Medgemma-4b-it-half

This is a merge of pre-trained language models created using mergekit.

Merge Details

Merge Method

This model was merged using the Linear merge method.

Models Merged

The following models were included in the merge:

Configuration

The following YAML configuration was used to produce this model:

models:
  - model: google/gemma-3-4b-it
    parameters:
      weight: 1.0
  - model: google/medgemma-4b-it
    parameters: 
      weight: 1.618033988749
merge_method: linear 
tokenizer_source: google/gemma-3-4b-it

How to use

First, install the Transformers library. Gemma 3 is supported starting from transformers 4.50.0.

$ pip install -U transformers

Run the model directly

# pip install accelerate
from transformers import AutoProcessor, AutoModelForImageTextToText
from PIL import Image
import requests
import torch

model_id = "ChuGyouk/medgemma-4b-it-half" # "google/medgemma-4b-it"  "google/gemma-3-4b-it"  "ChuGyouk/medgemma-4b-it-half"

model = AutoModelForImageTextToText.from_pretrained(
    model_id,
    torch_dtype=torch.bfloat16,
    device_map="auto",
)
processor = AutoProcessor.from_pretrained(model_id)

## Text-only

messages = [
    {
        "role": "system",
        "content": [{"type": "text", "text": "You are a helpful medical assistant."}]
    },
    {
        "role": "user",
        "content": [{"type": "text", "text": "How do you differentiate bacterial from viral pneumonia?"}]
    }
]

inputs = processor.apply_chat_template(
    messages, add_generation_prompt=True, tokenize=True,
    return_dict=True, return_tensors="pt"
).to(model.device, dtype=torch.bfloat16)

input_len = inputs["input_ids"].shape[-1]

with torch.inference_mode():
    generation = model.generate(**inputs, max_new_tokens=4096, do_sample=False)
    generation = generation[0][input_len:]

decoded = processor.decode(generation, skip_special_tokens=True)
print(decoded)

"""
<gemma-3-4b-it>
Okay, let's talk about differentiating bacterial from viral pneumonia. It can be tricky because some symptoms overlap, but there are key differences that help doctors narrow it down. As a medical assistant, I play a vital role in gathering information that helps with this process. Here's a breakdown of how we differentiate them:

**1. Initial Symptoms โ€“ Often Overlapping:**

* **Common Symptoms:** Both bacterial and viral pneumonia often cause:
    * Cough (may be dry or produce mucus)
    * Fever
    * Shortness of breath
    * Chest pain (especially with deep breaths)
    * Fatigue
    * Rapid breathing
    * Confusion (more common in older adults)

**2. Key Differences โ€“ Where the Differentiation Happens:**

| Feature           | Bacterial Pneumonia           | Viral Pneumonia              |
|--------------------|-------------------------------|-------------------------------|
| **Onset**          | Often sudden and severe       | Can be gradual or sudden       |
| **Fever**          | Typically high and persistent   | May be lower or intermittent   |
| **Cough**          | Often produces thick, greenish or yellowish mucus (sputum) | May be dry initially, then produce white mucus |
| **Chest Pain**     | Often sharp and pleuritic (worse with breathing) | Can be less intense and more diffuse |
| **Pulse Rate**     | Usually elevated (tachycardia)  | May be elevated, but sometimes normal |
| **White Blood Cell Count** | Typically elevated (high)       | May be normal or slightly elevated |
| **Response to Antibiotics** | Usually improves significantly with antibiotics | Generally doesnโ€™t respond to antibiotics |


**3. Diagnostic Tests โ€“ The Tools We Use:**

* **Chest X-ray:** This is *crucial*.
    * **Bacterial Pneumonia:** Often shows a localized consolidation โ€“ a dense, white area on the X-ray representing an area of infection.  It often looks more โ€œpatchy.โ€
    * **Viral Pneumonia:**  May show more diffuse infiltrates โ€“ a more widespread pattern of hazy areas on the X-ray. It can sometimes look more like โ€œground-glass opacity.โ€
* **Blood Tests:**
    * **White Blood Cell Count (WBC):**  Elevated in both, but bacterial pneumonia usually has a *significantly* higher WBC count.
    * **Procalcitonin:** This blood test is increasingly used. Itโ€™s more specific to bacterial infections and can help guide antibiotic decisions.
* **Sputum Culture:**  If the patient is producing sputum, a sample can be sent to the lab to identify the specific bacteria causing the infection.  This is a key test for bacterial pneumonia.
* **PCR Testing (for Viruses):**  This test detects the genetic material of viruses (like influenza, RSV, COVID-19) in a sample (usually from the nose or throat).
* **Pulse Oximetry:** Measures oxygen saturation in the blood. Both types of pneumonia can cause low oxygen levels.

