Question: If something unexpected (and incredibly unlikely) happens, should we take it as something deeper or just a fact of life?

Something highly unlikely and very positive happened at a very bad and negative point in my life, this event arguably showed a very different future to the one I imagined.

Don't know how to read into it, or how my actions should be after the event, should I embrace the change?

Answer: 
My teacher taught me that I must choose how I interpret such events in whichever way that produces the most wholesome mindstates.

So if thinking that this event was a sign from the hidden nature of things and held special significance makes you stronger, go for it with no hesitation. This is called, utilizing the power of faith.

In Varjrayana we learn to see hidden connections between things, hidden patterns and relationships. So having a sense of intuition for special events in one's life is important in our practice. In the absence of egoistic desires, and the baselessness of Emptiness, how else can we pick the course of action? So we choose to interpret things in a certain way, and act based on that. It's more an art than a science but there is a system to it.
In the [Sivaka Sutta (SN36.21)](https://www.accesstoinsight.org/tipitaka/sn/sn36/sn36.021.than.html), the Buddha explains that not all experiences are caused by kamma. Sometimes, it's just the weather or something else that's not extraordinarily significant. Not everything happens for a reason.

> 
> As he was sitting there, he said to the Blessed One, "Master Gotama,
>  there are some brahmans & contemplatives who are of this doctrine,
>  this view: Whatever an individual feels — pleasure, pain,
>  neither-pleasure-nor-pain — is entirely caused by what was done
>  before. Now what does Master Gotama say to that?"
> 
> 
> [The Buddha:] "There are cases where some feelings arise based on
>  bile. You yourself should know how some feelings arise based on
>  bile. Even the world is agreed on how some feelings arise based on
>  bile. So any brahmans & contemplatives who are of the doctrine & view
>  that whatever an individual feels — pleasure, pain,
>  neither-pleasure-nor-pain — is entirely caused by what was done before
>  — slip past what they themselves know, slip past what is agreed on by
>  the world. Therefore I say that those brahmans & contemplatives are
>  wrong."
> 
> 
> "There are cases where some feelings arise based on phlegm... based on
>  internal winds... based on a combination of bodily humors... from the
>  change of the seasons... from uneven care of the body... from harsh
>  treatment... from the result of kamma. You yourself should know how
>  some feelings arise from the result of kamma. Even the world is agreed
>  on how some feelings arise from the result of kamma. So any brahmans &
>  contemplatives who are of the doctrine & view that whatever an
>  individual feels — pleasure, pain, neither pleasure-nor-pain — is
>  entirely caused by what was done before — slip past what they
>  themselves know, slip past what is agreed on by the world. Therefore I
>  say that those brahmans & contemplatives are wrong."
> 
> 
>