Question: I use a bunch of Ubuntu 16.04 + Apache 2.4 + Django 1.10 + Python3.5 + wsgi + virtualenv.

The apache configuration ordered following

```
WSGIDaemonProcess myproject python-path/home/admin/web/domen.com/private/myprojectenv:/home/admin/web/domen.com/private/myprojectenv/lib/python3.5/site-packages
WSGIProcessGroup myproject
WSGIScriptAlias / /home/admin/web/domen.com/private/myproject/wsgi.py

```

wsgi.py standard

```
import os

from django.core.wsgi import get_wsgi_application

os.environ.setdefault("DJANGO_SETTINGS_MODULE", "myproject.settings")

application = get_wsgi_application()

```

Reinstall everything. Fat, you see the error 500.
 log:
`from django.core.wsgi import get_wsgi_application
 ImportError: No module named 'django'`

Answer: 
I got this error in VS 2022, while I was using EF version 6.1.3. I upgraded EF to version 6.4.4 and the issue got resolved. The .Net version was 4.8.
I had the same error in MVC 5 in VS 2022 but when I run it on VS 2019. That fixed my error.