**4. Common Causes:**

* **Bacterial Pneumonia:** *Streptococcus pneumoniae* (pneumococcus) is the most common cause, but others include *Mycoplasma pneumoniae*, *Legionella*, and *Haemophilus influenzae*.
* **Viral Pneumonia:** Influenza (flu), Respiratory Syncytial Virus (RSV), COVID-19, Adenovirus, and Rhinovirus are frequent culprits.


**Important Disclaimer:** *I am an AI and cannot provide medical diagnoses. This information is for educational purposes only.  It is essential for a healthcare professional to evaluate the patient and order the appropriate tests to determine the cause of pneumonia.*

**My Role as a Medical Assistant:**

As a medical assistant, Iโ€™m responsible for:

* Taking a thorough patient history (including symptoms, travel history, exposure to sick individuals).
* Measuring vital signs (temperature, pulse, respiratory rate, blood pressure, oxygen saturation).
* Collecting sputum samples for testing.
* Preparing the patient for diagnostic tests (X-rays, blood draws).
* Assisting the physician with the examination and treatment plan.

---

**Resources for Further Information:**

* **Centers for Disease Control and Prevention (CDC) - Pneumonia:** [https://www.cdc.gov/pneumonia/index.htm](https://www.cdc.gov/pneumonia/index.htm)
* **Mayo Clinic - Pneumonia:** [https://www.mayoclinic.org/diseases-conditions/pneumonia/symptoms-causes/syc-20354307](https://www.mayoclinic.org/diseases-conditions/pneumonia/symptoms-causes/syc-20354307)

Do you want me to delve deeper into a specific aspect, such as:

*   Specific diagnostic tests?
*   Treatment options for each type of pneumonia?
*   How I would gather information from a patient about their symptoms?
</gemma-3-4b-it>
<medgemma-4b-it>
Okay, I can help you understand how to differentiate between bacterial and viral pneumonia. It's important to remember that I am an AI and cannot provide medical diagnoses. This information is for educational purposes only, and you should always consult with a qualified healthcare professional for any health concerns.

Here's a breakdown of the key differences, along with some important considerations:

**Key Differences Between Bacterial and Viral Pneumonia:**

| Feature          | Bacterial Pneumonia                                  | Viral Pneumonia                                      |
|-------------------|-------------------------------------------------------|-------------------------------------------------------|
| **Cause**         | Bacteria (e.g., *Streptococcus pneumoniae*, *Haemophilus influenzae*) | Viruses (e.g., influenza virus, respiratory syncytial virus (RSV), adenovirus) |
| **Onset**         | Often sudden and rapid                               | Can be gradual or sudden                             |
| **Symptoms**      | *   High fever (often 102ยฐF or higher)             *   Productive cough (often with thick, purulent sputum) *   Chest pain (often pleuritic, meaning it worsens with breathing) *   Rapid breathing (tachypnea) *   Rapid heart rate (tachycardia) *   Confusion or altered mental status (especially in older adults) *   Bluish skin color (cyanosis) | *   Fever (may be lower than bacterial pneumonia) *   Dry cough (often non-productive) *   Fatigue *   Muscle aches *   Headache *   Loss of appetite *   Shortness of breath (dyspnea) |
| **Cough**         | Typically productive (mucus-producing)                | Typically dry (non-productive)                       |
| **Sputum**        | Often thick, yellow, green, or rusty-colored          | May be clear or slightly colored                       |
| **Chest X-ray**   | Often shows consolidation (dense area of infection)   | May show patchy infiltrates or consolidation         |
| **Treatment**     | Antibiotics                                           | Antiviral medications (if specific to the virus), supportive care (rest, fluids, oxygen) |
| **Progression**   | Can progress rapidly to severe illness and death       | Can range from mild to severe, but often less severe than bacterial pneumonia |
| **Complications** | Bacteremia (bloodstream infection), sepsis, ARDS (acute respiratory distress syndrome) | Secondary bacterial pneumonia, ARDS, myocarditis (inflammation of the heart muscle) |

