readme: ---
  license: mit
  ---
  
  # ESMFold
  
  ESMFold is a state-of-the-art end-to-end protein folding model based on an ESM-2 backbone. It does not require any lookup or MSA step, and therefore does not require any external databases to be present in order to make predictions. As a result, inference time is very significantly faster than AlphaFold2. For details on the model architecture and training, please refer to the [accompanying paper](https://www.biorxiv.org/content/10.1101/2022.07.20.500902v2).
  
  If you're interested in using ESMFold in practice, please check out the associated [tutorial notebook](https://colab.research.google.com/github/huggingface/notebooks/blob/main/examples/protein_folding.ipynb).