Question: Home Depot/Lowes, etc., have boiled linseed oil at a much cheaper price than the local art store that I go to.

Are there any problem using boiled linseed oil from these home stores for oil painting applications, cleaning brushes etc?

Answer: 
Since you tagged this as oil-paint, I assume that is your intended use.

Actually, the BLO that is sold in art stores is the same stuff that is peddled in hardware stores, be they large or small.

So you can use the BLO from the gallon cans for anything that you might use the BLO purchased from anywhere else. 

**Edit:**

Note that not all linseed oil is "boiled linseed oil". BLO is not even actually boiled, but has additives that cause it to dry faster. Raw linseed oil is a slow drying product and may be refined. Stand oil is heated and is lighter in color. 

Most hardware stores carry only BLO. 

Raw linseed oil is harder to find except in specialty stores (e.g. art supply houses). Art stores are likely to carry multiple forms of linseed oil, but the one with the "Boiled linseed oil" label contains the same stuff as from the hardware stores.
To reduce the potential effects of yellowing/browning, I use hardware store BLO only with dark colors. I use only art store BLO for light colors. If you don't mind diluting colors with boiled linseed oil, go for it. It works great on the abstract stuff, usually the very large-sized works.

If you do indoor painting, use walnut oil, instead, which has the least odor of them all.

Never use paint thinner to clean brushes indoors. Refined mineral spirits from art stores may have less odor, but the fumes can still be hazardous to your health.

You can use baby oil to clean the brushes indoors. But make sure not to paint with baby oil. Dip the brush in linseed oil a few times and wipe before using it again.

As an aside, the best tip I have for oil painters is buy the orange grease-removing soap/cleaner sold at automotive stores. It cleans the grease mechanics suffer with, and it does a great job on cleaning your hands with oil paint.