**Important Considerations and Overlap:**

*   **Overlap:** It's crucial to understand that the symptoms of bacterial and viral pneumonia can overlap significantly. This makes it difficult to differentiate between them based on symptoms alone.
*   **Age:** The presentation can vary depending on the patient's age. For example, in very young children or older adults, the symptoms may be less specific.
*   **Underlying Conditions:** People with underlying health conditions (e.g., COPD, heart disease, diabetes) may have a more severe course of either type of pneumonia.
*   **Testing:** The most definitive way to differentiate between bacterial and viral pneumonia is through laboratory testing. This may include:
    *   **Sputum Gram stain and culture:** To identify the specific bacteria causing the infection.
    *   **Blood cultures:** To check for bacteria in the bloodstream.
    *   **Viral PCR testing:** To detect the presence of specific viruses in the respiratory secretions.
    *   **Chest X-ray:** While not diagnostic, it can help visualize the extent of the infection and rule out other conditions.
*   **Clinical Judgment:** Ultimately, the diagnosis of pneumonia and its cause is based on a combination of clinical findings, history, physical examination, and laboratory results. A healthcare professional will use their clinical judgment to determine the most likely diagnosis and initiate appropriate treatment.

**In summary:**

While there are some key differences between bacterial and viral pneumonia, it's important to remember that these differences can be subtle and that the symptoms can overlap. A healthcare professional is best equipped to differentiate between the two and provide appropriate treatment.

**Disclaimer:** This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional for any health concerns.
</medgemma-4b-it>
<medgemma-4b-it-half>
Okay, I can help you understand how we differentiate between bacterial and viral pneumonia. It's important to remember that I am an AI and cannot provide medical diagnoses. This information is for educational purposes only, and you should always consult with a qualified healthcare professional for any health concerns.

Here's a breakdown of the key differences and how we approach diagnosis:

**1. Symptoms:**

While some symptoms overlap, there are some clues that can point towards one type over the other:

*   **Fever:** Both bacterial and viral pneumonia can cause fever. However, bacterial pneumonia often presents with a higher, more persistent fever.
*   **Cough:** Both types cause a cough. Bacterial pneumonia often produces a *productive cough* (coughing up mucus or phlegm), which can be yellow, green, or even bloody. Viral pneumonia is more likely to be a dry cough.
*   **Shortness of Breath:** Both can cause shortness of breath, but it may be more pronounced in bacterial pneumonia due to the inflammation and fluid buildup in the lungs.
*   **Chest Pain:** Chest pain is common in both. Bacterial pneumonia chest pain is often pleuritic (sharp and worsens with breathing).
*   **Fatigue:** Both can cause fatigue.
*   **Headache and Muscle Aches:** These are more common with viral infections.
*   **Sore Throat:** More common with viral infections.
*   **Runny Nose and Congestion:** More common with viral infections (like the flu or a cold).

**2. Physical Examination Findings:**

*   **Lung Sounds:**
    *   **Bacterial Pneumonia:** Often reveals crackles (rales) or wheezes, especially in the lower lobes of the lungs.  The sound can be more localized.
    *   **Viral Pneumonia:** May have crackles, but they are often more diffuse and less pronounced.
*   **Heart Rate and Respiratory Rate:** Both can increase, but bacterial pneumonia may have a higher respiratory rate.
*   **Oxygen Saturation:** Low oxygen saturation (SpO2) is common in both, but may be more severe in bacterial pneumonia.

**3. Diagnostic Tests:**

This is where the real differentiation happens.  We use a combination of tests:

*   **Chest X-ray:** This is the primary imaging test.
    *   **Bacterial Pneumonia:** Often shows a localized consolidation (an area of dense, white opacity) in one or more lobes of the lung. The consolidation is usually well-defined.
    *   **Viral Pneumonia:** May show more diffuse infiltrates (patchy areas of increased density) throughout the lungs, or may be normal in some cases.  It may also show areas of consolidation, but they are often less distinct.
*   **Blood Tests:**
    *   **White Blood Cell Count (WBC):**  A high WBC count (leukocytosis) is often seen in bacterial infections, indicating the body's response to the infection. Viral infections may cause a normal or slightly elevated WBC count.
    *   **C-Reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR):** These are markers of inflammation and are often elevated in both bacterial and viral pneumonia, but may be higher in bacterial infections.
    *   **Blood Cultures:**  If the patient is severely ill, blood cultures are taken to look for bacteria in the bloodstream (bacteremia), which can indicate a more serious infection.
*   **Sputum Culture:**  If the patient is producing sputum, a sample can be sent to the lab to identify the specific bacteria causing the infection. This is a crucial test for guiding antibiotic treatment.
*   **PCR (Polymerase Chain Reaction) Testing:** This is a highly sensitive test that can detect the genetic material of viruses in the respiratory secretions (e.g., sputum, nasal swabs). It can identify specific viruses like influenza, RSV, adenovirus, and COVID-19.
*   **Other Tests:** Depending on the patient's symptoms and risk factors, other tests may be considered, such as a CT scan of the chest, bronchoscopy, or lung biopsy.

