Previous studies on the Tridimensional Personality Questionnaire (TPQ) in patients with panic disorder (PD) have failed to support Cloninger's hypothesis that PD is not specifically related to any of the 3 personality dimensions. In most studies, patients with PD had clearly higher harm avoidance (HA) scores. This finding, however, could be biased by comorbid personality disorders in the samples. In the present study, we examined the TPQ scores in 43 patients without comorbid personality disorders.