host share compar spatial tempor recolon pattern studi reveal concord disturb relat phylogeograph break two intertid macroalg speci along two associ epibiot speci chiton isopod contrast two codistribut speci one epibiot amphipod subtid macroalga show genet effect palaeoseism coastal uplift phylogeograph model select reveal similar post uplift recolon rout epibiot chiton isopod macroalg host addit codemograph analys support synchron popul expans four phylogeograph similar taxa find indic coastal paleoseism activ driven concord impact multipl codistribut speci concert recolon event probabl facilit macroalg raft result highlight high resolut compar genom data help reconstruct concert multispeci respons recent ecolog disturb
|
D012624
|
T204
|
34,695,260 |
natur variat zmcgt respons isoorientin accumul maiz silk maiz zea may l silk contain high level flavonoid wide use promot human health isoorientin natur c glycosid flavon abund maiz silk attract consider attent due potenti valu although differ class flavonoid well character plant gene involv biosynthesi isoorientin maiz larg unknown use target metabol profil isoorientin silk associ panel consist maiz inbr line identifi gene zmcgt genom wide associ analysi zmcgt protein character hydroxyflavanon c glycosyltransferas c glycosyl hydroxyflavanon form flavon c glycosid dehydr moreov zmcgt overexpress increas isoorientin level rna interfer mediat zmcgt knockdown decreas accumul isoorientin maiz silk two nucleotid polymorph ac ag led amino acid chang il eg respect identifi function polymorph respons natur variat isoorientin level summari identifi gene zmcgt play import role isoorientin biosynthesi provid insight genet basi natur variat isoorientin level maiz silk identifi favor cg allel zmcgt may use genet improv nutrit qualiti maiz
|
D014644
|
T070
|
34,695,258 |
compar transcriptom analysi winter yak plateau plain yak import sourc peopl live ecolog environ qinghai tibet plateau everi winter mani domest yak lose bodyweight dead cold food scarciti move plateau yak farm plain use approach reduc environment stress gain product studi measur growth slaughter beef qualiti trait everi month sequenc mrna express level muscl two group yak live plateau plain respect found signific differ p valu third day fourth day fifth day sixth day weight subpopul plateau plain identifi differ express gene deg includ known gene unknown gene use weight correl network analysi wgcna build co express network modul strong relat weight trait find highlight under way relat network yield new view gene express yak live plateau plain
|
D020869;D059467
|
T081;T063;T059;T086
|
34,695,256 |
invas aspergillosi relapsedrefractori acut myeloid leukaemia patient result seifem b survey patient relapsedrefractori acut myeloid leukaemia rr aml receiv salvag chemotherapi limit updat studi explor incid invas aspergillosi ia role antifung prophylaxi ap aim multicentr retrospect seifem b studi follow evalu current rate outcom provenprob ia assess efficaci ap larg real life seri patient rr aml submit salvag chemotherapi
|
D000935;D001228;D000072742;D015470
|
T195;T121;T191;T047
|
34,695,254 |
evalu experi individu person health risk identifi expand carrier screen expand carrier screen ec use identifi individu coupl risk children recess x link genet condit howev person health risk phr also identifi test limit data genet counsel regard phr ec perceiv individu use inform studi quantit survey individu identifi risk septemb march item survey includ valid genom outcom scale short form valid genet counsel satisfact scale origin question survey topic includ pre test knowledg possibl discov phr test satisfact pre test educ address potenti risk perceiv sever phr empower understand inform anxieti level relat phr perceiv genet counsel support satisfact telehealth total complet survey analyz use descript statist linear logist regress major particip satisfi extrem satisfi pre test educ n telehealth n howev particip awar possibl identifi phr ec prior test satisfi pre test educ compar awar addit lack prior awar phr associ lower empower score p high satisfi genet counsel like feel empow understand inform present p major individu use phr inform follow result appoint n result studi suggest receiv phr inform use posit influenc pre test educ genet counsel process
|
D005817;D017216
|
T058;T061;T091
|
34,695,253 |
system immun inflamm index predict clinic outcom patient type b aortic dissect undergo thorac endovascular repair system immun inflamm index sii report prognost abil various cardiovascular diseas howev studi type b aortic dissect tbad aim explor relat sii short term long term outcom tbad patient undergo thorac endovascular repair tevar
|
D057510
|
T061
|
34,695,252 |
biodegrad polym effect near infrar ii absorpt phototherm agent deep tumor therapi phototherm therapi hold great promis cancer treatment due effect tumor ablat minim invas herein new class biodegrad phototherm agent effect adsorpt near infrar nir nir ii window report deep tumor therapi demonstr deep seat ovarian cancer model phototherm therapi use nm irradi effect inhibit tumor progress prolong surviv span work provid new design phototherm agent toward effect therapi tumor
|
D009369;D011108
|
T122;T191;T104
|
34,695,251 |
effect site applic densiti uv protect efficaci sunscreen sun protect factor spf uva protect factor uvapf perform indic consum recogn uv protect cosmet sunscreen howev site applic densiti affect actual uv protect despit indic understand actual uv protect better reliabl manner need verifi applic densiti discuss photoprotect efficaci regard public health
|
D003358;D013473
|
T167;T073
|
34,695,249 |
advanc analyt method assess physic activ behavior use acceleromet time seri scope review physic activ pa complex human behavior impli multipl dimens need taken account order reveal complet pictur pa behavior profil individu scope review aim map advanc analyt method summari variabl hereinaft refer wearabl specif indic pa behavior wipab use assess pa behavior strength limit indic well potenti associ certain health relat factor also investig three databas medlin embas web scienc screen articl publish english januari april articl assess pa behavior gather object measur pa use tri axial acceleromet investig wipab select studi report wipab context pa monitor synthes present four summari tabl studi characterist detail wipab strength limit measur associ indic health relat factor total record identifi articl includ assess titl abstract full text thirteen wipab identifi classifi three differ categori specif focus activ intens distribut activ accumul tempor correl regular acceler signal five thirteen wipab identifi review use literatur far investig relationship pa behavior health may provid use addit inform convent pa variabl
|
D009043;D060145
|
T056;T170;T052;T066
|
34,695,247 |
modif enteromorpha prolifera dielectr barrier discharg plasma enhanc malachit green adsorpt dye kind visibl chemic sever deleteri effect human health ecolog environ work batch biosorpt experi carri various experiment condit ph valu agit time optim potenti enteromorpha prolifera remov malachit green mg dye aqueous solut algal biomass treat dielectr barrier discharg dbd helium min enhanc mg remov effici addit fourier transform infrar spectroscopi combin scan electron microscopi employ monitor chemic physic chang algal cell treat dbd studi illustr dbd may serv effect tool activ function group cell wall surfac dye bind even offer altern new techniqu improv adsorpt properti nativ biosorb remov toxic dye wastewat
|
D014874
|
T131
|
34,695,246 |