**4. Treatment:**

*   **Bacterial Pneumonia:** Treated with antibiotics. The specific antibiotic will depend on the type of bacteria identified in the sputum culture or blood cultures.
*   **Viral Pneumonia:**  Treatment is primarily supportive, focusing on relieving symptoms and preventing complications.  Antiviral medications are available for some viruses (e.g., influenza, RSV), but they are not always effective and must be started early in the course of the illness.  Rest, fluids, and over-the-counter medications (e.g., pain relievers, cough suppressants) can help manage symptoms.

**Important Considerations:**

*   **Overlap:** It's important to note that there can be overlap in the symptoms and findings of bacterial and viral pneumonia.  Sometimes, it can be difficult to distinguish between the two based on clinical presentation alone.
*   **Severity:** Bacterial pneumonia is often more severe than viral pneumonia and can lead to complications such as sepsis, respiratory failure, and death.
*   **Underlying Conditions:** Patients with underlying health conditions (e.g., COPD, asthma, diabetes, weakened immune systems) are at higher risk for developing pneumonia and may have a more severe course of illness.

**In summary, differentiating between bacterial and viral pneumonia requires a careful evaluation of the patient's symptoms, physical examination findings, and diagnostic test results. A healthcare professional will use this information to determine the most appropriate treatment plan.**

**Disclaimer:** *This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.*
</medgemma-4b-it-half>
"""

print("======================================")
## Multimodal

# Image attribution: Stillwaterising, CC0, via Wikimedia Commons
image_url = "https://upload.wikimedia.org/wikipedia/commons/c/c8/Chest_Xray_PA_3-8-2010.png"
image = Image.open(requests.get(image_url, headers={"User-Agent": "example"}, stream=True).raw)

messages = [
    {
        "role": "system",
        "content": [{"type": "text", "text": "You are an expert radiologist."}]
    },
    {
        "role": "user",
        "content": [
            {"type": "text", "text": "Describe this X-ray"},
            {"type": "image", "image": image}
        ]
    }
]

inputs = processor.apply_chat_template(
    messages, add_generation_prompt=True, tokenize=True,
    return_dict=True, return_tensors="pt"
).to(model.device, dtype=torch.bfloat16)

input_len = inputs["input_ids"].shape[-1]

with torch.inference_mode():
    generation = model.generate(**inputs, max_new_tokens=4096, do_sample=False)
    generation = generation[0][input_len:]

decoded = processor.decode(generation, skip_special_tokens=True)
print(decoded)

"""
<gemma-3-4b-it>
Okay, let's analyze this chest X-ray. Here's a detailed description from a radiologist's perspective:

**Overall Impression:**

This is a PA (Posterior-Anterior) chest radiograph. The patient is in an upright position, with arms at their sides. The image demonstrates some concerning findings, primarily in the right lower lobe.

**Detailed Findings:**

1. **Lungs:**
   * **Right Lower Lobe:** There is a significant area of increased opacity in the right lower lobe. This is best described as a **patchy consolidation**. It appears as a hazy, irregular density, disrupting the normal lung markings. This is highly suggestive of pneumonia. The density is more prominent in the lower portion of the lobe.
   * **Left Lung:** The left lung appears clear with normal vascular markings. There is no evidence of consolidation, effusion, or masses.
   * **Lung Fields:** The lung fields are otherwise unremarkable, with normal vascular distribution.

2. **Heart:** The cardiac silhouette appears within normal limits in size and shape.

3. **Mediastinum:** The mediastinum (the space between the lungs containing the heart, great vessels, and trachea) appears unremarkable. The trachea is midline.

4. **Bones:** The visualized bony structures (ribs, clavicles, scapulae) appear intact without acute fractures.

5. **Pleura:** The pleura (lining of the lungs) appears unremarkable.

6. **Soft Tissues:** The soft tissues of the chest wall appear normal.

7. **Other:** There is a small, subtle, and likely incidental, subcutaneous air bubble near the clavicle on the left side.


