---
license: apache-2.0
---
## 🚀 Introduction (ProtSSN)

Fusion of protein **sequence and structural** information, using **denoising** pre-training network for **protein engineering** (**zero-shot**).

## 📑 Github

https://github.com/tyang816/ProtSSN

## 🙌 Citation

Please cite our work if you have used our code or data for **dry experiment testing/wet experiment directed evolution**. We are pleased to see improvements in the subsequent work.

```
@article{tan2023protssn,
  title={Semantical and Topological Protein Encoding Toward Enhanced Bioactivity and Thermostability},
  author={Tan, Yang and Zhou, Bingxin and Zheng, Lirong and Fan, Guisheng and Hong, Liang},
  journal={bioRxiv},
  pages={2023--12},
  year={2023},
  publisher={Cold Spring Harbor Laboratory}
}
```