cephalopod inspir design photomechan modul display system demand fluoresc pattern cephalopod display variabl bodi colorpattern upon environment stimul via bioelectr control muscl contractionexpans skin chromatophor howev remain challeng produc artifici display analog exhibit revers rapid switch multipl expect luminesc pattern although system appeal mani practic use eg data encrypt inspir bioelectromechan display tactic cephalopod work conceptu new photomechan modul fluoresc system enabl demand display fluoresc pattern via cascad stimul mechan movement optic output conduct mechan present specif biomimet system compris customiz hollow display panel bottom tether phototherm respons fluoresc actuat nir light photomechan bend movement fluoresc actuat immedi cover hollow window display panel synchron manifest display fluoresc pattern owe desir time light power depend actuat behavior divers fluoresc patternsinform dynam revers display facil control singl remot nir signal bioinspir strategi univers promis fabric demand fluoresc display platform combin wide choic fluorophor remot control high spatialtempor precis especi singl input multipl output featur
|
D049830;D002856
|
T204;T025
|
34,695,245 |
chang total segment extracellular intracellular volum hypotens hemodialysi measur bioimped spectroscopi bioelectr imped analysi bia devic advoc guid volum manag hemodialysi hd patient hypothes understand dynam fluid shift differ bodi segment may provid addit insight prevent measur reduc risk intradialyt hypotens
|
D007022;D007676
|
T033;T047
|
34,695,244 |
unexpect post glacial colonis rout explain white colour barn owl tyto alba british isl climat fluctuat quaternari shape movement speci glacial refugia europ major speci follow one describ tradit postglaci recolon rout southern peninsula toward north like organ barn owl assum colon british isl cross doggerland land bridg connect britain northern europ howev dark rufous northern europ barn owl british isl conspicu white contrast could suggest select forc play island yet analysi known candid gene involv color found signatur select instead use whole genom sequenc speci distribut model found owl colonis british isl soon last glaciat direct white colour refugium iberian peninsula colonis northern europ would follow hitherto unknown post glacial colon rout isl westward path suitabl habitat submerg land bay biscay thus cross doggerland inherit white colour iberian founder maintain low gene flow mainland prevent import rufous allel thus contend neutral process probabl explain contrast white colour compar continent owl barn owl top predat expect futur research show unanticip rout use speci paleo communiti
|
D020305
|
T012
|
34,695,238 |
plasma glutathion prodrom parkinson diseas probabl decreas glutathion gsh level consid one earliest biochem chang parkinson diseas pd
|
D005978;D010300;D062706
|
T034;T121;T047;T123;T184;T116
|
34,695,237 |
homeophas adapt respons uva radiat pseudomona aeruginosa chang membran fatti acid composit induct desa desb express bacteria exposur chang environment condit alter membran fluiditi therebi affect essenti function cell physiolog adapt chang bacteria maintain appropri fluiditi vari composit fatti acid membran phospholipid phenomenon known homeophas adapt pseudomona aeruginosa respons achiev main two mechan fatti acid desatur faba fabb desa desb system studi analyz effect ultraviolet uva radiat major fraction solar uv radiat reach earth surfac homeophas process prototyp strain pao grown subleth uva dose dark profil membran fatti acid compar earli logarithm logarithm stationari growth phase logarithm growth phase observ growth subleth uva dose induc express desaturas encod gene desa desb increas proport unsatur fatti acid addit membran fluiditi could also increas suggest indic use indic paramet opposit effect observ stationari growth phase result demonstr relev role uva homeophas respons transcript level
|
D005227;D011550
|
T168;T109;T007;T123
|
34,695,236 |
chlamydia abortus omcb protein essenti adhes host cell chlamydia abortus c abortus one import zoonot pathogen caus number serious diseas adhes c abortus host cell first crucial step process infect outer membran protein omcb second abund outer membran protein shown import adhesin chlamydia trachomati chlamydia pneumonia present studi omcb gene c abortus clone express escherichia coli recombin omcb protein tag use prepar polyclon antibodi infect inhibit assay carri c abortus presenc recombin omcb show consider reduct infect use anti omcb serum infect inhibit assay result reduct infect anti omcb serum recombin omcb protein infect inhibit assay show omcb surfac expos protein function adhesin construct delet variant omcb motif infect inhibit assay show first xbbxbx motif c abortus omcb protein essenti bind host cell
|
D001425;D016993
|
T007;T116;T123
|
34,695,235 |
character cwlc autolysin role mother cell lysi bacillus thuringiensi subsp israelensi bacillus thuringiensi subsp israelensi bti proven effici control mosquito mani speci import vector human diseas larvicid action attribut paraspor crystal form sporul cell releas upon cell autolysi studi sporul specif cwlc gene encod n acetylmuramoyl l alanin amidas character bti strain bt cwlc cell wall hydrolas bti found contain murnac laa amidasec domain recombin cwlc protein abl digest bacillus cell wall delet cwlc gene delay bti mother cell lysi without impact veget growth insecticid efficaci transcript analys indic cwlc express late sporul stage control sigk two cell wall hydrolas gene cwlb cwle high express level bt also identifi like cwlc cwlb express control sigk contrast cwle found control sigma factor unlik two gene found plasmid encod
|
D001413;D001426;D009238
|
T007;T116;T126;T123
|
34,695,234 |
function genom abiot environment adapt lacertid lizard vertebr understand genom basi adapt differ abiot environ import context climat chang result short term environment fluctuat use function compar genom approach investig whether signatur genom adapt set environment paramet concentr specif subset gene function lacertid lizard vertebr first identifi gene signatur posit diversifi select transcriptom speci lacertid lizard demonstr involv physiolog morpholog adapt climat understand function similar gene previous predict candid function climat adapt compar vertebr speci perform meta analysi gene select obtain omic studi vertebr speci adapt differ abiot factor found vertebr gene set form tight connect interactom enrich previous predict function adapt climat larg part involv organism stress respons found much higher degre ident gene repeat select among differ anim group function similar post translat modif expect chanc clear function divis gene use ectotherm endotherm physiolog strategi total gene lacertida part network result highlight import role compar small set gene function environment adapt narrow set candid pathway marker use futur research adapt stress respons relat climat chang
|
D023281;D008116
|
T014;T091
|
34,695,233 |
lesson deprescrib nonessenti medic hold polici us nurs home height covid pandem larg nurs home chain implement polici temporarili hold potenti unnecessari medic describ rate held discontinu medic temporari hold polici potenti unnecessari nonessenti medic
|
D000086382;D000069340;D009735
|
T058;T073;T170;T047;T093;T067
|
34,695,232 |
comparison g g vagin misoprostol cervic ripen oper hysteroscopi random control trial compar g vagin misoprostol cervic ripen oper hysteroscopi
|
D016595;D010120
|
T039;T121;T109
|
34,695,231 |
structur allergen properti fatti acid bind protein shrimp litopenaeus vannamei shrimp litopenaeus vannamei import sourc food allergen allergen repertoir poor character cross reactiv crustacean mite report tropomyosin relev allergen involv aim studi investig structur immunolog properti recombin fatti acid bind protein fabp famili l vannamei lvfabp
|
D005512;D033561
|
T046;T204
|
34,695,229 |
