Question: Imagine I have a generation ship that is heading to a nearby star system say 10 light years away, the average lifespan for the crew is 150 years on Earth and is expected to increase by about 5 years with each generation. No cryonic suspension due to the ban on any form of suspended animation on human by law and many policies are in place to ensure the population demography on board is healthy across every generation, so we can now laser focus on the economic and science aspects of this one way trip.

I believe delta v is important when planning trips within the solar system since as the name suggests it is the changes in velocity when jumping between orbits, what about jumping between star systems? Are we going to factor delta v for all interstellar flights regardless? if so why?

Answer: 
Yes, it's relevant. For a few reasons:

1. If your delta v is 0, you're not going anywhere. Sure this is a degenerate case, but if it were truly irrelevant it wouldn't matter. More practically, your delta v is going to need to be at least your star's escape velocity (barring exotic scenarios such as an extremely close approach by your target star.)
2. Stars are not at rest with respect to one another. So at a minimum, you will require at least the delta v of the relative speeds of your origin and destination systems.
3. Even in generational ships, time to destination matters. Realistically speaking, half your delta v is basically your cruising speed (ok, this doesn't hold as you get up into the really relativistic speeds, but in that case we're probably not talking generational ships.) So delta v will directly relate to how long your journey will take.
For interstellar journeys at sub light speeds the size of the DV is largely irrelevant in terms of the time it takes to complete the journey.
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Using your example and assuming an upper velocity (which is not mentioned in your question btw) of .10C the journey is going to take approx **100 years** with the acceleration & deceleration phases added on.

From the perspective of the crew it doesn't really matter if the ship takes 3 years to reach its 'cruising' velocity or just 3 weeks. With latter you end up with a 100 year (plus 6 weeks) long journey. With the former it takes 106 years. For all intents an purposes putting the 'pedal to the metal' only shaves a measly approx 6% off the total travel time. Hardly a huge saving for a generation ship. And of course the time saving only worsens with increases the distance. Double the distance the ship has to travel to 20 LY and at the high DV your only saving approx 3% on travel time over the lower DV. And on it goes.

Plus a lower DV is an easier engineering challenge which you want wherever possible. *Everything* on a generation ship has to be engineered to last because if breaks down and cant be repaired with what you have on board you screwed.