Question: I found this in an ecological park:

[![enter image description here](https://i.stack.imgur.com/lrDeA.jpg)](https://i.stack.imgur.com/lrDeA.jpg)

*Cola* is actually a Latin word (a scientific one, referring to the plant), albeit its etymology is [African](https://en.wiktionary.org/wiki/cola#Etymology_1).

I am curious about whether it is "probably" the best-known Latin word in the world. If not, which one might it be? 

I think we could agree that *Cola* it is likely to be indeed very well known. We could also agree that it might be impossible to satisfactorily settle the issue of the "best-known" Latin word. Yet, hopefully, by comparing with other well-known words, we could gauge the extent to which that claim is likely to be true or not.

Answer: 
*Cola* is a Latinized form of *kola*, taken from some Niger-Congo language (it's not clear which) and applied to a genus of plants. It isn't a native Latin word and would have been unfamiliar to the Romans (except as the plural of the Greek borrowing *colon*, used as a technical term in rhetoric—completely unrelated).

So by these standards, I'd agree with K-HB and say the best-known Latinized name in the world is ***Jesus***, adapted from Greek *Iēsous*, adapted from Hebrew *Yešua*. It's similarly a foreign word respelled in the Latin alphabet, so it's at least as Latin as *Cola* is, possibly more so (since the adaptation happened while Latin was still alive and thriving).
The most famous Latin suffix (possibly), a case-ending, "-bus". For public-transport vehicles, in many countries, "-bus" appears somewhere in the word, even in Russia.