sar cov reactiv antibodi detect sar cov vaccin hematopoiet stem cell transplant recipi prospect survey spanish hematopoiet stem cell transplant cell therapi group multicent prospect observ studi includ larg cohort n allogen allo hsct n autolog asct hematopoiet stem cell transplant n recipi monitor antibodi detect within week complet sever acut respiratori syndrom coronavirus sar cov vaccin februari juli patient n receiv mrna base vaccin recipi vaccin year transplant detect sar cov reactiv antibodi observ allo hsct asct recipi multivari analysi allo hsct recipi identifi lymphopenia ml odd ratio confid interv ci p activ graft versus host diseas gvhd ci p vaccin within first year transplant ci p associ lower antibodi detect wherea asct non hodgkin lymphoma nhl ci p activ corticosteroid therapi ci p associ lower detect rate report encourag rate sar cov reactiv antibodi detect sever immunocompromis patient lymphopenia gvhd time vaccin nhl corticosteroid therapi consid allo hsct asct respect identifi candid sar cov antibodi monitor
|
D018380
|
T061
|
34,695,228 |
adipos tissu insulin resist lipidom alter character factor non alcohol steatohepat preval non alcohol fatti liver diseas nafld general popul increas subject obes andor type diabet simpl steatosi nafl develop sever form non alcohol steatohepat nash cirrhosi hepatocellular carcinoma lead death
|
D007333;D000081362
|
T046;T109;T091
|
34,695,227 |
longitudin sar cov seropreval portug antibodi mainten month infect covid pandem portug experienc three distinct sar cov infect wave previous document preval sar cov immun measur specif antibodi septemb month initi moder wave show seropreval chang month later second week march short follow third wave one sever world month follow start vaccin campaign longitudin epidemiolog studi conduct stratifi quota sampl portugues popul serolog test perform includ elisa determin antibodi class titer proport seroposit septemb rose sharpli ci march import circul igg iga antibodi level stabl month initi determin year initi infect indic long last infect immun sar cov moreov vaccin peopl higher igg level week post vaccin compar previous infect peopl time post infect
|
D000086382;D000087124
|
T059;T047;T067
|
34,695,226 |
associ healthi lifestyl caus mortal accord medic burden healthi lifestyl associ reduc caus mortal known whether associ persist individu high medic burden examin associ healthi lifestyl behavior caus mortal across differ degre polypharmaci
|
D006304;D008019
|
T054;T080;T047
|
34,695,225 |
publish popul pharmacokinet model busulfan use individu dose chines pediatr patient undergo hematopoiet stem cell transplant extern evalu busulfan bifunct alkyl agent wide use hematopoiet stem cell transplant hsct combin chemotherapeut drug popul pharmacokinet poppk model busulfan chines pediatr patient system extern evalu publish poppk model conduct chines pediatr patient undergo hsct forti pediatr patient enrol studi total blood concentr relat predict error pe median pe median absolut pe percentag pe within calcul predict base diagnost simul base diagnost conduct predict variabl correct visual predict check normal predict distribut error relat individu predict error calcul use bayesian forecast concentr point compart open linear poppk model built su jin rhee et al model h incorpor patient bodi surfac area age dose day aspart aminotransferas signific covari prefer predict poppk model predict base diagnost median pe percentag pe within percentag pe within model h respect normal predict distribut error model h show follow normal distribut base bayesian forecast model h show good predict perform thus model h appropri model use clinic individu dosag adjust chines pediatr hsct patient
|
D002066;D018380
|
T131;T121;T061;T109
|
34,695,224 |
deep sequenc across multipl host speci test pine endophyt specif foliar fungal endophyt vari distribut across landscap plant host taxa indic special ecolog host specif adapt account special howev depend taxonom breadth geograph rang host plant includ studi broad region scale studi deep sampl divers potenti host speci still remain relat rare becom increas possibl high throughput sequenc
|
D060026;D028223
|
T002;T004
|
34,695,223 |
assess biomark pediatr atop dermat tape strip skin biopsi cytokin profil atop dermat ad depend age ethnic diseas sever studi examin biomark children ad collect tape strip skin biopsi examin whether level differ filaggrin genotyp diseas sever food allergi
|
D003876
|
T047
|
34,695,222 |
tea crude extract effect inactiv sever acut respiratori syndrom coronavirus well known black green tea extract particular polyphenol antimicrobi activ various pathogen microb includ virus howev limit data antivir activ sever acut respiratori syndrom coronavirus sar cov emerg rapid china late respons coronavirus diseas covid pandem global studi compound three extract obtain black green tea found three tea extract show signific antivir activ sar cov wherebi viral titr decreas log tcid per ml mg ml black tea extract two fold dilut tea bag infus obtain black tea incub c howev concentr black green tea extract equal adjust g ml green tea extract show antivir activ sar cov simpl high respect beverag may cheap wide accept mean reduc sar cov viral burden mouth upper gastrointestin respiratori tract develop well develop countri
|
D000086382;D028241;D002392
|
T121;T002;T047;T067;T109
|
34,695,221 |
myocardi infarct peripher arteri diseas treatment pattern long term outcom men women result swedish nationwid studi differ comorbid pharmacotherapi cardiovascular cv outcom mortal myocardi infarct mi patient peripher arteri diseas pad patient well document
|
D009203;D058729
|
T047
|
34,695,220 |
associ short term exposur air pollut myocardi infarct without obstruct coronari arteri diseas air pollut includ particul matter aerodynam diamet pm increas risk acut myocardi infarct howev whether short term exposur pm trigger onset myocardi infarct nonobstruct coronari arteri compar myocardi infarct coronari arteri diseas elucid studi aim estim associ short term exposur pm admiss acut myocardi infarct myocardi infarct coronari arteri diseas myocardi infarct nonobstruct coronari arteri
|
D000393;D000397;D003324;D009203
|
T131;T080;T069;T047
|
34,695,219 |
extracellular vesicl speci differenti affect endotheli cell function differenti respond exercis train patient chronic coronari syndrom extracellular vesicl releas upon cellular activ mediat inter cellular communic individu speci extracellular vesicl might diverg role vascular homeostasi may show differ respons therapi exercis train
|
D000067128;D000072696
|
T056;T026;T061
|
34,695,218 |
long term cumul blood pressur young adult incid heart failur coronari heart diseas stroke cardiovascular diseas cardia studi cumul blood pressur bp measur incorpor sever durat bp exposur prognost signific cumul bp young adult cardiovascular diseas cvds comparison bp sever alon howev unclear
|
D002318;D003327;D006333;D006973;D020521
|
T046;T047
|
34,695,217 |
impact smoke cardiovascular outcom patient stabl coronari arteri diseas smoke major prevent risk factor cardiovascular diseas mortal howev smoker paradox suggest associ better surviv acut myocardi infarct aim investig impact smoke mortal cardiovascular outcom patient stabl coronari arteri diseas
|
D003324;D009203;D062645
|
T061;T047
|
34,695,216 |
impact environment pollut weather chang incid st elev myocardi infarct environment pollut weather chang unfavor impact cardiovascular diseas howev limit research focus st elev myocardi infarct stemi sever yet distinct form acut coronari syndrom
|
D000393;D000397;D000072657
|
T131;T080;T069;T047
|
34,695,213 |
hypotherm fibrillatori arrest coronari arteri bypass graft man calcifi aorta ventricular fibril year old man undergo coronari arteri bypass graft aortic calcif prohibit aortic cross clamp ventricular fibril develop surgeri institut hypotherm fibrillatori arrest avoid aortic cross clamp addit patient case discuss advantag disadvantag use hypotherm fibrillatori arrest cardiac surgeri