**Possible Diagnosis:**

Based on the findings, the most likely diagnosis is **right lower lobe pneumonia**. The patchy consolidation is a classic radiographic sign of this condition.

**Recommendations:**

* **Clinical Correlation:** This radiographic finding *must* be correlated with the patient's clinical history, symptoms (cough, fever, shortness of breath), and physical examination.
* **Further Investigation:**  A follow-up chest X-ray in 48-72 hours would be appropriate to assess for resolution or progression of the consolidation.  Consider a CT scan of the chest if the clinical picture is complex or if the pneumonia is not responding to treatment.
* **Treatment:**  Antibiotic therapy would likely be initiated based on the clinical suspicion of pneumonia.

**Disclaimer:** *This interpretation is based solely on the provided X-ray image and is for informational purposes only. It does not constitute a definitive diagnosis and should be interpreted in conjunction with the patient's complete clinical information by a qualified physician.*

---

**To help me refine my assessment, could you tell me:**

*   What is the patient's age and gender?
*   Are there any known underlying medical conditions?
*   What were the clinical indications for this X-ray (e.g., cough, fever, shortness of breath)?
</gemma-3-4b-it>
<medgemma-4b-it>
Okay, here's a description of the chest X-ray based on the image provided:

**Overall Impression:**

The image shows a standard PA (Posterior-Anterior) chest X-ray. The lungs appear clear, and there are no obvious signs of acute pathology.

**Specific Findings:**

*   **Heart Size:** The heart size appears within normal limits.
*   **Mediastinum:** The mediastinum (the space between the lungs containing the heart, great vessels, trachea, etc.) is unremarkable.
*   **Lungs:** The lungs are clear bilaterally, with no evidence of consolidation, nodules, masses, or significant infiltrates.
*   **Pleura:** The pleural surfaces are clear, with no evidence of pleural effusion or pneumothorax.
*   **Bones:** The ribs and clavicles appear intact.
*   **Soft Tissues:** The soft tissues of the chest wall are unremarkable.
*   **Diaphragm:** The diaphragms are well-defined.

**In summary:**

The chest X-ray shows a normal appearance of the lungs, heart, mediastinum, and pleura. There are no acute findings.

**Important Considerations:**

*   This is a single image, and a complete evaluation requires reviewing the entire series of images, including the lateral view.
*   The patient's clinical history and symptoms are crucial for interpreting the X-ray.
*   This interpretation is based solely on the provided image and does not replace a comprehensive clinical evaluation.

**Disclaimer:** This is a preliminary interpretation based on a single image. A definitive diagnosis requires a complete clinical evaluation and potentially additional imaging studies.
</medgemma-4b-it>
<medgemma-4b-it-half>
Okay, I've reviewed the X-ray image you provided.  Based on the limited information and the lack of anatomical landmarks, I can only offer a very general description.

**Overall Impression:**

The image appears to show a dense, opaque area occupying a significant portion of the visualized field.  It's difficult to determine the exact location or size without more context.

**Possible Considerations (Without More Information):**

*   **Foreign Body:** The dense opacity could represent a foreign body, such as a metallic object or a dense mass.
*   **Bone:** It could be a portion of bone, particularly if the image is of the chest or abdomen.
*   **Mass/Tumor:** Depending on the location, it could be a mass or tumor.
*   **Calcification:** It could be a calcified structure, such as a stone or a calcified nodule.
*   **Artifact:** It's also possible that the opacity is an artifact caused by the X-ray machine or the patient's positioning.

**Limitations:**

*   **Lack of Anatomical Context:** Without knowing the patient's age, gender, and clinical history, it's impossible to provide a more specific diagnosis.
*   **Limited Image Quality:** The image is very low resolution, making it difficult to assess the details.
*   **No Adjacent Structures:** The absence of surrounding structures makes it hard to determine the location and size of the opacity.

**Next Steps:**

To provide a more accurate diagnosis, I would need:

*   **Patient History:** Age, gender, medical history, and any relevant symptoms.
*   **Clinical Indication:** The reason for the X-ray.
*   **Additional Imaging:**  A CT scan or MRI would provide much more detailed information.
*   **More Detailed X-ray:** A higher resolution image with better contrast would be helpful.

**Disclaimer:** This is a preliminary assessment based on a very limited image. It is not a definitive diagnosis and should not be used to make any medical decisions. A qualified radiologist should interpret the image in the context of the patient's clinical presentation.
</medgemma-4b-it-half>
"""
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