. This loss was more pronounced at the caudad level where the loss of signal intensity was similar to that seen at the fused levels; (3) the histologic analysis showed severe degenerative changes with a lack of live cells in the nucleus pulposus and in the endplate at the caudad adjacent level. At the cephalad level, live cells were apparent (albeit few) in the nucleus pulposus, and there was a more normal looking endplate with live cells.