|
D001018;D014693
|
T047
|
34,695,211 |
connectom enough still need understand brain drosophila understand structur oper nervous system subject research well centuri near term opportun quest understand brain model speci fruit fli drosophila melanogast entic target given relat small size rough neuron coupl behavior rich brain support wide varieti techniqu avail studi brain behavior clear within year possess connectom melanogast electron microscopi level descript neuron chemic synapt connect given soon alreadi know research current underway need know enabl us understand fli brain item data need obtain collat organ order build integr model brain melanogast
|
D063132
|
T017;T091
|
34,695,208 |
sika deer cervus nippon dead end host giant liver fluke fascioloid magna bassi ward fascioloid magna although north american origin well establish central europ expand geograph rang expos new potenti final host includ nativ natur speci base contribut propag transmiss f magna final host group three type includ dead end host compris speci fluke reach liver rare matur produc egg excret sika deer cervus nippon classifi dead end host quot literatur without robust substanti investig occurr f magna among sympatr wild ungul recent establish focus parasit germani nine sika deer found infect seven f magna liver six fluke posit sika deer fascioloid egg fece fluke recov pair fibrous capsul associ low fluke burden gross patholog liver general mild presenc matur fluke fibrous capsul pass ova fece demonstr sika deer suitabl definit host f magna epidemiolog signific implic transmiss fluke
|
D003670;D005210;D005212;D014200;D014201
|
T204;T015;T047
|
34,695,206 |
ornithodoro turicata dug feral hog real counti texa usa potenti introduct african swine fever virus asfv us research evalu rout potenti transmiss establish sylvat cycl help document vector host associ relat asfv transmiss find turicata feral hog real counti texa report
|
D000357;D000358;D026861;D013553
|
T204;T005;T047
|
34,695,205 |
high voltag injuri contact overhead line case report two young girl high voltag burn injuri rare pediatr age group lead devast sever sequela present case two young girl suffer high voltag burn injuri due direct contact overhead power line patient came difficult psychosoci background injuri result sever long term consequ function deficit
|
D002056
|
T037
|
34,695,202 |
usag negat pressur wound therapi pseudoepitheliomat hyperplasia secondari burn injuri case seri pseudoepitheliomat hyperplasia peh reactiv epitheli prolifer secondari wide rang stimuli includ traumat injuri inflamm infect tumor skin peh secondari burn injuri rare report report three case peh patient burn injuri three case confirm exist bacteri infect case second third degre burn three patient treat negat pressur wound therapi wound debrid tangenti excis wound heal without split thick skin graft recurr
|
D002056;D054843
|
T037;T061;T074
|
34,695,201 |
comparison chronic wast diseas detect method procedur implic free rang white tail deer odocoileus virginianus surveil manag throughout north america chronic wast diseas cwd emerg perhap greatest threat wild cervid popul includ white tail deer wtd odocoileus virginianus white tail deer sought big game speci across north america popul various subspeci near canadian provinc contigu us mexico document cwd case dramat increas across wtd rang sinc mid includ minnesota us cwd surveil free rang wtd cervid popul main depend upon immunodetect method immunohistochemistri enzym link immunosorb assay elisa medial retropharyng lymph node obex recent technolog center prion protein amplif method detect shown promis sensit rapid cwd diagnost tool use blind sampl test efficaci real time quak induc convers rt quic comparison elisa screen tissu collect wtd southeastern minnesota cwd routin detect sinc result support previous find rt quic sensit tool cwd detect current antibodi base method addit cwd test protocol includ multipl lymphoid tissu eg medial retropharyng lymph node parotid lymph node palatin tonsil per anim effect identifi greater number cwd detect wtd popul singl sampl type eg medial retropharyng lymph node result show variabl cwd pathogenesi sampl protocol test platform must consid effect detect manag cwd throughout north america
|
D003670;D034081
|
T015;T047
|
34,695,200 |
physiolog respons wean piglet two transport durat observ canadian commerci set observ studi describ impact transport durat wean piglet welfar limit current canadian transport regul heavili inform studi involv market hog due physiolog differ wean piglet market hog addit data respons transport need age specif evid base recommend cohort studi conduct describ compar mortal injuri weight chang hematolog biochem chang hydrat muscl injuri stress respons observ wean piglet undergo short durat sd h commerci summertim transport event data collect transport piglet occur morn day transport arriv approxim h arriv nurseri barn low mortal occur transport event associ observ transport durat odd death transport p incid lame low focal piglet score lame case identifi mild sever lesion ear skin preval injuri type transport may relat mix aggress associ wean rather transport alon ld piglet weigh kg less sd piglet p differ group weight observ p hematolog biochem differ present group ld piglet increas hematocrit level compar sd piglet p suggest increas bodi water loss sd piglet show greater level muscl injuri compar ld piglet includ elev aspart aminotransferas p creatin kinas p howev paramet within normal refer rang piglet age group indic physiolog stress respons includ cortisol neutrophil lymphocyt ratio elev sd piglet compar ld piglet p p respect result studi demonstr short long transport durat result detect physiolog chang wean piglet overal impact durat piglet welfar explor analyz behavior time budget transport
|
D006854;D013312
|
T046;T040;T039;T121;T125;T032;T109
|
34,695,199 |
whole genom landscap adult cell leukemialymphoma adult cell leukemialymphoma atl aggress neoplasm immunophenotyp resembl regulatori cell associ human cell leukemia virus type perform whole genom sequenc wgs atl case reveal overarch landscap genet alter atl discov frequent loss function alter preferenti target cic long isoform overlook previous exom centric studi various cancer type long short isoform specif inactiv cic select increas cdcdfoxp cell vivo also found recurr truncat rel induc transcript upregul generat gain function protein import rel truncat also common diffus larg b cell lymphoma especi germin center b cell like subtyp non code genom identifi recurr mutat regulatori element particular splice site sever driver gene addit character differ mutat process oper cluster hypermut site within outsid immunoglobulint cell receptor gene identifi mutat enrich bind site host viral transcript factor suggest activ atl combin analys code noncod mutat structur variat copi number alter discov recurr alter driver gene includ novel one final atl case classifi molecular group distinct clinic genet characterist base driver alter profil find help improv diagnost therapeut strategi atl also provid insight cell biolog implic genom wide cancer driver discoveri
|
D015972;D009154
|
T045
|
34,695,197 |
morca psl mutant mice develop peripher central neuropathi associ neuron dna damag apoptosi microrchidia morc famili cw type zinc finger morc gene relat dna repair adipogenesi epigenet silenc via human silenc hub hush complex morc missens mutat known caus peripher neuropathi charcot mari tooth diseas type z cmtz howev report peripher central neuropathi patient diseas co categor development delay impair growth dysmorph faci axon neuropathi digfan etiolog morc mutat mediat neuropathi remain uncertain establish analyz morca psl mutant mice morca psl mice display clinic symptom expect human cmtz patient axon neuropathi skelet muscl weak notabl observ sever central neuropathi cerebella ataxia cognit disord motor neuron degener spinal cord seem evid digfan morca psl mice exhibit accumul dna damag neuron cell follow pcytochrom ccaspas caspas mediat apoptosi studi present new mous model cmtz digfan morca psl mutat suggest neuron apoptosi possibl target therapeut approach morc missens mutat articl associ first person interview first author paper
|
D017209;D004249
|
T116;T049;T043;T123
|
34,695,196 |
effect azaperon induct time etorphin immobil white rhinocero ceratotherium simum describ induct time six white rhinocero ceratotherium simum receiv etorphin intramuscular im etorphin plus azaperon im median induct time reduc min etorphin alon min azaperon howev differ immobil qualiti treatment
|
D001376;D005048
|
T121;T109
|
34,695,195 |
plcg requir aml eto leukemia stem cell self renew effort identifi novel drug target fusion oncogen induc acut myeloid leukemia aml perform high resolut proteom analysi aml eto ae driven aml uncov deregul phospholipas c plc signal identifi plcgamma plcg specif target ae fusion protein induc ae bind intergen regulatori dna element genet inactiv plcg murin human aml inhibit aml eto depend self renew program leukem prolifer leukemia mainten vivo contrast plcg dispens normal hematopoiet stem progenitor cell function find extend confirm pharmacolog perturb ca signal aml eto aml cell indic plcg pathway pose import therapeut target aml eto leukem stem cell
|
D015973
|
T045
|
34,695,191 |
technic contribut use continu record video monitor mainten pain behavior piglet surgic castrat valid six continu time sampl period behavior score castrat pain procedur routin perform piglet specif period relat castrat time sampl rule use wide quantifi deviat piglet behavior associ castrat rather assess behavior entir trial period howev limit work evalu time sampl record rule quantifi behavior chang piglet undergo castrat therefor object studi valid accuraci six continu time sampl period min quantifi piglet behavior post castrat compar full min observ period sixteen yorkshir landrac x duroc piglet surgic castrat data collect use continu observ record rule individu male piglet per litter min post castrat min continu behavior data set subdivid six data subset defin continu time sampl period min data continu time sampl period full period data analyz use general linear mix model linear regress analysi general linear mix model min continu time sampl period differ p compar full observ period data behavior linear regress analysi affili interact sit walk huddl prostrat scratch spasm trembl behavior met pairwis comparison accuraci criteria coeffici determin r intercept differ p slope differ p min continu time sampl period compar full observ period result studi suggest min continu time sampl period would necessari accur investig piglet behavior acut pain sensit time post castrat consid mainten pain associ behavior
|
D001522;D009919
|
T061;T053
|
34,695,188 |
pre exposur prophylaxi prep australia challeng face sexual health promot pre exposur prophylaxi prep hiv refer daili use antiretrovir medic hiv uninfect person block potenti hiv infect evid show use prep increas use safer sex practic condom decreas may lead increas sexual transmit infect stis studi aim explor whether prep caus challeng organ undertak sexual health promot activ australia depth semi structur interview conduct particip male femal purpos sampl rang hiv advocaci health promot set includ public fund hivaid council organ repres peopl live hivaid guid exploratori induct approach interview analyz use themat analysi three theme construct data analysi first organ differ jurisdict came support prep differ way influenc way organ engag prep messag dissemin communiti second organ face barrier promot prep signific overcom decad hiv prevent campaign focus barrier method third social benefit prep shift onus prevent hiv transmiss hiv posit hiv negat peopl prep high effect biomed intervent reduc hiv transmiss futur challeng includ design campaign risk hiv transmiss outsid msm communiti
|
D015658;D065129;D000072339
|
T061;T047;T098
|
34,695,187 |
synchron epidem growth imposs select contain contain aim prevent epidem stage communiti spread altogeth mitig aim mere flatten curv wide rang outbreak constitut two qualit differ approach combat epidem non pharmaceut intervent studi simpl model epidem dynam separ popul two group name low risk group high risk group differ strategi pursu due synchron effect find maintain slower epidem growth behaviour high risk group unstabl finit coupl two group precis densiti infect individu two group qualit evolv similar apart small time delay overal scale factor quantifi coupl group henc select contain epidem target high risk group practic imposs whenev surround societi implement mitig communiti spread relat general find ongo covid pandem
|
D000086382;D058873
|
T047;T067
|
34,695,184 |
mix nasopharyng myiasi bot blowfli roe deer capreolus capreolus mix nasopharyng infest larva cephenemyia stimul diptera oestrida lucilia caesar diptera calliphorida detect roe deer capreolus capreolus kill car collis lugo spain juli articl stress import correct identifi larva myiasi case
|
D003670;D004175;D009198
|
T204;T015;T047
|
34,695,176 |
two novel high risk adult b cell acut lymphoblast leukemia subtyp high express cdx idh mutat genet basi leukemogenesi adult b cell acut lymphoblast leukemia b larg unclear clinic outcom remain unsatisfactori studi aim advanc understand biolog characterist improv diseas stratif identifi molecular target adult b adolesc young adult aya year old n adult year old n philadelphia chromosom negat ph b includ studi integr transcriptom genet analys use classifi cohort defin subtyp case includ rna sequenc analysi classifi subtyp znf subtyp preval novel subtyp cdx high idh mut identifi among case assign establish subtyp cdx high subtyp character high express cdx recurr gain chromosom q idh mut subtyp defin idh rc idh rq mutat specif transcript high methyl profil subtyp show poor prognosi consid inferior prognost factor independ clinic paramet comparison previous report pediatr b cohort n show frequenc subtyp signific higher ayaadult children delin genet transcriptom landscap adult b identifi novel subtyp predict poor diseas outcom find highlight age depend distribut subtyp partial account prognost differ adult pediatr b
|
D054198
|
T191
|
34,695,175 |
gem scalabl flexibl gene environ interact analysi million sampl gene environ interact gei studi general framework use identifi genet variant modifi effect environment physiolog lifestyl treatment effect complex trait moreov account gei enhanc understand genet architectur complex diseas trait howev common use statist softwar program gei studi either applic test certain type gei hypothes optim use larg sampl
|
D059647;D055106
|
T063;T045
|
34,695,167 |
new paradigm leprosi diagnosi base host gene express transcript profil power tool investig detect human diseas studi use bulk rna sequenc rna seq compar transcriptom skin lesion leprosi patient control affect dermal condit granuloma annular confound paucibacillari leprosi identifi five gene capabl accur distinguish multibacillari paucibacillari leprosi skin condit indoleamin dioxygenas ido express alon high discriminatori follow tlr blk cd slamf wherea hsst cdlg mrna separ multi paucibacillari leprosi final main differenti express gene deg enrich pathway conclud paucibacillari diseas character epithelioid transform granuloma format exacerb cellular immun respons multibacillari leprosi featur epitheli mesenchym transit phagocyt lipid biogenesi pattern skin find help catalyz develop better diagnost tool potenti host base therapeut intervent final data may help elucid host pathogen interplay drive diseas clinic manifest
|
D059467
|
T086;T081
|
34,695,165 |
evalu sourc technic variabl mechano node pore sens pipelin effect reproduc singl cell mechan phenotyp cellular mechan properti reveal physiolog relev characterist mani cell type sever group develop microfluid base platform perform high throughput singl cell mechan test howev prior work perform limit character platform technic variabl reproduc evalu repeat perform mechano node pore sens singl cell mechan phenotyp platform develop research group measur degre devic devic variabl semi manual data process affect platform measur singl cell mechan properti demonstr high repeat across entir technolog pipelin even novic user compar result ident mechano node pore sens experi perform research two differ laboratori differ analyt instrument demonstr mechan test result two locat agreement find quantifi expect technic variabl mechano node pore sens even minim experienc hand import find repeat perform measur fulli suffici interpret biolog relev singl cell mechan measur high confid
|
D010641
|
T032
|
34,695,161 |
preval suicid behavior associ factor among wive polygami marriag live gedeo zone southern ethiopia polygami trend marriag character two wive husband time low middl incom countri includ ethiopia polygami signific negat effect social econom physic mental well women therefor studi aim assess preval associ factor suicid behavior among wive polygami marriag live gedeo zone southern ethiopia
|
D008603;D059020
|
T041;T033
|
34,695,160 |
memori medicin plant remain ancient modern environ suggest evolv adapted adapt memori propens human memori easili store retriev import inform deal challeng relat pleistocen recent evid show human multiregion evolut across african contin includ rainforest decidu forest howev littl evid regard implic origin relev recur challeng environ surviv process advantag memori studi conduct experi volunt analyz whether adapt memori oper retriev import inform solv challeng use medicin plant treat diseas ancestr environ savanna rainforest decidu forest compar modern environ desert tundra conifer forest urban area use simul surviv environ ask volunt per simul scenario imagin sick one environ need find medicin plant treat diseas volunt rate relev word solv challeng follow surpris memori test result show ancestr prioriti recal relev inform ancestr modern environ show similar recal relev inform suggest evolv cognit apparatus allow human be surviv creat surviv strategi face challeng impos various environ believ possibl human mind oper flexibl cognit mechan flexibl reflect exampl differ environ first hominid inhabit differ danger situat face
|
D000223;D011939;D010946;D013534
|
T052;T055;T002;T041
|
34,695,159 |
accuraci kinovea softwar estim bodi segment movement fall captur standard video effect fall direct camera perspect video calibr techniqu fall major caus unintent injuri understand movement bodi fall import design fall prevent manag strategi includ exercis program mobil aid fall detector protect gear safer environ video footag real life fall increas avail may use digit softwar extract kinemat featur fall examin valid approach conduct laboratori fall experi compar linear angular posit veloc measur motion captur estim kinovea digit softwar base standard surveil video hz x pixel also examin kinovea accuraci depend fall direct camera angl filter cut frequenc calibr techniqu camera orient perpendicular plane fall degre kinovea posit data filter hz video calibr use grid mean root mean squar error signal amplitud ms vertic posit veloc ms horizont posit veloc error angular measur averag fold higher sideway forward backward fall due plane movement knee elbow error horizont veloc fold higher degre camera angl fold higher calibr use particip height instead grid compar hz filter hz caus veloc error increas fold result demonstr kinovea appli hz video measur linear posit veloc within accuraci lower accuraci observ angular kinemat upper lower limb sideway fall horizont measur degre camera height base calibr
|
D000058;D012984
|
T037;T170;T090;T073
|
34,695,158 |
estim health impact digit last mile logist manag inform system lmis ethiopia tanzania mozambiqu live save tool list model analysi digit health becom wide recogn approach address rang health need includ advanc univers health coverag achiev sustain develop goal present limit evid impact digit intervent health outcom grow bodi peer review evid digit last mile electron logist manag inform system lmis present opportun estim health impact
|
D008331;D008962
|
T170;T062;T073
|
34,695,157 |
diseas associ variant gap junction beta protein gjb deaf popul southern punjab pakistan hear impair hi high heterogen genet disord classifi nonsyndrom without clinic manifest syndrom combin clinic present form variat gjb gene lead caus autosom recess nonsyndrom hear loss arnshl sever popul worldwid studi carri investig preval gjb variat sever profound hear impair famili southern punjab pakistan ten famili segreg arnshl recruit differ area region sanger sequenc gjb code region carri two ten famili nm c g p trp nm cdel p gludel homozyg variant identifi caus hear loss studi show gjb relat hear loss account least case sever profound hear loss southern punjab popul pakistan
|
D020022;D009154
|
T045;T032
|
34,695,156 |
sar cov infect central north carolina protocol popul base longitudin cohort studi preliminari particip result public health surveil system like underestim true preval incid sar cov infect due limit access test high proport subclin infect communiti base set ongo prospect observ studi aim generat accur estim preval incid risk factor sar cov infect among resid central north carolina counti cohort collect survey data nasal swab everi two week venous blood specimen everi month nasal swab test presenc sar cov virus evid activ infect serum specimen sar cov specif antibodi evid prior infect june enrol total particip counti estim total resid anticip studi durat least month pend evolut pandem studi data share month basi north carolina state health author futur analys aim compar studi data state wide metric time overal use probabl base sampl design well character cohort enabl collect critic data use plan polici decis north carolina may inform state similar demograph characterist
|
D011159
|
T062
|
34,695,155 |
brain deriv neurotroph factor promot immun reconstitut follow radiat injuri via activ bone marrow mesenchym stem cell brain deriv neurotroph factor bdnf member nerv growth factor famili extens studi role neural develop long term memori brain injuri neurodegen diseas bdnf signal tropomyosin receptor kinas b trkb stimul neuron cell surviv reason small molecul trkb agonist pre clinic develo treatment rang neurodegen diseas injuri laboratori recent report bdnf secret pro regen endotheli progenitor cell epc support hematopoiet reconstitut follow total bodi irradi tbi report bdnf trkb signal play novel regen role bone marrow thymic regener follow radiat injuri exogen administr bdnf trkb agonist dihydroxyflavon dhf follow myelosuppress radiat injuri promot faster recoveri matur blood cell hematopoiet stem cell capabl multi lineag reconstitut bdnf promot hematopoiet regener via activ pdgfr bone marrow mesenchym stem cell mscs increas secret hematopoiet cytokin interleukin il leukemia inhibitori factor lif respons trkb activ data suggest pharmacolog activ bdnf pathway either bdnf dhf may benefici treatment radiat chemotherapi induc myelosuppress
|
D000074243
|
T040
|
34,695,154 |
singl nucleotid polymorph copi number variat trypanosoma brucei repeat tbr sequenc use enhanc amplif genotyp trypanozoon strain trypanosoma brucei repeat tbr tandem repeat sequenc present trypanozoon minichromosom report tbr sequenc homogen previous believ blast analysi avail brucei genom reveal various tbr sequenc bp bp length sort two tbr group base key singl nucleotid polymorph convent quantit pcr primer match consensus sequenc target either tbr group show substanti copi number variat tbr repertoir within collect trypanozoon strain develop qtbr novel pcr consist three primer two probe simultan amplifi target sequenc two tbr group one singl qpcr reaction dual probe setup offer increas analyt sensit molecular detect trypanozoon taxa particular tb gambiens evansi compar exist tbr pcrs combin qtbr rdna amplif intern standard relat copi number tbr target sequenc calcul plot allow classif strain tbr genotyp associ east west central africa thus qtbr take advantag singl nucleotid polymorph copi number variat tbr sequenc enhanc amplif genotyp trypanozoon strain make promis tool preval studi african trypanosomiasi human anim
|
D056915;D020641;D012091
|
T086;T028;T123;T045;T114
|
34,695,152 |
autom genotyp microsatellit loci fece high throughput sequenc ecolog conserv genet studi often use noninvas sampl especi elus endang speci microsatellit general short length amplifi low qualiti sampl fece microsatellit high polymorph marker enough reliabl individu identif kinship determin popul character howev genotyp process fece expens time consum given next generat sequenc ngs recent softwar develop autom microsatellit genotyp ngs data may possibl softwar packag infer genotyp direct sequenc read increas throughput evalu perform four softwar packag genotyp microsatellit loci iberian wolf cani lupus fece use ngs initi combin marker singl multiplex reaction first time includ final analys megasat softwar provid genotyp fewer error coverag x provid littl addit inform relat high number pcr replic necessari obtain high qualiti genotyp high unoptim multiplex reaction replic loci analyz could reduc optim use new bioinformat tool next generat sequenc data genotyp high inform marker may increas throughput reason cost smaller amount laboratori work thus high throughput sequenc approach could facilit use microsatellit fecal dna address ecolog conserv question
|
D005243;D005838;D018895
|
T032;T114;T031;T123
|
34,695,151 |
search mean associ cost prosoci studi mean life larg center relationship person well focus mean relat enhanc well other receiv less research attent although search mean may impli lower person well find mean seeker motiv perform cost prosoci action sake other well given perceiv meaning behavior studi n show mean seek correl motiv engag rang cost prosoci behavior mean seek shown distinct pursu happi relationship cost prosoci studi share stronger associ high cost low cost prosoci studi studi n pre regist show search mean relat cost prosoci behavior recent past studi cross section pattern find suggest seek mean rather happi may play import role motiv altruist tendenc
|
D006240;D011788;D012649;D012919
|
T041;T054;T078
|
34,695,150 |
develop logic model chang determin parent nurtur first day mix method studi protocol parent play key role provid nurtur nurtur care child first day import optim child develop various factor found influenc parent contribut factor toward parent nurtur within first day yet known south african context paper describ protocol project aim develop logic model chang determin parent nurtur first day south african context
|
D002657;D010287;D012919;D012944
|
T040;T054;T039
|
34,695,146 |
stomata classif detect system microscop imag maiz cultivar plant stomata essenti structur pore control exchang gase plant leav atmospher also influenc plant adapt climat photosynthesi transpir stream mani work literatur aim better understand structur role evolut process behavior plant although stomata studi dicot speci advanc consider past year even much knowledg stomata cereal grass due high morpholog variat stomata trait intra inter speci detect classifi stomata automat becom challeng reason work propos new system automat stomata classif detect microscop imag maiz cultivar base transfer learn strategi differ deep convolut neural netwok dcnn perform experi show system achiev approxim accuraci identifi stomata region use classifi base deep learn featur figur near perfect classif system stomata respons sever plant function work repres import advanc maiz research provid accur system replac current manual task categor pore microscop imag furthermor system also refer studi use imag differ cereal grass
|
D010788;D018521;D018526
|
T040;T070;T039;T044
|
34,695,145 |
cfd studi water product matur heavi oil field horizont well excess water product matur heavi oil field caus increment cost energi consumpt ineffici understand multiphas flow near wellbor altern improv product effici therefor studi conduct seri numer experi base full set navier stoke equat simul multiphas flow porous media heavi oil product horizont well solut given advanc mathemat formul led descript movement fluid near wellbor unpreced detail sensit analysi conduct differ rock fluid properti permeabl oil viscos assum homogen porous media influenc paramet predict breakthrough time aquif movement sever water product notic final numer model verifi field data use two approach first one conduct histori match assum homogen rock properti contrast second one use heterogen rock properti measur well log achiev lower deviat field data homogen numer experi show breakthrough occur heel subsequ crestat along horizont well moreov advers mobil ratio excess water product tend happen water con heel inflow area less total inflow area complet liner differ aquif movement dynam found heterogen case like breakthrough multipl locat along horizont well final critic hydraul data well pressur veloc profil obtain could use improv product effici numer model present studi propos altern conduct subsurfac model well design
|
D061329;D014867
|
T073;T197;T121;T068;T070
|
34,695,143 |
hollow tree super direct scalabl approach featur import boost tree model current limit methodolog use throughout machin learn investig featur import boost tree model prevent effect scale dataset larg number featur particular one investig magnitud direct various featur classif posit negat class manuscript present novel methodolog hollow tree super hot design resolv visual featur import boost tree model involv larg number featur methodolog allow accur investig direct magnitud various featur classif incorpor cross valid improv accuraci valid determin featur import
|
D000465;D016208;D000069550;D015233
|
T081;T170;T066
|
34,695,142 |
socio econom demograph pattern mental health complaint among employ adult estonia mental health problem follow distinct socio econom gradient contribut health inequ studi aim analys socio econom demograph factor self report mental health complaint stress depress overtired suicid thought among employ adult popul estonia
|
D003710;D012959;D059020
|
T081;T080;T033;T062;T097;T082;T170;T102;T090;T098;T078
|
34,695,141 |
epidemiolog nosema spp effect indoor outdoor winter honey bee coloni popul surviv canadian prairi epidemiolog nosema spp honey bee api mellifera may affect winter condit cold temperatur differ winter method indoor outdoor provid vari level temperatur stress defec flight opportun across canadian prairi includ alberta length sever winter vari among geograph locat studi investig season pattern nosema abund two alberta locat use indoor outdoor winter method impact bee popul surviv commerci viabil studi found n cerana distinct season pattern alberta high spore abund spring declin low level summer fall result show fall nosema monitor might best indic treatment need futur coloni health outcom clear pattern differ n cerana abund locat winter method howev winter method affect surviv coloni winter indoor lower mortal rapid spring popul build outdoor winter coloni result suggest exist nosema threshold reinvestig winter method mind provid favor outcom beekeep averag nosema abund spring signific predictor end studi winter coloni mortal highlight import spring nosema monitor treatment
|
D012621;D013696
|
T079;T081
|
34,695,139 |
accuraci diagnost indic coeliac diseas systemat review meta analysi preval coeliac diseas cd around diagnosi challeng vari present non specif symptom sign studi aim identifi diagnost indic may help identifi patient higher risk cd test warrant
|
D002446
|
T047
|
34,695,137 |
express profil tumour suppressor protein p regul mdm cohort breast cancer patient tertiari hospit ghana inactiv mutat tumour suppressor gene p regul mous doubl minut mdm commonest event breast cancer alter gene usual express abnorm high level protein mani carcinoma phenotyp express p mdm breast cancer case set known studi investig express tumour suppressor protein p regul mdm use immunohistochemistri ghana breast cancer cohort
|
D001943
|
T191
|
34,695,136 |
porcin placenta hydrolys altern function food ingredi vitro antioxid antibacteri assess product bioactiv peptid anim base raw materi high depend enzymat hydrolysi porcin placenta underutil biomass thailand pig farm yet still sourc protein benefici compound porcin placenta could use protein substrat product enzymat hydrolys could employ function food ingredi futur goal studi enzymat produc porcin placenta hydrolys pph use three commerci enzym alcalas flavouzym papain evalu vitro antioxid antibacteri activ degre hydrolysi dh increas enzym load hydrolysi time increas dh govern enzym class maximum dh found use enzym min hydrolysi alcalas flavouzym papain depend enzym type dh peptid various size kda detect pph pph creat alcalas excel reduc capac metal chelat abil p wherea pph made flavourzym papain higher dpph abt inhibitori activ p papain deriv pph also strong antibacteri effect staphylococcus aureus escherichia coli clear zone valu mm mm respect p pph transport via gastrointestin tract model system antioxid characterist alter pph properti bioactiv thus influenc enzym type enzym concentr hydrolysi time use therefor pph produc porcin placenta categor antioxid antibacteri altern
|
D000975
|
T039;T121;T044;T123
|
34,695,133 |
new construct equal test scheme cloud assist wireless sensor network public key encrypt equal test enabl user determin whether two ciphertext contain inform without decrypt therefor may serv promis cryptograph techniqu cloud assist wireless sensor network cwsns maintain data privaci paper effici rsa equal test algorithm propos present scheme also handl attack base author abil precis propos scheme prove one way chosen ciphertext attack secur indistinguish chosen ciphertext attack moreov experiment evalu depict under scheme effici term encrypt decrypt equal test thus scheme may use practic solut context cwsns user may compar two ciphertext without decrypt
|
D000465
|
T170
|
34,695,131 |
region aggreg attent cnn diseas detect fruit imag diseas pest profound effect year harvest product agricultur precis accur detect diseas pest could facilit time treatment manag diseas pest lessen result loss economi health herein propos improv design diseas detect system plant imag
|
D016571
|
T170
|
34,695,130 |
preval depress associ factor among patient epilepsi univers gondar comprehens special hospit northwest ethiopia depress common overwhelm problem among patient epilepsi compromis qualiti life especi develop countri previous limit studi conduct use beck depress inventori tool ethiopia aim studi object determin preval depress associ factor among patient epilepsi
|
D006782;D006785
|
T093;T073
|
34,695,127 |
investig extern qualiti factor coupl coeffici novel sir base microstrip tri band bandpass filter articl new method develop design three band miniatur bandpass filter bpf use two asymmetr coupl reson one step discontinu open circuit uniform imped reson uir achiev global interoper microwav access wimax radio frequenc identif rfid applic first pair asymmetr step imped reson asir use implement dual band filter half wavelength uniform imped reson ad transmiss line achiev tripl band respons propos filter reson frequenc ghz ghz ghz fraction bandwidth respect adjust physic length ratio imped ratio r asymmetr sir propos fundament frequenc tripl bpf obtain moreov coupl coeffici ke extern qualiti factor qe investig reson inputoutput port transmiss line calcul use full wave em simul hfss addit five transmiss zero introduc near passband increas filter select final propos filter design fabric size mm g g g repres guid wavelength first passband simul measur result good correspond thus confirm design concept
|
D004581
|
T090
|
34,695,126 |
preval risk factor advers pregnanc outcom second trimest bacteri vaginosi among pregnant women bukavu democrat republ congo bacteri vaginosi bv common gynecolog condit women reproduct age associ advers pregnanc outcom democrat republ congo drc neonat mortal rate high percent preterm birth ptb low birth weight lbw lead caus studi address bv drc aim investig preval bv risk factor associ bv advers pregnanc outcom popul pregnant women bukavu drc
|
D011262
|
T079
|
34,695,124 |
unmet need hypercholesterolemia care low middl incom countri cross section studi nation repres survey preval hypercholesterolemia increas low middl incom countri lmic detail evid urgent need guid respons health system epidem studi sought quantifi unmet need hypercholesterolemia care among adult lmic
|
D007182
|
T081;T078
|
34,695,123 |
associ race health insur treatment dispar colon cancer retrospect analysi util nation popul databas unit state health insur status race independ impact colon cancer cc care deliveri outcom relat import factor explain racial insur dispar less clear howev studi aim determin associ interact race insur cc treatment dispar
|
D019992;D007348;D044469
|
T170;T098;T058
|
34,695,121 |
adjust famili life ground theori care children special healthcar need rural area thailand studi aim understand experi famili children special healthcar need rural area thailand ground theori gt employ understand famili experi care children special healthcar need cshcn rural area forti three famili member thirti four famili cshcn particip depth interview interview record transcrib constant compar method use data analysi code analysi adjust famili life emerg theori includ experienc negat effect manag home environ integr care communiti health system maintain famili normal studi describ process famili undergo tri care cshcn manag live maintain sens normalci theori provid intervent opportun health care profession deal complex home communiti ambulatori set throughout diseas trajectori also indic import take consider famili cultur background
|
D066296
|
T170
|
34,695,120 |
complex divers spars code prior improv recept field character macaqu v neuron system identif techniqu project pursuit regress model pprs convolut neural network cnns provid state art perform predict visual cortic neuron respons arbitrari input stimuli howev constitu kernel recov method often noisi lack coher structur make difficult understand under compon featur neuron recept field paper show use dictionari divers kernel complex shape learn natur scene base effici code theori front end pprs cnns improv perform neuron respons predict well algorithm data effici converg speed extens experiment result also indic spars code kernel provid import inform compon featur neuron recept field addit find model complex shape spars code front end signific better model standard orient select gabor filter front end model v neuron found exhibit complex pattern select show relat perform differ due two front end use produc sensit metric detect complex select v neuron
|
D008959
|
T170
|
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